Caenorhabditis elegans

41 known processes

amx-2 (CELE_B0019.1)

Protein AMX-2

amx-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sex differentiation GO:0007548 909 0.536
developmental process involved in reproduction GO:0003006 1165 0.533
embryo development ending in birth or egg hatching GO:0009792 2992 0.523
locomotion GO:0040011 1634 0.476
embryo development GO:0009790 3052 0.451
post embryonic development GO:0009791 2152 0.432
organ development GO:0048513 1102 0.375
single organism reproductive process GO:0044702 1196 0.303
cellular response to chemical stimulus GO:0070887 129 0.296
regulation of developmental process GO:0050793 684 0.291
transport GO:0006810 1093 0.278
development of primary sexual characteristics GO:0045137 840 0.261
reproductive system development GO:0061458 850 0.260
hermaphrodite genitalia development GO:0040035 734 0.223
body morphogenesis GO:0010171 620 0.217
genitalia development GO:0048806 741 0.210
establishment of localization GO:0051234 1171 0.207
response to chemical GO:0042221 356 0.201
gonad development GO:0008406 840 0.185
regulation of multicellular organismal process GO:0051239 726 0.183
reproductive structure development GO:0048608 850 0.181
muscle organ morphogenesis GO:0048644 4 0.177
positive regulation of developmental process GO:0051094 408 0.168
molting cycle GO:0042303 281 0.167
single organism transport GO:0044765 447 0.151
vesicle mediated transport GO:0016192 852 0.147
growth GO:0040007 562 0.142
multicellular organismal aging GO:0010259 812 0.141
regulation of growth GO:0040008 409 0.140
determination of adult lifespan GO:0008340 812 0.139
nucleobase containing compound metabolic process GO:0006139 406 0.136
cellular biosynthetic process GO:0044249 315 0.128
signaling GO:0023052 401 0.127
regulation of developmental growth GO:0048638 389 0.126
aging GO:0007568 812 0.124
organic substance biosynthetic process GO:1901576 323 0.118
multicellular organism growth GO:0035264 385 0.118
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.118
endocytosis GO:0006897 819 0.117
positive regulation of developmental growth GO:0048639 354 0.114
nucleic acid templated transcription GO:0097659 169 0.112
muscle tissue development GO:0060537 1 0.109
regulation of response to stimulus GO:0048583 243 0.108
macromolecule localization GO:0033036 771 0.108
transcription from rna polymerase ii promoter GO:0006366 149 0.108
aromatic compound biosynthetic process GO:0019438 192 0.103
regulation of biological quality GO:0065008 741 0.103
organelle organization GO:0006996 783 0.100
transcription dna templated GO:0006351 168 0.098
mitotic nuclear envelope reassembly GO:0007084 3 0.098
negative regulation of cellular process GO:0048523 239 0.097
behavior GO:0007610 527 0.096
regulation of metabolic process GO:0019222 478 0.093
positive regulation of growth GO:0045927 369 0.093
single organism signaling GO:0044700 401 0.091
regulation of multicellular organism growth GO:0040014 373 0.091
gene expression GO:0010467 412 0.089
cellular component morphogenesis GO:0032989 318 0.088
positive regulation of multicellular organism growth GO:0040018 352 0.088
nucleic acid metabolic process GO:0090304 299 0.087
single organism localization GO:1902578 518 0.086
cell development GO:0048468 696 0.086
nuclear pore distribution GO:0031081 2 0.082
positive regulation of multicellular organismal process GO:0051240 417 0.082
signal transduction GO:0007165 317 0.081
organic cyclic compound biosynthetic process GO:1901362 195 0.080
post embryonic organ development GO:0048569 336 0.080
protein metabolic process GO:0019538 422 0.079
multi organism reproductive behavior GO:0044705 387 0.078
response to external stimulus GO:0009605 289 0.076
regulation of macromolecule biosynthetic process GO:0010556 189 0.075
anatomical structure formation involved in morphogenesis GO:0048646 250 0.075
biosynthetic process GO:0009058 323 0.074
regulation of nitrogen compound metabolic process GO:0051171 222 0.072
receptor mediated endocytosis GO:0006898 715 0.072
striated muscle cell development GO:0055002 157 0.071
nucleobase containing compound biosynthetic process GO:0034654 184 0.070
negative regulation of biological process GO:0048519 567 0.070
lipid localization GO:0010876 573 0.069
single organism organelle organization GO:1902589 501 0.069
cellular macromolecule biosynthetic process GO:0034645 247 0.069
lipid storage GO:0019915 565 0.068
meiotic cell cycle GO:0051321 335 0.068
multi organism reproductive process GO:0044703 867 0.068
oviposition GO:0018991 364 0.067
maintenance of location GO:0051235 580 0.066
reproductive behavior GO:0019098 387 0.065
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.064
regulation of rna biosynthetic process GO:2001141 165 0.063
negative regulation of metabolic process GO:0009892 240 0.063
regulation of multicellular organismal development GO:2000026 317 0.063
nervous system development GO:0007399 253 0.062
myofibril assembly GO:0030239 154 0.061
developmental growth GO:0048589 412 0.061
organic substance catabolic process GO:1901575 294 0.060
protein catabolic process GO:0030163 162 0.059
multi organism behavior GO:0051705 389 0.058
death GO:0016265 547 0.058
heterocycle biosynthetic process GO:0018130 187 0.057
striated muscle cell differentiation GO:0051146 158 0.057
regulation of gene expression GO:0010468 366 0.057
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.056
catabolic process GO:0009056 318 0.056
organelle assembly GO:0070925 214 0.055
ion transport GO:0006811 113 0.055
cuticle development GO:0042335 100 0.055
neurogenesis GO:0022008 236 0.055
neuron differentiation GO:0030182 217 0.054
negative regulation of multicellular organismal process GO:0051241 236 0.054
collagen and cuticulin based cuticle development GO:0040002 99 0.052
multicellular organism reproduction GO:0032504 819 0.051
axon development GO:0061564 163 0.051
positive regulation of gene expression GO:0010628 112 0.050
regulation of cellular metabolic process GO:0031323 305 0.050
multicellular organismal reproductive process GO:0048609 815 0.049
regulation of macromolecule metabolic process GO:0060255 421 0.048
vulval development GO:0040025 333 0.048
negative regulation of developmental process GO:0051093 227 0.048
macromolecule biosynthetic process GO:0009059 250 0.048
cytoskeleton organization GO:0007010 339 0.047
response to organic substance GO:0010033 131 0.047
embryonic morphogenesis GO:0048598 152 0.047
rna metabolic process GO:0016070 228 0.046
cellular macromolecular complex assembly GO:0034622 184 0.046
cellular component movement GO:0006928 388 0.045
establishment of localization in cell GO:0051649 318 0.045
multi multicellular organism process GO:0044706 390 0.045
cellular protein complex assembly GO:0043623 178 0.044
cell surface receptor signaling pathway GO:0007166 149 0.044
regulation of nucleic acid templated transcription GO:1903506 165 0.043
regulation of cellular biosynthetic process GO:0031326 189 0.042
regulation of cellular component size GO:0032535 40 0.042
cellular component biogenesis GO:0044085 297 0.042
generation of neurons GO:0048699 235 0.042
rna biosynthetic process GO:0032774 169 0.041
meiotic nuclear division GO:0007126 300 0.041
cellular component assembly involved in morphogenesis GO:0010927 183 0.040
defense response GO:0006952 296 0.039
small molecule metabolic process GO:0044281 186 0.039
regulation of transcription dna templated GO:0006355 164 0.037
er nucleus signaling pathway GO:0006984 66 0.036
muscle cell development GO:0055001 158 0.036
cellular localization GO:0051641 360 0.036
negative regulation of gene expression GO:0010629 217 0.035
cellular protein metabolic process GO:0044267 279 0.035
phagocytosis GO:0006909 115 0.035
macromolecular complex subunit organization GO:0043933 320 0.035
programmed cell death GO:0012501 500 0.035
purine nucleotide metabolic process GO:0006163 95 0.034
cellular nitrogen compound biosynthetic process GO:0044271 192 0.034
regulation of rna metabolic process GO:0051252 173 0.034
gene silencing GO:0016458 143 0.034
multicellular organismal reproductive behavior GO:0033057 384 0.033
organonitrogen compound metabolic process GO:1901564 151 0.033
cellular component assembly GO:0022607 293 0.033
regulation of primary metabolic process GO:0080090 292 0.033
response to wounding GO:0009611 4 0.032
macromolecule catabolic process GO:0009057 202 0.032
regulation of signaling GO:0023051 172 0.031
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.031
localization within membrane GO:0051668 2 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.031
cell cycle GO:0007049 526 0.031
negative regulation of cellular metabolic process GO:0031324 95 0.031
neuron projection development GO:0031175 187 0.030
cell fate commitment GO:0045165 139 0.030
cell projection organization GO:0030030 231 0.030
negative regulation of macromolecule metabolic process GO:0010605 229 0.030
regulation of cellular component organization GO:0051128 248 0.030
apoptotic process GO:0006915 478 0.029
muscle structure development GO:0061061 191 0.029
organophosphate metabolic process GO:0019637 125 0.029
head development GO:0060322 1 0.029
response to abiotic stimulus GO:0009628 152 0.029
nuclear pore localization GO:0051664 2 0.029
myosin filament assembly GO:0031034 138 0.028
protein complex biogenesis GO:0070271 186 0.028
striated muscle myosin thick filament assembly GO:0071688 138 0.028
response to topologically incorrect protein GO:0035966 82 0.028
anion transport GO:0006820 30 0.027
cellular response to stress GO:0033554 162 0.027
defense response to other organism GO:0098542 100 0.027
negative regulation of cellular component organization GO:0051129 33 0.026
protein complex subunit organization GO:0071822 280 0.026
digestive tract development GO:0048565 122 0.026
transmembrane transport GO:0055085 110 0.026
muscle cell differentiation GO:0042692 171 0.026
nematode male tail tip morphogenesis GO:0045138 77 0.026
male sex differentiation GO:0046661 86 0.026
nucleoside monophosphate metabolic process GO:0009123 46 0.026
regulation of signal transduction GO:0009966 135 0.026
actomyosin structure organization GO:0031032 154 0.025
phosphorus metabolic process GO:0006793 232 0.025
positive regulation of metabolic process GO:0009893 187 0.025
regulation of nervous system development GO:0051960 41 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.024
cellular response to topologically incorrect protein GO:0035967 76 0.024
protein complex assembly GO:0006461 186 0.023
purine nucleotide catabolic process GO:0006195 75 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.023
digestive system development GO:0055123 122 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.023
neuron development GO:0048666 199 0.023
localization of cell GO:0051674 313 0.023
sexual reproduction GO:0019953 546 0.022
ribonucleotide catabolic process GO:0009261 75 0.022
pattern specification process GO:0007389 59 0.022
regulation of gene expression epigenetic GO:0040029 163 0.022
myosin filament organization GO:0031033 138 0.021
chromosome segregation GO:0007059 180 0.021
cell proliferation GO:0008283 116 0.021
positive regulation of macromolecule metabolic process GO:0010604 149 0.021
cell migration GO:0016477 306 0.021
cell cycle process GO:0022402 482 0.021
negative regulation of rna biosynthetic process GO:1902679 53 0.021
actin cytoskeleton organization GO:0030036 184 0.021
negative regulation of gene expression epigenetic GO:0045814 2 0.021
regulation of cell communication GO:0010646 176 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.020
purine ribonucleotide metabolic process GO:0009150 95 0.020
cell death GO:0008219 547 0.020
positive regulation of rna metabolic process GO:0051254 103 0.020
germ cell development GO:0007281 351 0.020
regulation of cell cycle GO:0051726 194 0.020
cell motility GO:0048870 313 0.020
male anatomical structure morphogenesis GO:0090598 78 0.020
ribose phosphate metabolic process GO:0019693 99 0.019
ion transmembrane transport GO:0034220 91 0.019
atp metabolic process GO:0046034 42 0.019
digestive tract morphogenesis GO:0048546 76 0.019
membrane organization GO:0061024 135 0.018
nuclear envelope reassembly GO:0031468 4 0.018
ribonucleoside triphosphate metabolic process GO:0009199 87 0.018
actin filament based process GO:0030029 191 0.018
regulation of biosynthetic process GO:0009889 189 0.018
negative regulation of nucleic acid templated transcription GO:1903507 53 0.018
cell division GO:0051301 262 0.018
nucleus organization GO:0006997 38 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.017
regulation of locomotion GO:0040012 161 0.017
embryonic body morphogenesis GO:0010172 49 0.017
tube development GO:0035295 126 0.017
negative regulation of rna metabolic process GO:0051253 53 0.016
female gamete generation GO:0007292 254 0.016
response to external biotic stimulus GO:0043207 101 0.016
macromolecular complex assembly GO:0065003 193 0.016
apoptotic mitochondrial changes GO:0008637 2 0.016
negative regulation of response to stimulus GO:0048585 73 0.016
cell morphogenesis involved in differentiation GO:0000904 112 0.016
skeletal muscle organ development GO:0060538 3 0.016
tissue development GO:0009888 112 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
feeding behavior GO:0007631 70 0.016
microtubule based process GO:0007017 182 0.015
neuron projection morphogenesis GO:0048812 114 0.015
secretion by cell GO:0032940 138 0.015
regulation of organelle organization GO:0033043 164 0.015
negative regulation of transcription dna templated GO:0045892 53 0.015
nucleobase containing compound catabolic process GO:0034655 114 0.015
positive regulation of nucleic acid templated transcription GO:1903508 102 0.015
carbohydrate derivative metabolic process GO:1901135 141 0.015
membrane invagination GO:0010324 98 0.015
ribonucleoside catabolic process GO:0042454 77 0.015
regulation of localization GO:0032879 194 0.015
ribonucleotide metabolic process GO:0009259 99 0.014
carbohydrate derivative catabolic process GO:1901136 82 0.014
organ morphogenesis GO:0009887 67 0.014
intracellular transport GO:0046907 77 0.014
negative regulation of cellular biosynthetic process GO:0031327 65 0.014
nucleoside catabolic process GO:0009164 78 0.014
cellular protein modification process GO:0006464 207 0.014
secretion GO:0046903 147 0.014
purine ribonucleoside metabolic process GO:0046128 92 0.014
gamete generation GO:0007276 461 0.014
positive regulation of rna biosynthetic process GO:1902680 102 0.014
taxis GO:0042330 128 0.013
regeneration GO:0031099 4 0.013
mitochondrion organization GO:0007005 20 0.013
cellular protein complex localization GO:0034629 3 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
cell recognition GO:0008037 85 0.013
response to acid chemical GO:0001101 4 0.013
response to oxygen containing compound GO:1901700 44 0.013
response to bacterium GO:0009617 86 0.013
regulation of cell cycle process GO:0010564 145 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
epithelial cell proliferation GO:0050673 1 0.013
cellular macromolecule localization GO:0070727 75 0.012
inductive cell migration GO:0040039 145 0.012
chemotaxis GO:0006935 120 0.012
defense response to gram negative bacterium GO:0050829 64 0.012
single organism biosynthetic process GO:0044711 91 0.012
phagocytosis engulfment GO:0006911 98 0.012
axonal fasciculation GO:0007413 79 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
engulfment of apoptotic cell GO:0043652 94 0.012
ribonucleoside metabolic process GO:0009119 98 0.012
endoplasmic reticulum unfolded protein response GO:0030968 66 0.012
heterocycle catabolic process GO:0046700 119 0.012
adult behavior GO:0030534 3 0.012
regulation of mitochondrion organization GO:0010821 1 0.012
protein modification process GO:0036211 207 0.012
oogenesis GO:0048477 229 0.012
regulation of lipid transport GO:0032368 4 0.012
purine nucleoside triphosphate catabolic process GO:0009146 72 0.012
tissue morphogenesis GO:0048729 65 0.011
response to endoplasmic reticulum stress GO:0034976 71 0.011
tube morphogenesis GO:0035239 79 0.011
sensory organ morphogenesis GO:0090596 2 0.011
adult locomotory behavior GO:0008344 1 0.011
purine containing compound metabolic process GO:0072521 95 0.011
nucleoside metabolic process GO:0009116 99 0.011
neuron recognition GO:0008038 83 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
muscle system process GO:0003012 43 0.011
regulation of cell proliferation GO:0042127 105 0.011
regulation of neurogenesis GO:0050767 40 0.011
positive regulation of cellular process GO:0048522 332 0.011
regulation of post embryonic development GO:0048580 260 0.011
regulation of response to wounding GO:1903034 1 0.011
system process GO:0003008 136 0.010
glycosyl compound metabolic process GO:1901657 100 0.010
cellular response to unfolded protein GO:0034620 71 0.010
oxoacid metabolic process GO:0043436 47 0.010
cellular nitrogen compound catabolic process GO:0044270 119 0.010
neuron projection guidance GO:0097485 82 0.010
muscle attachment GO:0016203 3 0.010
organic acid metabolic process GO:0006082 47 0.010
muscle organ development GO:0007517 26 0.010
regulation of cell development GO:0060284 49 0.010
ribonucleoside monophosphate metabolic process GO:0009161 45 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.010

amx-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.078
muscular disease DOID:0080000 0 0.078
heart disease DOID:114 0 0.078
cardiomyopathy DOID:0050700 0 0.078
disease of anatomical entity DOID:7 0 0.078
cardiovascular system disease DOID:1287 0 0.078
musculoskeletal system disease DOID:17 0 0.078
muscle tissue disease DOID:66 0 0.078
congenital muscular dystrophy DOID:0050557 0 0.073
muscular dystrophy DOID:9884 0 0.073
dilated cardiomyopathy DOID:12930 0 0.066
intrinsic cardiomyopathy DOID:0060036 0 0.066
progeria DOID:3911 0 0.043
lipodystrophy DOID:811 0 0.035
skin disease DOID:37 0 0.035
integumentary system disease DOID:16 0 0.035
familial partial lipodystrophy DOID:0050440 0 0.035
emery dreifuss muscular dystrophy DOID:11726 0 0.020
nervous system disease DOID:863 0 0.018
neuromuscular disease DOID:440 0 0.017
charcot marie tooth disease type 2 DOID:0050539 0 0.017
charcot marie tooth disease DOID:10595 0 0.017
neuropathy DOID:870 0 0.017
limb girdle muscular dystrophy DOID:11724 0 0.012
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010