Caenorhabditis elegans

30 known processes

klf-1 (CELE_F56F11.3)

Protein KLF-1

klf-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.211
post embryonic development GO:0009791 2152 0.155
Worm
embryo development GO:0009790 3052 0.150
post embryonic organ development GO:0048569 336 0.105
Worm
locomotion GO:0040011 1634 0.104
Worm
regulation of developmental process GO:0050793 684 0.093
single organism reproductive process GO:0044702 1196 0.089
positive regulation of multicellular organismal process GO:0051240 417 0.084
receptor mediated endocytosis GO:0006898 715 0.082
death GO:0016265 547 0.079
macromolecule localization GO:0033036 771 0.077
regulation of multicellular organismal process GO:0051239 726 0.077
regulation of biological quality GO:0065008 741 0.077
development of primary sexual characteristics GO:0045137 840 0.074
aging GO:0007568 812 0.074
determination of adult lifespan GO:0008340 812 0.072
endocytosis GO:0006897 819 0.070
regulation of nematode larval development GO:0061062 260 0.070
organ development GO:0048513 1102 0.069
Worm
lipid storage GO:0019915 565 0.064
maintenance of location GO:0051235 580 0.063
establishment of localization GO:0051234 1171 0.063
reproductive structure development GO:0048608 850 0.062
reproductive system development GO:0061458 850 0.062
lipid localization GO:0010876 573 0.062
genitalia development GO:0048806 741 0.061
gonad development GO:0008406 840 0.061
multicellular organismal aging GO:0010259 812 0.060
developmental process involved in reproduction GO:0003006 1165 0.059
behavior GO:0007610 527 0.059
positive regulation of developmental process GO:0051094 408 0.057
sex differentiation GO:0007548 909 0.057
regulation of vulval development GO:0040028 248 0.056
multi organism reproductive process GO:0044703 867 0.056
multicellular organism growth GO:0035264 385 0.056
regulation of post embryonic development GO:0048580 260 0.055
head development GO:0060322 1 0.054
hermaphrodite genitalia development GO:0040035 734 0.053
organelle organization GO:0006996 783 0.052
vulval development GO:0040025 333 0.050
Worm
positive regulation of developmental growth GO:0048639 354 0.049
regulation of developmental growth GO:0048638 389 0.047
regulation of growth GO:0040008 409 0.047
cell death GO:0008219 547 0.047
cell cycle process GO:0022402 482 0.047
signaling GO:0023052 401 0.046
regulation of multicellular organism growth GO:0040014 373 0.046
regulation of macromolecule metabolic process GO:0060255 421 0.044
transport GO:0006810 1093 0.044
positive regulation of growth GO:0045927 369 0.044
multicellular organismal reproductive process GO:0048609 815 0.044
developmental growth GO:0048589 412 0.044
positive regulation of multicellular organism growth GO:0040018 352 0.043
multi organism reproductive behavior GO:0044705 387 0.043
organelle fission GO:0048285 363 0.043
multi multicellular organism process GO:0044706 390 0.043
regulation of multicellular organismal development GO:2000026 317 0.042
regulation of nitrogen compound metabolic process GO:0051171 222 0.042
cellular component morphogenesis GO:0032989 318 0.042
single organism signaling GO:0044700 401 0.041
cellular biosynthetic process GO:0044249 315 0.041
single organism organelle organization GO:1902589 501 0.041
regulation of macromolecule biosynthetic process GO:0010556 189 0.041
vesicle mediated transport GO:0016192 852 0.040
growth GO:0040007 562 0.040
neuron projection development GO:0031175 187 0.040
body morphogenesis GO:0010171 620 0.040
negative regulation of biological process GO:0048519 567 0.040
small molecule metabolic process GO:0044281 186 0.039
oviposition GO:0018991 364 0.039
oxoacid metabolic process GO:0043436 47 0.039
reproductive behavior GO:0019098 387 0.039
catabolic process GO:0009056 318 0.037
Worm
multicellular organism reproduction GO:0032504 819 0.037
regulation of metabolic process GO:0019222 478 0.036
protein metabolic process GO:0019538 422 0.036
Worm
regulation of cellular metabolic process GO:0031323 305 0.036
cellular macromolecule biosynthetic process GO:0034645 247 0.035
multicellular organismal reproductive behavior GO:0033057 384 0.035
nucleobase containing compound metabolic process GO:0006139 406 0.034
positive regulation of nematode larval development GO:0061063 54 0.034
multi organism behavior GO:0051705 389 0.033
signal transduction GO:0007165 317 0.033
gene expression GO:0010467 412 0.033
axonogenesis GO:0007409 102 0.033
programmed cell death GO:0012501 500 0.032
negative regulation of developmental process GO:0051093 227 0.032
cell fate commitment GO:0045165 139 0.032
regulation of primary metabolic process GO:0080090 292 0.031
cell migration GO:0016477 306 0.031
response to chemical GO:0042221 356 0.031
organic substance biosynthetic process GO:1901576 323 0.030
cell development GO:0048468 696 0.030
positive regulation of vulval development GO:0040026 52 0.030
negative regulation of nematode larval development GO:0061064 208 0.030
cellular component movement GO:0006928 388 0.030
negative regulation of macromolecule metabolic process GO:0010605 229 0.029
negative regulation of metabolic process GO:0009892 240 0.029
germ cell development GO:0007281 351 0.029
negative regulation of gene expression GO:0010629 217 0.029
negative regulation of post embryonic development GO:0048581 208 0.029
carboxylic acid metabolic process GO:0019752 34 0.029
positive regulation of neurogenesis GO:0050769 4 0.029
response to external stimulus GO:0009605 289 0.028
neuron projection morphogenesis GO:0048812 114 0.028
biosynthetic process GO:0009058 323 0.028
negative regulation of vulval development GO:0040027 206 0.028
regulation of gene expression GO:0010468 366 0.028
defense response GO:0006952 296 0.028
Worm
regulation of response to stimulus GO:0048583 243 0.028
cellular component biogenesis GO:0044085 297 0.027
organic acid metabolic process GO:0006082 47 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.027
positive regulation of cellular process GO:0048522 332 0.027
posttranscriptional regulation of gene expression GO:0010608 166 0.026
cellular protein metabolic process GO:0044267 279 0.026
positive regulation of macromolecule metabolic process GO:0010604 149 0.026
localization of cell GO:0051674 313 0.026
organonitrogen compound metabolic process GO:1901564 151 0.026
regulation of cell communication GO:0010646 176 0.025
response to abiotic stimulus GO:0009628 152 0.025
regulation of cellular biosynthetic process GO:0031326 189 0.024
positive regulation of neuron differentiation GO:0045666 4 0.024
regulation of localization GO:0032879 194 0.023
cell division GO:0051301 262 0.023
regulation of nucleic acid templated transcription GO:1903506 165 0.023
negative regulation of multicellular organismal process GO:0051241 236 0.023
cellular nitrogen compound biosynthetic process GO:0044271 192 0.023
meiotic cell cycle GO:0051321 335 0.022
cellular catabolic process GO:0044248 199 0.022
gamete generation GO:0007276 461 0.022
cytoskeleton organization GO:0007010 339 0.022
cell projection morphogenesis GO:0048858 148 0.022
cell cycle GO:0007049 526 0.022
rna biosynthetic process GO:0032774 169 0.022
rna metabolic process GO:0016070 228 0.022
cell motility GO:0048870 313 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.021
negative regulation of cellular process GO:0048523 239 0.021
cellular component assembly GO:0022607 293 0.021
axon development GO:0061564 163 0.021
organelle assembly GO:0070925 214 0.021
cellular response to stress GO:0033554 162 0.021
sensory organ morphogenesis GO:0090596 2 0.021
macromolecule biosynthetic process GO:0009059 250 0.021
sexual reproduction GO:0019953 546 0.021
nucleobase containing compound biosynthetic process GO:0034654 184 0.021
regulation of cellular component organization GO:0051128 248 0.020
macromolecule modification GO:0043412 218 0.020
immune response GO:0006955 192 0.020
Worm
female gamete generation GO:0007292 254 0.020
neurogenesis GO:0022008 236 0.019
actin cytoskeleton organization GO:0030036 184 0.019
organic substance catabolic process GO:1901575 294 0.019
Worm
oogenesis GO:0048477 229 0.019
digestive system development GO:0055123 122 0.019
posttranscriptional gene silencing by rna GO:0035194 143 0.019
regulation of lipid metabolic process GO:0019216 4 0.019
cell projection organization GO:0030030 231 0.019
regulation of signaling GO:0023051 172 0.019
regulation of cell division GO:0051302 142 0.019
regulation of locomotion GO:0040012 161 0.019
gene silencing by rna GO:0031047 143 0.019
macromolecular complex subunit organization GO:0043933 320 0.019
striated muscle cell differentiation GO:0051146 158 0.019
positive regulation of post embryonic development GO:0048582 54 0.018
molting cycle GO:0042303 281 0.018
generation of neurons GO:0048699 235 0.018
muscle cell differentiation GO:0042692 171 0.018
macromolecular complex assembly GO:0065003 193 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.018
meiotic nuclear division GO:0007126 300 0.018
taxis GO:0042330 128 0.018
cellular response to chemical stimulus GO:0070887 129 0.018
apoptotic process GO:0006915 478 0.018
protein complex subunit organization GO:0071822 280 0.018
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.017
phosphate containing compound metabolic process GO:0006796 232 0.017
heterocycle biosynthetic process GO:0018130 187 0.017
protein complex biogenesis GO:0070271 186 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
cellular protein modification process GO:0006464 207 0.017
cellular component assembly involved in morphogenesis GO:0010927 183 0.017
nucleic acid metabolic process GO:0090304 299 0.017
myofibril assembly GO:0030239 154 0.017
regulation of transcription dna templated GO:0006355 164 0.017
regulation of rna metabolic process GO:0051252 173 0.017
anatomical structure formation involved in morphogenesis GO:0048646 250 0.017
rna interference GO:0016246 137 0.017
regulation of epithelial cell proliferation GO:0050678 1 0.017
regulation of cell cycle GO:0051726 194 0.017
aromatic compound biosynthetic process GO:0019438 192 0.017
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.017
cell morphogenesis GO:0000902 163 0.017
establishment of localization in cell GO:0051649 318 0.017
organic cyclic compound biosynthetic process GO:1901362 195 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.016
cell proliferation GO:0008283 116 0.016
microtubule based process GO:0007017 182 0.016
nervous system development GO:0007399 253 0.016
gene silencing GO:0016458 143 0.016
tube development GO:0035295 126 0.016
muscle cell development GO:0055001 158 0.016
inductive cell migration GO:0040039 145 0.016
neuron development GO:0048666 199 0.016
posttranscriptional gene silencing GO:0016441 143 0.016
cellular ketone metabolic process GO:0042180 14 0.015
regulation of organelle organization GO:0033043 164 0.015
cellular localization GO:0051641 360 0.015
actomyosin structure organization GO:0031032 154 0.015
epithelial cell proliferation GO:0050673 1 0.015
protein phosphorylation GO:0006468 85 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
cell type specific apoptotic process GO:0097285 4 0.015
response to wounding GO:0009611 4 0.015
regulation of gene expression epigenetic GO:0040029 163 0.015
cellular macromolecular complex assembly GO:0034622 184 0.015
cellular response to organic substance GO:0071310 119 0.015
organophosphate metabolic process GO:0019637 125 0.015
regulation of cell proliferation GO:0042127 105 0.015
dauer larval development GO:0040024 92 0.015
transcription from rna polymerase ii promoter GO:0006366 149 0.015
positive regulation of metabolic process GO:0009893 187 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
cellular amino acid metabolic process GO:0006520 15 0.014
actin filament based process GO:0030029 191 0.014
phosphorus metabolic process GO:0006793 232 0.014
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.014
regulation of cell cycle process GO:0010564 145 0.014
regulation of biosynthetic process GO:0009889 189 0.014
establishment or maintenance of cell polarity GO:0007163 63 0.014
myosin filament assembly GO:0031034 138 0.014
regulation of anatomical structure size GO:0090066 46 0.014
single organism localization GO:1902578 518 0.014
protein complex assembly GO:0006461 186 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
digestive tract development GO:0048565 122 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
nucleic acid templated transcription GO:0097659 169 0.013
positive regulation of intracellular transport GO:0032388 2 0.013
protein catabolic process GO:0030163 162 0.013
Worm
positive regulation of neuron projection development GO:0010976 4 0.013
cellular protein complex assembly GO:0043623 178 0.013
regulation of organ morphogenesis GO:2000027 4 0.013
cellular response to abiotic stimulus GO:0071214 4 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
detection of external stimulus GO:0009581 4 0.013
protein modification process GO:0036211 207 0.013
innate immune response GO:0045087 190 0.013
Worm
intracellular signal transduction GO:0035556 96 0.013
regulation of lipid biosynthetic process GO:0046890 1 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.013
establishment of protein localization to membrane GO:0090150 3 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.013
regulation of cell differentiation GO:0045595 81 0.013
development of primary male sexual characteristics GO:0046546 4 0.013
apoptotic cell clearance GO:0043277 111 0.013
regeneration GO:0031099 4 0.013
response to temperature stimulus GO:0009266 66 0.013
single organism biosynthetic process GO:0044711 91 0.013
negative regulation of cell communication GO:0010648 61 0.013
striated muscle cell development GO:0055002 157 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
small molecule biosynthetic process GO:0044283 38 0.013
cellular amine metabolic process GO:0044106 15 0.013
male anatomical structure morphogenesis GO:0090598 78 0.013
positive regulation of biosynthetic process GO:0009891 109 0.013
defense response to gram negative bacterium GO:0050829 64 0.013
neuron recognition GO:0008038 83 0.013
positive regulation of cell communication GO:0010647 69 0.013
tube morphogenesis GO:0035239 79 0.013
lipid metabolic process GO:0006629 77 0.012
system process GO:0003008 136 0.012
chemotaxis GO:0006935 120 0.012
chromosome segregation GO:0007059 180 0.012
myosin filament organization GO:0031033 138 0.012
negative regulation of cellular metabolic process GO:0031324 95 0.012
neuromuscular junction development GO:0007528 2 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
muscle structure development GO:0061061 191 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
negative regulation of signal transduction GO:0009968 60 0.012
positive regulation of signaling GO:0023056 66 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.012
regulation of cellular catabolic process GO:0031329 51 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
adult behavior GO:0030534 3 0.012
cell recognition GO:0008037 85 0.012
cuticle development GO:0042335 100 0.011
g protein coupled receptor signaling pathway GO:0007186 46 0.011
positive regulation of cell projection organization GO:0031346 4 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
regulation of nuclear division GO:0051783 115 0.011
positive regulation of cell migration GO:0030335 3 0.011
single organism transport GO:0044765 447 0.011
transcription dna templated GO:0006351 168 0.011
neurological system process GO:0050877 53 0.011
tissue development GO:0009888 112 0.011
gastrulation GO:0007369 58 0.011
single organism behavior GO:0044708 83 0.011
adult locomotory behavior GO:0008344 1 0.011
pigmentation GO:0043473 2 0.011
positive regulation of nucleic acid templated transcription GO:1903508 102 0.011
amine metabolic process GO:0009308 15 0.011
regulation of signal transduction GO:0009966 135 0.011
cellular response to inorganic substance GO:0071241 3 0.011
positive regulation of transcription dna templated GO:0045893 102 0.011
regulation of jun kinase activity GO:0043506 3 0.011
spindle organization GO:0007051 92 0.011
neuron projection guidance GO:0097485 82 0.011
cell surface receptor signaling pathway GO:0007166 149 0.011
axon guidance GO:0007411 82 0.010
positive regulation of protein transport GO:0051222 4 0.010
axonal fasciculation GO:0007413 79 0.010
canonical wnt signaling pathway GO:0060070 3 0.010
protein localization GO:0008104 205 0.010
bmp signaling pathway GO:0030509 3 0.010
regulation of rna biosynthetic process GO:2001141 165 0.010
establishment of organelle localization GO:0051656 123 0.010
regulation of response to wounding GO:1903034 1 0.010
epithelial tube morphogenesis GO:0060562 1 0.010
mitotic spindle organization GO:0007052 81 0.010
engulfment of apoptotic cell GO:0043652 94 0.010
neuron differentiation GO:0030182 217 0.010
cellular nitrogen compound catabolic process GO:0044270 119 0.010

klf-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.010