Caenorhabditis elegans

220 known processes

pop-1 (CELE_W10C8.2)

Protein POP-1

pop-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.998
cell fate commitment GO:0045165 139 0.997
gastrulation GO:0007369 58 0.974
digestive tract morphogenesis GO:0048546 76 0.903
tube morphogenesis GO:0035239 79 0.849
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.842
mesodermal cell differentiation GO:0048333 15 0.825
embryo development GO:0009790 3052 0.805
regulation of vulval development GO:0040028 248 0.800
mesoderm development GO:0007498 27 0.770
proximal distal axis specification GO:0009946 6 0.757
neuron projection guidance GO:0097485 82 0.742
tissue development GO:0009888 112 0.732
positive regulation of cellular biosynthetic process GO:0031328 109 0.727
organ development GO:0048513 1102 0.720
positive regulation of nematode larval development GO:0061063 54 0.712
proximal distal pattern formation GO:0009954 6 0.660
positive regulation of transcription dna templated GO:0045893 102 0.660
cellular nitrogen compound biosynthetic process GO:0044271 192 0.655
digestive system development GO:0055123 122 0.654
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.622
digestive tract development GO:0048565 122 0.610
post embryonic organ development GO:0048569 336 0.610
specification of axis polarity GO:0065001 13 0.594
axonogenesis GO:0007409 102 0.591
mesodermal cell fate specification GO:0007501 13 0.590
embryo development ending in birth or egg hatching GO:0009792 2992 0.584
positive regulation of metabolic process GO:0009893 187 0.580
positive regulation of cellular process GO:0048522 332 0.575
cell projection organization GO:0030030 231 0.569
positive regulation of rna metabolic process GO:0051254 103 0.569
axon guidance GO:0007411 82 0.564
gonad development GO:0008406 840 0.561
microtubule based process GO:0007017 182 0.550
post embryonic development GO:0009791 2152 0.548
nucleic acid metabolic process GO:0090304 299 0.539
multicellular organism reproduction GO:0032504 819 0.518
regulation of post embryonic development GO:0048580 260 0.515
heterocycle biosynthetic process GO:0018130 187 0.514
organic cyclic compound biosynthetic process GO:1901362 195 0.512
developmental process involved in reproduction GO:0003006 1165 0.490
neurogenesis GO:0022008 236 0.489
regulation of nematode larval development GO:0061062 260 0.486
positive regulation of nucleic acid templated transcription GO:1903508 102 0.484
positive regulation of rna biosynthetic process GO:1902680 102 0.483
vulval development GO:0040025 333 0.470
regulation of primary metabolic process GO:0080090 292 0.463
rna metabolic process GO:0016070 228 0.462
hermaphrodite genitalia development GO:0040035 734 0.459
single organism organelle organization GO:1902589 501 0.459
locomotion GO:0040011 1634 0.456
Human Zebrafish Mouse
reproductive structure development GO:0048608 850 0.446
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.445
regulation of metabolic process GO:0019222 478 0.445
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.443
neuron projection morphogenesis GO:0048812 114 0.442
rna biosynthetic process GO:0032774 169 0.440
embryonic morphogenesis GO:0048598 152 0.438
endodermal cell differentiation GO:0035987 18 0.437
multicellular organismal reproductive process GO:0048609 815 0.432
cell projection morphogenesis GO:0048858 148 0.429
gene expression GO:0010467 412 0.428
regulation of macromolecule metabolic process GO:0060255 421 0.426
transcription dna templated GO:0006351 168 0.424
taxis GO:0042330 128 0.423
Human
tube development GO:0035295 126 0.419
axon development GO:0061564 163 0.417
sexual reproduction GO:0019953 546 0.416
single organism reproductive process GO:0044702 1196 0.414
regulation of transcription dna templated GO:0006355 164 0.414
aromatic compound biosynthetic process GO:0019438 192 0.412
spindle organization GO:0007051 92 0.409
polarity specification of proximal distal axis GO:0010085 6 0.405
transcription from rna polymerase ii promoter GO:0006366 149 0.403
neuron projection development GO:0031175 187 0.401
single organism signaling GO:0044700 401 0.401
Human Zebrafish Mouse Fly
genitalia development GO:0048806 741 0.396
positive regulation of cellular metabolic process GO:0031325 178 0.389
cell migration GO:0016477 306 0.388
Human Zebrafish Mouse
gamete generation GO:0007276 461 0.387
anatomical structure formation involved in morphogenesis GO:0048646 250 0.378
chemotaxis GO:0006935 120 0.369
Human
regulation of rna biosynthetic process GO:2001141 165 0.369
multi organism reproductive process GO:0044703 867 0.368
regulation of nucleic acid templated transcription GO:1903506 165 0.366
organelle organization GO:0006996 783 0.365
nucleobase containing compound metabolic process GO:0006139 406 0.364
regulation of rna metabolic process GO:0051252 173 0.363
positive regulation of gene expression GO:0010628 112 0.351
sex differentiation GO:0007548 909 0.350
regulation of nitrogen compound metabolic process GO:0051171 222 0.346
mitotic cell cycle process GO:1903047 194 0.337
regulation of gene expression GO:0010468 366 0.336
endoderm development GO:0007492 20 0.332
positive regulation of vulval development GO:0040026 52 0.328
regulation of signaling GO:0023051 172 0.326
Human Zebrafish Mouse Fly
negative regulation of vulval development GO:0040027 206 0.322
localization of cell GO:0051674 313 0.315
Human Zebrafish Mouse
cellular component movement GO:0006928 388 0.313
Human Zebrafish Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.312
neuron development GO:0048666 199 0.308
pharynx development GO:0060465 51 0.302
generation of neurons GO:0048699 235 0.295
mitotic spindle organization GO:0007052 81 0.294
cell development GO:0048468 696 0.292
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.290
oviposition GO:0018991 364 0.289
positive regulation of macromolecule metabolic process GO:0010604 149 0.280
negative regulation of nematode larval development GO:0061064 208 0.278
regulation of developmental process GO:0050793 684 0.277
female gamete generation GO:0007292 254 0.274
negative regulation of post embryonic development GO:0048581 208 0.272
regulation of cell division GO:0051302 142 0.272
multicellular organismal aging GO:0010259 812 0.268
germ cell development GO:0007281 351 0.266
multi multicellular organism process GO:0044706 390 0.266
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.257
determination of adult lifespan GO:0008340 812 0.251
receptor mediated endocytosis GO:0006898 715 0.249
vesicle mediated transport GO:0016192 852 0.247
multicellular organismal reproductive behavior GO:0033057 384 0.241
regulation of macromolecule biosynthetic process GO:0010556 189 0.237
nervous system development GO:0007399 253 0.235
nucleic acid templated transcription GO:0097659 169 0.235
regulation of cellular component organization GO:0051128 248 0.234
Human
development of primary sexual characteristics GO:0045137 840 0.233
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.226
regulation of multicellular organismal development GO:2000026 317 0.224
development of primary male sexual characteristics GO:0046546 4 0.223
cell morphogenesis involved in differentiation GO:0000904 112 0.219
Human Mouse
negative regulation of transcription dna templated GO:0045892 53 0.215
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.210
wnt signaling pathway GO:0016055 27 0.209
Human Zebrafish Mouse Fly
regulation of cellular biosynthetic process GO:0031326 189 0.208
nucleobase containing compound biosynthetic process GO:0034654 184 0.207
negative regulation of cellular metabolic process GO:0031324 95 0.203
aging GO:0007568 812 0.203
reproductive behavior GO:0019098 387 0.202
head development GO:0060322 1 0.201
Zebrafish Mouse
positive regulation of post embryonic development GO:0048582 54 0.201
regulation of cellular metabolic process GO:0031323 305 0.198
reproductive system development GO:0061458 850 0.198
regulation of organelle organization GO:0033043 164 0.196
regulation of cell fate specification GO:0042659 22 0.194
multi organism reproductive behavior GO:0044705 387 0.193
regulation of multicellular organismal process GO:0051239 726 0.192
cell part morphogenesis GO:0032990 152 0.191
positive regulation of biosynthetic process GO:0009891 109 0.190
endocytosis GO:0006897 819 0.186
male sex differentiation GO:0046661 86 0.185
tissue morphogenesis GO:0048729 65 0.183
regulation of cell fate commitment GO:0010453 22 0.180
cell morphogenesis GO:0000902 163 0.180
Human Mouse
regulation of biosynthetic process GO:0009889 189 0.178
biosynthetic process GO:0009058 323 0.178
response to external stimulus GO:0009605 289 0.175
Human Mouse
behavior GO:0007610 527 0.174
cell motility GO:0048870 313 0.170
Human Zebrafish Mouse
multi organism behavior GO:0051705 389 0.169
death GO:0016265 547 0.168
positive regulation of stem cell differentiation GO:2000738 1 0.167
Human
body morphogenesis GO:0010171 620 0.166
Zebrafish Mouse
cell cycle GO:0007049 526 0.166
signaling GO:0023052 401 0.163
Human Zebrafish Mouse Fly
muscle cell differentiation GO:0042692 171 0.159
Human Zebrafish Mouse
negative regulation of metabolic process GO:0009892 240 0.157
meiotic cell cycle GO:0051321 335 0.154
negative regulation of developmental process GO:0051093 227 0.153
positive regulation of growth GO:0045927 369 0.152
Human
negative regulation of biological process GO:0048519 567 0.152
neuron differentiation GO:0030182 217 0.151
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.145
pattern specification process GO:0007389 59 0.144
positive regulation of cell communication GO:0010647 69 0.144
Human Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.141
response to chemical GO:0042221 356 0.140
Human Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.138
Human Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.138
negative regulation of cellular biosynthetic process GO:0031327 65 0.137
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.137
Human
cellular component morphogenesis GO:0032989 318 0.133
Human Mouse
regulation of biological quality GO:0065008 741 0.132
Human Zebrafish Mouse
nematode male tail tip morphogenesis GO:0045138 77 0.131
signal transduction GO:0007165 317 0.130
Human Zebrafish Mouse Fly
negative regulation of rna biosynthetic process GO:1902679 53 0.129
macromolecule biosynthetic process GO:0009059 250 0.127
regulation of meiosis GO:0040020 94 0.127
cell surface receptor signaling pathway GO:0007166 149 0.125
Human Zebrafish Mouse Fly
cell death GO:0008219 547 0.124
oogenesis GO:0048477 229 0.120
transport GO:0006810 1093 0.117
regionalization GO:0003002 31 0.117
protein localization GO:0008104 205 0.116
Human Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.115
Mouse
cellular biosynthetic process GO:0044249 315 0.115
negative regulation of gene expression GO:0010629 217 0.114
homeostatic process GO:0042592 51 0.113
Human Zebrafish Mouse
organic substance biosynthetic process GO:1901576 323 0.112
cellular component biogenesis GO:0044085 297 0.112
macromolecule localization GO:0033036 771 0.110
Human Mouse
positive regulation of signaling GO:0023056 66 0.109
Human Mouse
cytoskeleton organization GO:0007010 339 0.109
mesoderm morphogenesis GO:0048332 24 0.105
regulation of cytoplasmic transport GO:1903649 3 0.104
Human
canonical wnt signaling pathway GO:0060070 3 0.103
Human Zebrafish Mouse
cellular component assembly GO:0022607 293 0.101
developmental growth involved in morphogenesis GO:0060560 37 0.100
molting cycle GO:0042303 281 0.100
dendrite development GO:0016358 42 0.100
epithelial tube morphogenesis GO:0060562 1 0.099
Mouse
cilium morphogenesis GO:0060271 33 0.098
negative regulation of macromolecule metabolic process GO:0010605 229 0.095
inductive cell migration GO:0040039 145 0.093
embryonic pattern specification GO:0009880 21 0.092
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.092
regulation of cell differentiation GO:0045595 81 0.092
cell cycle process GO:0022402 482 0.088
negative regulation of cellular process GO:0048523 239 0.088
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.088
regulation of cell cycle GO:0051726 194 0.088
Human
regulation of organ morphogenesis GO:2000027 4 0.087
muscle structure development GO:0061061 191 0.085
protein complex subunit organization GO:0071822 280 0.085
sensory organ morphogenesis GO:0090596 2 0.084
Zebrafish
regulation of cell cycle process GO:0010564 145 0.083
Human
organic substance catabolic process GO:1901575 294 0.081
meiotic nuclear division GO:0007126 300 0.080
establishment of localization GO:0051234 1171 0.080
programmed cell death GO:0012501 500 0.079
regulation of cell communication GO:0010646 176 0.078
Human Zebrafish Mouse Fly
positive regulation of developmental growth GO:0048639 354 0.078
organelle assembly GO:0070925 214 0.075
maintenance of location GO:0051235 580 0.075
intracellular receptor signaling pathway GO:0030522 2 0.073
macromolecular complex subunit organization GO:0043933 320 0.072
regulation of locomotion GO:0040012 161 0.072
Human Zebrafish
synaptic transmission GO:0007268 106 0.071
regulation of nucleocytoplasmic transport GO:0046822 3 0.071
Human
response to wounding GO:0009611 4 0.070
Zebrafish
posttranscriptional regulation of gene expression GO:0010608 166 0.070
developmental growth GO:0048589 412 0.069
Zebrafish Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.069
lipid metabolic process GO:0006629 77 0.069
Zebrafish Mouse
regulation of stem cell differentiation GO:2000736 1 0.069
Human Mouse
positive regulation of developmental process GO:0051094 408 0.069
cellular response to chemical stimulus GO:0070887 129 0.068
Human Mouse
cellular localization GO:0051641 360 0.067
Human Mouse
positive regulation of neurogenesis GO:0050769 4 0.066
Zebrafish
single organism localization GO:1902578 518 0.066
response to organic substance GO:0010033 131 0.066
Human Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.065
Human
cellular macromolecule biosynthetic process GO:0034645 247 0.065
regulation of neuron differentiation GO:0045664 40 0.064
lipid storage GO:0019915 565 0.064
regulation of epithelial cell proliferation GO:0050678 1 0.064
Mouse
regulation of growth GO:0040008 409 0.063
Human Mouse
spindle localization GO:0051653 51 0.063
macromolecule modification GO:0043412 218 0.063
Human
macromolecular complex assembly GO:0065003 193 0.062
negative regulation of biosynthetic process GO:0009890 65 0.061
regulation of meiotic cell cycle GO:0051445 136 0.061
regulation of response to stimulus GO:0048583 243 0.061
Human Zebrafish Mouse Fly
muscle cell development GO:0055001 158 0.061
Zebrafish
response to fibroblast growth factor GO:0071774 5 0.061
Mouse
negative regulation of neurogenesis GO:0050768 4 0.060
striated muscle cell development GO:0055002 157 0.060
Zebrafish
response to abiotic stimulus GO:0009628 152 0.059
positive regulation of multicellular organism growth GO:0040018 352 0.059
asymmetric cell division GO:0008356 36 0.059
regulation of multicellular organism growth GO:0040014 373 0.058
catabolic process GO:0009056 318 0.057
male anatomical structure morphogenesis GO:0090598 78 0.056
establishment of spindle localization GO:0051293 51 0.056
regeneration GO:0031099 4 0.054
Zebrafish
regulation of cell migration GO:0030334 55 0.054
Human Zebrafish
lipid localization GO:0010876 573 0.054
negative regulation of wnt signaling pathway GO:0030178 6 0.053
Human Zebrafish
neuron projection extension GO:1990138 37 0.053
neural precursor cell proliferation GO:0061351 9 0.052
Zebrafish Mouse
intracellular transport GO:0046907 77 0.052
Human Mouse
positive regulation of cell migration GO:0030335 3 0.052
Human
cellular protein metabolic process GO:0044267 279 0.051
Human
protein metabolic process GO:0019538 422 0.050
Human Mouse
muscle organ development GO:0007517 26 0.050
memory GO:0007613 3 0.050
skeletal muscle organ development GO:0060538 3 0.049
Mouse
epithelium development GO:0060429 68 0.049
Zebrafish Mouse
cell projection assembly GO:0030031 35 0.049
regulation of gene expression epigenetic GO:0040029 163 0.049
regulation of cell proliferation GO:0042127 105 0.049
Human Zebrafish Mouse Fly
regulation of catabolic process GO:0009894 57 0.049
phosphorylation GO:0016310 116 0.048
cell cell signaling GO:0007267 118 0.048
Human Mouse
positive regulation of locomotion GO:0040017 42 0.048
Human
positive regulation of signal transduction GO:0009967 40 0.048
Human
tube formation GO:0035148 2 0.047
organ morphogenesis GO:0009887 67 0.047
Zebrafish Mouse Fly
regulation of developmental growth GO:0048638 389 0.047
Mouse
regulation of intracellular signal transduction GO:1902531 77 0.046
Human
cellular response to organic substance GO:0071310 119 0.046
Human Mouse
protein modification process GO:0036211 207 0.046
Human
single organism transport GO:0044765 447 0.045
oocyte development GO:0048599 44 0.045
establishment of mitotic spindle localization GO:0040001 41 0.045
oocyte differentiation GO:0009994 45 0.045
neuron projection extension involved in neuron projection guidance GO:1902284 13 0.044
cellular macromolecular complex assembly GO:0034622 184 0.044
cellular component assembly involved in morphogenesis GO:0010927 183 0.044
positive regulation of catabolic process GO:0009896 38 0.044
membrane organization GO:0061024 135 0.043
protein catabolic process GO:0030163 162 0.043
muscle tissue development GO:0060537 1 0.043
Mouse
organelle fission GO:0048285 363 0.042
axis specification GO:0009798 23 0.042
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.042
phosphorus metabolic process GO:0006793 232 0.042
ras protein signal transduction GO:0007265 31 0.042
macromolecule catabolic process GO:0009057 202 0.041
cell division GO:0051301 262 0.041
regulation of nuclear division GO:0051783 115 0.041
regulation of neurogenesis GO:0050767 40 0.041
Zebrafish Mouse
regulation of cell development GO:0060284 49 0.040
Human Zebrafish Mouse
actin filament based process GO:0030029 191 0.039
growth GO:0040007 562 0.039
Human Zebrafish Mouse
anatomical structure homeostasis GO:0060249 11 0.039
Zebrafish
neuron fate specification GO:0048665 8 0.039
positive regulation of intracellular transport GO:0032388 2 0.039
Human
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 5 0.038
embryonic body morphogenesis GO:0010172 49 0.038
regulation of axon extension GO:0030516 20 0.038
establishment of localization in cell GO:0051649 318 0.037
Human Mouse
establishment of cell polarity GO:0030010 46 0.037
axon extension involved in axon guidance GO:0048846 13 0.037
defense response GO:0006952 296 0.037
cellular response to abiotic stimulus GO:0071214 4 0.037
epithelial cell proliferation GO:0050673 1 0.036
Mouse
positive regulation of response to stimulus GO:0048584 55 0.036
Human
regulation of neuron projection development GO:0010975 31 0.036
nonmotile primary cilium assembly GO:0035058 18 0.035
positive regulation of cell projection organization GO:0031346 4 0.035
cellular protein complex assembly GO:0043623 178 0.035
maintenance of protein location GO:0045185 15 0.034
apoptotic process GO:0006915 478 0.034
adult behavior GO:0030534 3 0.034
chromosome organization GO:0051276 104 0.034
Human
system process GO:0003008 136 0.034
neuron recognition GO:0008038 83 0.034
bmp signaling pathway GO:0030509 3 0.034
Mouse
protein complex assembly GO:0006461 186 0.034
cell recognition GO:0008037 85 0.034
phosphate containing compound metabolic process GO:0006796 232 0.034
organic cyclic compound catabolic process GO:1901361 119 0.034
mating GO:0007618 34 0.034
small molecule metabolic process GO:0044281 186 0.034
Human Zebrafish Mouse
ectoderm development GO:0007398 3 0.033
cell fate specification involved in pattern specification GO:0060573 4 0.033
cellular protein localization GO:0034613 75 0.033
Human Mouse
developmental induction GO:0031128 1 0.033
regulation of cellular protein metabolic process GO:0032268 75 0.033
Human
multicellular organism growth GO:0035264 385 0.032
Mouse
single organism behavior GO:0044708 83 0.032
regulation of anatomical structure morphogenesis GO:0022603 51 0.032
Human
positive regulation of neuron differentiation GO:0045666 4 0.032
posttranscriptional gene silencing GO:0016441 143 0.032
translation GO:0006412 37 0.032
regulation of reproductive process GO:2000241 66 0.031
adult locomotory behavior GO:0008344 1 0.031
regulation of wnt signaling pathway GO:0030111 9 0.031
Human Zebrafish Mouse Fly
covalent chromatin modification GO:0016569 30 0.030
Human
regulation of filopodium assembly GO:0051489 2 0.030
striated muscle cell differentiation GO:0051146 158 0.030
Zebrafish
rho protein signal transduction GO:0007266 2 0.030
neuron fate commitment GO:0048663 8 0.030
cellular catabolic process GO:0044248 199 0.030
single organism cellular localization GO:1902580 72 0.030
Mouse
cuticle development GO:0042335 100 0.029
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 2 0.029
regulation of synapse assembly GO:0051963 2 0.029
heterocycle catabolic process GO:0046700 119 0.029
anterior posterior pattern specification GO:0009952 27 0.029
Zebrafish Mouse
regulation of cell morphogenesis GO:0022604 40 0.029
Human
cell proliferation GO:0008283 116 0.029
Human Zebrafish Mouse Fly
stem cell differentiation GO:0048863 7 0.029
Human Zebrafish Mouse
establishment or maintenance of cell polarity GO:0007163 63 0.029
motor neuron axon guidance GO:0008045 13 0.029
mapk cascade GO:0000165 31 0.029
organism emergence from protective structure GO:0071684 48 0.028
positive regulation of neuron projection development GO:0010976 4 0.028
myofibril assembly GO:0030239 154 0.028
regulation of axonogenesis GO:0050770 24 0.028
regulation of signal transduction GO:0009966 135 0.028
Human Zebrafish Mouse Fly
cellular response to growth factor stimulus GO:0071363 18 0.028
Mouse
protein localization to organelle GO:0033365 37 0.028
Mouse
positive regulation of embryonic development GO:0040019 3 0.028
positive regulation of cellular catabolic process GO:0031331 35 0.028
negative regulation of rna metabolic process GO:0051253 53 0.028
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacterium GO:1902097 4 0.028
regulation of mitotic cell cycle GO:0007346 76 0.027
regulation of bmp signaling pathway GO:0030510 3 0.027
Mouse
regulation of protein import into nucleus GO:0042306 3 0.027
regulation of transport GO:0051049 91 0.027
carboxylic acid metabolic process GO:0019752 34 0.027
Zebrafish
oocyte axis specification GO:0007309 2 0.027
aromatic compound catabolic process GO:0019439 116 0.026
locomotory behavior GO:0007626 40 0.026
regulation of ras protein signal transduction GO:0046578 41 0.026
nucleobase containing compound catabolic process GO:0034655 114 0.026
regulation of localization GO:0032879 194 0.026
dna metabolic process GO:0006259 74 0.026
Human Mouse
apoptotic cell clearance GO:0043277 111 0.025
positive regulation of stress activated mapk cascade GO:0032874 3 0.025
regulation of apoptotic signaling pathway GO:2001233 1 0.025
Human
muscle organ morphogenesis GO:0048644 4 0.025
positive regulation of cell cycle GO:0045787 55 0.025
Human
rna interference GO:0016246 137 0.025
collagen and cuticulin based cuticle development GO:0040002 99 0.025
negative regulation of cellular protein metabolic process GO:0032269 27 0.024
Human
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.024
developmental cell growth GO:0048588 39 0.024
phagocytosis GO:0006909 115 0.024
protein complex biogenesis GO:0070271 186 0.024
secretion GO:0046903 147 0.024
organelle localization GO:0051640 127 0.024
Mouse
axon extension GO:0048675 37 0.024
oxoacid metabolic process GO:0043436 47 0.024
Human Zebrafish
meiotic cell cycle process GO:1903046 170 0.023
regulation of chromosome segregation GO:0051983 20 0.023
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.023
regulation of microtubule based process GO:0032886 21 0.023
male gonad development GO:0008584 4 0.023
organic acid metabolic process GO:0006082 47 0.023
Human Zebrafish
mating behavior GO:0007617 32 0.023
actin cytoskeleton organization GO:0030036 184 0.023
negative regulation of nucleic acid templated transcription GO:1903507 53 0.022
establishment of spindle orientation GO:0051294 34 0.022
dauer larval development GO:0040024 92 0.022
pigmentation GO:0043473 2 0.022
single organism intracellular transport GO:1902582 70 0.022
Human Mouse
epithelial cell morphogenesis GO:0003382 2 0.022
chromatin modification GO:0016568 32 0.022
Human
guanosine containing compound catabolic process GO:1901069 48 0.022
spermatogenesis GO:0007283 41 0.022
intracellular signal transduction GO:0035556 96 0.022
Human
microtubule polymerization or depolymerization GO:0031109 22 0.022
regulation of protein targeting GO:1903533 3 0.022
regulation of chromosome organization GO:0033044 20 0.021
positive regulation of protein transport GO:0051222 4 0.021
Human
hyperosmotic response GO:0006972 19 0.021
neuroblast fate determination GO:0007400 1 0.021
gene silencing GO:0016458 143 0.021
chromosome segregation GO:0007059 180 0.021
posttranscriptional gene silencing by rna GO:0035194 143 0.021
protein phosphorylation GO:0006468 85 0.021
small gtpase mediated signal transduction GO:0007264 32 0.021
actomyosin structure organization GO:0031032 154 0.021
regulation of lipid metabolic process GO:0019216 4 0.021
Zebrafish Mouse
response to external biotic stimulus GO:0043207 101 0.021
regulation of molecular function GO:0065009 89 0.020
Human
regulation of cellular component movement GO:0051270 62 0.020
Human Zebrafish
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.020
negative regulation of neuron differentiation GO:0045665 4 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.020
Mouse
oocyte construction GO:0007308 2 0.020
regulation of cellular catabolic process GO:0031329 51 0.020
detection of external stimulus GO:0009581 4 0.020
establishment of mitotic spindle orientation GO:0000132 28 0.020
male gamete generation GO:0048232 41 0.019
regulation of small gtpase mediated signal transduction GO:0051056 41 0.019
striated muscle myosin thick filament assembly GO:0071688 138 0.019
negative regulation of cell cycle GO:0045786 53 0.019
Human
regulation of protein metabolic process GO:0051246 81 0.019
Human
purine containing compound catabolic process GO:0072523 75 0.019
synaptic target recognition GO:0008039 3 0.019
cellular protein catabolic process GO:0044257 37 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
regulation of canonical wnt signaling pathway GO:0060828 1 0.019
Human
long term memory GO:0007616 2 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.018
Zebrafish Mouse
myosin filament organization GO:0031033 138 0.018
myosin filament assembly GO:0031034 138 0.018
cell type specific apoptotic process GO:0097285 4 0.018
Human
regulation of cell projection organization GO:0031344 38 0.018
hatching GO:0035188 48 0.018
monocarboxylic acid metabolic process GO:0032787 22 0.018
Zebrafish
establishment of protein localization to membrane GO:0090150 3 0.018

pop-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.074
cancer DOID:162 0 0.048
organ system cancer DOID:0050686 0 0.048
disease of anatomical entity DOID:7 0 0.038
cardiovascular system disease DOID:1287 0 0.038
large intestine cancer DOID:5672 0 0.032
gastrointestinal system cancer DOID:3119 0 0.032
intestinal cancer DOID:10155 0 0.032
musculoskeletal system disease DOID:17 0 0.025
colon cancer DOID:219 0 0.020
colorectal cancer DOID:9256 0 0.020