Caenorhabditis elegans

10 known processes

idh-1 (CELE_F59B8.2)

Protein IDH-1

idh-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.639
embryo development GO:0009790 3052 0.625
post embryonic development GO:0009791 2152 0.547
establishment of localization GO:0051234 1171 0.333
organ development GO:0048513 1102 0.329
cellular localization GO:0051641 360 0.319
reproductive system development GO:0061458 850 0.307
vesicle mediated transport GO:0016192 852 0.287
receptor mediated endocytosis GO:0006898 715 0.252
regulation of developmental process GO:0050793 684 0.234
endocytosis GO:0006897 819 0.234
sex differentiation GO:0007548 909 0.225
multicellular organism reproduction GO:0032504 819 0.221
response to chemical GO:0042221 356 0.220
determination of adult lifespan GO:0008340 812 0.207
single organism localization GO:1902578 518 0.203
multicellular organismal aging GO:0010259 812 0.202
organelle organization GO:0006996 783 0.198
regulation of gene expression GO:0010468 366 0.197
cellular component movement GO:0006928 388 0.197
aging GO:0007568 812 0.183
transport GO:0006810 1093 0.165
reproductive structure development GO:0048608 850 0.162
single organism organelle organization GO:1902589 501 0.161
development of primary sexual characteristics GO:0045137 840 0.158
muscle structure development GO:0061061 191 0.155
single organism transport GO:0044765 447 0.154
gamete generation GO:0007276 461 0.149
growth GO:0040007 562 0.145
gonad development GO:0008406 840 0.140
negative regulation of biological process GO:0048519 567 0.140
regulation of metabolic process GO:0019222 478 0.139
single organism reproductive process GO:0044702 1196 0.138
macromolecule localization GO:0033036 771 0.132
positive regulation of cellular process GO:0048522 332 0.129
developmental process involved in reproduction GO:0003006 1165 0.126
regulation of biological quality GO:0065008 741 0.121
cellular biosynthetic process GO:0044249 315 0.116
regulation of macromolecule metabolic process GO:0060255 421 0.115
gene expression GO:0010467 412 0.113
cell migration GO:0016477 306 0.110
locomotion GO:0040011 1634 0.107
molting cycle GO:0042303 281 0.105
tissue development GO:0009888 112 0.100
epithelium development GO:0060429 68 0.099
multicellular organismal reproductive process GO:0048609 815 0.098
multi organism reproductive process GO:0044703 867 0.096
secretion by cell GO:0032940 138 0.094
positive regulation of developmental process GO:0051094 408 0.094
macromolecular complex subunit organization GO:0043933 320 0.092
protein metabolic process GO:0019538 422 0.089
regulation of multicellular organismal process GO:0051239 726 0.087
striated muscle cell differentiation GO:0051146 158 0.084
establishment of localization in cell GO:0051649 318 0.084
cellular component biogenesis GO:0044085 297 0.083
signal transduction GO:0007165 317 0.082
response to external stimulus GO:0009605 289 0.082
lipid localization GO:0010876 573 0.080
macromolecule biosynthetic process GO:0009059 250 0.080
cell motility GO:0048870 313 0.079
cell development GO:0048468 696 0.078
regulation of developmental growth GO:0048638 389 0.078
positive regulation of multicellular organismal process GO:0051240 417 0.077
protein complex subunit organization GO:0071822 280 0.077
organ morphogenesis GO:0009887 67 0.076
genitalia development GO:0048806 741 0.074
maintenance of location GO:0051235 580 0.074
regulation of growth GO:0040008 409 0.074
regulation of multicellular organism growth GO:0040014 373 0.073
positive regulation of multicellular organism growth GO:0040018 352 0.072
regulation of cellular component organization GO:0051128 248 0.070
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.070
response to abiotic stimulus GO:0009628 152 0.068
sexual reproduction GO:0019953 546 0.068
cell death GO:0008219 547 0.068
body morphogenesis GO:0010171 620 0.067
cellular protein complex assembly GO:0043623 178 0.067
cellular component assembly GO:0022607 293 0.066
cell part morphogenesis GO:0032990 152 0.066
multicellular organism growth GO:0035264 385 0.065
transcription dna templated GO:0006351 168 0.062
regulation of macromolecule biosynthetic process GO:0010556 189 0.061
localization of cell GO:0051674 313 0.061
cytoskeleton organization GO:0007010 339 0.061
lipid storage GO:0019915 565 0.059
biosynthetic process GO:0009058 323 0.059
hermaphrodite genitalia development GO:0040035 734 0.059
death GO:0016265 547 0.058
positive regulation of growth GO:0045927 369 0.058
developmental growth GO:0048589 412 0.058
negative regulation of gene expression GO:0010629 217 0.058
tube development GO:0035295 126 0.058
cellular macromolecule biosynthetic process GO:0034645 247 0.058
cellular nitrogen compound biosynthetic process GO:0044271 192 0.057
secretion GO:0046903 147 0.057
nucleobase containing compound metabolic process GO:0006139 406 0.056
positive regulation of cellular metabolic process GO:0031325 178 0.056
oxoacid metabolic process GO:0043436 47 0.056
Human
cell cycle GO:0007049 526 0.055
striated muscle cell development GO:0055002 157 0.055
anatomical structure formation involved in morphogenesis GO:0048646 250 0.054
organelle assembly GO:0070925 214 0.054
defense response GO:0006952 296 0.054
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.054
regulation of primary metabolic process GO:0080090 292 0.054
cellular component morphogenesis GO:0032989 318 0.054
positive regulation of macromolecule metabolic process GO:0010604 149 0.052
vulval development GO:0040025 333 0.051
signaling GO:0023052 401 0.049
positive regulation of developmental growth GO:0048639 354 0.048
regulation of multicellular organismal development GO:2000026 317 0.047
protein complex assembly GO:0006461 186 0.046
actin cytoskeleton organization GO:0030036 184 0.046
multi multicellular organism process GO:0044706 390 0.046
fertilization GO:0009566 63 0.045
phosphorus metabolic process GO:0006793 232 0.045
aromatic compound biosynthetic process GO:0019438 192 0.045
programmed cell death GO:0012501 500 0.044
organic substance catabolic process GO:1901575 294 0.044
cellular response to chemical stimulus GO:0070887 129 0.043
macromolecular complex assembly GO:0065003 193 0.042
regulation of biosynthetic process GO:0009889 189 0.042
system process GO:0003008 136 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.041
positive regulation of metabolic process GO:0009893 187 0.040
behavior GO:0007610 527 0.039
cellular protein metabolic process GO:0044267 279 0.038
female gamete generation GO:0007292 254 0.038
small molecule biosynthetic process GO:0044283 38 0.038
regulation of rna metabolic process GO:0051252 173 0.038
catabolic process GO:0009056 318 0.037
negative regulation of macromolecule metabolic process GO:0010605 229 0.037
multi organism reproductive behavior GO:0044705 387 0.037
regulation of localization GO:0032879 194 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.035
cellular macromolecular complex assembly GO:0034622 184 0.035
regulation of transcription dna templated GO:0006355 164 0.034
establishment or maintenance of cell polarity GO:0007163 63 0.034
ion transport GO:0006811 113 0.034
protein complex biogenesis GO:0070271 186 0.033
organic substance biosynthetic process GO:1901576 323 0.033
small molecule metabolic process GO:0044281 186 0.033
Human
regulation of cellular ketone metabolic process GO:0010565 3 0.032
regulation of signaling GO:0023051 172 0.032
germ cell development GO:0007281 351 0.032
regulation of response to stimulus GO:0048583 243 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.031
organelle localization GO:0051640 127 0.030
lipid metabolic process GO:0006629 77 0.029
cellular component assembly involved in morphogenesis GO:0010927 183 0.029
positive regulation of transcription dna templated GO:0045893 102 0.028
muscle cell differentiation GO:0042692 171 0.028
tissue morphogenesis GO:0048729 65 0.028
positive regulation of biosynthetic process GO:0009891 109 0.028
protein localization GO:0008104 205 0.028
regulation of lipid metabolic process GO:0019216 4 0.027
regulation of rna biosynthetic process GO:2001141 165 0.027
positive regulation of rna metabolic process GO:0051254 103 0.027
muscle tissue development GO:0060537 1 0.027
positive regulation of rna biosynthetic process GO:1902680 102 0.027
myosin filament assembly GO:0031034 138 0.026
response to osmotic stress GO:0006970 29 0.026
oogenesis GO:0048477 229 0.026
muscle cell development GO:0055001 158 0.026
tube morphogenesis GO:0035239 79 0.026
collagen and cuticulin based cuticle development GO:0040002 99 0.026
regulation of vulval development GO:0040028 248 0.025
intracellular receptor signaling pathway GO:0030522 2 0.025
response to wounding GO:0009611 4 0.025
cellular ketone metabolic process GO:0042180 14 0.025
negative regulation of metabolic process GO:0009892 240 0.025
cell surface receptor signaling pathway GO:0007166 149 0.025
reproductive behavior GO:0019098 387 0.025
regulation of gene expression epigenetic GO:0040029 163 0.025
single organism signaling GO:0044700 401 0.024
multi organism behavior GO:0051705 389 0.024
post embryonic organ development GO:0048569 336 0.024
regulation of cellular metabolic process GO:0031323 305 0.024
rna biosynthetic process GO:0032774 169 0.023
gene silencing by rna GO:0031047 143 0.023
actin filament based process GO:0030029 191 0.023
organic acid metabolic process GO:0006082 47 0.023
Human
multicellular organismal reproductive behavior GO:0033057 384 0.023
apoptotic process GO:0006915 478 0.023
cellular amine metabolic process GO:0044106 15 0.023
nucleic acid templated transcription GO:0097659 169 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.022
homeostatic process GO:0042592 51 0.022
macromolecule modification GO:0043412 218 0.022
regulation of cellular biosynthetic process GO:0031326 189 0.022
regulation of cell migration GO:0030334 55 0.021
regulation of nematode larval development GO:0061062 260 0.021
striated muscle myosin thick filament assembly GO:0071688 138 0.021
meiotic cell cycle GO:0051321 335 0.021
negative regulation of developmental process GO:0051093 227 0.021
oviposition GO:0018991 364 0.021
digestive tract development GO:0048565 122 0.021
establishment of organelle localization GO:0051656 123 0.021
meiotic cell cycle process GO:1903046 170 0.020
rna interference GO:0016246 137 0.020
oxidation reduction process GO:0055114 59 0.020
Human
immune response GO:0006955 192 0.020
cellular protein localization GO:0034613 75 0.020
gene silencing GO:0016458 143 0.020
protein catabolic process GO:0030163 162 0.020
regulation of syncytium formation by plasma membrane fusion GO:0060142 4 0.019
transcription from rna polymerase ii promoter GO:0006366 149 0.019
digestive tract morphogenesis GO:0048546 76 0.019
digestive system development GO:0055123 122 0.019
actomyosin structure organization GO:0031032 154 0.018
nervous system development GO:0007399 253 0.018
excretion GO:0007588 49 0.018
organelle fission GO:0048285 363 0.018
cellular response to unfolded protein GO:0034620 71 0.018
regulation of nitrogen compound metabolic process GO:0051171 222 0.018
membrane organization GO:0061024 135 0.018
posttranscriptional gene silencing by rna GO:0035194 143 0.018
ceramide metabolic process GO:0006672 2 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.018
regulation of cell communication GO:0010646 176 0.017
myosin filament organization GO:0031033 138 0.017
regulation of post embryonic development GO:0048580 260 0.017
lipid biosynthetic process GO:0008610 28 0.017
posttranscriptional gene silencing GO:0016441 143 0.017
positive regulation of programmed cell death GO:0043068 27 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.017
nucleobase containing compound biosynthetic process GO:0034654 184 0.017
phosphorylation GO:0016310 116 0.017
cell cell signaling GO:0007267 118 0.017
posttranscriptional regulation of gene expression GO:0010608 166 0.017
nucleic acid metabolic process GO:0090304 299 0.017
monocarboxylic acid metabolic process GO:0032787 22 0.017
amine metabolic process GO:0009308 15 0.017
microtubule based process GO:0007017 182 0.017
phosphate containing compound metabolic process GO:0006796 232 0.016
regulation of phosphate metabolic process GO:0019220 81 0.016
ribonucleotide catabolic process GO:0009261 75 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.016
regulation of behavior GO:0050795 97 0.016
organic substance transport GO:0071702 113 0.016
macromolecule catabolic process GO:0009057 202 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.016
positive regulation of cellular biosynthetic process GO:0031328 109 0.016
cell projection organization GO:0030030 231 0.016
negative regulation of multicellular organismal process GO:0051241 236 0.016
cell cycle process GO:0022402 482 0.016
negative regulation of cellular biosynthetic process GO:0031327 65 0.015
regulation of signal transduction GO:0009966 135 0.015
negative regulation of rna biosynthetic process GO:1902679 53 0.015
dauer larval development GO:0040024 92 0.015
myofibril assembly GO:0030239 154 0.015
regeneration GO:0031099 4 0.015
heterocycle biosynthetic process GO:0018130 187 0.015
single organism catabolic process GO:0044712 129 0.015
negative regulation of transcription dna templated GO:0045892 53 0.015
nucleus localization GO:0051647 55 0.015
inductive cell migration GO:0040039 145 0.015
negative regulation of cellular component organization GO:0051129 33 0.015
positive regulation of gene expression GO:0010628 112 0.015
single fertilization GO:0007338 61 0.015
regulation of nucleic acid templated transcription GO:1903506 165 0.015
positive regulation of nucleic acid templated transcription GO:1903508 102 0.015
adult behavior GO:0030534 3 0.015
negative regulation of nucleic acid templated transcription GO:1903507 53 0.015
response to external biotic stimulus GO:0043207 101 0.014
negative regulation of cellular process GO:0048523 239 0.014
cellular lipid metabolic process GO:0044255 40 0.014
organophosphate metabolic process GO:0019637 125 0.014
cuticle development GO:0042335 100 0.014
single organism biosynthetic process GO:0044711 91 0.014
rna metabolic process GO:0016070 228 0.014
response to organic substance GO:0010033 131 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.014
negative regulation of nematode larval development GO:0061064 208 0.013
cell substrate adhesion GO:0031589 1 0.013
sensory organ morphogenesis GO:0090596 2 0.013
organonitrogen compound metabolic process GO:1901564 151 0.013
regulation of locomotion GO:0040012 161 0.013
endoplasmic reticulum unfolded protein response GO:0030968 66 0.013
embryonic morphogenesis GO:0048598 152 0.013
regulation of lipid biosynthetic process GO:0046890 1 0.013
organonitrogen compound biosynthetic process GO:1901566 44 0.013
neurogenesis GO:0022008 236 0.013
mitotic cell cycle process GO:1903047 194 0.013
cell division GO:0051301 262 0.012
meiotic chromosome segregation GO:0045132 139 0.012
response to topologically incorrect protein GO:0035966 82 0.012
spermatogenesis GO:0007283 41 0.012
mitochondrion organization GO:0007005 20 0.012
apoptotic cell clearance GO:0043277 111 0.012
nucleoside metabolic process GO:0009116 99 0.012
chromosome segregation GO:0007059 180 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
Human
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.012
establishment of cell polarity GO:0030010 46 0.011
regulation of cell division GO:0051302 142 0.011
adult locomotory behavior GO:0008344 1 0.011
negative regulation of biosynthetic process GO:0009890 65 0.011
phagocytosis engulfment GO:0006911 98 0.011
response to biotic stimulus GO:0009607 101 0.011
head development GO:0060322 1 0.011
neuron recognition GO:0008038 83 0.011
neuron differentiation GO:0030182 217 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
chromosome organization GO:0051276 104 0.011
cellular response to organic substance GO:0071310 119 0.011
lipid oxidation GO:0034440 1 0.011
intracellular signal transduction GO:0035556 96 0.011
synaptic transmission GO:0007268 106 0.011
purine nucleoside metabolic process GO:0042278 92 0.011
cellular amino acid metabolic process GO:0006520 15 0.010
eating behavior GO:0042755 59 0.010
negative regulation of vulval development GO:0040027 206 0.010
negative regulation of rna metabolic process GO:0051253 53 0.010
protein oligomerization GO:0051259 4 0.010
establishment of nucleus localization GO:0040023 55 0.010
anion transport GO:0006820 30 0.010
epithelial cell proliferation GO:0050673 1 0.010
phagocytosis GO:0006909 115 0.010
cellular macromolecule localization GO:0070727 75 0.010

idh-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.026
Human
cancer DOID:162 0 0.012
Human
organ system cancer DOID:0050686 0 0.012
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011