Caenorhabditis elegans

24 known processes

mca-2 (CELE_R05C11.3)

Protein MCA-2

mca-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.446
Mouse Worm
establishment of localization GO:0051234 1171 0.445
Human Yeast Mouse Rat Worm
post embryonic development GO:0009791 2152 0.393
Worm
transport GO:0006810 1093 0.374
Human Yeast Mouse Rat Worm
locomotion GO:0040011 1634 0.279
single organism localization GO:1902578 518 0.190
Human Yeast Mouse Rat Worm
vesicle mediated transport GO:0016192 852 0.190
Worm
single organism transport GO:0044765 447 0.188
Human Yeast Mouse Rat Worm
gonad development GO:0008406 840 0.184
reproductive system development GO:0061458 850 0.182
development of primary sexual characteristics GO:0045137 840 0.178
embryo development ending in birth or egg hatching GO:0009792 2992 0.174
Worm
reproductive structure development GO:0048608 850 0.168
hermaphrodite genitalia development GO:0040035 734 0.161
sex differentiation GO:0007548 909 0.153
macromolecule catabolic process GO:0009057 202 0.149
genitalia development GO:0048806 741 0.149
endocytosis GO:0006897 819 0.141
Worm
receptor mediated endocytosis GO:0006898 715 0.135
developmental process involved in reproduction GO:0003006 1165 0.133
establishment of localization in cell GO:0051649 318 0.125
Worm
developmental growth GO:0048589 412 0.122
macromolecule localization GO:0033036 771 0.112
response to chemical GO:0042221 356 0.110
Human Rat
single organism reproductive process GO:0044702 1196 0.109
protein metabolic process GO:0019538 422 0.102
Human
gamete generation GO:0007276 461 0.101
multicellular organismal aging GO:0010259 812 0.101
cellular localization GO:0051641 360 0.098
Worm
cell development GO:0048468 696 0.092
Zebrafish Mouse
regulation of biological quality GO:0065008 741 0.092
Human Yeast Mouse Worm
neuron development GO:0048666 199 0.089
Zebrafish Mouse
organic substance catabolic process GO:1901575 294 0.089
Human Yeast Mouse Rat Worm
generation of neurons GO:0048699 235 0.087
Human Zebrafish Mouse
anion transport GO:0006820 30 0.086
positive regulation of growth GO:0045927 369 0.082
sexual reproduction GO:0019953 546 0.081
multicellular organismal reproductive process GO:0048609 815 0.081
catabolic process GO:0009056 318 0.079
Human Yeast Mouse Rat Worm
organ development GO:0048513 1102 0.078
Zebrafish Mouse Rat
growth GO:0040007 562 0.078
determination of adult lifespan GO:0008340 812 0.077
body morphogenesis GO:0010171 620 0.077
positive regulation of cellular process GO:0048522 332 0.075
Human
maintenance of location GO:0051235 580 0.073
single organism signaling GO:0044700 401 0.072
Human Mouse
ion transmembrane transport GO:0034220 91 0.070
Human Yeast Mouse Rat Worm
lipid localization GO:0010876 573 0.069
organelle organization GO:0006996 783 0.067
Mouse
secretion GO:0046903 147 0.067
Mouse Worm
protein localization GO:0008104 205 0.066
phosphate containing compound metabolic process GO:0006796 232 0.065
Human Yeast Mouse Rat Worm
biosynthetic process GO:0009058 323 0.065
Human
neuron differentiation GO:0030182 217 0.065
Human Zebrafish Mouse
signaling GO:0023052 401 0.064
Human Mouse
regulation of locomotion GO:0040012 161 0.063
Worm
positive regulation of metabolic process GO:0009893 187 0.063
Human
secretion by cell GO:0032940 138 0.063
Worm
programmed cell death GO:0012501 500 0.063
lipid storage GO:0019915 565 0.062
post embryonic organ development GO:0048569 336 0.062
collagen and cuticulin based cuticle development GO:0040002 99 0.061
regulation of developmental process GO:0050793 684 0.060
cellular response to chemical stimulus GO:0070887 129 0.060
Human Rat
nucleobase containing compound metabolic process GO:0006139 406 0.060
Human Yeast Mouse Rat Worm
negative regulation of biological process GO:0048519 567 0.060
Human Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.060
positive regulation of developmental growth GO:0048639 354 0.060
cellular component movement GO:0006928 388 0.060
organic acid metabolic process GO:0006082 47 0.057
Human
aging GO:0007568 812 0.057
Rat
regulation of signaling GO:0023051 172 0.057
Human Mouse
axon development GO:0061564 163 0.056
multi organism reproductive process GO:0044703 867 0.056
regulation of multicellular organismal process GO:0051239 726 0.054
regulation of growth GO:0040008 409 0.053
death GO:0016265 547 0.052
protein catabolic process GO:0030163 162 0.052
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.051
cellular component morphogenesis GO:0032989 318 0.051
Mouse
multicellular organism growth GO:0035264 385 0.051
cell migration GO:0016477 306 0.051
multicellular organism reproduction GO:0032504 819 0.051
regulation of multicellular organism growth GO:0040014 373 0.050
molting cycle GO:0042303 281 0.049
cellular protein metabolic process GO:0044267 279 0.049
Human
neuron projection guidance GO:0097485 82 0.049
regulation of cell communication GO:0010646 176 0.049
Human Mouse
macromolecule modification GO:0043412 218 0.048
Human
positive regulation of multicellular organism growth GO:0040018 352 0.047
cell death GO:0008219 547 0.047
cytoskeleton organization GO:0007010 339 0.047
negative regulation of cellular process GO:0048523 239 0.046
Human
positive regulation of cellular metabolic process GO:0031325 178 0.045
Human
apoptotic process GO:0006915 478 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.043
cuticle development GO:0042335 100 0.043
cellular component biogenesis GO:0044085 297 0.043
embryonic body morphogenesis GO:0010172 49 0.043
phosphorus metabolic process GO:0006793 232 0.042
Human Yeast Mouse Rat Worm
cellular catabolic process GO:0044248 199 0.042
Human Yeast Mouse Rat Worm
cell motility GO:0048870 313 0.041
protein modification process GO:0036211 207 0.041
Human
organelle assembly GO:0070925 214 0.041
regulation of metabolic process GO:0019222 478 0.041
Human
behavior GO:0007610 527 0.040
Mouse
regulation of response to stimulus GO:0048583 243 0.040
Human Mouse
regulation of multicellular organismal development GO:2000026 317 0.040
single organism organelle organization GO:1902589 501 0.040
female gamete generation GO:0007292 254 0.039
positive regulation of developmental process GO:0051094 408 0.039
localization of cell GO:0051674 313 0.039
nervous system development GO:0007399 253 0.038
Human Zebrafish Mouse Rat
phagocytosis GO:0006909 115 0.038
muscle structure development GO:0061061 191 0.038
vulval development GO:0040025 333 0.037
regulation of developmental growth GO:0048638 389 0.037
synaptic transmission GO:0007268 106 0.037
Mouse
neuron projection development GO:0031175 187 0.037
organonitrogen compound metabolic process GO:1901564 151 0.036
Human Yeast Mouse Rat Worm
signal transduction GO:0007165 317 0.036
Human
neurogenesis GO:0022008 236 0.036
Human Zebrafish Mouse
organic substance biosynthetic process GO:1901576 323 0.035
Human
embryonic morphogenesis GO:0048598 152 0.035
Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.035
gene expression GO:0010467 412 0.035
Human
axon guidance GO:0007411 82 0.035
protein complex subunit organization GO:0071822 280 0.034
regulation of phosphorus metabolic process GO:0051174 81 0.034
Human
meiotic cell cycle GO:0051321 335 0.034
carboxylic acid metabolic process GO:0019752 34 0.034
Human
response to topologically incorrect protein GO:0035966 82 0.034
regulation of macromolecule metabolic process GO:0060255 421 0.033
Human
regulation of localization GO:0032879 194 0.033
Mouse Worm
organ morphogenesis GO:0009887 67 0.033
Mouse
macromolecule biosynthetic process GO:0009059 250 0.033
Human
peptidyl amino acid modification GO:0018193 58 0.033
Human
cellular component assembly involved in morphogenesis GO:0010927 183 0.032
multicellular organismal reproductive behavior GO:0033057 384 0.032
phagocytosis engulfment GO:0006911 98 0.031
ion transport GO:0006811 113 0.031
Human Yeast Mouse Rat Worm
transmembrane transport GO:0055085 110 0.031
Human Yeast Mouse Rat Worm
system process GO:0003008 136 0.031
Human Zebrafish Mouse
cell cycle GO:0007049 526 0.031
protein phosphorylation GO:0006468 85 0.031
Human
positive regulation of macromolecule metabolic process GO:0010604 149 0.030
Human
multi organism reproductive behavior GO:0044705 387 0.029
cellular biosynthetic process GO:0044249 315 0.029
Human
multi multicellular organism process GO:0044706 390 0.029
oxoacid metabolic process GO:0043436 47 0.029
Human
negative regulation of metabolic process GO:0009892 240 0.029
Human
response to oxygen containing compound GO:1901700 44 0.028
Human Rat
response to external stimulus GO:0009605 289 0.028
Mouse Rat
regulation of cellular component organization GO:0051128 248 0.028
Worm
response to abiotic stimulus GO:0009628 152 0.027
Human Mouse Rat
regulation of nematode larval development GO:0061062 260 0.027
apoptotic cell clearance GO:0043277 111 0.027
multi organism behavior GO:0051705 389 0.027
positive regulation of transport GO:0051050 32 0.026
Mouse Worm
regulation of cell cycle GO:0051726 194 0.026
small molecule metabolic process GO:0044281 186 0.026
Human Yeast Mouse Rat Worm
transcription dna templated GO:0006351 168 0.026
Human
regulation of gene expression GO:0010468 366 0.025
Human
reproductive behavior GO:0019098 387 0.025
membrane invagination GO:0010324 98 0.024
ras protein signal transduction GO:0007265 31 0.024
cellular amine metabolic process GO:0044106 15 0.024
Human
regulation of post embryonic development GO:0048580 260 0.024
cellular protein modification process GO:0006464 207 0.023
Human
negative regulation of macromolecule metabolic process GO:0010605 229 0.023
taxis GO:0042330 128 0.023
phosphorylation GO:0016310 116 0.023
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
Human
cellular macromolecule biosynthetic process GO:0034645 247 0.022
Human
regulation of cell differentiation GO:0045595 81 0.022
actin cytoskeleton organization GO:0030036 184 0.022
regulation of rna biosynthetic process GO:2001141 165 0.022
Human
actin filament based process GO:0030029 191 0.022
engulfment of apoptotic cell GO:0043652 94 0.022
regulation of vulval development GO:0040028 248 0.022
response to wounding GO:0009611 4 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
Human
regulation of neurotransmitter levels GO:0001505 36 0.021
regulation of cellular metabolic process GO:0031323 305 0.021
Human
cell projection morphogenesis GO:0048858 148 0.021
macromolecular complex subunit organization GO:0043933 320 0.021
positive regulation of biosynthetic process GO:0009891 109 0.021
actomyosin structure organization GO:0031032 154 0.020
negative regulation of developmental process GO:0051093 227 0.020
fertilization GO:0009566 63 0.020
neuron projection morphogenesis GO:0048812 114 0.020
nucleoside monophosphate metabolic process GO:0009123 46 0.020
Human Yeast Mouse Rat Worm
skeletal muscle organ development GO:0060538 3 0.020
meiotic nuclear division GO:0007126 300 0.020
regulation of intracellular signal transduction GO:1902531 77 0.020
Human
erbb signaling pathway GO:0038127 9 0.020
regulation of catabolic process GO:0009894 57 0.019
Human
cellular amino acid metabolic process GO:0006520 15 0.019
Human
muscle cell development GO:0055001 158 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.019
Mouse
membrane organization GO:0061024 135 0.019
oviposition GO:0018991 364 0.019
negative regulation of gene expression GO:0010629 217 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
Mouse
organic substance transport GO:0071702 113 0.019
glycosyl compound catabolic process GO:1901658 79 0.019
Human Yeast Mouse Rat Worm
myofibril assembly GO:0030239 154 0.019
cellular response to stress GO:0033554 162 0.019
cell cycle process GO:0022402 482 0.019
peptidyl tyrosine phosphorylation GO:0018108 2 0.019
heterocycle catabolic process GO:0046700 119 0.018
Human Yeast Mouse Rat Worm
single organism catabolic process GO:0044712 129 0.018
Human Yeast Mouse Rat Worm
striated muscle cell differentiation GO:0051146 158 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.018
cell morphogenesis involved in differentiation GO:0000904 112 0.018
Mouse
response to inorganic substance GO:0010035 50 0.018
Human
muscle cell differentiation GO:0042692 171 0.018
tube development GO:0035295 126 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
Human
purine nucleoside triphosphate metabolic process GO:0009144 87 0.018
Human Yeast Mouse Rat Worm
negative regulation of multicellular organismal process GO:0051241 236 0.018
Human Mouse
myosin filament assembly GO:0031034 138 0.017
cellular response to nutrient levels GO:0031669 13 0.017
Rat
germ cell development GO:0007281 351 0.017
myosin filament organization GO:0031033 138 0.017
organic cyclic compound biosynthetic process GO:1901362 195 0.017
Human
cellular component assembly GO:0022607 293 0.017
sensory organ morphogenesis GO:0090596 2 0.017
Mouse
negative regulation of nematode larval development GO:0061064 208 0.017
striated muscle cell development GO:0055002 157 0.017
chemotaxis GO:0006935 120 0.016
cellular ketone metabolic process GO:0042180 14 0.016
Human
positive regulation of catabolic process GO:0009896 38 0.016
single organism intracellular transport GO:1902582 70 0.016
regulation of signal transduction GO:0009966 135 0.016
Human
posttranscriptional regulation of gene expression GO:0010608 166 0.016
amine metabolic process GO:0009308 15 0.016
Human
striated muscle myosin thick filament assembly GO:0071688 138 0.016
inorganic ion transmembrane transport GO:0098660 54 0.016
Human Yeast Mouse Rat Worm
epidermal growth factor receptor signaling pathway GO:0007173 9 0.016
dauer larval development GO:0040024 92 0.016
neuromuscular junction development GO:0007528 2 0.016
positive regulation of phosphate metabolic process GO:0045937 56 0.016
Human
positive regulation of cellular catabolic process GO:0031331 35 0.016
positive regulation of locomotion GO:0040017 42 0.016
Worm
regulation of mitotic cell cycle GO:0007346 76 0.016
cell part morphogenesis GO:0032990 152 0.015
regulation of rna metabolic process GO:0051252 173 0.015
Human
signal release GO:0023061 28 0.015
muscle tissue development GO:0060537 1 0.015
organelle fission GO:0048285 363 0.015
nucleobase containing compound biosynthetic process GO:0034654 184 0.015
Human
purine ribonucleotide catabolic process GO:0009154 75 0.015
Human Yeast Mouse Rat Worm
positive regulation of nucleotide catabolic process GO:0030813 28 0.015
positive regulation of molecular function GO:0044093 61 0.015
Human
nucleobase containing compound catabolic process GO:0034655 114 0.015
Human Yeast Mouse Rat Worm
regulation of meiotic cell cycle GO:0051445 136 0.015
regulation of cytoplasmic transport GO:1903649 3 0.015
tissue morphogenesis GO:0048729 65 0.014
intracellular transport GO:0046907 77 0.014
regeneration GO:0031099 4 0.014
organic cyclic compound catabolic process GO:1901361 119 0.014
Human Yeast Mouse Rat Worm
nucleic acid metabolic process GO:0090304 299 0.014
Human
positive regulation of nucleoside metabolic process GO:0045979 28 0.014
response to biotic stimulus GO:0009607 101 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
Human
endoplasmic reticulum unfolded protein response GO:0030968 66 0.014
cell surface receptor signaling pathway GO:0007166 149 0.013
Human
regulation of organelle organization GO:0033043 164 0.013
negative regulation of post embryonic development GO:0048581 208 0.013
positive regulation of transcription dna templated GO:0045893 102 0.013
carbohydrate derivative metabolic process GO:1901135 141 0.013
Human Yeast Mouse Rat Worm
rna metabolic process GO:0016070 228 0.013
Human
regulation of nitrogen compound metabolic process GO:0051171 222 0.013
Human
chromosome segregation GO:0007059 180 0.013
cell projection organization GO:0030030 231 0.013
Mouse
cellular macromolecular complex assembly GO:0034622 184 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.013
Human
regulation of cellular localization GO:0060341 42 0.013
protein oligomerization GO:0051259 4 0.012
protein complex biogenesis GO:0070271 186 0.012
head development GO:0060322 1 0.012
Mouse Rat
defense response to other organism GO:0098542 100 0.012
response to acid chemical GO:0001101 4 0.012
Human
cellular protein localization GO:0034613 75 0.012
regulation of phosphate metabolic process GO:0019220 81 0.012
Human
defense response GO:0006952 296 0.012
cell recognition GO:0008037 85 0.012
regulation of primary metabolic process GO:0080090 292 0.012
Human
meiotic chromosome segregation GO:0045132 139 0.011
oogenesis GO:0048477 229 0.011
neurotransmitter transport GO:0006836 32 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
positive regulation of catalytic activity GO:0043085 59 0.011
Human
neurotransmitter secretion GO:0007269 26 0.011
cellular response to topologically incorrect protein GO:0035967 76 0.011
negative regulation of vulval development GO:0040027 206 0.011
positive regulation of phosphorus metabolic process GO:0010562 56 0.011
Human
tissue development GO:0009888 112 0.011
Zebrafish Mouse Rat
posttranscriptional gene silencing by rna GO:0035194 143 0.011
heterocycle biosynthetic process GO:0018130 187 0.011
Human
inorganic cation transmembrane transport GO:0098662 46 0.011
Human Yeast Mouse Rat Worm
adult behavior GO:0030534 3 0.011
response to temperature stimulus GO:0009266 66 0.011
Rat
negative regulation of cellular metabolic process GO:0031324 95 0.010
Human
intracellular signal transduction GO:0035556 96 0.010
Human
aromatic compound catabolic process GO:0019439 116 0.010
Human Yeast Mouse Rat Worm
negative regulation of transcription dna templated GO:0045892 53 0.010
response to unfolded protein GO:0006986 71 0.010
cellular protein complex assembly GO:0043623 178 0.010
homeostatic process GO:0042592 51 0.010
Human Yeast Mouse Worm
inductive cell migration GO:0040039 145 0.010
negative regulation of neurogenesis GO:0050768 4 0.010
regulation of transport GO:0051049 91 0.010
Mouse Worm

mca-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
Human
nervous system disease DOID:863 0 0.017
Human
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011