Caenorhabditis elegans

132 known processes

sys-1 (CELE_T23D8.9)

Protein SYS-1

sys-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic organ development GO:0048569 336 0.693
post embryonic development GO:0009791 2152 0.576
embryo development ending in birth or egg hatching GO:0009792 2992 0.525
cell fate commitment GO:0045165 139 0.492
developmental process involved in reproduction GO:0003006 1165 0.428
multicellular organism reproduction GO:0032504 819 0.289
embryo development GO:0009790 3052 0.285
death GO:0016265 547 0.279
sexual reproduction GO:0019953 546 0.261
specification of axis polarity GO:0065001 13 0.257
vulval development GO:0040025 333 0.231
single organism organelle organization GO:1902589 501 0.209
hermaphrodite genitalia development GO:0040035 734 0.202
multicellular organismal reproductive process GO:0048609 815 0.199
body morphogenesis GO:0010171 620 0.194
cell death GO:0008219 547 0.190
regulation of vulval development GO:0040028 248 0.189
cellular localization GO:0051641 360 0.186
organelle organization GO:0006996 783 0.185
regulation of biological quality GO:0065008 741 0.183
regulation of developmental process GO:0050793 684 0.179
chemotaxis GO:0006935 120 0.178
programmed cell death GO:0012501 500 0.177
macromolecule localization GO:0033036 771 0.175
protein complex subunit organization GO:0071822 280 0.173
response to external stimulus GO:0009605 289 0.171
proximal distal pattern formation GO:0009954 6 0.169
sex differentiation GO:0007548 909 0.169
positive regulation of multicellular organismal process GO:0051240 417 0.166
positive regulation of signaling GO:0023056 66 0.156
gonad development GO:0008406 840 0.156
establishment of localization GO:0051234 1171 0.152
taxis GO:0042330 128 0.150
organic cyclic compound biosynthetic process GO:1901362 195 0.146
immune response GO:0006955 192 0.143
organ development GO:0048513 1102 0.142
female gamete generation GO:0007292 254 0.140
regulation of macromolecule biosynthetic process GO:0010556 189 0.128
gamete generation GO:0007276 461 0.126
oviposition GO:0018991 364 0.121
apoptotic process GO:0006915 478 0.119
establishment of localization in cell GO:0051649 318 0.114
regulation of post embryonic development GO:0048580 260 0.113
cell cycle GO:0007049 526 0.111
genitalia development GO:0048806 741 0.110
tissue development GO:0009888 112 0.107
locomotion GO:0040011 1634 0.106
regulation of nematode larval development GO:0061062 260 0.104
digestive tract morphogenesis GO:0048546 76 0.102
response to chemical GO:0042221 356 0.102
oogenesis GO:0048477 229 0.102
regulation of macromolecule metabolic process GO:0060255 421 0.100
protein localization GO:0008104 205 0.098
reproductive system development GO:0061458 850 0.096
anatomical structure formation involved in morphogenesis GO:0048646 250 0.094
negative regulation of vulval development GO:0040027 206 0.093
transcription dna templated GO:0006351 168 0.092
regulation of rna biosynthetic process GO:2001141 165 0.092
axonogenesis GO:0007409 102 0.090
axon development GO:0061564 163 0.089
maintenance of location GO:0051235 580 0.085
single organism reproductive process GO:0044702 1196 0.083
endocytosis GO:0006897 819 0.080
lipid localization GO:0010876 573 0.079
cell division GO:0051301 262 0.078
negative regulation of multicellular organismal process GO:0051241 236 0.078
chromatin organization GO:0006325 32 0.077
phosphorylation GO:0016310 116 0.077
multicellular organismal reproductive behavior GO:0033057 384 0.077
gene expression GO:0010467 412 0.077
regulation of gene expression epigenetic GO:0040029 163 0.076
polarity specification of proximal distal axis GO:0010085 6 0.075
protein metabolic process GO:0019538 422 0.074
neuron projection development GO:0031175 187 0.074
regulation of cell fate specification GO:0042659 22 0.074
meiotic cell cycle GO:0051321 335 0.072
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.072
vesicle mediated transport GO:0016192 852 0.071
positive regulation of gene expression GO:0010628 112 0.069
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.068
striated muscle cell differentiation GO:0051146 158 0.067
regulation of primary metabolic process GO:0080090 292 0.067
gastrulation GO:0007369 58 0.066
regulation of multicellular organismal process GO:0051239 726 0.066
lipid storage GO:0019915 565 0.066
regulation of cellular metabolic process GO:0031323 305 0.066
multi organism reproductive behavior GO:0044705 387 0.064
macromolecular complex subunit organization GO:0043933 320 0.064
regulation of multicellular organismal development GO:2000026 317 0.064
positive regulation of multicellular organism growth GO:0040018 352 0.064
multi organism behavior GO:0051705 389 0.062
negative regulation of post embryonic development GO:0048581 208 0.061
organelle assembly GO:0070925 214 0.061
development of primary sexual characteristics GO:0045137 840 0.060
epithelium development GO:0060429 68 0.060
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.059
negative regulation of biological process GO:0048519 567 0.059
multi organism reproductive process GO:0044703 867 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.057
cell development GO:0048468 696 0.057
macromolecule modification GO:0043412 218 0.056
negative regulation of developmental process GO:0051093 227 0.055
cell cycle process GO:0022402 482 0.055
gene silencing by rna GO:0031047 143 0.054
regulation of neurogenesis GO:0050767 40 0.054
germ cell development GO:0007281 351 0.054
posttranscriptional regulation of gene expression GO:0010608 166 0.053
positive regulation of signal transduction GO:0009967 40 0.052
cellular component biogenesis GO:0044085 297 0.051
canonical wnt signaling pathway GO:0060070 3 0.051
cytoskeleton organization GO:0007010 339 0.051
regulation of cell cycle GO:0051726 194 0.051
meiotic chromosome segregation GO:0045132 139 0.050
phosphate containing compound metabolic process GO:0006796 232 0.050
cellular biosynthetic process GO:0044249 315 0.050
asymmetric cell division GO:0008356 36 0.049
cellular nitrogen compound catabolic process GO:0044270 119 0.049
cellular component assembly GO:0022607 293 0.049
muscle structure development GO:0061061 191 0.049
multi multicellular organism process GO:0044706 390 0.048
secretion by cell GO:0032940 138 0.048
positive regulation of developmental growth GO:0048639 354 0.047
mitotic cell cycle process GO:1903047 194 0.047
secretion GO:0046903 147 0.046
muscle cell differentiation GO:0042692 171 0.046
sensory organ morphogenesis GO:0090596 2 0.046
posttranscriptional gene silencing GO:0016441 143 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.045
nucleobase containing compound metabolic process GO:0006139 406 0.044
receptor mediated endocytosis GO:0006898 715 0.044
cell cell signaling GO:0007267 118 0.043
regulation of locomotion GO:0040012 161 0.043
neuroblast proliferation GO:0007405 9 0.043
axon guidance GO:0007411 82 0.042
positive regulation of intracellular transport GO:0032388 2 0.041
biosynthetic process GO:0009058 323 0.041
negative regulation of nematode larval development GO:0061064 208 0.040
determination of adult lifespan GO:0008340 812 0.040
cell surface receptor signaling pathway GO:0007166 149 0.040
positive regulation of developmental process GO:0051094 408 0.039
neuron differentiation GO:0030182 217 0.039
cellular component movement GO:0006928 388 0.039
meiotic cell cycle process GO:1903046 170 0.039
regulation of nitrogen compound metabolic process GO:0051171 222 0.037
positive regulation of transcription dna templated GO:0045893 102 0.037
positive regulation of growth GO:0045927 369 0.037
positive regulation of cellular biosynthetic process GO:0031328 109 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.037
reproductive behavior GO:0019098 387 0.037
membrane organization GO:0061024 135 0.036
positive regulation of nucleic acid templated transcription GO:1903508 102 0.036
phosphorus metabolic process GO:0006793 232 0.036
positive regulation of intracellular signal transduction GO:1902533 24 0.035
regulation of metabolic process GO:0019222 478 0.035
signaling GO:0023052 401 0.035
negative regulation of cellular process GO:0048523 239 0.035
regulation of cell communication GO:0010646 176 0.035
cell morphogenesis GO:0000902 163 0.033
dna metabolic process GO:0006259 74 0.033
rna biosynthetic process GO:0032774 169 0.033
meiotic nuclear division GO:0007126 300 0.033
positive regulation of embryonic development GO:0040019 3 0.033
regulation of developmental growth GO:0048638 389 0.032
posttranscriptional gene silencing by rna GO:0035194 143 0.032
macromolecular complex assembly GO:0065003 193 0.032
negative regulation of metabolic process GO:0009892 240 0.032
system process GO:0003008 136 0.032
tissue morphogenesis GO:0048729 65 0.032
multicellular organism growth GO:0035264 385 0.031
multicellular organismal aging GO:0010259 812 0.031
positive regulation of neurogenesis GO:0050769 4 0.031
positive regulation of protein transport GO:0051222 4 0.031
regulation of cell fate commitment GO:0010453 22 0.030
regulation of molecular function GO:0065009 89 0.030
positive regulation of epithelial cell proliferation GO:0050679 1 0.030
behavior GO:0007610 527 0.030
single organism localization GO:1902578 518 0.029
cellular catabolic process GO:0044248 199 0.029
head development GO:0060322 1 0.029
intracellular transport GO:0046907 77 0.029
nucleic acid metabolic process GO:0090304 299 0.028
growth GO:0040007 562 0.028
organ morphogenesis GO:0009887 67 0.028
intracellular receptor signaling pathway GO:0030522 2 0.028
molting cycle GO:0042303 281 0.027
cellular macromolecule localization GO:0070727 75 0.026
single organism transport GO:0044765 447 0.026
embryonic morphogenesis GO:0048598 152 0.026
rna interference GO:0016246 137 0.026
long term memory GO:0007616 2 0.026
positive regulation of response to stimulus GO:0048584 55 0.026
striated muscle cell development GO:0055002 157 0.026
signal transduction GO:0007165 317 0.026
regulation of cytoplasmic transport GO:1903649 3 0.026
regulation of protein localization GO:0032880 50 0.025
cytoplasmic transport GO:0016482 23 0.025
positive regulation of cellular metabolic process GO:0031325 178 0.025
protein complex assembly GO:0006461 186 0.024
gene silencing GO:0016458 143 0.024
intracellular signal transduction GO:0035556 96 0.024
regeneration GO:0031099 4 0.024
aging GO:0007568 812 0.024
inductive cell migration GO:0040039 145 0.024
carbohydrate derivative metabolic process GO:1901135 141 0.024
organic substance biosynthetic process GO:1901576 323 0.024
organic substance transport GO:0071702 113 0.024
chromosome organization GO:0051276 104 0.023
macromolecule biosynthetic process GO:0009059 250 0.023
positive regulation of cellular process GO:0048522 332 0.023
protein complex biogenesis GO:0070271 186 0.023
neuron projection guidance GO:0097485 82 0.022
peptidyl amino acid modification GO:0018193 58 0.022
transport GO:0006810 1093 0.022
detection of external stimulus GO:0009581 4 0.022
developmental growth GO:0048589 412 0.022
regulation of gene expression GO:0010468 366 0.022
organelle localization GO:0051640 127 0.021
endodermal cell differentiation GO:0035987 18 0.021
regulation of epithelial cell proliferation GO:0050678 1 0.021
negative regulation of macromolecule metabolic process GO:0010605 229 0.021
response to wounding GO:0009611 4 0.021
cellular component morphogenesis GO:0032989 318 0.021
regulation of transport GO:0051049 91 0.021
reproductive structure development GO:0048608 850 0.021
regulation of embryonic development GO:0045995 16 0.021
regulation of multi organism process GO:0043900 69 0.021
regulation of reproductive process GO:2000241 66 0.021
muscle cell development GO:0055001 158 0.021
cellular protein localization GO:0034613 75 0.020
generation of neurons GO:0048699 235 0.020
internal peptidyl lysine acetylation GO:0018393 3 0.020
regulation of filopodium assembly GO:0051489 2 0.020
regulation of cellular biosynthetic process GO:0031326 189 0.020
regulation of multicellular organism growth GO:0040014 373 0.020
cellular component assembly involved in morphogenesis GO:0010927 183 0.020
cell morphogenesis involved in differentiation GO:0000904 112 0.019
response to other organism GO:0051707 101 0.019
positive regulation of phosphate metabolic process GO:0045937 56 0.019
regulation of mitotic cell cycle embryonic GO:0009794 5 0.018
regulation of stem cell differentiation GO:2000736 1 0.018
phagocytosis engulfment GO:0006911 98 0.018
single organism signaling GO:0044700 401 0.018
positive regulation of rna biosynthetic process GO:1902680 102 0.018
positive regulation of molecular function GO:0044093 61 0.018
nematode male tail tip morphogenesis GO:0045138 77 0.018
hormone metabolic process GO:0042445 3 0.018
aromatic compound biosynthetic process GO:0019438 192 0.018
regulation of nucleocytoplasmic transport GO:0046822 3 0.018
epithelial tube morphogenesis GO:0060562 1 0.018
cellular protein complex assembly GO:0043623 178 0.017
regulation of epithelial cell differentiation GO:0030856 4 0.017
regulation of neuron projection development GO:0010975 31 0.017
regulation of anatomical structure morphogenesis GO:0022603 51 0.017
cell migration GO:0016477 306 0.017
response to external biotic stimulus GO:0043207 101 0.017
phagocytosis GO:0006909 115 0.017
positive regulation of nematode larval development GO:0061063 54 0.017
organelle fission GO:0048285 363 0.017
protein phosphorylation GO:0006468 85 0.016
single organism intracellular transport GO:1902582 70 0.016
myofibril assembly GO:0030239 154 0.016
cellular nitrogen compound biosynthetic process GO:0044271 192 0.016
establishment or maintenance of cell polarity GO:0007163 63 0.016
regulation of cell development GO:0060284 49 0.016
small molecule metabolic process GO:0044281 186 0.016
male anatomical structure morphogenesis GO:0090598 78 0.015
actomyosin structure organization GO:0031032 154 0.015
regulation of rna metabolic process GO:0051252 173 0.015
regulation of signaling GO:0023051 172 0.015
cell projection organization GO:0030030 231 0.015
regulation of growth GO:0040008 409 0.015
organic acid metabolic process GO:0006082 47 0.015
aromatic compound catabolic process GO:0019439 116 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
positive regulation of intracellular protein transport GO:0090316 2 0.015
response to organic substance GO:0010033 131 0.015
oxoacid metabolic process GO:0043436 47 0.015
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.014
neural precursor cell proliferation GO:0061351 9 0.014
establishment of protein localization GO:0045184 50 0.014
organonitrogen compound metabolic process GO:1901564 151 0.014
regulation of localization GO:0032879 194 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.014
cellular protein modification process GO:0006464 207 0.014
catabolic process GO:0009056 318 0.014
peptidyl lysine acetylation GO:0018394 3 0.014
rna metabolic process GO:0016070 228 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
cellular macromolecular complex assembly GO:0034622 184 0.013
regulation of meiotic cell cycle GO:0051445 136 0.013
heterocycle catabolic process GO:0046700 119 0.013
regulation of response to stimulus GO:0048583 243 0.013
organophosphate metabolic process GO:0019637 125 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.013
wnt signaling pathway GO:0016055 27 0.013
neurological system process GO:0050877 53 0.013
mesoderm development GO:0007498 27 0.013
regulation of cell cell adhesion GO:0022407 1 0.013
myosin filament organization GO:0031033 138 0.013
epithelial cell proliferation GO:0050673 1 0.013
regulation of signal transduction GO:0009966 135 0.013
apical junction assembly GO:0043297 1 0.013
cation transport GO:0006812 78 0.013
tube formation GO:0035148 2 0.012
regulation of protein targeting GO:1903533 3 0.012
positive regulation of macromolecule metabolic process GO:0010604 149 0.012
cell projection morphogenesis GO:0048858 148 0.012
cytokinesis GO:0000910 80 0.012
positive regulation of cell cycle GO:0045787 55 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.012
histone h3 acetylation GO:0043966 1 0.012
synaptic transmission GO:0007268 106 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.012
epithelial cell morphogenesis GO:0003382 2 0.012
regulation of cell differentiation GO:0045595 81 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
innate immune response GO:0045087 190 0.012
cellular ketone metabolic process GO:0042180 14 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
internal protein amino acid acetylation GO:0006475 3 0.012
muscle tissue development GO:0060537 1 0.011
membrane invagination GO:0010324 98 0.011
transcription from rna polymerase ii promoter GO:0006366 149 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
tube morphogenesis GO:0035239 79 0.011
actin filament based process GO:0030029 191 0.011
regulation of neuron differentiation GO:0045664 40 0.011
carbohydrate derivative biosynthetic process GO:1901137 46 0.011
cytoskeleton dependent cytokinesis GO:0061640 35 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.011
regulation of mitotic cell cycle GO:0007346 76 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
hormone transport GO:0009914 2 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 1 0.011
regulation of cell motility GO:2000145 57 0.011
microtubule based process GO:0007017 182 0.011
covalent chromatin modification GO:0016569 30 0.011
engulfment of apoptotic cell GO:0043652 94 0.011
negative regulation of signaling GO:0023057 61 0.011
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 2 0.011
protein oligomerization GO:0051259 4 0.011
response to biotic stimulus GO:0009607 101 0.011
negative regulation of nucleic acid templated transcription GO:1903507 53 0.011
regulation of cellular component movement GO:0051270 62 0.011
positive regulation of biosynthetic process GO:0009891 109 0.010
positive regulation of catalytic activity GO:0043085 59 0.010
cell motility GO:0048870 313 0.010
glycoprotein metabolic process GO:0009100 29 0.010
skeletal muscle organ development GO:0060538 3 0.010
positive regulation of cell communication GO:0010647 69 0.010
positive regulation of protein metabolic process GO:0051247 45 0.010
nucleobase containing compound catabolic process GO:0034655 114 0.010
cell part morphogenesis GO:0032990 152 0.010
chromatin remodeling GO:0006338 2 0.010
nucleotide catabolic process GO:0009166 77 0.010

sys-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.021
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
disease of anatomical entity DOID:7 0 0.011