Caenorhabditis elegans

23 known processes

unc-49 (CELE_T21C12.1)

Protein UNC-49

unc-49 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.660
locomotion GO:0040011 1634 0.473
embryo development ending in birth or egg hatching GO:0009792 2992 0.436
post embryonic development GO:0009791 2152 0.411
establishment of localization GO:0051234 1171 0.405
transport GO:0006810 1093 0.358
multicellular organism growth GO:0035264 385 0.329
multicellular organism reproduction GO:0032504 819 0.217
regulation of developmental process GO:0050793 684 0.194
regulation of signaling GO:0023051 172 0.185
ion transport GO:0006811 113 0.182
multicellular organismal reproductive process GO:0048609 815 0.181
signaling GO:0023052 401 0.161
developmental process involved in reproduction GO:0003006 1165 0.158
genitalia development GO:0048806 741 0.156
single organism localization GO:1902578 518 0.138
multicellular organismal aging GO:0010259 812 0.134
macromolecule localization GO:0033036 771 0.119
regulation of multicellular organismal process GO:0051239 726 0.119
muscle tissue development GO:0060537 1 0.116
neuron projection development GO:0031175 187 0.114
positive regulation of multicellular organismal process GO:0051240 417 0.112
single organism transport GO:0044765 447 0.109
cation transmembrane transport GO:0098655 59 0.106
regulation of biological quality GO:0065008 741 0.105
transmembrane transport GO:0055085 110 0.104
oviposition GO:0018991 364 0.102
single organism reproductive process GO:0044702 1196 0.101
aging GO:0007568 812 0.101
monovalent inorganic cation transport GO:0015672 33 0.101
cell cell signaling GO:0007267 118 0.101
regulation of multicellular organism growth GO:0040014 373 0.101
multi organism reproductive process GO:0044703 867 0.099
growth GO:0040007 562 0.093
inorganic cation transmembrane transport GO:0098662 46 0.092
organelle fission GO:0048285 363 0.091
metal ion transport GO:0030001 49 0.090
endocytosis GO:0006897 819 0.090
organ development GO:0048513 1102 0.088
regulation of growth GO:0040008 409 0.088
positive regulation of growth GO:0045927 369 0.087
negative regulation of biological process GO:0048519 567 0.087
cell development GO:0048468 696 0.086
regulation of developmental growth GO:0048638 389 0.082
ion transmembrane transport GO:0034220 91 0.079
gamete generation GO:0007276 461 0.079
organelle organization GO:0006996 783 0.077
head development GO:0060322 1 0.075
system process GO:0003008 136 0.075
multicellular organismal reproductive behavior GO:0033057 384 0.075
vesicle mediated transport GO:0016192 852 0.075
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.073
generation of neurons GO:0048699 235 0.073
maintenance of location GO:0051235 580 0.073
vulval development GO:0040025 333 0.071
cellular component morphogenesis GO:0032989 318 0.071
positive regulation of developmental growth GO:0048639 354 0.069
cellular component movement GO:0006928 388 0.069
developmental growth GO:0048589 412 0.068
lipid storage GO:0019915 565 0.068
synaptic transmission GO:0007268 106 0.067
development of primary sexual characteristics GO:0045137 840 0.067
negative regulation of nematode larval development GO:0061064 208 0.066
cellular macromolecular complex assembly GO:0034622 184 0.066
positive regulation of developmental process GO:0051094 408 0.066
positive regulation of multicellular organism growth GO:0040018 352 0.065
neuron development GO:0048666 199 0.065
regulation of synaptic transmission GO:0050804 34 0.064
meiotic nuclear division GO:0007126 300 0.064
secretion by cell GO:0032940 138 0.064
lipid localization GO:0010876 573 0.063
negative regulation of vulval development GO:0040027 206 0.061
cell death GO:0008219 547 0.061
cation transport GO:0006812 78 0.061
cell division GO:0051301 262 0.061
multi multicellular organism process GO:0044706 390 0.061
cell cycle process GO:0022402 482 0.061
programmed cell death GO:0012501 500 0.060
negative regulation of gene expression GO:0010629 217 0.059
localization of cell GO:0051674 313 0.059
signal transduction GO:0007165 317 0.058
receptor mediated endocytosis GO:0006898 715 0.058
death GO:0016265 547 0.058
protein catabolic process GO:0030163 162 0.058
single organism organelle organization GO:1902589 501 0.058
regulation of cell division GO:0051302 142 0.058
post embryonic organ development GO:0048569 336 0.057
single organism signaling GO:0044700 401 0.055
gonad development GO:0008406 840 0.054
behavior GO:0007610 527 0.054
protein metabolic process GO:0019538 422 0.053
determination of adult lifespan GO:0008340 812 0.052
multi organism reproductive behavior GO:0044705 387 0.052
macromolecule modification GO:0043412 218 0.051
multi organism behavior GO:0051705 389 0.051
taxis GO:0042330 128 0.051
macromolecular complex subunit organization GO:0043933 320 0.051
regulation of gene expression GO:0010468 366 0.050
negative regulation of metabolic process GO:0009892 240 0.049
negative regulation of developmental process GO:0051093 227 0.049
axon development GO:0061564 163 0.049
regulation of macromolecule metabolic process GO:0060255 421 0.048
muscle structure development GO:0061061 191 0.048
cellular component biogenesis GO:0044085 297 0.048
cellular component assembly GO:0022607 293 0.047
sensory organ morphogenesis GO:0090596 2 0.047
macromolecular complex assembly GO:0065003 193 0.047
inorganic ion transmembrane transport GO:0098660 54 0.047
cell motility GO:0048870 313 0.046
sex differentiation GO:0007548 909 0.046
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.046
protein complex assembly GO:0006461 186 0.046
neuron projection guidance GO:0097485 82 0.046
anatomical structure formation involved in morphogenesis GO:0048646 250 0.045
organelle assembly GO:0070925 214 0.045
response to chemical GO:0042221 356 0.045
reproductive structure development GO:0048608 850 0.045
cellular protein metabolic process GO:0044267 279 0.044
muscle cell development GO:0055001 158 0.043
meiotic cell cycle GO:0051321 335 0.043
regulation of nematode larval development GO:0061062 260 0.043
cell projection organization GO:0030030 231 0.043
immune response GO:0006955 192 0.042
anion transport GO:0006820 30 0.041
gene silencing by rna GO:0031047 143 0.041
cognition GO:0050890 27 0.041
axon guidance GO:0007411 82 0.039
striated muscle cell differentiation GO:0051146 158 0.039
rna interference GO:0016246 137 0.039
regulation of development heterochronic GO:0040034 18 0.039
memory GO:0007613 3 0.038
body morphogenesis GO:0010171 620 0.038
anion transmembrane transport GO:0098656 21 0.038
macromolecule catabolic process GO:0009057 202 0.037
cell cycle GO:0007049 526 0.037
reproductive behavior GO:0019098 387 0.037
gene silencing GO:0016458 143 0.036
protein complex subunit organization GO:0071822 280 0.036
female gamete generation GO:0007292 254 0.036
gene expression GO:0010467 412 0.036
cell morphogenesis GO:0000902 163 0.036
cellular component assembly involved in morphogenesis GO:0010927 183 0.036
secretion GO:0046903 147 0.035
positive regulation of neurogenesis GO:0050769 4 0.035
cell part morphogenesis GO:0032990 152 0.035
cell migration GO:0016477 306 0.035
regulation of vulval development GO:0040028 248 0.035
organic substance catabolic process GO:1901575 294 0.034
posttranscriptional regulation of gene expression GO:0010608 166 0.034
regulation of response to stimulus GO:0048583 243 0.033
negative regulation of multicellular organismal process GO:0051241 236 0.033
neurogenesis GO:0022008 236 0.033
hermaphrodite genitalia development GO:0040035 734 0.033
sexual reproduction GO:0019953 546 0.032
canonical wnt signaling pathway GO:0060070 3 0.032
negative regulation of macromolecule metabolic process GO:0010605 229 0.031
posttranscriptional gene silencing by rna GO:0035194 143 0.031
regulation of metabolic process GO:0019222 478 0.031
cellular protein modification process GO:0006464 207 0.031
catabolic process GO:0009056 318 0.031
posttranscriptional gene silencing GO:0016441 143 0.030
positive regulation of cellular process GO:0048522 332 0.030
regulation of cellular component organization GO:0051128 248 0.030
regulation of cell cycle GO:0051726 194 0.029
response to abiotic stimulus GO:0009628 152 0.029
neuron differentiation GO:0030182 217 0.029
defense response GO:0006952 296 0.029
eating behavior GO:0042755 59 0.028
signal release GO:0023061 28 0.028
muscle cell differentiation GO:0042692 171 0.028
protein phosphorylation GO:0006468 85 0.028
ribosome biogenesis GO:0042254 4 0.028
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.026
striated muscle myosin thick filament assembly GO:0071688 138 0.026
regulation of cell communication GO:0010646 176 0.026
protein modification process GO:0036211 207 0.026
negative regulation of post embryonic development GO:0048581 208 0.026
skeletal muscle organ development GO:0060538 3 0.026
negative regulation of cellular process GO:0048523 239 0.025
meiotic chromosome segregation GO:0045132 139 0.025
cytoskeleton organization GO:0007010 339 0.025
regulation of signal transduction GO:0009966 135 0.025
actomyosin structure organization GO:0031032 154 0.025
striated muscle cell development GO:0055002 157 0.025
oogenesis GO:0048477 229 0.024
neuron projection morphogenesis GO:0048812 114 0.024
epithelial tube morphogenesis GO:0060562 1 0.024
cell morphogenesis involved in differentiation GO:0000904 112 0.024
regulation of gene expression epigenetic GO:0040029 163 0.023
regulation of organ morphogenesis GO:2000027 4 0.023
myofibril assembly GO:0030239 154 0.023
regulation of post embryonic development GO:0048580 260 0.023
nervous system development GO:0007399 253 0.023
protein complex biogenesis GO:0070271 186 0.023
macromolecule biosynthetic process GO:0009059 250 0.022
reproductive system development GO:0061458 850 0.022
molting cycle GO:0042303 281 0.022
innate immune response GO:0045087 190 0.021
feeding behavior GO:0007631 70 0.020
regulation of meiotic cell cycle GO:0051445 136 0.020
negative regulation of neurogenesis GO:0050768 4 0.020
actin cytoskeleton organization GO:0030036 184 0.020
apoptotic process GO:0006915 478 0.020
cellular protein complex assembly GO:0043623 178 0.019
digestive system development GO:0055123 122 0.019
embryonic morphogenesis GO:0048598 152 0.019
regulation of cell cycle process GO:0010564 145 0.019
neuromuscular junction development GO:0007528 2 0.019
positive regulation of cell projection organization GO:0031346 4 0.018
negative regulation of cellular biosynthetic process GO:0031327 65 0.018
bmp signaling pathway GO:0030509 3 0.018
phagocytosis engulfment GO:0006911 98 0.018
cell projection morphogenesis GO:0048858 148 0.018
regulation of epithelial cell proliferation GO:0050678 1 0.018
phosphorus metabolic process GO:0006793 232 0.018
myosin filament organization GO:0031033 138 0.018
regulation of canonical wnt signaling pathway GO:0060828 1 0.018
positive regulation of neuron differentiation GO:0045666 4 0.017
germ cell development GO:0007281 351 0.017
response to external stimulus GO:0009605 289 0.017
cellular catabolic process GO:0044248 199 0.017
positive regulation of cell communication GO:0010647 69 0.017
establishment of localization in cell GO:0051649 318 0.017
regulation of cytoplasmic transport GO:1903649 3 0.017
protein localization GO:0008104 205 0.017
regulation of cellular localization GO:0060341 42 0.016
spindle organization GO:0007051 92 0.016
divalent inorganic cation transport GO:0072511 17 0.016
myosin filament assembly GO:0031034 138 0.016
phosphorylation GO:0016310 116 0.016
actin filament based process GO:0030029 191 0.016
axonogenesis GO:0007409 102 0.016
neuron neuron synaptic transmission GO:0007270 22 0.016
germ cell migration GO:0008354 1 0.016
regulation of mitotic cell cycle GO:0007346 76 0.016
regulation of nuclear division GO:0051783 115 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
cell recognition GO:0008037 85 0.015
intracellular transport GO:0046907 77 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.015
rhythmic behavior GO:0007622 3 0.015
positive regulation of stem cell differentiation GO:2000738 1 0.015
cellular macromolecule biosynthetic process GO:0034645 247 0.015
regulation of lipid transport GO:0032368 4 0.015
muscle contraction GO:0006936 43 0.015
single organism behavior GO:0044708 83 0.015
calcium ion transport GO:0006816 16 0.015
regulation of meiosis GO:0040020 94 0.015
response to biotic stimulus GO:0009607 101 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.014
cellular localization GO:0051641 360 0.014
organic substance transport GO:0071702 113 0.014
organic cyclic compound biosynthetic process GO:1901362 195 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.014
pigmentation GO:0043473 2 0.014
neuron recognition GO:0008038 83 0.014
regulation of phosphorylation GO:0042325 45 0.014
organonitrogen compound metabolic process GO:1901564 151 0.014
membrane invagination GO:0010324 98 0.014
axonal fasciculation GO:0007413 79 0.013
cell substrate adhesion GO:0031589 1 0.013
cell surface receptor signaling pathway GO:0007166 149 0.013
regulation of cellular metabolic process GO:0031323 305 0.013
neurotransmitter transport GO:0006836 32 0.013
transcription dna templated GO:0006351 168 0.013
cell type specific apoptotic process GO:0097285 4 0.013
regeneration GO:0031099 4 0.013
phagocytosis GO:0006909 115 0.013
cuticle development GO:0042335 100 0.013
transcription from rna polymerase ii promoter GO:0006366 149 0.012
intracellular signal transduction GO:0035556 96 0.012
intracellular receptor signaling pathway GO:0030522 2 0.012
dendrite development GO:0016358 42 0.012
regulation of localization GO:0032879 194 0.012
cytosolic calcium ion homeostasis GO:0051480 2 0.012
defense response to other organism GO:0098542 100 0.012
regulation of neurotransmitter levels GO:0001505 36 0.012
engulfment of apoptotic cell GO:0043652 94 0.012
proteolysis GO:0006508 61 0.012
neural precursor cell proliferation GO:0061351 9 0.012
chemotaxis GO:0006935 120 0.012
nucleic acid metabolic process GO:0090304 299 0.012
positive regulation of neuron projection development GO:0010976 4 0.012
inductive cell migration GO:0040039 145 0.012
ras protein signal transduction GO:0007265 31 0.011
neurotransmitter secretion GO:0007269 26 0.011
regulation of stem cell differentiation GO:2000736 1 0.011
learning or memory GO:0007611 27 0.011
positive regulation of cellular metabolic process GO:0031325 178 0.011
homeostatic process GO:0042592 51 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.011
regulation of lipid metabolic process GO:0019216 4 0.011
regulation of ion transport GO:0043269 39 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.011
developmental induction GO:0031128 1 0.011
regulation of lipid biosynthetic process GO:0046890 1 0.011
chromosome segregation GO:0007059 180 0.011
peptidyl tyrosine phosphorylation GO:0018108 2 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
cellular biosynthetic process GO:0044249 315 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
mitotic nuclear division GO:0007067 89 0.011
regulation of calcium ion transport GO:0051924 3 0.011
tissue development GO:0009888 112 0.011
regulation of synapse assembly GO:0051963 2 0.011
amine metabolic process GO:0009308 15 0.011
positive regulation of metabolic process GO:0009893 187 0.011
male sex differentiation GO:0046661 86 0.011
neurological system process GO:0050877 53 0.010
protein oligomerization GO:0051259 4 0.010
trna metabolic process GO:0006399 3 0.010
regulation of cell death GO:0010941 65 0.010
regulation of response to wounding GO:1903034 1 0.010
dna metabolic process GO:0006259 74 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
cellular response to abiotic stimulus GO:0071214 4 0.010
cell proliferation GO:0008283 116 0.010
nematode male tail tip morphogenesis GO:0045138 77 0.010

unc-49 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.012