Caenorhabditis elegans

31 known processes

nrd-1 (CELE_D1007.7)

Protein NRD-1

nrd-1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of vulval development GO:0040028 248 0.596
vulval development GO:0040025 333 0.457
embryo development ending in birth or egg hatching GO:0009792 2992 0.364
post embryonic organ development GO:0048569 336 0.305
cell cycle process GO:0022402 482 0.284
embryo development GO:0009790 3052 0.253
organ development GO:0048513 1102 0.249
cell cycle GO:0007049 526 0.240
locomotion GO:0040011 1634 0.225
rna metabolic process GO:0016070 228 0.219
Rat
cellular component movement GO:0006928 388 0.210
organelle fission GO:0048285 363 0.205
developmental process involved in reproduction GO:0003006 1165 0.181
heterocycle biosynthetic process GO:0018130 187 0.175
Rat
negative regulation of vulval development GO:0040027 206 0.173
cell development GO:0048468 696 0.163
regulation of nematode larval development GO:0061062 260 0.151
regulation of nucleic acid templated transcription GO:1903506 165 0.145
meiotic nuclear division GO:0007126 300 0.144
negative regulation of nematode larval development GO:0061064 208 0.141
negative regulation of post embryonic development GO:0048581 208 0.137
organelle organization GO:0006996 783 0.133
cellular protein modification process GO:0006464 207 0.126
regulation of macromolecule metabolic process GO:0060255 421 0.123
post embryonic development GO:0009791 2152 0.123
generation of neurons GO:0048699 235 0.120
negative regulation of multicellular organismal process GO:0051241 236 0.118
regulation of rna biosynthetic process GO:2001141 165 0.114
transport GO:0006810 1093 0.112
multicellular organismal reproductive behavior GO:0033057 384 0.110
organic cyclic compound biosynthetic process GO:1901362 195 0.109
Rat
behavior GO:0007610 527 0.107
mitotic cell cycle process GO:1903047 194 0.103
chromosome organization GO:0051276 104 0.100
nucleic acid metabolic process GO:0090304 299 0.097
Rat
positive regulation of biosynthetic process GO:0009891 109 0.096
nucleobase containing compound biosynthetic process GO:0034654 184 0.095
Rat
meiotic cell cycle GO:0051321 335 0.095
cell motility GO:0048870 313 0.094
single organism organelle organization GO:1902589 501 0.093
gonad development GO:0008406 840 0.092
establishment of localization GO:0051234 1171 0.092
cell migration GO:0016477 306 0.092
reproductive behavior GO:0019098 387 0.091
regulation of developmental process GO:0050793 684 0.091
oviposition GO:0018991 364 0.088
sexual reproduction GO:0019953 546 0.083
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.083
macromolecule modification GO:0043412 218 0.081
multi organism reproductive process GO:0044703 867 0.081
gamete generation GO:0007276 461 0.075
regulation of biological quality GO:0065008 741 0.074
multi organism reproductive behavior GO:0044705 387 0.073
multi organism behavior GO:0051705 389 0.073
regulation of cellular biosynthetic process GO:0031326 189 0.072
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.071
endocytosis GO:0006897 819 0.069
macromolecule localization GO:0033036 771 0.069
localization of cell GO:0051674 313 0.069
single organism signaling GO:0044700 401 0.069
regulation of organelle organization GO:0033043 164 0.069
regulation of biosynthetic process GO:0009889 189 0.067
positive regulation of metabolic process GO:0009893 187 0.067
positive regulation of nematode larval development GO:0061063 54 0.066
cellular component morphogenesis GO:0032989 318 0.066
macromolecule biosynthetic process GO:0009059 250 0.065
Rat
phosphorus metabolic process GO:0006793 232 0.065
aromatic compound biosynthetic process GO:0019438 192 0.065
Rat
regulation of cell cycle GO:0051726 194 0.064
protein modification process GO:0036211 207 0.063
multicellular organismal reproductive process GO:0048609 815 0.062
programmed cell death GO:0012501 500 0.062
regulation of metabolic process GO:0019222 478 0.062
regulation of transcription dna templated GO:0006355 164 0.061
multi multicellular organism process GO:0044706 390 0.061
negative regulation of biological process GO:0048519 567 0.061
maintenance of location GO:0051235 580 0.060
microtubule based process GO:0007017 182 0.059
single organism reproductive process GO:0044702 1196 0.059
positive regulation of gene expression GO:0010628 112 0.057
nucleic acid templated transcription GO:0097659 169 0.056
Rat
regulation of chromosome organization GO:0033044 20 0.056
lipid localization GO:0010876 573 0.055
lipid storage GO:0019915 565 0.055
aging GO:0007568 812 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.054
cellular protein metabolic process GO:0044267 279 0.053
positive regulation of vulval development GO:0040026 52 0.053
determination of adult lifespan GO:0008340 812 0.053
tube development GO:0035295 126 0.051
regulation of cellular metabolic process GO:0031323 305 0.051
regulation of gene expression epigenetic GO:0040029 163 0.051
neuron development GO:0048666 199 0.051
neurogenesis GO:0022008 236 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.050
multicellular organismal aging GO:0010259 812 0.050
negative regulation of developmental process GO:0051093 227 0.049
germ cell development GO:0007281 351 0.049
signaling GO:0023052 401 0.048
regulation of rna metabolic process GO:0051252 173 0.048
regulation of multicellular organismal process GO:0051239 726 0.048
signal transduction GO:0007165 317 0.047
digestive system development GO:0055123 122 0.047
biosynthetic process GO:0009058 323 0.046
Rat
regulation of locomotion GO:0040012 161 0.046
regulation of cell cycle process GO:0010564 145 0.046
positive regulation of cellular metabolic process GO:0031325 178 0.045
regulation of response to wounding GO:1903034 1 0.045
tissue development GO:0009888 112 0.045
regulation of macromolecule biosynthetic process GO:0010556 189 0.044
cellular component assembly GO:0022607 293 0.044
regulation of gene expression GO:0010468 366 0.043
cellular localization GO:0051641 360 0.042
development of primary sexual characteristics GO:0045137 840 0.042
regulation of meiosis GO:0040020 94 0.041
cell morphogenesis GO:0000902 163 0.041
positive regulation of post embryonic development GO:0048582 54 0.041
rna biosynthetic process GO:0032774 169 0.041
Rat
multicellular organism reproduction GO:0032504 819 0.040
regulation of ras protein signal transduction GO:0046578 41 0.040
molting cycle GO:0042303 281 0.039
cell death GO:0008219 547 0.039
regulation of nuclear division GO:0051783 115 0.039
histone modification GO:0016570 30 0.039
ras protein signal transduction GO:0007265 31 0.039
cytoskeleton organization GO:0007010 339 0.038
receptor mediated endocytosis GO:0006898 715 0.038
regulation of cellular component organization GO:0051128 248 0.038
intracellular receptor signaling pathway GO:0030522 2 0.038
cellular component biogenesis GO:0044085 297 0.038
reproductive structure development GO:0048608 850 0.038
organic substance biosynthetic process GO:1901576 323 0.038
Rat
body morphogenesis GO:0010171 620 0.037
small gtpase mediated signal transduction GO:0007264 32 0.037
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.037
regulation of meiotic cell cycle GO:0051445 136 0.037
vesicle mediated transport GO:0016192 852 0.037
regulation of cytoplasmic transport GO:1903649 3 0.037
positive regulation of cellular process GO:0048522 332 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.036
cell division GO:0051301 262 0.035
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.035
reproductive system development GO:0061458 850 0.035
positive regulation of macromolecule metabolic process GO:0010604 149 0.034
negative regulation of transcription dna templated GO:0045892 53 0.034
regulation of cell migration GO:0030334 55 0.034
cellular nitrogen compound biosynthetic process GO:0044271 192 0.034
Rat
chromosome segregation GO:0007059 180 0.033
gene expression GO:0010467 412 0.033
Rat
single organism transport GO:0044765 447 0.033
regulation of nucleocytoplasmic transport GO:0046822 3 0.033
cell fate commitment GO:0045165 139 0.033
anatomical structure formation involved in morphogenesis GO:0048646 250 0.032
mitotic nuclear division GO:0007067 89 0.032
nucleobase containing compound metabolic process GO:0006139 406 0.032
Rat
transcription dna templated GO:0006351 168 0.032
Rat
cell recognition GO:0008037 85 0.031
death GO:0016265 547 0.031
cell projection organization GO:0030030 231 0.031
cellular nitrogen compound catabolic process GO:0044270 119 0.031
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.031
positive regulation of nucleic acid templated transcription GO:1903508 102 0.030
cellular biosynthetic process GO:0044249 315 0.030
Rat
negative regulation of cellular biosynthetic process GO:0031327 65 0.029
phosphate containing compound metabolic process GO:0006796 232 0.028
single organism localization GO:1902578 518 0.028
regulation of primary metabolic process GO:0080090 292 0.028
regulation of multicellular organismal development GO:2000026 317 0.027
organelle assembly GO:0070925 214 0.027
apoptotic process GO:0006915 478 0.027
neuron differentiation GO:0030182 217 0.026
regulation of post embryonic development GO:0048580 260 0.026
negative regulation of gene expression epigenetic GO:0045814 2 0.026
regulation of growth GO:0040008 409 0.026
neuron projection development GO:0031175 187 0.025
rho protein signal transduction GO:0007266 2 0.024
regulation of cell division GO:0051302 142 0.024
regulation of nitrogen compound metabolic process GO:0051171 222 0.024
regulation of response to stimulus GO:0048583 243 0.024
cell proliferation GO:0008283 116 0.024
neuron projection morphogenesis GO:0048812 114 0.024
chromatin modification GO:0016568 32 0.023
regulation of developmental growth GO:0048638 389 0.023
hermaphrodite genitalia development GO:0040035 734 0.023
male sex differentiation GO:0046661 86 0.023
response to chemical GO:0042221 356 0.023
cellular macromolecule biosynthetic process GO:0034645 247 0.022
Rat
protein metabolic process GO:0019538 422 0.022
cellular macromolecular complex assembly GO:0034622 184 0.022
cellular response to dna damage stimulus GO:0006974 41 0.021
taxis GO:0042330 128 0.021
small molecule metabolic process GO:0044281 186 0.021
growth GO:0040007 562 0.021
catabolic process GO:0009056 318 0.021
positive regulation of protein transport GO:0051222 4 0.020
epithelial cell proliferation GO:0050673 1 0.020
digestive tract development GO:0048565 122 0.020
regulation of cell communication GO:0010646 176 0.020
nervous system development GO:0007399 253 0.020
regulation of multicellular organism growth GO:0040014 373 0.020
sex differentiation GO:0007548 909 0.020
axon guidance GO:0007411 82 0.020
nucleobase containing compound catabolic process GO:0034655 114 0.020
inductive cell migration GO:0040039 145 0.020
dna templated transcription elongation GO:0006354 1 0.020
positive regulation of intracellular transport GO:0032388 2 0.020
genitalia development GO:0048806 741 0.019
positive regulation of multicellular organismal process GO:0051240 417 0.019
positive regulation of transcription dna templated GO:0045893 102 0.019
negative regulation of metabolic process GO:0009892 240 0.019
cell type specific apoptotic process GO:0097285 4 0.019
cell morphogenesis involved in differentiation GO:0000904 112 0.019
organophosphate metabolic process GO:0019637 125 0.019
ribonucleoprotein complex assembly GO:0022618 4 0.018
regulation of organ morphogenesis GO:2000027 4 0.018
macromolecular complex assembly GO:0065003 193 0.018
response to external stimulus GO:0009605 289 0.018
positive regulation of multicellular organism growth GO:0040018 352 0.018
response to abiotic stimulus GO:0009628 152 0.018
organelle localization GO:0051640 127 0.018
chemotaxis GO:0006935 120 0.018
secretion by cell GO:0032940 138 0.017
macromolecule catabolic process GO:0009057 202 0.017
positive regulation of cellular protein catabolic process GO:1903364 3 0.017
cell surface receptor signaling pathway GO:0007166 149 0.016
spindle localization GO:0051653 51 0.016
protein modification by small protein conjugation or removal GO:0070647 40 0.016
positive regulation of rna metabolic process GO:0051254 103 0.016
meiotic cell cycle process GO:1903046 170 0.016
internal peptidyl lysine acetylation GO:0018393 3 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.016
glycosyl compound catabolic process GO:1901658 79 0.016
positive regulation of nucleotide catabolic process GO:0030813 28 0.016
regulation of catalytic activity GO:0050790 78 0.016
covalent chromatin modification GO:0016569 30 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.015
macromolecular complex subunit organization GO:0043933 320 0.015
positive regulation of chromosome organization GO:2001252 2 0.015
positive regulation of chromosome segregation GO:0051984 1 0.015
regulation of small gtpase mediated signal transduction GO:0051056 41 0.015
organic substance transport GO:0071702 113 0.015
gastrulation GO:0007369 58 0.015
positive regulation of developmental growth GO:0048639 354 0.015
neuron recognition GO:0008038 83 0.015
single organism cellular localization GO:1902580 72 0.014
establishment of organelle localization GO:0051656 123 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.014
negative regulation of macromolecule metabolic process GO:0010605 229 0.014
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.014
protein complex biogenesis GO:0070271 186 0.014
regulation of molecular function GO:0065009 89 0.014
organic cyclic compound catabolic process GO:1901361 119 0.014
regulation of protein targeting GO:1903533 3 0.014
spindle organization GO:0007051 92 0.014
organic acid metabolic process GO:0006082 47 0.014
regulation of cytoplasmic mrna processing body assembly GO:0010603 1 0.014
ectoderm development GO:0007398 3 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.013
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.013
chromatin remodeling GO:0006338 2 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
positive regulation of cellular biosynthetic process GO:0031328 109 0.013
cell part morphogenesis GO:0032990 152 0.013
regulation of cell motility GO:2000145 57 0.013
negative regulation of cellular process GO:0048523 239 0.013
cellular response to stress GO:0033554 162 0.013
mitotic sister chromatid segregation GO:0000070 38 0.013
positive regulation of phosphorus metabolic process GO:0010562 56 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
positive regulation of developmental process GO:0051094 408 0.013
positive regulation of signaling GO:0023056 66 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.013
developmental growth GO:0048589 412 0.013
response to wounding GO:0009611 4 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
positive regulation of growth GO:0045927 369 0.012
regulation of chromatin modification GO:1903308 2 0.012
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.012
cellular amine metabolic process GO:0044106 15 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
negative regulation of rna biosynthetic process GO:1902679 53 0.012
nematode male tail tip morphogenesis GO:0045138 77 0.012
gene silencing GO:0016458 143 0.012
male anatomical structure morphogenesis GO:0090598 78 0.012
system process GO:0003008 136 0.012
meiotic chromosome segregation GO:0045132 139 0.012
regulation of protein metabolic process GO:0051246 81 0.012
regulation of signal transduction GO:0009966 135 0.012
phosphorylation GO:0016310 116 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.011
cuticle development GO:0042335 100 0.011
amine metabolic process GO:0009308 15 0.011
neuromuscular junction development GO:0007528 2 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
cellular protein localization GO:0034613 75 0.011
regulation of signaling GO:0023051 172 0.011
male gamete generation GO:0048232 41 0.011
head development GO:0060322 1 0.011
oxoacid metabolic process GO:0043436 47 0.011
sensory organ morphogenesis GO:0090596 2 0.011
organic substance catabolic process GO:1901575 294 0.011
cellular response to chemical stimulus GO:0070887 129 0.011
regulation of mitotic cell cycle GO:0007346 76 0.011
regulation of cell differentiation GO:0045595 81 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
regulation of cellular localization GO:0060341 42 0.010
feminization of hermaphroditic germ line GO:0040022 34 0.010
regulation of cellular component movement GO:0051270 62 0.010
regulation of cellular protein metabolic process GO:0032268 75 0.010
internal protein amino acid acetylation GO:0006475 3 0.010
regulation of chromatin organization GO:1902275 2 0.010
regulation of cell proliferation GO:0042127 105 0.010
positive regulation of ras gtpase activity GO:0032320 19 0.010
negative regulation of response to external stimulus GO:0032102 3 0.010
negative regulation of mitotic cell cycle GO:0045930 42 0.010

nrd-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.015