Caenorhabditis elegans

60 known processes

lin-2 (CELE_F17E5.1)

Protein LIN-2

lin-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
developmental process involved in reproduction GO:0003006 1165 0.572
Fly
organ development GO:0048513 1102 0.525
signaling GO:0023052 401 0.511
Fly
organic substance biosynthetic process GO:1901576 323 0.474
Mouse
biosynthetic process GO:0009058 323 0.446
Mouse
cell development GO:0048468 696 0.403
Fly
heterocycle biosynthetic process GO:0018130 187 0.352
Mouse
multi organism reproductive process GO:0044703 867 0.324
small molecule metabolic process GO:0044281 186 0.323
cellular biosynthetic process GO:0044249 315 0.319
Mouse
regulation of developmental process GO:0050793 684 0.299
negative regulation of biological process GO:0048519 567 0.256
Human
multicellular organismal aging GO:0010259 812 0.248
regulation of multicellular organismal process GO:0051239 726 0.240
aging GO:0007568 812 0.234
protein localization to basolateral plasma membrane GO:1903361 7 0.230
regulation of nitrogen compound metabolic process GO:0051171 222 0.226
Mouse
cellular macromolecule biosynthetic process GO:0034645 247 0.226
Mouse
vulval development GO:0040025 333 0.210
anatomical structure formation involved in morphogenesis GO:0048646 250 0.208
phosphate containing compound metabolic process GO:0006796 232 0.206
Fly
organelle organization GO:0006996 783 0.199
determination of adult lifespan GO:0008340 812 0.199
regulation of macromolecule biosynthetic process GO:0010556 189 0.192
Mouse
single organism reproductive process GO:0044702 1196 0.191
Fly
phosphorus metabolic process GO:0006793 232 0.174
Fly
regulation of nematode larval development GO:0061062 260 0.174
membrane organization GO:0061024 135 0.174
ribonucleotide metabolic process GO:0009259 99 0.169
regulation of metabolic process GO:0019222 478 0.164
Mouse
cellular component assembly GO:0022607 293 0.156
Fly
cell cycle GO:0007049 526 0.146
single organism transport GO:0044765 447 0.145
Mouse Fly
aromatic compound biosynthetic process GO:0019438 192 0.143
Mouse
post embryonic organ development GO:0048569 336 0.142
macromolecule biosynthetic process GO:0009059 250 0.141
Mouse
establishment of localization GO:0051234 1171 0.135
Mouse Rat Fly
sexual reproduction GO:0019953 546 0.129
Fly
neuron development GO:0048666 199 0.123
endocytosis GO:0006897 819 0.122
Fly
reproductive behavior GO:0019098 387 0.120
regulation of primary metabolic process GO:0080090 292 0.120
Mouse
single organism localization GO:1902578 518 0.116
gene expression GO:0010467 412 0.114
Mouse
nucleobase containing compound metabolic process GO:0006139 406 0.109
Mouse
cellular component biogenesis GO:0044085 297 0.109
Fly
actin filament based process GO:0030029 191 0.107
response to organic substance GO:0010033 131 0.105
Human
single organism signaling GO:0044700 401 0.103
Fly
purine nucleoside metabolic process GO:0042278 92 0.101
vesicle mediated transport GO:0016192 852 0.101
Fly
death GO:0016265 547 0.099
carbohydrate derivative metabolic process GO:1901135 141 0.097
nucleobase containing compound biosynthetic process GO:0034654 184 0.097
Mouse
transport GO:0006810 1093 0.096
Mouse Rat Fly
regulation of multicellular organismal development GO:2000026 317 0.091
ribonucleoside triphosphate metabolic process GO:0009199 87 0.090
receptor mediated endocytosis GO:0006898 715 0.089
sex differentiation GO:0007548 909 0.087
purine nucleotide catabolic process GO:0006195 75 0.087
multi multicellular organism process GO:0044706 390 0.087
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.086
Fly
multicellular organism reproduction GO:0032504 819 0.085
single organism organelle organization GO:1902589 501 0.085
organonitrogen compound metabolic process GO:1901564 151 0.082
nucleobase containing compound catabolic process GO:0034655 114 0.082
regulation of post embryonic development GO:0048580 260 0.081
nucleic acid templated transcription GO:0097659 169 0.081
Mouse
purine nucleotide metabolic process GO:0006163 95 0.081
nucleoside phosphate metabolic process GO:0006753 108 0.080
nucleotide metabolic process GO:0009117 108 0.079
body morphogenesis GO:0010171 620 0.079
ribose phosphate metabolic process GO:0019693 99 0.079
regulation of vulval development GO:0040028 248 0.079
rna metabolic process GO:0016070 228 0.078
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.078
Mouse
cell surface receptor signaling pathway GO:0007166 149 0.077
negative regulation of metabolic process GO:0009892 240 0.077
regulation of gene expression GO:0010468 366 0.077
Mouse
response to chemical GO:0042221 356 0.075
Human
purine ribonucleoside metabolic process GO:0046128 92 0.074
negative regulation of cellular process GO:0048523 239 0.073
Human
cell projection morphogenesis GO:0048858 148 0.072
behavior GO:0007610 527 0.072
phagocytosis GO:0006909 115 0.071
regulation of biological quality GO:0065008 741 0.070
Fly
regulation of molecular function GO:0065009 89 0.070
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.070
cellular protein metabolic process GO:0044267 279 0.069
Fly
maintenance of location GO:0051235 580 0.069
multicellular organismal reproductive process GO:0048609 815 0.068
signal transduction GO:0007165 317 0.068
lipid storage GO:0019915 565 0.066
nucleoside metabolic process GO:0009116 99 0.066
post embryonic development GO:0009791 2152 0.066
protein modification process GO:0036211 207 0.065
Fly
lipid localization GO:0010876 573 0.063
positive regulation of developmental process GO:0051094 408 0.063
regulation of cellular metabolic process GO:0031323 305 0.063
Mouse
purine containing compound metabolic process GO:0072521 95 0.062
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.062
regulation of rna biosynthetic process GO:2001141 165 0.062
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 192 0.062
Mouse
regulation of cellular component organization GO:0051128 248 0.062
Fly
cell death GO:0008219 547 0.062
positive regulation of nematode larval development GO:0061063 54 0.062
cell projection organization GO:0030030 231 0.062
multicellular organismal reproductive behavior GO:0033057 384 0.061
apoptotic process GO:0006915 478 0.061
protein metabolic process GO:0019538 422 0.060
Fly
regulation of purine nucleotide catabolic process GO:0033121 35 0.060
nervous system development GO:0007399 253 0.058
Fly
positive regulation of cellular process GO:0048522 332 0.058
Mouse Fly
single organism carbohydrate metabolic process GO:0044723 29 0.058
negative regulation of macromolecule metabolic process GO:0010605 229 0.057
organonitrogen compound catabolic process GO:1901565 90 0.057
regulation of cell differentiation GO:0045595 81 0.057
positive regulation of multicellular organismal process GO:0051240 417 0.057
cellular component morphogenesis GO:0032989 318 0.056
Fly
cellular catabolic process GO:0044248 199 0.056
cellular component assembly involved in morphogenesis GO:0010927 183 0.056
molting cycle GO:0042303 281 0.055
developmental growth GO:0048589 412 0.055
Fly
organophosphate metabolic process GO:0019637 125 0.055
oogenesis GO:0048477 229 0.054
Fly
purine ribonucleotide metabolic process GO:0009150 95 0.054
purine nucleoside triphosphate metabolic process GO:0009144 87 0.052
guanosine containing compound catabolic process GO:1901069 48 0.052
macromolecule localization GO:0033036 771 0.052
secretion by cell GO:0032940 138 0.051
Fly
negative regulation of biosynthetic process GO:0009890 65 0.051
nucleoside phosphate catabolic process GO:1901292 77 0.051
nucleic acid metabolic process GO:0090304 299 0.050
Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.050
Mouse
negative regulation of gene expression GO:0010629 217 0.049
female gamete generation GO:0007292 254 0.049
Fly
programmed cell death GO:0012501 500 0.049
multi organism reproductive behavior GO:0044705 387 0.049
muscle tissue development GO:0060537 1 0.049
regulation of signaling GO:0023051 172 0.049
Fly
neuron projection development GO:0031175 187 0.049
locomotion GO:0040011 1634 0.048
Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.048
Worm
macromolecule modification GO:0043412 218 0.048
Fly
protein complex assembly GO:0006461 186 0.047
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.046
cell cycle process GO:0022402 482 0.046
cellular response to organic substance GO:0071310 119 0.045
Human
regulation of nucleic acid templated transcription GO:1903506 165 0.044
Mouse
single organism biosynthetic process GO:0044711 91 0.042
secretion GO:0046903 147 0.042
Fly
germ cell development GO:0007281 351 0.042
Fly
purine containing compound catabolic process GO:0072523 75 0.042
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.042
Mouse
glycosyl compound metabolic process GO:1901657 100 0.041
muscle structure development GO:0061061 191 0.041
cellular response to chemical stimulus GO:0070887 129 0.041
Human
cytoskeleton organization GO:0007010 339 0.040
apoptotic cell clearance GO:0043277 111 0.040
nucleoside triphosphate metabolic process GO:0009141 87 0.040
regulation of localization GO:0032879 194 0.039
Mouse Fly
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.039
generation of neurons GO:0048699 235 0.038
nucleoside catabolic process GO:0009164 78 0.038
striated muscle cell differentiation GO:0051146 158 0.038
neuron projection morphogenesis GO:0048812 114 0.037
regulation of synapse assembly GO:0051963 2 0.037
Fly
regulation of biosynthetic process GO:0009889 189 0.037
Mouse
gonad development GO:0008406 840 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.036
ribonucleoside metabolic process GO:0009119 98 0.036
regulation of locomotion GO:0040012 161 0.035
Fly
multi organism behavior GO:0051705 389 0.035
small molecule biosynthetic process GO:0044283 38 0.035
membrane invagination GO:0010324 98 0.035
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.035
Mouse
head development GO:0060322 1 0.035
myofibril assembly GO:0030239 154 0.035
protein localization GO:0008104 205 0.034
muscle cell development GO:0055001 158 0.034
response to wounding GO:0009611 4 0.034
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.033
innate immune response GO:0045087 190 0.033
actin cytoskeleton organization GO:0030036 184 0.033
negative regulation of post embryonic development GO:0048581 208 0.032
ras protein signal transduction GO:0007265 31 0.032
purine ribonucleoside catabolic process GO:0046130 75 0.032
nucleobase containing small molecule metabolic process GO:0055086 115 0.032
tissue development GO:0009888 112 0.032
Fly
oviposition GO:0018991 364 0.032
cellular localization GO:0051641 360 0.032
regulation of rna metabolic process GO:0051252 173 0.031
Mouse
regulation of catalytic activity GO:0050790 78 0.031
posttranscriptional regulation of gene expression GO:0010608 166 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.031
striated muscle cell development GO:0055002 157 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.030
positive regulation of metabolic process GO:0009893 187 0.030
Mouse
protein complex subunit organization GO:0071822 280 0.030
growth GO:0040007 562 0.030
Fly
positive regulation of phosphorus metabolic process GO:0010562 56 0.030
actomyosin structure organization GO:0031032 154 0.030
organophosphate catabolic process GO:0046434 81 0.029
immune response GO:0006955 192 0.029
gamete generation GO:0007276 461 0.029
Fly
reproductive structure development GO:0048608 850 0.029
engulfment of apoptotic cell GO:0043652 94 0.029
establishment of localization in cell GO:0051649 318 0.029
Rat Fly
negative regulation of cellular biosynthetic process GO:0031327 65 0.029
development of primary sexual characteristics GO:0045137 840 0.028
regulation of cell cycle GO:0051726 194 0.028
regulation of growth GO:0040008 409 0.027
Fly
regulation of organelle organization GO:0033043 164 0.027
g protein coupled receptor signaling pathway GO:0007186 46 0.027
gtp catabolic process GO:0006184 46 0.027
negative regulation of cellular metabolic process GO:0031324 95 0.027
skeletal muscle organ development GO:0060538 3 0.027
multicellular organism growth GO:0035264 385 0.027
single organism catabolic process GO:0044712 129 0.027
organic cyclic compound biosynthetic process GO:1901362 195 0.027
Mouse
dendrite development GO:0016358 42 0.026
aromatic compound catabolic process GO:0019439 116 0.026
cell type specific apoptotic process GO:0097285 4 0.026
macromolecular complex assembly GO:0065003 193 0.026
gtp metabolic process GO:0046039 46 0.025
myosin filament assembly GO:0031034 138 0.025
transcription from rna polymerase ii promoter GO:0006366 149 0.025
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 72 0.025
single organism cellular localization GO:1902580 72 0.025
cell part morphogenesis GO:0032990 152 0.025
cellular nitrogen compound catabolic process GO:0044270 119 0.025
oxoacid metabolic process GO:0043436 47 0.024
intracellular signal transduction GO:0035556 96 0.024
negative regulation of developmental process GO:0051093 227 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.023
Mouse
neuron differentiation GO:0030182 217 0.023
defense response GO:0006952 296 0.023
protein complex biogenesis GO:0070271 186 0.023
phagocytosis engulfment GO:0006911 98 0.023
protein oligomerization GO:0051259 4 0.023
regulation of oviposition GO:0046662 43 0.023
muscle cell differentiation GO:0042692 171 0.023
cellular component movement GO:0006928 388 0.022
Fly
cellular protein complex assembly GO:0043623 178 0.022
response to external stimulus GO:0009605 289 0.022
Human
guanosine containing compound metabolic process GO:1901068 49 0.022
heterocycle catabolic process GO:0046700 119 0.022
cellular macromolecular complex assembly GO:0034622 184 0.022
neuromuscular junction development GO:0007528 2 0.022
Fly
cellular ketone metabolic process GO:0042180 14 0.022
protein localization to plasma membrane GO:0072659 7 0.022
regulation of phagocytosis engulfment GO:0060099 17 0.021
organelle assembly GO:0070925 214 0.021
cell division GO:0051301 262 0.021
rna biosynthetic process GO:0032774 169 0.021
Mouse
single organism behavior GO:0044708 83 0.021
Fly
carbohydrate derivative catabolic process GO:1901136 82 0.021
male sex differentiation GO:0046661 86 0.021
regulation of cell communication GO:0010646 176 0.021
Fly
enzyme linked receptor protein signaling pathway GO:0007167 50 0.021
nucleotide catabolic process GO:0009166 77 0.021
neurogenesis GO:0022008 236 0.020
regulation of signal transduction GO:0009966 135 0.020
regulation of cellular protein metabolic process GO:0032268 75 0.020
nematode male tail tip morphogenesis GO:0045138 77 0.020
synaptic transmission GO:0007268 106 0.020
Fly
response to abiotic stimulus GO:0009628 152 0.020
positive regulation of growth GO:0045927 369 0.019
striated muscle myosin thick filament assembly GO:0071688 138 0.019
regulation of meiotic cell cycle GO:0051445 136 0.019
organic acid metabolic process GO:0006082 47 0.019
negative regulation of nematode larval development GO:0061064 208 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.019
regulation of ion transmembrane transport GO:0034765 19 0.019
Mouse
genitalia development GO:0048806 741 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.019
purine ribonucleotide catabolic process GO:0009154 75 0.019
reproductive system development GO:0061458 850 0.018
nucleoside triphosphate catabolic process GO:0009143 72 0.018
rna interference GO:0016246 137 0.018
asymmetric protein localization GO:0008105 35 0.018
embryonic morphogenesis GO:0048598 152 0.018
purine nucleoside catabolic process GO:0006152 75 0.018
glycosyl compound catabolic process GO:1901658 79 0.017
positive regulation of locomotion GO:0040017 42 0.017
transcription dna templated GO:0006351 168 0.017
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 72 0.017
carbohydrate derivative biosynthetic process GO:1901137 46 0.017
small gtpase mediated signal transduction GO:0007264 32 0.017
cytokinesis GO:0000910 80 0.017
negative regulation of transcription dna templated GO:0045892 53 0.017
digestive system development GO:0055123 122 0.016
regulation of multi organism process GO:0043900 69 0.016
regulation of response to stimulus GO:0048583 243 0.016
Human
negative regulation of vulval development GO:0040027 206 0.016
positive regulation of cell migration GO:0030335 3 0.016
cellular protein modification process GO:0006464 207 0.016
Fly
positive regulation of vulval development GO:0040026 52 0.016
regulation of cell cycle process GO:0010564 145 0.016
posttranscriptional gene silencing by rna GO:0035194 143 0.015
cyclic nucleotide biosynthetic process GO:0009190 2 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
Fly
ribonucleoside catabolic process GO:0042454 77 0.015
embryo development GO:0009790 3052 0.015
Worm
establishment of organelle localization GO:0051656 123 0.015
Fly
carbohydrate metabolic process GO:0005975 34 0.015
digestive tract development GO:0048565 122 0.015
nucleoside monophosphate metabolic process GO:0009123 46 0.015
positive regulation of cellular catabolic process GO:0031331 35 0.015
regulation of catabolic process GO:0009894 57 0.015
sensory organ morphogenesis GO:0090596 2 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
cell cell signaling GO:0007267 118 0.014
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.014
Mouse
response to temperature stimulus GO:0009266 66 0.014
negative regulation of rna metabolic process GO:0051253 53 0.014
regulation of anatomical structure morphogenesis GO:0022603 51 0.014
Fly
regulation of developmental growth GO:0048638 389 0.014
Fly
organic substance transport GO:0071702 113 0.014
Rat
regulation of nuclear division GO:0051783 115 0.014
amine metabolic process GO:0009308 15 0.014
gene silencing GO:0016458 143 0.014
cellular response to dna damage stimulus GO:0006974 41 0.014
organic substance catabolic process GO:1901575 294 0.014
mating GO:0007618 34 0.014
Fly
posttranscriptional gene silencing GO:0016441 143 0.014
response to external biotic stimulus GO:0043207 101 0.013
collagen and cuticulin based cuticle development GO:0040002 99 0.013
protein localization to membrane GO:0072657 11 0.013
positive regulation of cell communication GO:0010647 69 0.013
Fly
positive regulation of hydrolase activity GO:0051345 38 0.013
male anatomical structure morphogenesis GO:0090598 78 0.013
regulation of hydrolase activity GO:0051336 45 0.013
hermaphrodite genitalia development GO:0040035 734 0.013
inductive cell migration GO:0040039 145 0.013
organelle localization GO:0051640 127 0.013
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.013
synaptic vesicle localization GO:0097479 22 0.013
Fly
defense response to gram positive bacterium GO:0050830 31 0.013
carboxylic acid metabolic process GO:0019752 34 0.013
localization of cell GO:0051674 313 0.013
Fly
gene silencing by rna GO:0031047 143 0.013
regulation of gene expression epigenetic GO:0040029 163 0.012
regulation of cytoskeleton organization GO:0051493 41 0.012
dauer larval development GO:0040024 92 0.012
response to endoplasmic reticulum stress GO:0034976 71 0.012
cellular amine metabolic process GO:0044106 15 0.012
negative regulation of nucleic acid templated transcription GO:1903507 53 0.012
taxis GO:0042330 128 0.012
lamellipodium assembly GO:0030032 2 0.012
dopamine receptor signaling pathway GO:0007212 11 0.012
positive regulation of phosphate metabolic process GO:0045937 56 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
erbb signaling pathway GO:0038127 9 0.012
myosin filament organization GO:0031033 138 0.012
regulation of cell division GO:0051302 142 0.012
digestive tract morphogenesis GO:0048546 76 0.012
regulation of protein metabolic process GO:0051246 81 0.011
catabolic process GO:0009056 318 0.011
negative regulation of multicellular organismal process GO:0051241 236 0.011
oocyte differentiation GO:0009994 45 0.011
regulation of cellular catabolic process GO:0031329 51 0.011
ribonucleotide catabolic process GO:0009261 75 0.011
cytoskeleton dependent cytokinesis GO:0061640 35 0.011
transmembrane transport GO:0055085 110 0.011
Mouse
regulation of cellular localization GO:0060341 42 0.011
Fly
establishment of synaptic vesicle localization GO:0097480 21 0.011
Fly
positive regulation of developmental growth GO:0048639 354 0.011
regulation of multicellular organism growth GO:0040014 373 0.011
actin cytoskeleton reorganization GO:0031532 4 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.011
positive regulation of catalytic activity GO:0043085 59 0.011
positive regulation of nucleotide metabolic process GO:0045981 28 0.011
positive regulation of response to stimulus GO:0048584 55 0.011
spindle localization GO:0051653 51 0.011
phosphorylation GO:0016310 116 0.011
Fly
macromolecular complex subunit organization GO:0043933 320 0.011
regulation of reproductive process GO:2000241 66 0.011
regulation of transcription dna templated GO:0006355 164 0.010
Mouse
regulation of ras protein signal transduction GO:0046578 41 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
Fly
cognition GO:0050890 27 0.010
Fly
positive regulation of secretion GO:0051047 17 0.010
intracellular transport GO:0046907 77 0.010
Rat
regulation of cell proliferation GO:0042127 105 0.010
Human

lin-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org