Caenorhabditis elegans

57 known processes

mec-15 (CELE_T01E8.4)

Protein MEC-15

mec-15 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.461
embryo development ending in birth or egg hatching GO:0009792 2992 0.407
sex differentiation GO:0007548 909 0.389
embryo development GO:0009790 3052 0.358
reproductive system development GO:0061458 850 0.347
aging GO:0007568 812 0.272
organ development GO:0048513 1102 0.267
transport GO:0006810 1093 0.247
regulation of gene expression GO:0010468 366 0.242
multicellular organismal aging GO:0010259 812 0.239
developmental process involved in reproduction GO:0003006 1165 0.231
receptor mediated endocytosis GO:0006898 715 0.212
multicellular organism reproduction GO:0032504 819 0.175
genitalia development GO:0048806 741 0.175
development of primary sexual characteristics GO:0045137 840 0.159
gonad development GO:0008406 840 0.154
gene expression GO:0010467 412 0.145
multi organism reproductive process GO:0044703 867 0.143
single organism reproductive process GO:0044702 1196 0.143
reproductive structure development GO:0048608 850 0.132
locomotion GO:0040011 1634 0.128
gamete generation GO:0007276 461 0.127
cell death GO:0008219 547 0.125
hermaphrodite genitalia development GO:0040035 734 0.116
determination of adult lifespan GO:0008340 812 0.111
positive regulation of cellular process GO:0048522 332 0.111
macromolecule biosynthetic process GO:0009059 250 0.111
sexual reproduction GO:0019953 546 0.109
vesicle mediated transport GO:0016192 852 0.107
germ cell development GO:0007281 351 0.105
regulation of metabolic process GO:0019222 478 0.103
post embryonic organ development GO:0048569 336 0.099
death GO:0016265 547 0.094
multicellular organismal reproductive process GO:0048609 815 0.093
negative regulation of macromolecule metabolic process GO:0010605 229 0.090
aromatic compound biosynthetic process GO:0019438 192 0.087
regulation of macromolecule metabolic process GO:0060255 421 0.085
cellular nitrogen compound biosynthetic process GO:0044271 192 0.080
endocytosis GO:0006897 819 0.080
cell cycle GO:0007049 526 0.075
behavior GO:0007610 527 0.072
cytoskeleton organization GO:0007010 339 0.066
body morphogenesis GO:0010171 620 0.066
protein metabolic process GO:0019538 422 0.065
cell development GO:0048468 696 0.061
negative regulation of gene expression GO:0010629 217 0.061
programmed cell death GO:0012501 500 0.060
multi organism behavior GO:0051705 389 0.060
regulation of rna metabolic process GO:0051252 173 0.058
negative regulation of biological process GO:0048519 567 0.057
posttranscriptional regulation of gene expression GO:0010608 166 0.057
oocyte construction GO:0007308 2 0.056
regulation of biosynthetic process GO:0009889 189 0.056
rna metabolic process GO:0016070 228 0.056
multicellular organismal reproductive behavior GO:0033057 384 0.056
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.056
multi organism reproductive behavior GO:0044705 387 0.056
regulation of gene expression epigenetic GO:0040029 163 0.056
nucleobase containing compound biosynthetic process GO:0034654 184 0.055
apoptotic process GO:0006915 478 0.054
lipid storage GO:0019915 565 0.053
organic substance biosynthetic process GO:1901576 323 0.053
protein deubiquitination GO:0016579 2 0.052
multi multicellular organism process GO:0044706 390 0.052
regulation of nematode larval development GO:0061062 260 0.052
lipid localization GO:0010876 573 0.051
gene silencing by rna GO:0031047 143 0.050
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.050
regulation of biological quality GO:0065008 741 0.049
organonitrogen compound metabolic process GO:1901564 151 0.049
maintenance of location GO:0051235 580 0.049
organelle fission GO:0048285 363 0.048
cellular protein metabolic process GO:0044267 279 0.048
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.046
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.046
regulation of vulval development GO:0040028 248 0.045
regulation of multicellular organismal process GO:0051239 726 0.044
proteolysis GO:0006508 61 0.043
oviposition GO:0018991 364 0.043
carbohydrate derivative metabolic process GO:1901135 141 0.042
meiotic nuclear division GO:0007126 300 0.042
macromolecule localization GO:0033036 771 0.041
phosphorus metabolic process GO:0006793 232 0.041
vulval development GO:0040025 333 0.041
gene silencing GO:0016458 143 0.040
cellular macromolecule biosynthetic process GO:0034645 247 0.040
transcription dna templated GO:0006351 168 0.039
regulation of developmental process GO:0050793 684 0.037
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.037
regulation of primary metabolic process GO:0080090 292 0.037
regulation of cellular metabolic process GO:0031323 305 0.036
organelle organization GO:0006996 783 0.036
regulation of post embryonic development GO:0048580 260 0.036
rna interference GO:0016246 137 0.035
organic cyclic compound biosynthetic process GO:1901362 195 0.035
regulation of cellular component organization GO:0051128 248 0.035
regulation of cellular biosynthetic process GO:0031326 189 0.035
single organism organelle organization GO:1902589 501 0.034
cellular biosynthetic process GO:0044249 315 0.033
regulation of macromolecule biosynthetic process GO:0010556 189 0.033
secretion by cell GO:0032940 138 0.032
posttranscriptional gene silencing by rna GO:0035194 143 0.032
positive regulation of chromosome organization GO:2001252 2 0.031
macromolecular complex subunit organization GO:0043933 320 0.031
regulation of rna biosynthetic process GO:2001141 165 0.031
positive regulation of gene expression GO:0010628 112 0.031
biosynthetic process GO:0009058 323 0.031
positive regulation of rna metabolic process GO:0051254 103 0.030
growth GO:0040007 562 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.030
posttranscriptional gene silencing GO:0016441 143 0.029
macromolecule modification GO:0043412 218 0.029
positive regulation of multicellular organismal process GO:0051240 417 0.027
positive regulation of rna biosynthetic process GO:1902680 102 0.027
positive regulation of developmental process GO:0051094 408 0.027
establishment of localization GO:0051234 1171 0.027
negative regulation of cellular metabolic process GO:0031324 95 0.026
negative regulation of metabolic process GO:0009892 240 0.026
rna biosynthetic process GO:0032774 169 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.025
negative regulation of multicellular organismal process GO:0051241 236 0.025
regulation of nucleic acid templated transcription GO:1903506 165 0.024
protein modification process GO:0036211 207 0.024
negative regulation of vulval development GO:0040027 206 0.023
muscle structure development GO:0061061 191 0.023
regulation of cell division GO:0051302 142 0.023
cellular protein complex assembly GO:0043623 178 0.023
cellular component morphogenesis GO:0032989 318 0.023
reproductive behavior GO:0019098 387 0.022
regulation of protein metabolic process GO:0051246 81 0.022
positive regulation of nucleic acid templated transcription GO:1903508 102 0.021
cellular macromolecular complex assembly GO:0034622 184 0.021
negative regulation of developmental process GO:0051093 227 0.020
organic cyclic compound catabolic process GO:1901361 119 0.020
modification dependent macromolecule catabolic process GO:0043632 32 0.020
female gamete generation GO:0007292 254 0.020
cellular nitrogen compound catabolic process GO:0044270 119 0.020
positive regulation of biosynthetic process GO:0009891 109 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.019
regulation of multicellular organismal development GO:2000026 317 0.019
aromatic compound catabolic process GO:0019439 116 0.019
chromosome organization GO:0051276 104 0.019
positive regulation of cellular protein catabolic process GO:1903364 3 0.019
nucleobase containing compound metabolic process GO:0006139 406 0.019
negative regulation of post embryonic development GO:0048581 208 0.019
hermaphrodite germ line sex determination GO:0040021 48 0.018
establishment of mitotic spindle localization GO:0040001 41 0.018
negative regulation of nematode larval development GO:0061064 208 0.018
cell division GO:0051301 262 0.018
cellular component movement GO:0006928 388 0.018
cellular component biogenesis GO:0044085 297 0.017
localization of cell GO:0051674 313 0.017
cellular protein modification process GO:0006464 207 0.017
regulation of organelle organization GO:0033043 164 0.017
regulation of localization GO:0032879 194 0.016
positive regulation of metabolic process GO:0009893 187 0.016
positive regulation of cellular metabolic process GO:0031325 178 0.016
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.016
meiotic cell cycle GO:0051321 335 0.016
regulation of growth GO:0040008 409 0.016
sex determination GO:0007530 60 0.015
small molecule metabolic process GO:0044281 186 0.015
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.014
nucleic acid metabolic process GO:0090304 299 0.014
positive regulation of intracellular signal transduction GO:1902533 24 0.014
regulation of multicellular organism growth GO:0040014 373 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
oogenesis GO:0048477 229 0.014
protein complex subunit organization GO:0071822 280 0.014
glycosyl compound metabolic process GO:1901657 100 0.014
cellular macromolecule catabolic process GO:0044265 73 0.014
cellular response to abiotic stimulus GO:0071214 4 0.013
response to other organism GO:0051707 101 0.013
regulation of cell communication GO:0010646 176 0.013
catabolic process GO:0009056 318 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.013
rna localization GO:0006403 3 0.013
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 1 0.013
myosin filament organization GO:0031033 138 0.012
regulation of cell cycle GO:0051726 194 0.012
ubiquitin dependent protein catabolic process GO:0006511 32 0.012
germ line sex determination GO:0018992 51 0.012
cell cycle process GO:0022402 482 0.012
protein complex biogenesis GO:0070271 186 0.012
positive regulation of multicellular organism growth GO:0040018 352 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 5 0.012
single organism transport GO:0044765 447 0.012
intraspecies interaction between organisms GO:0051703 3 0.011
muscle cell development GO:0055001 158 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
organic substance catabolic process GO:1901575 294 0.011
tube development GO:0035295 126 0.011
establishment of localization in cell GO:0051649 318 0.011
cellular component assembly involved in morphogenesis GO:0010927 183 0.011
single organism intracellular transport GO:1902582 70 0.011
phosphate containing compound metabolic process GO:0006796 232 0.011
dna templated transcription initiation GO:0006352 3 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
positive regulation of growth GO:0045927 369 0.010
regulation of chromatin modification GO:1903308 2 0.010
positive regulation of transcription dna templated GO:0045893 102 0.010
response to external biotic stimulus GO:0043207 101 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.010

mec-15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.011