Caenorhabditis elegans

85 known processes

sin-3 (CELE_F02E9.4)

Protein SIN-3

sin-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.862
embryo development ending in birth or egg hatching GO:0009792 2992 0.754
post embryonic development GO:0009791 2152 0.659
gonad development GO:0008406 840 0.536
developmental process involved in reproduction GO:0003006 1165 0.445
establishment of localization GO:0051234 1171 0.439
multicellular organism reproduction GO:0032504 819 0.437
single organism reproductive process GO:0044702 1196 0.418
single organism localization GO:1902578 518 0.385
multi organism reproductive process GO:0044703 867 0.375
transport GO:0006810 1093 0.359
regulation of cellular metabolic process GO:0031323 305 0.340
Human Mouse Fly
regulation of gene expression GO:0010468 366 0.338
organ development GO:0048513 1102 0.338
sex differentiation GO:0007548 909 0.320
cell cycle process GO:0022402 482 0.284
Mouse
genitalia development GO:0048806 741 0.273
transcription dna templated GO:0006351 168 0.264
Human Mouse Fly
establishment of localization in cell GO:0051649 318 0.263
positive regulation of rna biosynthetic process GO:1902680 102 0.260
Human
programmed cell death GO:0012501 500 0.253
Mouse
gamete generation GO:0007276 461 0.248
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.248
Human
death GO:0016265 547 0.245
Mouse
apoptotic process GO:0006915 478 0.243
Mouse
reproductive structure development GO:0048608 850 0.239
meiotic chromosome segregation GO:0045132 139 0.234
germ cell development GO:0007281 351 0.229
transcription from rna polymerase ii promoter GO:0006366 149 0.226
Human Mouse
reproductive system development GO:0061458 850 0.220
body morphogenesis GO:0010171 620 0.216
hermaphrodite genitalia development GO:0040035 734 0.212
post embryonic organ development GO:0048569 336 0.204
locomotion GO:0040011 1634 0.201
determination of adult lifespan GO:0008340 812 0.188
Fly
development of primary sexual characteristics GO:0045137 840 0.187
gene expression GO:0010467 412 0.186
vesicle mediated transport GO:0016192 852 0.180
rna metabolic process GO:0016070 228 0.176
Human Mouse Fly
positive regulation of cellular process GO:0048522 332 0.175
Human Mouse
regulation of multicellular organismal process GO:0051239 726 0.168
nucleobase containing compound metabolic process GO:0006139 406 0.163
Human Mouse Fly
positive regulation of gene expression GO:0010628 112 0.159
Human
female gamete generation GO:0007292 254 0.154
positive regulation of multicellular organismal process GO:0051240 417 0.153
protein metabolic process GO:0019538 422 0.148
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.140
regulation of developmental process GO:0050793 684 0.138
sexual reproduction GO:0019953 546 0.135
regulation of transcription dna templated GO:0006355 164 0.131
Human Mouse Fly
multicellular organismal reproductive process GO:0048609 815 0.126
aging GO:0007568 812 0.126
Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.125
Human Mouse Fly
meiotic nuclear division GO:0007126 300 0.122
catabolic process GO:0009056 318 0.120
multicellular organism growth GO:0035264 385 0.114
regulation of rna metabolic process GO:0051252 173 0.113
Human Mouse Fly
cell death GO:0008219 547 0.111
Mouse
receptor mediated endocytosis GO:0006898 715 0.109
cellular localization GO:0051641 360 0.109
Human Mouse
organelle organization GO:0006996 783 0.109
endocytosis GO:0006897 819 0.106
cell motility GO:0048870 313 0.105
Fly
macromolecule modification GO:0043412 218 0.103
rna biosynthetic process GO:0032774 169 0.099
Human Mouse Fly
single organism organelle organization GO:1902589 501 0.098
biosynthetic process GO:0009058 323 0.098
Human Mouse Fly
single organism transport GO:0044765 447 0.096
cellular biosynthetic process GO:0044249 315 0.093
Human Mouse Fly
multicellular organismal aging GO:0010259 812 0.091
Fly
regulation of nucleic acid templated transcription GO:1903506 165 0.088
Human Mouse Fly
cell cycle GO:0007049 526 0.087
Mouse Fly
regulation of cellular biosynthetic process GO:0031326 189 0.087
Human Mouse Fly
posttranscriptional gene silencing GO:0016441 143 0.084
regulation of metabolic process GO:0019222 478 0.082
negative regulation of macromolecule metabolic process GO:0010605 229 0.079
neuron projection development GO:0031175 187 0.078
Fly
response to abiotic stimulus GO:0009628 152 0.077
multi multicellular organism process GO:0044706 390 0.077
regulation of biological quality GO:0065008 741 0.077
Mouse Fly
regulation of gene expression epigenetic GO:0040029 163 0.077
organic substance biosynthetic process GO:1901576 323 0.076
Human Mouse Fly
regulation of post embryonic development GO:0048580 260 0.076
macromolecule biosynthetic process GO:0009059 250 0.071
Human Mouse Fly
cell projection organization GO:0030030 231 0.069
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.069
Human Mouse Fly
growth GO:0040007 562 0.068
vulval development GO:0040025 333 0.068
rna interference GO:0016246 137 0.067
positive regulation of transcription dna templated GO:0045893 102 0.066
Human
gene silencing GO:0016458 143 0.064
nucleic acid metabolic process GO:0090304 299 0.063
Human Mouse Fly
cell division GO:0051301 262 0.061
negative regulation of cellular process GO:0048523 239 0.061
Human Mouse Fly
regulation of cell cycle process GO:0010564 145 0.060
Mouse
positive regulation of developmental growth GO:0048639 354 0.059
macromolecule catabolic process GO:0009057 202 0.058
multicellular organismal reproductive behavior GO:0033057 384 0.057
positive regulation of developmental process GO:0051094 408 0.057
chromosome organization involved in meiosis GO:0070192 25 0.057
meiotic cell cycle process GO:1903046 170 0.057
maintenance of location GO:0051235 580 0.057
head development GO:0060322 1 0.056
response to bacterium GO:0009617 86 0.056
protein phosphorylation GO:0006468 85 0.056
macromolecule localization GO:0033036 771 0.055
Human Mouse
lipid localization GO:0010876 573 0.055
actin filament based process GO:0030029 191 0.055
chromosome segregation GO:0007059 180 0.055
lipid storage GO:0019915 565 0.054
positive regulation of metabolic process GO:0009893 187 0.054
Human
regulation of multicellular organismal development GO:2000026 317 0.053
reproductive behavior GO:0019098 387 0.052
positive regulation of rna metabolic process GO:0051254 103 0.051
Human
regulation of cell cycle GO:0051726 194 0.050
Mouse Fly
posttranscriptional gene silencing by rna GO:0035194 143 0.048
negative regulation of metabolic process GO:0009892 240 0.047
regulation of primary metabolic process GO:0080090 292 0.047
Human Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.047
Human Mouse Fly
positive regulation of macromolecule metabolic process GO:0010604 149 0.047
Human
mitotic cell cycle process GO:1903047 194 0.046
Mouse
single organism signaling GO:0044700 401 0.045
Fly
regulation of developmental growth GO:0048638 389 0.045
cell migration GO:0016477 306 0.045
Fly
gene silencing by rna GO:0031047 143 0.044
positive regulation of growth GO:0045927 369 0.044
multi organism behavior GO:0051705 389 0.043
regulation of biosynthetic process GO:0009889 189 0.043
Human Mouse Fly
protein modification process GO:0036211 207 0.043
cellular component assembly involved in morphogenesis GO:0010927 183 0.042
oviposition GO:0018991 364 0.042
regulation of macromolecule metabolic process GO:0060255 421 0.041
cell type specific apoptotic process GO:0097285 4 0.041
phosphate containing compound metabolic process GO:0006796 232 0.041
regulation of multicellular organism growth GO:0040014 373 0.041
small molecule metabolic process GO:0044281 186 0.041
positive regulation of multicellular organism growth GO:0040018 352 0.040
regulation of macromolecule biosynthetic process GO:0010556 189 0.040
Human Mouse Fly
negative regulation of nematode larval development GO:0061064 208 0.038
neuron differentiation GO:0030182 217 0.038
Fly
heterocycle biosynthetic process GO:0018130 187 0.037
Human Mouse Fly
organic substance catabolic process GO:1901575 294 0.037
phagocytosis GO:0006909 115 0.036
positive regulation of cellular metabolic process GO:0031325 178 0.035
Human
cellular component morphogenesis GO:0032989 318 0.035
Fly
nucleic acid templated transcription GO:0097659 169 0.034
Human Mouse Fly
behavior GO:0007610 527 0.034
negative regulation of biological process GO:0048519 567 0.033
cellular protein modification process GO:0006464 207 0.032
sister chromatid segregation GO:0000819 46 0.032
negative regulation of gene expression GO:0010629 217 0.032
cellular catabolic process GO:0044248 199 0.031
response to external stimulus GO:0009605 289 0.031
Human
membrane organization GO:0061024 135 0.030
signal transduction GO:0007165 317 0.030
Fly
defense response GO:0006952 296 0.030
Human
chromatin modification GO:0016568 32 0.030
cellular macromolecule biosynthetic process GO:0034645 247 0.030
Human Mouse Fly
regulation of mitotic cell cycle GO:0007346 76 0.029
Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.029
Human
response to other organism GO:0051707 101 0.029
Human
regulation of organelle organization GO:0033043 164 0.029
Human
oogenesis GO:0048477 229 0.028
positive regulation of cellular biosynthetic process GO:0031328 109 0.028
Human
meiotic cell cycle GO:0051321 335 0.028
negative regulation of cellular metabolic process GO:0031324 95 0.028
Human Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.028
Human Mouse Fly
regulation of growth GO:0040008 409 0.027
organelle fission GO:0048285 363 0.027
negative regulation of developmental process GO:0051093 227 0.027
cellular protein metabolic process GO:0044267 279 0.027
negative regulation of vulval development GO:0040027 206 0.026
actin cytoskeleton organization GO:0030036 184 0.025
negative regulation of biosynthetic process GO:0009890 65 0.025
Human Mouse Fly
cellular component biogenesis GO:0044085 297 0.025
regulation of vulval development GO:0040028 248 0.025
multi organism reproductive behavior GO:0044705 387 0.025
cell development GO:0048468 696 0.025
Fly
regulation of cell motility GO:2000145 57 0.025
Fly
intracellular signal transduction GO:0035556 96 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.024
Human Mouse Fly
chromosome organization GO:0051276 104 0.024
neurological system process GO:0050877 53 0.024
inductive cell migration GO:0040039 145 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.023
Human
organic substance transport GO:0071702 113 0.023
developmental growth GO:0048589 412 0.023
chemotaxis GO:0006935 120 0.023
muscle cell development GO:0055001 158 0.022
myofibril assembly GO:0030239 154 0.022
phosphorus metabolic process GO:0006793 232 0.022
striated muscle cell development GO:0055002 157 0.021
negative regulation of nucleic acid templated transcription GO:1903507 53 0.020
Human Mouse Fly
regulation of rna biosynthetic process GO:2001141 165 0.020
Human Mouse Fly
negative regulation of multicellular organismal process GO:0051241 236 0.020
defense response to bacterium GO:0042742 86 0.020
response to chemical GO:0042221 356 0.020
Mouse
cell projection morphogenesis GO:0048858 148 0.020
Fly
epithelial cell morphogenesis GO:0003382 2 0.020
apoptotic cell clearance GO:0043277 111 0.020
engulfment of apoptotic cell GO:0043652 94 0.019
localization of cell GO:0051674 313 0.019
Fly
cell part morphogenesis GO:0032990 152 0.019
Fly
defense response to other organism GO:0098542 100 0.019
Human
histone modification GO:0016570 30 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
positive regulation of biosynthetic process GO:0009891 109 0.018
Human
rna localization GO:0006403 3 0.018
axon development GO:0061564 163 0.018
posttranscriptional regulation of gene expression GO:0010608 166 0.018
regulation of nematode larval development GO:0061062 260 0.018
intracellular transport GO:0046907 77 0.017
cellular component movement GO:0006928 388 0.017
Fly
striated muscle cell differentiation GO:0051146 158 0.017
chromatin remodeling GO:0006338 2 0.017
nucleoside triphosphate metabolic process GO:0009141 87 0.017
cellular response to organic substance GO:0071310 119 0.016
Mouse
positive regulation of cell cycle GO:0045787 55 0.016
Mouse
muscle cell differentiation GO:0042692 171 0.016
rna transport GO:0050658 3 0.016
organelle assembly GO:0070925 214 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.016
Human Mouse Fly
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.016
macromolecular complex assembly GO:0065003 193 0.016
internal peptidyl lysine acetylation GO:0018393 3 0.016
Human
single organism carbohydrate metabolic process GO:0044723 29 0.016
cellular macromolecule catabolic process GO:0044265 73 0.016
ribonucleotide metabolic process GO:0009259 99 0.015
system process GO:0003008 136 0.015
cuticle development GO:0042335 100 0.015
cytoskeleton organization GO:0007010 339 0.015
cellular response to nitrogen compound GO:1901699 24 0.015
cellular response to abiotic stimulus GO:0071214 4 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.015
regulation of localization GO:0032879 194 0.015
Human Fly
cell morphogenesis GO:0000902 163 0.014
Fly
response to organic substance GO:0010033 131 0.014
Mouse
phagocytosis engulfment GO:0006911 98 0.014
regulation of cell division GO:0051302 142 0.014
lipid metabolic process GO:0006629 77 0.014
regulation of organ morphogenesis GO:2000027 4 0.014
mitotic sister chromatid segregation GO:0000070 38 0.014
regulation of reproductive process GO:2000241 66 0.014
collagen and cuticulin based cuticle development GO:0040002 99 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
muscle structure development GO:0061061 191 0.014
Mouse Fly
actomyosin structure organization GO:0031032 154 0.013
positive regulation of protein transport GO:0051222 4 0.013
signaling GO:0023052 401 0.013
Fly
regulation of cellular component organization GO:0051128 248 0.013
Human
regulation of apoptotic signaling pathway GO:2001233 1 0.013
taxis GO:0042330 128 0.013
regulation of intracellular signal transduction GO:1902531 77 0.013
cellular response to topologically incorrect protein GO:0035967 76 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
anatomical structure formation involved in morphogenesis GO:0048646 250 0.013
protein catabolic process GO:0030163 162 0.013
response to biotic stimulus GO:0009607 101 0.013
Human
positive regulation of nucleic acid templated transcription GO:1903508 102 0.013
Human
nervous system development GO:0007399 253 0.012
Fly
molting cycle GO:0042303 281 0.012
negative regulation of response to stimulus GO:0048585 73 0.012
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
Human Mouse Fly
response to nitrogen compound GO:1901698 25 0.012
regulation of cell proliferation GO:0042127 105 0.012
Fly
cellular response to chemical stimulus GO:0070887 129 0.012
Mouse
innate immune response GO:0045087 190 0.012
Human
cellular nitrogen compound catabolic process GO:0044270 119 0.012
amine metabolic process GO:0009308 15 0.012
covalent chromatin modification GO:0016569 30 0.012
response to topologically incorrect protein GO:0035966 82 0.011
myosin filament assembly GO:0031034 138 0.011
neuromuscular junction development GO:0007528 2 0.011
cellular amine metabolic process GO:0044106 15 0.011
organophosphate catabolic process GO:0046434 81 0.011
cellular response to stress GO:0033554 162 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
positive regulation of neurogenesis GO:0050769 4 0.011
regulation of cytoplasmic transport GO:1903649 3 0.011
epithelial tube morphogenesis GO:0060562 1 0.011
response to temperature stimulus GO:0009266 66 0.011
positive regulation of intracellular transport GO:0032388 2 0.011
peptidyl amino acid modification GO:0018193 58 0.011
Human
peptidyl lysine acetylation GO:0018394 3 0.011
Human
positive regulation of protein metabolic process GO:0051247 45 0.011
membrane invagination GO:0010324 98 0.011
ras protein signal transduction GO:0007265 31 0.011
purine nucleotide catabolic process GO:0006195 75 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.011
Human
generation of neurons GO:0048699 235 0.011
Fly
secretion by cell GO:0032940 138 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
negative regulation of rna metabolic process GO:0051253 53 0.010
Human Mouse Fly
response to external biotic stimulus GO:0043207 101 0.010
Human
negative regulation of cell cycle GO:0045786 53 0.010
protein homooligomerization GO:0051260 3 0.010
nucleobase containing compound biosynthetic process GO:0034654 184 0.010
Human Mouse Fly
regulation of cellular amine metabolic process GO:0033238 0 0.010
single organism intracellular transport GO:1902582 70 0.010
organic acid metabolic process GO:0006082 47 0.010

sin-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.106
cancer DOID:162 0 0.106
disease of cellular proliferation DOID:14566 0 0.106
organ system cancer DOID:0050686 0 0.106
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.011