Caenorhabditis elegans

0 known processes

pme-1 (CELE_Y71F9AL.18)

Protein PME-1

pme-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.743
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.472
Worm
single organism localization GO:1902578 518 0.399
single organism organelle organization GO:1902589 501 0.364
Mouse
phosphorus metabolic process GO:0006793 232 0.311
mitotic nuclear division GO:0007067 89 0.258
sister chromatid segregation GO:0000819 46 0.241
cell cycle process GO:0022402 482 0.228
development of primary sexual characteristics GO:0045137 840 0.223
cell cycle GO:0007049 526 0.212
phosphate containing compound metabolic process GO:0006796 232 0.210
organelle organization GO:0006996 783 0.202
Mouse
cellular response to dna damage stimulus GO:0006974 41 0.192
Human Mouse
genitalia development GO:0048806 741 0.181
biosynthetic process GO:0009058 323 0.180
Human
nucleotide metabolic process GO:0009117 108 0.179
gonad development GO:0008406 840 0.169
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.160
cellular localization GO:0051641 360 0.159
reproductive system development GO:0061458 850 0.158
carbohydrate derivative metabolic process GO:1901135 141 0.154
Human
establishment of localization in cell GO:0051649 318 0.150
nucleoside phosphate metabolic process GO:0006753 108 0.150
purine containing compound catabolic process GO:0072523 75 0.149
sex differentiation GO:0007548 909 0.140
mitotic sister chromatid segregation GO:0000070 38 0.138
macromolecule localization GO:0033036 771 0.137
nucleobase containing small molecule metabolic process GO:0055086 115 0.133
organic substance biosynthetic process GO:1901576 323 0.131
Human
actin cytoskeleton organization GO:0030036 184 0.131
catabolic process GO:0009056 318 0.129
regulation of macromolecule metabolic process GO:0060255 421 0.126
developmental process involved in reproduction GO:0003006 1165 0.123
organelle fission GO:0048285 363 0.122
heterocycle catabolic process GO:0046700 119 0.116
locomotion GO:0040011 1634 0.114
ribonucleoside triphosphate metabolic process GO:0009199 87 0.114
purine ribonucleotide metabolic process GO:0009150 95 0.113
organonitrogen compound metabolic process GO:1901564 151 0.113
nucleoside phosphate catabolic process GO:1901292 77 0.110
single organism signaling GO:0044700 401 0.108
nucleoside catabolic process GO:0009164 78 0.107
ribonucleoside monophosphate metabolic process GO:0009161 45 0.107
ribonucleotide catabolic process GO:0009261 75 0.106
chromosome segregation GO:0007059 180 0.101
transport GO:0006810 1093 0.101
nucleobase containing compound biosynthetic process GO:0034654 184 0.100
single organism reproductive process GO:0044702 1196 0.099
endocytosis GO:0006897 819 0.095
establishment of localization GO:0051234 1171 0.095
glycosyl compound metabolic process GO:1901657 100 0.093
nucleoside triphosphate catabolic process GO:0009143 72 0.091
signaling GO:0023052 401 0.090
purine nucleoside triphosphate catabolic process GO:0009146 72 0.090
purine nucleoside triphosphate metabolic process GO:0009144 87 0.090
organonitrogen compound catabolic process GO:1901565 90 0.089
mitotic cell cycle process GO:1903047 194 0.089
cell death GO:0008219 547 0.088
Worm
regulation of biological quality GO:0065008 741 0.087
Mouse
hermaphrodite genitalia development GO:0040035 734 0.086
regulation of cellular metabolic process GO:0031323 305 0.086
organophosphate metabolic process GO:0019637 125 0.084
ribose phosphate metabolic process GO:0019693 99 0.084
purine nucleotide catabolic process GO:0006195 75 0.084
multi organism behavior GO:0051705 389 0.083
carbohydrate derivative catabolic process GO:1901136 82 0.083
multicellular organismal reproductive behavior GO:0033057 384 0.080
multi multicellular organism process GO:0044706 390 0.079
receptor mediated endocytosis GO:0006898 715 0.079
cellular biosynthetic process GO:0044249 315 0.079
Human
small molecule metabolic process GO:0044281 186 0.079
maintenance of location GO:0051235 580 0.078
post embryonic development GO:0009791 2152 0.077
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.076
glycosyl compound catabolic process GO:1901658 79 0.076
multi organism reproductive behavior GO:0044705 387 0.075
positive regulation of cellular process GO:0048522 332 0.075
lipid storage GO:0019915 565 0.074
atp metabolic process GO:0046034 42 0.073
behavior GO:0007610 527 0.070
dna metabolic process GO:0006259 74 0.070
Human Mouse
protein complex subunit organization GO:0071822 280 0.068
ribonucleoside metabolic process GO:0009119 98 0.067
organic substance catabolic process GO:1901575 294 0.066
organ development GO:0048513 1102 0.066
phosphorylation GO:0016310 116 0.065
reproductive behavior GO:0019098 387 0.065
dna repair GO:0006281 23 0.063
Human Mouse
multicellular organismal reproductive process GO:0048609 815 0.062
lipid localization GO:0010876 573 0.062
purine containing compound metabolic process GO:0072521 95 0.060
negative regulation of biological process GO:0048519 567 0.059
Worm
chromosome organization GO:0051276 104 0.058
Mouse
macromolecule catabolic process GO:0009057 202 0.058
organic cyclic compound catabolic process GO:1901361 119 0.057
regulation of primary metabolic process GO:0080090 292 0.056
nucleoside metabolic process GO:0009116 99 0.055
nucleotide catabolic process GO:0009166 77 0.055
regulation of multicellular organismal process GO:0051239 726 0.054
organophosphate catabolic process GO:0046434 81 0.053
single organism transport GO:0044765 447 0.052
purine ribonucleotide catabolic process GO:0009154 75 0.051
multicellular organismal aging GO:0010259 812 0.051
purine nucleotide metabolic process GO:0006163 95 0.050
regulation of multicellular organism growth GO:0040014 373 0.050
purine ribonucleoside metabolic process GO:0046128 92 0.050
vesicle mediated transport GO:0016192 852 0.049
cytoskeleton organization GO:0007010 339 0.049
rna localization GO:0006403 3 0.049
oviposition GO:0018991 364 0.048
cellular response to stress GO:0033554 162 0.048
Human Mouse
organelle localization GO:0051640 127 0.048
cellular component assembly GO:0022607 293 0.048
cellular component morphogenesis GO:0032989 318 0.047
cellular protein complex assembly GO:0043623 178 0.047
signal transduction GO:0007165 317 0.047
determination of adult lifespan GO:0008340 812 0.047
meiotic cell cycle process GO:1903046 170 0.047
nucleoside monophosphate metabolic process GO:0009123 46 0.046
multi organism reproductive process GO:0044703 867 0.046
cellular component biogenesis GO:0044085 297 0.045
cellular macromolecule biosynthetic process GO:0034645 247 0.045
Human
macromolecular complex assembly GO:0065003 193 0.044
ribonucleotide metabolic process GO:0009259 99 0.044
ribonucleoside triphosphate catabolic process GO:0009203 72 0.044
regulation of signaling GO:0023051 172 0.043
protein complex biogenesis GO:0070271 186 0.042
protein localization GO:0008104 205 0.042
purine nucleoside catabolic process GO:0006152 75 0.042
protein complex assembly GO:0006461 186 0.042
cellular component movement GO:0006928 388 0.041
positive regulation of macromolecule metabolic process GO:0010604 149 0.040
actin filament based process GO:0030029 191 0.039
negative regulation of nucleoside metabolic process GO:0045978 5 0.039
heterocycle biosynthetic process GO:0018130 187 0.038
regulation of signal transduction GO:0009966 135 0.037
ribonucleoside catabolic process GO:0042454 77 0.037
reproductive structure development GO:0048608 850 0.036
protein catabolic process GO:0030163 162 0.036
nitrogen compound transport GO:0071705 49 0.035
regulation of rna metabolic process GO:0051252 173 0.034
meiotic nuclear division GO:0007126 300 0.034
aromatic compound catabolic process GO:0019439 116 0.034
membrane organization GO:0061024 135 0.034
single organism catabolic process GO:0044712 129 0.034
cellular macromolecular complex assembly GO:0034622 184 0.034
regulation of cell morphogenesis GO:0022604 40 0.034
anatomical structure formation involved in morphogenesis GO:0048646 250 0.033
regulation of developmental process GO:0050793 684 0.033
cell development GO:0048468 696 0.033
regulation of metabolic process GO:0019222 478 0.033
nervous system development GO:0007399 253 0.032
positive regulation of developmental growth GO:0048639 354 0.032
generation of neurons GO:0048699 235 0.032
protein metabolic process GO:0019538 422 0.032
Human
organelle assembly GO:0070925 214 0.032
regulation of developmental growth GO:0048638 389 0.031
regulation of cell communication GO:0010646 176 0.031
death GO:0016265 547 0.031
Worm
regulation of cell cycle process GO:0010564 145 0.030
positive regulation of metabolic process GO:0009893 187 0.030
cellular nitrogen compound biosynthetic process GO:0044271 192 0.030
cellular nitrogen compound catabolic process GO:0044270 119 0.029
cell division GO:0051301 262 0.029
macromolecule biosynthetic process GO:0009059 250 0.028
Human
developmental growth GO:0048589 412 0.028
actomyosin structure organization GO:0031032 154 0.028
nucleobase containing compound catabolic process GO:0034655 114 0.028
regulation of macromolecule biosynthetic process GO:0010556 189 0.027
regulation of gene expression GO:0010468 366 0.027
nucleoside triphosphate metabolic process GO:0009141 87 0.027
ras protein signal transduction GO:0007265 31 0.027
positive regulation of developmental process GO:0051094 408 0.027
regulation of nitrogen compound metabolic process GO:0051171 222 0.026
multicellular organism reproduction GO:0032504 819 0.026
regulation of cellular protein metabolic process GO:0032268 75 0.026
dna conformation change GO:0071103 11 0.026
regulation of multicellular organismal development GO:2000026 317 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.025
cell projection organization GO:0030030 231 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.024
regulation of nucleoside metabolic process GO:0009118 37 0.023
dna duplex unwinding GO:0032508 3 0.023
regulation of purine nucleotide catabolic process GO:0033121 35 0.023
aging GO:0007568 812 0.023
spindle localization GO:0051653 51 0.023
rna biosynthetic process GO:0032774 169 0.022
macromolecular complex subunit organization GO:0043933 320 0.022
oocyte construction GO:0007308 2 0.021
positive regulation of growth GO:0045927 369 0.021
aromatic compound biosynthetic process GO:0019438 192 0.021
secretion GO:0046903 147 0.021
purine nucleoside monophosphate catabolic process GO:0009128 28 0.021
response to chemical GO:0042221 356 0.021
Human Mouse
purine nucleoside metabolic process GO:0042278 92 0.021
regulation of phosphorus metabolic process GO:0051174 81 0.021
regulation of intracellular signal transduction GO:1902531 77 0.020
single organism biosynthetic process GO:0044711 91 0.020
striated muscle myosin thick filament assembly GO:0071688 138 0.020
negative regulation of cellular process GO:0048523 239 0.020
Worm
meiotic chromosome segregation GO:0045132 139 0.020
establishment of organelle localization GO:0051656 123 0.020
cell projection morphogenesis GO:0048858 148 0.020
myofibril assembly GO:0030239 154 0.019
regulation of nucleic acid templated transcription GO:1903506 165 0.019
guanosine containing compound catabolic process GO:1901069 48 0.019
oogenesis GO:0048477 229 0.019
female gamete generation GO:0007292 254 0.019
purine ribonucleoside catabolic process GO:0046130 75 0.019
regulation of nucleotide metabolic process GO:0006140 37 0.019
negative regulation of metabolic process GO:0009892 240 0.019
response to external stimulus GO:0009605 289 0.019
adult behavior GO:0030534 3 0.018
growth GO:0040007 562 0.018
Mouse
apoptotic process GO:0006915 478 0.018
positive regulation of cellular metabolic process GO:0031325 178 0.018
response to abiotic stimulus GO:0009628 152 0.018
nucleobase containing compound metabolic process GO:0006139 406 0.018
Human Mouse
organic cyclic compound biosynthetic process GO:1901362 195 0.018
synaptic transmission GO:0007268 106 0.018
germ cell development GO:0007281 351 0.018
regulation of reproductive process GO:2000241 66 0.017
body morphogenesis GO:0010171 620 0.017
positive regulation of multicellular organism growth GO:0040018 352 0.017
microtubule based process GO:0007017 182 0.017
cellular catabolic process GO:0044248 199 0.017
cellular protein localization GO:0034613 75 0.017
spindle organization GO:0007051 92 0.017
positive regulation of small gtpase mediated signal transduction GO:0051057 7 0.017
dna recombination GO:0006310 19 0.017
cellular amine metabolic process GO:0044106 15 0.017
chromosome organization involved in meiosis GO:0070192 25 0.017
positive regulation of multicellular organismal process GO:0051240 417 0.017
atp catabolic process GO:0006200 27 0.016
regulation of cell cycle GO:0051726 194 0.016
dna geometric change GO:0032392 3 0.016
cell cell signaling GO:0007267 118 0.016
regulation of catabolic process GO:0009894 57 0.016
membrane invagination GO:0010324 98 0.016
regulation of locomotion GO:0040012 161 0.015
localization of cell GO:0051674 313 0.015
positive regulation of cell communication GO:0010647 69 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
negative regulation of purine nucleotide metabolic process GO:1900543 5 0.015
protein oligomerization GO:0051259 4 0.015
innate immune response GO:0045087 190 0.015
myosin filament organization GO:0031033 138 0.015
meiotic sister chromatid segregation GO:0045144 15 0.015
positive regulation of intracellular signal transduction GO:1902533 24 0.015
negative regulation of cell cycle GO:0045786 53 0.015
phagocytosis engulfment GO:0006911 98 0.015
organic substance transport GO:0071702 113 0.015
rna interference GO:0016246 137 0.015
meiotic cell cycle GO:0051321 335 0.014
positive regulation of signaling GO:0023056 66 0.014
regulation of biosynthetic process GO:0009889 189 0.014
negative regulation of post embryonic development GO:0048581 208 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.014
regulation of phosphate metabolic process GO:0019220 81 0.014
cellular response to inorganic substance GO:0071241 3 0.014
negative regulation of macromolecule metabolic process GO:0010605 229 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.014
system process GO:0003008 136 0.014
myosin filament assembly GO:0031034 138 0.014
actin cytoskeleton reorganization GO:0031532 4 0.014
neuron projection development GO:0031175 187 0.014
positive regulation of stem cell differentiation GO:2000738 1 0.014
intracellular signal transduction GO:0035556 96 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.013
regulation of cellular component organization GO:0051128 248 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.013
regulation of nucleotide catabolic process GO:0030811 35 0.013
pole plasm assembly GO:0007315 2 0.013
regulation of ras gtpase activity GO:0032318 21 0.013
gene silencing by rna GO:0031047 143 0.013
regulation of post embryonic development GO:0048580 260 0.013
base excision repair GO:0006284 4 0.013
Mouse
tissue development GO:0009888 112 0.013
multicellular organism growth GO:0035264 385 0.013
regulation of cell division GO:0051302 142 0.013
negative regulation of nematode larval development GO:0061064 208 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
negative regulation of cellular biosynthetic process GO:0031327 65 0.012
regulation of growth GO:0040008 409 0.012
Mouse
vulval development GO:0040025 333 0.012
striated muscle cell differentiation GO:0051146 158 0.012
intracellular transport GO:0046907 77 0.012
positive regulation of gene expression GO:0010628 112 0.012
cell morphogenesis GO:0000902 163 0.012
regulation of cellular biosynthetic process GO:0031326 189 0.012
muscle structure development GO:0061061 191 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
cell morphogenesis involved in differentiation GO:0000904 112 0.012
regulation of chromosome segregation GO:0051983 20 0.012
regulation of vulval development GO:0040028 248 0.011
establishment of rna localization GO:0051236 3 0.011
dna topological change GO:0006265 1 0.011
nucleic acid metabolic process GO:0090304 299 0.011
Human Mouse
head development GO:0060322 1 0.011
cytoskeleton dependent cytokinesis GO:0061640 35 0.011
posttranscriptional gene silencing by rna GO:0035194 143 0.011
regulation of purine nucleotide metabolic process GO:1900542 37 0.011
regulation of gene expression epigenetic GO:0040029 163 0.011
regulation of cell projection organization GO:0031344 38 0.011
transcription from rna polymerase ii promoter GO:0006366 149 0.011
detection of external stimulus GO:0009581 4 0.011
regulation of chromosome organization GO:0033044 20 0.011
regulation of response to stimulus GO:0048583 243 0.011
regulation of organelle organization GO:0033043 164 0.011
fertilization GO:0009566 63 0.011
neuron development GO:0048666 199 0.011
hormone secretion GO:0046879 2 0.011
regulation of hydrolase activity GO:0051336 45 0.011
posttranscriptional gene silencing GO:0016441 143 0.010
regulation of transcription dna templated GO:0006355 164 0.010
cell surface receptor signaling pathway GO:0007166 149 0.010
neuron projection extension involved in neuron projection guidance GO:1902284 13 0.010
ribonucleoside monophosphate catabolic process GO:0009158 28 0.010
telomere organization GO:0032200 6 0.010
Mouse
transcription dna templated GO:0006351 168 0.010
regulation of localization GO:0032879 194 0.010

pme-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.046
cancer DOID:162 0 0.026
organ system cancer DOID:0050686 0 0.026