Caenorhabditis elegans

34 known processes

hel-1 (CELE_C26D10.2)

Protein HEL-1

hel-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multicellular organism reproduction GO:0032504 819 0.856
sexual reproduction GO:0019953 546 0.813
embryo development ending in birth or egg hatching GO:0009792 2992 0.762
developmental process involved in reproduction GO:0003006 1165 0.713
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.701
organ development GO:0048513 1102 0.687
post embryonic development GO:0009791 2152 0.656
embryo development GO:0009790 3052 0.651
vesicle mediated transport GO:0016192 852 0.634
multicellular organismal reproductive process GO:0048609 815 0.581
catabolic process GO:0009056 318 0.555
Human
single organism organelle organization GO:1902589 501 0.525
Fly
hermaphrodite genitalia development GO:0040035 734 0.484
protein metabolic process GO:0019538 422 0.484
gamete generation GO:0007276 461 0.468
organic substance catabolic process GO:1901575 294 0.444
Human
vulval development GO:0040025 333 0.441
establishment of localization GO:0051234 1171 0.439
Human Fly
positive regulation of cellular process GO:0048522 332 0.433
Human
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.390
Human
germ cell development GO:0007281 351 0.385
single organism reproductive process GO:0044702 1196 0.383
gonad development GO:0008406 840 0.365
regulation of nematode larval development GO:0061062 260 0.353
nucleobase containing compound metabolic process GO:0006139 406 0.339
Human Fly
organelle organization GO:0006996 783 0.332
Fly
multi organism reproductive process GO:0044703 867 0.329
female gamete generation GO:0007292 254 0.326
regulation of developmental process GO:0050793 684 0.304
reproductive system development GO:0061458 850 0.291
regulation of multicellular organismal process GO:0051239 726 0.275
organic cyclic compound catabolic process GO:1901361 119 0.270
Human
signal transduction GO:0007165 317 0.251
regulation of vulval development GO:0040028 248 0.243
cell migration GO:0016477 306 0.227
negative regulation of vulval development GO:0040027 206 0.219
meiotic cell cycle GO:0051321 335 0.218
cellular protein metabolic process GO:0044267 279 0.216
phosphate containing compound metabolic process GO:0006796 232 0.212
Human
regulation of post embryonic development GO:0048580 260 0.208
cell motility GO:0048870 313 0.205
glycosyl compound metabolic process GO:1901657 100 0.201
Human
carbohydrate derivative metabolic process GO:1901135 141 0.200
Human
oviposition GO:0018991 364 0.199
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.191
Human
post embryonic organ development GO:0048569 336 0.188
cellular component assembly GO:0022607 293 0.188
Human
tissue development GO:0009888 112 0.185
regulation of multicellular organismal development GO:2000026 317 0.180
mitotic cell cycle process GO:1903047 194 0.171
Fly
nucleic acid metabolic process GO:0090304 299 0.162
Human Fly
organonitrogen compound metabolic process GO:1901564 151 0.160
Human
regulation of gene expression GO:0010468 366 0.152
Human Fly
regulation of metabolic process GO:0019222 478 0.151
Human Fly
oogenesis GO:0048477 229 0.148
sex differentiation GO:0007548 909 0.146
negative regulation of nematode larval development GO:0061064 208 0.145
multicellular organismal reproductive behavior GO:0033057 384 0.144
locomotion GO:0040011 1634 0.143
head development GO:0060322 1 0.143
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.142
Human
multicellular organismal aging GO:0010259 812 0.141
intracellular receptor signaling pathway GO:0030522 2 0.139
positive regulation of developmental process GO:0051094 408 0.138
rna metabolic process GO:0016070 228 0.134
Human Fly
reproductive structure development GO:0048608 850 0.133
phosphorus metabolic process GO:0006793 232 0.130
Human
positive regulation of transcription dna templated GO:0045893 102 0.129
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.129
Human
positive regulation of rna biosynthetic process GO:1902680 102 0.121
Human
meiotic nuclear division GO:0007126 300 0.120
molting cycle GO:0042303 281 0.117
cellular macromolecular complex assembly GO:0034622 184 0.117
Human
endocytosis GO:0006897 819 0.116
rna localization GO:0006403 3 0.116
Human Fly
positive regulation of phosphorus metabolic process GO:0010562 56 0.111
gene expression GO:0010467 412 0.110
Human Fly
localization of cell GO:0051674 313 0.109
determination of adult lifespan GO:0008340 812 0.106
regulation of organelle organization GO:0033043 164 0.105
positive regulation of metabolic process GO:0009893 187 0.104
Human
multi multicellular organism process GO:0044706 390 0.103
purine ribonucleotide metabolic process GO:0009150 95 0.102
Human
protein complex subunit organization GO:0071822 280 0.100
Fly
macromolecule localization GO:0033036 771 0.100
Human Fly
posttranscriptional regulation of gene expression GO:0010608 166 0.099
aging GO:0007568 812 0.098
regulation of cellular biosynthetic process GO:0031326 189 0.097
Human
macromolecule catabolic process GO:0009057 202 0.096
negative regulation of developmental process GO:0051093 227 0.091
protein catabolic process GO:0030163 162 0.090
nucleobase containing compound catabolic process GO:0034655 114 0.088
Human
cell death GO:0008219 547 0.088
positive regulation of gene expression GO:0010628 112 0.086
Human
cell cycle process GO:0022402 482 0.085
Human Fly
cell cycle GO:0007049 526 0.084
Human Fly
purine nucleoside metabolic process GO:0042278 92 0.082
Human
positive regulation of growth GO:0045927 369 0.081
nervous system development GO:0007399 253 0.080
spermatogenesis GO:0007283 41 0.080
multi organism behavior GO:0051705 389 0.078
regulation of biological quality GO:0065008 741 0.078
regulation of cellular metabolic process GO:0031323 305 0.077
Human Fly
negative regulation of post embryonic development GO:0048581 208 0.077
positive regulation of nucleic acid templated transcription GO:1903508 102 0.074
Human
regulation of cellular component biogenesis GO:0044087 26 0.073
male gamete generation GO:0048232 41 0.073
small molecule metabolic process GO:0044281 186 0.073
Human
response to chemical GO:0042221 356 0.072
regulation of primary metabolic process GO:0080090 292 0.072
Human Fly
body morphogenesis GO:0010171 620 0.072
cell development GO:0048468 696 0.071
macromolecule modification GO:0043412 218 0.071
pronuclear migration GO:0035046 51 0.071
positive regulation of phosphate metabolic process GO:0045937 56 0.070
establishment of organelle localization GO:0051656 123 0.070
development of primary sexual characteristics GO:0045137 840 0.069
positive regulation of rna metabolic process GO:0051254 103 0.068
Human
cellular component biogenesis GO:0044085 297 0.068
Human
neurogenesis GO:0022008 236 0.067
mitotic nuclear division GO:0007067 89 0.067
negative regulation of biological process GO:0048519 567 0.066
Human
purine nucleotide metabolic process GO:0006163 95 0.065
Human
cellular component movement GO:0006928 388 0.064
single organism signaling GO:0044700 401 0.064
multi organism reproductive behavior GO:0044705 387 0.064
transport GO:0006810 1093 0.064
Human Fly
epithelium development GO:0060429 68 0.063
nucleobase containing small molecule metabolic process GO:0055086 115 0.063
Human
single organism transport GO:0044765 447 0.062
organelle fission GO:0048285 363 0.062
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.061
programmed cell death GO:0012501 500 0.060
regulation of growth GO:0040008 409 0.060
regulation of cellular component organization GO:0051128 248 0.060
growth GO:0040007 562 0.059
cellular biosynthetic process GO:0044249 315 0.058
Human
positive regulation of cellular biosynthetic process GO:0031328 109 0.058
Human
regulation of catabolic process GO:0009894 57 0.056
regulation of macromolecule metabolic process GO:0060255 421 0.055
Human Fly
regulation of phosphate metabolic process GO:0019220 81 0.054
negative regulation of multicellular organismal process GO:0051241 236 0.053
cellular localization GO:0051641 360 0.053
Human Fly
regulation of rna metabolic process GO:0051252 173 0.052
Human Fly
purine ribonucleoside metabolic process GO:0046128 92 0.051
Human
aromatic compound catabolic process GO:0019439 116 0.051
Human
single organism localization GO:1902578 518 0.051
membrane organization GO:0061024 135 0.051
positive regulation of developmental growth GO:0048639 354 0.051
maintenance of location GO:0051235 580 0.051
behavior GO:0007610 527 0.051
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.050
positive regulation of multicellular organismal process GO:0051240 417 0.050
ribonucleoside triphosphate metabolic process GO:0009199 87 0.050
Human
genitalia development GO:0048806 741 0.049
fertilization GO:0009566 63 0.049
microtubule based process GO:0007017 182 0.048
Fly
lipid storage GO:0019915 565 0.048
carboxylic acid biosynthetic process GO:0046394 21 0.048
cellular nitrogen compound catabolic process GO:0044270 119 0.047
Human
epithelial cell proliferation GO:0050673 1 0.047
ribonucleoprotein complex assembly GO:0022618 4 0.047
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.047
Human
positive regulation of vulval development GO:0040026 52 0.046
chromosome segregation GO:0007059 180 0.046
gene silencing GO:0016458 143 0.046
regulation of meiotic cell cycle GO:0051445 136 0.045
posttranscriptional gene silencing by rna GO:0035194 143 0.045
regulation of signal transduction GO:0009966 135 0.045
macromolecular complex assembly GO:0065003 193 0.045
Human
protein refolding GO:0042026 1 0.044
posttranscriptional gene silencing GO:0016441 143 0.044
ribonucleoside metabolic process GO:0009119 98 0.044
Human
nucleotide metabolic process GO:0009117 108 0.044
Human
nucleoside metabolic process GO:0009116 99 0.043
Human
carbohydrate derivative catabolic process GO:1901136 82 0.043
Human
carboxylic acid metabolic process GO:0019752 34 0.042
cellular response to chemical stimulus GO:0070887 129 0.042
developmental growth GO:0048589 412 0.041
regulation of jun kinase activity GO:0043506 3 0.041
establishment of nucleus localization GO:0040023 55 0.041
muscle organ morphogenesis GO:0048644 4 0.041
lipid localization GO:0010876 573 0.041
muscle tissue development GO:0060537 1 0.040
purine nucleoside triphosphate metabolic process GO:0009144 87 0.040
Human
organophosphate metabolic process GO:0019637 125 0.040
Human
oocyte construction GO:0007308 2 0.039
cell cell signaling GO:0007267 118 0.039
modification dependent protein catabolic process GO:0019941 32 0.039
regulation of multicellular organism growth GO:0040014 373 0.039
reproductive behavior GO:0019098 387 0.038
regulation of epithelial cell proliferation GO:0050678 1 0.038
negative regulation of gene expression GO:0010629 217 0.038
regulation of macromolecule biosynthetic process GO:0010556 189 0.038
Human
macromolecular complex subunit organization GO:0043933 320 0.037
Human Fly
death GO:0016265 547 0.037
regulation of localization GO:0032879 194 0.037
positive regulation of nematode larval development GO:0061063 54 0.036
oxoacid metabolic process GO:0043436 47 0.036
organic acid metabolic process GO:0006082 47 0.035
regulation of developmental growth GO:0048638 389 0.035
protein complex biogenesis GO:0070271 186 0.035
apoptotic process GO:0006915 478 0.034
biosynthetic process GO:0009058 323 0.034
Human
protein modification process GO:0036211 207 0.034
regulation of cell division GO:0051302 142 0.034
single organism catabolic process GO:0044712 129 0.034
Human
regulation of intracellular signal transduction GO:1902531 77 0.034
regulation of cell differentiation GO:0045595 81 0.034
cellular response to organic substance GO:0071310 119 0.033
neuron differentiation GO:0030182 217 0.033
receptor mediated endocytosis GO:0006898 715 0.033
heterocycle catabolic process GO:0046700 119 0.033
Human
response to organic substance GO:0010033 131 0.032
single fertilization GO:0007338 61 0.031
organelle localization GO:0051640 127 0.031
mrna processing GO:0006397 13 0.031
Human Fly
signaling GO:0023052 401 0.031
rna processing GO:0006396 34 0.031
Human Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.031
Human Fly
rna interference GO:0016246 137 0.031
regulation of catalytic activity GO:0050790 78 0.030
negative regulation of cellular process GO:0048523 239 0.030
Human
dauer larval development GO:0040024 92 0.030
positive regulation of multicellular organism growth GO:0040018 352 0.030
rna biosynthetic process GO:0032774 169 0.030
Human
organic substance transport GO:0071702 113 0.030
Human Fly
nucleoside phosphate metabolic process GO:0006753 108 0.030
Human
establishment of localization in cell GO:0051649 318 0.029
Human Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.029
cellular catabolic process GO:0044248 199 0.029
Human
regulation of rna splicing GO:0043484 7 0.029
Fly
ubiquitin dependent protein catabolic process GO:0006511 32 0.028
oocyte axis specification GO:0007309 2 0.028
cellular protein modification process GO:0006464 207 0.028
positive regulation of catalytic activity GO:0043085 59 0.027
cell proliferation GO:0008283 116 0.027
cellular component morphogenesis GO:0032989 318 0.027
regulation of response to stimulus GO:0048583 243 0.026
Human
nucleoside triphosphate metabolic process GO:0009141 87 0.026
Human
ribose phosphate metabolic process GO:0019693 99 0.026
Human
organic cyclic compound biosynthetic process GO:1901362 195 0.025
Human
negative regulation of metabolic process GO:0009892 240 0.025
generation of neurons GO:0048699 235 0.025
response to endogenous stimulus GO:0009719 33 0.025
protein phosphorylation GO:0006468 85 0.025
regulation of cell death GO:0010941 65 0.025
nuclear migration GO:0007097 54 0.025
regulation of cell cycle process GO:0010564 145 0.025
Human
ribonucleotide metabolic process GO:0009259 99 0.024
Human
neuron projection morphogenesis GO:0048812 114 0.024
positive regulation of macromolecule metabolic process GO:0010604 149 0.024
Human
regulation of cell cycle GO:0051726 194 0.024
Human
macromolecule biosynthetic process GO:0009059 250 0.024
Human
response to wounding GO:0009611 4 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.023
modification dependent macromolecule catabolic process GO:0043632 32 0.023
nucleoside catabolic process GO:0009164 78 0.023
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.022
regulation of nucleic acid templated transcription GO:1903506 165 0.022
Human
purine containing compound catabolic process GO:0072523 75 0.022
Human
signal transduction by phosphorylation GO:0023014 31 0.022
regulation of neuron differentiation GO:0045664 40 0.022
nucleic acid templated transcription GO:0097659 169 0.022
Human
regulation of cell proliferation GO:0042127 105 0.022
transcription from rna polymerase ii promoter GO:0006366 149 0.022
cell morphogenesis GO:0000902 163 0.022
nucleoside phosphate catabolic process GO:1901292 77 0.021
Human
mapk cascade GO:0000165 31 0.021
gene silencing by rna GO:0031047 143 0.021
positive regulation of catabolic process GO:0009896 38 0.021
multicellular organism growth GO:0035264 385 0.021
secretion GO:0046903 147 0.021
cell type specific apoptotic process GO:0097285 4 0.020
protein localization GO:0008104 205 0.020
positive regulation of cellular metabolic process GO:0031325 178 0.020
Human
regulation of meiosis GO:0040020 94 0.020
negative regulation of cellular component organization GO:0051129 33 0.020
mitotic spindle organization GO:0007052 81 0.020
Fly
regulation of mrna splicing via spliceosome GO:0048024 7 0.020
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.020
cellular response to abiotic stimulus GO:0071214 4 0.020
regulation of phosphorus metabolic process GO:0051174 81 0.020
regulation of nitrogen compound metabolic process GO:0051171 222 0.020
Human Fly
rna splicing GO:0008380 8 0.019
Human Fly
regulation of apoptotic signaling pathway GO:2001233 1 0.019
intracellular signal transduction GO:0035556 96 0.019
positive regulation of cell communication GO:0010647 69 0.019
dna templated transcription elongation GO:0006354 1 0.019
Human
regulation of anatomical structure morphogenesis GO:0022603 51 0.019
positive regulation of molecular function GO:0044093 61 0.018
response to external stimulus GO:0009605 289 0.018
protein folding GO:0006457 7 0.018
regulation of gene expression epigenetic GO:0040029 163 0.018
epidermis development GO:0008544 24 0.018
organic acid biosynthetic process GO:0016053 21 0.018
regulation of protein kinase activity GO:0045859 28 0.018
neuron development GO:0048666 199 0.017
purine ribonucleoside catabolic process GO:0046130 75 0.017
Human
mrna splicing via spliceosome GO:0000398 8 0.017
Human Fly
cell division GO:0051301 262 0.017
regulation of rna biosynthetic process GO:2001141 165 0.017
Human
phosphorylation GO:0016310 116 0.017
regulation of phosphorylation GO:0042325 45 0.017
regulation of protein localization GO:0032880 50 0.017
rna splicing via transesterification reactions GO:0000375 8 0.017
Human Fly
regulation of nervous system development GO:0051960 41 0.016
cuticle development GO:0042335 100 0.016
nucleobase containing compound biosynthetic process GO:0034654 184 0.016
Human
male sex differentiation GO:0046661 86 0.016
small gtpase mediated signal transduction GO:0007264 32 0.016
purine nucleoside triphosphate catabolic process GO:0009146 72 0.016
Human
regulation of purine nucleotide metabolic process GO:1900542 37 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
establishment of mitotic spindle orientation GO:0000132 28 0.016
response to abiotic stimulus GO:0009628 152 0.016
regulation of protein stability GO:0031647 3 0.016
embryonic morphogenesis GO:0048598 152 0.016
cellular nitrogen compound biosynthetic process GO:0044271 192 0.015
Human
mrna metabolic process GO:0016071 31 0.015
Human Fly
purine containing compound metabolic process GO:0072521 95 0.015
Human
collagen and cuticulin based cuticle development GO:0040002 99 0.015
regulation of molecular function GO:0065009 89 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.014
single organism biosynthetic process GO:0044711 91 0.014
organophosphate catabolic process GO:0046434 81 0.014
Human
negative regulation of rna metabolic process GO:0051253 53 0.014
regulation of mitotic cell cycle GO:0007346 76 0.014
regulation of cell communication GO:0010646 176 0.014
nucleotide catabolic process GO:0009166 77 0.014
Human
negative regulation of neurogenesis GO:0050768 4 0.014
regeneration GO:0031099 4 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
regulation of protein metabolic process GO:0051246 81 0.013
maintenance of protein location in cell GO:0032507 12 0.013
positive regulation of intracellular signal transduction GO:1902533 24 0.013
regulation of neurogenesis GO:0050767 40 0.013
histone modification GO:0016570 30 0.013
ribonucleotide catabolic process GO:0009261 75 0.013
Human
muscle structure development GO:0061061 191 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
dna templated transcription termination GO:0006353 1 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
regulation of nucleotide catabolic process GO:0030811 35 0.013
ras protein signal transduction GO:0007265 31 0.013
intracellular transport GO:0046907 77 0.013
Human Fly
secretion by cell GO:0032940 138 0.013
regulation of chromatin modification GO:1903308 2 0.012
tube development GO:0035295 126 0.012
regulation of nucleoside metabolic process GO:0009118 37 0.012
regulation of mrna processing GO:0050684 7 0.012
Fly
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.012
cellular ketone metabolic process GO:0042180 14 0.012
cell projection organization GO:0030030 231 0.012
cellular protein catabolic process GO:0044257 37 0.012
proteolysis GO:0006508 61 0.012
positive regulation of post embryonic development GO:0048582 54 0.012
neuron apoptotic process GO:0051402 4 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.012
positive regulation of cellular catabolic process GO:0031331 35 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
regulation of synapse assembly GO:0051963 2 0.011
negative regulation of cellular catabolic process GO:0031330 9 0.011
chromatin assembly GO:0031497 1 0.011
regulation of chromosome organization GO:0033044 20 0.011
ribonucleoside triphosphate catabolic process GO:0009203 72 0.011
Human
regulation of epithelial cell differentiation GO:0030856 4 0.011
cytoskeleton dependent cytokinesis GO:0061640 35 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.011
Human
cellular macromolecule catabolic process GO:0044265 73 0.011
ribonucleoside monophosphate metabolic process GO:0009161 45 0.011
Human
regulation of purine nucleotide catabolic process GO:0033121 35 0.011
rna transport GO:0050658 3 0.011
Human Fly
protein oligomerization GO:0051259 4 0.011
carbohydrate derivative biosynthetic process GO:1901137 46 0.010
nucleoside monophosphate metabolic process GO:0009123 46 0.010
Human
cellular response to endogenous stimulus GO:0071495 32 0.010
nucleoside triphosphate catabolic process GO:0009143 72 0.010
Human
organelle assembly GO:0070925 214 0.010
response to nitrogen compound GO:1901698 25 0.010
positive regulation of phosphorylation GO:0042327 27 0.010
cellular amine metabolic process GO:0044106 15 0.010
purine nucleoside catabolic process GO:0006152 75 0.010
Human

hel-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.012