Caenorhabditis elegans

137 known processes

tlf-1 (CELE_F39H11.2)

Protein TLF-1

tlf-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
developmental process involved in reproduction GO:0003006 1165 0.349
Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.339
regulation of primary metabolic process GO:0080090 292 0.259
organ development GO:0048513 1102 0.246
cellular nitrogen compound biosynthetic process GO:0044271 192 0.236
nucleic acid templated transcription GO:0097659 169 0.215
cell division GO:0051301 262 0.215
embryo development GO:0009790 3052 0.213
locomotion GO:0040011 1634 0.208
meiotic cell cycle GO:0051321 335 0.204
cellular macromolecule biosynthetic process GO:0034645 247 0.183
multicellular organismal reproductive process GO:0048609 815 0.180
Mouse
macromolecule biosynthetic process GO:0009059 250 0.174
aromatic compound biosynthetic process GO:0019438 192 0.169
negative regulation of biological process GO:0048519 567 0.157
sexual reproduction GO:0019953 546 0.154
Mouse
gonad development GO:0008406 840 0.148
reproductive system development GO:0061458 850 0.144
receptor mediated endocytosis GO:0006898 715 0.140
Worm
cell cycle GO:0007049 526 0.137
genitalia development GO:0048806 741 0.137
signal transduction GO:0007165 317 0.136
regulation of multicellular organismal process GO:0051239 726 0.131
cell cycle process GO:0022402 482 0.126
single organism reproductive process GO:0044702 1196 0.124
Mouse
organic cyclic compound biosynthetic process GO:1901362 195 0.120
post embryonic development GO:0009791 2152 0.120
regulation of cellular metabolic process GO:0031323 305 0.120
organelle organization GO:0006996 783 0.116
Mouse
multicellular organism reproduction GO:0032504 819 0.116
Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.111
regulation of gene expression GO:0010468 366 0.107
macromolecule localization GO:0033036 771 0.107
organic substance biosynthetic process GO:1901576 323 0.106
regulation of macromolecule metabolic process GO:0060255 421 0.105
growth GO:0040007 562 0.103
hermaphrodite genitalia development GO:0040035 734 0.101
negative regulation of metabolic process GO:0009892 240 0.100
regulation of metabolic process GO:0019222 478 0.099
multi organism reproductive process GO:0044703 867 0.099
Mouse
female gamete generation GO:0007292 254 0.091
protein metabolic process GO:0019538 422 0.090
body morphogenesis GO:0010171 620 0.088
cell surface receptor signaling pathway GO:0007166 149 0.087
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.086
regulation of cell division GO:0051302 142 0.083
regulation of developmental process GO:0050793 684 0.083
single organism signaling GO:0044700 401 0.081
apoptotic process GO:0006915 478 0.078
gene expression GO:0010467 412 0.078
sex differentiation GO:0007548 909 0.078
regulation of growth GO:0040008 409 0.076
multicellular organism growth GO:0035264 385 0.076
development of primary sexual characteristics GO:0045137 840 0.076
rna metabolic process GO:0016070 228 0.072
reproductive structure development GO:0048608 850 0.069
muscle cell differentiation GO:0042692 171 0.069
multi organism reproductive behavior GO:0044705 387 0.069
positive regulation of developmental process GO:0051094 408 0.069
post embryonic organ development GO:0048569 336 0.069
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.068
Mouse
gamete generation GO:0007276 461 0.066
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.066
cellular component morphogenesis GO:0032989 318 0.066
Mouse
meiotic nuclear division GO:0007126 300 0.066
protein complex subunit organization GO:0071822 280 0.066
regulation of cell cycle process GO:0010564 145 0.066
macromolecular complex subunit organization GO:0043933 320 0.065
protein localization GO:0008104 205 0.063
nucleic acid metabolic process GO:0090304 299 0.062
nucleobase containing compound metabolic process GO:0006139 406 0.061
cellular component movement GO:0006928 388 0.061
multi multicellular organism process GO:0044706 390 0.061
aging GO:0007568 812 0.061
regulation of rna metabolic process GO:0051252 173 0.061
oogenesis GO:0048477 229 0.060
nucleobase containing compound biosynthetic process GO:0034654 184 0.059
vulval development GO:0040025 333 0.058
maintenance of location GO:0051235 580 0.057
multi organism behavior GO:0051705 389 0.057
positive regulation of cellular process GO:0048522 332 0.056
determination of adult lifespan GO:0008340 812 0.056
organelle fission GO:0048285 363 0.055
response to external stimulus GO:0009605 289 0.054
germ cell development GO:0007281 351 0.054
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.054
Mouse
programmed cell death GO:0012501 500 0.053
regulation of biological quality GO:0065008 741 0.052
regulation of cellular component organization GO:0051128 248 0.052
regulation of cellular biosynthetic process GO:0031326 189 0.052
cellular component biogenesis GO:0044085 297 0.051
Mouse
regulation of signal transduction GO:0009966 135 0.051
biosynthetic process GO:0009058 323 0.050
establishment of localization GO:0051234 1171 0.050
Worm
lipid storage GO:0019915 565 0.050
cellular component assembly GO:0022607 293 0.050
Mouse
regulation of biosynthetic process GO:0009889 189 0.049
negative regulation of cellular process GO:0048523 239 0.049
regulation of protein metabolic process GO:0051246 81 0.048
regulation of signaling GO:0023051 172 0.048
regulation of multicellular organismal development GO:2000026 317 0.047
cell fate commitment GO:0045165 139 0.047
cellular protein metabolic process GO:0044267 279 0.047
generation of neurons GO:0048699 235 0.047
lipid localization GO:0010876 573 0.046
cell morphogenesis GO:0000902 163 0.046
positive regulation of growth GO:0045927 369 0.045
response to wounding GO:0009611 4 0.044
negative regulation of multicellular organismal process GO:0051241 236 0.044
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.044
cellular protein modification process GO:0006464 207 0.043
negative regulation of developmental process GO:0051093 227 0.043
rna biosynthetic process GO:0032774 169 0.043
positive regulation of vulval development GO:0040026 52 0.041
transport GO:0006810 1093 0.041
Worm
negative regulation of cellular metabolic process GO:0031324 95 0.041
regulation of nucleic acid templated transcription GO:1903506 165 0.041
oviposition GO:0018991 364 0.040
regulation of multicellular organism growth GO:0040014 373 0.040
reproductive behavior GO:0019098 387 0.040
negative regulation of post embryonic development GO:0048581 208 0.040
regulation of organ morphogenesis GO:2000027 4 0.039
macromolecule catabolic process GO:0009057 202 0.039
endocytosis GO:0006897 819 0.038
Worm
protein complex assembly GO:0006461 186 0.037
regulation of cellular protein metabolic process GO:0032268 75 0.037
striated muscle cell differentiation GO:0051146 158 0.037
cell death GO:0008219 547 0.037
regulation of phosphorus metabolic process GO:0051174 81 0.036
behavior GO:0007610 527 0.036
vesicle mediated transport GO:0016192 852 0.036
Worm
negative regulation of gene expression GO:0010629 217 0.035
regulation of developmental growth GO:0048638 389 0.035
regulation of nematode larval development GO:0061062 260 0.034
cellular catabolic process GO:0044248 199 0.034
cell development GO:0048468 696 0.034
Mouse
cell motility GO:0048870 313 0.034
negative regulation of vulval development GO:0040027 206 0.034
death GO:0016265 547 0.033
intracellular signal transduction GO:0035556 96 0.033
protein complex biogenesis GO:0070271 186 0.033
cell migration GO:0016477 306 0.033
regulation of nitrogen compound metabolic process GO:0051171 222 0.033
developmental growth GO:0048589 412 0.032
myofibril assembly GO:0030239 154 0.032
negative regulation of biosynthetic process GO:0009890 65 0.032
negative regulation of macromolecule metabolic process GO:0010605 229 0.031
catabolic process GO:0009056 318 0.031
localization of cell GO:0051674 313 0.031
positive regulation of neuron projection development GO:0010976 4 0.031
posttranscriptional regulation of gene expression GO:0010608 166 0.031
cell proliferation GO:0008283 116 0.031
epithelial cell proliferation GO:0050673 1 0.031
cellular component assembly involved in morphogenesis GO:0010927 183 0.031
Mouse
tube morphogenesis GO:0035239 79 0.030
establishment of localization in cell GO:0051649 318 0.030
cellular localization GO:0051641 360 0.029
regulation of macromolecule biosynthetic process GO:0010556 189 0.029
regulation of response to wounding GO:1903034 1 0.029
striated muscle cell development GO:0055002 157 0.028
positive regulation of neurogenesis GO:0050769 4 0.028
head development GO:0060322 1 0.028
regulation of response to stimulus GO:0048583 243 0.028
positive regulation of cellular metabolic process GO:0031325 178 0.028
signaling GO:0023052 401 0.027
regulation of cell proliferation GO:0042127 105 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.027
regulation of localization GO:0032879 194 0.027
signal transduction by phosphorylation GO:0023014 31 0.027
muscle cell development GO:0055001 158 0.027
regulation of transcription dna templated GO:0006355 164 0.026
single organism transport GO:0044765 447 0.026
organ morphogenesis GO:0009887 67 0.026
regulation of vulval development GO:0040028 248 0.026
regulation of apoptotic signaling pathway GO:2001233 1 0.026
positive regulation of signaling GO:0023056 66 0.025
neuron differentiation GO:0030182 217 0.025
regulation of meiosis GO:0040020 94 0.025
multicellular organismal aging GO:0010259 812 0.025
transcription from rna polymerase ii promoter GO:0006366 149 0.025
negative regulation of nematode larval development GO:0061064 208 0.025
myosin filament assembly GO:0031034 138 0.025
multicellular organismal reproductive behavior GO:0033057 384 0.024
regulation of cell communication GO:0010646 176 0.024
macromolecular complex assembly GO:0065003 193 0.023
muscle structure development GO:0061061 191 0.023
protein oligomerization GO:0051259 4 0.023
response to external biotic stimulus GO:0043207 101 0.023
chromosome segregation GO:0007059 180 0.023
regulation of organelle organization GO:0033043 164 0.023
tube development GO:0035295 126 0.023
actin filament based process GO:0030029 191 0.022
cellular macromolecular complex assembly GO:0034622 184 0.022
positive regulation of multicellular organism growth GO:0040018 352 0.022
regulation of rna biosynthetic process GO:2001141 165 0.022
regulation of cell differentiation GO:0045595 81 0.022
organelle assembly GO:0070925 214 0.021
Mouse
microtubule based process GO:0007017 182 0.021
regulation of post embryonic development GO:0048580 260 0.021
cytoskeleton organization GO:0007010 339 0.020
nervous system development GO:0007399 253 0.020
organic substance catabolic process GO:1901575 294 0.020
striated muscle myosin thick filament assembly GO:0071688 138 0.020
notch signaling pathway GO:0007219 22 0.020
positive regulation of gene expression GO:0010628 112 0.019
positive regulation of developmental growth GO:0048639 354 0.019
protein phosphorylation GO:0006468 85 0.019
actin cytoskeleton organization GO:0030036 184 0.019
cellular response to chemical stimulus GO:0070887 129 0.019
meiotic cell cycle process GO:1903046 170 0.019
response to abiotic stimulus GO:0009628 152 0.019
cellular response to dna damage stimulus GO:0006974 41 0.019
regulation of mapk cascade GO:0043408 23 0.019
regulation of meiotic cell cycle GO:0051445 136 0.019
cuticle development GO:0042335 100 0.018
regulation of cell fate specification GO:0042659 22 0.018
protein transport GO:0015031 45 0.018
macromolecule modification GO:0043412 218 0.018
organophosphate catabolic process GO:0046434 81 0.018
regulation of catalytic activity GO:0050790 78 0.017
asymmetric cell division GO:0008356 36 0.017
single organism catabolic process GO:0044712 129 0.017
regulation of molecular function GO:0065009 89 0.017
organic substance transport GO:0071702 113 0.017
phosphorus metabolic process GO:0006793 232 0.017
regulation of phosphate metabolic process GO:0019220 81 0.017
cellular response to abiotic stimulus GO:0071214 4 0.017
myosin filament organization GO:0031033 138 0.017
negative regulation of signaling GO:0023057 61 0.017
regulation of cell cycle GO:0051726 194 0.017
immune response regulating signaling pathway GO:0002764 1 0.017
spermatogenesis GO:0007283 41 0.017
Mouse
sensory organ morphogenesis GO:0090596 2 0.017
inductive cell migration GO:0040039 145 0.017
response to chemical GO:0042221 356 0.017
regulation of nuclear division GO:0051783 115 0.016
transcription dna templated GO:0006351 168 0.016
regulation of locomotion GO:0040012 161 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
chromatin remodeling GO:0006338 2 0.016
single organism organelle organization GO:1902589 501 0.015
Mouse
cell type specific apoptotic process GO:0097285 4 0.015
heterocycle biosynthetic process GO:0018130 187 0.015
defense response GO:0006952 296 0.015
negative regulation of signal transduction GO:0009968 60 0.015
cellular response to stress GO:0033554 162 0.015
regulation of protein stability GO:0031647 3 0.015
negative regulation of response to stimulus GO:0048585 73 0.015
negative regulation of cell communication GO:0010648 61 0.015
response to biotic stimulus GO:0009607 101 0.014
protein modification process GO:0036211 207 0.014
rho protein signal transduction GO:0007266 2 0.014
regulation of cell motility GO:2000145 57 0.014
oocyte differentiation GO:0009994 45 0.014
actomyosin structure organization GO:0031032 154 0.014
protein catabolic process GO:0030163 162 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
positive regulation of neuron differentiation GO:0045666 4 0.013
molting cycle GO:0042303 281 0.013
proteolysis GO:0006508 61 0.013
establishment of organelle localization GO:0051656 123 0.013
regulation of transport GO:0051049 91 0.013
small gtpase mediated signal transduction GO:0007264 32 0.013
secretion GO:0046903 147 0.013
positive regulation of macromolecule metabolic process GO:0010604 149 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.013
response to bacterium GO:0009617 86 0.013
digestive tract morphogenesis GO:0048546 76 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.012
membrane organization GO:0061024 135 0.012
positive regulation of metabolic process GO:0009893 187 0.012
single organism intracellular transport GO:1902582 70 0.012
phosphorylation GO:0016310 116 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
regulation of catabolic process GO:0009894 57 0.012
embryonic morphogenesis GO:0048598 152 0.012
regulation of epithelial cell proliferation GO:0050678 1 0.012
negative regulation of nucleic acid templated transcription GO:1903507 53 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
establishment or maintenance of cell polarity GO:0007163 63 0.011
response to other organism GO:0051707 101 0.011
regulation of protein localization GO:0032880 50 0.011
regulation of ras protein signal transduction GO:0046578 41 0.011
regulation of transferase activity GO:0051338 31 0.011
cellular biosynthetic process GO:0044249 315 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
organonitrogen compound metabolic process GO:1901564 151 0.011
Mouse
rna interference GO:0016246 137 0.011
response to endoplasmic reticulum stress GO:0034976 71 0.011
cell projection organization GO:0030030 231 0.011
mitotic cell cycle process GO:1903047 194 0.011
positive regulation of response to stimulus GO:0048584 55 0.011
defense response to bacterium GO:0042742 86 0.011
organophosphate metabolic process GO:0019637 125 0.010
Mouse
regulation of intracellular signal transduction GO:1902531 77 0.010
secretion by cell GO:0032940 138 0.010
purine ribonucleotide catabolic process GO:0009154 75 0.010
cellular amino acid metabolic process GO:0006520 15 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
cell morphogenesis involved in differentiation GO:0000904 112 0.010
system process GO:0003008 136 0.010
pigmentation GO:0043473 2 0.010
positive regulation of catalytic activity GO:0043085 59 0.010
regulation of protein modification process GO:0031399 46 0.010
adult behavior GO:0030534 3 0.010
regulation of cytoplasmic transport GO:1903649 3 0.010
positive regulation of phosphate metabolic process GO:0045937 56 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
cellular protein complex assembly GO:0043623 178 0.010
cellular macromolecule localization GO:0070727 75 0.010

tlf-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.013