Caenorhabditis elegans

10 known processes

zwl-1 (CELE_Y39G10AR.2)

Protein ZWL-1

zwl-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic sister chromatid segregation GO:0000070 38 0.581
Fly
multicellular organism reproduction GO:0032504 819 0.544
embryo development GO:0009790 3052 0.497
organelle fission GO:0048285 363 0.468
Fly
meiotic nuclear division GO:0007126 300 0.417
sister chromatid segregation GO:0000819 46 0.368
Fly
germ cell development GO:0007281 351 0.361
gamete generation GO:0007276 461 0.342
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.328
oogenesis GO:0048477 229 0.310
cell cycle process GO:0022402 482 0.305
Human Fly
aging GO:0007568 812 0.303
meiotic cell cycle process GO:1903046 170 0.283
meiotic cell cycle GO:0051321 335 0.274
meiotic chromosome segregation GO:0045132 139 0.265
chromosome segregation GO:0007059 180 0.250
Fly
determination of adult lifespan GO:0008340 812 0.247
multicellular organismal reproductive process GO:0048609 815 0.244
multicellular organismal aging GO:0010259 812 0.220
growth GO:0040007 562 0.216
female gamete generation GO:0007292 254 0.212
apoptotic process GO:0006915 478 0.210
embryo development ending in birth or egg hatching GO:0009792 2992 0.206
sexual reproduction GO:0019953 546 0.205
negative regulation of macromolecule metabolic process GO:0010605 229 0.182
Fly
positive regulation of multicellular organismal process GO:0051240 417 0.181
post embryonic development GO:0009791 2152 0.181
developmental growth GO:0048589 412 0.161
sex differentiation GO:0007548 909 0.158
chromosome organization GO:0051276 104 0.151
Fly
cell death GO:0008219 547 0.145
genitalia development GO:0048806 741 0.143
development of primary sexual characteristics GO:0045137 840 0.142
cell cycle GO:0007049 526 0.141
Human Fly
mitotic cell cycle process GO:1903047 194 0.134
Human Fly
single organism organelle organization GO:1902589 501 0.134
Fly
single organism reproductive process GO:0044702 1196 0.129
organelle organization GO:0006996 783 0.128
Fly
programmed cell death GO:0012501 500 0.125
regulation of macromolecule metabolic process GO:0060255 421 0.121
Fly
cell division GO:0051301 262 0.121
Fly
death GO:0016265 547 0.119
reproductive structure development GO:0048608 850 0.119
positive regulation of cellular process GO:0048522 332 0.111
chromosome organization involved in meiosis GO:0070192 25 0.107
transport GO:0006810 1093 0.103
mitotic nuclear division GO:0007067 89 0.100
Fly
cellular localization GO:0051641 360 0.098
organic substance catabolic process GO:1901575 294 0.093
Fly
pronuclear migration GO:0035046 51 0.093
negative regulation of biological process GO:0048519 567 0.088
Human Fly
oviposition GO:0018991 364 0.087
regulation of multicellular organismal process GO:0051239 726 0.087
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.086
establishment of localization GO:0051234 1171 0.085
macromolecule localization GO:0033036 771 0.082
developmental process involved in reproduction GO:0003006 1165 0.080
regulation of developmental growth GO:0048638 389 0.079
multi organism reproductive process GO:0044703 867 0.077
reproductive system development GO:0061458 850 0.076
regulation of cell cycle process GO:0010564 145 0.075
Human Fly
negative regulation of metabolic process GO:0009892 240 0.074
Fly
positive regulation of developmental growth GO:0048639 354 0.074
response to chemical GO:0042221 356 0.074
regulation of developmental process GO:0050793 684 0.071
response to external stimulus GO:0009605 289 0.069
protein catabolic process GO:0030163 162 0.069
Fly
nucleoside catabolic process GO:0009164 78 0.069
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.069
regulation of growth GO:0040008 409 0.068
hermaphrodite genitalia development GO:0040035 734 0.068
regulation of biological quality GO:0065008 741 0.068
positive regulation of chromosome organization GO:2001252 2 0.065
lipid storage GO:0019915 565 0.064
positive regulation of developmental process GO:0051094 408 0.064
positive regulation of growth GO:0045927 369 0.063
macromolecular complex assembly GO:0065003 193 0.061
small molecule metabolic process GO:0044281 186 0.060
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.060
multicellular organism growth GO:0035264 385 0.055
regulation of chromosome segregation GO:0051983 20 0.054
Fly
maintenance of location GO:0051235 580 0.053
lipid localization GO:0010876 573 0.053
positive regulation of multicellular organism growth GO:0040018 352 0.052
multicellular organismal reproductive behavior GO:0033057 384 0.052
regulation of primary metabolic process GO:0080090 292 0.051
Fly
organelle localization GO:0051640 127 0.050
regulation of organelle organization GO:0033043 164 0.049
Fly
cytoskeleton organization GO:0007010 339 0.049
single organism catabolic process GO:0044712 129 0.048
Fly
negative regulation of gene expression GO:0010629 217 0.048
Fly
cellular catabolic process GO:0044248 199 0.047
Fly
vesicle mediated transport GO:0016192 852 0.047
single organism localization GO:1902578 518 0.047
regulation of multicellular organism growth GO:0040014 373 0.047
body morphogenesis GO:0010171 620 0.047
positive regulation of metabolic process GO:0009893 187 0.046
head development GO:0060322 1 0.046
cellular component biogenesis GO:0044085 297 0.046
posttranscriptional regulation of gene expression GO:0010608 166 0.045
mitotic sister chromatid separation GO:0051306 13 0.045
Fly
locomotion GO:0040011 1634 0.044
organ development GO:0048513 1102 0.044
gonad development GO:0008406 840 0.043
single fertilization GO:0007338 61 0.043
organonitrogen compound metabolic process GO:1901564 151 0.042
regulation of metabolic process GO:0019222 478 0.041
Fly
oocyte differentiation GO:0009994 45 0.041
posttranscriptional gene silencing GO:0016441 143 0.041
glycosyl compound metabolic process GO:1901657 100 0.041
posttranscriptional gene silencing by rna GO:0035194 143 0.040
cellular component assembly GO:0022607 293 0.040
protein metabolic process GO:0019538 422 0.039
Fly
regulation of catabolic process GO:0009894 57 0.039
Fly
membrane organization GO:0061024 135 0.039
purine nucleoside metabolic process GO:0042278 92 0.039
macromolecular complex subunit organization GO:0043933 320 0.038
regulation of gene expression GO:0010468 366 0.038
Fly
nucleobase containing compound metabolic process GO:0006139 406 0.038
positive regulation of catalytic activity GO:0043085 59 0.037
organelle assembly GO:0070925 214 0.037
regulation of cell division GO:0051302 142 0.037
Fly
gene silencing GO:0016458 143 0.036
polar body extrusion after meiotic divisions GO:0040038 14 0.036
nuclear migration GO:0007097 54 0.036
gene expression GO:0010467 412 0.036
Fly
multi organism reproductive behavior GO:0044705 387 0.036
macromolecule catabolic process GO:0009057 202 0.036
Fly
purine nucleotide metabolic process GO:0006163 95 0.035
cytokinesis GO:0000910 80 0.035
oocyte development GO:0048599 44 0.035
organonitrogen compound catabolic process GO:1901565 90 0.035
establishment of localization in cell GO:0051649 318 0.034
purine containing compound metabolic process GO:0072521 95 0.034
neuron projection extension involved in neuron projection guidance GO:1902284 13 0.033
purine containing compound catabolic process GO:0072523 75 0.033
purine nucleoside triphosphate metabolic process GO:0009144 87 0.033
female meiotic division GO:0007143 17 0.033
negative regulation of gene expression epigenetic GO:0045814 2 0.032
ribose phosphate metabolic process GO:0019693 99 0.032
nucleoside phosphate catabolic process GO:1901292 77 0.032
nervous system development GO:0007399 253 0.032
nucleotide catabolic process GO:0009166 77 0.032
ribonucleoside monophosphate metabolic process GO:0009161 45 0.032
organic cyclic compound catabolic process GO:1901361 119 0.032
cell development GO:0048468 696 0.031
ras protein signal transduction GO:0007265 31 0.031
actin cytoskeleton organization GO:0030036 184 0.031
regulation of gene expression epigenetic GO:0040029 163 0.031
dna repair GO:0006281 23 0.031
endocytosis GO:0006897 819 0.031
oocyte construction GO:0007308 2 0.031
ribonucleoside catabolic process GO:0042454 77 0.031
ovulation GO:0030728 33 0.030
nucleobase containing small molecule metabolic process GO:0055086 115 0.030
cellular component morphogenesis GO:0032989 318 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.030
behavior GO:0007610 527 0.030
ribonucleoside triphosphate catabolic process GO:0009203 72 0.030
germ line stem cell division GO:0042078 9 0.029
macromolecule glycosylation GO:0043413 18 0.029
meiosis i GO:0007127 19 0.028
nucleoside metabolic process GO:0009116 99 0.028
nucleic acid metabolic process GO:0090304 299 0.028
phosphate containing compound metabolic process GO:0006796 232 0.028
cellular response to stress GO:0033554 162 0.028
organophosphate catabolic process GO:0046434 81 0.028
regulation of cellular component organization GO:0051128 248 0.027
Fly
single organism signaling GO:0044700 401 0.027
gene silencing by rna GO:0031047 143 0.027
purine nucleoside monophosphate catabolic process GO:0009128 28 0.027
single organism transport GO:0044765 447 0.026
cytokinetic cell separation GO:0000920 5 0.026
reproductive behavior GO:0019098 387 0.026
positive regulation of chromosome segregation GO:0051984 1 0.026
negative regulation of cellular metabolic process GO:0031324 95 0.026
Fly
positive regulation of molecular function GO:0044093 61 0.026
regulation of cellular catabolic process GO:0031329 51 0.026
Fly
actin filament based process GO:0030029 191 0.026
purine ribonucleoside metabolic process GO:0046128 92 0.026
oocyte axis specification GO:0007309 2 0.026
purine ribonucleotide metabolic process GO:0009150 95 0.026
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.025
establishment of nucleus localization GO:0040023 55 0.025
multi multicellular organism process GO:0044706 390 0.025
purine nucleoside triphosphate catabolic process GO:0009146 72 0.024
cellular component movement GO:0006928 388 0.024
purine ribonucleoside catabolic process GO:0046130 75 0.024
carbohydrate derivative catabolic process GO:1901136 82 0.024
negative regulation of nematode larval development GO:0061064 208 0.024
rna metabolic process GO:0016070 228 0.024
pole plasm assembly GO:0007315 2 0.023
protein complex subunit organization GO:0071822 280 0.023
protein complex assembly GO:0006461 186 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.023
atp metabolic process GO:0046034 42 0.023
glycosyl compound catabolic process GO:1901658 79 0.022
cell proliferation GO:0008283 116 0.022
cellular macromolecular complex assembly GO:0034622 184 0.022
protein modification process GO:0036211 207 0.022
positive regulation of cellular catabolic process GO:0031331 35 0.022
dna recombination GO:0006310 19 0.022
negative regulation of rna biosynthetic process GO:1902679 53 0.022
receptor mediated endocytosis GO:0006898 715 0.022
aromatic compound catabolic process GO:0019439 116 0.022
nucleus organization GO:0006997 38 0.021
rna interference GO:0016246 137 0.021
positive regulation of catabolic process GO:0009896 38 0.021
dna conformation change GO:0071103 11 0.021
ribonucleoside metabolic process GO:0009119 98 0.021
regulation of small gtpase mediated signal transduction GO:0051056 41 0.021
establishment of organelle localization GO:0051656 123 0.021
ribonucleoside triphosphate metabolic process GO:0009199 87 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.021
protein complex biogenesis GO:0070271 186 0.020
regulation of apoptotic signaling pathway GO:2001233 1 0.020
regulation of cell proliferation GO:0042127 105 0.020
multi organism behavior GO:0051705 389 0.020
negative regulation of transcription dna templated GO:0045892 53 0.020
cellular amine metabolic process GO:0044106 15 0.020
cellular component assembly involved in morphogenesis GO:0010927 183 0.020
cellular protein metabolic process GO:0044267 279 0.020
Fly
cellular nitrogen compound catabolic process GO:0044270 119 0.020
regulation of nematode larval development GO:0061062 260 0.019
catabolic process GO:0009056 318 0.019
Fly
cellular biosynthetic process GO:0044249 315 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
neuron projection morphogenesis GO:0048812 114 0.019
negative regulation of cell cycle GO:0045786 53 0.019
Human Fly
ribonucleotide catabolic process GO:0009261 75 0.019
signal transduction GO:0007165 317 0.019
purine nucleoside catabolic process GO:0006152 75 0.018
purine nucleotide catabolic process GO:0006195 75 0.018
cellular response to abiotic stimulus GO:0071214 4 0.018
signaling GO:0023052 401 0.018
positive regulation of cellular protein catabolic process GO:1903364 3 0.018
regulation of localization GO:0032879 194 0.018
regulation of sister chromatid segregation GO:0033045 16 0.018
Fly
actomyosin structure organization GO:0031032 154 0.018
spindle organization GO:0007051 92 0.018
regulation of protein serine threonine kinase activity GO:0071900 18 0.018
negative regulation of developmental process GO:0051093 227 0.018
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.017
Fly
positive regulation of hydrolase activity GO:0051345 38 0.017
negative regulation of neurogenesis GO:0050768 4 0.017
fertilization GO:0009566 63 0.017
regulation of hydrolase activity GO:0051336 45 0.017
small gtpase mediated signal transduction GO:0007264 32 0.017
nucleoside triphosphate catabolic process GO:0009143 72 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
positive regulation of protein metabolic process GO:0051247 45 0.016
meiotic cytokinesis GO:0033206 15 0.016
carboxylic acid metabolic process GO:0019752 34 0.016
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.016
nucleotide metabolic process GO:0009117 108 0.016
cellular protein complex assembly GO:0043623 178 0.016
chemotaxis GO:0006935 120 0.016
negative regulation of post embryonic development GO:0048581 208 0.015
regulation of protein metabolic process GO:0051246 81 0.015
Fly
rna transport GO:0050658 3 0.015
oxoacid metabolic process GO:0043436 47 0.015
digestive tract morphogenesis GO:0048546 76 0.015
taxis GO:0042330 128 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
organic acid metabolic process GO:0006082 47 0.015
cell cycle g1 s phase transition GO:0044843 2 0.015
atp catabolic process GO:0006200 27 0.015
response to abiotic stimulus GO:0009628 152 0.015
microtubule based process GO:0007017 182 0.015
organic substance biosynthetic process GO:1901576 323 0.015
regulation of mitosis GO:0007088 18 0.015
Fly
regulation of cellular metabolic process GO:0031323 305 0.015
Fly
cell cycle phase transition GO:0044770 19 0.015
Human Fly
regulation of atp catabolic process GO:1903289 3 0.015
nucleobase containing compound catabolic process GO:0034655 114 0.014
regulation of nitrogen compound metabolic process GO:0051171 222 0.014
regulation of atpase activity GO:0043462 3 0.014
muscle cell development GO:0055001 158 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
single organism membrane organization GO:0044802 35 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.014
regulation of cell development GO:0060284 49 0.014
positive regulation of cell death GO:0010942 38 0.014
regulation of cytoskeleton organization GO:0051493 41 0.014
regulation of locomotion GO:0040012 161 0.014
regulation of apoptotic process GO:0042981 36 0.013
regulation of purine nucleotide catabolic process GO:0033121 35 0.013
dna duplex unwinding GO:0032508 3 0.013
regulation of protein modification process GO:0031399 46 0.013
macromolecule biosynthetic process GO:0009059 250 0.013
nucleoside triphosphate metabolic process GO:0009141 87 0.013
regulation of meiotic cell cycle GO:0051445 136 0.013
amine metabolic process GO:0009308 15 0.013
regulation of multicellular organismal development GO:2000026 317 0.013
pattern specification process GO:0007389 59 0.013
heterocycle catabolic process GO:0046700 119 0.013
proteolysis GO:0006508 61 0.013
Fly
regulation of cell cycle GO:0051726 194 0.013
Human Fly
regulation of protein kinase activity GO:0045859 28 0.013
nucleus localization GO:0051647 55 0.013
muscle structure development GO:0061061 191 0.013
cellular protein localization GO:0034613 75 0.013
regulation of biosynthetic process GO:0009889 189 0.013
regulation of dna metabolic process GO:0051052 14 0.013
g1 s transition of mitotic cell cycle GO:0000082 2 0.013
positive regulation of transferase activity GO:0051347 21 0.013
macromolecule modification GO:0043412 218 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.013
protein oligomerization GO:0051259 4 0.012
biosynthetic process GO:0009058 323 0.012
negative regulation of chromosome segregation GO:0051985 4 0.012
Fly
muscle cell differentiation GO:0042692 171 0.012
regulation of dna replication GO:0006275 5 0.012
proteasomal protein catabolic process GO:0010498 20 0.012
Fly
meiotic sister chromatid segregation GO:0045144 15 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
Fly
establishment of spindle orientation GO:0051294 34 0.012
ribonucleoside monophosphate catabolic process GO:0009158 28 0.012
sensory organ morphogenesis GO:0090596 2 0.012
synapsis GO:0007129 10 0.012
negative regulation of cellular biosynthetic process GO:0031327 65 0.012
cellular ketone metabolic process GO:0042180 14 0.012
developmental maturation GO:0021700 26 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.012
organophosphate metabolic process GO:0019637 125 0.012
regulation of neuromuscular synaptic transmission GO:1900073 1 0.012
regulation of cell communication GO:0010646 176 0.012
defense response to bacterium GO:0042742 86 0.011
regulation of transcription dna templated GO:0006355 164 0.011
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.011
regulation of actin filament based process GO:0032970 22 0.011
protein modification by small protein conjugation or removal GO:0070647 40 0.011
purine ribonucleotide catabolic process GO:0009154 75 0.011
attachment of mitotic spindle microtubules to kinetochore GO:0051315 6 0.011
negative regulation of cellular process GO:0048523 239 0.011
Human Fly
nucleoside monophosphate metabolic process GO:0009123 46 0.011
regulation of purine nucleotide metabolic process GO:1900542 37 0.011
positive regulation of phosphorus metabolic process GO:0010562 56 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
positive regulation of apoptotic process GO:0043065 17 0.011
apoptotic cell clearance GO:0043277 111 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
positive regulation of cellular metabolic process GO:0031325 178 0.011
single organism cellular localization GO:1902580 72 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.011
cellular response to dna damage stimulus GO:0006974 41 0.011
establishment of rna localization GO:0051236 3 0.011
regulation of meiosis GO:0040020 94 0.011
negative regulation of cellular catabolic process GO:0031330 9 0.011
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.011
chromosome separation GO:0051304 19 0.011
Fly
regulation of catalytic activity GO:0050790 78 0.011
protein localization GO:0008104 205 0.011
regulation of nucleotide catabolic process GO:0030811 35 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
stem cell division GO:0017145 18 0.010
positive regulation of cell cycle GO:0045787 55 0.010
somatic muscle development GO:0007525 1 0.010
positive regulation of neurogenesis GO:0050769 4 0.010
organic substance transport GO:0071702 113 0.010
collagen and cuticulin based cuticle development GO:0040002 99 0.010

zwl-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
reproductive organ cancer DOID:193 0 0.011
female reproductive organ cancer DOID:120 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011