Caenorhabditis elegans

0 known processes

ttm-4 (CELE_F42C5.10)

Protein TTM-4

ttm-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 1634 0.548
mitotic nuclear envelope reassembly GO:0007084 3 0.525
multicellular organismal reproductive process GO:0048609 815 0.502
post embryonic development GO:0009791 2152 0.500
embryo development GO:0009790 3052 0.488
nuclear pore distribution GO:0031081 2 0.478
embryo development ending in birth or egg hatching GO:0009792 2992 0.402
body morphogenesis GO:0010171 620 0.400
protein metabolic process GO:0019538 422 0.396
chromosome organization GO:0051276 104 0.373
cell motility GO:0048870 313 0.365
growth GO:0040007 562 0.310
single organism reproductive process GO:0044702 1196 0.295
localization of cell GO:0051674 313 0.290
sexual reproduction GO:0019953 546 0.283
muscle organ morphogenesis GO:0048644 4 0.270
nuclear pore localization GO:0051664 2 0.269
single organism transport GO:0044765 447 0.263
multicellular organism reproduction GO:0032504 819 0.260
mitotic nuclear division GO:0007067 89 0.252
reproductive system development GO:0061458 850 0.236
cytoskeleton organization GO:0007010 339 0.231
positive regulation of developmental growth GO:0048639 354 0.229
gamete generation GO:0007276 461 0.225
regulation of rna biosynthetic process GO:2001141 165 0.218
developmental growth GO:0048589 412 0.216
positive regulation of multicellular organismal process GO:0051240 417 0.200
establishment of localization GO:0051234 1171 0.197
positive regulation of growth GO:0045927 369 0.187
mitotic cell cycle process GO:1903047 194 0.180
muscle tissue development GO:0060537 1 0.178
macromolecule localization GO:0033036 771 0.176
positive regulation of transcription dna templated GO:0045893 102 0.172
positive regulation of multicellular organism growth GO:0040018 352 0.172
vesicle mediated transport GO:0016192 852 0.171
organic cyclic compound biosynthetic process GO:1901362 195 0.168
genitalia development GO:0048806 741 0.167
cellular component movement GO:0006928 388 0.166
oocyte construction GO:0007308 2 0.166
organelle organization GO:0006996 783 0.165
cell development GO:0048468 696 0.165
positive regulation of developmental process GO:0051094 408 0.165
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.165
nucleus organization GO:0006997 38 0.162
regulation of developmental growth GO:0048638 389 0.158
developmental process involved in reproduction GO:0003006 1165 0.157
actin cytoskeleton organization GO:0030036 184 0.156
organ development GO:0048513 1102 0.154
germ cell development GO:0007281 351 0.153
tube development GO:0035295 126 0.153
multi organism behavior GO:0051705 389 0.152
regulation of organelle organization GO:0033043 164 0.149
transport GO:0006810 1093 0.144
organelle fission GO:0048285 363 0.142
localization within membrane GO:0051668 2 0.141
transcription dna templated GO:0006351 168 0.141
multi organism reproductive process GO:0044703 867 0.138
reproductive behavior GO:0019098 387 0.137
receptor mediated endocytosis GO:0006898 715 0.136
gonad development GO:0008406 840 0.136
striated muscle cell differentiation GO:0051146 158 0.135
regulation of multicellular organismal process GO:0051239 726 0.134
regulation of growth GO:0040008 409 0.133
meiotic nuclear division GO:0007126 300 0.133
nuclear envelope reassembly GO:0031468 4 0.131
cell cell signaling GO:0007267 118 0.129
female gamete generation GO:0007292 254 0.127
chromosome segregation GO:0007059 180 0.126
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.126
inductive cell migration GO:0040039 145 0.119
multicellular organism growth GO:0035264 385 0.119
positive regulation of cellular metabolic process GO:0031325 178 0.118
nucleic acid metabolic process GO:0090304 299 0.116
cell migration GO:0016477 306 0.115
tube morphogenesis GO:0035239 79 0.112
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.112
single organism organelle organization GO:1902589 501 0.112
regulation of developmental process GO:0050793 684 0.111
endocytosis GO:0006897 819 0.111
striated muscle cell development GO:0055002 157 0.110
rna metabolic process GO:0016070 228 0.109
protein localization GO:0008104 205 0.109
transcription from rna polymerase ii promoter GO:0006366 149 0.106
positive regulation of rna biosynthetic process GO:1902680 102 0.106
establishment of localization in cell GO:0051649 318 0.105
protein complex subunit organization GO:0071822 280 0.103
actin filament based process GO:0030029 191 0.102
positive regulation of nucleic acid templated transcription GO:1903508 102 0.101
positive regulation of cellular process GO:0048522 332 0.100
nucleus localization GO:0051647 55 0.100
mitochondrion organization GO:0007005 20 0.099
cellular protein localization GO:0034613 75 0.099
myosin filament assembly GO:0031034 138 0.098
signaling GO:0023052 401 0.097
single organism localization GO:1902578 518 0.097
head development GO:0060322 1 0.096
regulation of transcription dna templated GO:0006355 164 0.096
apoptotic process GO:0006915 478 0.095
reproductive structure development GO:0048608 850 0.093
regulation of multicellular organism growth GO:0040014 373 0.092
cellular component assembly involved in morphogenesis GO:0010927 183 0.091
response to chemical GO:0042221 356 0.090
nucleobase containing compound metabolic process GO:0006139 406 0.090
tissue development GO:0009888 112 0.090
development of primary sexual characteristics GO:0045137 840 0.090
sex differentiation GO:0007548 909 0.087
organic substance biosynthetic process GO:1901576 323 0.084
chromatin organization GO:0006325 32 0.082
striated muscle myosin thick filament assembly GO:0071688 138 0.082
molting cycle GO:0042303 281 0.082
microtubule based process GO:0007017 182 0.082
actomyosin structure organization GO:0031032 154 0.081
chromatin modification GO:0016568 32 0.081
protein catabolic process GO:0030163 162 0.080
oviposition GO:0018991 364 0.080
macromolecule biosynthetic process GO:0009059 250 0.079
muscle cell differentiation GO:0042692 171 0.079
organelle assembly GO:0070925 214 0.078
negative regulation of gene expression GO:0010629 217 0.078
cellular macromolecular complex assembly GO:0034622 184 0.077
regulation of biological quality GO:0065008 741 0.077
cell division GO:0051301 262 0.076
death GO:0016265 547 0.075
cellular component assembly GO:0022607 293 0.074
cellular protein complex assembly GO:0043623 178 0.074
multicellular organismal reproductive behavior GO:0033057 384 0.074
er nucleus signaling pathway GO:0006984 66 0.074
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.073
regulation of cellular component organization GO:0051128 248 0.073
cellular protein complex localization GO:0034629 3 0.073
digestive tract morphogenesis GO:0048546 76 0.072
rna biosynthetic process GO:0032774 169 0.072
lipid storage GO:0019915 565 0.071
protein complex assembly GO:0006461 186 0.071
regulation of cell motility GO:2000145 57 0.069
positive regulation of rna metabolic process GO:0051254 103 0.069
programmed cell death GO:0012501 500 0.068
cellular component biogenesis GO:0044085 297 0.068
synaptic transmission GO:0007268 106 0.068
nucleic acid templated transcription GO:0097659 169 0.067
multi organism reproductive behavior GO:0044705 387 0.067
cellular macromolecule localization GO:0070727 75 0.067
macromolecular complex subunit organization GO:0043933 320 0.066
regulation of macromolecule biosynthetic process GO:0010556 189 0.065
positive regulation of macromolecule metabolic process GO:0010604 149 0.065
anatomical structure formation involved in morphogenesis GO:0048646 250 0.065
maintenance of location GO:0051235 580 0.065
myofibril assembly GO:0030239 154 0.064
negative regulation of cellular process GO:0048523 239 0.063
muscle structure development GO:0061061 191 0.063
cellular nitrogen compound biosynthetic process GO:0044271 192 0.062
protein complex biogenesis GO:0070271 186 0.062
multi multicellular organism process GO:0044706 390 0.062
signal transduction GO:0007165 317 0.062
negative regulation of gene expression epigenetic GO:0045814 2 0.061
cell cycle GO:0007049 526 0.061
cellular macromolecule biosynthetic process GO:0034645 247 0.060
cell fate commitment GO:0045165 139 0.060
aromatic compound biosynthetic process GO:0019438 192 0.059
regulation of rna metabolic process GO:0051252 173 0.059
lipid localization GO:0010876 573 0.058
regulation of macromolecule metabolic process GO:0060255 421 0.058
regulation of reproductive process GO:2000241 66 0.058
regulation of cellular biosynthetic process GO:0031326 189 0.057
intracellular transport GO:0046907 77 0.057
biosynthetic process GO:0009058 323 0.056
regulation of cytoskeleton organization GO:0051493 41 0.056
macromolecule catabolic process GO:0009057 202 0.056
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.055
cell death GO:0008219 547 0.055
regulation of nucleic acid templated transcription GO:1903506 165 0.055
cellular localization GO:0051641 360 0.055
determination of adult lifespan GO:0008340 812 0.055
gene expression GO:0010467 412 0.053
positive regulation of cell projection organization GO:0031346 4 0.053
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.053
cellular biosynthetic process GO:0044249 315 0.049
multicellular organismal aging GO:0010259 812 0.048
regulation of gene expression epigenetic GO:0040029 163 0.048
regulation of metabolic process GO:0019222 478 0.047
meiotic cell cycle GO:0051321 335 0.047
negative regulation of biological process GO:0048519 567 0.046
cellular response to stress GO:0033554 162 0.045
protein modification process GO:0036211 207 0.045
establishment or maintenance of cell polarity GO:0007163 63 0.045
cell cycle process GO:0022402 482 0.044
cellular protein metabolic process GO:0044267 279 0.043
regulation of nuclear division GO:0051783 115 0.043
aging GO:0007568 812 0.043
cellular component morphogenesis GO:0032989 318 0.043
muscle cell development GO:0055001 158 0.043
maintenance of protein location in cell GO:0032507 12 0.042
protein complex localization GO:0031503 3 0.042
organ morphogenesis GO:0009887 67 0.041
positive regulation of cellular biosynthetic process GO:0031328 109 0.041
regulation of biosynthetic process GO:0009889 189 0.041
single organism signaling GO:0044700 401 0.040
copulation GO:0007620 2 0.040
regulation of nitrogen compound metabolic process GO:0051171 222 0.039
nuclear migration GO:0007097 54 0.039
negative regulation of transcription dna templated GO:0045892 53 0.039
regulation of mitochondrion organization GO:0010821 1 0.038
cuticle development GO:0042335 100 0.038
collagen and cuticulin based cuticle development GO:0040002 99 0.037
myosin filament organization GO:0031033 138 0.037
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.037
establishment of nucleus localization GO:0040023 55 0.036
regulation of cellular localization GO:0060341 42 0.036
digestive tract development GO:0048565 122 0.035
regulation of gene expression GO:0010468 366 0.034
regulation of chromosome segregation GO:0051983 20 0.034
sodium ion transmembrane transport GO:0035725 8 0.033
regulation of apoptotic signaling pathway GO:2001233 1 0.033
regulation of response to stimulus GO:0048583 243 0.033
muscle contraction GO:0006936 43 0.033
attachment of mitotic spindle microtubules to kinetochore GO:0051315 6 0.032
regulation of actin filament based process GO:0032970 22 0.032
defense response GO:0006952 296 0.031
regulation of cell projection organization GO:0031344 38 0.031
system process GO:0003008 136 0.030
heterocycle biosynthetic process GO:0018130 187 0.030
response to acid chemical GO:0001101 4 0.030
positive regulation of cell migration GO:0030335 3 0.029
hermaphrodite genitalia development GO:0040035 734 0.029
immune response GO:0006955 192 0.029
secretion GO:0046903 147 0.029
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.029
digestive system development GO:0055123 122 0.028
regulation of cell communication GO:0010646 176 0.028
gene silencing GO:0016458 143 0.028
regulation of cellular metabolic process GO:0031323 305 0.028
adult behavior GO:0030534 3 0.027
negative regulation of neurogenesis GO:0050768 4 0.027
negative regulation of metabolic process GO:0009892 240 0.027
skeletal muscle organ development GO:0060538 3 0.027
protein polymerization GO:0051258 26 0.026
negative regulation of cell cycle GO:0045786 53 0.026
response to wounding GO:0009611 4 0.026
maintenance of protein location GO:0045185 15 0.026
negative regulation of rna biosynthetic process GO:1902679 53 0.025
apoptotic mitochondrial changes GO:0008637 2 0.025
regulation of cell morphogenesis GO:0022604 40 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.025
single organism behavior GO:0044708 83 0.025
negative regulation of cell communication GO:0010648 61 0.024
negative regulation of response to stimulus GO:0048585 73 0.024
organic substance catabolic process GO:1901575 294 0.024
protein localization to nucleus GO:0034504 11 0.024
negative regulation of macromolecule metabolic process GO:0010605 229 0.023
negative regulation of cellular metabolic process GO:0031324 95 0.023
epithelial tube morphogenesis GO:0060562 1 0.023
regulation of cellular protein metabolic process GO:0032268 75 0.023
tissue morphogenesis GO:0048729 65 0.023
ovulation GO:0030728 33 0.022
regulation of cell division GO:0051302 142 0.022
negative regulation of rna metabolic process GO:0051253 53 0.022
regulation of cell migration GO:0030334 55 0.022
positive regulation of gene expression GO:0010628 112 0.022
regulation of primary metabolic process GO:0080090 292 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.021
adult locomotory behavior GO:0008344 1 0.021
membrane organization GO:0061024 135 0.020
macromolecular complex assembly GO:0065003 193 0.020
organic substance transport GO:0071702 113 0.020
single organism intracellular transport GO:1902582 70 0.020
rna localization GO:0006403 3 0.020
nervous system development GO:0007399 253 0.020
positive regulation of metabolic process GO:0009893 187 0.020
positive regulation of neuron differentiation GO:0045666 4 0.019
response to oxygen levels GO:0070482 22 0.019
response to abiotic stimulus GO:0009628 152 0.019
positive regulation of biosynthetic process GO:0009891 109 0.019
negative regulation of neuron differentiation GO:0045665 4 0.018
cytokinesis GO:0000910 80 0.018
organelle localization GO:0051640 127 0.018
positive regulation of neurogenesis GO:0050769 4 0.018
oocyte development GO:0048599 44 0.018
positive regulation of protein metabolic process GO:0051247 45 0.018
regulation of mitotic cell cycle GO:0007346 76 0.018
negative regulation of cellular biosynthetic process GO:0031327 65 0.018
2 deoxyribonucleotide metabolic process GO:0009394 2 0.017
oocyte differentiation GO:0009994 45 0.017
nucleobase containing compound biosynthetic process GO:0034654 184 0.017
catabolic process GO:0009056 318 0.017
cellular protein modification process GO:0006464 207 0.016
fertilization GO:0009566 63 0.016
regulation of localization GO:0032879 194 0.016
regulation of epithelial cell proliferation GO:0050678 1 0.016
neuron recognition GO:0008038 83 0.016
negative regulation of biosynthetic process GO:0009890 65 0.016
macromolecule modification GO:0043412 218 0.016
male gamete generation GO:0048232 41 0.016
behavior GO:0007610 527 0.016
protein localization to organelle GO:0033365 37 0.016
negative regulation of signaling GO:0023057 61 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.016
negative regulation of nucleic acid templated transcription GO:1903507 53 0.016
single organism cellular localization GO:1902580 72 0.015
intracellular receptor signaling pathway GO:0030522 2 0.015
small molecule metabolic process GO:0044281 186 0.015
positive regulation of chromosome organization GO:2001252 2 0.015
pattern specification process GO:0007389 59 0.015
response to biotic stimulus GO:0009607 101 0.015
histone modification GO:0016570 30 0.015
regulation of signaling GO:0023051 172 0.014
male mating behavior GO:0060179 26 0.014
single organism membrane organization GO:0044802 35 0.014
cell recognition GO:0008037 85 0.014
response to endoplasmic reticulum stress GO:0034976 71 0.014
cell surface receptor signaling pathway GO:0007166 149 0.014
regulation of signal transduction GO:0009966 135 0.014
lateral inhibition GO:0046331 3 0.014
mating GO:0007618 34 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.014
response to bacterium GO:0009617 86 0.014
oogenesis GO:0048477 229 0.014
regulation of cell development GO:0060284 49 0.013
regulation of actin cytoskeleton organization GO:0032956 17 0.013
synaptic target recognition GO:0008039 3 0.013
regulation of secretion GO:0051046 29 0.013
positive regulation of striated muscle contraction GO:0045989 2 0.013
regulation of cellular component movement GO:0051270 62 0.013
cell substrate adhesion GO:0031589 1 0.013
secretion by cell GO:0032940 138 0.013
muscle organ development GO:0007517 26 0.013
negative regulation of cellular component organization GO:0051129 33 0.013
apoptotic cell clearance GO:0043277 111 0.013
excretion GO:0007588 49 0.013
covalent chromatin modification GO:0016569 30 0.013
gastrulation GO:0007369 58 0.013
dephosphorylation GO:0016311 17 0.013
regulation of protein metabolic process GO:0051246 81 0.013
chromatin remodeling GO:0006338 2 0.013
cellular response to chemical stimulus GO:0070887 129 0.012
innate immune response GO:0045087 190 0.012
regulation of cell differentiation GO:0045595 81 0.012
microvillus assembly GO:0030033 1 0.012
negative regulation of apoptotic process GO:0043066 17 0.012
positive regulation of stem cell differentiation GO:2000738 1 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
regulation of cell cycle process GO:0010564 145 0.012
actin filament organization GO:0007015 21 0.012
negative regulation of signal transduction GO:0009968 60 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
phosphorus metabolic process GO:0006793 232 0.012
muscle system process GO:0003012 43 0.011
taxis GO:0042330 128 0.011
cell proliferation GO:0008283 116 0.011
basement membrane organization GO:0071711 3 0.011
spermatogenesis GO:0007283 41 0.011
cell morphogenesis GO:0000902 163 0.011
regulation of neurotransmitter levels GO:0001505 36 0.011
mitotic sister chromatid segregation GO:0000070 38 0.011
sister chromatid segregation GO:0000819 46 0.011
neuron projection development GO:0031175 187 0.011
single fertilization GO:0007338 61 0.011
negative regulation of response to external stimulus GO:0032102 3 0.011
rho protein signal transduction GO:0007266 2 0.011
nucleotide metabolic process GO:0009117 108 0.011
internal peptidyl lysine acetylation GO:0018393 3 0.011
regulation of chromatin modification GO:1903308 2 0.010
cell type specific apoptotic process GO:0097285 4 0.010
regulation of mitotic spindle organization GO:0060236 3 0.010
regulation of multi organism process GO:0043900 69 0.010
regulation of small gtpase mediated signal transduction GO:0051056 41 0.010
cell cycle arrest GO:0007050 6 0.010
establishment of protein localization GO:0045184 50 0.010
defecation GO:0030421 47 0.010
endodermal cell differentiation GO:0035987 18 0.010
regulation of anatomical structure size GO:0090066 46 0.010
regulation of intracellular signal transduction GO:1902531 77 0.010

ttm-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.925
congenital muscular dystrophy DOID:0050557 0 0.925
muscular disease DOID:0080000 0 0.925
muscular dystrophy DOID:9884 0 0.925
disease of anatomical entity DOID:7 0 0.925
musculoskeletal system disease DOID:17 0 0.925
muscle tissue disease DOID:66 0 0.925
heart disease DOID:114 0 0.781
cardiomyopathy DOID:0050700 0 0.781
cardiovascular system disease DOID:1287 0 0.781
progeria DOID:3911 0 0.400
lipodystrophy DOID:811 0 0.349
skin disease DOID:37 0 0.349
integumentary system disease DOID:16 0 0.349
familial partial lipodystrophy DOID:0050440 0 0.349
dilated cardiomyopathy DOID:12930 0 0.295
intrinsic cardiomyopathy DOID:0060036 0 0.295
neuromuscular disease DOID:440 0 0.201
charcot marie tooth disease type 2 DOID:0050539 0 0.201
charcot marie tooth disease DOID:10595 0 0.201
nervous system disease DOID:863 0 0.201
neuropathy DOID:870 0 0.201
emery dreifuss muscular dystrophy DOID:11726 0 0.061
immune system disease DOID:2914 0 0.013
anemia DOID:2355 0 0.013
hematopoietic system disease DOID:74 0 0.013