Caenorhabditis elegans

19 known processes

his-12 (CELE_ZK131.6)

Protein HIS-12

his-12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.203
embryo development ending in birth or egg hatching GO:0009792 2992 0.191
locomotion GO:0040011 1634 0.184
post embryonic development GO:0009791 2152 0.172
Worm
organ development GO:0048513 1102 0.127
Worm
reproductive system development GO:0061458 850 0.123
Worm
organelle organization GO:0006996 783 0.113
Worm
hermaphrodite genitalia development GO:0040035 734 0.111
Worm
developmental process involved in reproduction GO:0003006 1165 0.107
Worm
reproductive structure development GO:0048608 850 0.106
Worm
single organism reproductive process GO:0044702 1196 0.106
Worm
transport GO:0006810 1093 0.102
development of primary sexual characteristics GO:0045137 840 0.102
Worm
gonad development GO:0008406 840 0.099
Worm
sex differentiation GO:0007548 909 0.096
Worm
establishment of localization GO:0051234 1171 0.095
multi organism reproductive process GO:0044703 867 0.091
Worm
genitalia development GO:0048806 741 0.091
Worm
determination of adult lifespan GO:0008340 812 0.091
multicellular organismal aging GO:0010259 812 0.090
vesicle mediated transport GO:0016192 852 0.089
endocytosis GO:0006897 819 0.084
macromolecule localization GO:0033036 771 0.084
aging GO:0007568 812 0.081
multicellular organism reproduction GO:0032504 819 0.080
Worm
multicellular organismal reproductive process GO:0048609 815 0.078
Worm
cell death GO:0008219 547 0.078
Worm
regulation of biological quality GO:0065008 741 0.076
body morphogenesis GO:0010171 620 0.073
behavior GO:0007610 527 0.073
Worm
receptor mediated endocytosis GO:0006898 715 0.072
death GO:0016265 547 0.068
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.067
Worm
maintenance of location GO:0051235 580 0.067
lipid localization GO:0010876 573 0.067
programmed cell death GO:0012501 500 0.066
Worm
lipid storage GO:0019915 565 0.063
cell cycle GO:0007049 526 0.062
regulation of multicellular organismal process GO:0051239 726 0.061
multi organism reproductive behavior GO:0044705 387 0.059
Worm
cell development GO:0048468 696 0.057
defense response GO:0006952 296 0.055
growth GO:0040007 562 0.050
regulation of macromolecule metabolic process GO:0060255 421 0.050
Yeast
multi organism behavior GO:0051705 389 0.050
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.049
regulation of developmental process GO:0050793 684 0.049
reproductive behavior GO:0019098 387 0.048
Worm
oviposition GO:0018991 364 0.048
Worm
developmental growth GO:0048589 412 0.047
single organism transport GO:0044765 447 0.047
apoptotic process GO:0006915 478 0.047
Worm
positive regulation of developmental process GO:0051094 408 0.046
cell cycle process GO:0022402 482 0.046
regulation of developmental growth GO:0048638 389 0.045
positive regulation of multicellular organism growth GO:0040018 352 0.045
macromolecular complex subunit organization GO:0043933 320 0.045
positive regulation of developmental growth GO:0048639 354 0.044
regulation of growth GO:0040008 409 0.044
positive regulation of growth GO:0045927 369 0.044
sexual reproduction GO:0019953 546 0.043
multi multicellular organism process GO:0044706 390 0.043
Worm
negative regulation of biological process GO:0048519 567 0.043
Yeast
single organism organelle organization GO:1902589 501 0.042
molting cycle GO:0042303 281 0.042
regulation of multicellular organism growth GO:0040014 373 0.041
multicellular organism growth GO:0035264 385 0.040
organelle fission GO:0048285 363 0.040
single organism localization GO:1902578 518 0.040
regulation of metabolic process GO:0019222 478 0.039
Yeast
cytoskeleton organization GO:0007010 339 0.037
cellular component movement GO:0006928 388 0.037
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.037
biosynthetic process GO:0009058 323 0.037
Yeast
nucleobase containing compound metabolic process GO:0006139 406 0.037
Yeast
digestive system development GO:0055123 122 0.036
cellular biosynthetic process GO:0044249 315 0.036
Yeast
digestive tract development GO:0048565 122 0.035
gene expression GO:0010467 412 0.035
Yeast
meiotic cell cycle GO:0051321 335 0.035
organic substance biosynthetic process GO:1901576 323 0.034
Yeast
negative regulation of macromolecule metabolic process GO:0010605 229 0.034
Yeast
regulation of gene expression GO:0010468 366 0.034
Yeast
cellular macromolecule biosynthetic process GO:0034645 247 0.034
Yeast
cellular component morphogenesis GO:0032989 318 0.032
organelle assembly GO:0070925 214 0.032
transcription dna templated GO:0006351 168 0.031
Yeast
establishment of localization in cell GO:0051649 318 0.031
cellular nitrogen compound biosynthetic process GO:0044271 192 0.031
Yeast
cell division GO:0051301 262 0.031
gamete generation GO:0007276 461 0.030
tube development GO:0035295 126 0.030
cell migration GO:0016477 306 0.029
protein metabolic process GO:0019538 422 0.029
protein complex subunit organization GO:0071822 280 0.029
cellular component biogenesis GO:0044085 297 0.029
meiotic nuclear division GO:0007126 300 0.029
macromolecule biosynthetic process GO:0009059 250 0.029
Yeast
aromatic compound biosynthetic process GO:0019438 192 0.028
Yeast
cellular component assembly GO:0022607 293 0.028
regulation of gene expression epigenetic GO:0040029 163 0.028
Yeast
vulval development GO:0040025 333 0.028
localization of cell GO:0051674 313 0.028
rna metabolic process GO:0016070 228 0.028
Yeast
organic cyclic compound biosynthetic process GO:1901362 195 0.027
Yeast
cell motility GO:0048870 313 0.027
nucleic acid metabolic process GO:0090304 299 0.026
Yeast
regulation of primary metabolic process GO:0080090 292 0.026
Yeast
gene silencing GO:0016458 143 0.026
Yeast
immune response GO:0006955 192 0.026
cellular macromolecular complex assembly GO:0034622 184 0.026
actin cytoskeleton organization GO:0030036 184 0.025
actomyosin structure organization GO:0031032 154 0.025
regulation of multicellular organismal development GO:2000026 317 0.025
cellular protein complex assembly GO:0043623 178 0.025
response to wounding GO:0009611 4 0.025
germ cell development GO:0007281 351 0.025
meiotic cell cycle process GO:1903046 170 0.025
anatomical structure formation involved in morphogenesis GO:0048646 250 0.025
negative regulation of metabolic process GO:0009892 240 0.025
Yeast
cellular component assembly involved in morphogenesis GO:0010927 183 0.025
single organism signaling GO:0044700 401 0.025
actin filament based process GO:0030029 191 0.024
regulation of organelle organization GO:0033043 164 0.024
regulation of transcription dna templated GO:0006355 164 0.024
Yeast
catabolic process GO:0009056 318 0.024
protein complex biogenesis GO:0070271 186 0.024
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.024
myofibril assembly GO:0030239 154 0.024
protein complex assembly GO:0006461 186 0.024
regulation of cellular component organization GO:0051128 248 0.024
regulation of cellular metabolic process GO:0031323 305 0.024
Yeast
cellular localization GO:0051641 360 0.024
post embryonic organ development GO:0048569 336 0.023
pharynx development GO:0060465 51 0.023
negative regulation of gene expression GO:0010629 217 0.023
Yeast
heterocycle biosynthetic process GO:0018130 187 0.023
Yeast
innate immune response GO:0045087 190 0.023
rna biosynthetic process GO:0032774 169 0.023
Yeast
organic substance catabolic process GO:1901575 294 0.022
macromolecule catabolic process GO:0009057 202 0.022
negative regulation of gene expression epigenetic GO:0045814 2 0.022
Yeast
head development GO:0060322 1 0.022
transcription from rna polymerase ii promoter GO:0006366 149 0.022
Yeast
striated muscle myosin thick filament assembly GO:0071688 138 0.022
response to chemical GO:0042221 356 0.022
muscle cell differentiation GO:0042692 171 0.022
macromolecular complex assembly GO:0065003 193 0.021
regulation of rna biosynthetic process GO:2001141 165 0.021
Yeast
cell projection organization GO:0030030 231 0.021
regulation of biosynthetic process GO:0009889 189 0.021
Yeast
negative regulation of cellular process GO:0048523 239 0.021
Yeast
response to external stimulus GO:0009605 289 0.021
striated muscle cell development GO:0055002 157 0.021
muscle cell development GO:0055001 158 0.021
positive regulation of cellular process GO:0048522 332 0.021
sensory organ morphogenesis GO:0090596 2 0.021
regulation of vulval development GO:0040028 248 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.020
Yeast
nucleobase containing compound biosynthetic process GO:0034654 184 0.020
Yeast
small molecule metabolic process GO:0044281 186 0.020
signaling GO:0023052 401 0.020
negative regulation of developmental process GO:0051093 227 0.020
regulation of post embryonic development GO:0048580 260 0.020
myosin filament assembly GO:0031034 138 0.020
regulation of nitrogen compound metabolic process GO:0051171 222 0.020
Yeast
axon development GO:0061564 163 0.020
regulation of macromolecule biosynthetic process GO:0010556 189 0.020
Yeast
macromolecule modification GO:0043412 218 0.019
cellular protein metabolic process GO:0044267 279 0.019
striated muscle cell differentiation GO:0051146 158 0.019
myosin filament organization GO:0031033 138 0.019
regulation of nematode larval development GO:0061062 260 0.019
cellular protein modification process GO:0006464 207 0.019
regulation of cytoplasmic transport GO:1903649 3 0.019
nucleic acid templated transcription GO:0097659 169 0.019
Yeast
chromatin assembly or disassembly GO:0006333 1 0.019
muscle structure development GO:0061061 191 0.019
negative regulation of multicellular organismal process GO:0051241 236 0.019
neurogenesis GO:0022008 236 0.019
regulation of cell division GO:0051302 142 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.019
Yeast
negative regulation of post embryonic development GO:0048581 208 0.018
inductive cell migration GO:0040039 145 0.018
regulation of nuclear division GO:0051783 115 0.018
nervous system development GO:0007399 253 0.018
posttranscriptional gene silencing GO:0016441 143 0.018
regulation of cell cycle GO:0051726 194 0.018
regulation of nucleic acid templated transcription GO:1903506 165 0.018
Yeast
dna metabolic process GO:0006259 74 0.018
Yeast
protein modification process GO:0036211 207 0.018
gene silencing by rna GO:0031047 143 0.018
regulation of localization GO:0032879 194 0.017
organonitrogen compound metabolic process GO:1901564 151 0.017
protein localization GO:0008104 205 0.017
posttranscriptional gene silencing by rna GO:0035194 143 0.017
regulation of response to stimulus GO:0048583 243 0.017
chromosome segregation GO:0007059 180 0.017
female gamete generation GO:0007292 254 0.017
oogenesis GO:0048477 229 0.016
generation of neurons GO:0048699 235 0.016
negative regulation of vulval development GO:0040027 206 0.016
negative regulation of nematode larval development GO:0061064 208 0.016
signal transduction GO:0007165 317 0.016
secretion by cell GO:0032940 138 0.016
cellular catabolic process GO:0044248 199 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
regulation of rna metabolic process GO:0051252 173 0.016
Yeast
mitotic cell cycle process GO:1903047 194 0.016
posttranscriptional regulation of gene expression GO:0010608 166 0.016
rna interference GO:0016246 137 0.016
regulation of cellular biosynthetic process GO:0031326 189 0.016
Yeast
regulation of meiotic cell cycle GO:0051445 136 0.016
chromosome organization GO:0051276 104 0.016
cellular response to stress GO:0033554 162 0.016
Yeast
secretion GO:0046903 147 0.016
neuron projection development GO:0031175 187 0.016
regulation of nucleocytoplasmic transport GO:0046822 3 0.015
microtubule based process GO:0007017 182 0.015
phosphorus metabolic process GO:0006793 232 0.015
protein catabolic process GO:0030163 162 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.015
Yeast
regulation of cellular amine metabolic process GO:0033238 0 0.015
regulation of cell communication GO:0010646 176 0.015
membrane organization GO:0061024 135 0.015
neuromuscular junction development GO:0007528 2 0.015
phosphate containing compound metabolic process GO:0006796 232 0.015
oxoacid metabolic process GO:0043436 47 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.014
chemotaxis GO:0006935 120 0.014
positive regulation of neurogenesis GO:0050769 4 0.014
cell part morphogenesis GO:0032990 152 0.014
neuron development GO:0048666 199 0.014
phagocytosis GO:0006909 115 0.014
cell type specific apoptotic process GO:0097285 4 0.014
regeneration GO:0031099 4 0.014
ribosome biogenesis GO:0042254 4 0.014
neuron differentiation GO:0030182 217 0.014
apoptotic cell clearance GO:0043277 111 0.013
meiotic chromosome segregation GO:0045132 139 0.013
adult behavior GO:0030534 3 0.013
regulation of meiosis GO:0040020 94 0.013
cell projection morphogenesis GO:0048858 148 0.013
taxis GO:0042330 128 0.013
positive regulation of metabolic process GO:0009893 187 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
cellular ketone metabolic process GO:0042180 14 0.013
regulation of cell cycle process GO:0010564 145 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
amine metabolic process GO:0009308 15 0.013
collagen and cuticulin based cuticle development GO:0040002 99 0.013
cuticle development GO:0042335 100 0.013
negative regulation of neurogenesis GO:0050768 4 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.012
engulfment of apoptotic cell GO:0043652 94 0.012
phagocytosis engulfment GO:0006911 98 0.012
regulation of signaling GO:0023051 172 0.012
embryonic morphogenesis GO:0048598 152 0.012
cell morphogenesis GO:0000902 163 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
Yeast
regulation of cell proliferation GO:0042127 105 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.012
Yeast
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
neuron projection morphogenesis GO:0048812 114 0.012
protein oligomerization GO:0051259 4 0.012
lipid metabolic process GO:0006629 77 0.012
organic acid metabolic process GO:0006082 47 0.011
axon guidance GO:0007411 82 0.011
cell proliferation GO:0008283 116 0.011
response to abiotic stimulus GO:0009628 152 0.011
membrane invagination GO:0010324 98 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
canonical wnt signaling pathway GO:0060070 3 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
regulation of protein targeting GO:1903533 3 0.011
establishment of organelle localization GO:0051656 123 0.011
regulation of lipid metabolic process GO:0019216 4 0.011
ion transport GO:0006811 113 0.011
cellular amine metabolic process GO:0044106 15 0.011
organic substance transport GO:0071702 113 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
Yeast
peptidyl tyrosine phosphorylation GO:0018108 2 0.010
regulation of signal transduction GO:0009966 135 0.010
positive regulation of cellular metabolic process GO:0031325 178 0.010
rna localization GO:0006403 3 0.010
feeding behavior GO:0007631 70 0.010
cell substrate adhesion GO:0031589 1 0.010
regulation of response to wounding GO:1903034 1 0.010
mitotic nuclear division GO:0007067 89 0.010
cellular nitrogen compound catabolic process GO:0044270 119 0.010
cytokinesis GO:0000910 80 0.010
response to organic substance GO:0010033 131 0.010
skeletal muscle organ development GO:0060538 3 0.010
system process GO:0003008 136 0.010

his-12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.012