Caenorhabditis elegans

24 known processes

his-58 (CELE_F54E12.4)

Protein HIS-58

his-58 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.333
post embryonic development GO:0009791 2152 0.328
Worm
locomotion GO:0040011 1634 0.326
embryo development GO:0009790 3052 0.322
developmental process involved in reproduction GO:0003006 1165 0.228
organ development GO:0048513 1102 0.204
single organism reproductive process GO:0044702 1196 0.199
hermaphrodite genitalia development GO:0040035 734 0.196
reproductive structure development GO:0048608 850 0.191
gonad development GO:0008406 840 0.189
sex differentiation GO:0007548 909 0.179
development of primary sexual characteristics GO:0045137 840 0.174
reproductive system development GO:0061458 850 0.163
multi organism reproductive process GO:0044703 867 0.136
Worm
multicellular organism reproduction GO:0032504 819 0.133
Worm
genitalia development GO:0048806 741 0.132
multicellular organismal reproductive process GO:0048609 815 0.130
Worm
organelle organization GO:0006996 783 0.121
Yeast
multicellular organismal reproductive behavior GO:0033057 384 0.115
Worm
multi organism reproductive behavior GO:0044705 387 0.109
Worm
multi multicellular organism process GO:0044706 390 0.108
Worm
defense response GO:0006952 296 0.103
Worm
establishment of localization GO:0051234 1171 0.100
multicellular organismal aging GO:0010259 812 0.099
oviposition GO:0018991 364 0.096
Worm
vesicle mediated transport GO:0016192 852 0.095
multi organism behavior GO:0051705 389 0.094
Worm
endocytosis GO:0006897 819 0.089
body morphogenesis GO:0010171 620 0.088
transport GO:0006810 1093 0.087
aging GO:0007568 812 0.087
determination of adult lifespan GO:0008340 812 0.086
macromolecule localization GO:0033036 771 0.085
behavior GO:0007610 527 0.083
Worm
cell death GO:0008219 547 0.083
negative regulation of biological process GO:0048519 567 0.080
Yeast
reproductive behavior GO:0019098 387 0.080
Worm
digestive system development GO:0055123 122 0.079
Worm
transcription dna templated GO:0006351 168 0.079
Yeast
digestive tract development GO:0048565 122 0.078
Worm
regulation of biological quality GO:0065008 741 0.076
regulation of metabolic process GO:0019222 478 0.076
Yeast
regulation of macromolecule metabolic process GO:0060255 421 0.074
Yeast
receptor mediated endocytosis GO:0006898 715 0.073
rna metabolic process GO:0016070 228 0.072
Yeast
gene expression GO:0010467 412 0.071
Yeast
death GO:0016265 547 0.071
negative regulation of gene expression epigenetic GO:0045814 2 0.070
maintenance of location GO:0051235 580 0.067
lipid localization GO:0010876 573 0.066
regulation of cellular metabolic process GO:0031323 305 0.066
Yeast
nucleobase containing compound metabolic process GO:0006139 406 0.065
Yeast
lipid storage GO:0019915 565 0.065
regulation of primary metabolic process GO:0080090 292 0.065
Yeast
cellular biosynthetic process GO:0044249 315 0.064
Yeast
macromolecule biosynthetic process GO:0009059 250 0.063
Yeast
biosynthetic process GO:0009058 323 0.063
Yeast
regulation of multicellular organismal process GO:0051239 726 0.063
cell development GO:0048468 696 0.062
tube development GO:0035295 126 0.060
Worm
regulation of gene expression GO:0010468 366 0.060
Yeast
programmed cell death GO:0012501 500 0.058
apoptotic process GO:0006915 478 0.057
meiotic cell cycle GO:0051321 335 0.056
regulation of developmental process GO:0050793 684 0.056
single organism transport GO:0044765 447 0.054
sexual reproduction GO:0019953 546 0.054
transcription from rna polymerase ii promoter GO:0006366 149 0.054
Yeast
cellular macromolecule biosynthetic process GO:0034645 247 0.053
Yeast
nucleic acid metabolic process GO:0090304 299 0.053
Yeast
cell cycle GO:0007049 526 0.053
single organism localization GO:1902578 518 0.052
growth GO:0040007 562 0.052
regulation of transcription dna templated GO:0006355 164 0.051
Yeast
negative regulation of cellular process GO:0048523 239 0.050
Yeast
cell cycle process GO:0022402 482 0.050
negative regulation of gene expression GO:0010629 217 0.050
Yeast
molting cycle GO:0042303 281 0.048
pharynx development GO:0060465 51 0.048
Worm
aromatic compound biosynthetic process GO:0019438 192 0.047
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.047
Yeast
rna biosynthetic process GO:0032774 169 0.047
Yeast
organic substance biosynthetic process GO:1901576 323 0.047
Yeast
developmental growth GO:0048589 412 0.046
regulation of multicellular organism growth GO:0040014 373 0.045
regulation of nitrogen compound metabolic process GO:0051171 222 0.045
Yeast
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.044
Yeast
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.044
positive regulation of developmental process GO:0051094 408 0.044
regulation of cellular biosynthetic process GO:0031326 189 0.044
Yeast
regulation of gene expression epigenetic GO:0040029 163 0.044
positive regulation of developmental growth GO:0048639 354 0.044
positive regulation of multicellular organism growth GO:0040018 352 0.044
macromolecular complex subunit organization GO:0043933 320 0.043
Yeast
meiotic cell cycle process GO:1903046 170 0.043
regulation of developmental growth GO:0048638 389 0.043
multicellular organism growth GO:0035264 385 0.042
protein metabolic process GO:0019538 422 0.042
regulation of growth GO:0040008 409 0.042
organelle fission GO:0048285 363 0.042
positive regulation of multicellular organismal process GO:0051240 417 0.042
nucleic acid templated transcription GO:0097659 169 0.041
Yeast
regulation of rna biosynthetic process GO:2001141 165 0.041
Yeast
single organism organelle organization GO:1902589 501 0.041
cellular localization GO:0051641 360 0.041
heterocycle biosynthetic process GO:0018130 187 0.041
Yeast
negative regulation of metabolic process GO:0009892 240 0.040
Yeast
regulation of nucleic acid templated transcription GO:1903506 165 0.040
Yeast
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.039
Yeast
positive regulation of growth GO:0045927 369 0.039
organic cyclic compound biosynthetic process GO:1901362 195 0.039
Yeast
regulation of macromolecule biosynthetic process GO:0010556 189 0.039
Yeast
regulation of biosynthetic process GO:0009889 189 0.038
Yeast
head development GO:0060322 1 0.038
innate immune response GO:0045087 190 0.037
Worm
nucleobase containing compound biosynthetic process GO:0034654 184 0.037
Yeast
cellular nitrogen compound biosynthetic process GO:0044271 192 0.037
Yeast
immune response GO:0006955 192 0.037
Worm
negative regulation of macromolecule metabolic process GO:0010605 229 0.036
Yeast
cellular component morphogenesis GO:0032989 318 0.036
meiotic nuclear division GO:0007126 300 0.036
gamete generation GO:0007276 461 0.035
single organism signaling GO:0044700 401 0.034
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.034
catabolic process GO:0009056 318 0.033
gene silencing GO:0016458 143 0.033
response to wounding GO:0009611 4 0.032
cellular response to dna damage stimulus GO:0006974 41 0.032
Yeast
establishment of localization in cell GO:0051649 318 0.032
signaling GO:0023052 401 0.032
germ cell development GO:0007281 351 0.032
cell division GO:0051301 262 0.031
vulval development GO:0040025 333 0.030
nucleus organization GO:0006997 38 0.030
protein complex subunit organization GO:0071822 280 0.030
response to chemical GO:0042221 356 0.030
cellular component assembly GO:0022607 293 0.029
cellular protein metabolic process GO:0044267 279 0.029
regulation of rna metabolic process GO:0051252 173 0.029
Yeast
cellular response to stress GO:0033554 162 0.029
Yeast
positive regulation of cellular process GO:0048522 332 0.029
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.028
Yeast
organic substance catabolic process GO:1901575 294 0.028
small molecule metabolic process GO:0044281 186 0.027
post embryonic organ development GO:0048569 336 0.027
macromolecule catabolic process GO:0009057 202 0.027
regulation of post embryonic development GO:0048580 260 0.027
protein complex biogenesis GO:0070271 186 0.027
cellular component biogenesis GO:0044085 297 0.026
cytoskeleton organization GO:0007010 339 0.026
cell migration GO:0016477 306 0.026
signal transduction GO:0007165 317 0.026
macromolecule modification GO:0043412 218 0.026
response to external stimulus GO:0009605 289 0.026
negative regulation of cellular metabolic process GO:0031324 95 0.026
Yeast
organelle assembly GO:0070925 214 0.026
regulation of multicellular organismal development GO:2000026 317 0.026
dna metabolic process GO:0006259 74 0.026
Yeast
localization of cell GO:0051674 313 0.025
regulation of nematode larval development GO:0061062 260 0.025
cellular component assembly involved in morphogenesis GO:0010927 183 0.025
negative regulation of developmental process GO:0051093 227 0.025
negative regulation of multicellular organismal process GO:0051241 236 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.025
Yeast
regulation of vulval development GO:0040028 248 0.024
negative regulation of nucleic acid templated transcription GO:1903507 53 0.024
Yeast
chromosome segregation GO:0007059 180 0.024
anatomical structure formation involved in morphogenesis GO:0048646 250 0.024
protein localization GO:0008104 205 0.024
chromosome organization GO:0051276 104 0.024
Yeast
regulation of cellular component organization GO:0051128 248 0.024
female gamete generation GO:0007292 254 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.023
Yeast
negative regulation of biosynthetic process GO:0009890 65 0.023
Yeast
negative regulation of cellular biosynthetic process GO:0031327 65 0.023
Yeast
protein catabolic process GO:0030163 162 0.023
secretion by cell GO:0032940 138 0.023
negative regulation of nematode larval development GO:0061064 208 0.023
regulation of organelle organization GO:0033043 164 0.023
cell motility GO:0048870 313 0.022
cellular protein complex assembly GO:0043623 178 0.022
macromolecular complex assembly GO:0065003 193 0.022
negative regulation of vulval development GO:0040027 206 0.022
cellular component movement GO:0006928 388 0.022
oogenesis GO:0048477 229 0.022
regulation of response to stimulus GO:0048583 243 0.022
sensory organ morphogenesis GO:0090596 2 0.021
protein complex assembly GO:0006461 186 0.021
protein modification process GO:0036211 207 0.021
regulation of localization GO:0032879 194 0.021
positive regulation of neurogenesis GO:0050769 4 0.021
nervous system development GO:0007399 253 0.021
cellular catabolic process GO:0044248 199 0.021
regulation of cell cycle GO:0051726 194 0.021
actin filament based process GO:0030029 191 0.021
dna repair GO:0006281 23 0.021
Yeast
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.021
Yeast
cellular macromolecular complex assembly GO:0034622 184 0.021
regulation of cytoplasmic transport GO:1903649 3 0.021
chromatin assembly or disassembly GO:0006333 1 0.021
Yeast
microtubule based process GO:0007017 182 0.020
meiotic chromosome segregation GO:0045132 139 0.020
organelle localization GO:0051640 127 0.020
muscle structure development GO:0061061 191 0.020
actomyosin structure organization GO:0031032 154 0.020
cellular protein modification process GO:0006464 207 0.019
positive regulation of cellular metabolic process GO:0031325 178 0.019
establishment of organelle localization GO:0051656 123 0.019
secretion GO:0046903 147 0.019
inductive cell migration GO:0040039 145 0.019
regulation of cell communication GO:0010646 176 0.019
posttranscriptional regulation of gene expression GO:0010608 166 0.019
membrane organization GO:0061024 135 0.019
actin cytoskeleton organization GO:0030036 184 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
negative regulation of post embryonic development GO:0048581 208 0.019
regulation of cell division GO:0051302 142 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.018
Yeast
negative regulation of rna biosynthetic process GO:1902679 53 0.018
Yeast
regulation of cellular ketone metabolic process GO:0010565 3 0.018
mitotic cell cycle process GO:1903047 194 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.018
positive regulation of metabolic process GO:0009893 187 0.018
myosin filament assembly GO:0031034 138 0.017
myofibril assembly GO:0030239 154 0.017
muscle cell differentiation GO:0042692 171 0.017
striated muscle myosin thick filament assembly GO:0071688 138 0.017
negative regulation of transcription dna templated GO:0045892 53 0.017
Yeast
myosin filament organization GO:0031033 138 0.017
phagocytosis GO:0006909 115 0.017
cuticle development GO:0042335 100 0.017
regulation of nuclear division GO:0051783 115 0.017
response to organic substance GO:0010033 131 0.017
phosphorus metabolic process GO:0006793 232 0.017
gene silencing by rna GO:0031047 143 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
posttranscriptional gene silencing GO:0016441 143 0.016
posttranscriptional gene silencing by rna GO:0035194 143 0.016
muscle cell development GO:0055001 158 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
cell projection organization GO:0030030 231 0.016
regulation of cell cycle process GO:0010564 145 0.016
oxoacid metabolic process GO:0043436 47 0.016
response to biotic stimulus GO:0009607 101 0.015
defense response to other organism GO:0098542 100 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
phagocytosis engulfment GO:0006911 98 0.015
response to abiotic stimulus GO:0009628 152 0.015
striated muscle cell development GO:0055002 157 0.015
defense response to bacterium GO:0042742 86 0.015
neurogenesis GO:0022008 236 0.015
response to other organism GO:0051707 101 0.015
regulation of meiotic cell cycle GO:0051445 136 0.015
cell proliferation GO:0008283 116 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.015
regulation of signaling GO:0023051 172 0.015
generation of neurons GO:0048699 235 0.015
organic acid metabolic process GO:0006082 47 0.015
striated muscle cell differentiation GO:0051146 158 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
cell morphogenesis GO:0000902 163 0.014
collagen and cuticulin based cuticle development GO:0040002 99 0.014
cell type specific apoptotic process GO:0097285 4 0.014
ribonucleoprotein complex assembly GO:0022618 4 0.014
rna interference GO:0016246 137 0.014
response to external biotic stimulus GO:0043207 101 0.014
mitotic nuclear division GO:0007067 89 0.014
neuron development GO:0048666 199 0.014
amine metabolic process GO:0009308 15 0.014
positive regulation of neuron differentiation GO:0045666 4 0.014
apoptotic cell clearance GO:0043277 111 0.014
engulfment of apoptotic cell GO:0043652 94 0.014
regulation of nucleocytoplasmic transport GO:0046822 3 0.014
neuron differentiation GO:0030182 217 0.014
neuromuscular junction development GO:0007528 2 0.013
protein oligomerization GO:0051259 4 0.013
single organism catabolic process GO:0044712 129 0.013
establishment of nucleus localization GO:0040023 55 0.013
negative regulation of rna metabolic process GO:0051253 53 0.013
Yeast
cellular amino acid metabolic process GO:0006520 15 0.013
regulation of lipid metabolic process GO:0019216 4 0.013
neuron projection development GO:0031175 187 0.013
membrane invagination GO:0010324 98 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.013
dauer larval development GO:0040024 92 0.013
cellular amine metabolic process GO:0044106 15 0.013
regulation of response to wounding GO:1903034 1 0.013
regulation of meiosis GO:0040020 94 0.013
cellular ketone metabolic process GO:0042180 14 0.012
regulation of signal transduction GO:0009966 135 0.012
axon development GO:0061564 163 0.012
regulation of cell proliferation GO:0042127 105 0.012
regeneration GO:0031099 4 0.012
organic substance transport GO:0071702 113 0.012
cellular response to chemical stimulus GO:0070887 129 0.012
cytokinesis GO:0000910 80 0.012
response to bacterium GO:0009617 86 0.012
nucleobase containing compound catabolic process GO:0034655 114 0.012
cell projection morphogenesis GO:0048858 148 0.012
single organism biosynthetic process GO:0044711 91 0.012
positive regulation of macromolecule metabolic process GO:0010604 149 0.012
heterocycle catabolic process GO:0046700 119 0.012
positive regulation of rna metabolic process GO:0051254 103 0.012
ribosome biogenesis GO:0042254 4 0.012
muscle tissue development GO:0060537 1 0.012
embryonic morphogenesis GO:0048598 152 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
phosphorylation GO:0016310 116 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.011
detection of external stimulus GO:0009581 4 0.011
regulation of organ morphogenesis GO:2000027 4 0.011
regulation of protein targeting GO:1903533 3 0.011
aromatic compound catabolic process GO:0019439 116 0.011
cellular response to organic substance GO:0071310 119 0.011
cell part morphogenesis GO:0032990 152 0.011
positive regulation of cellular biosynthetic process GO:0031328 109 0.011
nuclear migration GO:0007097 54 0.011
regulation of locomotion GO:0040012 161 0.011
epithelial tube morphogenesis GO:0060562 1 0.011
regulation of transport GO:0051049 91 0.010
organic cyclic compound catabolic process GO:1901361 119 0.010
peptidyl tyrosine phosphorylation GO:0018108 2 0.010
skeletal muscle organ development GO:0060538 3 0.010
cell cell signaling GO:0007267 118 0.010
chromatin organization GO:0006325 32 0.010
Yeast
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.010
cellular response to abiotic stimulus GO:0071214 4 0.010
intracellular transport GO:0046907 77 0.010
cellular response to topologically incorrect protein GO:0035967 76 0.010
positive regulation of cell migration GO:0030335 3 0.010
hormone transport GO:0009914 2 0.010
positive regulation of biosynthetic process GO:0009891 109 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
axonal fasciculation GO:0007413 79 0.010
system process GO:0003008 136 0.010

his-58 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023