Caenorhabditis elegans

70 known processes

npp-9 (CELE_F59A2.1)

Protein NPP-9

npp-9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.956
multicellular organism reproduction GO:0032504 819 0.755
post embryonic development GO:0009791 2152 0.729
embryo development GO:0009790 3052 0.643
gamete generation GO:0007276 461 0.541
organ development GO:0048513 1102 0.537
locomotion GO:0040011 1634 0.507
sexual reproduction GO:0019953 546 0.466
cytoskeleton organization GO:0007010 339 0.463
multicellular organismal reproductive process GO:0048609 815 0.428
developmental process involved in reproduction GO:0003006 1165 0.412
sex differentiation GO:0007548 909 0.374
reproductive system development GO:0061458 850 0.352
cell migration GO:0016477 306 0.343
single fertilization GO:0007338 61 0.340
aromatic compound biosynthetic process GO:0019438 192 0.324
mrna metabolic process GO:0016071 31 0.324
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.308
single organism signaling GO:0044700 401 0.296
Fly
hermaphrodite genitalia development GO:0040035 734 0.291
protein complex subunit organization GO:0071822 280 0.265
multi organism reproductive process GO:0044703 867 0.261
cellular component morphogenesis GO:0032989 318 0.254
multicellular organismal reproductive behavior GO:0033057 384 0.251
regulation of macromolecule metabolic process GO:0060255 421 0.240
cell cycle GO:0007049 526 0.235
homeostatic process GO:0042592 51 0.233
Mouse
germ cell development GO:0007281 351 0.230
cellular macromolecule biosynthetic process GO:0034645 247 0.230
development of primary sexual characteristics GO:0045137 840 0.223
regulation of rna metabolic process GO:0051252 173 0.220
gonad development GO:0008406 840 0.219
body morphogenesis GO:0010171 620 0.216
regulation of nematode larval development GO:0061062 260 0.208
organelle organization GO:0006996 783 0.199
catabolic process GO:0009056 318 0.194
reproductive structure development GO:0048608 850 0.192
vulval development GO:0040025 333 0.188
receptor mediated endocytosis GO:0006898 715 0.187
cellular localization GO:0051641 360 0.179
Fly
female gamete generation GO:0007292 254 0.175
macromolecule catabolic process GO:0009057 202 0.174
cell death GO:0008219 547 0.172
oogenesis GO:0048477 229 0.171
tissue development GO:0009888 112 0.170
apoptotic process GO:0006915 478 0.168
death GO:0016265 547 0.161
aging GO:0007568 812 0.156
purine ribonucleotide catabolic process GO:0009154 75 0.156
meiotic nuclear division GO:0007126 300 0.155
actin cytoskeleton organization GO:0030036 184 0.150
gene expression GO:0010467 412 0.148
transport GO:0006810 1093 0.141
Fly
macromolecular complex assembly GO:0065003 193 0.139
microtubule based process GO:0007017 182 0.138
cellular protein metabolic process GO:0044267 279 0.137
Human
oviposition GO:0018991 364 0.136
organic substance biosynthetic process GO:1901576 323 0.135
Mouse
negative regulation of vulval development GO:0040027 206 0.134
single organism transport GO:0044765 447 0.134
Fly
regulation of transcription dna templated GO:0006355 164 0.131
cell development GO:0048468 696 0.130
generation of neurons GO:0048699 235 0.129
multi organism reproductive behavior GO:0044705 387 0.129
macromolecule modification GO:0043412 218 0.124
Human
meiotic cell cycle GO:0051321 335 0.116
cellular response to dna damage stimulus GO:0006974 41 0.115
cell fate commitment GO:0045165 139 0.114
neuron projection development GO:0031175 187 0.113
small molecule metabolic process GO:0044281 186 0.112
Mouse
nucleic acid metabolic process GO:0090304 299 0.111
organonitrogen compound metabolic process GO:1901564 151 0.109
regulation of multicellular organismal process GO:0051239 726 0.106
growth GO:0040007 562 0.104
signal transduction GO:0007165 317 0.104
Fly
purine nucleoside triphosphate catabolic process GO:0009146 72 0.103
cell motility GO:0048870 313 0.103
organic cyclic compound biosynthetic process GO:1901362 195 0.103
nucleobase containing compound metabolic process GO:0006139 406 0.103
post embryonic organ development GO:0048569 336 0.101
cellular catabolic process GO:0044248 199 0.100
purine nucleoside triphosphate metabolic process GO:0009144 87 0.100
single organism reproductive process GO:0044702 1196 0.099
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.098
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.098
regulation of vulval development GO:0040028 248 0.098
vesicle mediated transport GO:0016192 852 0.098
oocyte construction GO:0007308 2 0.097
biosynthetic process GO:0009058 323 0.096
Mouse
intracellular transport GO:0046907 77 0.096
Fly
nucleotide catabolic process GO:0009166 77 0.096
programmed cell death GO:0012501 500 0.093
heterocycle biosynthetic process GO:0018130 187 0.093
regulation of nucleic acid templated transcription GO:1903506 165 0.091
single organism intracellular transport GO:1902582 70 0.091
Fly
protein metabolic process GO:0019538 422 0.089
Human
genitalia development GO:0048806 741 0.088
regulation of meiotic cell cycle GO:0051445 136 0.087
single organism organelle organization GO:1902589 501 0.086
molting cycle GO:0042303 281 0.086
cellular macromolecule localization GO:0070727 75 0.084
Fly
fertilization GO:0009566 63 0.084
oocyte differentiation GO:0009994 45 0.083
single organism localization GO:1902578 518 0.082
Fly
organonitrogen compound catabolic process GO:1901565 90 0.082
positive regulation of developmental process GO:0051094 408 0.081
protein complex biogenesis GO:0070271 186 0.081
cell morphogenesis involved in differentiation GO:0000904 112 0.080
cellular protein complex assembly GO:0043623 178 0.080
response to external stimulus GO:0009605 289 0.079
cellular component assembly GO:0022607 293 0.078
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.078
cell projection morphogenesis GO:0048858 148 0.077
establishment of organelle localization GO:0051656 123 0.076
heterocycle catabolic process GO:0046700 119 0.075
single organism catabolic process GO:0044712 129 0.073
nucleoside phosphate metabolic process GO:0006753 108 0.073
organic substance catabolic process GO:1901575 294 0.073
developmental growth GO:0048589 412 0.072
determination of adult lifespan GO:0008340 812 0.072
multi multicellular organism process GO:0044706 390 0.071
glycosyl compound catabolic process GO:1901658 79 0.071
regulation of biological quality GO:0065008 741 0.068
Mouse
macromolecule localization GO:0033036 771 0.068
Fly
maintenance of location GO:0051235 580 0.068
lipid storage GO:0019915 565 0.066
cellular biosynthetic process GO:0044249 315 0.066
Mouse
cell division GO:0051301 262 0.066
rna metabolic process GO:0016070 228 0.065
organelle assembly GO:0070925 214 0.065
multicellular organismal aging GO:0010259 812 0.065
actin filament based process GO:0030029 191 0.064
endocytosis GO:0006897 819 0.064
pronuclear migration GO:0035046 51 0.064
nucleobase containing compound biosynthetic process GO:0034654 184 0.064
cellular response to stress GO:0033554 162 0.063
establishment of localization in cell GO:0051649 318 0.061
Fly
reproductive behavior GO:0019098 387 0.060
organic cyclic compound catabolic process GO:1901361 119 0.060
regulation of nitrogen compound metabolic process GO:0051171 222 0.059
negative regulation of developmental process GO:0051093 227 0.059
striated muscle cell development GO:0055002 157 0.058
organophosphate catabolic process GO:0046434 81 0.058
multi organism behavior GO:0051705 389 0.057
cell surface receptor signaling pathway GO:0007166 149 0.056
Fly
oocyte development GO:0048599 44 0.056
lipid localization GO:0010876 573 0.056
purine nucleoside catabolic process GO:0006152 75 0.055
regulation of macromolecule biosynthetic process GO:0010556 189 0.054
actomyosin structure organization GO:0031032 154 0.054
response to chemical GO:0042221 356 0.054
regulation of signal transduction GO:0009966 135 0.052
organelle localization GO:0051640 127 0.052
protein catabolic process GO:0030163 162 0.051
regulation of metabolic process GO:0019222 478 0.051
nucleoside phosphate catabolic process GO:1901292 77 0.050
transcription dna templated GO:0006351 168 0.050
muscle cell differentiation GO:0042692 171 0.050
nucleotide metabolic process GO:0009117 108 0.049
oocyte axis specification GO:0007309 2 0.049
anatomical structure formation involved in morphogenesis GO:0048646 250 0.048
negative regulation of gene expression GO:0010629 217 0.048
embryonic morphogenesis GO:0048598 152 0.048
nucleoside triphosphate catabolic process GO:0009143 72 0.048
nucleoside catabolic process GO:0009164 78 0.048
ribonucleoside catabolic process GO:0042454 77 0.048
regulation of cell communication GO:0010646 176 0.047
cellular component assembly involved in morphogenesis GO:0010927 183 0.047
mrna splicing via spliceosome GO:0000398 8 0.047
regulation of meiosis GO:0040020 94 0.047
neurogenesis GO:0022008 236 0.047
purine ribonucleoside catabolic process GO:0046130 75 0.047
establishment of localization GO:0051234 1171 0.046
Fly
regulation of developmental growth GO:0048638 389 0.046
negative regulation of multicellular organismal process GO:0051241 236 0.046
cellular component biogenesis GO:0044085 297 0.046
positive regulation of cellular metabolic process GO:0031325 178 0.046
regulation of cellular biosynthetic process GO:0031326 189 0.045
Mouse
dna metabolic process GO:0006259 74 0.045
regulation of developmental process GO:0050793 684 0.045
cell projection organization GO:0030030 231 0.044
rna localization GO:0006403 3 0.043
positive regulation of developmental growth GO:0048639 354 0.042
aromatic compound catabolic process GO:0019439 116 0.042
purine ribonucleoside metabolic process GO:0046128 92 0.042
muscle cell development GO:0055001 158 0.041
positive regulation of hydrolase activity GO:0051345 38 0.041
nucleoside metabolic process GO:0009116 99 0.040
protein localization GO:0008104 205 0.040
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.040
axonogenesis GO:0007409 102 0.039
cell cycle process GO:0022402 482 0.039
posttranscriptional regulation of gene expression GO:0010608 166 0.039
epithelium development GO:0060429 68 0.039
phosphate containing compound metabolic process GO:0006796 232 0.039
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.039
regulation of molecular function GO:0065009 89 0.038
Mouse
protein complex assembly GO:0006461 186 0.038
negative regulation of gene expression epigenetic GO:0045814 2 0.038
purine ribonucleotide metabolic process GO:0009150 95 0.037
ribonucleotide catabolic process GO:0009261 75 0.037
muscle structure development GO:0061061 191 0.037
cellular component movement GO:0006928 388 0.037
purine containing compound catabolic process GO:0072523 75 0.037
negative regulation of cellular process GO:0048523 239 0.036
Mouse
purine containing compound metabolic process GO:0072521 95 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.035
ribonucleoside metabolic process GO:0009119 98 0.035
macromolecular complex subunit organization GO:0043933 320 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.035
cell morphogenesis GO:0000902 163 0.035
chromosome organization GO:0051276 104 0.035
regulation of gene expression GO:0010468 366 0.035
regulation of post embryonic development GO:0048580 260 0.034
neuron projection guidance GO:0097485 82 0.034
purine nucleoside metabolic process GO:0042278 92 0.034
mitotic spindle organization GO:0007052 81 0.034
cellular nitrogen compound biosynthetic process GO:0044271 192 0.034
behavior GO:0007610 527 0.034
positive regulation of growth GO:0045927 369 0.033
striated muscle cell differentiation GO:0051146 158 0.033
glycosyl compound metabolic process GO:1901657 100 0.033
regulation of response to stimulus GO:0048583 243 0.033
protein modification process GO:0036211 207 0.033
Human
dna duplex unwinding GO:0032508 3 0.032
cellular nitrogen compound catabolic process GO:0044270 119 0.032
neuron differentiation GO:0030182 217 0.031
organophosphate metabolic process GO:0019637 125 0.031
Mouse
organelle fission GO:0048285 363 0.031
digestive tract development GO:0048565 122 0.030
establishment of nucleus localization GO:0040023 55 0.030
cellular response to inorganic substance GO:0071241 3 0.030
regulation of multicellular organism growth GO:0040014 373 0.029
regulation of localization GO:0032879 194 0.029
male anatomical structure morphogenesis GO:0090598 78 0.029
regulation of nuclear division GO:0051783 115 0.029
chromosome segregation GO:0007059 180 0.029
positive regulation of cellular process GO:0048522 332 0.029
nucleobase containing small molecule metabolic process GO:0055086 115 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.027
negative regulation of cellular protein metabolic process GO:0032269 27 0.027
nucleobase containing compound catabolic process GO:0034655 114 0.027
regulation of organelle organization GO:0033043 164 0.026
chromosome organization involved in meiosis GO:0070192 25 0.026
regulation of intracellular signal transduction GO:1902531 77 0.026
nucleic acid templated transcription GO:0097659 169 0.026
regulation of locomotion GO:0040012 161 0.026
tube development GO:0035295 126 0.026
secretion by cell GO:0032940 138 0.026
tube morphogenesis GO:0035239 79 0.026
cellular macromolecular complex assembly GO:0034622 184 0.026
meiotic cell cycle process GO:1903046 170 0.025
negative regulation of nematode larval development GO:0061064 208 0.025
skeletal muscle organ development GO:0060538 3 0.025
response to organic substance GO:0010033 131 0.025
meiosis i GO:0007127 19 0.025
regulation of rna biosynthetic process GO:2001141 165 0.024
positive regulation of multicellular organismal process GO:0051240 417 0.024
positive regulation of cell cycle GO:0045787 55 0.024
germ line stem cell division GO:0042078 9 0.024
purine nucleotide catabolic process GO:0006195 75 0.024
organic substance transport GO:0071702 113 0.024
Fly
ribonucleotide metabolic process GO:0009259 99 0.024
female meiotic division GO:0007143 17 0.024
localization of cell GO:0051674 313 0.024
ribonucleoside triphosphate metabolic process GO:0009199 87 0.024
apical junction assembly GO:0043297 1 0.024
attachment of spindle microtubules to kinetochore GO:0008608 8 0.023
single organism membrane organization GO:0044802 35 0.023
regulation of cell cycle GO:0051726 194 0.023
neuron projection morphogenesis GO:0048812 114 0.023
oxoacid metabolic process GO:0043436 47 0.023
purine nucleotide metabolic process GO:0006163 95 0.023
negative regulation of biological process GO:0048519 567 0.023
asymmetric protein localization GO:0008105 35 0.023
gastrulation GO:0007369 58 0.023
multicellular organism growth GO:0035264 385 0.022
axon development GO:0061564 163 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.022
regulation of cell cycle process GO:0010564 145 0.022
mitotic sister chromatid segregation GO:0000070 38 0.021
nucleus localization GO:0051647 55 0.021
cuticle development GO:0042335 100 0.021
cell part morphogenesis GO:0032990 152 0.021
sister chromatid segregation GO:0000819 46 0.021
dna repair GO:0006281 23 0.021
neuron development GO:0048666 199 0.021
regulation of signaling GO:0023051 172 0.020
histone modification GO:0016570 30 0.020
organic acid metabolic process GO:0006082 47 0.020
nucleoside triphosphate metabolic process GO:0009141 87 0.020
secretion GO:0046903 147 0.020
cellular macromolecule catabolic process GO:0044265 73 0.020
ribose phosphate metabolic process GO:0019693 99 0.020
rna biosynthetic process GO:0032774 169 0.020
cytoplasmic transport GO:0016482 23 0.020
Fly
carbohydrate derivative metabolic process GO:1901135 141 0.019
Mouse
positive regulation of gene expression GO:0010628 112 0.019
ribonucleoside monophosphate metabolic process GO:0009161 45 0.019
epithelial tube morphogenesis GO:0060562 1 0.019
intracellular signal transduction GO:0035556 96 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.018
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.018
digestive system development GO:0055123 122 0.018
regulation of growth GO:0040008 409 0.018
mitotic nuclear division GO:0007067 89 0.018
regulation of multicellular organismal development GO:2000026 317 0.018
negative regulation of translation GO:0017148 10 0.017
negative regulation of response to stimulus GO:0048585 73 0.017
negative regulation of post embryonic development GO:0048581 208 0.017
positive regulation of metabolic process GO:0009893 187 0.017
inductive cell migration GO:0040039 145 0.017
carboxylic acid metabolic process GO:0019752 34 0.017
positive regulation of meiotic cell cycle GO:0051446 47 0.017
axon guidance GO:0007411 82 0.016
myosin filament organization GO:0031033 138 0.016
negative regulation of mitotic cell cycle GO:0045930 42 0.016
male gamete generation GO:0048232 41 0.016
regulation of mitotic cell cycle GO:0007346 76 0.016
negative regulation of cellular metabolic process GO:0031324 95 0.016
Mouse
positive regulation of neurogenesis GO:0050769 4 0.016
regulation of cellular component organization GO:0051128 248 0.016
dna topological change GO:0006265 1 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 8 0.016
nucleoside monophosphate metabolic process GO:0009123 46 0.016
regulation of catabolic process GO:0009894 57 0.016
carbohydrate derivative catabolic process GO:1901136 82 0.016
pole plasm assembly GO:0007315 2 0.015
dna geometric change GO:0032392 3 0.015
negative regulation of metabolic process GO:0009892 240 0.015
cellular response to metal ion GO:0071248 3 0.015
gene silencing GO:0016458 143 0.015
single organism biosynthetic process GO:0044711 91 0.015
Mouse
positive regulation of cell projection organization GO:0031346 4 0.015
defense response GO:0006952 296 0.015
nervous system development GO:0007399 253 0.015
regulation of purine nucleotide catabolic process GO:0033121 35 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.015
transcription from rna polymerase ii promoter GO:0006366 149 0.015
ribonucleoprotein complex assembly GO:0022618 4 0.015
membrane organization GO:0061024 135 0.015
male sex differentiation GO:0046661 86 0.015
myosin filament assembly GO:0031034 138 0.015
negative regulation of cellular component organization GO:0051129 33 0.015
chemotaxis GO:0006935 120 0.014
protein localization to organelle GO:0033365 37 0.014
Fly
negative regulation of signaling GO:0023057 61 0.014
phosphorus metabolic process GO:0006793 232 0.014
Mouse
regulation of cell proliferation GO:0042127 105 0.014
spermatogenesis GO:0007283 41 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.014
regulation of primary metabolic process GO:0080090 292 0.013
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 72 0.013
positive regulation of biosynthetic process GO:0009891 109 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
regulation of hydrolase activity GO:0051336 45 0.013
head development GO:0060322 1 0.013
nematode male tail tip morphogenesis GO:0045138 77 0.013
dendrite development GO:0016358 42 0.013
response to metal ion GO:0010038 33 0.013
cellular response to hormone stimulus GO:0032870 14 0.013
bmp signaling pathway GO:0030509 3 0.013
nuclear migration GO:0007097 54 0.013
positive regulation of chromosome organization GO:2001252 2 0.013
taxis GO:0042330 128 0.013
signaling GO:0023052 401 0.013
Fly
establishment of protein localization GO:0045184 50 0.012
Fly
regulation of protein stability GO:0031647 3 0.012
atp catabolic process GO:0006200 27 0.012
digestive tract morphogenesis GO:0048546 76 0.012
regulation of cell motility GO:2000145 57 0.012
negative regulation of macromolecule metabolic process GO:0010605 229 0.012
regulation of programmed cell death GO:0043067 50 0.012
regulation of gene expression epigenetic GO:0040029 163 0.012
amine metabolic process GO:0009308 15 0.012
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 35 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
negative regulation of cellular biosynthetic process GO:0031327 65 0.012
response to oxygen containing compound GO:1901700 44 0.012
negative regulation of rna metabolic process GO:0051253 53 0.012
regulation of atp catabolic process GO:1903289 3 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
mrna processing GO:0006397 13 0.011
cellular protein localization GO:0034613 75 0.011
Fly
negative regulation of cell cycle GO:0045786 53 0.011
protein localization to endoplasmic reticulum GO:0070972 2 0.011
cell proliferation GO:0008283 116 0.011
regulation of ras protein signal transduction GO:0046578 41 0.011
regulation of cellular response to oxidative stress GO:1900407 1 0.011
response to inorganic substance GO:0010035 50 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
negative regulation of protein metabolic process GO:0051248 27 0.010
regulation of cellular catabolic process GO:0031329 51 0.010
ribonucleoprotein complex biogenesis GO:0022613 8 0.010
regulation of apoptotic process GO:0042981 36 0.010
membrane invagination GO:0010324 98 0.010
mitotic g2 m transition checkpoint GO:0044818 1 0.010
regulation of cellular protein metabolic process GO:0032268 75 0.010

npp-9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
cardiovascular system disease DOID:1287 0 0.027
nervous system disease DOID:863 0 0.023
myopathy DOID:423 0 0.022
muscular disease DOID:0080000 0 0.022
musculoskeletal system disease DOID:17 0 0.022
muscle tissue disease DOID:66 0 0.022