Caenorhabditis elegans

33 known processes

plx-2 (CELE_K04B12.1)

Protein PLX-2

plx-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.459
embryo development GO:0009790 3052 0.330
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.314
establishment of localization GO:0051234 1171 0.281
locomotion GO:0040011 1634 0.279
localization of cell GO:0051674 313 0.235
regulation of developmental process GO:0050793 684 0.230
neuron projection extension involved in neuron projection guidance GO:1902284 13 0.211
embryo development ending in birth or egg hatching GO:0009792 2992 0.205
developmental process involved in reproduction GO:0003006 1165 0.205
positive regulation of multicellular organismal process GO:0051240 417 0.176
mesoderm development GO:0007498 27 0.173
anterior posterior axon guidance GO:0033564 5 0.153
regulation of macromolecule metabolic process GO:0060255 421 0.147
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.144
neuron projection morphogenesis GO:0048812 114 0.142
regulation of multicellular organismal development GO:2000026 317 0.142
regulation of multicellular organismal process GO:0051239 726 0.140
growth GO:0040007 562 0.140
transport GO:0006810 1093 0.139
cell motility GO:0048870 313 0.137
regulation of vulval development GO:0040028 248 0.136
endocytosis GO:0006897 819 0.127
body morphogenesis GO:0010171 620 0.126
response to chemical GO:0042221 356 0.125
neuron development GO:0048666 199 0.123
negative regulation of vulval development GO:0040027 206 0.121
regulation of developmental growth GO:0048638 389 0.120
negative regulation of developmental process GO:0051093 227 0.119
hermaphrodite genitalia development GO:0040035 734 0.118
organelle organization GO:0006996 783 0.117
regulation of biological quality GO:0065008 741 0.117
cell development GO:0048468 696 0.115
development of primary sexual characteristics GO:0045137 840 0.113
regulation of post embryonic development GO:0048580 260 0.111
negative regulation of multicellular organismal process GO:0051241 236 0.106
cellular nitrogen compound biosynthetic process GO:0044271 192 0.106
cell cycle process GO:0022402 482 0.104
multi organism behavior GO:0051705 389 0.102
nervous system development GO:0007399 253 0.102
axonogenesis GO:0007409 102 0.102
organ development GO:0048513 1102 0.101
positive regulation of developmental process GO:0051094 408 0.099
gonad development GO:0008406 840 0.097
regulation of neuron differentiation GO:0045664 40 0.096
cell fate commitment GO:0045165 139 0.096
vesicle mediated transport GO:0016192 852 0.095
neuron projection guidance GO:0097485 82 0.094
sex differentiation GO:0007548 909 0.094
macromolecule localization GO:0033036 771 0.090
post embryonic organ development GO:0048569 336 0.089
protein complex subunit organization GO:0071822 280 0.088
behavior GO:0007610 527 0.088
single organism organelle organization GO:1902589 501 0.087
regulation of nematode larval development GO:0061062 260 0.087
head development GO:0060322 1 0.085
developmental growth GO:0048589 412 0.082
positive regulation of growth GO:0045927 369 0.081
macromolecular complex subunit organization GO:0043933 320 0.080
cellular protein metabolic process GO:0044267 279 0.080
negative regulation of biological process GO:0048519 567 0.079
reproductive structure development GO:0048608 850 0.077
taxis GO:0042330 128 0.077
positive regulation of developmental growth GO:0048639 354 0.076
oviposition GO:0018991 364 0.076
reproductive system development GO:0061458 850 0.076
ovulation GO:0030728 33 0.076
programmed cell death GO:0012501 500 0.075
neuron differentiation GO:0030182 217 0.075
cellular macromolecule biosynthetic process GO:0034645 247 0.075
multi organism reproductive process GO:0044703 867 0.074
regulation of organelle organization GO:0033043 164 0.074
positive regulation of multicellular organism growth GO:0040018 352 0.074
vulval development GO:0040025 333 0.073
maintenance of location GO:0051235 580 0.071
gastrulation GO:0007369 58 0.071
multicellular organismal reproductive process GO:0048609 815 0.070
organelle fission GO:0048285 363 0.069
positive regulation of neurogenesis GO:0050769 4 0.069
neuron projection development GO:0031175 187 0.068
negative regulation of nematode larval development GO:0061064 208 0.068
multicellular organismal aging GO:0010259 812 0.067
lipid storage GO:0019915 565 0.066
organic substance biosynthetic process GO:1901576 323 0.066
cellular component movement GO:0006928 388 0.065
axon development GO:0061564 163 0.064
organelle localization GO:0051640 127 0.063
genitalia development GO:0048806 741 0.063
lipid localization GO:0010876 573 0.063
axon guidance GO:0007411 82 0.062
cell surface receptor signaling pathway GO:0007166 149 0.061
establishment of organelle localization GO:0051656 123 0.061
regulation of growth GO:0040008 409 0.059
positive regulation of gene expression GO:0010628 112 0.059
positive regulation of cellular biosynthetic process GO:0031328 109 0.058
cell migration GO:0016477 306 0.058
meiotic cell cycle GO:0051321 335 0.057
response to external stimulus GO:0009605 289 0.056
regulation of biosynthetic process GO:0009889 189 0.055
cytoskeleton organization GO:0007010 339 0.055
single organism signaling GO:0044700 401 0.054
generation of neurons GO:0048699 235 0.053
macromolecule biosynthetic process GO:0009059 250 0.052
regulation of multicellular organism growth GO:0040014 373 0.051
mesodermal cell migration GO:0008078 9 0.050
cell part morphogenesis GO:0032990 152 0.050
chemotaxis GO:0006935 120 0.049
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.049
cellular protein modification process GO:0006464 207 0.049
cell division GO:0051301 262 0.048
cell cycle GO:0007049 526 0.048
nematode male tail tip morphogenesis GO:0045138 77 0.048
rna metabolic process GO:0016070 228 0.047
cell morphogenesis involved in differentiation GO:0000904 112 0.047
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.047
single organism transport GO:0044765 447 0.047
neurogenesis GO:0022008 236 0.047
negative regulation of neurogenesis GO:0050768 4 0.046
multicellular organism growth GO:0035264 385 0.046
positive regulation of transcription dna templated GO:0045893 102 0.046
cell projection organization GO:0030030 231 0.046
cell death GO:0008219 547 0.045
single organism reproductive process GO:0044702 1196 0.045
mitotic nuclear division GO:0007067 89 0.044
regulation of macromolecule biosynthetic process GO:0010556 189 0.044
regulation of cell migration GO:0030334 55 0.044
dendrite development GO:0016358 42 0.044
cell morphogenesis GO:0000902 163 0.044
multicellular organismal reproductive behavior GO:0033057 384 0.043
aging GO:0007568 812 0.043
molting cycle GO:0042303 281 0.043
establishment of nucleus localization GO:0040023 55 0.042
nucleic acid metabolic process GO:0090304 299 0.042
protein localization GO:0008104 205 0.042
reproductive behavior GO:0019098 387 0.042
cellular component assembly GO:0022607 293 0.041
regulation of gene expression GO:0010468 366 0.040
gamete generation GO:0007276 461 0.040
regulation of response to stimulus GO:0048583 243 0.040
receptor mediated endocytosis GO:0006898 715 0.040
death GO:0016265 547 0.040
determination of adult lifespan GO:0008340 812 0.039
nucleus localization GO:0051647 55 0.039
mitotic cell cycle process GO:1903047 194 0.038
gene expression GO:0010467 412 0.037
apoptotic process GO:0006915 478 0.037
regulation of metabolic process GO:0019222 478 0.037
phagocytosis GO:0006909 115 0.037
positive regulation of biosynthetic process GO:0009891 109 0.036
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.036
muscle tissue development GO:0060537 1 0.036
organic substance catabolic process GO:1901575 294 0.035
regulation of cell development GO:0060284 49 0.035
canonical wnt signaling pathway GO:0060070 3 0.034
multi organism reproductive behavior GO:0044705 387 0.034
regulation of signaling GO:0023051 172 0.034
positive regulation of rna metabolic process GO:0051254 103 0.033
positive regulation of cellular metabolic process GO:0031325 178 0.033
regulation of locomotion GO:0040012 161 0.033
spindle organization GO:0007051 92 0.032
positive regulation of cellular process GO:0048522 332 0.032
multicellular organism reproduction GO:0032504 819 0.032
protein metabolic process GO:0019538 422 0.032
regulation of transcription dna templated GO:0006355 164 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.031
motor neuron axon guidance GO:0008045 13 0.031
negative regulation of cellular process GO:0048523 239 0.030
negative regulation of macromolecule metabolic process GO:0010605 229 0.030
pronuclear migration GO:0035046 51 0.030
organelle assembly GO:0070925 214 0.030
nucleobase containing compound biosynthetic process GO:0034654 184 0.029
multi multicellular organism process GO:0044706 390 0.029
organonitrogen compound metabolic process GO:1901564 151 0.029
positive regulation of neuron differentiation GO:0045666 4 0.029
macromolecular complex assembly GO:0065003 193 0.029
regulation of rna biosynthetic process GO:2001141 165 0.029
cellular component morphogenesis GO:0032989 318 0.029
germ cell development GO:0007281 351 0.029
regulation of cell differentiation GO:0045595 81 0.029
establishment of localization in cell GO:0051649 318 0.029
negative regulation of metabolic process GO:0009892 240 0.028
mesoderm morphogenesis GO:0048332 24 0.028
positive regulation of macromolecule metabolic process GO:0010604 149 0.028
regulation of rna metabolic process GO:0051252 173 0.028
male sex differentiation GO:0046661 86 0.028
regulation of signal transduction GO:0009966 135 0.027
inductive cell migration GO:0040039 145 0.026
female gamete generation GO:0007292 254 0.026
male anatomical structure morphogenesis GO:0090598 78 0.026
response to wounding GO:0009611 4 0.026
muscle structure development GO:0061061 191 0.026
positive regulation of rna biosynthetic process GO:1902680 102 0.026
cellular biosynthetic process GO:0044249 315 0.026
anatomical structure formation involved in morphogenesis GO:0048646 250 0.025
transcription from rna polymerase ii promoter GO:0006366 149 0.025
dorsal ventral axon guidance GO:0033563 19 0.025
regulation of cell motility GO:2000145 57 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.025
regulation of cellular component organization GO:0051128 248 0.025
transcription dna templated GO:0006351 168 0.024
regionalization GO:0003002 31 0.024
negative regulation of signaling GO:0023057 61 0.024
biosynthetic process GO:0009058 323 0.024
negative regulation of gene expression GO:0010629 217 0.024
regulation of localization GO:0032879 194 0.024
regulation of cell projection organization GO:0031344 38 0.024
heterocycle biosynthetic process GO:0018130 187 0.023
anterior posterior axis specification GO:0009948 17 0.023
digestive system development GO:0055123 122 0.023
aromatic compound biosynthetic process GO:0019438 192 0.023
single organism localization GO:1902578 518 0.023
regulation of cell cycle GO:0051726 194 0.023
meiotic cell cycle process GO:1903046 170 0.023
embryonic body morphogenesis GO:0010172 49 0.023
cell proliferation GO:0008283 116 0.023
axis specification GO:0009798 23 0.023
regulation of primary metabolic process GO:0080090 292 0.022
digestive tract development GO:0048565 122 0.022
mesodermal cell differentiation GO:0048333 15 0.022
actin filament based process GO:0030029 191 0.022
regulation of gene expression epigenetic GO:0040029 163 0.022
vesicle localization GO:0051648 24 0.021
regulation of canonical wnt signaling pathway GO:0060828 1 0.021
phosphorus metabolic process GO:0006793 232 0.021
signaling GO:0023052 401 0.021
tube development GO:0035295 126 0.021
epithelial tube morphogenesis GO:0060562 1 0.021
nuclear migration GO:0007097 54 0.020
positive regulation of response to stimulus GO:0048584 55 0.020
engulfment of apoptotic cell GO:0043652 94 0.020
phosphate containing compound metabolic process GO:0006796 232 0.020
intracellular signal transduction GO:0035556 96 0.020
positive regulation of nucleic acid templated transcription GO:1903508 102 0.020
muscle cell differentiation GO:0042692 171 0.020
regulation of cell proliferation GO:0042127 105 0.019
sensory organ morphogenesis GO:0090596 2 0.019
regulation of cellular metabolic process GO:0031323 305 0.019
regulation of neurogenesis GO:0050767 40 0.019
actomyosin structure organization GO:0031032 154 0.019
phosphorylation GO:0016310 116 0.019
embryonic morphogenesis GO:0048598 152 0.019
dna templated transcription elongation GO:0006354 1 0.018
cellular component biogenesis GO:0044085 297 0.018
cell projection morphogenesis GO:0048858 148 0.018
nucleic acid templated transcription GO:0097659 169 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.018
oogenesis GO:0048477 229 0.018
positive regulation of organ growth GO:0046622 4 0.018
actin cytoskeleton organization GO:0030036 184 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.018
regulation of nitrogen compound metabolic process GO:0051171 222 0.018
negative chemotaxis GO:0050919 1 0.018
nucleobase containing compound metabolic process GO:0006139 406 0.017
protein complex assembly GO:0006461 186 0.017
regulation of cell communication GO:0010646 176 0.017
gene silencing by rna GO:0031047 143 0.017
ion transport GO:0006811 113 0.017
positive regulation of metabolic process GO:0009893 187 0.017
regulation of cellular component movement GO:0051270 62 0.017
cellular component assembly involved in morphogenesis GO:0010927 183 0.017
cellular localization GO:0051641 360 0.016
signal transduction GO:0007165 317 0.016
regulation of phosphorylation GO:0042325 45 0.016
neuron projection extension GO:1990138 37 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.016
apoptotic cell clearance GO:0043277 111 0.016
regulation of phosphorus metabolic process GO:0051174 81 0.016
posttranscriptional gene silencing by rna GO:0035194 143 0.016
epithelial cell proliferation GO:0050673 1 0.016
regulation of cation channel activity GO:2001257 3 0.015
axon extension involved in axon guidance GO:0048846 13 0.015
regulation of cell division GO:0051302 142 0.015
catabolic process GO:0009056 318 0.015
protein catabolic process GO:0030163 162 0.015
organic cyclic compound biosynthetic process GO:1901362 195 0.015
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.015
macromolecule modification GO:0043412 218 0.015
neuron fate specification GO:0048665 8 0.015
small gtpase mediated signal transduction GO:0007264 32 0.015
tube morphogenesis GO:0035239 79 0.015
membrane organization GO:0061024 135 0.015
positive regulation of cell projection organization GO:0031346 4 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
negative regulation of transporter activity GO:0032410 3 0.015
regulation of cytoskeleton organization GO:0051493 41 0.014
negative regulation of post embryonic development GO:0048581 208 0.014
tissue development GO:0009888 112 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
response to external biotic stimulus GO:0043207 101 0.014
rna biosynthetic process GO:0032774 169 0.014
regulation of organ morphogenesis GO:2000027 4 0.014
inactivation of mapkkk activity GO:0051390 2 0.014
sexual reproduction GO:0019953 546 0.014
positive regulation of cell communication GO:0010647 69 0.014
germ line sex determination GO:0018992 51 0.014
phagocytosis engulfment GO:0006911 98 0.014
pattern specification process GO:0007389 59 0.014
protein modification process GO:0036211 207 0.013
wnt signaling pathway GO:0016055 27 0.013
axon extension GO:0048675 37 0.013
regulation of cell death GO:0010941 65 0.013
muscle cell development GO:0055001 158 0.013
lipid metabolic process GO:0006629 77 0.013
digestive tract morphogenesis GO:0048546 76 0.013
regulation of behavior GO:0050795 97 0.013
regulation of cellular protein metabolic process GO:0032268 75 0.013
mitotic spindle organization GO:0007052 81 0.013
mating behavior GO:0007617 32 0.013
lamellipodium assembly GO:0030032 2 0.013
muscle organ morphogenesis GO:0048644 4 0.013
male mating behavior GO:0060179 26 0.013
transmembrane transport GO:0055085 110 0.012
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.012
striated muscle cell differentiation GO:0051146 158 0.012
stem cell proliferation GO:0072089 9 0.012
cell type specific apoptotic process GO:0097285 4 0.012
epithelial cell differentiation GO:0030855 17 0.012
regulation of programmed cell death GO:0043067 50 0.012
membrane invagination GO:0010324 98 0.012
positive regulation of neuron projection development GO:0010976 4 0.012
centrosomal and pronuclear rotation GO:0035047 6 0.012
regulation of cell projection assembly GO:0060491 3 0.012
anterior posterior pattern specification GO:0009952 27 0.012
chromosome organization GO:0051276 104 0.012
regulation of lipid metabolic process GO:0019216 4 0.012
negative regulation of axonogenesis GO:0050771 2 0.012
negative regulation of neuron differentiation GO:0045665 4 0.011
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 35 0.011
negative regulation of cell communication GO:0010648 61 0.011
sex determination GO:0007530 60 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
regulation of actin filament based process GO:0032970 22 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of cell cycle process GO:0010564 145 0.011
cellular response to stress GO:0033554 162 0.011
single fertilization GO:0007338 61 0.011
negative regulation of biosynthetic process GO:0009890 65 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
epithelium development GO:0060429 68 0.011
negative regulation of cellular component organization GO:0051129 33 0.011
regulation of nervous system development GO:0051960 41 0.010
regulation of epithelial cell proliferation GO:0050678 1 0.010
regulation of mitotic cell cycle GO:0007346 76 0.010
posttranscriptional gene silencing GO:0016441 143 0.010
system process GO:0003008 136 0.010
regulation of small gtpase mediated signal transduction GO:0051056 41 0.010
negative regulation of locomotion GO:0040013 21 0.010
myofibril assembly GO:0030239 154 0.010
actin filament bundle assembly GO:0051017 3 0.010

plx-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.013