Caenorhabditis elegans

24 known processes

unc-120 (CELE_D1081.2)

Protein UNC-120

unc-120 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.739
Mouse
organ development GO:0048513 1102 0.560
Human Mouse Fly
muscle tissue development GO:0060537 1 0.490
Mouse
embryo development GO:0009790 3052 0.479
anatomical structure formation involved in morphogenesis GO:0048646 250 0.462
Human Mouse
death GO:0016265 547 0.441
cell migration GO:0016477 306 0.422
Human Mouse
regulation of developmental process GO:0050793 684 0.391
Human Mouse
cell surface receptor signaling pathway GO:0007166 149 0.391
apoptotic process GO:0006915 478 0.329
taxis GO:0042330 128 0.325
embryo development ending in birth or egg hatching GO:0009792 2992 0.324
neuron projection morphogenesis GO:0048812 114 0.317
Mouse
developmental process involved in reproduction GO:0003006 1165 0.304
regulation of rna biosynthetic process GO:2001141 165 0.298
Human Mouse Fly
axon development GO:0061564 163 0.292
Mouse
negative regulation of biological process GO:0048519 567 0.286
Human Mouse
chemotaxis GO:0006935 120 0.268
cellular component movement GO:0006928 388 0.267
Human Mouse
cell part morphogenesis GO:0032990 152 0.261
Mouse
single organism organelle organization GO:1902589 501 0.240
Mouse
response to chemical GO:0042221 356 0.239
Human
sex differentiation GO:0007548 909 0.232
localization of cell GO:0051674 313 0.231
Human Mouse
post embryonic organ development GO:0048569 336 0.227
Fly
cell morphogenesis GO:0000902 163 0.218
Mouse
signal transduction GO:0007165 317 0.205
post embryonic development GO:0009791 2152 0.203
axonogenesis GO:0007409 102 0.197
Mouse
negative regulation of cellular process GO:0048523 239 0.190
Mouse
positive regulation of cellular process GO:0048522 332 0.180
Human Mouse Fly
cell motility GO:0048870 313 0.177
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 189 0.176
Human Mouse Fly
single organism signaling GO:0044700 401 0.171
Mouse
neuron projection development GO:0031175 187 0.168
Mouse
growth GO:0040007 562 0.160
Mouse
reproductive structure development GO:0048608 850 0.158
response to external stimulus GO:0009605 289 0.152
skeletal muscle organ development GO:0060538 3 0.151
signaling GO:0023052 401 0.151
Mouse
regulation of rna metabolic process GO:0051252 173 0.149
Human Mouse Fly
regulation of transcription dna templated GO:0006355 164 0.148
Human Mouse Fly
cellular component morphogenesis GO:0032989 318 0.147
Mouse
protein metabolic process GO:0019538 422 0.146
positive regulation of transcription dna templated GO:0045893 102 0.145
Human Mouse Fly
axon guidance GO:0007411 82 0.144
nervous system development GO:0007399 253 0.144
Mouse
striated muscle cell development GO:0055002 157 0.143
Mouse
multicellular organism reproduction GO:0032504 819 0.140
programmed cell death GO:0012501 500 0.135
gonad development GO:0008406 840 0.135
cell development GO:0048468 696 0.133
Mouse
oviposition GO:0018991 364 0.131
rna biosynthetic process GO:0032774 169 0.130
Human Mouse Fly
cell death GO:0008219 547 0.129
single organism transport GO:0044765 447 0.126
regulation of cell communication GO:0010646 176 0.125
Mouse
regulation of vulval development GO:0040028 248 0.124
negative regulation of developmental process GO:0051093 227 0.123
epithelial cell proliferation GO:0050673 1 0.121
multicellular organismal reproductive process GO:0048609 815 0.121
muscle attachment GO:0016203 3 0.121
actin filament based process GO:0030029 191 0.121
Mouse
positive regulation of gene expression GO:0010628 112 0.117
Human Mouse Fly
developmental growth GO:0048589 412 0.116
Mouse
reproductive system development GO:0061458 850 0.116
locomotion GO:0040011 1634 0.112
organ morphogenesis GO:0009887 67 0.112
Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.111
Human Mouse Fly
gene expression GO:0010467 412 0.111
Human Mouse Fly
behavior GO:0007610 527 0.109
Mouse Fly
integrin mediated signaling pathway GO:0007229 1 0.108
regulation of epithelial cell proliferation GO:0050678 1 0.104
multicellular organismal reproductive behavior GO:0033057 384 0.103
positive regulation of multicellular organismal process GO:0051240 417 0.102
Human Mouse
positive regulation of response to stimulus GO:0048584 55 0.101
multi organism behavior GO:0051705 389 0.100
cell fate commitment GO:0045165 139 0.100
vesicle mediated transport GO:0016192 852 0.099
macromolecule biosynthetic process GO:0009059 250 0.099
Human Mouse Fly
protein catabolic process GO:0030163 162 0.098
regulation of response to stimulus GO:0048583 243 0.098
body morphogenesis GO:0010171 620 0.097
regulation of metabolic process GO:0019222 478 0.097
Human Mouse Fly
nucleobase containing compound metabolic process GO:0006139 406 0.096
Human Mouse Fly
cellular biosynthetic process GO:0044249 315 0.096
Human Mouse Fly
regulation of cell cycle GO:0051726 194 0.094
female gamete generation GO:0007292 254 0.093
regulation of organelle organization GO:0033043 164 0.093
nucleic acid metabolic process GO:0090304 299 0.092
Human Mouse Fly
cytoskeleton organization GO:0007010 339 0.091
Mouse
positive regulation of developmental process GO:0051094 408 0.090
Human Mouse
regulation of nitrogen compound metabolic process GO:0051171 222 0.089
Human Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 149 0.087
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 421 0.087
Human Mouse Fly
development of primary sexual characteristics GO:0045137 840 0.087
negative regulation of vulval development GO:0040027 206 0.086
cellular component biogenesis GO:0044085 297 0.086
Human Mouse
muscle structure development GO:0061061 191 0.085
Human Mouse
oogenesis GO:0048477 229 0.085
muscle organ morphogenesis GO:0048644 4 0.084
muscle cell development GO:0055001 158 0.084
Mouse
endocytosis GO:0006897 819 0.084
genitalia development GO:0048806 741 0.083
regulation of gene expression GO:0010468 366 0.082
Human Mouse Fly
regulation of post embryonic development GO:0048580 260 0.079
multi organism reproductive process GO:0044703 867 0.078
multi organism reproductive behavior GO:0044705 387 0.078
positive regulation of rna biosynthetic process GO:1902680 102 0.075
Human Mouse Fly
cell cycle GO:0007049 526 0.074
cell morphogenesis involved in differentiation GO:0000904 112 0.074
Mouse
myofibril assembly GO:0030239 154 0.074
Mouse
organic substance biosynthetic process GO:1901576 323 0.073
Human Mouse Fly
biosynthetic process GO:0009058 323 0.073
Human Mouse Fly
actin cytoskeleton organization GO:0030036 184 0.072
Mouse
transport GO:0006810 1093 0.072
epithelial tube morphogenesis GO:0060562 1 0.071
Mouse Fly
positive regulation of rna metabolic process GO:0051254 103 0.070
Human Mouse Fly
response to wounding GO:0009611 4 0.070
Mouse
single organism localization GO:1902578 518 0.070
positive regulation of macromolecule metabolic process GO:0010604 149 0.070
Human Mouse Fly
tube morphogenesis GO:0035239 79 0.069
Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.068
Human Mouse Fly
transcription dna templated GO:0006351 168 0.068
Human Mouse Fly
organelle organization GO:0006996 783 0.066
Mouse
regulation of cell motility GO:2000145 57 0.066
negative regulation of nematode larval development GO:0061064 208 0.065
tissue morphogenesis GO:0048729 65 0.065
Mouse Fly
regulation of biological quality GO:0065008 741 0.064
Mouse
regulation of locomotion GO:0040012 161 0.063
regulation of nematode larval development GO:0061062 260 0.062
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.060
regulation of multicellular organismal development GO:2000026 317 0.060
Mouse
macromolecule localization GO:0033036 771 0.060
positive regulation of biosynthetic process GO:0009891 109 0.059
Human Mouse Fly
aromatic compound biosynthetic process GO:0019438 192 0.059
Human Mouse Fly
multi multicellular organism process GO:0044706 390 0.058
cell projection morphogenesis GO:0048858 148 0.058
Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.058
Human
hermaphrodite genitalia development GO:0040035 734 0.058
regulation of growth GO:0040008 409 0.057
Mouse
macromolecular complex subunit organization GO:0043933 320 0.057
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.056
Human Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.055
Human Mouse Fly
germ cell development GO:0007281 351 0.054
regulation of cell migration GO:0030334 55 0.054
neurogenesis GO:0022008 236 0.054
Mouse
lipid storage GO:0019915 565 0.053
vulval development GO:0040025 333 0.053
regulation of cellular component organization GO:0051128 248 0.053
Human Mouse
cellular response to chemical stimulus GO:0070887 129 0.052
cellular response to organic substance GO:0071310 119 0.052
muscle cell differentiation GO:0042692 171 0.052
Human Mouse
rna metabolic process GO:0016070 228 0.052
Human Mouse Fly
reproductive behavior GO:0019098 387 0.052
organelle assembly GO:0070925 214 0.052
Mouse
maintenance of location GO:0051235 580 0.052
cellular response to stress GO:0033554 162 0.051
Human
lipid localization GO:0010876 573 0.050
regulation of developmental growth GO:0048638 389 0.049
Mouse
gamete generation GO:0007276 461 0.049
positive regulation of cellular biosynthetic process GO:0031328 109 0.049
Human Mouse Fly
aging GO:0007568 812 0.049
Human
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.048
Human Mouse Fly
establishment of localization GO:0051234 1171 0.048
organic cyclic compound biosynthetic process GO:1901362 195 0.048
Human Mouse Fly
protein complex assembly GO:0006461 186 0.047
Human
generation of neurons GO:0048699 235 0.046
Mouse
protein complex biogenesis GO:0070271 186 0.046
Human
cell projection organization GO:0030030 231 0.044
Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.043
Human Mouse Fly
striated muscle cell differentiation GO:0051146 158 0.043
Mouse
cellular protein metabolic process GO:0044267 279 0.043
nucleic acid templated transcription GO:0097659 169 0.043
Human Mouse Fly
regulation of cell proliferation GO:0042127 105 0.042
regulation of cellular component movement GO:0051270 62 0.042
neuron projection guidance GO:0097485 82 0.042
multicellular organismal aging GO:0010259 812 0.041
regulation of nucleic acid templated transcription GO:1903506 165 0.041
Human Mouse Fly
sexual reproduction GO:0019953 546 0.041
regulation of mitotic cell cycle GO:0007346 76 0.040
single organism reproductive process GO:0044702 1196 0.040
neuron development GO:0048666 199 0.039
Mouse
determination of adult lifespan GO:0008340 812 0.039
cellular localization GO:0051641 360 0.039
cell cycle process GO:0022402 482 0.039
positive regulation of locomotion GO:0040017 42 0.039
phagocytosis GO:0006909 115 0.039
regulation of multicellular organismal process GO:0051239 726 0.038
Human Mouse
neuron differentiation GO:0030182 217 0.037
Mouse
head development GO:0060322 1 0.036
Mouse
digestive tract morphogenesis GO:0048546 76 0.036
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.036
Human Mouse Fly
regulation of cellular metabolic process GO:0031323 305 0.036
Human Mouse Fly
cell matrix adhesion GO:0007160 1 0.035
Mouse
positive regulation of developmental growth GO:0048639 354 0.035
Mouse
multicellular organism growth GO:0035264 385 0.035
mesodermal cell migration GO:0008078 9 0.035
epithelium development GO:0060429 68 0.035
Mouse Fly
cellular component assembly involved in morphogenesis GO:0010927 183 0.034
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 50 0.034
regulation of primary metabolic process GO:0080090 292 0.034
Human Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.034
Human Mouse Fly
male sex differentiation GO:0046661 86 0.034
positive regulation of multicellular organism growth GO:0040018 352 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.033
Human Mouse Fly
positive regulation of growth GO:0045927 369 0.033
Mouse
regulation of localization GO:0032879 194 0.033
cell division GO:0051301 262 0.033
regulation of biosynthetic process GO:0009889 189 0.033
Human Mouse Fly
wnt signaling pathway GO:0016055 27 0.033
tube development GO:0035295 126 0.033
Mouse Fly
regulation of cell differentiation GO:0045595 81 0.033
Human Mouse
negative regulation of gene expression GO:0010629 217 0.031
positive regulation of metabolic process GO:0009893 187 0.031
Human Mouse Fly
positive regulation of signal transduction GO:0009967 40 0.031
dorsal ventral axon guidance GO:0033563 19 0.031
cellular protein complex assembly GO:0043623 178 0.030
heterocycle biosynthetic process GO:0018130 187 0.030
Human Mouse Fly
regulation of cell cycle process GO:0010564 145 0.030
regulation of cellular biosynthetic process GO:0031326 189 0.029
Human Mouse Fly
regulation of multicellular organism growth GO:0040014 373 0.029
establishment or maintenance of cell polarity GO:0007163 63 0.029
regulation of signaling GO:0023051 172 0.029
Mouse
negative regulation of metabolic process GO:0009892 240 0.029
cellular protein modification process GO:0006464 207 0.029
negative regulation of macromolecule metabolic process GO:0010605 229 0.029
tissue development GO:0009888 112 0.029
Mouse Fly
canonical wnt signaling pathway GO:0060070 3 0.029
establishment of localization in cell GO:0051649 318 0.028
receptor mediated endocytosis GO:0006898 715 0.028
endodermal cell differentiation GO:0035987 18 0.028
catabolic process GO:0009056 318 0.027
regulation of signal transduction GO:0009966 135 0.026
protein modification process GO:0036211 207 0.026
defense response to other organism GO:0098542 100 0.026
regulation of cytoskeleton organization GO:0051493 41 0.025
negative regulation of post embryonic development GO:0048581 208 0.025
cuticle development GO:0042335 100 0.025
positive regulation of cell migration GO:0030335 3 0.023
apoptotic cell clearance GO:0043277 111 0.023
muscle organ development GO:0007517 26 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
Human Mouse Fly
sensory organ morphogenesis GO:0090596 2 0.022
cell type specific apoptotic process GO:0097285 4 0.022
posttranscriptional regulation of gene expression GO:0010608 166 0.022
cellular component assembly GO:0022607 293 0.022
Human Mouse
response to organic substance GO:0010033 131 0.022
Human
organic substance catabolic process GO:1901575 294 0.021
secretion GO:0046903 147 0.021
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.021
myosin filament assembly GO:0031034 138 0.021
system process GO:0003008 136 0.021
Human Mouse Fly
positive regulation of signaling GO:0023056 66 0.020
protein complex subunit organization GO:0071822 280 0.020
Human Mouse
negative regulation of biosynthetic process GO:0009890 65 0.020
actomyosin structure organization GO:0031032 154 0.020
Mouse
phosphorylation GO:0016310 116 0.020
macromolecular complex assembly GO:0065003 193 0.020
Human
regeneration GO:0031099 4 0.020
positive regulation of epithelial cell proliferation GO:0050679 1 0.020
striated muscle myosin thick filament assembly GO:0071688 138 0.020
phosphate containing compound metabolic process GO:0006796 232 0.019
positive regulation of neurogenesis GO:0050769 4 0.019
Mouse
single organism biosynthetic process GO:0044711 91 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
regionalization GO:0003002 31 0.019
Mouse
negative regulation of response to stimulus GO:0048585 73 0.019
cellular nitrogen compound biosynthetic process GO:0044271 192 0.019
Human Mouse Fly
cell proliferation GO:0008283 116 0.018
protein localization GO:0008104 205 0.018
regulation of cellular component biogenesis GO:0044087 26 0.018
Human Mouse
macromolecule modification GO:0043412 218 0.018
cell junction organization GO:0034330 18 0.018
Mouse
myosin filament organization GO:0031033 138 0.017
organelle fission GO:0048285 363 0.017
negative regulation of cell communication GO:0010648 61 0.017
Mouse
muscle system process GO:0003012 43 0.017
Human
response to acid chemical GO:0001101 4 0.017
cell cell signaling GO:0007267 118 0.017
Mouse
cell growth GO:0016049 44 0.017
Mouse
cell projection assembly GO:0030031 35 0.017
Mouse
collagen and cuticulin based cuticle development GO:0040002 99 0.017
negative regulation of cellular metabolic process GO:0031324 95 0.017
regulation of cell death GO:0010941 65 0.016
inductive cell migration GO:0040039 145 0.016
regulation of gene expression epigenetic GO:0040029 163 0.016
chromosome organization GO:0051276 104 0.016
backward locomotion GO:0043057 11 0.016
macromolecule catabolic process GO:0009057 202 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
Human
organelle localization GO:0051640 127 0.016
regulation of response to wounding GO:1903034 1 0.016
negative regulation of signal transduction GO:0009968 60 0.016
regulation of protein metabolic process GO:0051246 81 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
negative regulation of cell cycle GO:0045786 53 0.015
negative regulation of nucleic acid templated transcription GO:1903507 53 0.015
digestive tract development GO:0048565 122 0.015
Mouse
male anatomical structure morphogenesis GO:0090598 78 0.015
response to external biotic stimulus GO:0043207 101 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.014
regulation of cell development GO:0060284 49 0.014
Mouse
intracellular signal transduction GO:0035556 96 0.014
innate immune response GO:0045087 190 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.014
regulation of canonical wnt signaling pathway GO:0060828 1 0.014
bmp signaling pathway GO:0030509 3 0.014
spindle localization GO:0051653 51 0.014
neuron recognition GO:0008038 83 0.014
regulation of apoptotic process GO:0042981 36 0.014
nitrogen compound transport GO:0071705 49 0.013
negative regulation of neuron differentiation GO:0045665 4 0.013
ovulation GO:0030728 33 0.013
positive regulation of cell cycle GO:0045787 55 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
pattern specification process GO:0007389 59 0.013
Mouse
small molecule metabolic process GO:0044281 186 0.013
short term memory GO:0007614 2 0.013
Fly
mitotic cell cycle process GO:1903047 194 0.013
regulation of jun kinase activity GO:0043506 3 0.013
negative regulation of locomotion GO:0040013 21 0.013
regulation of cell division GO:0051302 142 0.013
establishment of organelle localization GO:0051656 123 0.013
negative regulation of neurogenesis GO:0050768 4 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
epidermis development GO:0008544 24 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
pigment metabolic process GO:0042440 2 0.012
regulation of programmed cell death GO:0043067 50 0.012
stress activated mapk cascade GO:0051403 10 0.012
regulation of actin filament based process GO:0032970 22 0.012
negative regulation of transcription dna templated GO:0045892 53 0.012
cellular macromolecular complex assembly GO:0034622 184 0.012
establishment of mitotic spindle localization GO:0040001 41 0.012
digestive system development GO:0055123 122 0.012
Mouse
single organism cellular localization GO:1902580 72 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
negative regulation of cellular biosynthetic process GO:0031327 65 0.011
organic substance transport GO:0071702 113 0.011
feeding behavior GO:0007631 70 0.011
response to biotic stimulus GO:0009607 101 0.011
response to abiotic stimulus GO:0009628 152 0.011
Human
establishment of vesicle localization GO:0051650 23 0.011
skeletal muscle thin filament assembly GO:0030240 3 0.011
regulation of protein localization GO:0032880 50 0.011
stem cell differentiation GO:0048863 7 0.011
Human Mouse
skin development GO:0043588 24 0.011
Mouse
regulation of meiotic cell cycle GO:0051445 136 0.011
axonal defasciculation GO:0007414 1 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.010
Human Mouse Fly
secretion by cell GO:0032940 138 0.010
regulation of anatomical structure morphogenesis GO:0022603 51 0.010
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.010
Mouse
regulation of cellular component size GO:0032535 40 0.010
Mouse
establishment of cell polarity GO:0030010 46 0.010
specification of axis polarity GO:0065001 13 0.010
neuron apoptotic process GO:0051402 4 0.010
actin filament organization GO:0007015 21 0.010
Mouse

unc-120 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
muscle tissue disease DOID:66 0 0.024
myopathy DOID:423 0 0.024
muscular disease DOID:0080000 0 0.024
musculoskeletal system disease DOID:17 0 0.024
nervous system disease DOID:863 0 0.011
cardiovascular system disease DOID:1287 0 0.011
heart disease DOID:114 0 0.011