Caenorhabditis elegans

0 known processes

hum-4 (CELE_F46C3.3)

Protein HUM-4

hum-4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 852 0.436
development of primary sexual characteristics GO:0045137 840 0.387
single organism localization GO:1902578 518 0.352
locomotion GO:0040011 1634 0.323
hermaphrodite genitalia development GO:0040035 734 0.288
system process GO:0003008 136 0.271
embryo development GO:0009790 3052 0.270
single organism behavior GO:0044708 83 0.265
determination of adult lifespan GO:0008340 812 0.250
establishment of localization GO:0051234 1171 0.239
organ development GO:0048513 1102 0.237
reproductive structure development GO:0048608 850 0.228
multi organism reproductive process GO:0044703 867 0.227
transport GO:0006810 1093 0.216
genitalia development GO:0048806 741 0.211
post embryonic development GO:0009791 2152 0.209
endocytosis GO:0006897 819 0.181
single organism transport GO:0044765 447 0.176
cellular nitrogen compound biosynthetic process GO:0044271 192 0.174
single organism organelle organization GO:1902589 501 0.172
heterocycle biosynthetic process GO:0018130 187 0.171
signaling GO:0023052 401 0.162
developmental process involved in reproduction GO:0003006 1165 0.161
multi organism reproductive behavior GO:0044705 387 0.161
embryo development ending in birth or egg hatching GO:0009792 2992 0.159
gonad development GO:0008406 840 0.155
single organism signaling GO:0044700 401 0.154
cell development GO:0048468 696 0.147
cell cycle process GO:0022402 482 0.145
regulation of response to stimulus GO:0048583 243 0.144
aromatic compound biosynthetic process GO:0019438 192 0.133
oviposition GO:0018991 364 0.131
multi organism behavior GO:0051705 389 0.129
reproductive system development GO:0061458 850 0.121
regulation of macromolecule biosynthetic process GO:0010556 189 0.116
behavior GO:0007610 527 0.116
programmed cell death GO:0012501 500 0.113
cellular localization GO:0051641 360 0.113
multicellular organismal reproductive behavior GO:0033057 384 0.111
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.108
reproductive behavior GO:0019098 387 0.102
receptor mediated endocytosis GO:0006898 715 0.102
gene expression GO:0010467 412 0.102
nucleic acid templated transcription GO:0097659 169 0.101
axon guidance GO:0007411 82 0.101
negative regulation of cellular process GO:0048523 239 0.100
ion transport GO:0006811 113 0.100
axon development GO:0061564 163 0.100
regulation of cell migration GO:0030334 55 0.099
mitotic cell cycle process GO:1903047 194 0.094
sex differentiation GO:0007548 909 0.094
cell projection organization GO:0030030 231 0.094
multi multicellular organism process GO:0044706 390 0.091
cell cycle GO:0007049 526 0.091
multicellular organismal aging GO:0010259 812 0.088
multicellular organismal reproductive process GO:0048609 815 0.088
cellular component movement GO:0006928 388 0.086
response to organic substance GO:0010033 131 0.083
neuron differentiation GO:0030182 217 0.083
localization of cell GO:0051674 313 0.082
organelle organization GO:0006996 783 0.081
aging GO:0007568 812 0.078
growth GO:0040007 562 0.077
nucleobase containing compound biosynthetic process GO:0034654 184 0.077
regulation of nitrogen compound metabolic process GO:0051171 222 0.076
protein localization GO:0008104 205 0.074
positive regulation of locomotion GO:0040017 42 0.073
nucleobase containing compound metabolic process GO:0006139 406 0.073
regulation of developmental growth GO:0048638 389 0.072
ion transmembrane transport GO:0034220 91 0.071
negative regulation of biological process GO:0048519 567 0.071
regulation of cellular metabolic process GO:0031323 305 0.070
head development GO:0060322 1 0.068
generation of neurons GO:0048699 235 0.068
establishment of localization in cell GO:0051649 318 0.067
regulation of cellular component movement GO:0051270 62 0.067
regulation of biological quality GO:0065008 741 0.067
single organism reproductive process GO:0044702 1196 0.067
organic cyclic compound biosynthetic process GO:1901362 195 0.066
nervous system development GO:0007399 253 0.066
cell migration GO:0016477 306 0.066
cellular component morphogenesis GO:0032989 318 0.065
membrane organization GO:0061024 135 0.065
organelle fission GO:0048285 363 0.064
biosynthetic process GO:0009058 323 0.064
regulation of developmental process GO:0050793 684 0.063
response to external stimulus GO:0009605 289 0.063
regulation of multicellular organismal process GO:0051239 726 0.063
regulation of signal transduction GO:0009966 135 0.063
cellular biosynthetic process GO:0044249 315 0.062
actin filament based process GO:0030029 191 0.062
macromolecule localization GO:0033036 771 0.062
maintenance of location GO:0051235 580 0.062
regulation of primary metabolic process GO:0080090 292 0.061
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.061
female gamete generation GO:0007292 254 0.061
cation transport GO:0006812 78 0.061
positive regulation of developmental process GO:0051094 408 0.060
sexual reproduction GO:0019953 546 0.060
positive regulation of growth GO:0045927 369 0.060
taxis GO:0042330 128 0.059
macromolecular complex subunit organization GO:0043933 320 0.058
cell death GO:0008219 547 0.057
cytoskeleton organization GO:0007010 339 0.056
death GO:0016265 547 0.056
regulation of post embryonic development GO:0048580 260 0.054
multicellular organism reproduction GO:0032504 819 0.054
body morphogenesis GO:0010171 620 0.054
regulation of nucleic acid templated transcription GO:1903506 165 0.053
gamete generation GO:0007276 461 0.053
regulation of metabolic process GO:0019222 478 0.053
regulation of rna biosynthetic process GO:2001141 165 0.053
apoptotic process GO:0006915 478 0.052
positive regulation of multicellular organismal process GO:0051240 417 0.052
anatomical structure formation involved in morphogenesis GO:0048646 250 0.051
inductive cell migration GO:0040039 145 0.050
regulation of signaling GO:0023051 172 0.050
protein metabolic process GO:0019538 422 0.050
rna biosynthetic process GO:0032774 169 0.049
cellular response to organic substance GO:0071310 119 0.049
protein complex subunit organization GO:0071822 280 0.049
lipid storage GO:0019915 565 0.049
multicellular organism growth GO:0035264 385 0.048
cellular macromolecule biosynthetic process GO:0034645 247 0.047
nucleus localization GO:0051647 55 0.047
tube morphogenesis GO:0035239 79 0.047
post embryonic organ development GO:0048569 336 0.047
striated muscle cell differentiation GO:0051146 158 0.045
negative regulation of multicellular organismal process GO:0051241 236 0.044
nucleic acid metabolic process GO:0090304 299 0.044
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.044
negative regulation of developmental process GO:0051093 227 0.044
regulation of localization GO:0032879 194 0.043
protein catabolic process GO:0030163 162 0.042
neuron projection development GO:0031175 187 0.042
cellular component assembly involved in morphogenesis GO:0010927 183 0.041
lipid localization GO:0010876 573 0.041
cuticle development GO:0042335 100 0.041
metal ion transport GO:0030001 49 0.041
positive regulation of response to stimulus GO:0048584 55 0.041
developmental growth GO:0048589 412 0.041
regulation of nematode larval development GO:0061062 260 0.041
regulation of multicellular organismal development GO:2000026 317 0.041
regulation of macromolecule metabolic process GO:0060255 421 0.040
regulation of biosynthetic process GO:0009889 189 0.040
negative regulation of metabolic process GO:0009892 240 0.040
regulation of cell motility GO:2000145 57 0.039
transcription from rna polymerase ii promoter GO:0006366 149 0.039
neuron development GO:0048666 199 0.038
regulation of gene expression GO:0010468 366 0.038
negative regulation of response to stimulus GO:0048585 73 0.037
regulation of locomotion GO:0040012 161 0.037
carbohydrate derivative metabolic process GO:1901135 141 0.037
mitotic nuclear division GO:0007067 89 0.037
axonogenesis GO:0007409 102 0.036
negative regulation of nucleic acid templated transcription GO:1903507 53 0.036
digestive tract development GO:0048565 122 0.036
regulation of gene expression epigenetic GO:0040029 163 0.035
organic substance biosynthetic process GO:1901576 323 0.035
rna metabolic process GO:0016070 228 0.035
cell surface receptor signaling pathway GO:0007166 149 0.035
regulation of cellular biosynthetic process GO:0031326 189 0.035
regulation of growth GO:0040008 409 0.035
regulation of rna metabolic process GO:0051252 173 0.035
response to chemical GO:0042221 356 0.034
regulation of organelle organization GO:0033043 164 0.034
establishment of organelle localization GO:0051656 123 0.034
chemotaxis GO:0006935 120 0.034
nuclear migration GO:0007097 54 0.034
neurological system process GO:0050877 53 0.034
protein modification process GO:0036211 207 0.034
vulval development GO:0040025 333 0.034
muscle structure development GO:0061061 191 0.034
meiotic cell cycle GO:0051321 335 0.034
synaptic transmission GO:0007268 106 0.033
locomotory behavior GO:0007626 40 0.032
cell projection assembly GO:0030031 35 0.032
regulation of reproductive process GO:2000241 66 0.032
cell recognition GO:0008037 85 0.032
apoptotic cell clearance GO:0043277 111 0.032
regulation of transcription dna templated GO:0006355 164 0.031
cytokinesis GO:0000910 80 0.031
cell projection morphogenesis GO:0048858 148 0.031
organonitrogen compound metabolic process GO:1901564 151 0.031
striated muscle cell development GO:0055002 157 0.031
pronuclear migration GO:0035046 51 0.031
cellular protein metabolic process GO:0044267 279 0.031
epithelial tube morphogenesis GO:0060562 1 0.030
response to abiotic stimulus GO:0009628 152 0.030
regulation of multicellular organism growth GO:0040014 373 0.030
establishment of nucleus localization GO:0040023 55 0.030
neuron recognition GO:0008038 83 0.030
tissue development GO:0009888 112 0.030
neuron projection morphogenesis GO:0048812 114 0.029
negative regulation of cellular metabolic process GO:0031324 95 0.029
regulation of cellular component organization GO:0051128 248 0.029
intracellular transport GO:0046907 77 0.028
positive regulation of molecular function GO:0044093 61 0.028
regulation of cell communication GO:0010646 176 0.028
macromolecule catabolic process GO:0009057 202 0.028
actomyosin structure organization GO:0031032 154 0.028
negative regulation of gene expression GO:0010629 217 0.028
muscle organ morphogenesis GO:0048644 4 0.028
response to unfolded protein GO:0006986 71 0.027
tube formation GO:0035148 2 0.027
muscle cell differentiation GO:0042692 171 0.027
transcription dna templated GO:0006351 168 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.027
positive regulation of multicellular organism growth GO:0040018 352 0.026
g protein coupled receptor signaling pathway GO:0007186 46 0.026
oogenesis GO:0048477 229 0.026
regulation of multi organism process GO:0043900 69 0.026
cell division GO:0051301 262 0.025
cellular component biogenesis GO:0044085 297 0.025
actin cytoskeleton organization GO:0030036 184 0.024
mechanosensory behavior GO:0007638 25 0.023
regulation of phosphorus metabolic process GO:0051174 81 0.023
germ cell development GO:0007281 351 0.023
cell cell signaling GO:0007267 118 0.023
digestive tract morphogenesis GO:0048546 76 0.023
chromosome segregation GO:0007059 180 0.022
regulation of cytoskeleton organization GO:0051493 41 0.022
enzyme linked receptor protein signaling pathway GO:0007167 50 0.022
cellular macromolecular complex assembly GO:0034622 184 0.022
regulation of actin filament based process GO:0032970 22 0.022
cell motility GO:0048870 313 0.022
axonal fasciculation GO:0007413 79 0.022
regulation of vulval development GO:0040028 248 0.022
regulation of ion transport GO:0043269 39 0.022
regulation of transport GO:0051049 91 0.022
macromolecule modification GO:0043412 218 0.021
myofibril assembly GO:0030239 154 0.021
response to wounding GO:0009611 4 0.021
striated muscle myosin thick filament assembly GO:0071688 138 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.021
neurogenesis GO:0022008 236 0.021
positive regulation of cell migration GO:0030335 3 0.021
negative regulation of macromolecule metabolic process GO:0010605 229 0.021
spindle localization GO:0051653 51 0.021
muscle cell development GO:0055001 158 0.021
transmembrane transport GO:0055085 110 0.021
digestive system development GO:0055123 122 0.021
phosphate containing compound metabolic process GO:0006796 232 0.021
negative regulation of transporter activity GO:0032410 3 0.020
positive regulation of developmental growth GO:0048639 354 0.020
negative regulation of ion transmembrane transport GO:0034766 3 0.020
cell morphogenesis GO:0000902 163 0.020
small molecule metabolic process GO:0044281 186 0.019
cell morphogenesis involved in differentiation GO:0000904 112 0.019
regulation of behavior GO:0050795 97 0.019
nucleoside phosphate metabolic process GO:0006753 108 0.019
cellular protein modification process GO:0006464 207 0.019
response to other organism GO:0051707 101 0.019
cellular protein complex assembly GO:0043623 178 0.019
regulation of apoptotic signaling pathway GO:2001233 1 0.019
cellular response to stress GO:0033554 162 0.019
phagocytosis GO:0006909 115 0.019
macromolecular complex assembly GO:0065003 193 0.018
regulation of cell cycle GO:0051726 194 0.018
oxoacid metabolic process GO:0043436 47 0.018
nucleobase containing small molecule metabolic process GO:0055086 115 0.018
response to external biotic stimulus GO:0043207 101 0.018
embryonic morphogenesis GO:0048598 152 0.018
pattern specification process GO:0007389 59 0.018
sensory perception GO:0007600 27 0.018
protein complex assembly GO:0006461 186 0.018
meiotic nuclear division GO:0007126 300 0.017
response to oxygen containing compound GO:1901700 44 0.017
regulation of synaptic transmission GO:0050804 34 0.017
response to mechanical stimulus GO:0009612 28 0.017
response to topologically incorrect protein GO:0035966 82 0.017
cellular catabolic process GO:0044248 199 0.017
macromolecule biosynthetic process GO:0009059 250 0.017
sensory organ morphogenesis GO:0090596 2 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
regulation of cell cycle process GO:0010564 145 0.017
phagocytosis engulfment GO:0006911 98 0.017
establishment of protein localization to membrane GO:0090150 3 0.016
cellular amino acid metabolic process GO:0006520 15 0.016
carboxylic acid metabolic process GO:0019752 34 0.016
regulation of striated muscle contraction GO:0006942 4 0.016
engulfment of apoptotic cell GO:0043652 94 0.016
regulation of catalytic activity GO:0050790 78 0.016
membrane invagination GO:0010324 98 0.016
nucleotide sugar metabolic process GO:0009225 6 0.016
myosin filament organization GO:0031033 138 0.016
monovalent inorganic cation transport GO:0015672 33 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.015
organelle assembly GO:0070925 214 0.015
regulation of mitotic cell cycle GO:0007346 76 0.015
regulation of cell differentiation GO:0045595 81 0.015
single organism intracellular transport GO:1902582 70 0.015
meiotic chromosome segregation GO:0045132 139 0.015
regulation of cell development GO:0060284 49 0.015
myosin filament assembly GO:0031034 138 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
organic substance catabolic process GO:1901575 294 0.015
regulation of molecular function GO:0065009 89 0.015
regulation of cell division GO:0051302 142 0.014
single organism biosynthetic process GO:0044711 91 0.014
regulation of anatomical structure morphogenesis GO:0022603 51 0.014
cell type specific apoptotic process GO:0097285 4 0.014
gastrulation GO:0007369 58 0.014
negative regulation of cellular component organization GO:0051129 33 0.014
positive regulation of cellular metabolic process GO:0031325 178 0.014
signal transduction GO:0007165 317 0.013
negative regulation of biosynthetic process GO:0009890 65 0.013
positive regulation of cell communication GO:0010647 69 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.013
spindle organization GO:0007051 92 0.013
negative regulation of transmembrane transport GO:0034763 3 0.013
cellular response to unfolded protein GO:0034620 71 0.013
cognition GO:0050890 27 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
positive regulation of signaling GO:0023056 66 0.013
excretion GO:0007588 49 0.013
regulation of cell morphogenesis GO:0022604 40 0.013
cation transmembrane transport GO:0098655 59 0.013
regulation of oviposition GO:0046662 43 0.013
regulation of nucleotide metabolic process GO:0006140 37 0.013
microtubule based process GO:0007017 182 0.012
amine metabolic process GO:0009308 15 0.012
single organism catabolic process GO:0044712 129 0.012
response to acid chemical GO:0001101 4 0.012
organelle localization GO:0051640 127 0.012
catabolic process GO:0009056 318 0.012
adult behavior GO:0030534 3 0.012
regulation of phosphate metabolic process GO:0019220 81 0.012
response to oxygen levels GO:0070482 22 0.012
nematode male tail tip morphogenesis GO:0045138 77 0.012
protein complex biogenesis GO:0070271 186 0.012
skeletal muscle organ development GO:0060538 3 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
neuron projection extension GO:1990138 37 0.011
cellular response to nitrogen compound GO:1901699 24 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.011
protein phosphorylation GO:0006468 85 0.011
negative regulation of cellular biosynthetic process GO:0031327 65 0.011
response to oxidative stress GO:0006979 42 0.011
neuron projection guidance GO:0097485 82 0.011
regulation of cell proliferation GO:0042127 105 0.011
negative regulation of gene expression epigenetic GO:0045814 2 0.011
negative regulation of rna biosynthetic process GO:1902679 53 0.011
nucleotide metabolic process GO:0009117 108 0.011
pharyngeal pumping GO:0043050 58 0.011
response to inorganic substance GO:0010035 50 0.011
peptidyl amino acid modification GO:0018193 58 0.011
response to biotic stimulus GO:0009607 101 0.011
molting cycle GO:0042303 281 0.011
regulation of cytoplasmic transport GO:1903649 3 0.011
regulation of nuclear division GO:0051783 115 0.011
epithelium development GO:0060429 68 0.011
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.010
tube development GO:0035295 126 0.010
endomembrane system organization GO:0010256 22 0.010
mitotic sister chromatid segregation GO:0000070 38 0.010
positive regulation of cellular process GO:0048522 332 0.010

hum-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
myopathy DOID:423 0 0.060
muscular disease DOID:0080000 0 0.060
heart disease DOID:114 0 0.060
cardiomyopathy DOID:0050700 0 0.060
cardiovascular system disease DOID:1287 0 0.060
musculoskeletal system disease DOID:17 0 0.060
muscle tissue disease DOID:66 0 0.060
nervous system disease DOID:863 0 0.011