Caenorhabditis elegans

58 known processes

mdh-2 (CELE_F20H11.3)

Protein MDH-2

mdh-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.716
embryo development GO:0009790 3052 0.680
post embryonic development GO:0009791 2152 0.610
transport GO:0006810 1093 0.356
aging GO:0007568 812 0.349
determination of adult lifespan GO:0008340 812 0.342
locomotion GO:0040011 1634 0.341
multicellular organismal aging GO:0010259 812 0.324
vesicle mediated transport GO:0016192 852 0.286
cellular localization GO:0051641 360 0.225
receptor mediated endocytosis GO:0006898 715 0.205
establishment of localization GO:0051234 1171 0.197
endocytosis GO:0006897 819 0.174
single organism localization GO:1902578 518 0.170
phosphorus metabolic process GO:0006793 232 0.169
organ development GO:0048513 1102 0.148
Fly
catabolic process GO:0009056 318 0.141
head development GO:0060322 1 0.136
organelle organization GO:0006996 783 0.134
phosphate containing compound metabolic process GO:0006796 232 0.130
single organism transport GO:0044765 447 0.128
body morphogenesis GO:0010171 620 0.128
cell development GO:0048468 696 0.125
response to abiotic stimulus GO:0009628 152 0.117
multicellular organism reproduction GO:0032504 819 0.109
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.107
nervous system development GO:0007399 253 0.106
single organism organelle organization GO:1902589 501 0.102
developmental growth GO:0048589 412 0.101
apoptotic process GO:0006915 478 0.095
Fly
gamete generation GO:0007276 461 0.094
regulation of multicellular organism growth GO:0040014 373 0.087
regulation of biological quality GO:0065008 741 0.087
single organism reproductive process GO:0044702 1196 0.086
multi organism reproductive process GO:0044703 867 0.086
glycosyl compound metabolic process GO:1901657 100 0.083
sex differentiation GO:0007548 909 0.083
cell fate commitment GO:0045165 139 0.080
oxoacid metabolic process GO:0043436 47 0.078
Human
positive regulation of multicellular organism growth GO:0040018 352 0.078
macromolecule localization GO:0033036 771 0.078
death GO:0016265 547 0.077
Fly
negative regulation of biological process GO:0048519 567 0.076
response to external stimulus GO:0009605 289 0.075
regulation of developmental process GO:0050793 684 0.075
macromolecular complex subunit organization GO:0043933 320 0.075
cellular catabolic process GO:0044248 199 0.073
single organism catabolic process GO:0044712 129 0.072
growth GO:0040007 562 0.070
purine nucleotide metabolic process GO:0006163 95 0.070
ribonucleoside triphosphate metabolic process GO:0009199 87 0.067
signaling GO:0023052 401 0.067
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.064
cell cycle GO:0007049 526 0.063
ribonucleoside monophosphate metabolic process GO:0009161 45 0.063
organic substance transport GO:0071702 113 0.062
cellular component movement GO:0006928 388 0.062
maintenance of location GO:0051235 580 0.062
sexual reproduction GO:0019953 546 0.061
transmembrane transport GO:0055085 110 0.061
phosphorylation GO:0016310 116 0.059
localization of cell GO:0051674 313 0.059
carbohydrate derivative metabolic process GO:1901135 141 0.057
multicellular organismal reproductive process GO:0048609 815 0.057
atp metabolic process GO:0046034 42 0.057
programmed cell death GO:0012501 500 0.056
Fly
developmental process involved in reproduction GO:0003006 1165 0.056
tube development GO:0035295 126 0.055
lipid localization GO:0010876 573 0.054
cell migration GO:0016477 306 0.054
organophosphate metabolic process GO:0019637 125 0.054
cellular respiration GO:0045333 9 0.054
Fly
organelle fission GO:0048285 363 0.053
purine nucleoside triphosphate metabolic process GO:0009144 87 0.053
regulation of growth GO:0040008 409 0.052
lipid storage GO:0019915 565 0.052
establishment of localization in cell GO:0051649 318 0.051
negative regulation of cellular process GO:0048523 239 0.050
organic substance catabolic process GO:1901575 294 0.050
meiotic cell cycle GO:0051321 335 0.049
purine nucleoside monophosphate metabolic process GO:0009126 43 0.049
positive regulation of multicellular organismal process GO:0051240 417 0.049
nucleoside monophosphate metabolic process GO:0009123 46 0.049
positive regulation of cellular process GO:0048522 332 0.048
Fly
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.048
tube formation GO:0035148 2 0.047
protein complex subunit organization GO:0071822 280 0.045
molting cycle GO:0042303 281 0.045
reproductive structure development GO:0048608 850 0.045
organic acid metabolic process GO:0006082 47 0.045
Human
ribose phosphate metabolic process GO:0019693 99 0.045
hermaphrodite genitalia development GO:0040035 734 0.043
cellular component biogenesis GO:0044085 297 0.043
organ morphogenesis GO:0009887 67 0.043
Fly
regulation of cell communication GO:0010646 176 0.042
ion transport GO:0006811 113 0.042
cell cycle process GO:0022402 482 0.042
cell cell signaling GO:0007267 118 0.042
regulation of cation channel activity GO:2001257 3 0.041
regulation of gene expression GO:0010468 366 0.040
genitalia development GO:0048806 741 0.040
nucleotide metabolic process GO:0009117 108 0.040
regulation of metabolic process GO:0019222 478 0.040
Fly
regulation of signaling GO:0023051 172 0.040
cell death GO:0008219 547 0.039
Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.038
development of primary sexual characteristics GO:0045137 840 0.038
small molecule metabolic process GO:0044281 186 0.038
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.038
germ cell development GO:0007281 351 0.037
cellular component assembly GO:0022607 293 0.037
purine ribonucleoside metabolic process GO:0046128 92 0.037
multicellular organism growth GO:0035264 385 0.036
positive regulation of developmental growth GO:0048639 354 0.035
regulation of developmental growth GO:0048638 389 0.035
nucleoside phosphate metabolic process GO:0006753 108 0.033
establishment of organelle localization GO:0051656 123 0.033
female gamete generation GO:0007292 254 0.033
reproductive system development GO:0061458 850 0.033
system process GO:0003008 136 0.033
oxidation reduction process GO:0055114 59 0.033
Human Fly
striated muscle cell differentiation GO:0051146 158 0.033
nucleobase containing compound catabolic process GO:0034655 114 0.032
gonad development GO:0008406 840 0.032
epithelium development GO:0060429 68 0.032
single organism signaling GO:0044700 401 0.032
purine ribonucleotide metabolic process GO:0009150 95 0.031
cell part morphogenesis GO:0032990 152 0.031
organonitrogen compound metabolic process GO:1901564 151 0.030
positive regulation of growth GO:0045927 369 0.030
response to other organism GO:0051707 101 0.030
nucleoside metabolic process GO:0009116 99 0.030
reproductive behavior GO:0019098 387 0.030
regulation of multicellular organismal process GO:0051239 726 0.030
negative regulation of cell communication GO:0010648 61 0.029
meiotic nuclear division GO:0007126 300 0.029
multi organism reproductive behavior GO:0044705 387 0.029
secretion GO:0046903 147 0.029
nucleoside phosphate catabolic process GO:1901292 77 0.028
embryonic morphogenesis GO:0048598 152 0.027
carboxylic acid metabolic process GO:0019752 34 0.026
Human
nucleoside triphosphate metabolic process GO:0009141 87 0.026
gene expression GO:0010467 412 0.026
Fly
nucleobase containing compound metabolic process GO:0006139 406 0.026
muscle structure development GO:0061061 191 0.025
regulation of transport GO:0051049 91 0.024
positive regulation of developmental process GO:0051094 408 0.024
purine nucleoside metabolic process GO:0042278 92 0.023
organelle localization GO:0051640 127 0.023
behavior GO:0007610 527 0.022
response to chemical GO:0042221 356 0.022
macromolecule catabolic process GO:0009057 202 0.022
cell motility GO:0048870 313 0.022
regulation of cellular component organization GO:0051128 248 0.022
vulval development GO:0040025 333 0.022
regulation of lipid metabolic process GO:0019216 4 0.022
positive regulation of intracellular transport GO:0032388 2 0.021
ion transmembrane transport GO:0034220 91 0.021
actin cytoskeleton organization GO:0030036 184 0.021
ribonucleotide catabolic process GO:0009261 75 0.021
nucleobase containing small molecule metabolic process GO:0055086 115 0.021
nucleoside triphosphate catabolic process GO:0009143 72 0.021
regulation of cell differentiation GO:0045595 81 0.021
cell division GO:0051301 262 0.021
signal transduction GO:0007165 317 0.020
neurogenesis GO:0022008 236 0.020
apoptotic cell clearance GO:0043277 111 0.020
posttranscriptional gene silencing GO:0016441 143 0.019
membrane organization GO:0061024 135 0.019
epithelial tube morphogenesis GO:0060562 1 0.019
purine containing compound metabolic process GO:0072521 95 0.019
inorganic ion transmembrane transport GO:0098660 54 0.018
spermatogenesis GO:0007283 41 0.018
multi organism behavior GO:0051705 389 0.018
gene silencing by rna GO:0031047 143 0.018
regulation of intracellular signal transduction GO:1902531 77 0.018
homeostatic process GO:0042592 51 0.018
muscle cell development GO:0055001 158 0.017
organelle assembly GO:0070925 214 0.017
regulation of hormone secretion GO:0046883 2 0.017
cellular response to stress GO:0033554 162 0.017
rna interference GO:0016246 137 0.017
purine nucleoside catabolic process GO:0006152 75 0.017
ribonucleoside triphosphate catabolic process GO:0009203 72 0.017
synaptic transmission GO:0007268 106 0.017
ribonucleotide metabolic process GO:0009259 99 0.017
myosin filament assembly GO:0031034 138 0.017
glycosyl compound catabolic process GO:1901658 79 0.016
defense response GO:0006952 296 0.016
cellular component morphogenesis GO:0032989 318 0.016
posttranscriptional gene silencing by rna GO:0035194 143 0.016
ribonucleoside catabolic process GO:0042454 77 0.016
chromosome organization GO:0051276 104 0.016
generation of neurons GO:0048699 235 0.016
macromolecular complex assembly GO:0065003 193 0.016
atp catabolic process GO:0006200 27 0.016
aromatic compound catabolic process GO:0019439 116 0.016
phagocytosis engulfment GO:0006911 98 0.016
monovalent inorganic cation transport GO:0015672 33 0.016
response to biotic stimulus GO:0009607 101 0.016
phagocytosis GO:0006909 115 0.016
regulation of primary metabolic process GO:0080090 292 0.016
Fly
posttranscriptional regulation of gene expression GO:0010608 166 0.016
response to mechanical stimulus GO:0009612 28 0.015
tricarboxylic acid metabolic process GO:0072350 1 0.015
purine nucleoside triphosphate catabolic process GO:0009146 72 0.015
protein complex biogenesis GO:0070271 186 0.015
regulation of signal transduction GO:0009966 135 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
biosynthetic process GO:0009058 323 0.015
generation of precursor metabolites and energy GO:0006091 18 0.015
Fly
regulation of response to stimulus GO:0048583 243 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.015
establishment or maintenance of cell polarity GO:0007163 63 0.015
cellular biosynthetic process GO:0044249 315 0.015
ion homeostasis GO:0050801 21 0.015
male gamete generation GO:0048232 41 0.014
nucleoside catabolic process GO:0009164 78 0.014
microtubule based process GO:0007017 182 0.014
inorganic cation transmembrane transport GO:0098662 46 0.014
purine ribonucleoside catabolic process GO:0046130 75 0.014
purine nucleoside monophosphate catabolic process GO:0009128 28 0.014
oviposition GO:0018991 364 0.014
establishment of cell polarity GO:0030010 46 0.013
multi multicellular organism process GO:0044706 390 0.013
nitrogen compound transport GO:0071705 49 0.013
somatic muscle development GO:0007525 1 0.013
carbohydrate derivative catabolic process GO:1901136 82 0.013
regulation of localization GO:0032879 194 0.013
regulation of cell cycle GO:0051726 194 0.013
multicellular organismal reproductive behavior GO:0033057 384 0.013
regulation of organelle organization GO:0033043 164 0.013
ribonucleoside metabolic process GO:0009119 98 0.013
organic cyclic compound catabolic process GO:1901361 119 0.013
membrane invagination GO:0010324 98 0.012
regulation of cytoplasmic transport GO:1903649 3 0.012
heterocycle catabolic process GO:0046700 119 0.012
regulation of ion transport GO:0043269 39 0.012
regulation of cell proliferation GO:0042127 105 0.012
cell projection assembly GO:0030031 35 0.012
negative regulation of developmental process GO:0051093 227 0.012
single organism membrane organization GO:0044802 35 0.012
mitotic cell cycle process GO:1903047 194 0.011
pattern specification process GO:0007389 59 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
cell proliferation GO:0008283 116 0.011
eating behavior GO:0042755 59 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
regulation of nematode larval development GO:0061062 260 0.011
secretion by cell GO:0032940 138 0.011
protein metabolic process GO:0019538 422 0.011
Human Fly
purine nucleotide catabolic process GO:0006195 75 0.011
nucleotide catabolic process GO:0009166 77 0.011
negative regulation of macromolecule metabolic process GO:0010605 229 0.011
purine ribonucleotide catabolic process GO:0009154 75 0.011
protein localization GO:0008104 205 0.011
organophosphate catabolic process GO:0046434 81 0.011
positive regulation of cell communication GO:0010647 69 0.011
myosin filament organization GO:0031033 138 0.011
positive regulation of transport GO:0051050 32 0.010
intracellular signal transduction GO:0035556 96 0.010
macromolecule modification GO:0043412 218 0.010
Human
protein complex assembly GO:0006461 186 0.010
regulation of post embryonic development GO:0048580 260 0.010
striated muscle cell development GO:0055002 157 0.010
post embryonic organ development GO:0048569 336 0.010

mdh-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.093
disease of cellular proliferation DOID:14566 0 0.084
cancer DOID:162 0 0.066
gastrointestinal system cancer DOID:3119 0 0.024
organ system cancer DOID:0050686 0 0.024
inherited metabolic disorder DOID:655 0 0.022
disease of anatomical entity DOID:7 0 0.012