Caenorhabditis elegans

0 known processes

wrk-1 (CELE_F41D9.3)

Protein WRK-1

wrk-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ development GO:0048513 1102 0.552
embryo development ending in birth or egg hatching GO:0009792 2992 0.428
embryo development GO:0009790 3052 0.409
death GO:0016265 547 0.390
response to chemical GO:0042221 356 0.355
axonogenesis GO:0007409 102 0.328
neuron differentiation GO:0030182 217 0.325
locomotion GO:0040011 1634 0.319
establishment of localization GO:0051234 1171 0.316
transcription from rna polymerase ii promoter GO:0006366 149 0.303
negative regulation of cellular process GO:0048523 239 0.301
cell projection morphogenesis GO:0048858 148 0.285
oviposition GO:0018991 364 0.282
nervous system development GO:0007399 253 0.276
post embryonic development GO:0009791 2152 0.274
cell death GO:0008219 547 0.271
negative regulation of biological process GO:0048519 567 0.253
regulation of cell differentiation GO:0045595 81 0.248
single organism reproductive process GO:0044702 1196 0.240
cellular component movement GO:0006928 388 0.239
heterocycle biosynthetic process GO:0018130 187 0.236
generation of neurons GO:0048699 235 0.233
protein complex subunit organization GO:0071822 280 0.225
cell motility GO:0048870 313 0.224
system process GO:0003008 136 0.219
tissue development GO:0009888 112 0.215
chemotaxis GO:0006935 120 0.215
cellular component assembly involved in morphogenesis GO:0010927 183 0.209
transport GO:0006810 1093 0.208
taxis GO:0042330 128 0.206
localization of cell GO:0051674 313 0.200
memory GO:0007613 3 0.200
hermaphrodite genitalia development GO:0040035 734 0.200
multicellular organismal reproductive process GO:0048609 815 0.200
cell development GO:0048468 696 0.199
neuron projection guidance GO:0097485 82 0.196
negative regulation of developmental process GO:0051093 227 0.195
nucleic acid metabolic process GO:0090304 299 0.189
behavior GO:0007610 527 0.187
cell projection organization GO:0030030 231 0.185
skeletal muscle organ development GO:0060538 3 0.173
programmed cell death GO:0012501 500 0.167
macromolecule localization GO:0033036 771 0.165
single organism localization GO:1902578 518 0.165
vesicle mediated transport GO:0016192 852 0.164
head development GO:0060322 1 0.163
cell part morphogenesis GO:0032990 152 0.162
neuron development GO:0048666 199 0.157
sex differentiation GO:0007548 909 0.156
organelle organization GO:0006996 783 0.156
protein metabolic process GO:0019538 422 0.153
cellular component morphogenesis GO:0032989 318 0.153
multicellular organism reproduction GO:0032504 819 0.152
aging GO:0007568 812 0.152
regulation of multicellular organismal development GO:2000026 317 0.149
muscle tissue development GO:0060537 1 0.143
cell migration GO:0016477 306 0.143
aromatic compound biosynthetic process GO:0019438 192 0.142
regulation of macromolecule metabolic process GO:0060255 421 0.140
muscle structure development GO:0061061 191 0.140
apoptotic process GO:0006915 478 0.138
cell morphogenesis GO:0000902 163 0.136
single organism organelle organization GO:1902589 501 0.136
neuron projection development GO:0031175 187 0.136
positive regulation of rna biosynthetic process GO:1902680 102 0.136
neurogenesis GO:0022008 236 0.134
axon development GO:0061564 163 0.133
multicellular organismal reproductive behavior GO:0033057 384 0.131
catabolic process GO:0009056 318 0.130
positive regulation of cellular process GO:0048522 332 0.129
regulation of gene expression GO:0010468 366 0.128
regulation of biological quality GO:0065008 741 0.127
regulation of rna biosynthetic process GO:2001141 165 0.126
endocytosis GO:0006897 819 0.124
regulation of locomotion GO:0040012 161 0.124
regulation of metabolic process GO:0019222 478 0.123
regulation of multicellular organismal process GO:0051239 726 0.122
phosphate containing compound metabolic process GO:0006796 232 0.122
cellular component biogenesis GO:0044085 297 0.121
single organism transport GO:0044765 447 0.121
regulation of growth GO:0040008 409 0.120
neuron projection morphogenesis GO:0048812 114 0.115
cellular component assembly GO:0022607 293 0.113
cell cycle GO:0007049 526 0.110
growth GO:0040007 562 0.109
regulation of cellular metabolic process GO:0031323 305 0.109
regulation of developmental process GO:0050793 684 0.108
regulation of nucleic acid templated transcription GO:1903506 165 0.107
signal transduction GO:0007165 317 0.107
body morphogenesis GO:0010171 620 0.106
actomyosin structure organization GO:0031032 154 0.105
protein modification process GO:0036211 207 0.104
macromolecular complex subunit organization GO:0043933 320 0.103
protein complex assembly GO:0006461 186 0.102
establishment of localization in cell GO:0051649 318 0.102
response to external stimulus GO:0009605 289 0.101
receptor mediated endocytosis GO:0006898 715 0.101
multi organism reproductive process GO:0044703 867 0.100
organelle assembly GO:0070925 214 0.100
negative regulation of metabolic process GO:0009892 240 0.099
cellular protein modification process GO:0006464 207 0.098
gene expression GO:0010467 412 0.097
regulation of macromolecule biosynthetic process GO:0010556 189 0.096
reproductive structure development GO:0048608 850 0.096
nucleobase containing compound metabolic process GO:0006139 406 0.092
organic cyclic compound biosynthetic process GO:1901362 195 0.091
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.091
positive regulation of metabolic process GO:0009893 187 0.091
multicellular organismal aging GO:0010259 812 0.090
cellular protein complex assembly GO:0043623 178 0.088
cell morphogenesis involved in differentiation GO:0000904 112 0.087
determination of adult lifespan GO:0008340 812 0.087
macromolecule biosynthetic process GO:0009059 250 0.085
positive regulation of transcription dna templated GO:0045893 102 0.084
gastrulation GO:0007369 58 0.084
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.084
anatomical structure formation involved in morphogenesis GO:0048646 250 0.084
macromolecule modification GO:0043412 218 0.083
developmental growth GO:0048589 412 0.082
multi organism reproductive behavior GO:0044705 387 0.082
striated muscle contraction involved in embryonic body morphogenesis GO:0061199 13 0.079
negative regulation of multicellular organismal process GO:0051241 236 0.078
striated muscle cell development GO:0055002 157 0.078
positive regulation of developmental growth GO:0048639 354 0.078
actin cytoskeleton organization GO:0030036 184 0.077
positive regulation of developmental process GO:0051094 408 0.075
cytoskeleton organization GO:0007010 339 0.075
positive regulation of neuron differentiation GO:0045666 4 0.075
protein complex biogenesis GO:0070271 186 0.075
biosynthetic process GO:0009058 323 0.075
macromolecular complex assembly GO:0065003 193 0.075
maintenance of location GO:0051235 580 0.074
cellular macromolecule biosynthetic process GO:0034645 247 0.074
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.074
gamete generation GO:0007276 461 0.073
multi organism behavior GO:0051705 389 0.072
cell cycle process GO:0022402 482 0.071
reproductive system development GO:0061458 850 0.071
regulation of developmental growth GO:0048638 389 0.070
tube development GO:0035295 126 0.069
signaling GO:0023052 401 0.069
positive regulation of rna metabolic process GO:0051254 103 0.069
epithelium development GO:0060429 68 0.069
muscle cell differentiation GO:0042692 171 0.068
neurological system process GO:0050877 53 0.068
digestive tract development GO:0048565 122 0.068
lipid storage GO:0019915 565 0.068
rna biosynthetic process GO:0032774 169 0.067
multi multicellular organism process GO:0044706 390 0.067
cellular biosynthetic process GO:0044249 315 0.066
positive regulation of growth GO:0045927 369 0.066
lipid localization GO:0010876 573 0.065
striated muscle myosin thick filament assembly GO:0071688 138 0.065
cellular nitrogen compound biosynthetic process GO:0044271 192 0.065
organic substance catabolic process GO:1901575 294 0.064
nucleobase containing compound biosynthetic process GO:0034654 184 0.064
development of primary sexual characteristics GO:0045137 840 0.063
tissue morphogenesis GO:0048729 65 0.063
rna metabolic process GO:0016070 228 0.063
tube morphogenesis GO:0035239 79 0.063
phosphorus metabolic process GO:0006793 232 0.060
innate immune response GO:0045087 190 0.060
sexual reproduction GO:0019953 546 0.060
muscle cell development GO:0055001 158 0.060
gonad development GO:0008406 840 0.058
single organism signaling GO:0044700 401 0.056
post embryonic organ development GO:0048569 336 0.056
spermatogenesis GO:0007283 41 0.056
regulation of transcription dna templated GO:0006355 164 0.055
myosin filament assembly GO:0031034 138 0.055
regulation of cellular biosynthetic process GO:0031326 189 0.053
regulation of neuron differentiation GO:0045664 40 0.053
regulation of cell development GO:0060284 49 0.052
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.052
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.052
striated muscle cell differentiation GO:0051146 158 0.052
regulation of response to wounding GO:1903034 1 0.051
cell surface receptor signaling pathway GO:0007166 149 0.051
cell fate commitment GO:0045165 139 0.051
regulation of cell morphogenesis GO:0022604 40 0.051
positive regulation of gene expression GO:0010628 112 0.050
positive regulation of nucleic acid templated transcription GO:1903508 102 0.049
regulation of cell motility GO:2000145 57 0.049
reproductive behavior GO:0019098 387 0.049
myofibril assembly GO:0030239 154 0.048
regulation of primary metabolic process GO:0080090 292 0.048
nucleoside phosphate metabolic process GO:0006753 108 0.048
protein catabolic process GO:0030163 162 0.047
nucleic acid templated transcription GO:0097659 169 0.047
cellular protein metabolic process GO:0044267 279 0.046
regulation of nitrogen compound metabolic process GO:0051171 222 0.046
nucleoside metabolic process GO:0009116 99 0.045
cell recognition GO:0008037 85 0.045
negative regulation of cellular metabolic process GO:0031324 95 0.045
regulation of rna metabolic process GO:0051252 173 0.045
muscle contraction GO:0006936 43 0.045
cellular localization GO:0051641 360 0.045
organic substance biosynthetic process GO:1901576 323 0.045
positive regulation of neurogenesis GO:0050769 4 0.044
protein phosphorylation GO:0006468 85 0.044
regulation of biosynthetic process GO:0009889 189 0.044
transcription dna templated GO:0006351 168 0.043
digestive tract morphogenesis GO:0048546 76 0.043
macromolecule catabolic process GO:0009057 202 0.043
multicellular organism growth GO:0035264 385 0.042
positive regulation of multicellular organism growth GO:0040018 352 0.042
oogenesis GO:0048477 229 0.041
digestive system development GO:0055123 122 0.041
phosphorylation GO:0016310 116 0.041
embryonic morphogenesis GO:0048598 152 0.040
regulation of multicellular organism growth GO:0040014 373 0.040
actin filament based process GO:0030029 191 0.040
regulation of response to stimulus GO:0048583 243 0.040
intracellular signal transduction GO:0035556 96 0.040
regulation of cell proliferation GO:0042127 105 0.039
sensory organ morphogenesis GO:0090596 2 0.039
regulation of filopodium assembly GO:0051489 2 0.039
neuron recognition GO:0008038 83 0.039
establishment of spindle localization GO:0051293 51 0.039
response to organic substance GO:0010033 131 0.038
myosin filament organization GO:0031033 138 0.038
cell matrix adhesion GO:0007160 1 0.038
pattern specification process GO:0007389 59 0.038
regulation of cellular component organization GO:0051128 248 0.037
germ cell development GO:0007281 351 0.037
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.036
negative regulation of macromolecule metabolic process GO:0010605 229 0.036
regulation of cell migration GO:0030334 55 0.036
cellular response to chemical stimulus GO:0070887 129 0.035
regulation of organ morphogenesis GO:2000027 4 0.035
positive regulation of macromolecule metabolic process GO:0010604 149 0.034
cellular macromolecular complex assembly GO:0034622 184 0.034
meiotic cell cycle GO:0051321 335 0.033
cell adhesion GO:0007155 21 0.033
biological adhesion GO:0022610 21 0.033
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.033
nucleobase containing compound catabolic process GO:0034655 114 0.033
small molecule metabolic process GO:0044281 186 0.033
cell growth GO:0016049 44 0.032
axon guidance GO:0007411 82 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.032
defense response GO:0006952 296 0.032
positive regulation of multicellular organismal process GO:0051240 417 0.032
negative regulation of gene expression GO:0010629 217 0.031
cell substrate adhesion GO:0031589 1 0.031
cell proliferation GO:0008283 116 0.031
secretion GO:0046903 147 0.031
cellular nitrogen compound catabolic process GO:0044270 119 0.031
muscle organ development GO:0007517 26 0.031
protein localization GO:0008104 205 0.031
regulation of cellular component movement GO:0051270 62 0.031
organ morphogenesis GO:0009887 67 0.030
regulation of cell cycle GO:0051726 194 0.030
negative regulation of ion transmembrane transport GO:0034766 3 0.029
negative regulation of cellular biosynthetic process GO:0031327 65 0.029
regulation of cell projection assembly GO:0060491 3 0.029
feeding behavior GO:0007631 70 0.029
regulation of system process GO:0044057 27 0.028
positive regulation of cellular metabolic process GO:0031325 178 0.028
inductive cell migration GO:0040039 145 0.028
synaptic transmission GO:0007268 106 0.028
regulation of epithelial cell proliferation GO:0050678 1 0.028
genitalia development GO:0048806 741 0.027
regulation of neurogenesis GO:0050767 40 0.026
chemosensory behavior GO:0007635 33 0.026
epithelial cell proliferation GO:0050673 1 0.026
carbohydrate derivative metabolic process GO:1901135 141 0.025
meiotic cell cycle process GO:1903046 170 0.025
regulation of epithelial cell differentiation GO:0030856 4 0.025
cellular response to organic substance GO:0071310 119 0.025
single organism cellular localization GO:1902580 72 0.025
negative regulation of biosynthetic process GO:0009890 65 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.025
positive regulation of biosynthetic process GO:0009891 109 0.025
response to abiotic stimulus GO:0009628 152 0.024
meiotic nuclear division GO:0007126 300 0.024
vulval development GO:0040025 333 0.024
positive regulation of cell projection organization GO:0031346 4 0.024
nucleotide metabolic process GO:0009117 108 0.023
cell division GO:0051301 262 0.023
cognition GO:0050890 27 0.023
cell projection assembly GO:0030031 35 0.023
regulation of cytoskeleton organization GO:0051493 41 0.023
learning or memory GO:0007611 27 0.023
establishment of protein localization to membrane GO:0090150 3 0.023
cell cell signaling GO:0007267 118 0.023
immune response GO:0006955 192 0.023
regulation of localization GO:0032879 194 0.023
female gamete generation GO:0007292 254 0.023
ion transport GO:0006811 113 0.023
cellular protein localization GO:0034613 75 0.022
negative regulation of cell communication GO:0010648 61 0.022
membrane organization GO:0061024 135 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
response to wounding GO:0009611 4 0.022
regulation of anatomical structure size GO:0090066 46 0.022
epithelial tube morphogenesis GO:0060562 1 0.022
intracellular receptor signaling pathway GO:0030522 2 0.022
establishment or maintenance of cell polarity GO:0007163 63 0.022
ribonucleoside catabolic process GO:0042454 77 0.022
organelle fission GO:0048285 363 0.021
muscle system process GO:0003012 43 0.021
regulation of cell communication GO:0010646 176 0.021
axon extension GO:0048675 37 0.021
organic substance transport GO:0071702 113 0.021
regulation of phosphate metabolic process GO:0019220 81 0.021
negative regulation of signaling GO:0023057 61 0.020
developmental process involved in reproduction GO:0003006 1165 0.020
positive regulation of cellular biosynthetic process GO:0031328 109 0.020
organonitrogen compound metabolic process GO:1901564 151 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.020
regulation of post embryonic development GO:0048580 260 0.020
single organism catabolic process GO:0044712 129 0.020
positive regulation of neuron projection development GO:0010976 4 0.019
regulation of apoptotic process GO:0042981 36 0.019
regulation of cell projection organization GO:0031344 38 0.019
regulation of signaling GO:0023051 172 0.019
negative regulation of signal transduction GO:0009968 60 0.019
positive regulation of response to stimulus GO:0048584 55 0.019
microtubule based process GO:0007017 182 0.019
integrin mediated signaling pathway GO:0007229 1 0.018
cell type specific apoptotic process GO:0097285 4 0.018
regulation of vulval development GO:0040028 248 0.018
regulation of cell death GO:0010941 65 0.018
cytoskeleton dependent cytokinesis GO:0061640 35 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.018
regulation of nervous system development GO:0051960 41 0.018
anterior posterior pattern specification GO:0009952 27 0.017
maintenance of protein location GO:0045185 15 0.017
cellular catabolic process GO:0044248 199 0.017
organic acid metabolic process GO:0006082 47 0.017
regulation of molecular function GO:0065009 89 0.017
establishment of cell polarity GO:0030010 46 0.017
enzyme linked receptor protein signaling pathway GO:0007167 50 0.017
long term memory GO:0007616 2 0.017
regulation of neuron projection development GO:0010975 31 0.017
transmembrane transport GO:0055085 110 0.017
single organism behavior GO:0044708 83 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.016
regulation of cellular component size GO:0032535 40 0.016
regulation of anatomical structure morphogenesis GO:0022603 51 0.016
embryonic body morphogenesis GO:0010172 49 0.016
response to endogenous stimulus GO:0009719 33 0.016
nucleobase containing small molecule metabolic process GO:0055086 115 0.016
aromatic compound catabolic process GO:0019439 116 0.016
purine ribonucleoside catabolic process GO:0046130 75 0.016
ribose phosphate metabolic process GO:0019693 99 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.015
calcium mediated signaling GO:0019722 3 0.015
axonal fasciculation GO:0007413 79 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
regulation of synaptic transmission GO:0050804 34 0.015
organic cyclic compound catabolic process GO:1901361 119 0.015
cytokinesis GO:0000910 80 0.015
spindle localization GO:0051653 51 0.014
regulation of signal transduction GO:0009966 135 0.014
ribonucleoside metabolic process GO:0009119 98 0.014
positive regulation of cell migration GO:0030335 3 0.014
oxoacid metabolic process GO:0043436 47 0.014
negative regulation of rna biosynthetic process GO:1902679 53 0.014
negative regulation of nucleic acid templated transcription GO:1903507 53 0.014
protein oligomerization GO:0051259 4 0.014
cellular response to stress GO:0033554 162 0.014
regulation of gene expression epigenetic GO:0040029 163 0.014
muscle attachment GO:0016203 3 0.014
regulation of programmed cell death GO:0043067 50 0.014
molting cycle GO:0042303 281 0.014
organophosphate metabolic process GO:0019637 125 0.013
mitotic cell cycle process GO:1903047 194 0.013
cellular macromolecule localization GO:0070727 75 0.013
regulation of nematode larval development GO:0061062 260 0.013
negative regulation of neurogenesis GO:0050768 4 0.013
regulation of defecation rhythm GO:2000746 3 0.013
canonical wnt signaling pathway GO:0060070 3 0.013
regeneration GO:0031099 4 0.013
male gamete generation GO:0048232 41 0.013
sensory perception GO:0007600 27 0.013
chromosome segregation GO:0007059 180 0.013
secretion by cell GO:0032940 138 0.013
cellular response to endogenous stimulus GO:0071495 32 0.013
purine nucleoside metabolic process GO:0042278 92 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
positive regulation of cell communication GO:0010647 69 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.012
regulation of catalytic activity GO:0050790 78 0.012
regulation of lamellipodium assembly GO:0010591 1 0.012
muscle organ morphogenesis GO:0048644 4 0.012
single organism membrane organization GO:0044802 35 0.012
positive regulation of cell cycle GO:0045787 55 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
regulation of transport GO:0051049 91 0.012
positive regulation of intracellular transport GO:0032388 2 0.012
establishment of organelle localization GO:0051656 123 0.012
carbohydrate derivative catabolic process GO:1901136 82 0.012
negative regulation of nematode larval development GO:0061064 208 0.012
rna interference GO:0016246 137 0.012
cell junction organization GO:0034330 18 0.012
hyperosmotic response GO:0006972 19 0.012
filopodium assembly GO:0046847 2 0.012
negative regulation of transmembrane transport GO:0034763 3 0.012
signal transduction by phosphorylation GO:0023014 31 0.012
regulation of neuromuscular synaptic transmission GO:1900073 1 0.012
regulation of cell division GO:0051302 142 0.011
carbohydrate metabolic process GO:0005975 34 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
ovulation GO:0030728 33 0.011
endoderm development GO:0007492 20 0.011
negative regulation of vulval development GO:0040027 206 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
regulation of cell fate commitment GO:0010453 22 0.011
regulation of phosphorylation GO:0042325 45 0.011
glycosyl compound metabolic process GO:1901657 100 0.011
regulation of organelle organization GO:0033043 164 0.011
organonitrogen compound biosynthetic process GO:1901566 44 0.011
purine containing compound metabolic process GO:0072521 95 0.011
phagocytosis GO:0006909 115 0.011
nucleoside phosphate catabolic process GO:1901292 77 0.010
amine metabolic process GO:0009308 15 0.010
regulation of phosphorus metabolic process GO:0051174 81 0.010
posttranscriptional gene silencing GO:0016441 143 0.010
posttranscriptional gene silencing by rna GO:0035194 143 0.010
negative regulation of transcription dna templated GO:0045892 53 0.010
epithelial cell differentiation GO:0030855 17 0.010
regulation of behavior GO:0050795 97 0.010
purine nucleoside triphosphate metabolic process GO:0009144 87 0.010
negative regulation of neuron differentiation GO:0045665 4 0.010
cellular ketone metabolic process GO:0042180 14 0.010
cellular amine metabolic process GO:0044106 15 0.010

wrk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.014