Caenorhabditis elegans

47 known processes

npp-2 (CELE_T01G9.4)

Protein NPP-2

npp-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.890
heterocycle biosynthetic process GO:0018130 187 0.846
cell cycle process GO:0022402 482 0.843
multicellular organism reproduction GO:0032504 819 0.727
positive regulation of nucleic acid templated transcription GO:1903508 102 0.703
positive regulation of biosynthetic process GO:0009891 109 0.614
regulation of nucleic acid templated transcription GO:1903506 165 0.599
organelle organization GO:0006996 783 0.561
sex differentiation GO:0007548 909 0.544
nucleic acid templated transcription GO:0097659 169 0.535
locomotion GO:0040011 1634 0.511
rna biosynthetic process GO:0032774 169 0.486
post embryonic development GO:0009791 2152 0.483
positive regulation of rna biosynthetic process GO:1902680 102 0.482
multi organism reproductive process GO:0044703 867 0.478
positive regulation of cellular biosynthetic process GO:0031328 109 0.450
regulation of transcription dna templated GO:0006355 164 0.447
establishment of localization GO:0051234 1171 0.445
multicellular organismal reproductive process GO:0048609 815 0.440
single organism reproductive process GO:0044702 1196 0.440
regulation of rna biosynthetic process GO:2001141 165 0.438
embryo development GO:0009790 3052 0.438
oviposition GO:0018991 364 0.437
positive regulation of cellular metabolic process GO:0031325 178 0.436
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.432
developmental process involved in reproduction GO:0003006 1165 0.423
nucleobase containing compound metabolic process GO:0006139 406 0.421
vesicle mediated transport GO:0016192 852 0.418
regulation of rna metabolic process GO:0051252 173 0.417
aromatic compound biosynthetic process GO:0019438 192 0.409
cellular nitrogen compound biosynthetic process GO:0044271 192 0.406
meiotic cell cycle GO:0051321 335 0.380
receptor mediated endocytosis GO:0006898 715 0.368
meiotic chromosome segregation GO:0045132 139 0.354
gene expression GO:0010467 412 0.345
post embryonic organ development GO:0048569 336 0.339
organic cyclic compound biosynthetic process GO:1901362 195 0.336
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.335
positive regulation of macromolecule metabolic process GO:0010604 149 0.333
sexual reproduction GO:0019953 546 0.323
regulation of cell cycle GO:0051726 194 0.314
germ cell development GO:0007281 351 0.297
positive regulation of transcription dna templated GO:0045893 102 0.278
positive regulation of metabolic process GO:0009893 187 0.277
regulation of vulval development GO:0040028 248 0.269
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.262
regulation of gene expression GO:0010468 366 0.256
gamete generation GO:0007276 461 0.253
regulation of primary metabolic process GO:0080090 292 0.252
multicellular organismal reproductive behavior GO:0033057 384 0.252
meiotic nuclear division GO:0007126 300 0.246
gonad development GO:0008406 840 0.244
hermaphrodite genitalia development GO:0040035 734 0.241
signaling GO:0023052 401 0.239
regulation of biosynthetic process GO:0009889 189 0.236
transcription dna templated GO:0006351 168 0.234
protein complex subunit organization GO:0071822 280 0.228
organ development GO:0048513 1102 0.228
cell division GO:0051301 262 0.228
regulation of multicellular organismal process GO:0051239 726 0.224
positive regulation of cellular process GO:0048522 332 0.224
rna metabolic process GO:0016070 228 0.221
single organism localization GO:1902578 518 0.220
single organism organelle organization GO:1902589 501 0.210
multi multicellular organism process GO:0044706 390 0.207
organic substance biosynthetic process GO:1901576 323 0.204
single organism transport GO:0044765 447 0.204
cell cycle GO:0007049 526 0.203
regulation of cellular metabolic process GO:0031323 305 0.202
cellular macromolecule biosynthetic process GO:0034645 247 0.201
endocytosis GO:0006897 819 0.198
transcription from rna polymerase ii promoter GO:0006366 149 0.198
positive regulation of rna metabolic process GO:0051254 103 0.195
catabolic process GO:0009056 318 0.192
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.192
cellular biosynthetic process GO:0044249 315 0.191
cell migration GO:0016477 306 0.188
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.188
nucleic acid metabolic process GO:0090304 299 0.186
single organism signaling GO:0044700 401 0.185
positive regulation of gene expression GO:0010628 112 0.182
multi organism reproductive behavior GO:0044705 387 0.181
macromolecular complex subunit organization GO:0043933 320 0.172
genitalia development GO:0048806 741 0.171
cell development GO:0048468 696 0.170
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.163
chromatin modification GO:0016568 32 0.163
growth GO:0040007 562 0.160
regulation of nitrogen compound metabolic process GO:0051171 222 0.159
cell motility GO:0048870 313 0.159
programmed cell death GO:0012501 500 0.155
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.153
multicellular organismal aging GO:0010259 812 0.147
regulation of multicellular organismal development GO:2000026 317 0.145
regulation of nematode larval development GO:0061062 260 0.143
reproductive structure development GO:0048608 850 0.143
vulval development GO:0040025 333 0.143
regulation of mitotic cell cycle GO:0007346 76 0.141
regulation of macromolecule biosynthetic process GO:0010556 189 0.140
biosynthetic process GO:0009058 323 0.137
localization of cell GO:0051674 313 0.134
regulation of cell cycle process GO:0010564 145 0.133
reproductive system development GO:0061458 850 0.133
multi organism behavior GO:0051705 389 0.131
regulation of developmental process GO:0050793 684 0.130
nucleobase containing compound biosynthetic process GO:0034654 184 0.128
molting cycle GO:0042303 281 0.126
organelle fission GO:0048285 363 0.125
regulation of nuclear division GO:0051783 115 0.123
oogenesis GO:0048477 229 0.122
body morphogenesis GO:0010171 620 0.121
regulation of signaling GO:0023051 172 0.120
regulation of chromosome organization GO:0033044 20 0.118
transport GO:0006810 1093 0.118
aging GO:0007568 812 0.116
regulation of cell division GO:0051302 142 0.112
regulation of post embryonic development GO:0048580 260 0.112
microtubule based process GO:0007017 182 0.108
development of primary sexual characteristics GO:0045137 840 0.108
cellular component assembly GO:0022607 293 0.105
regulation of cellular biosynthetic process GO:0031326 189 0.104
chromosome organization GO:0051276 104 0.104
meiotic cell cycle process GO:1903046 170 0.104
regulation of cellular component organization GO:0051128 248 0.104
female gamete generation GO:0007292 254 0.099
chromosome segregation GO:0007059 180 0.098
macromolecule localization GO:0033036 771 0.095
protein metabolic process GO:0019538 422 0.094
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.094
signal transduction GO:0007165 317 0.094
regulation of metabolic process GO:0019222 478 0.093
cell part morphogenesis GO:0032990 152 0.091
inductive cell migration GO:0040039 145 0.089
organonitrogen compound metabolic process GO:1901564 151 0.089
small molecule metabolic process GO:0044281 186 0.088
determination of adult lifespan GO:0008340 812 0.088
rna processing GO:0006396 34 0.085
regulation of meiosis GO:0040020 94 0.083
regulation of cellular protein metabolic process GO:0032268 75 0.081
cell death GO:0008219 547 0.077
negative regulation of biological process GO:0048519 567 0.076
cellular protein modification process GO:0006464 207 0.074
negative regulation of gene expression GO:0010629 217 0.073
single organism catabolic process GO:0044712 129 0.072
neurogenesis GO:0022008 236 0.071
behavior GO:0007610 527 0.069
negative regulation of transcription dna templated GO:0045892 53 0.068
rrna metabolic process GO:0016072 3 0.066
negative regulation of nucleic acid templated transcription GO:1903507 53 0.066
negative regulation of cellular process GO:0048523 239 0.065
regulation of cell communication GO:0010646 176 0.065
maintenance of location GO:0051235 580 0.063
posttranscriptional gene silencing GO:0016441 143 0.063
apoptotic process GO:0006915 478 0.063
cell projection morphogenesis GO:0048858 148 0.063
nucleobase containing small molecule metabolic process GO:0055086 115 0.062
glycosyl compound metabolic process GO:1901657 100 0.062
dna metabolic process GO:0006259 74 0.060
ribonucleoside metabolic process GO:0009119 98 0.059
chromatin remodeling GO:0006338 2 0.058
multicellular organism growth GO:0035264 385 0.057
mrna metabolic process GO:0016071 31 0.057
gene silencing GO:0016458 143 0.056
organic substance catabolic process GO:1901575 294 0.056
regulation of signal transduction GO:0009966 135 0.055
cellular component movement GO:0006928 388 0.055
purine nucleoside metabolic process GO:0042278 92 0.054
regulation of mitosis GO:0007088 18 0.054
phosphorus metabolic process GO:0006793 232 0.053
positive regulation of developmental process GO:0051094 408 0.052
intracellular receptor signaling pathway GO:0030522 2 0.052
regulation of organelle organization GO:0033043 164 0.052
negative regulation of rna biosynthetic process GO:1902679 53 0.051
lipid storage GO:0019915 565 0.051
lipid localization GO:0010876 573 0.051
regulation of biological quality GO:0065008 741 0.050
chromatin organization GO:0006325 32 0.048
purine nucleotide metabolic process GO:0006163 95 0.048
regulation of gene expression epigenetic GO:0040029 163 0.047
regulation of macromolecule metabolic process GO:0060255 421 0.047
head development GO:0060322 1 0.046
reproductive behavior GO:0019098 387 0.046
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.046
mitotic spindle organization GO:0007052 81 0.046
purine ribonucleoside metabolic process GO:0046128 92 0.046
cell cell signaling GO:0007267 118 0.046
ribonucleotide catabolic process GO:0009261 75 0.046
regulation of molecular function GO:0065009 89 0.045
atp metabolic process GO:0046034 42 0.045
mitotic cell cycle process GO:1903047 194 0.045
nucleoside phosphate metabolic process GO:0006753 108 0.045
rna localization GO:0006403 3 0.044
phosphate containing compound metabolic process GO:0006796 232 0.044
nucleus organization GO:0006997 38 0.043
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.041
cellular nitrogen compound catabolic process GO:0044270 119 0.041
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.041
protein complex assembly GO:0006461 186 0.041
regulation of localization GO:0032879 194 0.041
gene silencing by rna GO:0031047 143 0.040
regulation of growth GO:0040008 409 0.040
developmental growth GO:0048589 412 0.040
purine ribonucleotide metabolic process GO:0009150 95 0.040
negative regulation of biosynthetic process GO:0009890 65 0.040
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.039
posttranscriptional gene silencing by rna GO:0035194 143 0.039
cytoskeleton organization GO:0007010 339 0.039
phagocytosis GO:0006909 115 0.038
negative regulation of metabolic process GO:0009892 240 0.038
negative regulation of macromolecule metabolic process GO:0010605 229 0.038
nucleoside monophosphate metabolic process GO:0009123 46 0.036
positive regulation of cell communication GO:0010647 69 0.036
regulation of meiotic cell cycle GO:0051445 136 0.036
positive regulation of multicellular organism growth GO:0040018 352 0.036
sensory organ morphogenesis GO:0090596 2 0.035
death GO:0016265 547 0.035
aromatic compound catabolic process GO:0019439 116 0.035
nuclear pore organization GO:0006999 2 0.035
regulation of nucleocytoplasmic transport GO:0046822 3 0.035
cellular response to organic substance GO:0071310 119 0.035
macromolecule biosynthetic process GO:0009059 250 0.035
intracellular signal transduction GO:0035556 96 0.034
nucleoside triphosphate metabolic process GO:0009141 87 0.034
purine nucleoside catabolic process GO:0006152 75 0.034
nucleoside triphosphate catabolic process GO:0009143 72 0.033
neuron development GO:0048666 199 0.033
cellular macromolecular complex assembly GO:0034622 184 0.033
organic acid metabolic process GO:0006082 47 0.033
ribonucleotide metabolic process GO:0009259 99 0.033
rna interference GO:0016246 137 0.033
positive regulation of multicellular organismal process GO:0051240 417 0.033
purine nucleotide catabolic process GO:0006195 75 0.033
cellular component biogenesis GO:0044085 297 0.032
cellular response to stress GO:0033554 162 0.032
positive regulation of vulval development GO:0040026 52 0.032
cellular response to chemical stimulus GO:0070887 129 0.032
organelle assembly GO:0070925 214 0.032
response to chemical GO:0042221 356 0.031
carbohydrate derivative catabolic process GO:1901136 82 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.031
purine ribonucleoside catabolic process GO:0046130 75 0.031
heterocycle catabolic process GO:0046700 119 0.030
regulation of developmental growth GO:0048638 389 0.030
macromolecule modification GO:0043412 218 0.029
phagocytosis engulfment GO:0006911 98 0.029
positive regulation of protein metabolic process GO:0051247 45 0.029
generation of neurons GO:0048699 235 0.029
organophosphate metabolic process GO:0019637 125 0.029
ribose phosphate metabolic process GO:0019693 99 0.028
organic cyclic compound catabolic process GO:1901361 119 0.028
cellular component morphogenesis GO:0032989 318 0.028
regulation of chromatin modification GO:1903308 2 0.028
macromolecular complex assembly GO:0065003 193 0.028
protein complex biogenesis GO:0070271 186 0.028
regulation of catabolic process GO:0009894 57 0.028
positive regulation of signaling GO:0023056 66 0.027
negative regulation of gene expression epigenetic GO:0045814 2 0.027
response to temperature stimulus GO:0009266 66 0.026
regulation of cytoplasmic transport GO:1903649 3 0.026
cell proliferation GO:0008283 116 0.026
glycosyl compound catabolic process GO:1901658 79 0.026
negative regulation of nematode larval development GO:0061064 208 0.026
cellular catabolic process GO:0044248 199 0.026
nucleotide metabolic process GO:0009117 108 0.025
response to heat GO:0009408 50 0.025
regulation of response to stimulus GO:0048583 243 0.025
cell morphogenesis GO:0000902 163 0.024
purine nucleoside triphosphate metabolic process GO:0009144 87 0.024
carbohydrate derivative metabolic process GO:1901135 141 0.024
purine nucleoside triphosphate catabolic process GO:0009146 72 0.024
cellular protein metabolic process GO:0044267 279 0.023
regulation of protein metabolic process GO:0051246 81 0.023
neuron projection morphogenesis GO:0048812 114 0.023
protein localization GO:0008104 205 0.023
negative regulation of post embryonic development GO:0048581 208 0.023
protein modification process GO:0036211 207 0.023
positive regulation of growth GO:0045927 369 0.023
nucleoside metabolic process GO:0009116 99 0.023
atp catabolic process GO:0006200 27 0.023
regulation of cell proliferation GO:0042127 105 0.023
regulation of catalytic activity GO:0050790 78 0.022
membrane organization GO:0061024 135 0.022
covalent chromatin modification GO:0016569 30 0.022
positive regulation of developmental growth GO:0048639 354 0.022
posttranscriptional regulation of gene expression GO:0010608 166 0.022
regulation of multicellular organism growth GO:0040014 373 0.022
negative regulation of rna metabolic process GO:0051253 53 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.021
cellular localization GO:0051641 360 0.021
ribonucleoside triphosphate metabolic process GO:0009199 87 0.021
ribonucleoside triphosphate catabolic process GO:0009203 72 0.021
secretion by cell GO:0032940 138 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
cellular ketone metabolic process GO:0042180 14 0.020
organelle localization GO:0051640 127 0.020
oocyte construction GO:0007308 2 0.020
negative regulation of cellular biosynthetic process GO:0031327 65 0.020
dna templated transcription elongation GO:0006354 1 0.019
ribonucleoside catabolic process GO:0042454 77 0.019
negative regulation of vulval development GO:0040027 206 0.019
establishment of localization in cell GO:0051649 318 0.018
ribonucleoside monophosphate metabolic process GO:0009161 45 0.018
cellular amino acid metabolic process GO:0006520 15 0.018
cellular amine metabolic process GO:0044106 15 0.017
negative regulation of multicellular organismal process GO:0051241 236 0.017
positive regulation of cell cycle GO:0045787 55 0.017
collagen and cuticulin based cuticle development GO:0040002 99 0.017
membrane invagination GO:0010324 98 0.017
internal peptidyl lysine acetylation GO:0018393 3 0.017
organophosphate catabolic process GO:0046434 81 0.017
engulfment of apoptotic cell GO:0043652 94 0.017
cell morphogenesis involved in differentiation GO:0000904 112 0.017
oocyte axis specification GO:0007309 2 0.017
nucleobase containing compound catabolic process GO:0034655 114 0.017
positive regulation of cellular component organization GO:0051130 34 0.017
phosphorylation GO:0016310 116 0.016
dna templated transcription initiation GO:0006352 3 0.016
nucleoside catabolic process GO:0009164 78 0.016
secretion GO:0046903 147 0.016
ras protein signal transduction GO:0007265 31 0.016
modification dependent macromolecule catabolic process GO:0043632 32 0.016
organonitrogen compound catabolic process GO:1901565 90 0.016
amine metabolic process GO:0009308 15 0.016
mitotic nuclear division GO:0007067 89 0.016
rrna processing GO:0006364 3 0.016
organ morphogenesis GO:0009887 67 0.015
neuron differentiation GO:0030182 217 0.015
cellular protein complex assembly GO:0043623 178 0.015
apoptotic cell clearance GO:0043277 111 0.015
oxoacid metabolic process GO:0043436 47 0.015
nucleotide catabolic process GO:0009166 77 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.015
protein catabolic process GO:0030163 162 0.015
regulation of cellular catabolic process GO:0031329 51 0.015
negative regulation of developmental process GO:0051093 227 0.015
positive regulation of post embryonic development GO:0048582 54 0.015
macromolecule catabolic process GO:0009057 202 0.015
positive regulation of catalytic activity GO:0043085 59 0.014
mrna processing GO:0006397 13 0.014
positive regulation of phosphate metabolic process GO:0045937 56 0.014
internal protein amino acid acetylation GO:0006475 3 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
response to external stimulus GO:0009605 289 0.014
purine containing compound metabolic process GO:0072521 95 0.014
peptidyl lysine acetylation GO:0018394 3 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.013
carboxylic acid metabolic process GO:0019752 34 0.013
regulation of locomotion GO:0040012 161 0.013
ubiquitin dependent protein catabolic process GO:0006511 32 0.013
mitotic g2 m transition checkpoint GO:0044818 1 0.013
adult behavior GO:0030534 3 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.013
cellular response to dna damage stimulus GO:0006974 41 0.013
spindle organization GO:0007051 92 0.012
cellular macromolecule catabolic process GO:0044265 73 0.012
positive regulation of nematode larval development GO:0061063 54 0.012
purine nucleoside monophosphate metabolic process GO:0009126 43 0.012
nucleic acid transport GO:0050657 3 0.012
positive regulation of chromosome organization GO:2001252 2 0.012
neuron projection development GO:0031175 187 0.012
positive regulation of hydrolase activity GO:0051345 38 0.012
chemotaxis GO:0006935 120 0.012
proteolysis GO:0006508 61 0.012
single organism cellular localization GO:1902580 72 0.012
lateral inhibition GO:0046331 3 0.011
sex determination GO:0007530 60 0.011
mitotic sister chromatid segregation GO:0000070 38 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
cuticle development GO:0042335 100 0.011
regulation of transport GO:0051049 91 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
histone h3 k27 demethylation GO:0071557 3 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.011
cell surface receptor signaling pathway GO:0007166 149 0.011
response to uv c GO:0010225 3 0.011
lipid metabolic process GO:0006629 77 0.010
purine ribonucleotide catabolic process GO:0009154 75 0.010

npp-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.027