Caenorhabditis elegans

67 known processes

lin-40 (CELE_T27C4.4)

Protein LIN-40

lin-40 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.737
vulval development GO:0040025 333 0.684
organ development GO:0048513 1102 0.635
positive regulation of nematode larval development GO:0061063 54 0.622
embryo development ending in birth or egg hatching GO:0009792 2992 0.575
reproductive system development GO:0061458 850 0.554
regulation of nematode larval development GO:0061062 260 0.523
positive regulation of vulval development GO:0040026 52 0.514
locomotion GO:0040011 1634 0.508
sex differentiation GO:0007548 909 0.508
regulation of developmental process GO:0050793 684 0.503
establishment of localization GO:0051234 1171 0.491
single organism reproductive process GO:0044702 1196 0.486
embryo development GO:0009790 3052 0.481
regulation of gene expression GO:0010468 366 0.473
Human Mouse
gonad development GO:0008406 840 0.429
genitalia development GO:0048806 741 0.401
regulation of rna biosynthetic process GO:2001141 165 0.381
Human Mouse
hermaphrodite genitalia development GO:0040035 734 0.377
development of primary sexual characteristics GO:0045137 840 0.367
oviposition GO:0018991 364 0.349
multi organism reproductive process GO:0044703 867 0.347
cell fate commitment GO:0045165 139 0.345
Worm
developmental process involved in reproduction GO:0003006 1165 0.339
regulation of vulval development GO:0040028 248 0.329
multicellular organism reproduction GO:0032504 819 0.315
negative regulation of biological process GO:0048519 567 0.302
regulation of rna metabolic process GO:0051252 173 0.299
Human Mouse
reproductive structure development GO:0048608 850 0.294
gamete generation GO:0007276 461 0.291
cell development GO:0048468 696 0.287
sexual reproduction GO:0019953 546 0.287
cellular component morphogenesis GO:0032989 318 0.282
single organism organelle organization GO:1902589 501 0.281
Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.271
rna biosynthetic process GO:0032774 169 0.270
Human Mouse
receptor mediated endocytosis GO:0006898 715 0.269
negative regulation of gene expression GO:0010629 217 0.263
Mouse
regulation of multicellular organismal process GO:0051239 726 0.261
transcription from rna polymerase ii promoter GO:0006366 149 0.243
Mouse
germ cell development GO:0007281 351 0.239
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.238
Mouse
regulation of cellular metabolic process GO:0031323 305 0.238
Human Mouse
regulation of growth GO:0040008 409 0.237
regulation of transcription dna templated GO:0006355 164 0.234
Mouse
body morphogenesis GO:0010171 620 0.232
tube morphogenesis GO:0035239 79 0.228
meiotic nuclear division GO:0007126 300 0.228
multicellular organismal reproductive process GO:0048609 815 0.221
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.217
Mouse
nucleic acid templated transcription GO:0097659 169 0.215
Human Mouse
multi organism behavior GO:0051705 389 0.212
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.202
negative regulation of nematode larval development GO:0061064 208 0.191
digestive tract morphogenesis GO:0048546 76 0.188
nucleic acid metabolic process GO:0090304 299 0.182
Human Mouse
vesicle mediated transport GO:0016192 852 0.178
macromolecular complex subunit organization GO:0043933 320 0.171
Mouse
negative regulation of macromolecule metabolic process GO:0010605 229 0.170
Human Mouse
biosynthetic process GO:0009058 323 0.169
Human Mouse
heterocycle biosynthetic process GO:0018130 187 0.166
Human Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.166
Human Mouse
endocytosis GO:0006897 819 0.163
cellular macromolecule biosynthetic process GO:0034645 247 0.162
Mouse
nucleobase containing compound metabolic process GO:0006139 406 0.160
Human Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.159
positive regulation of transcription dna templated GO:0045893 102 0.156
Mouse
taxis GO:0042330 128 0.155
organic cyclic compound biosynthetic process GO:1901362 195 0.154
Human Mouse
multicellular organism growth GO:0035264 385 0.153
transport GO:0006810 1093 0.151
transcription dna templated GO:0006351 168 0.151
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.150
Human Mouse
growth GO:0040007 562 0.150
organic substance biosynthetic process GO:1901576 323 0.150
Human Mouse
regulation of nitrogen compound metabolic process GO:0051171 222 0.150
Human Mouse
aging GO:0007568 812 0.149
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.149
Mouse
cell morphogenesis GO:0000902 163 0.149
positive regulation of growth GO:0045927 369 0.148
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.145
Human Mouse
negative regulation of vulval development GO:0040027 206 0.144
multi organism reproductive behavior GO:0044705 387 0.144
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.143
Mouse
reproductive behavior GO:0019098 387 0.142
cell projection morphogenesis GO:0048858 148 0.140
post embryonic organ development GO:0048569 336 0.138
signal transduction GO:0007165 317 0.138
Worm
regulation of metabolic process GO:0019222 478 0.135
Human Mouse
regulation of biosynthetic process GO:0009889 189 0.135
Human Mouse
meiotic cell cycle GO:0051321 335 0.135
positive regulation of developmental process GO:0051094 408 0.134
organ morphogenesis GO:0009887 67 0.133
positive regulation of macromolecule metabolic process GO:0010604 149 0.132
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.130
Human Mouse
protein complex subunit organization GO:0071822 280 0.130
positive regulation of cellular process GO:0048522 332 0.130
Human Mouse
axon guidance GO:0007411 82 0.128
negative regulation of transcription dna templated GO:0045892 53 0.127
Mouse
cellular component assembly GO:0022607 293 0.126
Worm
regulation of multicellular organismal development GO:2000026 317 0.126
positive regulation of multicellular organismal process GO:0051240 417 0.126
regulation of gene expression epigenetic GO:0040029 163 0.124
Human Mouse
single organism signaling GO:0044700 401 0.124
Worm
regulation of cellular biosynthetic process GO:0031326 189 0.123
Human Mouse
organelle organization GO:0006996 783 0.119
Mouse
negative regulation of cellular process GO:0048523 239 0.119
Human Mouse
cell projection organization GO:0030030 231 0.118
regulation of primary metabolic process GO:0080090 292 0.118
Human Mouse
axonogenesis GO:0007409 102 0.113
aromatic compound biosynthetic process GO:0019438 192 0.112
Human Mouse
macromolecule localization GO:0033036 771 0.111
digestive system development GO:0055123 122 0.110
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.109
axon development GO:0061564 163 0.108
regulation of multicellular organism growth GO:0040014 373 0.106
purine containing compound metabolic process GO:0072521 95 0.105
chemotaxis GO:0006935 120 0.104
organelle fission GO:0048285 363 0.103
developmental growth GO:0048589 412 0.102
Zebrafish
cell migration GO:0016477 306 0.102
Worm
cell cycle process GO:0022402 482 0.101
determination of adult lifespan GO:0008340 812 0.101
cell death GO:0008219 547 0.101
cellular response to stress GO:0033554 162 0.100
Human Mouse
female gamete generation GO:0007292 254 0.100
regulation of biological quality GO:0065008 741 0.099
digestive tract development GO:0048565 122 0.098
negative regulation of metabolic process GO:0009892 240 0.097
Human Mouse
multicellular organismal aging GO:0010259 812 0.097
head development GO:0060322 1 0.096
protein complex assembly GO:0006461 186 0.096
molting cycle GO:0042303 281 0.096
signaling GO:0023052 401 0.095
Worm
positive regulation of cellular biosynthetic process GO:0031328 109 0.094
Mouse
neuron projection development GO:0031175 187 0.094
regulation of nucleic acid templated transcription GO:1903506 165 0.093
Human Mouse
regulation of cellular component organization GO:0051128 248 0.093
cellular nitrogen compound biosynthetic process GO:0044271 192 0.092
Human Mouse
cellular localization GO:0051641 360 0.092
organelle localization GO:0051640 127 0.090
mitotic cell cycle process GO:1903047 194 0.090
positive regulation of developmental growth GO:0048639 354 0.090
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.089
Human Mouse
rna metabolic process GO:0016070 228 0.087
Human Mouse
regulation of developmental growth GO:0048638 389 0.087
neuron differentiation GO:0030182 217 0.086
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.085
Mouse
cell division GO:0051301 262 0.085
Worm
lipid localization GO:0010876 573 0.085
negative regulation of post embryonic development GO:0048581 208 0.084
positive regulation of multicellular organism growth GO:0040018 352 0.082
negative regulation of multicellular organismal process GO:0051241 236 0.079
cell cycle GO:0007049 526 0.079
posttranscriptional regulation of gene expression GO:0010608 166 0.079
purine ribonucleotide metabolic process GO:0009150 95 0.078
positive regulation of post embryonic development GO:0048582 54 0.077
single organism localization GO:1902578 518 0.076
cellular component biogenesis GO:0044085 297 0.076
Worm
neuron projection morphogenesis GO:0048812 114 0.076
behavior GO:0007610 527 0.075
nervous system development GO:0007399 253 0.075
cellular biosynthetic process GO:0044249 315 0.075
Human Mouse
negative regulation of developmental process GO:0051093 227 0.074
neuron development GO:0048666 199 0.074
pattern specification process GO:0007389 59 0.073
positive regulation of metabolic process GO:0009893 187 0.073
Human Mouse
neurogenesis GO:0022008 236 0.072
tube development GO:0035295 126 0.072
muscle cell differentiation GO:0042692 171 0.071
sensory organ morphogenesis GO:0090596 2 0.069
lipid storage GO:0019915 565 0.069
male sex differentiation GO:0046661 86 0.069
Worm
positive regulation of rna biosynthetic process GO:1902680 102 0.068
Mouse
neuron projection guidance GO:0097485 82 0.067
maintenance of location GO:0051235 580 0.067
regulation of post embryonic development GO:0048580 260 0.066
positive regulation of gene expression GO:0010628 112 0.065
Mouse
cell part morphogenesis GO:0032990 152 0.065
single organism transport GO:0044765 447 0.065
dna metabolic process GO:0006259 74 0.064
Human Mouse
cellular catabolic process GO:0044248 199 0.062
Human
cell morphogenesis involved in differentiation GO:0000904 112 0.061
macromolecule biosynthetic process GO:0009059 250 0.060
Human Mouse
catabolic process GO:0009056 318 0.060
Human Worm
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.059
Mouse
gene expression GO:0010467 412 0.058
Human Mouse
embryonic morphogenesis GO:0048598 152 0.058
regulation of cell communication GO:0010646 176 0.057
response to chemical GO:0042221 356 0.057
Mouse
cellular protein metabolic process GO:0044267 279 0.055
Human Mouse
cytoskeleton organization GO:0007010 339 0.055
regulation of signaling GO:0023051 172 0.054
ribonucleoside triphosphate metabolic process GO:0009199 87 0.054
macromolecular complex assembly GO:0065003 193 0.054
establishment of organelle localization GO:0051656 123 0.053
regeneration GO:0031099 4 0.052
Zebrafish
response to wounding GO:0009611 4 0.052
Zebrafish Mouse
meiotic cell cycle process GO:1903046 170 0.052
negative regulation of cellular metabolic process GO:0031324 95 0.052
Human Mouse
organelle assembly GO:0070925 214 0.051
muscle structure development GO:0061061 191 0.050
oogenesis GO:0048477 229 0.050
autophagy GO:0006914 29 0.049
regulation of meiotic cell cycle GO:0051445 136 0.049
regulation of locomotion GO:0040012 161 0.048
Worm
positive regulation of signaling GO:0023056 66 0.047
positive regulation of nucleic acid templated transcription GO:1903508 102 0.047
Mouse
multi multicellular organism process GO:0044706 390 0.047
gene silencing GO:0016458 143 0.046
lipid metabolic process GO:0006629 77 0.046
regulation of cell cycle GO:0051726 194 0.045
localization of cell GO:0051674 313 0.045
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.045
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.045
programmed cell death GO:0012501 500 0.045
carbohydrate derivative metabolic process GO:1901135 141 0.045
regulation of response to stimulus GO:0048583 243 0.044
Mouse
chromosome organization GO:0051276 104 0.043
Mouse
regulation of meiosis GO:0040020 94 0.042
protein catabolic process GO:0030163 162 0.042
Human Worm
phosphate containing compound metabolic process GO:0006796 232 0.042
negative regulation of nucleic acid templated transcription GO:1903507 53 0.042
Human Mouse
negative regulation of biosynthetic process GO:0009890 65 0.041
Human Mouse
nucleobase containing compound catabolic process GO:0034655 114 0.041
posttranscriptional gene silencing GO:0016441 143 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.041
Mouse
single organism behavior GO:0044708 83 0.041
Mouse
ribonucleotide metabolic process GO:0009259 99 0.041
establishment of localization in cell GO:0051649 318 0.041
cellular macromolecular complex assembly GO:0034622 184 0.038
cellular component movement GO:0006928 388 0.038
Worm
cell type specific apoptotic process GO:0097285 4 0.038
meiotic chromosome segregation GO:0045132 139 0.037
response to external stimulus GO:0009605 289 0.037
Mouse
regulation of cell fate specification GO:0042659 22 0.037
enzyme linked receptor protein signaling pathway GO:0007167 50 0.036
ribonucleoside catabolic process GO:0042454 77 0.036
negative regulation of cellular biosynthetic process GO:0031327 65 0.035
Human Mouse
cell growth GO:0016049 44 0.034
nucleotide metabolic process GO:0009117 108 0.034
regulation of cell migration GO:0030334 55 0.033
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.033
Human Mouse
nucleoside catabolic process GO:0009164 78 0.033
cell adhesion GO:0007155 21 0.033
Worm
microtubule based process GO:0007017 182 0.033
gene silencing by rna GO:0031047 143 0.032
adult behavior GO:0030534 3 0.032
cuticle development GO:0042335 100 0.032
regionalization GO:0003002 31 0.032
protein localization GO:0008104 205 0.032
cell motility GO:0048870 313 0.032
Worm
apoptotic process GO:0006915 478 0.031
cellular protein localization GO:0034613 75 0.031
fertilization GO:0009566 63 0.031
regulation of cell fate commitment GO:0010453 22 0.031
regulation of translation GO:0006417 19 0.031
mesoderm development GO:0007498 27 0.031
Worm
purine nucleoside catabolic process GO:0006152 75 0.031
single fertilization GO:0007338 61 0.030
gastrulation GO:0007369 58 0.030
locomotory behavior GO:0007626 40 0.030
Mouse
posttranscriptional gene silencing by rna GO:0035194 143 0.030
cellular protein complex assembly GO:0043623 178 0.030
covalent chromatin modification GO:0016569 30 0.030
Mouse
phosphorus metabolic process GO:0006793 232 0.029
nematode male tail tip morphogenesis GO:0045138 77 0.029
Worm
actin filament based process GO:0030029 191 0.029
death GO:0016265 547 0.029
regulation of organelle organization GO:0033043 164 0.028
protein complex biogenesis GO:0070271 186 0.028
nucleoside phosphate metabolic process GO:0006753 108 0.028
regulation of cell differentiation GO:0045595 81 0.028
rna interference GO:0016246 137 0.028
signal release GO:0023061 28 0.027
striated muscle cell differentiation GO:0051146 158 0.027
generation of neurons GO:0048699 235 0.027
skeletal muscle organ development GO:0060538 3 0.027
chromatin organization GO:0006325 32 0.026
Mouse
nucleoside triphosphate metabolic process GO:0009141 87 0.026
protein metabolic process GO:0019538 422 0.026
Human Mouse Worm
positive regulation of cell migration GO:0030335 3 0.026
regulation of anatomical structure size GO:0090066 46 0.026
aromatic compound catabolic process GO:0019439 116 0.026
cell recognition GO:0008037 85 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.026
adult locomotory behavior GO:0008344 1 0.026
positive regulation of neurogenesis GO:0050769 4 0.025
ribonucleoprotein complex assembly GO:0022618 4 0.025
organic substance catabolic process GO:1901575 294 0.025
Human Worm
spindle localization GO:0051653 51 0.025
homeostatic process GO:0042592 51 0.025
intracellular receptor signaling pathway GO:0030522 2 0.024
cell proliferation GO:0008283 116 0.024
glycosyl compound catabolic process GO:1901658 79 0.024
regulation of neuron differentiation GO:0045664 40 0.024
developmental cell growth GO:0048588 39 0.024
purine nucleoside metabolic process GO:0042278 92 0.023
striated muscle cell development GO:0055002 157 0.023
regulation of lipid metabolic process GO:0019216 4 0.023
nucleoside triphosphate catabolic process GO:0009143 72 0.023
regulation of cell morphogenesis GO:0022604 40 0.023
organophosphate metabolic process GO:0019637 125 0.023
oocyte differentiation GO:0009994 45 0.023
ras protein signal transduction GO:0007265 31 0.023
collagen and cuticulin based cuticle development GO:0040002 99 0.023
glycosyl compound metabolic process GO:1901657 100 0.022
cell cell signaling GO:0007267 118 0.022
protein modification process GO:0036211 207 0.022
Human Mouse
purine nucleoside triphosphate metabolic process GO:0009144 87 0.022
small gtpase mediated signal transduction GO:0007264 32 0.022
asymmetric cell division GO:0008356 36 0.022
Worm
axonal fasciculation GO:0007413 79 0.022
actin cytoskeleton organization GO:0030036 184 0.022
oxoacid metabolic process GO:0043436 47 0.022
regulation of localization GO:0032879 194 0.022
Worm
macromolecule modification GO:0043412 218 0.022
Human Mouse
nucleobase containing small molecule metabolic process GO:0055086 115 0.022
purine nucleoside triphosphate catabolic process GO:0009146 72 0.021
phagocytosis GO:0006909 115 0.021
organophosphate catabolic process GO:0046434 81 0.021
nucleoside phosphate catabolic process GO:1901292 77 0.021
negative regulation of rna biosynthetic process GO:1902679 53 0.021
Human Mouse
cellular response to chemical stimulus GO:0070887 129 0.021
regulation of anatomical structure morphogenesis GO:0022603 51 0.021
axis specification GO:0009798 23 0.021
cell surface receptor signaling pathway GO:0007166 149 0.021
Worm
inductive cell migration GO:0040039 145 0.021
neuromuscular junction development GO:0007528 2 0.021
response to unfolded protein GO:0006986 71 0.021
small molecule metabolic process GO:0044281 186 0.021
chromatin modification GO:0016568 32 0.020
Mouse
epithelial tube morphogenesis GO:0060562 1 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
positive regulation of rna metabolic process GO:0051254 103 0.020
Mouse
epidermis development GO:0008544 24 0.020
Worm
system process GO:0003008 136 0.020
g protein coupled receptor signaling pathway GO:0007186 46 0.020
dendrite development GO:0016358 42 0.020
positive regulation of cellular metabolic process GO:0031325 178 0.020
Human Mouse
ribonucleoside metabolic process GO:0009119 98 0.020
regulation of cell proliferation GO:0042127 105 0.020
regulation of macromolecule biosynthetic process GO:0010556 189 0.019
Human Mouse
organic cyclic compound catabolic process GO:1901361 119 0.019
gtp metabolic process GO:0046039 46 0.019
positive regulation of catabolic process GO:0009896 38 0.019
cellular nitrogen compound catabolic process GO:0044270 119 0.019
heterocycle catabolic process GO:0046700 119 0.019
regulation of cell cycle process GO:0010564 145 0.019
regulation of signal transduction GO:0009966 135 0.019
tissue development GO:0009888 112 0.019
Zebrafish Worm
regulation of cell division GO:0051302 142 0.019
Worm
secretion GO:0046903 147 0.019
cellular response to dna damage stimulus GO:0006974 41 0.019
Human Mouse
spermatogenesis GO:0007283 41 0.019
regulation of synapse assembly GO:0051963 2 0.019
dauer larval development GO:0040024 92 0.019
neuron recognition GO:0008038 83 0.019
engulfment of apoptotic cell GO:0043652 94 0.019
cellular ketone metabolic process GO:0042180 14 0.018
positive regulation of response to stimulus GO:0048584 55 0.018
positive regulation of locomotion GO:0040017 42 0.018
response to organic substance GO:0010033 131 0.018
Mouse
regulation of apoptotic signaling pathway GO:2001233 1 0.018
neuron projection extension GO:1990138 37 0.018
organic substance transport GO:0071702 113 0.018
carboxylic acid metabolic process GO:0019752 34 0.017
negative regulation of neurogenesis GO:0050768 4 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.017
stress activated protein kinase signaling cascade GO:0031098 10 0.017
chromosome segregation GO:0007059 180 0.017
chromatin remodeling GO:0006338 2 0.017
notch signaling pathway GO:0007219 22 0.017
secretion by cell GO:0032940 138 0.017
wnt signaling pathway GO:0016055 27 0.017
Worm
macromolecule catabolic process GO:0009057 202 0.017
Human Worm
membrane invagination GO:0010324 98 0.017
actomyosin structure organization GO:0031032 154 0.017
establishment of spindle localization GO:0051293 51 0.017
ribose phosphate metabolic process GO:0019693 99 0.017
embryonic digestive tract development GO:0048566 13 0.017
response to external biotic stimulus GO:0043207 101 0.016
Mouse
detection of external stimulus GO:0009581 4 0.016
positive regulation of neuron differentiation GO:0045666 4 0.016
regulation of cellular component movement GO:0051270 62 0.016
Worm
cellular macromolecule localization GO:0070727 75 0.016
cellular response to unfolded protein GO:0034620 71 0.016
cellular amino acid metabolic process GO:0006520 15 0.016
organic acid metabolic process GO:0006082 47 0.016
cellular response to organic substance GO:0071310 119 0.016
purine ribonucleotide catabolic process GO:0009154 75 0.016
peptidyl tyrosine phosphorylation GO:0018108 2 0.016
organonitrogen compound metabolic process GO:1901564 151 0.016
purine nucleotide metabolic process GO:0006163 95 0.016
purine nucleotide catabolic process GO:0006195 75 0.016
ribonucleoside triphosphate catabolic process GO:0009203 72 0.016
ribosome biogenesis GO:0042254 4 0.016
regulation of cell projection assembly GO:0060491 3 0.016
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
nucleoside metabolic process GO:0009116 99 0.015
regulation of mitotic cell cycle GO:0007346 76 0.015
spindle organization GO:0007051 92 0.015
establishment of mitotic spindle localization GO:0040001 41 0.015
rho protein signal transduction GO:0007266 2 0.015
hormone transport GO:0009914 2 0.015
phagocytosis engulfment GO:0006911 98 0.015
regulation of nuclear division GO:0051783 115 0.015
defense response GO:0006952 296 0.015
Mouse
organonitrogen compound catabolic process GO:1901565 90 0.015
carbohydrate derivative catabolic process GO:1901136 82 0.015
cellular protein modification process GO:0006464 207 0.015
Human Mouse
regulation of cellular component size GO:0032535 40 0.015
chromatin assembly or disassembly GO:0006333 1 0.014
positive regulation of nucleoside metabolic process GO:0045979 28 0.014
stress activated mapk cascade GO:0051403 10 0.014
mitotic g2 m transition checkpoint GO:0044818 1 0.014
regulation of gtp catabolic process GO:0033124 32 0.014
apoptotic cell clearance GO:0043277 111 0.014
amine metabolic process GO:0009308 15 0.014
translation GO:0006412 37 0.014
intracellular signal transduction GO:0035556 96 0.014
purine containing compound catabolic process GO:0072523 75 0.014
muscle tissue development GO:0060537 1 0.014
establishment or maintenance of cell polarity GO:0007163 63 0.014
Worm
response to abiotic stimulus GO:0009628 152 0.014
Human Mouse
pharynx development GO:0060465 51 0.014
regulation of cytoskeleton organization GO:0051493 41 0.014
regulation of filopodium assembly GO:0051489 2 0.014
gtp catabolic process GO:0006184 46 0.014
oocyte axis specification GO:0007309 2 0.014
regulation of catabolic process GO:0009894 57 0.014
rna localization GO:0006403 3 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.014
positive regulation of gtp catabolic process GO:0033126 28 0.013
regulation of rna splicing GO:0043484 7 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
negative regulation of rna metabolic process GO:0051253 53 0.013
Human Mouse
negative regulation of gene expression epigenetic GO:0045814 2 0.013
innate immune response GO:0045087 190 0.013
male gamete generation GO:0048232 41 0.013
cell substrate adhesion GO:0031589 1 0.013
biological adhesion GO:0022610 21 0.013
Worm
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.013
oocyte development GO:0048599 44 0.013
regulation of organ morphogenesis GO:2000027 4 0.013
regulation of jun kinase activity GO:0043506 3 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
embryonic organ development GO:0048568 17 0.013
Zebrafish
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
cellular component assembly involved in morphogenesis GO:0010927 183 0.013
positive regulation of biosynthetic process GO:0009891 109 0.013
Mouse
regulation of cell motility GO:2000145 57 0.013
Worm
positive regulation of cellular catabolic process GO:0031331 35 0.013
negative regulation of signal transduction GO:0009968 60 0.013
tissue morphogenesis GO:0048729 65 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
male anatomical structure morphogenesis GO:0090598 78 0.012
Worm
guanosine containing compound catabolic process GO:1901069 48 0.012
lateral inhibition GO:0046331 3 0.012
negative regulation of mitotic cell cycle GO:0045930 42 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.012
protein phosphorylation GO:0006468 85 0.012
purine ribonucleoside metabolic process GO:0046128 92 0.012
ubiquitin dependent protein catabolic process GO:0006511 32 0.012
Human
negative regulation of cellular component organization GO:0051129 33 0.012
axon extension GO:0048675 37 0.012
regulation of cellular component biogenesis GO:0044087 26 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
negative regulation of cell communication GO:0010648 61 0.011
nucleotide catabolic process GO:0009166 77 0.011
phosphorylation GO:0016310 116 0.011
establishment of protein localization to membrane GO:0090150 3 0.011
negative regulation of cellular protein metabolic process GO:0032269 27 0.011
response to topologically incorrect protein GO:0035966 82 0.011
regulation of lamellipodium assembly GO:0010591 1 0.011
actin filament bundle assembly GO:0051017 3 0.011
endosomal transport GO:0016197 26 0.011
internal peptidyl lysine acetylation GO:0018393 3 0.011
nitrogen compound transport GO:0071705 49 0.011
intracellular transport GO:0046907 77 0.011
protein polymerization GO:0051258 26 0.011
regulation of phosphorus metabolic process GO:0051174 81 0.011
myosin filament organization GO:0031033 138 0.011
pigmentation GO:0043473 2 0.011
nucleus localization GO:0051647 55 0.011
single organism cellular localization GO:1902580 72 0.011
muscle cell development GO:0055001 158 0.011
nuclear migration GO:0007097 54 0.011
establishment of cell polarity GO:0030010 46 0.011
regulation of hormone secretion GO:0046883 2 0.011
dorsal ventral axon guidance GO:0033563 19 0.011
response to endoplasmic reticulum stress GO:0034976 71 0.011
regulation of cell projection organization GO:0031344 38 0.011

lin-40 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.017
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.011