Caenorhabditis elegans

51 known processes

unc-98 (CELE_F08C6.7)

Protein UNC-98

unc-98 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component movement GO:0006928 388 0.879
cell migration GO:0016477 306 0.762
embryo development GO:0009790 3052 0.713
cellular component morphogenesis GO:0032989 318 0.567
single organism reproductive process GO:0044702 1196 0.559
post embryonic development GO:0009791 2152 0.536
transcription dna templated GO:0006351 168 0.503
digestive tract morphogenesis GO:0048546 76 0.494
cell motility GO:0048870 313 0.481
single organism organelle organization GO:1902589 501 0.451
localization of cell GO:0051674 313 0.437
cell projection organization GO:0030030 231 0.427
muscle cell differentiation GO:0042692 171 0.418
axonogenesis GO:0007409 102 0.413
post embryonic organ development GO:0048569 336 0.401
tube development GO:0035295 126 0.390
chemotaxis GO:0006935 120 0.390
organelle organization GO:0006996 783 0.377
cell part morphogenesis GO:0032990 152 0.374
cell projection morphogenesis GO:0048858 148 0.374
anatomical structure formation involved in morphogenesis GO:0048646 250 0.371
biosynthetic process GO:0009058 323 0.359
response to chemical GO:0042221 356 0.357
negative regulation of cellular process GO:0048523 239 0.355
digestive system development GO:0055123 122 0.345
reproductive system development GO:0061458 850 0.343
tube morphogenesis GO:0035239 79 0.316
regulation of developmental process GO:0050793 684 0.312
gastrulation GO:0007369 58 0.308
axon guidance GO:0007411 82 0.305
digestive tract development GO:0048565 122 0.295
axon development GO:0061564 163 0.294
neuron projection guidance GO:0097485 82 0.278
neurogenesis GO:0022008 236 0.277
positive regulation of developmental process GO:0051094 408 0.277
generation of neurons GO:0048699 235 0.274
locomotion GO:0040011 1634 0.264
establishment of localization GO:0051234 1171 0.255
myofibril assembly GO:0030239 154 0.253
organ development GO:0048513 1102 0.249
nucleic acid metabolic process GO:0090304 299 0.243
taxis GO:0042330 128 0.240
embryonic morphogenesis GO:0048598 152 0.240
regulation of locomotion GO:0040012 161 0.237
skeletal muscle organ development GO:0060538 3 0.236
regulation of cell motility GO:2000145 57 0.230
regulation of cell migration GO:0030334 55 0.225
multi organism reproductive process GO:0044703 867 0.223
regulation of cell differentiation GO:0045595 81 0.223
transport GO:0006810 1093 0.222
sex differentiation GO:0007548 909 0.221
cellular component biogenesis GO:0044085 297 0.220
organ morphogenesis GO:0009887 67 0.218
negative regulation of biological process GO:0048519 567 0.215
cell development GO:0048468 696 0.215
neuron projection development GO:0031175 187 0.212
positive regulation of gene expression GO:0010628 112 0.209
epithelium development GO:0060429 68 0.201
developmental process involved in reproduction GO:0003006 1165 0.199
regulation of cellular metabolic process GO:0031323 305 0.197
embryo development ending in birth or egg hatching GO:0009792 2992 0.192
regulation of multicellular organismal development GO:2000026 317 0.190
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.190
cell fate commitment GO:0045165 139 0.185
gamete generation GO:0007276 461 0.182
growth GO:0040007 562 0.181
development of primary sexual characteristics GO:0045137 840 0.176
reproductive structure development GO:0048608 850 0.176
positive regulation of rna biosynthetic process GO:1902680 102 0.173
cell cycle GO:0007049 526 0.172
female gamete generation GO:0007292 254 0.169
protein catabolic process GO:0030163 162 0.169
vulval development GO:0040025 333 0.165
response to external stimulus GO:0009605 289 0.161
muscle structure development GO:0061061 191 0.161
cell morphogenesis GO:0000902 163 0.161
positive regulation of transcription dna templated GO:0045893 102 0.159
multicellular organism reproduction GO:0032504 819 0.159
positive regulation of rna metabolic process GO:0051254 103 0.158
sexual reproduction GO:0019953 546 0.155
gene expression GO:0010467 412 0.150
regulation of cellular component movement GO:0051270 62 0.150
regulation of response to stimulus GO:0048583 243 0.148
cytoskeleton organization GO:0007010 339 0.147
protein metabolic process GO:0019538 422 0.145
endocytosis GO:0006897 819 0.142
nervous system development GO:0007399 253 0.141
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.137
neuron recognition GO:0008038 83 0.137
regulation of nitrogen compound metabolic process GO:0051171 222 0.137
nucleic acid templated transcription GO:0097659 169 0.136
striated muscle cell development GO:0055002 157 0.136
macromolecule catabolic process GO:0009057 202 0.135
regulation of nematode larval development GO:0061062 260 0.135
regulation of multicellular organismal process GO:0051239 726 0.134
pattern specification process GO:0007389 59 0.134
regulation of vulval development GO:0040028 248 0.134
positive regulation of cellular process GO:0048522 332 0.131
regulation of macromolecule metabolic process GO:0060255 421 0.131
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.130
macromolecule biosynthetic process GO:0009059 250 0.130
cellular biosynthetic process GO:0044249 315 0.126
cellular component assembly GO:0022607 293 0.121
neuron projection morphogenesis GO:0048812 114 0.121
regulation of nucleic acid templated transcription GO:1903506 165 0.118
regulation of signal transduction GO:0009966 135 0.117
signal transduction GO:0007165 317 0.116
regulation of cell communication GO:0010646 176 0.116
regulation of signaling GO:0023051 172 0.115
positive regulation of nucleic acid templated transcription GO:1903508 102 0.115
negative regulation of metabolic process GO:0009892 240 0.113
cell morphogenesis involved in differentiation GO:0000904 112 0.111
cellular nitrogen compound biosynthetic process GO:0044271 192 0.109
negative regulation of multicellular organismal process GO:0051241 236 0.108
signaling GO:0023052 401 0.108
mesoderm development GO:0007498 27 0.107
muscle tissue development GO:0060537 1 0.107
positive regulation of biosynthetic process GO:0009891 109 0.106
regulation of biological quality GO:0065008 741 0.106
defense response GO:0006952 296 0.105
tissue morphogenesis GO:0048729 65 0.103
muscle organ development GO:0007517 26 0.102
regulation of biosynthetic process GO:0009889 189 0.101
regulation of metabolic process GO:0019222 478 0.101
actomyosin structure organization GO:0031032 154 0.100
negative regulation of developmental process GO:0051093 227 0.098
regulation of post embryonic development GO:0048580 260 0.096
single organism signaling GO:0044700 401 0.094
multicellular organismal reproductive process GO:0048609 815 0.093
positive regulation of metabolic process GO:0009893 187 0.093
single organism localization GO:1902578 518 0.093
regulation of growth GO:0040008 409 0.092
system process GO:0003008 136 0.092
developmental growth GO:0048589 412 0.091
body morphogenesis GO:0010171 620 0.090
muscle organ morphogenesis GO:0048644 4 0.087
hermaphrodite genitalia development GO:0040035 734 0.086
nucleobase containing compound metabolic process GO:0006139 406 0.086
regulation of gene expression GO:0010468 366 0.086
gonad development GO:0008406 840 0.083
multicellular organismal aging GO:0010259 812 0.082
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.081
organelle assembly GO:0070925 214 0.080
transcription from rna polymerase ii promoter GO:0006366 149 0.078
muscle cell development GO:0055001 158 0.077
macromolecule localization GO:0033036 771 0.076
cellular component assembly involved in morphogenesis GO:0010927 183 0.076
cell death GO:0008219 547 0.075
maintenance of location GO:0051235 580 0.075
head development GO:0060322 1 0.075
regulation of primary metabolic process GO:0080090 292 0.074
regulation of developmental growth GO:0048638 389 0.073
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.073
germ cell development GO:0007281 351 0.073
genitalia development GO:0048806 741 0.073
cellular localization GO:0051641 360 0.073
macromolecular complex subunit organization GO:0043933 320 0.072
tissue development GO:0009888 112 0.072
regulation of multicellular organism growth GO:0040014 373 0.071
death GO:0016265 547 0.070
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.070
aromatic compound biosynthetic process GO:0019438 192 0.069
multicellular organismal reproductive behavior GO:0033057 384 0.069
neuron differentiation GO:0030182 217 0.068
regionalization GO:0003002 31 0.067
receptor mediated endocytosis GO:0006898 715 0.067
actin cytoskeleton organization GO:0030036 184 0.065
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.065
organic substance catabolic process GO:1901575 294 0.063
regulation of cellular component organization GO:0051128 248 0.063
organonitrogen compound metabolic process GO:1901564 151 0.062
positive regulation of cellular metabolic process GO:0031325 178 0.062
negative regulation of macromolecule metabolic process GO:0010605 229 0.062
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.061
lipid localization GO:0010876 573 0.060
regulation of transport GO:0051049 91 0.059
epithelial tube morphogenesis GO:0060562 1 0.057
regulation of localization GO:0032879 194 0.057
lipid storage GO:0019915 565 0.057
regulation of cellular biosynthetic process GO:0031326 189 0.057
macromolecule modification GO:0043412 218 0.056
organic substance biosynthetic process GO:1901576 323 0.056
regulation of transcription dna templated GO:0006355 164 0.055
positive regulation of multicellular organism growth GO:0040018 352 0.054
oxoacid metabolic process GO:0043436 47 0.054
cellular macromolecule biosynthetic process GO:0034645 247 0.054
protein complex biogenesis GO:0070271 186 0.052
positive regulation of multicellular organismal process GO:0051240 417 0.052
single organism catabolic process GO:0044712 129 0.052
regulation of cell development GO:0060284 49 0.052
rna biosynthetic process GO:0032774 169 0.052
catabolic process GO:0009056 318 0.051
striated muscle cell differentiation GO:0051146 158 0.051
response to wounding GO:0009611 4 0.051
negative regulation of gene expression GO:0010629 217 0.050
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.050
negative regulation of nematode larval development GO:0061064 208 0.050
rna localization GO:0006403 3 0.050
nucleobase containing compound biosynthetic process GO:0034654 184 0.049
vesicle mediated transport GO:0016192 852 0.049
programmed cell death GO:0012501 500 0.048
positive regulation of growth GO:0045927 369 0.048
negative regulation of nucleic acid templated transcription GO:1903507 53 0.048
organelle fission GO:0048285 363 0.046
positive regulation of developmental growth GO:0048639 354 0.046
positive regulation of cellular biosynthetic process GO:0031328 109 0.045
endodermal cell differentiation GO:0035987 18 0.045
regulation of neuron differentiation GO:0045664 40 0.044
multicellular organism growth GO:0035264 385 0.044
epithelial cell proliferation GO:0050673 1 0.044
striated muscle myosin thick filament assembly GO:0071688 138 0.043
regulation of rna biosynthetic process GO:2001141 165 0.043
heterocycle biosynthetic process GO:0018130 187 0.043
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.042
multi organism behavior GO:0051705 389 0.042
protein localization GO:0008104 205 0.042
negative regulation of cellular metabolic process GO:0031324 95 0.042
actin filament based process GO:0030029 191 0.041
immune response GO:0006955 192 0.040
male gamete generation GO:0048232 41 0.040
cell projection assembly GO:0030031 35 0.039
membrane organization GO:0061024 135 0.039
regulation of neurogenesis GO:0050767 40 0.039
regulation of rna metabolic process GO:0051252 173 0.039
regulation of organ morphogenesis GO:2000027 4 0.039
positive regulation of macromolecule metabolic process GO:0010604 149 0.038
cellular protein complex assembly GO:0043623 178 0.038
cellular macromolecular complex assembly GO:0034622 184 0.038
axonal fasciculation GO:0007413 79 0.038
inductive cell migration GO:0040039 145 0.037
determination of adult lifespan GO:0008340 812 0.037
rna metabolic process GO:0016070 228 0.036
cellular protein metabolic process GO:0044267 279 0.035
cell recognition GO:0008037 85 0.034
sensory organ morphogenesis GO:0090596 2 0.034
single organism transport GO:0044765 447 0.034
cell proliferation GO:0008283 116 0.034
aging GO:0007568 812 0.033
neuron development GO:0048666 199 0.032
cell matrix adhesion GO:0007160 1 0.032
collagen and cuticulin based cuticle development GO:0040002 99 0.032
cellular protein modification process GO:0006464 207 0.031
regulation of cell cycle GO:0051726 194 0.030
meiotic cell cycle GO:0051321 335 0.030
anterior posterior axis specification GO:0009948 17 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.030
meiotic nuclear division GO:0007126 300 0.030
small molecule metabolic process GO:0044281 186 0.030
oogenesis GO:0048477 229 0.030
phagocytosis engulfment GO:0006911 98 0.030
reproductive behavior GO:0019098 387 0.029
oviposition GO:0018991 364 0.029
response to other organism GO:0051707 101 0.028
macromolecular complex assembly GO:0065003 193 0.028
organic substance transport GO:0071702 113 0.028
defense response to fungus GO:0050832 19 0.028
regulation of macromolecule biosynthetic process GO:0010556 189 0.028
phagocytosis GO:0006909 115 0.028
negative regulation of neurogenesis GO:0050768 4 0.027
myosin filament assembly GO:0031034 138 0.027
negative regulation of post embryonic development GO:0048581 208 0.026
muscle attachment GO:0016203 3 0.026
regulation of cell proliferation GO:0042127 105 0.026
response to fungus GO:0009620 20 0.025
negative regulation of transcription dna templated GO:0045892 53 0.025
response to abiotic stimulus GO:0009628 152 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.025
myosin filament organization GO:0031033 138 0.025
cell division GO:0051301 262 0.024
anterior posterior pattern specification GO:0009952 27 0.024
neurological system process GO:0050877 53 0.024
negative regulation of cell communication GO:0010648 61 0.024
single organism behavior GO:0044708 83 0.024
regulation of organelle organization GO:0033043 164 0.023
multi organism reproductive behavior GO:0044705 387 0.023
regulation of nervous system development GO:0051960 41 0.023
endoderm development GO:0007492 20 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.022
regulation of cell morphogenesis GO:0022604 40 0.022
embryonic body morphogenesis GO:0010172 49 0.022
organic acid metabolic process GO:0006082 47 0.022
cell surface receptor signaling pathway GO:0007166 149 0.022
innate immune response GO:0045087 190 0.021
negative regulation of cellular biosynthetic process GO:0031327 65 0.021
regulation of epithelial cell proliferation GO:0050678 1 0.021
negative regulation of signal transduction GO:0009968 60 0.020
maintenance of protein location GO:0045185 15 0.020
regulation of cytoplasmic transport GO:1903649 3 0.020
axis specification GO:0009798 23 0.020
positive regulation of cell communication GO:0010647 69 0.020
defense response to other organism GO:0098542 100 0.020
epithelial cell differentiation GO:0030855 17 0.020
cilium morphogenesis GO:0060271 33 0.019
cell substrate adhesion GO:0031589 1 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.019
regulation of apoptotic signaling pathway GO:2001233 1 0.019
response to nutrient levels GO:0031667 35 0.019
negative adaptation of signaling pathway GO:0022401 3 0.019
developmental cell growth GO:0048588 39 0.018
response to external biotic stimulus GO:0043207 101 0.018
carboxylic acid metabolic process GO:0019752 34 0.018
regulation of cellular localization GO:0060341 42 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.018
apoptotic cell clearance GO:0043277 111 0.018
cellular response to stress GO:0033554 162 0.017
molting cycle GO:0042303 281 0.017
positive regulation of cell projection organization GO:0031346 4 0.017
cuticle development GO:0042335 100 0.017
multi multicellular organism process GO:0044706 390 0.017
protein modification process GO:0036211 207 0.017
negative regulation of signaling GO:0023057 61 0.017
regulation of phosphate metabolic process GO:0019220 81 0.016
protein complex subunit organization GO:0071822 280 0.016
positive regulation of phosphorus metabolic process GO:0010562 56 0.016
protein complex assembly GO:0006461 186 0.016
ion transport GO:0006811 113 0.016
biological adhesion GO:0022610 21 0.016
regulation of anatomical structure morphogenesis GO:0022603 51 0.016
cellular response to organic substance GO:0071310 119 0.016
positive regulation of neuron differentiation GO:0045666 4 0.016
behavior GO:0007610 527 0.016
phosphate containing compound metabolic process GO:0006796 232 0.015
negative regulation of response to stimulus GO:0048585 73 0.015
positive regulation of response to stimulus GO:0048584 55 0.015
oocyte construction GO:0007308 2 0.015
response to biotic stimulus GO:0009607 101 0.015
positive regulation of cell migration GO:0030335 3 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
regulation of phosphorus metabolic process GO:0051174 81 0.015
regulation of programmed cell death GO:0043067 50 0.014
mitotic cell cycle process GO:1903047 194 0.014
negative regulation of biosynthetic process GO:0009890 65 0.014
amine metabolic process GO:0009308 15 0.014
homeostatic process GO:0042592 51 0.014
intracellular signal transduction GO:0035556 96 0.014
spermatogenesis GO:0007283 41 0.014
cellular amine metabolic process GO:0044106 15 0.014
stem cell differentiation GO:0048863 7 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.013
single organism intracellular transport GO:1902582 70 0.013
membrane invagination GO:0010324 98 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
phosphorus metabolic process GO:0006793 232 0.013
pharynx development GO:0060465 51 0.013
apoptotic process GO:0006915 478 0.013
positive regulation of embryonic development GO:0040019 3 0.013
regulation of cell death GO:0010941 65 0.013
organic cyclic compound biosynthetic process GO:1901362 195 0.012
metal ion transport GO:0030001 49 0.012
striated muscle contraction involved in embryonic body morphogenesis GO:0061199 13 0.012
regulation of phosphorylation GO:0042325 45 0.012
learning or memory GO:0007611 27 0.012
ion transmembrane transport GO:0034220 91 0.012
negative regulation of cellular component organization GO:0051129 33 0.012
microtubule based process GO:0007017 182 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
mitochondrion organization GO:0007005 20 0.011
establishment of localization in cell GO:0051649 318 0.011
posttranscriptional gene silencing by rna GO:0035194 143 0.011
negative regulation of rna biosynthetic process GO:1902679 53 0.011
positive regulation of vulval development GO:0040026 52 0.011
positive regulation of neurogenesis GO:0050769 4 0.011
rna interference GO:0016246 137 0.011
cell maturation GO:0048469 26 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
regulation of catalytic activity GO:0050790 78 0.011
regulation of bmp signaling pathway GO:0030510 3 0.011
developmental growth involved in morphogenesis GO:0060560 37 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
cellular protein localization GO:0034613 75 0.011
response to acid chemical GO:0001101 4 0.011
negative regulation of vulval development GO:0040027 206 0.011
small molecule biosynthetic process GO:0044283 38 0.011
protein oligomerization GO:0051259 4 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
positive regulation of protein transport GO:0051222 4 0.010
carbohydrate derivative metabolic process GO:1901135 141 0.010
cell adhesion GO:0007155 21 0.010
engulfment of apoptotic cell GO:0043652 94 0.010

unc-98 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.056
muscular disease DOID:0080000 0 0.056
heart disease DOID:114 0 0.056
cardiomyopathy DOID:0050700 0 0.056
disease of anatomical entity DOID:7 0 0.056
cardiovascular system disease DOID:1287 0 0.056
musculoskeletal system disease DOID:17 0 0.056
muscle tissue disease DOID:66 0 0.056
dilated cardiomyopathy DOID:12930 0 0.014
intrinsic cardiomyopathy DOID:0060036 0 0.014