Caenorhabditis elegans

119 known processes

daf-8 (CELE_R05D11.1)

Protein DAF-8

daf-8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 1634 0.137
Worm
embryo development GO:0009790 3052 0.125
post embryonic development GO:0009791 2152 0.122
embryo development ending in birth or egg hatching GO:0009792 2992 0.088
aging GO:0007568 812 0.087
multicellular organismal aging GO:0010259 812 0.084
body morphogenesis GO:0010171 620 0.083
Worm
macromolecule localization GO:0033036 771 0.079
determination of adult lifespan GO:0008340 812 0.077
maintenance of location GO:0051235 580 0.064
regulation of biological quality GO:0065008 741 0.063
Worm
cellular localization GO:0051641 360 0.062
regulation of multicellular organismal process GO:0051239 726 0.060
Worm
regulation of developmental process GO:0050793 684 0.059
Worm
lipid storage GO:0019915 565 0.057
single organism localization GO:1902578 518 0.057
positive regulation of growth GO:0045927 369 0.055
Worm
lipid localization GO:0010876 573 0.055
organelle organization GO:0006996 783 0.054
sex differentiation GO:0007548 909 0.054
Worm
apoptotic process GO:0006915 478 0.052
multicellular organism growth GO:0035264 385 0.052
Worm
developmental growth GO:0048589 412 0.051
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.051
Worm
positive regulation of developmental process GO:0051094 408 0.051
Worm
single organism reproductive process GO:0044702 1196 0.050
cell death GO:0008219 547 0.050
multi organism reproductive process GO:0044703 867 0.049
positive regulation of developmental growth GO:0048639 354 0.049
Worm
death GO:0016265 547 0.048
multicellular organismal reproductive process GO:0048609 815 0.048
developmental process involved in reproduction GO:0003006 1165 0.048
Worm
regulation of growth GO:0040008 409 0.048
Worm
post embryonic organ development GO:0048569 336 0.044
Worm
regulation of multicellular organism growth GO:0040014 373 0.044
Worm
growth GO:0040007 562 0.043
Worm
cell cycle GO:0007049 526 0.042
Worm
cell development GO:0048468 696 0.042
positive regulation of multicellular organism growth GO:0040018 352 0.041
Worm
regulation of developmental growth GO:0048638 389 0.040
Worm
defense response to fungus GO:0050832 19 0.039
Worm
transport GO:0006810 1093 0.038
cell cycle process GO:0022402 482 0.038
Worm
regulation of metabolic process GO:0019222 478 0.038
head development GO:0060322 1 0.038
sexual reproduction GO:0019953 546 0.037
vesicle mediated transport GO:0016192 852 0.037
behavior GO:0007610 527 0.037
protein metabolic process GO:0019538 422 0.037
Worm
organ development GO:0048513 1102 0.036
Worm
programmed cell death GO:0012501 500 0.036
multi organism reproductive behavior GO:0044705 387 0.035
single organism organelle organization GO:1902589 501 0.035
cellular component movement GO:0006928 388 0.035
vulval development GO:0040025 333 0.035
Worm
protein complex subunit organization GO:0071822 280 0.034
localization of cell GO:0051674 313 0.034
catabolic process GO:0009056 318 0.033
Worm
cytoskeleton organization GO:0007010 339 0.033
response to wounding GO:0009611 4 0.033
establishment of localization GO:0051234 1171 0.033
phosphorus metabolic process GO:0006793 232 0.032
establishment of localization in cell GO:0051649 318 0.032
single organism signaling GO:0044700 401 0.031
Worm
small molecule metabolic process GO:0044281 186 0.031
gamete generation GO:0007276 461 0.031
hermaphrodite genitalia development GO:0040035 734 0.031
cellular component morphogenesis GO:0032989 318 0.031
multi multicellular organism process GO:0044706 390 0.031
defense response GO:0006952 296 0.031
multicellular organism reproduction GO:0032504 819 0.031
regulation of bmp signaling pathway GO:0030510 3 0.030
regulation of post embryonic development GO:0048580 260 0.030
Worm
macromolecular complex subunit organization GO:0043933 320 0.030
nucleic acid metabolic process GO:0090304 299 0.030
gene expression GO:0010467 412 0.030
multi organism behavior GO:0051705 389 0.030
immune response GO:0006955 192 0.029
Worm
cell division GO:0051301 262 0.029
organic acid metabolic process GO:0006082 47 0.029
organonitrogen compound metabolic process GO:1901564 151 0.028
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.028
oxoacid metabolic process GO:0043436 47 0.028
innate immune response GO:0045087 190 0.028
Worm
reproductive structure development GO:0048608 850 0.028
biosynthetic process GO:0009058 323 0.028
reproductive behavior GO:0019098 387 0.028
negative regulation of bmp signaling pathway GO:0030514 1 0.028
nucleobase containing compound metabolic process GO:0006139 406 0.028
regulation of gene expression GO:0010468 366 0.027
axon development GO:0061564 163 0.027
positive regulation of cellular metabolic process GO:0031325 178 0.027
multicellular organismal reproductive behavior GO:0033057 384 0.026
molting cycle GO:0042303 281 0.026
regulation of cellular ketone metabolic process GO:0010565 3 0.026
organic substance catabolic process GO:1901575 294 0.026
Worm
cellular component biogenesis GO:0044085 297 0.026
regulation of multicellular organismal development GO:2000026 317 0.025
Worm
endocytosis GO:0006897 819 0.025
signaling GO:0023052 401 0.025
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.025
actin cytoskeleton organization GO:0030036 184 0.024
meiotic cell cycle GO:0051321 335 0.024
Worm
response to external stimulus GO:0009605 289 0.024
receptor mediated endocytosis GO:0006898 715 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.024
membrane organization GO:0061024 135 0.023
genitalia development GO:0048806 741 0.023
response to chemical GO:0042221 356 0.023
regulation of macromolecule metabolic process GO:0060255 421 0.023
single organism transport GO:0044765 447 0.022
nucleoside phosphate metabolic process GO:0006753 108 0.022
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.022
cellular component assembly GO:0022607 293 0.022
neuron differentiation GO:0030182 217 0.022
reproductive system development GO:0061458 850 0.022
cellular protein complex assembly GO:0043623 178 0.022
organelle fission GO:0048285 363 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
regulation of organ morphogenesis GO:2000027 4 0.022
cell type specific apoptotic process GO:0097285 4 0.022
nervous system development GO:0007399 253 0.022
gonad development GO:0008406 840 0.021
regulation of cytoplasmic transport GO:1903649 3 0.021
protein localization GO:0008104 205 0.021
carboxylic acid metabolic process GO:0019752 34 0.021
development of primary sexual characteristics GO:0045137 840 0.021
regulation of cellular component organization GO:0051128 248 0.021
organic substance biosynthetic process GO:1901576 323 0.021
generation of neurons GO:0048699 235 0.021
taxis GO:0042330 128 0.021
negative regulation of gene expression GO:0010629 217 0.021
neurogenesis GO:0022008 236 0.021
negative regulation of biological process GO:0048519 567 0.020
cellular ketone metabolic process GO:0042180 14 0.020
positive regulation of cellular process GO:0048522 332 0.020
oviposition GO:0018991 364 0.020
neuron development GO:0048666 199 0.020
regulation of signaling GO:0023051 172 0.020
carbohydrate derivative metabolic process GO:1901135 141 0.020
cell motility GO:0048870 313 0.019
regulation of cellular metabolic process GO:0031323 305 0.019
regulation of lipid metabolic process GO:0019216 4 0.019
neuron projection development GO:0031175 187 0.019
cellular catabolic process GO:0044248 199 0.019
purine nucleotide metabolic process GO:0006163 95 0.019
male anatomical structure morphogenesis GO:0090598 78 0.019
Worm
cell projection organization GO:0030030 231 0.019
cellular response to abiotic stimulus GO:0071214 4 0.019
purine ribonucleoside metabolic process GO:0046128 92 0.018
response to bacterium GO:0009617 86 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
positive regulation of catalytic activity GO:0043085 59 0.018
negative regulation of developmental process GO:0051093 227 0.018
Worm
macromolecule biosynthetic process GO:0009059 250 0.018
phosphate containing compound metabolic process GO:0006796 232 0.018
response to biotic stimulus GO:0009607 101 0.018
macromolecular complex assembly GO:0065003 193 0.018
regulation of vulval development GO:0040028 248 0.018
Worm
dauer larval development GO:0040024 92 0.018
posttranscriptional gene silencing GO:0016441 143 0.018
signal transduction GO:0007165 317 0.018
Worm
mitotic cell cycle process GO:1903047 194 0.018
single organism intracellular transport GO:1902582 70 0.018
ribonucleoside metabolic process GO:0009119 98 0.018
organophosphate metabolic process GO:0019637 125 0.017
establishment of organelle localization GO:0051656 123 0.017
glycosyl compound metabolic process GO:1901657 100 0.017
posttranscriptional gene silencing by rna GO:0035194 143 0.017
cellular macromolecule biosynthetic process GO:0034645 247 0.017
defense response to other organism GO:0098542 100 0.017
regulation of cell communication GO:0010646 176 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
gene silencing by rna GO:0031047 143 0.017
cellular biosynthetic process GO:0044249 315 0.017
cellular protein modification process GO:0006464 207 0.017
protein complex assembly GO:0006461 186 0.017
regulation of primary metabolic process GO:0080090 292 0.017
cellular response to chemical stimulus GO:0070887 129 0.017
male sex differentiation GO:0046661 86 0.017
Worm
defense response to gram negative bacterium GO:0050829 64 0.017
response to other organism GO:0051707 101 0.017
cell morphogenesis GO:0000902 163 0.017
actin filament based process GO:0030029 191 0.017
positive regulation of metabolic process GO:0009893 187 0.017
organelle localization GO:0051640 127 0.017
germ cell development GO:0007281 351 0.016
nucleic acid templated transcription GO:0097659 169 0.016
cell projection morphogenesis GO:0048858 148 0.016
intracellular signal transduction GO:0035556 96 0.016
Worm
bmp signaling pathway GO:0030509 3 0.016
nucleobase containing small molecule metabolic process GO:0055086 115 0.016
positive regulation of cellular biosynthetic process GO:0031328 109 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.016
sensory organ morphogenesis GO:0090596 2 0.016
secretion GO:0046903 147 0.016
cell migration GO:0016477 306 0.016
single organism catabolic process GO:0044712 129 0.016
positive regulation of catabolic process GO:0009896 38 0.016
Worm
negative regulation of macromolecule metabolic process GO:0010605 229 0.016
regulation of cell cycle GO:0051726 194 0.016
Worm
nucleoside metabolic process GO:0009116 99 0.016
cellular macromolecular complex assembly GO:0034622 184 0.015
rna interference GO:0016246 137 0.015
secretion by cell GO:0032940 138 0.015
negative regulation of multicellular organismal process GO:0051241 236 0.015
Worm
cellular amino acid metabolic process GO:0006520 15 0.015
nucleobase containing compound biosynthetic process GO:0034654 184 0.015
regulation of nucleocytoplasmic transport GO:0046822 3 0.015
positive regulation of rna biosynthetic process GO:1902680 102 0.015
heterocycle catabolic process GO:0046700 119 0.015
protein catabolic process GO:0030163 162 0.015
Worm
chromosome organization GO:0051276 104 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
nucleotide metabolic process GO:0009117 108 0.015
axonogenesis GO:0007409 102 0.015
regulation of rna biosynthetic process GO:2001141 165 0.015
positive regulation of cell migration GO:0030335 3 0.015
muscle structure development GO:0061061 191 0.015
organic substance transport GO:0071702 113 0.015
regulation of cellular biosynthetic process GO:0031326 189 0.015
response to abiotic stimulus GO:0009628 152 0.015
chemotaxis GO:0006935 120 0.015
cytokinesis GO:0000910 80 0.015
protein complex biogenesis GO:0070271 186 0.015
apoptotic cell clearance GO:0043277 111 0.014
organelle assembly GO:0070925 214 0.014
cellular macromolecule localization GO:0070727 75 0.014
posttranscriptional regulation of gene expression GO:0010608 166 0.014
cellular protein metabolic process GO:0044267 279 0.014
ribose phosphate metabolic process GO:0019693 99 0.014
neuron projection guidance GO:0097485 82 0.014
amine metabolic process GO:0009308 15 0.014
negative regulation of cellular process GO:0048523 239 0.014
intracellular transport GO:0046907 77 0.014
regulation of gene expression epigenetic GO:0040029 163 0.014
muscle tissue development GO:0060537 1 0.014
meiotic cell cycle process GO:1903046 170 0.014
positive regulation of gene expression GO:0010628 112 0.014
regulation of epithelial cell proliferation GO:0050678 1 0.014
cellular amine metabolic process GO:0044106 15 0.014
axon guidance GO:0007411 82 0.014
negative regulation of metabolic process GO:0009892 240 0.014
epithelial cell proliferation GO:0050673 1 0.014
cellular component assembly involved in morphogenesis GO:0010927 183 0.013
cellular response to stress GO:0033554 162 0.013
nematode male tail tip morphogenesis GO:0045138 77 0.013
Worm
regulation of signal transduction GO:0009966 135 0.013
meiotic nuclear division GO:0007126 300 0.013
microtubule based process GO:0007017 182 0.013
response to external biotic stimulus GO:0043207 101 0.013
regulation of molecular function GO:0065009 89 0.013
chromosome segregation GO:0007059 180 0.013
small gtpase mediated signal transduction GO:0007264 32 0.013
negative regulation of post embryonic development GO:0048581 208 0.013
Worm
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.013
ras protein signal transduction GO:0007265 31 0.013
rna metabolic process GO:0016070 228 0.013
myofibril assembly GO:0030239 154 0.013
female gamete generation GO:0007292 254 0.013
cellular nitrogen compound catabolic process GO:0044270 119 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.013
positive regulation of phosphate metabolic process GO:0045937 56 0.013
cellular protein localization GO:0034613 75 0.013
striated muscle cell development GO:0055002 157 0.013
tissue development GO:0009888 112 0.013
positive regulation of cell cycle GO:0045787 55 0.013
Worm
organic cyclic compound catabolic process GO:1901361 119 0.013
myosin filament organization GO:0031033 138 0.013
aromatic compound catabolic process GO:0019439 116 0.012
regulation of nematode larval development GO:0061062 260 0.012
Worm
purine nucleoside metabolic process GO:0042278 92 0.012
regulation of cell cycle process GO:0010564 145 0.012
regulation of behavior GO:0050795 97 0.012
Worm
adult behavior GO:0030534 3 0.012
transcription dna templated GO:0006351 168 0.012
purine containing compound metabolic process GO:0072521 95 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.012
myosin filament assembly GO:0031034 138 0.012
positive regulation of macromolecule metabolic process GO:0010604 149 0.012
cuticle development GO:0042335 100 0.012
gene silencing GO:0016458 143 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
Worm
carbohydrate derivative catabolic process GO:1901136 82 0.012
regulation of catabolic process GO:0009894 57 0.012
Worm
response to fungus GO:0009620 20 0.012
Worm
positive regulation of cell communication GO:0010647 69 0.012
cell part morphogenesis GO:0032990 152 0.012
meiotic chromosome segregation GO:0045132 139 0.012
positive regulation of molecular function GO:0044093 61 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
fertilization GO:0009566 63 0.012
regulation of cell division GO:0051302 142 0.012
striated muscle cell differentiation GO:0051146 158 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.012
regulation of response to stimulus GO:0048583 243 0.012
Worm
oogenesis GO:0048477 229 0.012
positive regulation of phosphorus metabolic process GO:0010562 56 0.012
regulation of mitotic cell cycle GO:0007346 76 0.012
Worm
protein modification process GO:0036211 207 0.012
muscle cell development GO:0055001 158 0.012
rna localization GO:0006403 3 0.012
nucleobase containing compound catabolic process GO:0034655 114 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
positive regulation of rna metabolic process GO:0051254 103 0.012
positive regulation of neurogenesis GO:0050769 4 0.011
neuromuscular junction development GO:0007528 2 0.011
positive regulation of signaling GO:0023056 66 0.011
anatomical structure formation involved in morphogenesis GO:0048646 250 0.011
lipid metabolic process GO:0006629 77 0.011
ribonucleotide metabolic process GO:0009259 99 0.011
membrane invagination GO:0010324 98 0.011
regulation of cell proliferation GO:0042127 105 0.011
regulation of protein targeting GO:1903533 3 0.011
macromolecule modification GO:0043412 218 0.011
phagocytosis GO:0006909 115 0.011
positive regulation of transcription dna templated GO:0045893 102 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
macromolecule catabolic process GO:0009057 202 0.011
Worm
cell recognition GO:0008037 85 0.011
single organism biosynthetic process GO:0044711 91 0.011
actomyosin structure organization GO:0031032 154 0.011
positive regulation of intracellular transport GO:0032388 2 0.011
regulation of phosphorus metabolic process GO:0051174 81 0.011
cell cell signaling GO:0007267 118 0.011
ribonucleoprotein complex assembly GO:0022618 4 0.011
pharyngeal pumping GO:0043050 58 0.011
Worm
regulation of macromolecule biosynthetic process GO:0010556 189 0.011
carbohydrate metabolic process GO:0005975 34 0.011
ribonucleoside triphosphate metabolic process GO:0009199 87 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.011
phagocytosis engulfment GO:0006911 98 0.011
aromatic compound biosynthetic process GO:0019438 192 0.011
regulation of response to wounding GO:1903034 1 0.011
regulation of localization GO:0032879 194 0.010
cell substrate adhesion GO:0031589 1 0.010
cell proliferation GO:0008283 116 0.010
axonal fasciculation GO:0007413 79 0.010
cellular response to organic substance GO:0071310 119 0.010
inductive cell migration GO:0040039 145 0.010
positive regulation of protein transport GO:0051222 4 0.010
regulation of biosynthetic process GO:0009889 189 0.010
regulation of rna metabolic process GO:0051252 173 0.010
regulation of locomotion GO:0040012 161 0.010
defense response to bacterium GO:0042742 86 0.010
regeneration GO:0031099 4 0.010
ribonucleoside monophosphate metabolic process GO:0009161 45 0.010
purine ribonucleoside catabolic process GO:0046130 75 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.010
cellular nitrogen compound biosynthetic process GO:0044271 192 0.010
purine ribonucleotide catabolic process GO:0009154 75 0.010

daf-8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.013
musculoskeletal system disease DOID:17 0 0.013
nervous system disease DOID:863 0 0.010