Caenorhabditis elegans

26 known processes

his-1 (CELE_T10C6.14)

Protein HIS-1

his-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cell cycle process GO:1903046 170 0.990
Yeast
digestive tract development GO:0048565 122 0.990
Worm
hermaphrodite genitalia development GO:0040035 734 0.982
digestive system development GO:0055123 122 0.979
Worm
negative regulation of gene expression epigenetic GO:0045814 2 0.977
Yeast
meiotic cell cycle GO:0051321 335 0.970
Yeast
embryo development ending in birth or egg hatching GO:0009792 2992 0.967
reproductive system development GO:0061458 850 0.958
embryo development GO:0009790 3052 0.948
gonad development GO:0008406 840 0.945
genitalia development GO:0048806 741 0.941
sex differentiation GO:0007548 909 0.932
pharynx development GO:0060465 51 0.928
Worm
defense response GO:0006952 296 0.922
Worm
developmental process involved in reproduction GO:0003006 1165 0.915
post embryonic development GO:0009791 2152 0.913
reproductive structure development GO:0048608 850 0.909
development of primary sexual characteristics GO:0045137 840 0.904
sexual reproduction GO:0019953 546 0.891
Yeast
locomotion GO:0040011 1634 0.869
Worm
tube development GO:0035295 126 0.861
Worm
single organism reproductive process GO:0044702 1196 0.859
multicellular organism reproduction GO:0032504 819 0.843
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.836
Worm
transcription dna templated GO:0006351 168 0.831
Yeast Worm
regulation of transcription dna templated GO:0006355 164 0.816
Yeast Worm
regulation of rna biosynthetic process GO:2001141 165 0.814
Yeast Worm
positive regulation of rna biosynthetic process GO:1902680 102 0.807
Worm
nucleic acid templated transcription GO:0097659 169 0.798
Yeast Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.794
Yeast Worm
organ development GO:0048513 1102 0.788
cellular macromolecule biosynthetic process GO:0034645 247 0.775
Yeast Worm
multicellular organismal reproductive behavior GO:0033057 384 0.770
positive regulation of nucleic acid templated transcription GO:1903508 102 0.758
Worm
organelle organization GO:0006996 783 0.757
Yeast Worm
cellular nitrogen compound biosynthetic process GO:0044271 192 0.740
Yeast Worm
organic cyclic compound biosynthetic process GO:1901362 195 0.739
Yeast Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.725
Yeast Worm
negative regulation of rna biosynthetic process GO:1902679 53 0.721
Yeast
rna biosynthetic process GO:0032774 169 0.718
Yeast Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.716
Yeast Worm
multicellular organismal reproductive process GO:0048609 815 0.707
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.706
Yeast Worm
regulation of primary metabolic process GO:0080090 292 0.700
Yeast Worm
negative regulation of transcription dna templated GO:0045892 53 0.699
Yeast
oviposition GO:0018991 364 0.688
regulation of gene expression epigenetic GO:0040029 163 0.685
Yeast
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.645
Worm
cellular biosynthetic process GO:0044249 315 0.639
Yeast Worm
negative regulation of biosynthetic process GO:0009890 65 0.639
Yeast
regulation of nucleic acid templated transcription GO:1903506 165 0.639
Yeast Worm
dna repair GO:0006281 23 0.635
multi organism reproductive process GO:0044703 867 0.630
Yeast
regulation of rna metabolic process GO:0051252 173 0.617
Yeast Worm
single organism localization GO:1902578 518 0.606
Worm
chromatin modification GO:0016568 32 0.606
Yeast
heterocycle biosynthetic process GO:0018130 187 0.604
Yeast Worm
positive regulation of gene expression GO:0010628 112 0.598
Worm
negative regulation of nucleic acid templated transcription GO:1903507 53 0.586
Yeast
endocytosis GO:0006897 819 0.577
Worm
gene silencing GO:0016458 143 0.575
Yeast
negative regulation of biological process GO:0048519 567 0.575
Yeast
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.562
Worm
gene expression GO:0010467 412 0.561
Yeast Worm
nucleobase containing compound biosynthetic process GO:0034654 184 0.542
Yeast Worm
aromatic compound biosynthetic process GO:0019438 192 0.540
Yeast Worm
rna metabolic process GO:0016070 228 0.535
Yeast Worm
regulation of macromolecule metabolic process GO:0060255 421 0.533
Yeast Worm
histone modification GO:0016570 30 0.525
Yeast
regulation of macromolecule biosynthetic process GO:0010556 189 0.521
Yeast Worm
regulation of biosynthetic process GO:0009889 189 0.517
Yeast Worm
regulation of cellular biosynthetic process GO:0031326 189 0.515
Yeast Worm
nucleobase containing compound metabolic process GO:0006139 406 0.510
Yeast Worm
nucleic acid metabolic process GO:0090304 299 0.501
Yeast Worm
regulation of metabolic process GO:0019222 478 0.495
Yeast Worm
cell cycle process GO:0022402 482 0.494
Yeast
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.485
Worm
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.481
Yeast
chromosome organization GO:0051276 104 0.480
Yeast
biosynthetic process GO:0009058 323 0.479
Yeast Worm
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.475
Yeast
positive regulation of metabolic process GO:0009893 187 0.473
Worm
transcription from rna polymerase ii promoter GO:0006366 149 0.470
Yeast Worm
receptor mediated endocytosis GO:0006898 715 0.462
Worm
establishment of localization GO:0051234 1171 0.460
Worm
vesicle mediated transport GO:0016192 852 0.447
Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.439
Yeast
innate immune response GO:0045087 190 0.438
positive regulation of biosynthetic process GO:0009891 109 0.426
Worm
anatomical structure formation involved in morphogenesis GO:0048646 250 0.422
Yeast Worm
covalent chromatin modification GO:0016569 30 0.419
Yeast
apoptotic process GO:0006915 478 0.415
establishment of localization in cell GO:0051649 318 0.409
Worm
macromolecule biosynthetic process GO:0009059 250 0.403
Yeast Worm
cell cycle GO:0007049 526 0.401
Yeast
protein complex subunit organization GO:0071822 280 0.400
Worm
single organism organelle organization GO:1902589 501 0.392
Yeast Worm
positive regulation of macromolecule metabolic process GO:0010604 149 0.390
Worm
regulation of gene expression GO:0010468 366 0.390
Yeast Worm
single organism transport GO:0044765 447 0.387
Worm
organelle assembly GO:0070925 214 0.380
Worm
negative regulation of gene expression GO:0010629 217 0.366
Yeast
negative regulation of metabolic process GO:0009892 240 0.364
Yeast
positive regulation of cellular biosynthetic process GO:0031328 109 0.360
Worm
negative regulation of rna metabolic process GO:0051253 53 0.357
Yeast
muscle structure development GO:0061061 191 0.355
Worm
cellular response to dna damage stimulus GO:0006974 41 0.350
macromolecular complex subunit organization GO:0043933 320 0.347
Yeast Worm
striated muscle cell differentiation GO:0051146 158 0.337
Worm
muscle cell differentiation GO:0042692 171 0.331
Worm
negative regulation of cellular process GO:0048523 239 0.329
Yeast
cellular component morphogenesis GO:0032989 318 0.322
Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.317
Yeast
secretion by cell GO:0032940 138 0.315
Worm
regulation of cellular metabolic process GO:0031323 305 0.313
Yeast Worm
chromatin organization GO:0006325 32 0.311
Yeast
negative regulation of cellular biosynthetic process GO:0031327 65 0.311
Yeast
cellular localization GO:0051641 360 0.309
Worm
body morphogenesis GO:0010171 620 0.308
Worm
cytoskeleton organization GO:0007010 339 0.307
Worm
negative regulation of macromolecule metabolic process GO:0010605 229 0.306
Yeast
transport GO:0006810 1093 0.304
Worm
negative regulation of cellular metabolic process GO:0031324 95 0.283
Yeast
organic substance biosynthetic process GO:1901576 323 0.281
Yeast Worm
cell development GO:0048468 696 0.278
Worm
multi multicellular organism process GO:0044706 390 0.256
secretion GO:0046903 147 0.245
Worm
cellular component biogenesis GO:0044085 297 0.243
Worm
macromolecule modification GO:0043412 218 0.233
Yeast
multi organism behavior GO:0051705 389 0.232
reproductive behavior GO:0019098 387 0.228
striated muscle cell development GO:0055002 157 0.226
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.225
Yeast
positive regulation of rna metabolic process GO:0051254 103 0.223
Worm
multi organism reproductive behavior GO:0044705 387 0.222
cellular protein metabolic process GO:0044267 279 0.220
Yeast
protein modification process GO:0036211 207 0.219
Yeast
positive regulation of cellular metabolic process GO:0031325 178 0.215
Worm
cellular protein modification process GO:0006464 207 0.202
Yeast
cellular protein complex assembly GO:0043623 178 0.197
Worm
protein complex biogenesis GO:0070271 186 0.197
Worm
death GO:0016265 547 0.196
muscle cell development GO:0055001 158 0.191
Worm
actin cytoskeleton organization GO:0030036 184 0.189
Worm
myofibril assembly GO:0030239 154 0.183
Worm
protein complex assembly GO:0006461 186 0.179
Worm
meiotic nuclear division GO:0007126 300 0.179
actin filament based process GO:0030029 191 0.172
Worm
cell death GO:0008219 547 0.171
macromolecule localization GO:0033036 771 0.169
Worm
cellular component assembly involved in morphogenesis GO:0010927 183 0.168
Worm
macromolecular complex assembly GO:0065003 193 0.163
Worm
programmed cell death GO:0012501 500 0.153
regulation of biological quality GO:0065008 741 0.148
Worm
organelle fission GO:0048285 363 0.144
protein metabolic process GO:0019538 422 0.144
Yeast
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.143
actomyosin structure organization GO:0031032 154 0.140
Worm
positive regulation of transcription dna templated GO:0045893 102 0.139
Worm
cellular component assembly GO:0022607 293 0.135
Worm
cellular macromolecular complex assembly GO:0034622 184 0.132
Worm
gamete generation GO:0007276 461 0.128
fertilization GO:0009566 63 0.128
striated muscle myosin thick filament assembly GO:0071688 138 0.115
Worm
vulval development GO:0040025 333 0.111
cellular response to stress GO:0033554 162 0.111
lipid localization GO:0010876 573 0.109
Worm
regulation of vulval development GO:0040028 248 0.108
germ cell development GO:0007281 351 0.105
nucleus organization GO:0006997 38 0.105
positive regulation of cellular process GO:0048522 332 0.101
Worm
behavior GO:0007610 527 0.097
pronuclear migration GO:0035046 51 0.089
meiotic chromosome segregation GO:0045132 139 0.088
lipid storage GO:0019915 565 0.088
Worm
maintenance of location GO:0051235 580 0.084
Worm
negative regulation of nematode larval development GO:0061064 208 0.082
myosin filament assembly GO:0031034 138 0.075
Worm
myosin filament organization GO:0031033 138 0.074
Worm
determination of adult lifespan GO:0008340 812 0.063
dna metabolic process GO:0006259 74 0.063
female gamete generation GO:0007292 254 0.062
multicellular organismal aging GO:0010259 812 0.056
regulation of nematode larval development GO:0061062 260 0.054
oogenesis GO:0048477 229 0.053
aging GO:0007568 812 0.050
negative regulation of vulval development GO:0040027 206 0.041
regulation of meiotic cell cycle GO:0051445 136 0.041
regulation of post embryonic development GO:0048580 260 0.039
negative regulation of multicellular organismal process GO:0051241 236 0.038
regulation of cell cycle GO:0051726 194 0.038
cell projection organization GO:0030030 231 0.036
cell division GO:0051301 262 0.035
inductive cell migration GO:0040039 145 0.035
regulation of multicellular organismal process GO:0051239 726 0.035
mitotic cell cycle process GO:1903047 194 0.034
cell motility GO:0048870 313 0.034
multicellular organism growth GO:0035264 385 0.033
chromatin assembly or disassembly GO:0006333 1 0.032
regulation of cell division GO:0051302 142 0.032
regulation of developmental growth GO:0048638 389 0.031
negative regulation of post embryonic development GO:0048581 208 0.031
ion transport GO:0006811 113 0.031
regulation of developmental process GO:0050793 684 0.030
single organism catabolic process GO:0044712 129 0.030
defense response to bacterium GO:0042742 86 0.027
regulation of cellular component organization GO:0051128 248 0.027
regulation of multicellular organismal development GO:2000026 317 0.027
response to external stimulus GO:0009605 289 0.026
regulation of organelle organization GO:0033043 164 0.026
single fertilization GO:0007338 61 0.024
signal transduction GO:0007165 317 0.024
response to wounding GO:0009611 4 0.024
catabolic process GO:0009056 318 0.024
regulation of nuclear division GO:0051783 115 0.024
post embryonic organ development GO:0048569 336 0.023
macromolecule catabolic process GO:0009057 202 0.023
negative regulation of developmental process GO:0051093 227 0.023
regulation of multicellular organism growth GO:0040014 373 0.023
regulation of cell cycle process GO:0010564 145 0.021
growth GO:0040007 562 0.021
phosphorus metabolic process GO:0006793 232 0.021
cell migration GO:0016477 306 0.021
oocyte axis specification GO:0007309 2 0.021
chromosome segregation GO:0007059 180 0.020
immune response GO:0006955 192 0.020
regulation of localization GO:0032879 194 0.020
organic substance catabolic process GO:1901575 294 0.020
signaling GO:0023052 401 0.019
organelle localization GO:0051640 127 0.018
positive regulation of multicellular organism growth GO:0040018 352 0.018
localization of cell GO:0051674 313 0.018
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.018
positive regulation of growth GO:0045927 369 0.018
single organism signaling GO:0044700 401 0.018
establishment of organelle localization GO:0051656 123 0.018
nucleoside metabolic process GO:0009116 99 0.017
positive regulation of developmental growth GO:0048639 354 0.017
organonitrogen compound metabolic process GO:1901564 151 0.017
regulation of epithelial cell proliferation GO:0050678 1 0.017
nucleobase containing small molecule metabolic process GO:0055086 115 0.017
ion transmembrane transport GO:0034220 91 0.016
developmental growth GO:0048589 412 0.016
regulation of transport GO:0051049 91 0.016
small molecule metabolic process GO:0044281 186 0.016
oocyte development GO:0048599 44 0.016
microtubule based process GO:0007017 182 0.016
cellular component movement GO:0006928 388 0.016
regulation of mitotic cell cycle GO:0007346 76 0.016
neuron projection guidance GO:0097485 82 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
protein oligomerization GO:0051259 4 0.015
molting cycle GO:0042303 281 0.015
regulation of growth GO:0040008 409 0.015
cellular catabolic process GO:0044248 199 0.015
protein localization GO:0008104 205 0.015
defense response to other organism GO:0098542 100 0.015
regulation of cytoplasmic transport GO:1903649 3 0.015
filopodium assembly GO:0046847 2 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.015
cell morphogenesis involved in differentiation GO:0000904 112 0.015
oocyte construction GO:0007308 2 0.014
organic substance transport GO:0071702 113 0.014
regulation of cell projection assembly GO:0060491 3 0.014
neurogenesis GO:0022008 236 0.014
axon guidance GO:0007411 82 0.014
chemotaxis GO:0006935 120 0.014
regulation of meiosis GO:0040020 94 0.013
organophosphate metabolic process GO:0019637 125 0.013
canonical wnt signaling pathway GO:0060070 3 0.013
single organism intracellular transport GO:1902582 70 0.013
nucleoside monophosphate metabolic process GO:0009123 46 0.012
golgi vesicle transport GO:0048193 3 0.012
cation transport GO:0006812 78 0.012
protein catabolic process GO:0030163 162 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
phosphate containing compound metabolic process GO:0006796 232 0.012
amine metabolic process GO:0009308 15 0.012
purine ribonucleotide metabolic process GO:0009150 95 0.012
nuclear migration GO:0007097 54 0.012
regulation of filopodium assembly GO:0051489 2 0.012
taxis GO:0042330 128 0.012
purine nucleoside metabolic process GO:0042278 92 0.012
regulation of protein stability GO:0031647 3 0.012
ribonucleotide metabolic process GO:0009259 99 0.012
oocyte differentiation GO:0009994 45 0.012
axon development GO:0061564 163 0.012
defense response to gram negative bacterium GO:0050829 64 0.012
positive regulation of nematode larval development GO:0061063 54 0.012
phosphorylation GO:0016310 116 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
endoplasmic reticulum unfolded protein response GO:0030968 66 0.011
negative regulation of cell cycle GO:0045786 53 0.011
posttranscriptional regulation of gene expression GO:0010608 166 0.011
regulation of protein targeting GO:1903533 3 0.011
nucleoside phosphate metabolic process GO:0006753 108 0.011
cytokinesis GO:0000910 80 0.011
positive regulation of vulval development GO:0040026 52 0.011
sensory organ morphogenesis GO:0090596 2 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
regulation of nucleocytoplasmic transport GO:0046822 3 0.011
neuron development GO:0048666 199 0.011
posttranscriptional gene silencing GO:0016441 143 0.011
phagocytosis GO:0006909 115 0.010
ribonucleoside metabolic process GO:0009119 98 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.010
rna interference GO:0016246 137 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
regulation of synapse assembly GO:0051963 2 0.010
cellular response to unfolded protein GO:0034620 71 0.010

his-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012