Caenorhabditis elegans

78 known processes

him-6 (CELE_T04A11.6)

Protein HIM-6

him-6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 300 0.765
embryo development GO:0009790 3052 0.488
organelle fission GO:0048285 363 0.455
genitalia development GO:0048806 741 0.454
organ development GO:0048513 1102 0.434
Mouse
chromosome segregation GO:0007059 180 0.433
meiotic chromosome segregation GO:0045132 139 0.427
meiotic cell cycle GO:0051321 335 0.318
organelle organization GO:0006996 783 0.314
regulation of macromolecule metabolic process GO:0060255 421 0.306
Human Mouse Fly
development of primary sexual characteristics GO:0045137 840 0.298
single organism reproductive process GO:0044702 1196 0.255
gamete generation GO:0007276 461 0.255
embryo development ending in birth or egg hatching GO:0009792 2992 0.241
reproductive system development GO:0061458 850 0.231
meiotic cell cycle process GO:1903046 170 0.215
reproductive structure development GO:0048608 850 0.212
vesicle mediated transport GO:0016192 852 0.204
multi organism reproductive process GO:0044703 867 0.196
cellular localization GO:0051641 360 0.196
hermaphrodite genitalia development GO:0040035 734 0.195
cell cycle GO:0007049 526 0.185
cell cycle process GO:0022402 482 0.182
regulation of cellular metabolic process GO:0031323 305 0.158
Human Mouse Fly
death GO:0016265 547 0.150
organelle assembly GO:0070925 214 0.147
regulation of metabolic process GO:0019222 478 0.145
Human Mouse Fly
gonad development GO:0008406 840 0.142
developmental process involved in reproduction GO:0003006 1165 0.141
cell development GO:0048468 696 0.141
gene expression GO:0010467 412 0.139
Human
programmed cell death GO:0012501 500 0.138
apoptotic process GO:0006915 478 0.136
transport GO:0006810 1093 0.127
post embryonic organ development GO:0048569 336 0.124
multicellular organism reproduction GO:0032504 819 0.122
positive regulation of developmental process GO:0051094 408 0.121
single organism transport GO:0044765 447 0.117
post embryonic development GO:0009791 2152 0.111
multicellular organismal reproductive process GO:0048609 815 0.109
single organism localization GO:1902578 518 0.108
sex differentiation GO:0007548 909 0.104
regulation of cell cycle process GO:0010564 145 0.100
Human
regulation of developmental process GO:0050793 684 0.098
macromolecule localization GO:0033036 771 0.095
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.092
anatomical structure formation involved in morphogenesis GO:0048646 250 0.088
receptor mediated endocytosis GO:0006898 715 0.088
multicellular organismal reproductive behavior GO:0033057 384 0.088
organic cyclic compound biosynthetic process GO:1901362 195 0.084
Human Fly
establishment of localization in cell GO:0051649 318 0.083
nucleobase containing compound metabolic process GO:0006139 406 0.081
regulation of growth GO:0040008 409 0.081
single organism intracellular transport GO:1902582 70 0.078
cellular component assembly GO:0022607 293 0.076
Human
aging GO:0007568 812 0.074
lipid localization GO:0010876 573 0.074
single organism organelle organization GO:1902589 501 0.074
cell death GO:0008219 547 0.074
oviposition GO:0018991 364 0.072
vulval development GO:0040025 333 0.071
cellular component biogenesis GO:0044085 297 0.070
Human
regulation of multicellular organismal development GO:2000026 317 0.069
negative regulation of post embryonic development GO:0048581 208 0.069
body morphogenesis GO:0010171 620 0.068
regulation of biological quality GO:0065008 741 0.067
Mouse
germ cell development GO:0007281 351 0.067
negative regulation of biological process GO:0048519 567 0.067
regulation of macromolecule biosynthetic process GO:0010556 189 0.064
Human
nucleic acid metabolic process GO:0090304 299 0.061
lipid storage GO:0019915 565 0.061
regulation of multicellular organismal process GO:0051239 726 0.061
negative regulation of nematode larval development GO:0061064 208 0.059
maintenance of location GO:0051235 580 0.059
macromolecule biosynthetic process GO:0009059 250 0.059
Human Fly
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.058
Human
regulation of cellular component organization GO:0051128 248 0.057
multi multicellular organism process GO:0044706 390 0.057
positive regulation of growth GO:0045927 369 0.056
multicellular organismal aging GO:0010259 812 0.056
behavior GO:0007610 527 0.056
cell division GO:0051301 262 0.055
Human
sexual reproduction GO:0019953 546 0.055
regulation of nitrogen compound metabolic process GO:0051171 222 0.055
Human Mouse Fly
female gamete generation GO:0007292 254 0.053
regulation of nematode larval development GO:0061062 260 0.053
protein complex subunit organization GO:0071822 280 0.051
Human
positive regulation of developmental growth GO:0048639 354 0.050
regulation of organelle organization GO:0033043 164 0.050
multi organism reproductive behavior GO:0044705 387 0.050
positive regulation of cellular process GO:0048522 332 0.049
Human Mouse
macromolecular complex subunit organization GO:0043933 320 0.049
Human
biosynthetic process GO:0009058 323 0.049
Human Fly
signaling GO:0023052 401 0.049
cellular component movement GO:0006928 388 0.049
positive regulation of multicellular organismal process GO:0051240 417 0.046
cellular component morphogenesis GO:0032989 318 0.046
regulation of multicellular organism growth GO:0040014 373 0.046
neuromuscular junction development GO:0007528 2 0.045
growth GO:0040007 562 0.045
organic substance biosynthetic process GO:1901576 323 0.045
Human Fly
determination of adult lifespan GO:0008340 812 0.045
locomotion GO:0040011 1634 0.044
positive regulation of multicellular organism growth GO:0040018 352 0.043
head development GO:0060322 1 0.043
macromolecular complex assembly GO:0065003 193 0.043
Human
developmental growth GO:0048589 412 0.042
positive regulation of metabolic process GO:0009893 187 0.042
Human
negative regulation of developmental process GO:0051093 227 0.042
cellular macromolecule localization GO:0070727 75 0.042
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.041
regulation of post embryonic development GO:0048580 260 0.041
multi organism behavior GO:0051705 389 0.041
establishment of localization GO:0051234 1171 0.040
cytoskeleton organization GO:0007010 339 0.040
reproductive behavior GO:0019098 387 0.040
single organism signaling GO:0044700 401 0.040
negative regulation of multicellular organismal process GO:0051241 236 0.039
cellular macromolecule biosynthetic process GO:0034645 247 0.039
Human Fly
negative regulation of cellular process GO:0048523 239 0.038
positive regulation of neurogenesis GO:0050769 4 0.037
regulation of developmental growth GO:0048638 389 0.037
dna repair GO:0006281 23 0.034
Human Mouse Fly
single organism cellular localization GO:1902580 72 0.034
oogenesis GO:0048477 229 0.030
protein complex biogenesis GO:0070271 186 0.030
Human
transcription from rna polymerase ii promoter GO:0006366 149 0.030
intracellular transport GO:0046907 77 0.029
positive regulation of gene expression GO:0010628 112 0.029
Human
response to chemical GO:0042221 356 0.028
Human
negative regulation of macromolecule metabolic process GO:0010605 229 0.027
Human Mouse Fly
heterocycle biosynthetic process GO:0018130 187 0.027
Human Fly
regulation of cellular biosynthetic process GO:0031326 189 0.026
Human
cellular biosynthetic process GO:0044249 315 0.026
Human Fly
endocytosis GO:0006897 819 0.026
regulation of gene expression GO:0010468 366 0.025
Human
regulation of cell communication GO:0010646 176 0.025
long term memory GO:0007616 2 0.025
single organism behavior GO:0044708 83 0.025
microtubule based process GO:0007017 182 0.025
muscle structure development GO:0061061 191 0.023
aromatic compound biosynthetic process GO:0019438 192 0.023
Human Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.023
Human Fly
mitotic cell cycle process GO:1903047 194 0.022
cellular protein localization GO:0034613 75 0.022
negative regulation of vulval development GO:0040027 206 0.022
response to external stimulus GO:0009605 289 0.022
synaptic growth at neuromuscular junction GO:0051124 1 0.020
protein localization GO:0008104 205 0.020
small molecule metabolic process GO:0044281 186 0.020
Human Mouse Fly
regulation of primary metabolic process GO:0080090 292 0.019
Human Mouse Fly
cellular response to stress GO:0033554 162 0.019
protein complex assembly GO:0006461 186 0.019
Human
multicellular organism growth GO:0035264 385 0.019
positive regulation of cellular biosynthetic process GO:0031328 109 0.019
Human
synaptic transmission GO:0007268 106 0.019
macromolecule modification GO:0043412 218 0.019
Human
positive regulation of phosphorus metabolic process GO:0010562 56 0.018
signal transduction GO:0007165 317 0.018
cellular amine metabolic process GO:0044106 15 0.018
polar body extrusion after meiotic divisions GO:0040038 14 0.017
cell projection organization GO:0030030 231 0.017
adult behavior GO:0030534 3 0.017
posttranscriptional gene silencing GO:0016441 143 0.016
chemotaxis GO:0006935 120 0.016
cellular macromolecular complex assembly GO:0034622 184 0.016
regulation of apoptotic process GO:0042981 36 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.016
Human
cellular response to chemical stimulus GO:0070887 129 0.016
Human
actin filament based process GO:0030029 191 0.016
regulation of cell cycle GO:0051726 194 0.016
Human
response to abiotic stimulus GO:0009628 152 0.016
cell morphogenesis GO:0000902 163 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
Human Mouse Fly
synapsis GO:0007129 10 0.016
positive regulation of phosphate metabolic process GO:0045937 56 0.016
establishment of organelle localization GO:0051656 123 0.016
apoptotic cell clearance GO:0043277 111 0.015
striated muscle cell differentiation GO:0051146 158 0.015
mitotic nuclear division GO:0007067 89 0.015
myosin filament assembly GO:0031034 138 0.015
regulation of phosphorylation GO:0042325 45 0.015
Human
rna processing GO:0006396 34 0.015
organic acid metabolic process GO:0006082 47 0.015
regulation of signaling GO:0023051 172 0.015
memory GO:0007613 3 0.015
tissue development GO:0009888 112 0.015
cell recognition GO:0008037 85 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
neuron differentiation GO:0030182 217 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
regulation of meiosis GO:0040020 94 0.014
nucleic acid templated transcription GO:0097659 169 0.014
Human
rna biosynthetic process GO:0032774 169 0.014
Human
neurological system process GO:0050877 53 0.014
membrane invagination GO:0010324 98 0.014
amine metabolic process GO:0009308 15 0.014
regulation of programmed cell death GO:0043067 50 0.014
cell proliferation GO:0008283 116 0.014
Mouse
cellular amino acid metabolic process GO:0006520 15 0.014
gene silencing GO:0016458 143 0.014
positive regulation of macromolecule metabolic process GO:0010604 149 0.013
Human
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.013
Human
germ line sex determination GO:0018992 51 0.013
positive regulation of cell projection organization GO:0031346 4 0.013
muscle cell differentiation GO:0042692 171 0.013
dna recombination GO:0006310 19 0.013
regulation of nuclear division GO:0051783 115 0.013
regulation of molecular function GO:0065009 89 0.013
Human Mouse
sensory organ morphogenesis GO:0090596 2 0.013
rna polyadenylation GO:0043631 3 0.013
protein localization to organelle GO:0033365 37 0.012
defense response GO:0006952 296 0.012
rna localization GO:0006403 3 0.012
cell migration GO:0016477 306 0.012
intracellular signal transduction GO:0035556 96 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
chromosome organization involved in meiosis GO:0070192 25 0.012
catabolic process GO:0009056 318 0.012
Human Mouse Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
cell cell signaling GO:0007267 118 0.012
regulation of vulval development GO:0040028 248 0.012
ion transport GO:0006811 113 0.012
positive regulation of gtpase activity GO:0043547 28 0.012
regulation of cell death GO:0010941 65 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
dna metabolic process GO:0006259 74 0.012
actomyosin structure organization GO:0031032 154 0.011
organelle localization GO:0051640 127 0.011
canonical wnt signaling pathway GO:0060070 3 0.011
cellular protein modification process GO:0006464 207 0.011
Human
meiosis i GO:0007127 19 0.011
neuron projection development GO:0031175 187 0.011
rna interference GO:0016246 137 0.011
cell part morphogenesis GO:0032990 152 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
synapse organization GO:0050808 24 0.011
cellular ketone metabolic process GO:0042180 14 0.011
cellular component assembly involved in morphogenesis GO:0010927 183 0.011
establishment of protein localization GO:0045184 50 0.011
regulation of meiotic cell cycle GO:0051445 136 0.011
response to nutrient levels GO:0031667 35 0.010
adult locomotory behavior GO:0008344 1 0.010
regulation of cell proliferation GO:0042127 105 0.010
Mouse
axonal fasciculation GO:0007413 79 0.010
protein metabolic process GO:0019538 422 0.010
Human
cellular protein complex assembly GO:0043623 178 0.010
actin cytoskeleton organization GO:0030036 184 0.010
regulation of dna metabolic process GO:0051052 14 0.010
Human Mouse Fly
neuron development GO:0048666 199 0.010
regulation of apoptotic signaling pathway GO:2001233 1 0.010
cell projection morphogenesis GO:0048858 148 0.010
positive regulation of transcription dna templated GO:0045893 102 0.010
Human

him-6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.055
cancer DOID:162 0 0.028
organ system cancer DOID:0050686 0 0.028
large intestine cancer DOID:5672 0 0.018
gastrointestinal system cancer DOID:3119 0 0.018
intestinal cancer DOID:10155 0 0.018