Caenorhabditis elegans

14 known processes

mec-1 (CELE_T07H8.4)

Protein MEC-1

mec-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.512
embryo development ending in birth or egg hatching GO:0009792 2992 0.507
post embryonic development GO:0009791 2152 0.355
establishment of localization GO:0051234 1171 0.352
multi multicellular organism process GO:0044706 390 0.304
locomotion GO:0040011 1634 0.285
gonad development GO:0008406 840 0.262
organ development GO:0048513 1102 0.257
body morphogenesis GO:0010171 620 0.250
eating behavior GO:0042755 59 0.230
oviposition GO:0018991 364 0.224
multi organism reproductive process GO:0044703 867 0.212
transport GO:0006810 1093 0.202
multicellular organism reproduction GO:0032504 819 0.192
behavior GO:0007610 527 0.187
multicellular organismal reproductive behavior GO:0033057 384 0.169
single organism signaling GO:0044700 401 0.167
vesicle mediated transport GO:0016192 852 0.166
reproductive structure development GO:0048608 850 0.163
response to chemical GO:0042221 356 0.160
multi organism reproductive behavior GO:0044705 387 0.160
genitalia development GO:0048806 741 0.158
multi organism behavior GO:0051705 389 0.157
regulation of multicellular organismal process GO:0051239 726 0.152
endocytosis GO:0006897 819 0.145
single organism localization GO:1902578 518 0.144
regulation of response to stimulus GO:0048583 243 0.140
regulation of metabolic process GO:0019222 478 0.135
positive regulation of developmental growth GO:0048639 354 0.130
single organism reproductive process GO:0044702 1196 0.124
signaling GO:0023052 401 0.122
organelle organization GO:0006996 783 0.121
regulation of reproductive process GO:2000241 66 0.121
reproductive behavior GO:0019098 387 0.120
single organism transport GO:0044765 447 0.119
gamete generation GO:0007276 461 0.116
single organism organelle organization GO:1902589 501 0.112
regulation of developmental growth GO:0048638 389 0.111
determination of adult lifespan GO:0008340 812 0.110
regulation of primary metabolic process GO:0080090 292 0.109
regulation of biological quality GO:0065008 741 0.108
development of primary sexual characteristics GO:0045137 840 0.108
regulation of developmental process GO:0050793 684 0.105
macromolecule localization GO:0033036 771 0.105
receptor mediated endocytosis GO:0006898 715 0.104
positive regulation of developmental process GO:0051094 408 0.104
organic substance catabolic process GO:1901575 294 0.103
sensory organ morphogenesis GO:0090596 2 0.103
sexual reproduction GO:0019953 546 0.103
signal transduction GO:0007165 317 0.101
multicellular organismal reproductive process GO:0048609 815 0.099
regulation of multi organism process GO:0043900 69 0.098
cell migration GO:0016477 306 0.093
sex differentiation GO:0007548 909 0.092
cellular response to chemical stimulus GO:0070887 129 0.092
protein catabolic process GO:0030163 162 0.090
multicellular organism growth GO:0035264 385 0.088
muscle structure development GO:0061061 191 0.087
actin cytoskeleton organization GO:0030036 184 0.087
feeding behavior GO:0007631 70 0.086
growth GO:0040007 562 0.086
cell surface receptor signaling pathway GO:0007166 149 0.085
regulation of gene expression GO:0010468 366 0.084
catabolic process GO:0009056 318 0.083
protein metabolic process GO:0019538 422 0.082
regulation of cation channel activity GO:2001257 3 0.080
response to mechanical stimulus GO:0009612 28 0.080
cellular component movement GO:0006928 388 0.078
cell development GO:0048468 696 0.077
regulation of locomotion GO:0040012 161 0.076
lipid localization GO:0010876 573 0.076
aging GO:0007568 812 0.075
transmembrane transport GO:0055085 110 0.074
regulation of macromolecule metabolic process GO:0060255 421 0.073
negative regulation of biological process GO:0048519 567 0.072
cell motility GO:0048870 313 0.072
maintenance of location GO:0051235 580 0.072
negative regulation of transporter activity GO:0032410 3 0.069
regulation of oocyte maturation GO:1900193 7 0.068
cellular component assembly involved in morphogenesis GO:0010927 183 0.068
cellular protein metabolic process GO:0044267 279 0.067
mechanosensory behavior GO:0007638 25 0.067
phosphate containing compound metabolic process GO:0006796 232 0.065
localization of cell GO:0051674 313 0.063
reproductive system development GO:0061458 850 0.063
lipid storage GO:0019915 565 0.063
nucleic acid metabolic process GO:0090304 299 0.062
phosphorylation GO:0016310 116 0.062
regulation of multicellular organism growth GO:0040014 373 0.061
intracellular receptor signaling pathway GO:0030522 2 0.060
positive regulation of multicellular organismal process GO:0051240 417 0.059
multicellular organismal aging GO:0010259 812 0.059
developmental process involved in reproduction GO:0003006 1165 0.058
programmed cell death GO:0012501 500 0.058
synaptic transmission GO:0007268 106 0.058
positive regulation of multicellular organism growth GO:0040018 352 0.056
striated muscle cell development GO:0055002 157 0.056
organelle assembly GO:0070925 214 0.055
positive regulation of rna biosynthetic process GO:1902680 102 0.054
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.054
regulation of pharyngeal pumping GO:0043051 36 0.053
phosphorus metabolic process GO:0006793 232 0.052
death GO:0016265 547 0.052
regulation of growth GO:0040008 409 0.052
ion transmembrane transport GO:0034220 91 0.051
regulation of behavior GO:0050795 97 0.051
developmental growth GO:0048589 412 0.050
gene expression GO:0010467 412 0.049
hermaphrodite genitalia development GO:0040035 734 0.049
positive regulation of cellular process GO:0048522 332 0.048
cell projection organization GO:0030030 231 0.048
muscle cell differentiation GO:0042692 171 0.048
cell death GO:0008219 547 0.047
embryonic body morphogenesis GO:0010172 49 0.047
protein complex biogenesis GO:0070271 186 0.046
actin filament based process GO:0030029 191 0.046
cellular response to organic substance GO:0071310 119 0.046
myofibril assembly GO:0030239 154 0.045
pharyngeal pumping GO:0043050 58 0.045
striated muscle cell differentiation GO:0051146 158 0.045
cellular protein complex assembly GO:0043623 178 0.045
germ cell development GO:0007281 351 0.044
cellular component assembly GO:0022607 293 0.044
positive regulation of cellular metabolic process GO:0031325 178 0.044
anatomical structure formation involved in morphogenesis GO:0048646 250 0.044
regulation of multicellular organismal development GO:2000026 317 0.044
biosynthetic process GO:0009058 323 0.044
regulation of signal transduction GO:0009966 135 0.044
response to external stimulus GO:0009605 289 0.043
positive regulation of growth GO:0045927 369 0.042
epithelial cell proliferation GO:0050673 1 0.041
taxis GO:0042330 128 0.041
protein complex subunit organization GO:0071822 280 0.041
apoptotic process GO:0006915 478 0.040
regulation of neuromuscular synaptic transmission GO:1900073 1 0.040
regulation of rna metabolic process GO:0051252 173 0.039
response to abiotic stimulus GO:0009628 152 0.038
intercellular transport GO:0010496 1 0.037
negative regulation of multicellular organismal process GO:0051241 236 0.037
membrane organization GO:0061024 135 0.037
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.037
ion transport GO:0006811 113 0.036
regulation of epithelial cell proliferation GO:0050678 1 0.036
muscle cell development GO:0055001 158 0.036
cellular component biogenesis GO:0044085 297 0.035
regulation of feeding behavior GO:0060259 38 0.034
actomyosin structure organization GO:0031032 154 0.034
regulation of synaptic transmission GO:0050804 34 0.033
generation of neurons GO:0048699 235 0.032
positive regulation of metabolic process GO:0009893 187 0.032
molting cycle GO:0042303 281 0.032
macromolecule biosynthetic process GO:0009059 250 0.031
chemotaxis GO:0006935 120 0.031
protein complex assembly GO:0006461 186 0.031
macromolecule catabolic process GO:0009057 202 0.030
cellular component morphogenesis GO:0032989 318 0.030
cellular macromolecular complex assembly GO:0034622 184 0.030
oocyte differentiation GO:0009994 45 0.030
defecation rhythm GO:0035882 3 0.030
regulation of macromolecule biosynthetic process GO:0010556 189 0.029
muscle tissue development GO:0060537 1 0.029
oocyte development GO:0048599 44 0.029
oogenesis GO:0048477 229 0.029
macromolecule modification GO:0043412 218 0.028
phagocytosis engulfment GO:0006911 98 0.028
negative regulation of signal transduction GO:0009968 60 0.028
male mating behavior GO:0060179 26 0.028
protein modification process GO:0036211 207 0.027
cell projection morphogenesis GO:0048858 148 0.027
engulfment of apoptotic cell GO:0043652 94 0.027
cytoskeleton organization GO:0007010 339 0.026
negative regulation of cellular process GO:0048523 239 0.026
membrane invagination GO:0010324 98 0.025
cell division GO:0051301 262 0.025
regulation of response to wounding GO:1903034 1 0.025
nervous system development GO:0007399 253 0.025
cellular macromolecule biosynthetic process GO:0034645 247 0.025
striated muscle myosin thick filament assembly GO:0071688 138 0.025
myosin filament assembly GO:0031034 138 0.025
regulation of cellular metabolic process GO:0031323 305 0.024
protein phosphorylation GO:0006468 85 0.024
negative regulation of gene expression GO:0010629 217 0.024
negative regulation of macromolecule metabolic process GO:0010605 229 0.024
head development GO:0060322 1 0.023
rna biosynthetic process GO:0032774 169 0.023
chemosensory behavior GO:0007635 33 0.022
regulation of nitrogen compound metabolic process GO:0051171 222 0.022
inactivation of mapkkk activity GO:0051390 2 0.022
negative regulation of transmembrane transport GO:0034763 3 0.022
adult behavior GO:0030534 3 0.021
macromolecular complex subunit organization GO:0043933 320 0.021
muscle organ development GO:0007517 26 0.021
protein localization GO:0008104 205 0.021
cellular biosynthetic process GO:0044249 315 0.021
myosin filament organization GO:0031033 138 0.021
mating GO:0007618 34 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.020
cellular protein modification process GO:0006464 207 0.020
tube development GO:0035295 126 0.020
response to bacterium GO:0009617 86 0.020
aromatic compound biosynthetic process GO:0019438 192 0.019
regulation of cellular biosynthetic process GO:0031326 189 0.019
establishment of localization in cell GO:0051649 318 0.019
positive regulation of cellular biosynthetic process GO:0031328 109 0.019
negative regulation of response to stimulus GO:0048585 73 0.019
inductive cell migration GO:0040039 145 0.019
muscle organ morphogenesis GO:0048644 4 0.019
female gamete generation GO:0007292 254 0.019
organic substance biosynthetic process GO:1901576 323 0.018
negative regulation of cation channel activity GO:2001258 2 0.018
regulation of post embryonic development GO:0048580 260 0.018
macromolecular complex assembly GO:0065003 193 0.018
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.018
apoptotic cell clearance GO:0043277 111 0.018
negative regulation of cell communication GO:0010648 61 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 6 0.017
regulation of protein metabolic process GO:0051246 81 0.017
excretion GO:0007588 49 0.017
neuron differentiation GO:0030182 217 0.017
peptidyl tyrosine phosphorylation GO:0018108 2 0.017
cell recognition GO:0008037 85 0.016
regulation of molecular function GO:0065009 89 0.016
regulation of cell proliferation GO:0042127 105 0.016
nucleobase containing compound metabolic process GO:0006139 406 0.016
negative regulation of signaling GO:0023057 61 0.016
phagocytosis GO:0006909 115 0.015
regulation of nucleic acid templated transcription GO:1903506 165 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
transcription from rna polymerase ii promoter GO:0006366 149 0.015
response to anesthetic GO:0072347 1 0.015
negative regulation of developmental process GO:0051093 227 0.015
regulation of ion transport GO:0043269 39 0.015
organ morphogenesis GO:0009887 67 0.015
cellular localization GO:0051641 360 0.015
positive regulation of biosynthetic process GO:0009891 109 0.015
neurogenesis GO:0022008 236 0.015
ovulation GO:0030728 33 0.014
cuticle development GO:0042335 100 0.014
cell cell signaling GO:0007267 118 0.014
cell type specific apoptotic process GO:0097285 4 0.014
tissue development GO:0009888 112 0.014
epithelial tube morphogenesis GO:0060562 1 0.014
regulation of cellular protein metabolic process GO:0032268 75 0.014
neuron projection development GO:0031175 187 0.014
defense response to other organism GO:0098542 100 0.013
embryonic morphogenesis GO:0048598 152 0.013
cell substrate adhesion GO:0031589 1 0.013
regulation of oviposition GO:0046662 43 0.013
regulation of phosphorus metabolic process GO:0051174 81 0.013
rna interference GO:0016246 137 0.013
axon development GO:0061564 163 0.013
nucleic acid templated transcription GO:0097659 169 0.013
protein oligomerization GO:0051259 4 0.013
neuron recognition GO:0008038 83 0.012
negative regulation of metabolic process GO:0009892 240 0.012
adult locomotory behavior GO:0008344 1 0.012
regulation of rna biosynthetic process GO:2001141 165 0.012
signal transduction by phosphorylation GO:0023014 31 0.012
locomotory behavior GO:0007626 40 0.012
regulation of system process GO:0044057 27 0.012
pattern specification process GO:0007389 59 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
transcription dna templated GO:0006351 168 0.012
system process GO:0003008 136 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.012
regulation of transport GO:0051049 91 0.012
regulation of nematode larval development GO:0061062 260 0.012
regulation of catalytic activity GO:0050790 78 0.012
protein localization to membrane GO:0072657 11 0.012
secretion GO:0046903 147 0.012
regulation of cell communication GO:0010646 176 0.012
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 5 0.011
regulation of phosphate metabolic process GO:0019220 81 0.011
cell maturation GO:0048469 26 0.011
purine nucleoside metabolic process GO:0042278 92 0.011
negative regulation of ion transport GO:0043271 7 0.011
regulation of defecation rhythm GO:2000746 3 0.011
cellular ketone metabolic process GO:0042180 14 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 13 0.011
axonal fasciculation GO:0007413 79 0.011
digestive tract development GO:0048565 122 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
posttranscriptional gene silencing GO:0016441 143 0.011
small molecule metabolic process GO:0044281 186 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.011
defense response to bacterium GO:0042742 86 0.011
response to wounding GO:0009611 4 0.011
establishment of protein localization GO:0045184 50 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.010
cell cycle process GO:0022402 482 0.010
organic cyclic compound biosynthetic process GO:1901362 195 0.010
intracellular signal transduction GO:0035556 96 0.010
rna metabolic process GO:0016070 228 0.010
regulation of cell differentiation GO:0045595 81 0.010
positive regulation of gene expression GO:0010628 112 0.010
response to other organism GO:0051707 101 0.010
neuron development GO:0048666 199 0.010
negative regulation of cellular metabolic process GO:0031324 95 0.010
cation transmembrane transport GO:0098655 59 0.010
neurological system process GO:0050877 53 0.010

mec-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.011