Caenorhabditis elegans

24 known processes

unc-120 (CELE_D1081.2)

Protein UNC-120

unc-120 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.739
Mouse
organ development GO:0048513 1102 0.560
Human Mouse Fly
muscle tissue development GO:0060537 1 0.490
Mouse
embryo development GO:0009790 3052 0.479
anatomical structure formation involved in morphogenesis GO:0048646 250 0.462
Human Mouse
death GO:0016265 547 0.441
cell migration GO:0016477 306 0.422
Human Mouse
regulation of developmental process GO:0050793 684 0.391
Human Mouse
cell surface receptor signaling pathway GO:0007166 149 0.391
apoptotic process GO:0006915 478 0.329
taxis GO:0042330 128 0.325
embryo development ending in birth or egg hatching GO:0009792 2992 0.324
neuron projection morphogenesis GO:0048812 114 0.317
Mouse
developmental process involved in reproduction GO:0003006 1165 0.304
regulation of rna biosynthetic process GO:2001141 165 0.298
Human Mouse Fly
axon development GO:0061564 163 0.292
Mouse
negative regulation of biological process GO:0048519 567 0.286
Human Mouse
chemotaxis GO:0006935 120 0.268
cellular component movement GO:0006928 388 0.267
Human Mouse
cell part morphogenesis GO:0032990 152 0.261
Mouse
single organism organelle organization GO:1902589 501 0.240
Mouse
response to chemical GO:0042221 356 0.239
Human
sex differentiation GO:0007548 909 0.232
localization of cell GO:0051674 313 0.231
Human Mouse
post embryonic organ development GO:0048569 336 0.227
Fly
cell morphogenesis GO:0000902 163 0.218
Mouse
signal transduction GO:0007165 317 0.205
post embryonic development GO:0009791 2152 0.203
axonogenesis GO:0007409 102 0.197
Mouse
negative regulation of cellular process GO:0048523 239 0.190
Mouse
positive regulation of cellular process GO:0048522 332 0.180
Human Mouse Fly
cell motility GO:0048870 313 0.177
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 189 0.176
Human Mouse Fly
single organism signaling GO:0044700 401 0.171
Mouse
neuron projection development GO:0031175 187 0.168
Mouse
growth GO:0040007 562 0.160
Mouse
reproductive structure development GO:0048608 850 0.158
response to external stimulus GO:0009605 289 0.152
skeletal muscle organ development GO:0060538 3 0.151
signaling GO:0023052 401 0.151
Mouse
regulation of rna metabolic process GO:0051252 173 0.149
Human Mouse Fly
regulation of transcription dna templated GO:0006355 164 0.148
Human Mouse Fly
cellular component morphogenesis GO:0032989 318 0.147
Mouse
protein metabolic process GO:0019538 422 0.146
positive regulation of transcription dna templated GO:0045893 102 0.145
Human Mouse Fly
axon guidance GO:0007411 82 0.144
nervous system development GO:0007399 253 0.144
Mouse
striated muscle cell development GO:0055002 157 0.143
Mouse
multicellular organism reproduction GO:0032504 819 0.140
programmed cell death GO:0012501 500 0.135
gonad development GO:0008406 840 0.135
cell development GO:0048468 696 0.133
Mouse
oviposition GO:0018991 364 0.131
rna biosynthetic process GO:0032774 169 0.130
Human Mouse Fly
cell death GO:0008219 547 0.129
single organism transport GO:0044765 447 0.126
regulation of cell communication GO:0010646 176 0.125
Mouse
regulation of vulval development GO:0040028 248 0.124
negative regulation of developmental process GO:0051093 227 0.123
epithelial cell proliferation GO:0050673 1 0.121
multicellular organismal reproductive process GO:0048609 815 0.121
muscle attachment GO:0016203 3 0.121
actin filament based process GO:0030029 191 0.121
Mouse
positive regulation of gene expression GO:0010628 112 0.117
Human Mouse Fly
developmental growth GO:0048589 412 0.116
Mouse
reproductive system development GO:0061458 850 0.116
locomotion GO:0040011 1634 0.112
organ morphogenesis GO:0009887 67 0.112
Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.111
Human Mouse Fly
gene expression GO:0010467 412 0.111
Human Mouse Fly
behavior GO:0007610 527 0.109
Mouse Fly
integrin mediated signaling pathway GO:0007229 1 0.108
regulation of epithelial cell proliferation GO:0050678 1 0.104
multicellular organismal reproductive behavior GO:0033057 384 0.103
positive regulation of multicellular organismal process GO:0051240 417 0.102
Human Mouse
positive regulation of response to stimulus GO:0048584 55 0.101
multi organism behavior GO:0051705 389 0.100
cell fate commitment GO:0045165 139 0.100
vesicle mediated transport GO:0016192 852 0.099
macromolecule biosynthetic process GO:0009059 250 0.099
Human Mouse Fly
protein catabolic process GO:0030163 162 0.098
regulation of response to stimulus GO:0048583 243 0.098
body morphogenesis GO:0010171 620 0.097
regulation of metabolic process GO:0019222 478 0.097
Human Mouse Fly
nucleobase containing compound metabolic process GO:0006139 406 0.096
Human Mouse Fly
cellular biosynthetic process GO:0044249 315 0.096
Human Mouse Fly
regulation of cell cycle GO:0051726 194 0.094
female gamete generation GO:0007292 254 0.093
regulation of organelle organization GO:0033043 164 0.093
nucleic acid metabolic process GO:0090304 299 0.092
Human Mouse Fly
cytoskeleton organization GO:0007010 339 0.091
Mouse
positive regulation of developmental process GO:0051094 408 0.090
Human Mouse
regulation of nitrogen compound metabolic process GO:0051171 222 0.089
Human Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 149 0.087
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 421 0.087
Human Mouse Fly
development of primary sexual characteristics GO:0045137 840 0.087
negative regulation of vulval development GO:0040027 206 0.086
cellular component biogenesis GO:0044085 297 0.086
Human Mouse
muscle structure development GO:0061061 191 0.085
Human Mouse
oogenesis GO:0048477 229 0.085
muscle organ morphogenesis GO:0048644 4 0.084
muscle cell development GO:0055001 158 0.084
Mouse
endocytosis GO:0006897 819 0.084
genitalia development GO:0048806 741 0.083
regulation of gene expression GO:0010468 366 0.082
Human Mouse Fly
regulation of post embryonic development GO:0048580 260 0.079
multi organism reproductive process GO:0044703 867 0.078
multi organism reproductive behavior GO:0044705 387 0.078
positive regulation of rna biosynthetic process GO:1902680 102 0.075
Human Mouse Fly
cell cycle GO:0007049 526 0.074
cell morphogenesis involved in differentiation GO:0000904 112 0.074
Mouse
myofibril assembly GO:0030239 154 0.074
Mouse
organic substance biosynthetic process GO:1901576 323 0.073
Human Mouse Fly
biosynthetic process GO:0009058 323 0.073
Human Mouse Fly
actin cytoskeleton organization GO:0030036 184 0.072
Mouse
transport GO:0006810 1093 0.072
epithelial tube morphogenesis GO:0060562 1 0.071
Mouse Fly
positive regulation of rna metabolic process GO:0051254 103 0.070
Human Mouse Fly
response to wounding GO:0009611 4 0.070
Mouse
single organism localization GO:1902578 518 0.070
positive regulation of macromolecule metabolic process GO:0010604 149 0.070
Human Mouse Fly
tube morphogenesis GO:0035239 79 0.069
Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.068
Human Mouse Fly
transcription dna templated GO:0006351 168 0.068
Human Mouse Fly
organelle organization GO:0006996 783 0.066
Mouse
regulation of cell motility GO:2000145 57 0.066
negative regulation of nematode larval development GO:0061064 208 0.065
tissue morphogenesis GO:0048729 65 0.065
Mouse Fly
regulation of biological quality GO:0065008 741 0.064
Mouse
regulation of locomotion GO:0040012 161 0.063
regulation of nematode larval development GO:0061062 260 0.062
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.060
regulation of multicellular organismal development GO:2000026 317 0.060
Mouse
macromolecule localization GO:0033036 771 0.060
positive regulation of biosynthetic process GO:0009891 109 0.059
Human Mouse Fly
aromatic compound biosynthetic process GO:0019438 192 0.059
Human Mouse Fly
multi multicellular organism process GO:0044706 390 0.058
cell projection morphogenesis GO:0048858 148 0.058
Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.058
Human
hermaphrodite genitalia development GO:0040035 734 0.058
regulation of growth GO:0040008 409 0.057
Mouse
macromolecular complex subunit organization GO:0043933 320 0.057
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.056
Human Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.055
Human Mouse Fly
germ cell development GO:0007281 351 0.054
regulation of cell migration GO:0030334 55 0.054
neurogenesis GO:0022008 236 0.054
Mouse
lipid storage GO:0019915 565 0.053
vulval development GO:0040025 333 0.053
regulation of cellular component organization GO:0051128 248 0.053
Human Mouse
cellular response to chemical stimulus GO:0070887 129 0.052
cellular response to organic substance GO:0071310 119 0.052
muscle cell differentiation GO:0042692 171 0.052
Human Mouse
rna metabolic process GO:0016070 228 0.052
Human Mouse Fly
reproductive behavior GO:0019098 387 0.052
organelle assembly GO:0070925 214 0.052
Mouse
maintenance of location GO:0051235 580 0.052
cellular response to stress GO:0033554 162 0.051
Human
lipid localization GO:0010876 573 0.050
regulation of developmental growth GO:0048638 389 0.049
Mouse
gamete generation GO:0007276 461 0.049
positive regulation of cellular biosynthetic process GO:0031328 109 0.049
Human Mouse Fly
aging GO:0007568 812 0.049
Human
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.048
Human Mouse Fly
establishment of localization GO:0051234 1171 0.048
organic cyclic compound biosynthetic process GO:1901362 195 0.048
Human Mouse Fly
protein complex assembly GO:0006461 186 0.047
Human
generation of neurons GO:0048699 235 0.046
Mouse
protein complex biogenesis GO:0070271 186 0.046
Human
cell projection organization GO:0030030 231 0.044
Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.043
Human Mouse Fly
striated muscle cell differentiation GO:0051146 158 0.043
Mouse
cellular protein metabolic process GO:0044267 279 0.043
nucleic acid templated transcription GO:0097659 169 0.043
Human Mouse Fly
regulation of cell proliferation GO:0042127 105 0.042
regulation of cellular component movement GO:0051270 62 0.042
neuron projection guidance GO:0097485 82 0.042
multicellular organismal aging GO:0010259 812 0.041
regulation of nucleic acid templated transcription GO:1903506 165 0.041
Human Mouse Fly
sexual reproduction GO:0019953 546 0.041
regulation of mitotic cell cycle GO:0007346 76 0.040
single organism reproductive process GO:0044702 1196 0.040
neuron development GO:0048666 199 0.039
Mouse
determination of adult lifespan GO:0008340 812 0.039
cellular localization GO:0051641 360 0.039
cell cycle process GO:0022402 482 0.039
positive regulation of locomotion GO:0040017 42 0.039
phagocytosis GO:0006909 115 0.039
regulation of multicellular organismal process GO:0051239 726 0.038
Human Mouse
neuron differentiation GO:0030182 217 0.037
Mouse
head development GO:0060322 1 0.036
Mouse
digestive tract morphogenesis GO:0048546 76 0.036
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.036
Human Mouse Fly
regulation of cellular metabolic process GO:0031323 305 0.036
Human Mouse Fly
cell matrix adhesion GO:0007160 1 0.035
Mouse
positive regulation of developmental growth GO:0048639 354 0.035
Mouse
multicellular organism growth GO:0035264 385 0.035
mesodermal cell migration GO:0008078 9 0.035
epithelium development GO:0060429 68 0.035
Mouse Fly
cellular component assembly involved in morphogenesis GO:0010927 183 0.034
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 50 0.034
regulation of primary metabolic process GO:0080090 292 0.034
Human Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.034
Human Mouse Fly
male sex differentiation GO:0046661 86 0.034
positive regulation of multicellular organism growth GO:0040018 352 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.033
Human Mouse Fly
positive regulation of growth GO:0045927 369 0.033
Mouse
regulation of localization GO:0032879 194 0.033
cell division GO:0051301 262 0.033
regulation of biosynthetic process GO:0009889 189 0.033
Human Mouse Fly
wnt signaling pathway GO:0016055 27 0.033
tube development GO:0035295 126 0.033
Mouse Fly
regulation of cell differentiation GO:0045595 81 0.033
Human Mouse
negative regulation of gene expression GO:0010629 217 0.031
positive regulation of metabolic process GO:0009893 187 0.031
Human Mouse Fly
positive regulation of signal transduction GO:0009967 40 0.031
dorsal ventral axon guidance GO:0033563 19 0.031
cellular protein complex assembly GO:0043623 178 0.030
heterocycle biosynthetic process GO:0018130 187 0.030
Human Mouse Fly
regulation of cell cycle process GO:0010564 145 0.030
regulation of cellular biosynthetic process GO:0031326 189 0.029
Human Mouse Fly
regulation of multicellular organism growth GO:0040014 373 0.029
establishment or maintenance of cell polarity GO:0007163 63 0.029
regulation of signaling GO:0023051 172 0.029
Mouse
negative regulation of metabolic process GO:0009892 240 0.029
cellular protein modification process GO:0006464 207 0.029
negative regulation of macromolecule metabolic process GO:0010605 229 0.029
tissue development GO:0009888 112 0.029
Mouse Fly
canonical wnt signaling pathway GO:0060070 3 0.029
establishment of localization in cell GO:0051649 318 0.028
receptor mediated endocytosis GO:0006898 715 0.028
endodermal cell differentiation GO:0035987 18 0.028
catabolic process GO:0009056 318 0.027
regulation of signal transduction GO:0009966 135 0.026
protein modification process GO:0036211 207 0.026
defense response to other organism GO:0098542 100 0.026
regulation of cytoskeleton organization GO:0051493 41 0.025
negative regulation of post embryonic development GO:0048581 208 0.025
cuticle development GO:0042335 100 0.025
positive regulation of cell migration GO:0030335 3 0.023
apoptotic cell clearance GO:0043277 111 0.023
muscle organ development GO:0007517 26 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
Human Mouse Fly
sensory organ morphogenesis GO:0090596 2 0.022
cell type specific apoptotic process GO:0097285 4 0.022
posttranscriptional regulation of gene expression GO:0010608 166 0.022
cellular component assembly GO:0022607 293 0.022
Human Mouse
response to organic substance GO:0010033 131 0.022
Human
organic substance catabolic process GO:1901575 294 0.021
secretion GO:0046903 147 0.021
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.021
myosin filament assembly GO:0031034 138 0.021
system process GO:0003008 136 0.021
Human Mouse Fly
positive regulation of signaling GO:0023056 66 0.020
protein complex subunit organization GO:0071822 280 0.020
Human Mouse
negative regulation of biosynthetic process GO:0009890 65 0.020
actomyosin structure organization GO:0031032 154 0.020
Mouse
phosphorylation GO:0016310 116 0.020
macromolecular complex assembly GO:0065003 193 0.020
Human
regeneration GO:0031099 4 0.020
positive regulation of epithelial cell proliferation GO:0050679 1 0.020
striated muscle myosin thick filament assembly GO:0071688 138 0.020
phosphate containing compound metabolic process GO:0006796 232 0.019
positive regulation of neurogenesis GO:0050769 4 0.019
Mouse
single organism biosynthetic process GO:0044711 91 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
regionalization GO:0003002 31 0.019
Mouse
negative regulation of response to stimulus GO:0048585 73 0.019
cellular nitrogen compound biosynthetic process GO:0044271 192 0.019
Human Mouse Fly
cell proliferation GO:0008283 116 0.018
protein localization GO:0008104 205 0.018
regulation of cellular component biogenesis GO:0044087 26 0.018
Human Mouse
macromolecule modification GO:0043412 218 0.018
cell junction organization GO:0034330 18 0.018
Mouse
myosin filament organization GO:0031033 138 0.017
organelle fission GO:0048285 363 0.017
negative regulation of cell communication GO:0010648 61 0.017
Mouse
muscle system process GO:0003012 43 0.017
Human
response to acid chemical GO:0001101 4 0.017
cell cell signaling GO:0007267 118 0.017
Mouse
cell growth GO:0016049 44 0.017
Mouse
cell projection assembly GO:0030031 35 0.017
Mouse
collagen and cuticulin based cuticle development GO:0040002 99 0.017
negative regulation of cellular metabolic process GO:0031324 95 0.017
regulation of cell death GO:0010941 65 0.016
inductive cell migration GO:0040039 145 0.016
regulation of gene expression epigenetic GO:0040029 163 0.016
chromosome organization GO:0051276 104 0.016
backward locomotion GO:0043057 11 0.016
macromolecule catabolic process GO:0009057 202 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
Human
organelle localization GO:0051640 127 0.016
regulation of response to wounding GO:1903034 1 0.016
negative regulation of signal transduction GO:0009968 60 0.016
regulation of protein metabolic process GO:0051246 81 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
negative regulation of cell cycle GO:0045786 53 0.015
negative regulation of nucleic acid templated transcription GO:1903507 53 0.015
digestive tract development GO:0048565 122 0.015
Mouse
male anatomical structure morphogenesis GO:0090598 78 0.015
response to external biotic stimulus GO:0043207 101 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.014
regulation of cell development GO:0060284 49 0.014
Mouse
intracellular signal transduction GO:0035556 96 0.014
innate immune response GO:0045087 190 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.014
regulation of canonical wnt signaling pathway GO:0060828 1 0.014
bmp signaling pathway GO:0030509 3 0.014
spindle localization GO:0051653 51 0.014
neuron recognition GO:0008038 83 0.014
regulation of apoptotic process GO:0042981 36 0.014
nitrogen compound transport GO:0071705 49 0.013
negative regulation of neuron differentiation GO:0045665 4 0.013
ovulation GO:0030728 33 0.013
positive regulation of cell cycle GO:0045787 55 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
pattern specification process GO:0007389 59 0.013
Mouse
small molecule metabolic process GO:0044281 186 0.013
short term memory GO:0007614 2 0.013
Fly
mitotic cell cycle process GO:1903047 194 0.013
regulation of jun kinase activity GO:0043506 3 0.013
negative regulation of locomotion GO:0040013 21 0.013
regulation of cell division GO:0051302 142 0.013
establishment of organelle localization GO:0051656 123 0.013
negative regulation of neurogenesis GO:0050768 4 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
epidermis development GO:0008544 24 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
pigment metabolic process GO:0042440 2 0.012
regulation of programmed cell death GO:0043067 50 0.012
stress activated mapk cascade GO:0051403 10 0.012
regulation of actin filament based process GO:0032970 22 0.012
negative regulation of transcription dna templated GO:0045892 53 0.012
cellular macromolecular complex assembly GO:0034622 184 0.012
establishment of mitotic spindle localization GO:0040001 41 0.012
digestive system development GO:0055123 122 0.012
Mouse
single organism cellular localization GO:1902580 72 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
negative regulation of cellular biosynthetic process GO:0031327 65 0.011
organic substance transport GO:0071702 113 0.011
feeding behavior GO:0007631 70 0.011
response to biotic stimulus GO:0009607 101 0.011
response to abiotic stimulus GO:0009628 152 0.011
Human
establishment of vesicle localization GO:0051650 23 0.011
skeletal muscle thin filament assembly GO:0030240 3 0.011
regulation of protein localization GO:0032880 50 0.011
stem cell differentiation GO:0048863 7 0.011
Human Mouse
skin development GO:0043588 24 0.011
Mouse
regulation of meiotic cell cycle GO:0051445 136 0.011
axonal defasciculation GO:0007414 1 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.010
Human Mouse Fly
secretion by cell GO:0032940 138 0.010
regulation of anatomical structure morphogenesis GO:0022603 51 0.010
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.010
Mouse
regulation of cellular component size GO:0032535 40 0.010
Mouse
establishment of cell polarity GO:0030010 46 0.010
specification of axis polarity GO:0065001 13 0.010
neuron apoptotic process GO:0051402 4 0.010
actin filament organization GO:0007015 21 0.010
Mouse

unc-120 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.024
muscular disease DOID:0080000 0 0.024
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.024
muscle tissue disease DOID:66 0 0.024
nervous system disease DOID:863 0 0.011
heart disease DOID:114 0 0.011
cardiovascular system disease DOID:1287 0 0.011