Caenorhabditis elegans

22 known processes

his-14 (CELE_ZK131.8)

Protein HIS-14

his-14 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.719
hermaphrodite genitalia development GO:0040035 734 0.648
Worm
embryo development GO:0009790 3052 0.647
single organism reproductive process GO:0044702 1196 0.626
Yeast Worm
developmental process involved in reproduction GO:0003006 1165 0.564
Yeast Worm
post embryonic development GO:0009791 2152 0.552
Worm
genitalia development GO:0048806 741 0.537
Worm
digestive tract development GO:0048565 122 0.488
reproductive system development GO:0061458 850 0.481
Worm
meiotic cell cycle process GO:1903046 170 0.458
Yeast
locomotion GO:0040011 1634 0.435
digestive system development GO:0055123 122 0.417
development of primary sexual characteristics GO:0045137 840 0.409
Worm
organ development GO:0048513 1102 0.407
Worm
tube development GO:0035295 126 0.400
gonad development GO:0008406 840 0.394
Worm
reproductive structure development GO:0048608 850 0.385
Worm
multicellular organism reproduction GO:0032504 819 0.385
sex differentiation GO:0007548 909 0.358
Worm
meiotic cell cycle GO:0051321 335 0.332
Yeast
defense response GO:0006952 296 0.327
pharynx development GO:0060465 51 0.318
negative regulation of gene expression epigenetic GO:0045814 2 0.318
Yeast
multicellular organismal reproductive process GO:0048609 815 0.296
organic substance biosynthetic process GO:1901576 323 0.283
Yeast Worm
nucleobase containing compound metabolic process GO:0006139 406 0.263
Yeast Worm
aromatic compound biosynthetic process GO:0019438 192 0.263
Yeast Worm
multi organism reproductive process GO:0044703 867 0.259
Yeast
multicellular organismal reproductive behavior GO:0033057 384 0.248
sexual reproduction GO:0019953 546 0.229
Yeast
heterocycle biosynthetic process GO:0018130 187 0.229
Yeast Worm
regulation of macromolecule metabolic process GO:0060255 421 0.226
Yeast Worm
cellular nitrogen compound biosynthetic process GO:0044271 192 0.223
Yeast Worm
nucleic acid metabolic process GO:0090304 299 0.213
Yeast Worm
macromolecular complex subunit organization GO:0043933 320 0.213
Yeast
oviposition GO:0018991 364 0.205
regulation of cellular metabolic process GO:0031323 305 0.203
Yeast Worm
negative regulation of cellular process GO:0048523 239 0.190
Yeast
organelle organization GO:0006996 783 0.185
Yeast
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.175
Yeast Worm
gene expression GO:0010467 412 0.173
Yeast Worm
rna biosynthetic process GO:0032774 169 0.173
Yeast Worm
regulation of primary metabolic process GO:0080090 292 0.170
Yeast Worm
regulation of rna biosynthetic process GO:2001141 165 0.169
Yeast Worm
macromolecule biosynthetic process GO:0009059 250 0.165
Yeast Worm
regulation of rna metabolic process GO:0051252 173 0.157
Yeast Worm
negative regulation of biological process GO:0048519 567 0.155
Yeast
organic cyclic compound biosynthetic process GO:1901362 195 0.155
Yeast Worm
transcription dna templated GO:0006351 168 0.154
Yeast Worm
cellular biosynthetic process GO:0044249 315 0.154
Yeast Worm
biosynthetic process GO:0009058 323 0.153
Yeast Worm
negative regulation of gene expression GO:0010629 217 0.150
Yeast
negative regulation of metabolic process GO:0009892 240 0.147
Yeast
regulation of nitrogen compound metabolic process GO:0051171 222 0.146
Yeast Worm
negative regulation of transcription dna templated GO:0045892 53 0.145
Yeast
regulation of metabolic process GO:0019222 478 0.137
Yeast Worm
protein complex subunit organization GO:0071822 280 0.133
regulation of biosynthetic process GO:0009889 189 0.132
Yeast Worm
innate immune response GO:0045087 190 0.130
single organism organelle organization GO:1902589 501 0.127
Yeast
cell development GO:0048468 696 0.125
positive regulation of transcription dna templated GO:0045893 102 0.124
Worm
single organism transport GO:0044765 447 0.123
cellular component morphogenesis GO:0032989 318 0.122
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.121
Yeast Worm
regulation of cellular biosynthetic process GO:0031326 189 0.120
Yeast Worm
cell cycle GO:0007049 526 0.119
Yeast
regulation of nucleic acid templated transcription GO:1903506 165 0.113
Yeast Worm
chromatin assembly or disassembly GO:0006333 1 0.113
receptor mediated endocytosis GO:0006898 715 0.112
negative regulation of macromolecule metabolic process GO:0010605 229 0.112
Yeast
vesicle mediated transport GO:0016192 852 0.111
endocytosis GO:0006897 819 0.110
establishment of localization GO:0051234 1171 0.107
gamete generation GO:0007276 461 0.106
multi multicellular organism process GO:0044706 390 0.106
nucleic acid templated transcription GO:0097659 169 0.105
Yeast Worm
single organism localization GO:1902578 518 0.102
dna metabolic process GO:0006259 74 0.100
positive regulation of macromolecule metabolic process GO:0010604 149 0.099
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.099
Yeast Worm
regulation of gene expression epigenetic GO:0040029 163 0.098
Yeast
body morphogenesis GO:0010171 620 0.096
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.095
Yeast
rna metabolic process GO:0016070 228 0.094
Yeast Worm
transport GO:0006810 1093 0.093
negative regulation of biosynthetic process GO:0009890 65 0.092
Yeast
cellular macromolecule biosynthetic process GO:0034645 247 0.090
Yeast Worm
establishment of localization in cell GO:0051649 318 0.089
gene silencing GO:0016458 143 0.088
Yeast
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.087
Yeast
nucleobase containing compound biosynthetic process GO:0034654 184 0.085
Yeast Worm
macromolecule localization GO:0033036 771 0.084
regulation of biological quality GO:0065008 741 0.083
cellular component assembly involved in morphogenesis GO:0010927 183 0.083
regulation of macromolecule biosynthetic process GO:0010556 189 0.083
Yeast Worm
regulation of gene expression GO:0010468 366 0.083
Yeast Worm
regulation of transcription dna templated GO:0006355 164 0.080
Yeast Worm
cytoskeleton organization GO:0007010 339 0.080
cellular component biogenesis GO:0044085 297 0.079
lipid localization GO:0010876 573 0.074
cellular localization GO:0051641 360 0.073
negative regulation of cellular biosynthetic process GO:0031327 65 0.073
Yeast
reproductive behavior GO:0019098 387 0.071
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.071
maintenance of location GO:0051235 580 0.070
organelle assembly GO:0070925 214 0.069
cellular component assembly GO:0022607 293 0.069
lipid storage GO:0019915 565 0.068
multi organism behavior GO:0051705 389 0.067
cellular protein metabolic process GO:0044267 279 0.066
Yeast
germ cell development GO:0007281 351 0.065
immune response GO:0006955 192 0.065
negative regulation of rna biosynthetic process GO:1902679 53 0.064
Yeast
meiotic nuclear division GO:0007126 300 0.061
cell cycle process GO:0022402 482 0.060
Yeast
transcription from rna polymerase ii promoter GO:0006366 149 0.060
Yeast Worm
muscle cell development GO:0055001 158 0.059
multi organism reproductive behavior GO:0044705 387 0.058
negative regulation of nucleic acid templated transcription GO:1903507 53 0.057
Yeast
secretion GO:0046903 147 0.057
actin filament based process GO:0030029 191 0.056
secretion by cell GO:0032940 138 0.056
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.056
Yeast
positive regulation of rna metabolic process GO:0051254 103 0.056
Worm
positive regulation of biosynthetic process GO:0009891 109 0.056
Worm
actin cytoskeleton organization GO:0030036 184 0.056
cellular response to dna damage stimulus GO:0006974 41 0.056
death GO:0016265 547 0.054
cellular protein complex assembly GO:0043623 178 0.053
cellular response to stress GO:0033554 162 0.053
muscle structure development GO:0061061 191 0.053
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.053
Yeast
dna repair GO:0006281 23 0.052
behavior GO:0007610 527 0.052
negative regulation of cellular metabolic process GO:0031324 95 0.051
Yeast
actomyosin structure organization GO:0031032 154 0.050
myofibril assembly GO:0030239 154 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.049
Yeast
chromosome organization GO:0051276 104 0.049
Yeast
macromolecule modification GO:0043412 218 0.049
Yeast
muscle cell differentiation GO:0042692 171 0.048
protein complex assembly GO:0006461 186 0.048
macromolecular complex assembly GO:0065003 193 0.048
striated muscle cell development GO:0055002 157 0.047
protein modification process GO:0036211 207 0.047
Yeast
myosin filament assembly GO:0031034 138 0.046
negative regulation of rna metabolic process GO:0051253 53 0.045
Yeast
protein complex biogenesis GO:0070271 186 0.045
anatomical structure formation involved in morphogenesis GO:0048646 250 0.044
Yeast
programmed cell death GO:0012501 500 0.044
cell death GO:0008219 547 0.043
signal transduction GO:0007165 317 0.043
oogenesis GO:0048477 229 0.043
protein metabolic process GO:0019538 422 0.041
Yeast
vulval development GO:0040025 333 0.041
cellular macromolecular complex assembly GO:0034622 184 0.041
determination of adult lifespan GO:0008340 812 0.041
positive regulation of cellular metabolic process GO:0031325 178 0.041
Worm
striated muscle cell differentiation GO:0051146 158 0.040
cellular protein modification process GO:0006464 207 0.040
Yeast
apoptotic process GO:0006915 478 0.040
growth GO:0040007 562 0.039
regulation of multicellular organismal process GO:0051239 726 0.037
positive regulation of cellular process GO:0048522 332 0.037
Worm
meiotic chromosome segregation GO:0045132 139 0.037
striated muscle myosin thick filament assembly GO:0071688 138 0.037
organelle fission GO:0048285 363 0.037
female gamete generation GO:0007292 254 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.034
Worm
myosin filament organization GO:0031033 138 0.034
negative regulation of nematode larval development GO:0061064 208 0.034
regulation of developmental process GO:0050793 684 0.034
aging GO:0007568 812 0.033
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.033
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.033
Worm
positive regulation of cellular biosynthetic process GO:0031328 109 0.033
Worm
positive regulation of developmental growth GO:0048639 354 0.032
regulation of multicellular organism growth GO:0040014 373 0.032
regulation of developmental growth GO:0048638 389 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.031
Worm
positive regulation of gene expression GO:0010628 112 0.030
Worm
regulation of nematode larval development GO:0061062 260 0.030
regulation of vulval development GO:0040028 248 0.029
developmental growth GO:0048589 412 0.029
regulation of growth GO:0040008 409 0.029
positive regulation of growth GO:0045927 369 0.029
nucleus organization GO:0006997 38 0.028
negative regulation of vulval development GO:0040027 206 0.028
multicellular organismal aging GO:0010259 812 0.028
histone modification GO:0016570 30 0.027
Yeast
multicellular organism growth GO:0035264 385 0.027
regulation of cellular component organization GO:0051128 248 0.027
organic substance catabolic process GO:1901575 294 0.027
macromolecule catabolic process GO:0009057 202 0.026
positive regulation of metabolic process GO:0009893 187 0.026
Worm
post embryonic organ development GO:0048569 336 0.026
single organism signaling GO:0044700 401 0.025
negative regulation of post embryonic development GO:0048581 208 0.025
cellular component movement GO:0006928 388 0.024
positive regulation of multicellular organism growth GO:0040018 352 0.024
negative regulation of developmental process GO:0051093 227 0.023
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.023
cell division GO:0051301 262 0.023
regulation of cell cycle GO:0051726 194 0.022
fertilization GO:0009566 63 0.022
positive regulation of developmental process GO:0051094 408 0.022
mitotic cell cycle process GO:1903047 194 0.022
positive regulation of rna biosynthetic process GO:1902680 102 0.022
Worm
regulation of mitotic cell cycle GO:0007346 76 0.021
negative regulation of multicellular organismal process GO:0051241 236 0.021
intracellular transport GO:0046907 77 0.021
cell morphogenesis GO:0000902 163 0.021
response to external stimulus GO:0009605 289 0.021
protein catabolic process GO:0030163 162 0.021
small molecule metabolic process GO:0044281 186 0.020
signaling GO:0023052 401 0.020
pronuclear migration GO:0035046 51 0.019
er nucleus signaling pathway GO:0006984 66 0.019
cellular response to topologically incorrect protein GO:0035967 76 0.019
muscle tissue development GO:0060537 1 0.019
cellular response to unfolded protein GO:0034620 71 0.018
cell morphogenesis involved in differentiation GO:0000904 112 0.018
response to chemical GO:0042221 356 0.018
chromosome segregation GO:0007059 180 0.018
posttranscriptional gene silencing GO:0016441 143 0.018
nervous system development GO:0007399 253 0.018
sensory organ morphogenesis GO:0090596 2 0.017
response to wounding GO:0009611 4 0.017
regulation of post embryonic development GO:0048580 260 0.017
protein localization GO:0008104 205 0.017
neurogenesis GO:0022008 236 0.017
response to unfolded protein GO:0006986 71 0.017
neuron projection development GO:0031175 187 0.017
cell motility GO:0048870 313 0.017
response to topologically incorrect protein GO:0035966 82 0.017
positive regulation of multicellular organismal process GO:0051240 417 0.017
endoplasmic reticulum unfolded protein response GO:0030968 66 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
posttranscriptional regulation of gene expression GO:0010608 166 0.016
molting cycle GO:0042303 281 0.016
inductive cell migration GO:0040039 145 0.016
rna interference GO:0016246 137 0.016
rna localization GO:0006403 3 0.016
cellular catabolic process GO:0044248 199 0.016
cell type specific apoptotic process GO:0097285 4 0.015
localization of cell GO:0051674 313 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
microtubule based process GO:0007017 182 0.015
oocyte axis specification GO:0007309 2 0.015
regulation of cell cycle process GO:0010564 145 0.015
regulation of multicellular organismal development GO:2000026 317 0.015
regulation of cytoplasmic transport GO:1903649 3 0.015
catabolic process GO:0009056 318 0.015
neuromuscular junction development GO:0007528 2 0.015
response to organic substance GO:0010033 131 0.015
head development GO:0060322 1 0.014
generation of neurons GO:0048699 235 0.014
response to abiotic stimulus GO:0009628 152 0.014
gene silencing by rna GO:0031047 143 0.014
cellular protein localization GO:0034613 75 0.014
regulation of organelle organization GO:0033043 164 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
single organism catabolic process GO:0044712 129 0.014
covalent chromatin modification GO:0016569 30 0.014
Yeast
axonogenesis GO:0007409 102 0.014
single fertilization GO:0007338 61 0.014
organonitrogen compound metabolic process GO:1901564 151 0.013
neuron projection morphogenesis GO:0048812 114 0.013
membrane organization GO:0061024 135 0.013
response to endoplasmic reticulum stress GO:0034976 71 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
regulation of transport GO:0051049 91 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
system process GO:0003008 136 0.013
protein oligomerization GO:0051259 4 0.013
organic substance transport GO:0071702 113 0.013
neuron projection guidance GO:0097485 82 0.013
chromatin modification GO:0016568 32 0.013
Yeast
apoptotic cell clearance GO:0043277 111 0.013
phosphate containing compound metabolic process GO:0006796 232 0.012
regulation of behavior GO:0050795 97 0.012
regulation of epithelial cell proliferation GO:0050678 1 0.012
skeletal muscle organ development GO:0060538 3 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
proteolysis GO:0006508 61 0.012
cellular response to organic substance GO:0071310 119 0.012
cell migration GO:0016477 306 0.012
neuron development GO:0048666 199 0.012
establishment of organelle localization GO:0051656 123 0.012
neuron differentiation GO:0030182 217 0.012
modification dependent protein catabolic process GO:0019941 32 0.012
phosphorus metabolic process GO:0006793 232 0.012
regulation of localization GO:0032879 194 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
axon guidance GO:0007411 82 0.011
cellular response to abiotic stimulus GO:0071214 4 0.011
cell projection organization GO:0030030 231 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.011
axon development GO:0061564 163 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
defense response to other organism GO:0098542 100 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
regulation of protein targeting GO:1903533 3 0.011
oocyte construction GO:0007308 2 0.011
single organism intracellular transport GO:1902582 70 0.011
cell part morphogenesis GO:0032990 152 0.011
membrane invagination GO:0010324 98 0.011
regulation of cell communication GO:0010646 176 0.011
phagocytosis engulfment GO:0006911 98 0.011
amine metabolic process GO:0009308 15 0.011
organophosphate metabolic process GO:0019637 125 0.011
intracellular signal transduction GO:0035556 96 0.011
positive regulation of nucleic acid templated transcription GO:1903508 102 0.011
Worm
cellular macromolecule catabolic process GO:0044265 73 0.011
defense response to bacterium GO:0042742 86 0.010
regulation of protein import into nucleus GO:0042306 3 0.010
regulation of cell division GO:0051302 142 0.010

his-14 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.013