Caenorhabditis elegans

43 known processes

pig-1 (CELE_W03G1.6)

Protein PIG-1

pig-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ development GO:0048513 1102 0.734
Zebrafish
embryo development GO:0009790 3052 0.722
genitalia development GO:0048806 741 0.645
organelle organization GO:0006996 783 0.631
cell motility GO:0048870 313 0.541
reproductive system development GO:0061458 850 0.516
reproductive structure development GO:0048608 850 0.459
development of primary sexual characteristics GO:0045137 840 0.418
cellular component movement GO:0006928 388 0.377
positive regulation of cellular process GO:0048522 332 0.376
Mouse Worm
locomotion GO:0040011 1634 0.376
sex differentiation GO:0007548 909 0.349
hermaphrodite genitalia development GO:0040035 734 0.310
cell cycle process GO:0022402 482 0.306
Worm
localization of cell GO:0051674 313 0.296
developmental process involved in reproduction GO:0003006 1165 0.265
embryo development ending in birth or egg hatching GO:0009792 2992 0.265
regulation of multicellular organismal process GO:0051239 726 0.262
Zebrafish Worm
signal transduction GO:0007165 317 0.255
Mouse
cell migration GO:0016477 306 0.239
transport GO:0006810 1093 0.227
negative regulation of cellular process GO:0048523 239 0.223
Worm
meiotic nuclear division GO:0007126 300 0.216
protein phosphorylation GO:0006468 85 0.207
Human Mouse Worm
positive regulation of macromolecule metabolic process GO:0010604 149 0.205
single organism reproductive process GO:0044702 1196 0.204
reproductive behavior GO:0019098 387 0.198
meiotic cell cycle process GO:1903046 170 0.198
regulation of macromolecule metabolic process GO:0060255 421 0.195
establishment of localization GO:0051234 1171 0.192
gonad development GO:0008406 840 0.189
regulation of primary metabolic process GO:0080090 292 0.188
multicellular organismal reproductive behavior GO:0033057 384 0.180
meiotic cell cycle GO:0051321 335 0.178
Worm
positive regulation of neurogenesis GO:0050769 4 0.170
protein metabolic process GO:0019538 422 0.169
Human Mouse Worm
single organism organelle organization GO:1902589 501 0.159
post embryonic development GO:0009791 2152 0.156
body morphogenesis GO:0010171 620 0.155
regulation of vulval development GO:0040028 248 0.148
mitotic cell cycle process GO:1903047 194 0.146
small gtpase mediated signal transduction GO:0007264 32 0.146
positive regulation of developmental process GO:0051094 408 0.142
Worm
cellular protein modification process GO:0006464 207 0.137
Human Mouse Worm
protein modification process GO:0036211 207 0.136
Human Mouse Worm
transcription dna templated GO:0006351 168 0.136
nervous system development GO:0007399 253 0.136
rna metabolic process GO:0016070 228 0.135
oviposition GO:0018991 364 0.134
positive regulation of catalytic activity GO:0043085 59 0.131
post embryonic organ development GO:0048569 336 0.127
vulval development GO:0040025 333 0.125
multicellular organismal reproductive process GO:0048609 815 0.125
multicellular organism reproduction GO:0032504 819 0.124
digestive tract development GO:0048565 122 0.123
regulation of meiotic cell cycle GO:0051445 136 0.121
Worm
digestive system development GO:0055123 122 0.119
regulation of nitrogen compound metabolic process GO:0051171 222 0.119
signaling GO:0023052 401 0.117
Mouse
negative regulation of biological process GO:0048519 567 0.117
Worm
multi multicellular organism process GO:0044706 390 0.114
rho protein signal transduction GO:0007266 2 0.113
regulation of metabolic process GO:0019222 478 0.112
aromatic compound biosynthetic process GO:0019438 192 0.112
generation of neurons GO:0048699 235 0.110
microtubule based process GO:0007017 182 0.110
neuron development GO:0048666 199 0.107
neurogenesis GO:0022008 236 0.107
ras protein signal transduction GO:0007265 31 0.106
regulation of nematode larval development GO:0061062 260 0.105
Worm
behavior GO:0007610 527 0.104
cellular protein metabolic process GO:0044267 279 0.103
Human Mouse Worm
inductive cell migration GO:0040039 145 0.102
cell cycle GO:0007049 526 0.100
Worm
regulation of transcription dna templated GO:0006355 164 0.100
growth GO:0040007 562 0.098
stem cell proliferation GO:0072089 9 0.097
heterocycle biosynthetic process GO:0018130 187 0.095
tube development GO:0035295 126 0.093
negative regulation of transcription dna templated GO:0045892 53 0.090
macromolecule modification GO:0043412 218 0.088
Human Mouse Worm
regulation of axonogenesis GO:0050770 24 0.087
single organism cellular localization GO:1902580 72 0.085
regulation of developmental process GO:0050793 684 0.084
Worm
regulation of gene expression GO:0010468 366 0.083
multi organism behavior GO:0051705 389 0.083
macromolecule localization GO:0033036 771 0.082
organelle fission GO:0048285 363 0.082
negative regulation of vulval development GO:0040027 206 0.081
cell division GO:0051301 262 0.081
embryonic morphogenesis GO:0048598 152 0.080
regulation of cellular metabolic process GO:0031323 305 0.080
cell surface receptor signaling pathway GO:0007166 149 0.079
single organism localization GO:1902578 518 0.078
regulation of cell division GO:0051302 142 0.076
cell projection morphogenesis GO:0048858 148 0.076
cytoskeleton organization GO:0007010 339 0.075
cell development GO:0048468 696 0.074
Zebrafish
regulation of signaling GO:0023051 172 0.072
macromolecular complex subunit organization GO:0043933 320 0.071
lipid localization GO:0010876 573 0.071
macromolecule biosynthetic process GO:0009059 250 0.071
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.071
positive regulation of cell migration GO:0030335 3 0.070
protein catabolic process GO:0030163 162 0.068
positive regulation of metabolic process GO:0009893 187 0.068
wnt signaling pathway GO:0016055 27 0.066
single organism signaling GO:0044700 401 0.066
Mouse
regulation of catalytic activity GO:0050790 78 0.066
cell part morphogenesis GO:0032990 152 0.066
receptor mediated endocytosis GO:0006898 715 0.065
protein complex biogenesis GO:0070271 186 0.065
multi organism reproductive behavior GO:0044705 387 0.065
phosphorus metabolic process GO:0006793 232 0.065
Human Mouse Worm
cellular biosynthetic process GO:0044249 315 0.065
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.065
organic cyclic compound biosynthetic process GO:1901362 195 0.064
head development GO:0060322 1 0.064
digestive tract morphogenesis GO:0048546 76 0.063
cell morphogenesis GO:0000902 163 0.063
spindle organization GO:0007051 92 0.063
phosphate containing compound metabolic process GO:0006796 232 0.061
Human Mouse Worm
cellular localization GO:0051641 360 0.061
neuron projection development GO:0031175 187 0.061
regulation of cell communication GO:0010646 176 0.061
regulation of developmental growth GO:0048638 389 0.060
developmental growth GO:0048589 412 0.060
regulation of biological quality GO:0065008 741 0.060
Zebrafish
negative regulation of multicellular organismal process GO:0051241 236 0.060
regulation of multicellular organism growth GO:0040014 373 0.058
positive regulation of multicellular organismal process GO:0051240 417 0.058
Worm
regulation of anatomical structure size GO:0090066 46 0.057
cellular macromolecule localization GO:0070727 75 0.057
death GO:0016265 547 0.057
regulation of growth GO:0040008 409 0.056
negative regulation of wnt signaling pathway GO:0030178 6 0.056
maintenance of location GO:0051235 580 0.056
regulation of cellular component size GO:0032535 40 0.055
actin cytoskeleton organization GO:0030036 184 0.054
regulation of transferase activity GO:0051338 31 0.054
nucleic acid templated transcription GO:0097659 169 0.054
gene expression GO:0010467 412 0.054
sensory organ morphogenesis GO:0090596 2 0.053
regulation of cell differentiation GO:0045595 81 0.053
endocytosis GO:0006897 819 0.052
multicellular organismal aging GO:0010259 812 0.052
Worm
negative regulation of neurogenesis GO:0050768 4 0.052
apoptotic process GO:0006915 478 0.051
lipid storage GO:0019915 565 0.051
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.051
biosynthetic process GO:0009058 323 0.050
cell death GO:0008219 547 0.050
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.050
regulation of organelle organization GO:0033043 164 0.050
neuroblast proliferation GO:0007405 9 0.049
positive regulation of cytokinesis GO:0032467 3 0.048
cellular protein localization GO:0034613 75 0.048
vesicle mediated transport GO:0016192 852 0.048
response to external biotic stimulus GO:0043207 101 0.048
programmed cell death GO:0012501 500 0.048
regulation of molecular function GO:0065009 89 0.047
regulation of protein kinase activity GO:0045859 28 0.047
multi organism reproductive process GO:0044703 867 0.046
actin filament based process GO:0030029 191 0.046
regulation of neurogenesis GO:0050767 40 0.046
regulation of small gtpase mediated signal transduction GO:0051056 41 0.045
tube morphogenesis GO:0035239 79 0.045
neuron differentiation GO:0030182 217 0.045
regulation of rna metabolic process GO:0051252 173 0.045
axon development GO:0061564 163 0.044
regulation of kinase activity GO:0043549 29 0.043
gastrulation GO:0007369 58 0.043
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.042
regulation of cell cycle process GO:0010564 145 0.042
single organism transport GO:0044765 447 0.041
negative regulation of gene expression GO:0010629 217 0.041
cell fate commitment GO:0045165 139 0.041
canonical wnt signaling pathway GO:0060070 3 0.040
regulation of gene expression epigenetic GO:0040029 163 0.040
regulation of phosphate metabolic process GO:0019220 81 0.040
regulation of cytokinesis GO:0032465 10 0.039
regulation of cell morphogenesis GO:0022604 40 0.039
cell projection organization GO:0030030 231 0.039
macromolecular complex assembly GO:0065003 193 0.038
cell proliferation GO:0008283 116 0.038
regulation of cell proliferation GO:0042127 105 0.038
Worm
defense response GO:0006952 296 0.037
organic substance catabolic process GO:1901575 294 0.037
positive regulation of locomotion GO:0040017 42 0.036
regulation of rna biosynthetic process GO:2001141 165 0.036
neuron projection morphogenesis GO:0048812 114 0.036
rna biosynthetic process GO:0032774 169 0.036
anatomical structure formation involved in morphogenesis GO:0048646 250 0.035
regulation of neuron projection development GO:0010975 31 0.035
positive regulation of gtpase activity GO:0043547 28 0.035
protein complex assembly GO:0006461 186 0.035
asymmetric neuroblast division GO:0055059 8 0.035
developmental growth involved in morphogenesis GO:0060560 37 0.035
regulation of signal transduction GO:0009966 135 0.034
multicellular organism growth GO:0035264 385 0.034
positive regulation of cell cycle GO:0045787 55 0.034
Worm
positive regulation of protein kinase activity GO:0045860 18 0.034
positive regulation of multicellular organism growth GO:0040018 352 0.033
cell type specific apoptotic process GO:0097285 4 0.033
positive regulation of cellular metabolic process GO:0031325 178 0.033
protein complex subunit organization GO:0071822 280 0.032
regulation of cell cycle GO:0051726 194 0.032
Worm
oogenesis GO:0048477 229 0.032
cellular component assembly GO:0022607 293 0.031
regulation of response to stimulus GO:0048583 243 0.031
negative regulation of signal transduction GO:0009968 60 0.031
chromatin modification GO:0016568 32 0.031
intracellular signal transduction GO:0035556 96 0.030
Mouse
negative regulation of developmental process GO:0051093 227 0.030
positive regulation of neuron differentiation GO:0045666 4 0.030
positive regulation of growth GO:0045927 369 0.030
response to chemical GO:0042221 356 0.030
Mouse
meiotic chromosome segregation GO:0045132 139 0.029
positive regulation of molecular function GO:0044093 61 0.029
regulation of multicellular organismal development GO:2000026 317 0.029
Worm
sexual reproduction GO:0019953 546 0.028
regulation of cytoplasmic transport GO:1903649 3 0.028
regulation of nucleic acid templated transcription GO:1903506 165 0.028
regulation of post embryonic development GO:0048580 260 0.028
Worm
negative regulation of metabolic process GO:0009892 240 0.028
positive regulation of developmental growth GO:0048639 354 0.028
regulation of meiosis GO:0040020 94 0.028
regulation of cell development GO:0060284 49 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.027
positive regulation of signal transduction GO:0009967 40 0.026
aging GO:0007568 812 0.026
Worm
regulation of cell projection organization GO:0031344 38 0.026
guanosine containing compound metabolic process GO:1901068 49 0.026
actomyosin contractile ring organization GO:0044837 1 0.026
immune response GO:0006955 192 0.026
regulation of intracellular signal transduction GO:1902531 77 0.025
protein localization GO:0008104 205 0.025
mitotic spindle organization GO:0007052 81 0.025
cellular nitrogen compound biosynthetic process GO:0044271 192 0.025
organonitrogen compound metabolic process GO:1901564 151 0.025
regulation of neuron differentiation GO:0045664 40 0.025
regulation of phosphorylation GO:0042325 45 0.024
phosphorylation GO:0016310 116 0.024
Human Mouse Worm
negative regulation of post embryonic development GO:0048581 208 0.024
cell morphogenesis involved in differentiation GO:0000904 112 0.024
positive regulation of post embryonic development GO:0048582 54 0.024
Worm
macromolecule catabolic process GO:0009057 202 0.024
cytokinetic process GO:0032506 10 0.024
cellular component morphogenesis GO:0032989 318 0.024
regulation of ras protein signal transduction GO:0046578 41 0.023
nucleobase containing compound biosynthetic process GO:0034654 184 0.023
regulation of canonical wnt signaling pathway GO:0060828 1 0.023
response to biotic stimulus GO:0009607 101 0.023
positive regulation of nucleic acid templated transcription GO:1903508 102 0.023
nucleobase containing compound metabolic process GO:0006139 406 0.023
nematode male tail tip morphogenesis GO:0045138 77 0.023
chromosome segregation GO:0007059 180 0.023
female meiotic division GO:0007143 17 0.022
covalent chromatin modification GO:0016569 30 0.022
positive regulation of gtp catabolic process GO:0033126 28 0.022
negative regulation of cell communication GO:0010648 61 0.022
regulation of gtp catabolic process GO:0033124 32 0.022
regulation of nuclear division GO:0051783 115 0.022
regulation of biosynthetic process GO:0009889 189 0.022
negative regulation of nematode larval development GO:0061064 208 0.022
cellular response to stress GO:0033554 162 0.021
Mouse
establishment of localization in cell GO:0051649 318 0.021
regulation of actin filament based process GO:0032970 22 0.021
developmental cell growth GO:0048588 39 0.021
regulation of cytoskeleton organization GO:0051493 41 0.021
nucleic acid metabolic process GO:0090304 299 0.021
cellular macromolecule biosynthetic process GO:0034645 247 0.021
organelle assembly GO:0070925 214 0.021
regulation of nervous system development GO:0051960 41 0.021
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.020
negative regulation of response to stimulus GO:0048585 73 0.020
neuron recognition GO:0008038 83 0.020
innate immune response GO:0045087 190 0.020
catabolic process GO:0009056 318 0.020
positive regulation of neuron projection development GO:0010976 4 0.020
regulation of cell migration GO:0030334 55 0.020
taxis GO:0042330 128 0.020
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 1 0.020
negative regulation of nucleic acid templated transcription GO:1903507 53 0.020
negative regulation of signaling GO:0023057 61 0.019
regulation of phosphorus metabolic process GO:0051174 81 0.019
actomyosin structure organization GO:0031032 154 0.019
axonogenesis GO:0007409 102 0.019
regulation of anatomical structure morphogenesis GO:0022603 51 0.019
regulation of organ morphogenesis GO:2000027 4 0.019
regulation of cell size GO:0008361 30 0.019
regulation of localization GO:0032879 194 0.019
positive regulation of transcription dna templated GO:0045893 102 0.019
positive regulation of cellular catabolic process GO:0031331 35 0.019
cytokinesis GO:0000910 80 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
regulation of cell shape GO:0008360 6 0.018
centromere complex assembly GO:0034508 5 0.018
chromatin assembly or disassembly GO:0006333 1 0.018
determination of adult lifespan GO:0008340 812 0.018
Worm
regulation of protein serine threonine kinase activity GO:0071900 18 0.018
negative regulation of macromolecule metabolic process GO:0010605 229 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of filopodium assembly GO:0051489 2 0.017
regulation of catabolic process GO:0009894 57 0.017
positive regulation of phosphate metabolic process GO:0045937 56 0.017
cuticle development GO:0042335 100 0.017
regulation of nucleoside metabolic process GO:0009118 37 0.017
regulation of protein metabolic process GO:0051246 81 0.017
regulation of cellular biosynthetic process GO:0031326 189 0.017
asymmetric cell division GO:0008356 36 0.017
positive regulation of ras gtpase activity GO:0032320 19 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.017
regulation of cellular component organization GO:0051128 248 0.017
regulation of gtpase activity GO:0043087 30 0.017
positive regulation of phosphorus metabolic process GO:0010562 56 0.016
response to external stimulus GO:0009605 289 0.016
response to other organism GO:0051707 101 0.016
cellular component biogenesis GO:0044085 297 0.016
proteolysis GO:0006508 61 0.016
carboxylic acid metabolic process GO:0019752 34 0.016
positive regulation of nucleoside metabolic process GO:0045979 28 0.016
regulation of nucleocytoplasmic transport GO:0046822 3 0.016
amine metabolic process GO:0009308 15 0.016
guanosine containing compound catabolic process GO:1901069 48 0.015
gtp catabolic process GO:0006184 46 0.015
regulation of protein targeting GO:1903533 3 0.015
internal peptidyl lysine acetylation GO:0018393 3 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.015
cellular amine metabolic process GO:0044106 15 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.015
regulation of purine nucleotide catabolic process GO:0033121 35 0.015
cellular protein complex assembly GO:0043623 178 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.015
regulation of macromolecule biosynthetic process GO:0010556 189 0.014
male anatomical structure morphogenesis GO:0090598 78 0.014
activation of protein kinase activity GO:0032147 11 0.014
cellular response to abiotic stimulus GO:0071214 4 0.014
negative regulation of rna biosynthetic process GO:1902679 53 0.014
asymmetric protein localization GO:0008105 35 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.014
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.014
positive regulation of cdc42 gtpase activity GO:0043089 3 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
germ cell development GO:0007281 351 0.014
positive regulation of cellular protein catabolic process GO:1903364 3 0.014
regulation of cellular catabolic process GO:0031329 51 0.014
regulation of cell death GO:0010941 65 0.014
Mouse
positive regulation of kinase activity GO:0033674 19 0.014
negative regulation of neuron differentiation GO:0045665 4 0.014
chemotaxis GO:0006935 120 0.014
axon guidance GO:0007411 82 0.013
transcription from rna polymerase ii promoter GO:0006366 149 0.013
chromatin assembly GO:0031497 1 0.013
positive regulation of nucleotide catabolic process GO:0030813 28 0.013
regulation of behavior GO:0050795 97 0.013
neuron projection extension GO:1990138 37 0.013
male sex differentiation GO:0046661 86 0.013
regulation of protein localization GO:0032880 50 0.013
positive regulation of catabolic process GO:0009896 38 0.013
mesodermal cell migration GO:0008078 9 0.013
small molecule metabolic process GO:0044281 186 0.013
negative regulation of cellular biosynthetic process GO:0031327 65 0.012
regulation of protein modification process GO:0031399 46 0.012
regulation of locomotion GO:0040012 161 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
muscle structure development GO:0061061 191 0.012
microtubule based movement GO:0007018 33 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.012
regulation of purine nucleotide metabolic process GO:1900542 37 0.012
regulation of dna templated transcription in response to stress GO:0043620 3 0.012
tissue morphogenesis GO:0048729 65 0.012
response to wounding GO:0009611 4 0.012
organic acid metabolic process GO:0006082 47 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
gamete generation GO:0007276 461 0.012
positive regulation of protein modification process GO:0031401 29 0.012
gene silencing GO:0016458 143 0.011
regulation of cell motility GO:2000145 57 0.011
negative regulation of chromosome segregation GO:0051985 4 0.011
regulation of reproductive process GO:2000241 66 0.011
histone modification GO:0016570 30 0.011
positive regulation of intracellular transport GO:0032388 2 0.011
defense response to other organism GO:0098542 100 0.011
somatic stem cell division GO:0048103 9 0.011
male gamete generation GO:0048232 41 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
cellular ketone metabolic process GO:0042180 14 0.011
positive regulation of protein transport GO:0051222 4 0.011
gtp metabolic process GO:0046039 46 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
chromatin remodeling GO:0006338 2 0.011
cellular response to organic substance GO:0071310 119 0.011
positive regulation of nucleotide metabolic process GO:0045981 28 0.011
establishment of cell polarity GO:0030010 46 0.011
cell growth GO:0016049 44 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
protein localization to organelle GO:0033365 37 0.011
axonal defasciculation GO:0007414 1 0.011
cell cycle g1 s phase transition GO:0044843 2 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
sister chromatid segregation GO:0000819 46 0.011
meiosis i GO:0007127 19 0.011
spermatogenesis GO:0007283 41 0.011
mitotic sister chromatid segregation GO:0000070 38 0.011
enzyme linked receptor protein signaling pathway GO:0007167 50 0.010
oxoacid metabolic process GO:0043436 47 0.010
positive regulation of cell projection organization GO:0031346 4 0.010
axonal fasciculation GO:0007413 79 0.010
system process GO:0003008 136 0.010
Zebrafish
organic substance biosynthetic process GO:1901576 323 0.010
peptidyl lysine acetylation GO:0018394 3 0.010
regulation of wnt signaling pathway GO:0030111 9 0.010
organelle localization GO:0051640 127 0.010

pig-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017