Caenorhabditis elegans

53 known processes

mdf-1 (CELE_C50F4.11)

Protein MDF-1

mdf-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hermaphrodite genitalia development GO:0040035 734 0.655
embryo development GO:0009790 3052 0.588
developmental process involved in reproduction GO:0003006 1165 0.511
regulation of gene expression GO:0010468 366 0.509
sex differentiation GO:0007548 909 0.407
negative regulation of biological process GO:0048519 567 0.371
organ development GO:0048513 1102 0.348
organelle organization GO:0006996 783 0.345
establishment of localization GO:0051234 1171 0.335
gamete generation GO:0007276 461 0.326
embryo development ending in birth or egg hatching GO:0009792 2992 0.306
transport GO:0006810 1093 0.253
regulation of cellular metabolic process GO:0031323 305 0.225
regulation of primary metabolic process GO:0080090 292 0.221
germ cell development GO:0007281 351 0.217
single organism reproductive process GO:0044702 1196 0.215
gene expression GO:0010467 412 0.196
reproductive system development GO:0061458 850 0.195
single organism organelle organization GO:1902589 501 0.190
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.183
cell division GO:0051301 262 0.166
localization of cell GO:0051674 313 0.165
cell morphogenesis GO:0000902 163 0.158
endocytosis GO:0006897 819 0.149
protein metabolic process GO:0019538 422 0.148
regulation of macromolecule metabolic process GO:0060255 421 0.146
protein modification process GO:0036211 207 0.138
multicellular organismal reproductive process GO:0048609 815 0.137
cell motility GO:0048870 313 0.134
cell cycle process GO:0022402 482 0.131
cell migration GO:0016477 306 0.130
negative regulation of macromolecule metabolic process GO:0010605 229 0.123
reproductive structure development GO:0048608 850 0.123
cellular localization GO:0051641 360 0.119
cytoskeleton organization GO:0007010 339 0.118
organic cyclic compound biosynthetic process GO:1901362 195 0.109
biosynthetic process GO:0009058 323 0.102
regulation of signaling GO:0023051 172 0.102
development of primary sexual characteristics GO:0045137 840 0.102
receptor mediated endocytosis GO:0006898 715 0.101
sexual reproduction GO:0019953 546 0.099
negative regulation of vulval development GO:0040027 206 0.097
regulation of cell cycle GO:0051726 194 0.097
locomotion GO:0040011 1634 0.097
positive regulation of cellular process GO:0048522 332 0.095
regulation of meiotic cell cycle GO:0051445 136 0.094
rna metabolic process GO:0016070 228 0.093
catabolic process GO:0009056 318 0.092
cell death GO:0008219 547 0.090
microtubule based process GO:0007017 182 0.090
protein complex subunit organization GO:0071822 280 0.088
protein localization GO:0008104 205 0.088
female gamete generation GO:0007292 254 0.086
death GO:0016265 547 0.085
organic substance catabolic process GO:1901575 294 0.085
regulation of cell division GO:0051302 142 0.084
oogenesis GO:0048477 229 0.081
regulation of vulval development GO:0040028 248 0.081
regulation of macromolecule biosynthetic process GO:0010556 189 0.081
negative regulation of metabolic process GO:0009892 240 0.079
cellular protein modification process GO:0006464 207 0.078
multicellular organism reproduction GO:0032504 819 0.077
cellular component movement GO:0006928 388 0.077
signaling GO:0023052 401 0.075
positive regulation of vulval development GO:0040026 52 0.075
regulation of cellular biosynthetic process GO:0031326 189 0.074
regulation of gene expression epigenetic GO:0040029 163 0.073
vesicle mediated transport GO:0016192 852 0.073
cellular biosynthetic process GO:0044249 315 0.072
genitalia development GO:0048806 741 0.072
vulval development GO:0040025 333 0.071
regulation of multicellular organism growth GO:0040014 373 0.071
regulation of multicellular organismal development GO:2000026 317 0.070
cellular protein metabolic process GO:0044267 279 0.070
meiotic nuclear division GO:0007126 300 0.070
regulation of multicellular organismal process GO:0051239 726 0.069
positive regulation of developmental growth GO:0048639 354 0.069
macromolecule localization GO:0033036 771 0.069
apoptotic process GO:0006915 478 0.068
transcription from rna polymerase ii promoter GO:0006366 149 0.068
oviposition GO:0018991 364 0.067
cell development GO:0048468 696 0.067
negative regulation of developmental process GO:0051093 227 0.067
cellular component morphogenesis GO:0032989 318 0.065
regulation of cellular component organization GO:0051128 248 0.065
single fertilization GO:0007338 61 0.062
body morphogenesis GO:0010171 620 0.062
cellular nitrogen compound biosynthetic process GO:0044271 192 0.061
programmed cell death GO:0012501 500 0.061
regulation of biological quality GO:0065008 741 0.060
regulation of metabolic process GO:0019222 478 0.059
regulation of developmental process GO:0050793 684 0.058
regulation of biosynthetic process GO:0009889 189 0.058
macromolecule modification GO:0043412 218 0.057
establishment of organelle localization GO:0051656 123 0.057
heterocycle biosynthetic process GO:0018130 187 0.057
growth GO:0040007 562 0.057
regulation of cell communication GO:0010646 176 0.057
gonad development GO:0008406 840 0.056
neuron differentiation GO:0030182 217 0.054
maintenance of location GO:0051235 580 0.053
cell cycle GO:0007049 526 0.052
nucleobase containing compound metabolic process GO:0006139 406 0.052
regulation of rna biosynthetic process GO:2001141 165 0.052
meiotic cell cycle process GO:1903046 170 0.050
multi organism reproductive process GO:0044703 867 0.049
behavior GO:0007610 527 0.049
lipid storage GO:0019915 565 0.049
organelle fission GO:0048285 363 0.049
protein catabolic process GO:0030163 162 0.048
macromolecular complex subunit organization GO:0043933 320 0.048
macromolecule catabolic process GO:0009057 202 0.047
post embryonic development GO:0009791 2152 0.047
multicellular organism growth GO:0035264 385 0.046
ribonucleoprotein complex assembly GO:0022618 4 0.046
developmental growth GO:0048589 412 0.046
cell part morphogenesis GO:0032990 152 0.046
nucleic acid templated transcription GO:0097659 169 0.045
modification dependent protein catabolic process GO:0019941 32 0.045
protein modification by small protein conjugation or removal GO:0070647 40 0.044
nervous system development GO:0007399 253 0.043
negative regulation of gene expression GO:0010629 217 0.043
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.043
cellular protein complex localization GO:0034629 3 0.043
regulation of cell morphogenesis GO:0022604 40 0.041
regulation of response to stimulus GO:0048583 243 0.041
regulation of nematode larval development GO:0061062 260 0.041
inductive cell migration GO:0040039 145 0.041
negative regulation of nematode larval development GO:0061064 208 0.041
positive regulation of neurogenesis GO:0050769 4 0.040
positive regulation of growth GO:0045927 369 0.040
single organism catabolic process GO:0044712 129 0.040
positive regulation of multicellular organismal process GO:0051240 417 0.039
aging GO:0007568 812 0.039
axon development GO:0061564 163 0.039
phagocytosis GO:0006909 115 0.039
establishment of localization in cell GO:0051649 318 0.038
rna interference GO:0016246 137 0.038
localization within membrane GO:0051668 2 0.038
lipid localization GO:0010876 573 0.038
negative regulation of multicellular organismal process GO:0051241 236 0.037
response to chemical GO:0042221 356 0.037
regulation of protein metabolic process GO:0051246 81 0.037
multicellular organismal aging GO:0010259 812 0.037
regulation of organelle organization GO:0033043 164 0.036
cytokinesis GO:0000910 80 0.036
negative regulation of cellular process GO:0048523 239 0.036
organic substance biosynthetic process GO:1901576 323 0.036
cellular macromolecular complex assembly GO:0034622 184 0.035
meiotic cell cycle GO:0051321 335 0.035
negative regulation of cell communication GO:0010648 61 0.035
neuron projection development GO:0031175 187 0.035
regulation of signal transduction GO:0009966 135 0.034
aromatic compound biosynthetic process GO:0019438 192 0.034
cellular component biogenesis GO:0044085 297 0.033
head development GO:0060322 1 0.033
regulation of growth GO:0040008 409 0.033
post embryonic organ development GO:0048569 336 0.033
positive regulation of developmental process GO:0051094 408 0.033
small molecule metabolic process GO:0044281 186 0.033
posttranscriptional regulation of gene expression GO:0010608 166 0.032
mitotic cell cycle process GO:1903047 194 0.032
translation GO:0006412 37 0.031
positive regulation of nematode larval development GO:0061063 54 0.031
positive regulation of multicellular organism growth GO:0040018 352 0.030
protein complex biogenesis GO:0070271 186 0.030
organelle localization GO:0051640 127 0.030
neurogenesis GO:0022008 236 0.030
establishment of protein localization to membrane GO:0090150 3 0.030
rna biosynthetic process GO:0032774 169 0.029
gene silencing by rna GO:0031047 143 0.029
regulation of post embryonic development GO:0048580 260 0.029
cell projection organization GO:0030030 231 0.029
organelle assembly GO:0070925 214 0.029
macromolecular complex assembly GO:0065003 193 0.029
negative regulation of response to stimulus GO:0048585 73 0.027
positive regulation of cellular metabolic process GO:0031325 178 0.027
regulation of rna metabolic process GO:0051252 173 0.027
cell proliferation GO:0008283 116 0.027
positive regulation of post embryonic development GO:0048582 54 0.026
multi multicellular organism process GO:0044706 390 0.026
striated muscle cell differentiation GO:0051146 158 0.026
regulation of translation GO:0006417 19 0.026
determination of adult lifespan GO:0008340 812 0.025
response to external stimulus GO:0009605 289 0.025
anatomical structure formation involved in morphogenesis GO:0048646 250 0.025
cellular component assembly GO:0022607 293 0.025
macromolecule biosynthetic process GO:0009059 250 0.025
chemotaxis GO:0006935 120 0.024
regulation of transcription dna templated GO:0006355 164 0.024
regulation of nuclear division GO:0051783 115 0.024
organophosphate metabolic process GO:0019637 125 0.024
apoptotic cell clearance GO:0043277 111 0.024
single organism localization GO:1902578 518 0.024
cellular macromolecule biosynthetic process GO:0034645 247 0.024
posttranscriptional gene silencing GO:0016441 143 0.023
single organism transport GO:0044765 447 0.023
single organism membrane fusion GO:0044801 13 0.023
posttranscriptional gene silencing by rna GO:0035194 143 0.023
centrosomal and pronuclear rotation GO:0035047 6 0.023
immune response GO:0006955 192 0.022
single organism signaling GO:0044700 401 0.022
negative regulation of signaling GO:0023057 61 0.022
microtubule polymerization or depolymerization GO:0031109 22 0.022
muscle tissue development GO:0060537 1 0.022
signal transduction GO:0007165 317 0.022
organonitrogen compound metabolic process GO:1901564 151 0.022
muscle cell development GO:0055001 158 0.022
cell type specific apoptotic process GO:0097285 4 0.021
regulation of meiosis GO:0040020 94 0.021
positive regulation of cell cycle GO:0045787 55 0.020
cell projection morphogenesis GO:0048858 148 0.020
regulation of intracellular signal transduction GO:1902531 77 0.020
negative regulation of post embryonic development GO:0048581 208 0.020
multicellular organismal reproductive behavior GO:0033057 384 0.020
regulation of anatomical structure morphogenesis GO:0022603 51 0.020
proteolysis GO:0006508 61 0.019
negative regulation of signal transduction GO:0009968 60 0.019
cellular nitrogen compound catabolic process GO:0044270 119 0.019
cell surface receptor signaling pathway GO:0007166 149 0.019
spindle organization GO:0007051 92 0.019
heterocycle catabolic process GO:0046700 119 0.019
regulation of cellular protein metabolic process GO:0032268 75 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.019
intracellular signal transduction GO:0035556 96 0.019
membrane organization GO:0061024 135 0.019
actin cytoskeleton organization GO:0030036 184 0.019
cellular macromolecule localization GO:0070727 75 0.019
regulation of cell cycle process GO:0010564 145 0.018
membrane invagination GO:0010324 98 0.018
generation of neurons GO:0048699 235 0.018
purine nucleoside metabolic process GO:0042278 92 0.018
multi organism reproductive behavior GO:0044705 387 0.018
regulation of cytoskeleton organization GO:0051493 41 0.018
positive regulation of gene expression GO:0010628 112 0.018
fertilization GO:0009566 63 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.018
canonical wnt signaling pathway GO:0060070 3 0.017
multi organism behavior GO:0051705 389 0.017
mitotic spindle organization GO:0007052 81 0.017
oocyte axis specification GO:0007309 2 0.017
dna templated transcription elongation GO:0006354 1 0.017
regulation of nucleic acid templated transcription GO:1903506 165 0.017
nucleic acid metabolic process GO:0090304 299 0.017
carboxylic acid metabolic process GO:0019752 34 0.017
oocyte construction GO:0007308 2 0.017
positive regulation of intracellular transport GO:0032388 2 0.017
spermatogenesis GO:0007283 41 0.017
positive regulation of biosynthetic process GO:0009891 109 0.017
regulation of cellular component movement GO:0051270 62 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.017
muscle structure development GO:0061061 191 0.016
positive regulation of meiotic cell cycle GO:0051446 47 0.016
muscle cell differentiation GO:0042692 171 0.016
cellular response to dna damage stimulus GO:0006974 41 0.016
sleep GO:0030431 4 0.016
positive regulation of rna biosynthetic process GO:1902680 102 0.016
cellular protein localization GO:0034613 75 0.015
nuclear pore distribution GO:0031081 2 0.015
regulation of cell projection assembly GO:0060491 3 0.015
nucleobase containing compound biosynthetic process GO:0034654 184 0.015
regulation of molecular function GO:0065009 89 0.015
pigmentation GO:0043473 2 0.015
organic cyclic compound catabolic process GO:1901361 119 0.015
reproductive behavior GO:0019098 387 0.015
taxis GO:0042330 128 0.015
regulation of catalytic activity GO:0050790 78 0.015
regulation of developmental growth GO:0048638 389 0.015
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.014
cellular component assembly involved in morphogenesis GO:0010927 183 0.014
cellular protein complex assembly GO:0043623 178 0.014
myosin filament organization GO:0031033 138 0.014
phosphate containing compound metabolic process GO:0006796 232 0.014
regulation of apoptotic process GO:0042981 36 0.014
negative regulation of neurogenesis GO:0050768 4 0.014
positive regulation of chromosome segregation GO:0051984 1 0.014
regeneration GO:0031099 4 0.014
histone modification GO:0016570 30 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.014
cellular macromolecule catabolic process GO:0044265 73 0.014
negative regulation of cellular metabolic process GO:0031324 95 0.014
cellular catabolic process GO:0044248 199 0.014
cell cycle g1 s phase transition GO:0044843 2 0.013
protein neddylation GO:0045116 3 0.013
guanosine containing compound catabolic process GO:1901069 48 0.013
nucleus organization GO:0006997 38 0.013
modification of morphology or physiology of other organism GO:0035821 2 0.013
phosphorus metabolic process GO:0006793 232 0.013
positive regulation of chromosome organization GO:2001252 2 0.013
protein complex assembly GO:0006461 186 0.013
sex determination GO:0007530 60 0.012
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.012
g1 s transition of mitotic cell cycle GO:0000082 2 0.012
male gamete generation GO:0048232 41 0.012
establishment or maintenance of cell polarity GO:0007163 63 0.012
phagocytosis engulfment GO:0006911 98 0.012
transmembrane transport GO:0055085 110 0.012
organic substance transport GO:0071702 113 0.012
actin cytoskeleton reorganization GO:0031532 4 0.012
myosin filament assembly GO:0031034 138 0.012
single organism biosynthetic process GO:0044711 91 0.012
regulation of localization GO:0032879 194 0.012
nucleobase containing compound catabolic process GO:0034655 114 0.012
regulation of cell proliferation GO:0042127 105 0.012
nucleoside catabolic process GO:0009164 78 0.011
cell maturation GO:0048469 26 0.011
intracellular receptor signaling pathway GO:0030522 2 0.011
ribonucleotide metabolic process GO:0009259 99 0.011
positive regulation of cellular component organization GO:0051130 34 0.011
response to other organism GO:0051707 101 0.011
protein complex localization GO:0031503 3 0.011
regulation of locomotion GO:0040012 161 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
hermaphrodite germ line sex determination GO:0040021 48 0.011
protein oligomerization GO:0051259 4 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
neuron development GO:0048666 199 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.011
positive regulation of intracellular protein transport GO:0090316 2 0.011
protein localization to membrane GO:0072657 11 0.011
regulation of cell differentiation GO:0045595 81 0.011
cellular amine metabolic process GO:0044106 15 0.011
striated muscle cell development GO:0055002 157 0.011
positive regulation of protein transport GO:0051222 4 0.010
rna transport GO:0050658 3 0.010
mitotic nuclear division GO:0007067 89 0.010
dendrite development GO:0016358 42 0.010
rna processing GO:0006396 34 0.010
nucleic acid transport GO:0050657 3 0.010
negative regulation of cellular protein metabolic process GO:0032269 27 0.010
pronuclear migration GO:0035046 51 0.010
cellular protein catabolic process GO:0044257 37 0.010
cellular response to chemical stimulus GO:0070887 129 0.010
purine nucleotide metabolic process GO:0006163 95 0.010

mdf-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
congenital hypoplastic anemia DOID:1342 0 0.018
immune system disease DOID:2914 0 0.018
diamond blackfan anemia DOID:1339 0 0.018
aplastic anemia DOID:12449 0 0.018
disease of anatomical entity DOID:7 0 0.018
bone marrow disease DOID:4961 0 0.018
anemia DOID:2355 0 0.018
hematopoietic system disease DOID:74 0 0.018
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011