Caenorhabditis elegans

23 known processes

chk-1 (CELE_Y39H10A.7)

Protein CHK-1

chk-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle organization GO:0006996 783 0.716
embryo development GO:0009790 3052 0.653
post embryonic development GO:0009791 2152 0.643
embryo development ending in birth or egg hatching GO:0009792 2992 0.639
single organism reproductive process GO:0044702 1196 0.556
cell cycle GO:0007049 526 0.554
organ development GO:0048513 1102 0.551
single organism organelle organization GO:1902589 501 0.523
genitalia development GO:0048806 741 0.433
gonad development GO:0008406 840 0.428
meiotic cell cycle GO:0051321 335 0.417
locomotion GO:0040011 1634 0.413
cell cycle process GO:0022402 482 0.382
establishment of localization GO:0051234 1171 0.359
nucleobase containing compound metabolic process GO:0006139 406 0.342
mitotic cell cycle process GO:1903047 194 0.316
development of primary sexual characteristics GO:0045137 840 0.313
negative regulation of biological process GO:0048519 567 0.280
organelle fission GO:0048285 363 0.280
developmental process involved in reproduction GO:0003006 1165 0.273
gamete generation GO:0007276 461 0.272
transport GO:0006810 1093 0.262
sex differentiation GO:0007548 909 0.261
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.260
multicellular organism reproduction GO:0032504 819 0.251
regulation of multicellular organismal process GO:0051239 726 0.243
meiotic cell cycle process GO:1903046 170 0.236
cytoskeleton organization GO:0007010 339 0.232
reproductive structure development GO:0048608 850 0.232
cellular response to stress GO:0033554 162 0.231
biosynthetic process GO:0009058 323 0.227
hermaphrodite genitalia development GO:0040035 734 0.225
single organism localization GO:1902578 518 0.217
nucleic acid metabolic process GO:0090304 299 0.208
regulation of developmental process GO:0050793 684 0.192
sexual reproduction GO:0019953 546 0.184
response to biotic stimulus GO:0009607 101 0.184
multicellular organismal reproductive process GO:0048609 815 0.183
multi organism reproductive process GO:0044703 867 0.183
cellular response to dna damage stimulus GO:0006974 41 0.179
positive regulation of cellular process GO:0048522 332 0.178
cellular localization GO:0051641 360 0.172
meiotic nuclear division GO:0007126 300 0.167
meiotic chromosome segregation GO:0045132 139 0.166
negative regulation of cellular process GO:0048523 239 0.162
anterior posterior axis specification GO:0009948 17 0.160
regulation of nematode larval development GO:0061062 260 0.158
dna metabolic process GO:0006259 74 0.156
vulval development GO:0040025 333 0.149
organic cyclic compound biosynthetic process GO:1901362 195 0.142
reproductive system development GO:0061458 850 0.136
gene expression GO:0010467 412 0.135
macromolecule biosynthetic process GO:0009059 250 0.130
macromolecule catabolic process GO:0009057 202 0.130
oocyte differentiation GO:0009994 45 0.128
chromosome segregation GO:0007059 180 0.127
regulation of cellular metabolic process GO:0031323 305 0.125
post embryonic organ development GO:0048569 336 0.125
protein metabolic process GO:0019538 422 0.125
regulation of vulval development GO:0040028 248 0.123
macromolecular complex subunit organization GO:0043933 320 0.122
death GO:0016265 547 0.121
organic substance biosynthetic process GO:1901576 323 0.121
vesicle mediated transport GO:0016192 852 0.118
regulation of post embryonic development GO:0048580 260 0.116
cellular biosynthetic process GO:0044249 315 0.116
organic substance catabolic process GO:1901575 294 0.115
catabolic process GO:0009056 318 0.112
chromosome organization GO:0051276 104 0.112
regulation of mitotic cell cycle GO:0007346 76 0.110
behavior GO:0007610 527 0.108
oviposition GO:0018991 364 0.108
negative regulation of macromolecule metabolic process GO:0010605 229 0.106
regulation of metabolic process GO:0019222 478 0.104
cellular component biogenesis GO:0044085 297 0.104
protein catabolic process GO:0030163 162 0.104
female gamete generation GO:0007292 254 0.103
multi organism reproductive behavior GO:0044705 387 0.103
cellular component assembly GO:0022607 293 0.102
oogenesis GO:0048477 229 0.100
protein complex subunit organization GO:0071822 280 0.097
positive regulation of gene expression GO:0010628 112 0.096
macromolecule localization GO:0033036 771 0.095
regulation of biological quality GO:0065008 741 0.093
regulation of multicellular organismal development GO:2000026 317 0.091
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.090
regulation of response to stimulus GO:0048583 243 0.089
receptor mediated endocytosis GO:0006898 715 0.089
microtubule based process GO:0007017 182 0.089
cell division GO:0051301 262 0.088
multicellular organismal aging GO:0010259 812 0.087
single organism signaling GO:0044700 401 0.086
multicellular organism growth GO:0035264 385 0.082
germ cell development GO:0007281 351 0.082
oocyte development GO:0048599 44 0.080
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.080
reproductive behavior GO:0019098 387 0.079
cell motility GO:0048870 313 0.079
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.079
neurogenesis GO:0022008 236 0.077
posttranscriptional gene silencing GO:0016441 143 0.077
cell cycle phase transition GO:0044770 19 0.077
cellular catabolic process GO:0044248 199 0.077
aging GO:0007568 812 0.077
multi multicellular organism process GO:0044706 390 0.076
body morphogenesis GO:0010171 620 0.076
regulation of primary metabolic process GO:0080090 292 0.076
protein localization GO:0008104 205 0.075
regulation of transport GO:0051049 91 0.075
organelle assembly GO:0070925 214 0.074
cellular macromolecule biosynthetic process GO:0034645 247 0.073
oocyte construction GO:0007308 2 0.073
regulation of cell cycle process GO:0010564 145 0.073
endocytosis GO:0006897 819 0.072
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.071
phosphate containing compound metabolic process GO:0006796 232 0.069
regulation of nitrogen compound metabolic process GO:0051171 222 0.068
positive regulation of transcription dna templated GO:0045893 102 0.067
determination of adult lifespan GO:0008340 812 0.067
phosphorus metabolic process GO:0006793 232 0.066
female meiotic division GO:0007143 17 0.063
cell development GO:0048468 696 0.063
regulation of macromolecule biosynthetic process GO:0010556 189 0.062
single organism transport GO:0044765 447 0.062
maintenance of location GO:0051235 580 0.060
oocyte axis specification GO:0007309 2 0.060
negative regulation of vulval development GO:0040027 206 0.060
multi organism behavior GO:0051705 389 0.059
negative regulation of post embryonic development GO:0048581 208 0.059
rna metabolic process GO:0016070 228 0.058
regulation of cell cycle GO:0051726 194 0.057
establishment of localization in cell GO:0051649 318 0.057
lipid storage GO:0019915 565 0.056
programmed cell death GO:0012501 500 0.056
positive regulation of cellular metabolic process GO:0031325 178 0.055
response to external stimulus GO:0009605 289 0.055
growth GO:0040007 562 0.054
regulation of biosynthetic process GO:0009889 189 0.054
positive regulation of biosynthetic process GO:0009891 109 0.054
positive regulation of cellular biosynthetic process GO:0031328 109 0.054
cellular protein metabolic process GO:0044267 279 0.053
regulation of macromolecule metabolic process GO:0060255 421 0.052
cell projection assembly GO:0030031 35 0.051
nervous system development GO:0007399 253 0.051
regulation of gene expression GO:0010468 366 0.051
tube development GO:0035295 126 0.050
regulation of cell communication GO:0010646 176 0.050
cell fate commitment GO:0045165 139 0.049
positive regulation of rna metabolic process GO:0051254 103 0.048
cellular macromolecule localization GO:0070727 75 0.048
response to abiotic stimulus GO:0009628 152 0.048
positive regulation of nucleic acid templated transcription GO:1903508 102 0.048
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.046
regulation of multicellular organism growth GO:0040014 373 0.046
regulation of signaling GO:0023051 172 0.046
regulation of developmental growth GO:0048638 389 0.045
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.045
cellular protein modification process GO:0006464 207 0.044
lipid localization GO:0010876 573 0.044
negative regulation of metabolic process GO:0009892 240 0.043
regulation of cell projection assembly GO:0060491 3 0.042
mitotic nuclear division GO:0007067 89 0.042
regulation of cellular component organization GO:0051128 248 0.042
heterocycle biosynthetic process GO:0018130 187 0.042
negative regulation of nematode larval development GO:0061064 208 0.042
posttranscriptional regulation of gene expression GO:0010608 166 0.042
multicellular organismal reproductive behavior GO:0033057 384 0.041
generation of neurons GO:0048699 235 0.041
cell migration GO:0016477 306 0.041
cellular component assembly involved in morphogenesis GO:0010927 183 0.041
signal transduction GO:0007165 317 0.040
tissue development GO:0009888 112 0.040
positive regulation of macromolecule metabolic process GO:0010604 149 0.039
organic cyclic compound catabolic process GO:1901361 119 0.038
cellular nitrogen compound biosynthetic process GO:0044271 192 0.038
anterior posterior pattern specification GO:0009952 27 0.038
positive regulation of metabolic process GO:0009893 187 0.038
regulation of cellular biosynthetic process GO:0031326 189 0.038
negative regulation of cell cycle GO:0045786 53 0.038
macromolecule modification GO:0043412 218 0.037
head development GO:0060322 1 0.037
cellular nitrogen compound catabolic process GO:0044270 119 0.037
actin cytoskeleton organization GO:0030036 184 0.037
regulation of gene expression epigenetic GO:0040029 163 0.037
gene silencing GO:0016458 143 0.036
organ morphogenesis GO:0009887 67 0.036
spindle organization GO:0007051 92 0.036
small molecule metabolic process GO:0044281 186 0.036
gene silencing by rna GO:0031047 143 0.036
negative regulation of gene expression GO:0010629 217 0.036
molting cycle GO:0042303 281 0.036
developmental growth GO:0048589 412 0.036
response to other organism GO:0051707 101 0.035
protein modification process GO:0036211 207 0.035
regulation of meiotic cell cycle GO:0051445 136 0.035
nucleotide metabolic process GO:0009117 108 0.035
cellular component movement GO:0006928 388 0.035
macromolecular complex assembly GO:0065003 193 0.034
protein complex biogenesis GO:0070271 186 0.034
posttranscriptional gene silencing by rna GO:0035194 143 0.034
positive regulation of cell cycle GO:0045787 55 0.034
innate immune response GO:0045087 190 0.034
negative regulation of response to stimulus GO:0048585 73 0.033
response to external biotic stimulus GO:0043207 101 0.033
protein complex assembly GO:0006461 186 0.033
system process GO:0003008 136 0.033
regulation of protein localization GO:0032880 50 0.033
cell proliferation GO:0008283 116 0.032
nucleobase containing compound catabolic process GO:0034655 114 0.032
cellular response to organic substance GO:0071310 119 0.032
dna geometric change GO:0032392 3 0.032
positive regulation of multicellular organismal process GO:0051240 417 0.032
membrane organization GO:0061024 135 0.032
regulation of response to stress GO:0080134 28 0.032
neuron differentiation GO:0030182 217 0.032
regulation of localization GO:0032879 194 0.031
cytokinesis GO:0000910 80 0.031
regulation of organelle organization GO:0033043 164 0.031
cellular component morphogenesis GO:0032989 318 0.031
response to chemical GO:0042221 356 0.030
intracellular signal transduction GO:0035556 96 0.030
cell surface receptor signaling pathway GO:0007166 149 0.030
regulation of molecular function GO:0065009 89 0.030
regulation of growth GO:0040008 409 0.030
actin filament based process GO:0030029 191 0.030
positive regulation of growth GO:0045927 369 0.030
nucleic acid templated transcription GO:0097659 169 0.029
cellular macromolecular complex assembly GO:0034622 184 0.029
single organism biosynthetic process GO:0044711 91 0.029
cell death GO:0008219 547 0.029
cellular response to abiotic stimulus GO:0071214 4 0.029
organic substance transport GO:0071702 113 0.028
organonitrogen compound catabolic process GO:1901565 90 0.028
muscle structure development GO:0061061 191 0.028
establishment of nucleus localization GO:0040023 55 0.027
rna localization GO:0006403 3 0.027
developmental maturation GO:0021700 26 0.027
establishment of organelle localization GO:0051656 123 0.027
single organism cellular localization GO:1902580 72 0.027
regulation of transcription dna templated GO:0006355 164 0.027
defense response GO:0006952 296 0.026
regulation of organ morphogenesis GO:2000027 4 0.026
heterocycle catabolic process GO:0046700 119 0.025
striated muscle cell differentiation GO:0051146 158 0.025
cellular macromolecule catabolic process GO:0044265 73 0.024
regulation of cell division GO:0051302 142 0.024
positive regulation of developmental process GO:0051094 408 0.024
positive regulation of multicellular organism growth GO:0040018 352 0.024
negative regulation of multicellular organismal process GO:0051241 236 0.024
negative regulation of developmental process GO:0051093 227 0.024
spermatogenesis GO:0007283 41 0.024
cell projection organization GO:0030030 231 0.024
regulation of signal transduction GO:0009966 135 0.023
response to wounding GO:0009611 4 0.023
epithelial tube morphogenesis GO:0060562 1 0.023
signaling GO:0023052 401 0.023
positive regulation of rna biosynthetic process GO:1902680 102 0.023
immune response GO:0006955 192 0.023
regulation of cell differentiation GO:0045595 81 0.023
actomyosin structure organization GO:0031032 154 0.023
apoptotic cell clearance GO:0043277 111 0.022
regulation of rna biosynthetic process GO:2001141 165 0.022
phosphorylation GO:0016310 116 0.022
anatomical structure formation involved in morphogenesis GO:0048646 250 0.022
engulfment of apoptotic cell GO:0043652 94 0.022
regulation of nucleocytoplasmic transport GO:0046822 3 0.022
pattern specification process GO:0007389 59 0.022
mitotic sister chromatid segregation GO:0000070 38 0.022
regulation of protein metabolic process GO:0051246 81 0.022
regulation of cell proliferation GO:0042127 105 0.022
regulation of rna metabolic process GO:0051252 173 0.022
sensory organ morphogenesis GO:0090596 2 0.021
cytoskeleton dependent cytokinesis GO:0061640 35 0.021
defense response to other organism GO:0098542 100 0.021
secretion GO:0046903 147 0.020
cell morphogenesis involved in differentiation GO:0000904 112 0.020
fertilization GO:0009566 63 0.020
purine nucleotide catabolic process GO:0006195 75 0.020
muscle tissue development GO:0060537 1 0.020
cell maturation GO:0048469 26 0.020
positive regulation of cell communication GO:0010647 69 0.020
aromatic compound biosynthetic process GO:0019438 192 0.019
regulation of cell death GO:0010941 65 0.019
localization of cell GO:0051674 313 0.019
male gamete generation GO:0048232 41 0.019
response to organic substance GO:0010033 131 0.019
chemical homeostasis GO:0048878 29 0.019
defense response to bacterium GO:0042742 86 0.019
transcription dna templated GO:0006351 168 0.019
carbohydrate derivative metabolic process GO:1901135 141 0.018
positive regulation of developmental growth GO:0048639 354 0.018
cell type specific apoptotic process GO:0097285 4 0.018
dna replication GO:0006260 15 0.018
purine nucleoside triphosphate catabolic process GO:0009146 72 0.018
cellular protein localization GO:0034613 75 0.018
regulation of nucleic acid templated transcription GO:1903506 165 0.018
purine ribonucleotide metabolic process GO:0009150 95 0.018
dauer larval development GO:0040024 92 0.018
nucleus organization GO:0006997 38 0.017
cellular protein complex assembly GO:0043623 178 0.017
rna interference GO:0016246 137 0.017
cell cell signaling GO:0007267 118 0.017
striated muscle cell development GO:0055002 157 0.017
regulation of epithelial cell proliferation GO:0050678 1 0.017
response to bacterium GO:0009617 86 0.017
purine ribonucleotide catabolic process GO:0009154 75 0.017
ribonucleotide metabolic process GO:0009259 99 0.017
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.017
pronuclear migration GO:0035046 51 0.017
regulation of cytoskeleton organization GO:0051493 41 0.017
secretion by cell GO:0032940 138 0.017
apoptotic process GO:0006915 478 0.017
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 9 0.017
aromatic compound catabolic process GO:0019439 116 0.016
regulation of catalytic activity GO:0050790 78 0.016
muscle organ development GO:0007517 26 0.016
negative regulation of cell communication GO:0010648 61 0.016
microtubule polymerization or depolymerization GO:0031109 22 0.016
embryonic morphogenesis GO:0048598 152 0.016
positive regulation of protein transport GO:0051222 4 0.016
phagocytosis GO:0006909 115 0.016
glycosyl compound catabolic process GO:1901658 79 0.016
regulation of multi organism process GO:0043900 69 0.016
muscle cell development GO:0055001 158 0.016
chromatin organization GO:0006325 32 0.016
skeletal muscle organ development GO:0060538 3 0.016
epithelium development GO:0060429 68 0.016
organonitrogen compound metabolic process GO:1901564 151 0.016
axis specification GO:0009798 23 0.015
phagocytosis engulfment GO:0006911 98 0.015
ribonucleotide catabolic process GO:0009261 75 0.015
neuron projection guidance GO:0097485 82 0.015
single organism catabolic process GO:0044712 129 0.015
homeostatic process GO:0042592 51 0.015
mitotic spindle organization GO:0007052 81 0.015
taxis GO:0042330 128 0.015
negative regulation of cellular metabolic process GO:0031324 95 0.015
rrna processing GO:0006364 3 0.015
mitotic g2 m transition checkpoint GO:0044818 1 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.015
organophosphate metabolic process GO:0019637 125 0.015
regulation of cytoplasmic transport GO:1903649 3 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
protein oligomerization GO:0051259 4 0.014
intracellular transport GO:0046907 77 0.014
regulation of meiosis GO:0040020 94 0.014
regulation of cellular localization GO:0060341 42 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
pigment metabolic process GO:0042440 2 0.014
filopodium assembly GO:0046847 2 0.014
rna biosynthetic process GO:0032774 169 0.014
negative regulation of mitotic cell cycle GO:0045930 42 0.014
ribonucleoside monophosphate metabolic process GO:0009161 45 0.014
negative regulation of cell cycle process GO:0010948 12 0.014
detection of external stimulus GO:0009581 4 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.013
nucleoside phosphate metabolic process GO:0006753 108 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
meiosis i GO:0007127 19 0.013
g1 s transition of mitotic cell cycle GO:0000082 2 0.013
embryonic axis specification GO:0000578 9 0.013
negative regulation of biosynthetic process GO:0009890 65 0.013
organelle localization GO:0051640 127 0.013
dna recombination GO:0006310 19 0.013
nucleus localization GO:0051647 55 0.013
regulation of nuclear division GO:0051783 115 0.013
myofibril assembly GO:0030239 154 0.013
regionalization GO:0003002 31 0.013
negative regulation of signaling GO:0023057 61 0.013
regulation of cellular protein metabolic process GO:0032268 75 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
enzyme linked receptor protein signaling pathway GO:0007167 50 0.012
myosin filament organization GO:0031033 138 0.012
cell cycle dna replication GO:0044786 3 0.012
nucleobase containing compound biosynthetic process GO:0034654 184 0.012
digestive system development GO:0055123 122 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.012
establishment of spindle localization GO:0051293 51 0.012
positive regulation of intracellular transport GO:0032388 2 0.012
purine nucleotide metabolic process GO:0006163 95 0.012
male anatomical structure morphogenesis GO:0090598 78 0.012
epithelial cell proliferation GO:0050673 1 0.012
negative regulation of signal transduction GO:0009968 60 0.012
purine containing compound metabolic process GO:0072521 95 0.012
regulation of embryonic development GO:0045995 16 0.012
ribose phosphate metabolic process GO:0019693 99 0.012
sister chromatid segregation GO:0000819 46 0.012
mitotic cell cycle phase transition GO:0044772 13 0.012
tripartite regional subdivision GO:0007351 7 0.011
cellular response to chemical stimulus GO:0070887 129 0.011
pole plasm assembly GO:0007315 2 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
single organism behavior GO:0044708 83 0.011
axon guidance GO:0007411 82 0.011
regulation of phosphate metabolic process GO:0019220 81 0.011
digestive tract development GO:0048565 122 0.011
muscle cell differentiation GO:0042692 171 0.011
tissue morphogenesis GO:0048729 65 0.011
inactivation of mapkkk activity GO:0051390 2 0.011
double strand break repair GO:0006302 5 0.011
cell matrix adhesion GO:0007160 1 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.011
cell cycle g1 s phase transition GO:0044843 2 0.011
ribonucleoside metabolic process GO:0009119 98 0.011
myosin filament assembly GO:0031034 138 0.011
germ line sex determination GO:0018992 51 0.011
detection of abiotic stimulus GO:0009582 4 0.011
neuron development GO:0048666 199 0.011
regulation of cell fate commitment GO:0010453 22 0.010
regulation of programmed cell death GO:0043067 50 0.010
positive regulation of vulval development GO:0040026 52 0.010
regulation of lipid metabolic process GO:0019216 4 0.010
regulation of intracellular signal transduction GO:1902531 77 0.010
regulation of phosphorus metabolic process GO:0051174 81 0.010
male sex differentiation GO:0046661 86 0.010
sex determination GO:0007530 60 0.010

chk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030