Caenorhabditis elegans

25 known processes

aldo-2 (CELE_F01F1.12)

Protein ALDO-2

aldo-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ development GO:0048513 1102 0.372
Zebrafish
multicellular organismal reproductive process GO:0048609 815 0.327
establishment of localization GO:0051234 1171 0.312
cell death GO:0008219 547 0.233
oxoacid metabolic process GO:0043436 47 0.212
Human
cellular localization GO:0051641 360 0.187
transport GO:0006810 1093 0.171
negative regulation of biological process GO:0048519 567 0.152
small molecule metabolic process GO:0044281 186 0.149
Human
cell motility GO:0048870 313 0.145
developmental process involved in reproduction GO:0003006 1165 0.142
determination of adult lifespan GO:0008340 812 0.137
behavior GO:0007610 527 0.129
embryo development GO:0009790 3052 0.128
organophosphate ester transport GO:0015748 5 0.127
reproductive structure development GO:0048608 850 0.125
multicellular organism reproduction GO:0032504 819 0.124
gonad development GO:0008406 840 0.122
defense response GO:0006952 296 0.117
cell development GO:0048468 696 0.117
Zebrafish
localization of cell GO:0051674 313 0.116
macromolecule localization GO:0033036 771 0.115
signaling GO:0023052 401 0.114
sex differentiation GO:0007548 909 0.112
aging GO:0007568 812 0.109
single organism reproductive process GO:0044702 1196 0.109
reproductive behavior GO:0019098 387 0.102
signal transduction GO:0007165 317 0.100
organic acid metabolic process GO:0006082 47 0.100
Human
multicellular organismal aging GO:0010259 812 0.100
reproductive system development GO:0061458 850 0.098
monocarboxylic acid metabolic process GO:0032787 22 0.095
Human
single organism signaling GO:0044700 401 0.093
multi organism reproductive process GO:0044703 867 0.092
single organism transport GO:0044765 447 0.090
regulation of biological quality GO:0065008 741 0.087
Human
ion transport GO:0006811 113 0.086
single organism localization GO:1902578 518 0.085
multicellular organismal reproductive behavior GO:0033057 384 0.084
locomotion GO:0040011 1634 0.083
regulation of transport GO:0051049 91 0.079
cell migration GO:0016477 306 0.079
lipid storage GO:0019915 565 0.076
lipid localization GO:0010876 573 0.076
multi organism behavior GO:0051705 389 0.074
embryo development ending in birth or egg hatching GO:0009792 2992 0.073
maintenance of location GO:0051235 580 0.072
multi organism reproductive behavior GO:0044705 387 0.072
carboxylic acid metabolic process GO:0019752 34 0.072
Human
death GO:0016265 547 0.071
gene expression GO:0010467 412 0.071
regulation of metabolic process GO:0019222 478 0.071
anatomical structure formation involved in morphogenesis GO:0048646 250 0.071
Zebrafish
oviposition GO:0018991 364 0.069
male sex differentiation GO:0046661 86 0.066
regulation of localization GO:0032879 194 0.064
multi multicellular organism process GO:0044706 390 0.063
gamete generation GO:0007276 461 0.063
vulval development GO:0040025 333 0.060
phosphorus metabolic process GO:0006793 232 0.060
Human
regulation of multi organism process GO:0043900 69 0.060
post embryonic development GO:0009791 2152 0.058
development of primary sexual characteristics GO:0045137 840 0.058
female gamete generation GO:0007292 254 0.057
regulation of locomotion GO:0040012 161 0.056
receptor mediated endocytosis GO:0006898 715 0.055
regulation of reproductive process GO:2000241 66 0.053
endocytosis GO:0006897 819 0.053
response to wounding GO:0009611 4 0.053
membrane organization GO:0061024 135 0.051
regulation of signaling GO:0023051 172 0.051
regulation of multicellular organismal process GO:0051239 726 0.051
regulation of signal transduction GO:0009966 135 0.051
biosynthetic process GO:0009058 323 0.051
Human
cellular component movement GO:0006928 388 0.050
small molecule biosynthetic process GO:0044283 38 0.049
regulation of cellular localization GO:0060341 42 0.049
development of primary male sexual characteristics GO:0046546 4 0.048
germ cell development GO:0007281 351 0.048
organic substance biosynthetic process GO:1901576 323 0.047
Human
regulation of cell communication GO:0010646 176 0.047
regulation of multicellular organismal development GO:2000026 317 0.044
intracellular transport GO:0046907 77 0.044
transmembrane transport GO:0055085 110 0.043
response to other organism GO:0051707 101 0.041
regulation of protein import into nucleus GO:0042306 3 0.040
regulation of protein localization GO:0032880 50 0.040
organonitrogen compound metabolic process GO:1901564 151 0.039
Human
organelle assembly GO:0070925 214 0.039
atp biosynthetic process GO:0006754 4 0.039
Human
cell cell signaling GO:0007267 118 0.038
growth GO:0040007 562 0.038
response to abiotic stimulus GO:0009628 152 0.038
innate immune response GO:0045087 190 0.038
response to biotic stimulus GO:0009607 101 0.037
negative regulation of multicellular organismal process GO:0051241 236 0.037
nitrogen compound transport GO:0071705 49 0.037
negative regulation of post embryonic development GO:0048581 208 0.036
regulation of gene expression GO:0010468 366 0.036
single organism catabolic process GO:0044712 129 0.036
Human
post embryonic organ development GO:0048569 336 0.036
response to external stimulus GO:0009605 289 0.035
Zebrafish
regulation of nucleocytoplasmic transport GO:0046822 3 0.035
positive regulation of growth GO:0045927 369 0.035
positive regulation of signaling GO:0023056 66 0.035
negative regulation of gene expression GO:0010629 217 0.035
cellular component assembly involved in morphogenesis GO:0010927 183 0.035
negative regulation of vulval development GO:0040027 206 0.034
myofibril assembly GO:0030239 154 0.034
organonitrogen compound biosynthetic process GO:1901566 44 0.034
Human
regulation of rna biosynthetic process GO:2001141 165 0.034
intracellular receptor signaling pathway GO:0030522 2 0.033
purine ribonucleoside monophosphate biosynthetic process GO:0009168 4 0.033
Human
establishment of localization in cell GO:0051649 318 0.033
organic substance transport GO:0071702 113 0.033
organelle organization GO:0006996 783 0.033
cellular protein complex assembly GO:0043623 178 0.032
system process GO:0003008 136 0.032
Human
catabolic process GO:0009056 318 0.032
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.032
cellular response to chemical stimulus GO:0070887 129 0.030
regulation of nematode larval development GO:0061062 260 0.030
response to external biotic stimulus GO:0043207 101 0.030
single organism organelle organization GO:1902589 501 0.030
nucleobase containing compound biosynthetic process GO:0034654 184 0.030
Human
actin cytoskeleton organization GO:0030036 184 0.030
regulation of cell cycle GO:0051726 194 0.030
protein complex subunit organization GO:0071822 280 0.030
positive regulation of developmental growth GO:0048639 354 0.030
lipid metabolic process GO:0006629 77 0.029
cellular biosynthetic process GO:0044249 315 0.029
Human
immune response GO:0006955 192 0.029
muscle cell differentiation GO:0042692 171 0.029
regulation of growth GO:0040008 409 0.029
positive regulation of intracellular signal transduction GO:1902533 24 0.029
defense response to bacterium GO:0042742 86 0.028
actin filament based process GO:0030029 191 0.028
cellular component biogenesis GO:0044085 297 0.028
protein complex biogenesis GO:0070271 186 0.028
oxidation reduction process GO:0055114 59 0.027
programmed cell death GO:0012501 500 0.027
regulation of cytoplasmic transport GO:1903649 3 0.026
response to inorganic substance GO:0010035 50 0.026
molting cycle GO:0042303 281 0.026
regulation of biosynthetic process GO:0009889 189 0.026
positive regulation of multicellular organismal process GO:0051240 417 0.026
cellular macromolecular complex assembly GO:0034622 184 0.026
single organism biosynthetic process GO:0044711 91 0.026
Human
nucleobase containing compound metabolic process GO:0006139 406 0.025
Human
myosin filament assembly GO:0031034 138 0.025
actomyosin structure organization GO:0031032 154 0.025
ribonucleoside triphosphate biosynthetic process GO:0009201 4 0.025
Human
regulation of epithelial cell proliferation GO:0050678 1 0.025
muscle structure development GO:0061061 191 0.024
cation transport GO:0006812 78 0.024
positive regulation of phosphorus metabolic process GO:0010562 56 0.024
organic substance catabolic process GO:1901575 294 0.024
Human
vesicle mediated transport GO:0016192 852 0.024
aromatic compound biosynthetic process GO:0019438 192 0.024
Human
cellular protein metabolic process GO:0044267 279 0.024
response to bacterium GO:0009617 86 0.023
positive regulation of developmental process GO:0051094 408 0.023
oogenesis GO:0048477 229 0.023
apoptotic cell clearance GO:0043277 111 0.023
regulation of multicellular organism growth GO:0040014 373 0.023
regulation of macromolecule metabolic process GO:0060255 421 0.022
cell surface receptor signaling pathway GO:0007166 149 0.022
cellular component assembly GO:0022607 293 0.022
regulation of phosphorylation GO:0042325 45 0.022
myosin filament organization GO:0031033 138 0.021
regulation of vulval development GO:0040028 248 0.021
negative regulation of cellular process GO:0048523 239 0.021
positive regulation of neurogenesis GO:0050769 4 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
single organism intracellular transport GO:1902582 70 0.020
developmental growth GO:0048589 412 0.020
phosphorylation GO:0016310 116 0.020
cellular response to organic substance GO:0071310 119 0.020
fatty acid biosynthetic process GO:0006633 10 0.020
peptidyl amino acid modification GO:0018193 58 0.020
cell type specific apoptotic process GO:0097285 4 0.020
striated muscle myosin thick filament assembly GO:0071688 138 0.020
positive regulation of phosphorylation GO:0042327 27 0.020
body morphogenesis GO:0010171 620 0.020
cellular response to inorganic substance GO:0071241 3 0.020
apoptotic process GO:0006915 478 0.019
epithelial cell proliferation GO:0050673 1 0.019
positive regulation of cell communication GO:0010647 69 0.019
rna metabolic process GO:0016070 228 0.019
cellular amino acid metabolic process GO:0006520 15 0.019
macromolecule modification GO:0043412 218 0.018
adult behavior GO:0030534 3 0.018
hormone transport GO:0009914 2 0.018
regulation of cell motility GO:2000145 57 0.018
regulation of protein targeting GO:1903533 3 0.018
heterocycle biosynthetic process GO:0018130 187 0.018
Human
positive regulation of phosphate metabolic process GO:0045937 56 0.018
muscle cell development GO:0055001 158 0.018
sexual reproduction GO:0019953 546 0.018
macromolecular complex subunit organization GO:0043933 320 0.018
meiotic cell cycle GO:0051321 335 0.018
protein metabolic process GO:0019538 422 0.018
protein phosphorylation GO:0006468 85 0.018
carboxylic acid biosynthetic process GO:0046394 21 0.018
response to chemical GO:0042221 356 0.018
regulation of molecular function GO:0065009 89 0.018
generation of neurons GO:0048699 235 0.018
Zebrafish
regulation of developmental growth GO:0048638 389 0.017
purine nucleoside monophosphate biosynthetic process GO:0009127 4 0.017
Human
regulation of lipid metabolic process GO:0019216 4 0.017
regulation of nucleic acid templated transcription GO:1903506 165 0.017
single organism behavior GO:0044708 83 0.017
striated muscle cell development GO:0055002 157 0.017
negative regulation of macromolecule metabolic process GO:0010605 229 0.017
nucleic acid metabolic process GO:0090304 299 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.016
mapk cascade GO:0000165 31 0.016
regulation of response to stimulus GO:0048583 243 0.016
organelle fission GO:0048285 363 0.016
regulation of response to wounding GO:1903034 1 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
negative regulation of nematode larval development GO:0061064 208 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
Human
positive regulation of transport GO:0051050 32 0.016
single organism carbohydrate metabolic process GO:0044723 29 0.016
Human
negative regulation of metabolic process GO:0009892 240 0.016
regulation of post embryonic development GO:0048580 260 0.015
negative regulation of developmental process GO:0051093 227 0.015
cellular macromolecule biosynthetic process GO:0034645 247 0.015
response to temperature stimulus GO:0009266 66 0.015
protein complex assembly GO:0006461 186 0.015
regulation of cellular component movement GO:0051270 62 0.015
regulation of cellular catabolic process GO:0031329 51 0.015
protein localization GO:0008104 205 0.015
regulation of organelle organization GO:0033043 164 0.015
defense response to gram negative bacterium GO:0050829 64 0.014
positive regulation of metabolic process GO:0009893 187 0.014
organic cyclic compound biosynthetic process GO:1901362 195 0.014
Human
regulation of developmental process GO:0050793 684 0.014
Human
regulation of cellular component organization GO:0051128 248 0.014
Human
multicellular organism growth GO:0035264 385 0.014
phagocytosis engulfment GO:0006911 98 0.014
regulation of meiotic cell cycle GO:0051445 136 0.014
defense response to other organism GO:0098542 100 0.014
protein modification process GO:0036211 207 0.014
lipid oxidation GO:0034440 1 0.014
synaptic transmission GO:0007268 106 0.014
meiotic nuclear division GO:0007126 300 0.013
positive regulation of multicellular organism growth GO:0040018 352 0.013
regulation of cellular metabolic process GO:0031323 305 0.013
regulation of oviposition GO:0046662 43 0.013
regulation of transcription dna templated GO:0006355 164 0.013
cellular response to oxygen containing compound GO:1901701 21 0.013
positive regulation of mapk cascade GO:0043410 14 0.013
cellular protein modification process GO:0006464 207 0.013
neurological system process GO:0050877 53 0.013
peptide hormone secretion GO:0030072 2 0.013
response to oxidative stress GO:0006979 42 0.013
regulation of nucleoside metabolic process GO:0009118 37 0.013
cytoskeleton organization GO:0007010 339 0.013
protein oligomerization GO:0051259 4 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
negative regulation of response to external stimulus GO:0032102 3 0.013
regulation of hormone secretion GO:0046883 2 0.013
cell proliferation GO:0008283 116 0.013
cellular catabolic process GO:0044248 199 0.012
regulation of lipid biosynthetic process GO:0046890 1 0.012
cellular ketone metabolic process GO:0042180 14 0.012
cellular response to abiotic stimulus GO:0071214 4 0.012
response to organic substance GO:0010033 131 0.012
internal peptidyl lysine acetylation GO:0018393 3 0.012
secretion by cell GO:0032940 138 0.012
transcription from rna polymerase ii promoter GO:0006366 149 0.012
rna interference GO:0016246 137 0.012
ion transmembrane transport GO:0034220 91 0.012
gene silencing GO:0016458 143 0.012
genitalia development GO:0048806 741 0.012
regulation of mitochondrion organization GO:0010821 1 0.012
amine metabolic process GO:0009308 15 0.012
gene silencing by rna GO:0031047 143 0.011
cuticle development GO:0042335 100 0.011
positive regulation of cellular metabolic process GO:0031325 178 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
neuromuscular junction development GO:0007528 2 0.011
regeneration GO:0031099 4 0.011
membrane invagination GO:0010324 98 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
apoptotic mitochondrial changes GO:0008637 2 0.011
response to heat GO:0009408 50 0.011
macromolecule biosynthetic process GO:0009059 250 0.011
regulation of phosphate metabolic process GO:0019220 81 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.011
engulfment of apoptotic cell GO:0043652 94 0.011
regulation of mapk cascade GO:0043408 23 0.011
macromolecular complex assembly GO:0065003 193 0.011
response to oxygen containing compound GO:1901700 44 0.011
adult locomotory behavior GO:0008344 1 0.011
phagocytosis GO:0006909 115 0.011
anion transport GO:0006820 30 0.011
insulin secretion GO:0030073 2 0.011
detection of external stimulus GO:0009581 4 0.011
posttranscriptional gene silencing GO:0016441 143 0.011
chemical homeostasis GO:0048878 29 0.011
purine nucleoside biosynthetic process GO:0042451 5 0.010
Human
regulation of cell differentiation GO:0045595 81 0.010
fatty acid oxidation GO:0019395 1 0.010
nucleoside triphosphate biosynthetic process GO:0009142 4 0.010
Human
protein transport GO:0015031 45 0.010
organic cyclic compound catabolic process GO:1901361 119 0.010
cellular response to endogenous stimulus GO:0071495 32 0.010
detection of abiotic stimulus GO:0009582 4 0.010
alpha amino acid metabolic process GO:1901605 10 0.010

aldo-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.027
inherited metabolic disorder DOID:655 0 0.022
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.015