Caenorhabditis elegans

138 known processes

gsk-3 (CELE_Y18D10A.5)

Protein GSK-3

gsk-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
wnt signaling pathway GO:0016055 27 0.537
signal transduction GO:0007165 317 0.488
transport GO:0006810 1093 0.419
embryo development ending in birth or egg hatching GO:0009792 2992 0.376
signaling GO:0023052 401 0.352
cell surface receptor signaling pathway GO:0007166 149 0.349
multicellular organismal reproductive process GO:0048609 815 0.328
organ development GO:0048513 1102 0.312
establishment of localization GO:0051234 1171 0.291
cell morphogenesis GO:0000902 163 0.291
Human Mouse Rat Fly
nervous system development GO:0007399 253 0.287
Human Mouse Rat Fly
endocytosis GO:0006897 819 0.283
generation of neurons GO:0048699 235 0.279
Mouse Rat
neuron differentiation GO:0030182 217 0.275
Mouse Rat
vesicle mediated transport GO:0016192 852 0.247
cellular component morphogenesis GO:0032989 318 0.240
Human Mouse Rat Fly
embryo development GO:0009790 3052 0.239
cell development GO:0048468 696 0.236
axon development GO:0061564 163 0.228
Mouse
locomotion GO:0040011 1634 0.219
neuron projection guidance GO:0097485 82 0.214
neurogenesis GO:0022008 236 0.209
Mouse Rat
cellular localization GO:0051641 360 0.203
hermaphrodite genitalia development GO:0040035 734 0.202
neuron projection development GO:0031175 187 0.197
Mouse Rat
cell projection morphogenesis GO:0048858 148 0.192
Mouse Rat
cell projection organization GO:0030030 231 0.192
Mouse Rat
vulval development GO:0040025 333 0.182
response to external stimulus GO:0009605 289 0.179
Rat Fly
cell migration GO:0016477 306 0.178
single organism signaling GO:0044700 401 0.171
reproductive structure development GO:0048608 850 0.171
single organism transport GO:0044765 447 0.162
negative regulation of cellular process GO:0048523 239 0.159
genitalia development GO:0048806 741 0.158
response to wounding GO:0009611 4 0.157
cell motility GO:0048870 313 0.157
neuron projection morphogenesis GO:0048812 114 0.153
Mouse Rat
multi organism reproductive process GO:0044703 867 0.148
post embryonic development GO:0009791 2152 0.146
mitotic spindle organization GO:0007052 81 0.143
regulation of multicellular organismal process GO:0051239 726 0.141
Mouse Rat Fly
post embryonic organ development GO:0048569 336 0.140
Fly
single organism cellular localization GO:1902580 72 0.140
death GO:0016265 547 0.138
Human Mouse Rat
regulation of phosphorus metabolic process GO:0051174 81 0.138
Human Mouse Rat Fly
axon guidance GO:0007411 82 0.137
multicellular organismal reproductive behavior GO:0033057 384 0.137
organelle localization GO:0051640 127 0.136
phosphorus metabolic process GO:0006793 232 0.134
single organism organelle organization GO:1902589 501 0.133
localization of cell GO:0051674 313 0.129
neuron development GO:0048666 199 0.129
Mouse Rat
chemotaxis GO:0006935 120 0.126
organelle fission GO:0048285 363 0.126
Fly
developmental process involved in reproduction GO:0003006 1165 0.124
regulation of cell communication GO:0010646 176 0.123
single organism localization GO:1902578 518 0.122
regulation of biological quality GO:0065008 741 0.120
Mouse Rat Fly
establishment of localization in cell GO:0051649 318 0.120
head development GO:0060322 1 0.117
Human
multicellular organism reproduction GO:0032504 819 0.116
negative regulation of wnt signaling pathway GO:0030178 6 0.114
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.111
Mouse Rat
positive regulation of vulval development GO:0040026 52 0.111
regulation of signal transduction GO:0009966 135 0.109
regulation of vulval development GO:0040028 248 0.108
cellular component movement GO:0006928 388 0.107
behavior GO:0007610 527 0.106
Fly
development of primary sexual characteristics GO:0045137 840 0.106
sex differentiation GO:0007548 909 0.104
gonad development GO:0008406 840 0.103
single organism reproductive process GO:0044702 1196 0.103
regulation of cytoplasmic transport GO:1903649 3 0.102
Human
multi organism behavior GO:0051705 389 0.101
macromolecule localization GO:0033036 771 0.101
taxis GO:0042330 128 0.100
organelle organization GO:0006996 783 0.100
regulation of cellular metabolic process GO:0031323 305 0.100
Human Mouse Rat Fly
positive regulation of nematode larval development GO:0061063 54 0.100
cell part morphogenesis GO:0032990 152 0.100
Mouse Rat
regulation of developmental process GO:0050793 684 0.100
Mouse Rat Fly
protein complex subunit organization GO:0071822 280 0.099
regulation of response to stimulus GO:0048583 243 0.099
regulation of locomotion GO:0040012 161 0.099
nucleobase containing compound metabolic process GO:0006139 406 0.094
Human Mouse
gamete generation GO:0007276 461 0.093
negative regulation of biological process GO:0048519 567 0.093
biosynthetic process GO:0009058 323 0.093
Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.093
Mouse
phosphate containing compound metabolic process GO:0006796 232 0.092
reproductive behavior GO:0019098 387 0.090
regulation of macromolecule metabolic process GO:0060255 421 0.088
Mouse Rat Fly
reproductive system development GO:0061458 850 0.088
organic substance catabolic process GO:1901575 294 0.087
Human Mouse Fly
microtubule based process GO:0007017 182 0.086
cytoskeleton organization GO:0007010 339 0.085
receptor mediated endocytosis GO:0006898 715 0.084
spindle organization GO:0007051 92 0.082
cellular catabolic process GO:0044248 199 0.082
Human Mouse Fly
cell cycle process GO:0022402 482 0.081
regulation of nematode larval development GO:0061062 260 0.081
cell fate commitment GO:0045165 139 0.078
oogenesis GO:0048477 229 0.076
Fly
maintenance of location GO:0051235 580 0.075
positive regulation of locomotion GO:0040017 42 0.075
sensory organ morphogenesis GO:0090596 2 0.073
regulation of metabolic process GO:0019222 478 0.072
Human Mouse Rat Fly
gene expression GO:0010467 412 0.070
macromolecule catabolic process GO:0009057 202 0.070
Mouse Fly
lipid storage GO:0019915 565 0.069
multi organism reproductive behavior GO:0044705 387 0.068
positive regulation of phosphate metabolic process GO:0045937 56 0.068
Human Mouse
protein localization GO:0008104 205 0.068
macromolecule modification GO:0043412 218 0.068
anatomical structure formation involved in morphogenesis GO:0048646 250 0.067
Mouse
germ cell development GO:0007281 351 0.067
gastrulation GO:0007369 58 0.066
mitotic cell cycle process GO:1903047 194 0.065
lipid localization GO:0010876 573 0.065
cellular biosynthetic process GO:0044249 315 0.063
Mouse
positive regulation of developmental process GO:0051094 408 0.063
Mouse
body morphogenesis GO:0010171 620 0.063
establishment of organelle localization GO:0051656 123 0.063
nucleoside triphosphate metabolic process GO:0009141 87 0.063
Human
regulation of nucleocytoplasmic transport GO:0046822 3 0.063
Human
regulation of post embryonic development GO:0048580 260 0.063
cellular protein metabolic process GO:0044267 279 0.063
regulation of wnt signaling pathway GO:0030111 9 0.062
determination of adult lifespan GO:0008340 812 0.062
macromolecular complex subunit organization GO:0043933 320 0.061
regulation of cell migration GO:0030334 55 0.060
regulation of growth GO:0040008 409 0.060
Mouse Fly
regulation of signaling GO:0023051 172 0.059
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.059
regulation of multicellular organism growth GO:0040014 373 0.059
positive regulation of phosphorus metabolic process GO:0010562 56 0.059
Human Mouse
small molecule metabolic process GO:0044281 186 0.058
Human Mouse
organic cyclic compound biosynthetic process GO:1901362 195 0.058
Mouse
establishment of spindle localization GO:0051293 51 0.057
multicellular organism growth GO:0035264 385 0.057
regulation of catabolic process GO:0009894 57 0.057
Human Mouse Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.056
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 229 0.056
Rat Fly
negative regulation of developmental process GO:0051093 227 0.056
Mouse Rat Fly
multicellular organismal aging GO:0010259 812 0.055
positive regulation of catalytic activity GO:0043085 59 0.055
Human Mouse
female gamete generation GO:0007292 254 0.055
Fly
positive regulation of metabolic process GO:0009893 187 0.055
Human Mouse Fly
cell death GO:0008219 547 0.054
Human Mouse Rat
regulation of cellular component organization GO:0051128 248 0.054
negative regulation of multicellular organismal process GO:0051241 236 0.054
Mouse Rat Fly
organonitrogen compound metabolic process GO:1901564 151 0.053
Human Mouse
regulation of primary metabolic process GO:0080090 292 0.053
Human Mouse Rat Fly
regulation of transport GO:0051049 91 0.052
Human Mouse
oviposition GO:0018991 364 0.052
nucleotide metabolic process GO:0009117 108 0.052
Human Mouse
regulation of transcription dna templated GO:0006355 164 0.052
Mouse
regulation of nitrogen compound metabolic process GO:0051171 222 0.052
Human Mouse
multi multicellular organism process GO:0044706 390 0.052
ribose phosphate metabolic process GO:0019693 99 0.051
Human Mouse
canonical wnt signaling pathway GO:0060070 3 0.051
Human Mouse
regulation of cell motility GO:2000145 57 0.050
sexual reproduction GO:0019953 546 0.050
membrane organization GO:0061024 135 0.050
muscle tissue development GO:0060537 1 0.050
Mouse
positive regulation of developmental growth GO:0048639 354 0.050
Mouse
regulation of rna metabolic process GO:0051252 173 0.050
Mouse
cellular component biogenesis GO:0044085 297 0.049
Human Fly
muscle cell development GO:0055001 158 0.049
Mouse
cellular protein modification process GO:0006464 207 0.048
organophosphate metabolic process GO:0019637 125 0.048
Human Mouse
regulation of catalytic activity GO:0050790 78 0.048
Human Mouse Rat Fly
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.048
Mouse
positive regulation of cell migration GO:0030335 3 0.047
growth GO:0040007 562 0.047
Mouse Fly
negative regulation of cell communication GO:0010648 61 0.047
establishment or maintenance of cell polarity GO:0007163 63 0.047
Rat Fly
mapk cascade GO:0000165 31 0.047
Rat Fly
aging GO:0007568 812 0.046
mating GO:0007618 34 0.046
cell cycle GO:0007049 526 0.046
actin filament based process GO:0030029 191 0.046
regulation of cell cycle process GO:0010564 145 0.046
negative regulation of signaling GO:0023057 61 0.046
regulation of cellular protein metabolic process GO:0032268 75 0.046
Mouse Rat Fly
regulation of localization GO:0032879 194 0.046
synaptic transmission GO:0007268 106 0.045
Rat Fly
regulation of cell cycle GO:0051726 194 0.045
small gtpase mediated signal transduction GO:0007264 32 0.045
intracellular signal transduction GO:0035556 96 0.044
Human Mouse Rat Fly
regulation of gene expression GO:0010468 366 0.044
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.044
Human Mouse
muscle structure development GO:0061061 191 0.044
Mouse
single organism intracellular transport GO:1902582 70 0.043
Human Mouse
ras protein signal transduction GO:0007265 31 0.043
regulation of epithelial cell proliferation GO:0050678 1 0.043
response to chemical GO:0042221 356 0.043
Human Mouse Rat Fly
macromolecule biosynthetic process GO:0009059 250 0.043
Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.042
Human Mouse Fly
inductive cell migration GO:0040039 145 0.042
regulation of multicellular organismal development GO:2000026 317 0.042
Mouse Rat Fly
negative regulation of gene expression GO:0010629 217 0.042
regulation of intracellular signal transduction GO:1902531 77 0.042
Human Mouse Rat Fly
defense response GO:0006952 296 0.041
signal transduction by phosphorylation GO:0023014 31 0.041
Rat Fly
apoptotic process GO:0006915 478 0.041
Human Mouse Rat
adult behavior GO:0030534 3 0.041
protein complex biogenesis GO:0070271 186 0.040
Human
nucleic acid templated transcription GO:0097659 169 0.040
Mouse
regeneration GO:0031099 4 0.040
cell cell signaling GO:0007267 118 0.040
Rat Fly
negative regulation of vulval development GO:0040027 206 0.040
negative regulation of cellular metabolic process GO:0031324 95 0.039
Rat Fly
negative regulation of signal transduction GO:0009968 60 0.039
cellular response to stress GO:0033554 162 0.038
Human Mouse Fly
negative regulation of nematode larval development GO:0061064 208 0.038
nucleic acid metabolic process GO:0090304 299 0.038
Mouse
purine containing compound catabolic process GO:0072523 75 0.038
Human
aromatic compound biosynthetic process GO:0019438 192 0.038
Mouse
transcription from rna polymerase ii promoter GO:0006366 149 0.037
Mouse
meiotic cell cycle GO:0051321 335 0.037
Fly
cellular macromolecule localization GO:0070727 75 0.037
Human Mouse
organic cyclic compound catabolic process GO:1901361 119 0.037
Human
ribosome biogenesis GO:0042254 4 0.036
positive regulation of growth GO:0045927 369 0.036
Mouse
positive regulation of cell communication GO:0010647 69 0.036
Mouse
negative regulation of metabolic process GO:0009892 240 0.036
Human Rat Fly
heterocycle biosynthetic process GO:0018130 187 0.036
Mouse
carbohydrate derivative metabolic process GO:1901135 141 0.036
Human Mouse
positive regulation of intracellular transport GO:0032388 2 0.036
Human Mouse
regulation of cell morphogenesis GO:0022604 40 0.035
Mouse Rat
positive regulation of signaling GO:0023056 66 0.035
Mouse
establishment of cell polarity GO:0030010 46 0.035
Rat Fly
regulation of macromolecule biosynthetic process GO:0010556 189 0.035
Mouse
epithelial cell proliferation GO:0050673 1 0.035
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.035
Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.034
Mouse Fly
regulation of canonical wnt signaling pathway GO:0060828 1 0.034
muscle cell differentiation GO:0042692 171 0.034
Mouse
establishment of mitotic spindle localization GO:0040001 41 0.034
actin cytoskeleton organization GO:0030036 184 0.034
developmental growth GO:0048589 412 0.034
Mouse Fly
organelle assembly GO:0070925 214 0.034
regulation of cellular component movement GO:0051270 62 0.034
enzyme linked receptor protein signaling pathway GO:0007167 50 0.034
Human Mouse
cellular component assembly GO:0022607 293 0.033
Human Fly
negative regulation of post embryonic development GO:0048581 208 0.033
regulation of gene expression epigenetic GO:0040029 163 0.033
Mouse
neuron recognition GO:0008038 83 0.033
spindle localization GO:0051653 51 0.033
regulation of organelle organization GO:0033043 164 0.033
regulation of developmental growth GO:0048638 389 0.032
Mouse Fly
nucleoside metabolic process GO:0009116 99 0.032
Human
protein metabolic process GO:0019538 422 0.032
cellular macromolecule biosynthetic process GO:0034645 247 0.032
Mouse
positive regulation of response to stimulus GO:0048584 55 0.032
Mouse
protein modification process GO:0036211 207 0.032
purine containing compound metabolic process GO:0072521 95 0.032
Human Mouse
purine nucleoside triphosphate metabolic process GO:0009144 87 0.032
Human
regulation of cell differentiation GO:0045595 81 0.031
Mouse Rat Fly
intracellular transport GO:0046907 77 0.031
Human Mouse
positive regulation of cellular catabolic process GO:0031331 35 0.031
Human Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.031
Mouse
system process GO:0003008 136 0.031
Mouse Fly
protein catabolic process GO:0030163 162 0.030
Mouse Fly
purine ribonucleoside metabolic process GO:0046128 92 0.030
Human
response to abiotic stimulus GO:0009628 152 0.030
Rat
nucleoside phosphate metabolic process GO:0006753 108 0.030
Human Mouse
epithelium development GO:0060429 68 0.030
Fly
cell division GO:0051301 262 0.030
Fly
cell recognition GO:0008037 85 0.030
positive regulation of biosynthetic process GO:0009891 109 0.030
Mouse
single organism behavior GO:0044708 83 0.029
Fly
positive regulation of multicellular organism growth GO:0040018 352 0.029
organonitrogen compound catabolic process GO:1901565 90 0.029
Human
organic substance biosynthetic process GO:1901576 323 0.029
Mouse
regulation of cytoskeleton organization GO:0051493 41 0.029
organic substance transport GO:0071702 113 0.029
Human Mouse
regulation of gtpase activity GO:0043087 30 0.029
Human
detection of external stimulus GO:0009581 4 0.028
phosphorylation GO:0016310 116 0.028
positive regulation of catabolic process GO:0009896 38 0.028
Human Mouse Fly
ribonucleoside metabolic process GO:0009119 98 0.028
Human
positive regulation of cellular process GO:0048522 332 0.027
Human Mouse Rat Fly
rna metabolic process GO:0016070 228 0.027
Mouse
positive regulation of intracellular signal transduction GO:1902533 24 0.027
regulation of protein metabolic process GO:0051246 81 0.027
Mouse Rat Fly
striated muscle cell development GO:0055002 157 0.027
Mouse
single organism catabolic process GO:0044712 129 0.027
Human Fly
tube morphogenesis GO:0035239 79 0.027
catabolic process GO:0009056 318 0.027
Human Mouse Fly
skeletal muscle organ development GO:0060538 3 0.027
macromolecular complex assembly GO:0065003 193 0.027
Human
positive regulation of rna biosynthetic process GO:1902680 102 0.026
Mouse
heterocycle catabolic process GO:0046700 119 0.026
Human
anterior posterior axis specification GO:0009948 17 0.026
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.026
Mouse
embryonic pattern specification GO:0009880 21 0.026
Fly
protein complex assembly GO:0006461 186 0.026
Human
regulation of stem cell differentiation GO:2000736 1 0.026
Mouse
carbohydrate derivative catabolic process GO:1901136 82 0.025
Human
regulation of neurogenesis GO:0050767 40 0.025
Mouse Rat
regulation of cell fate specification GO:0042659 22 0.025
digestive tract development GO:0048565 122 0.025
regulation of phosphate metabolic process GO:0019220 81 0.025
Human Mouse Rat Fly
cellular response to abiotic stimulus GO:0071214 4 0.025
Rat
purine nucleoside triphosphate catabolic process GO:0009146 72 0.025
Human
protein phosphorylation GO:0006468 85 0.025
regionalization GO:0003002 31 0.025
Fly
cellular response to organic substance GO:0071310 119 0.025
Human Mouse
regulation of protein targeting GO:1903533 3 0.024
Human
regulation of gtp catabolic process GO:0033124 32 0.024
Human
regulation of cell development GO:0060284 49 0.024
Mouse Rat
meiotic nuclear division GO:0007126 300 0.024
Fly
axonogenesis GO:0007409 102 0.024
Mouse
immune response GO:0006955 192 0.024
nucleobase containing compound catabolic process GO:0034655 114 0.024
Human
posttranscriptional regulation of gene expression GO:0010608 166 0.024
axis specification GO:0009798 23 0.024
embryonic morphogenesis GO:0048598 152 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
adult locomotory behavior GO:0008344 1 0.023
purine nucleotide catabolic process GO:0006195 75 0.023
Human
positive regulation of epithelial cell proliferation GO:0050679 1 0.023
pattern specification process GO:0007389 59 0.023
Fly
cell proliferation GO:0008283 116 0.023
regulation of map kinase activity GO:0043405 13 0.023
Rat Fly
regulation of neuron projection development GO:0010975 31 0.023
Mouse Rat
glycosyl compound metabolic process GO:1901657 100 0.023
Human
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
Human Mouse
posttranscriptional gene silencing GO:0016441 143 0.022
positive regulation of jnk cascade GO:0046330 3 0.022
posttranscriptional gene silencing by rna GO:0035194 143 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.022
Mouse Rat
positive regulation of neurogenesis GO:0050769 4 0.022
Mouse
programmed cell death GO:0012501 500 0.022
Human Mouse Rat
regulation of molecular function GO:0065009 89 0.022
Human Mouse Rat Fly
asymmetric protein localization GO:0008105 35 0.022
regulation of jun kinase activity GO:0043506 3 0.022
Fly
positive regulation of cell cycle GO:0045787 55 0.021
Fly
proteolysis GO:0006508 61 0.021
Mouse Fly
regulation of nuclear division GO:0051783 115 0.021
Fly
molting cycle GO:0042303 281 0.021
Fly
regulation of anatomical structure morphogenesis GO:0022603 51 0.021
Mouse Rat
positive regulation of protein kinase activity GO:0045860 18 0.021
digestive system development GO:0055123 122 0.021
aromatic compound catabolic process GO:0019439 116 0.021
Human
regulation of cellular catabolic process GO:0031329 51 0.021
Human Mouse Fly
digestive tract morphogenesis GO:0048546 76 0.021
mitotic nuclear division GO:0007067 89 0.021
Fly
response to organic substance GO:0010033 131 0.021
Human Mouse
purine ribonucleoside catabolic process GO:0046130 75 0.021
Human
nucleobase containing small molecule metabolic process GO:0055086 115 0.021
Human Mouse
locomotory behavior GO:0007626 40 0.020
cellular component assembly involved in morphogenesis GO:0010927 183 0.020
regulation of cell proliferation GO:0042127 105 0.020
cellular nitrogen compound biosynthetic process GO:0044271 192 0.020
Mouse
gtp catabolic process GO:0006184 46 0.020
Human
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.020
regulation of lipid metabolic process GO:0019216 4 0.020
cellular response to chemical stimulus GO:0070887 129 0.020
Human Mouse
modification dependent macromolecule catabolic process GO:0043632 32 0.020
Mouse Fly
cellular protein complex assembly GO:0043623 178 0.020
protein localization to organelle GO:0033365 37 0.020
Human Mouse
striated muscle cell differentiation GO:0051146 158 0.020
Mouse
regulation of phosphorylation GO:0042325 45 0.020
Mouse Rat Fly
secretion by cell GO:0032940 138 0.020
neurological system process GO:0050877 53 0.020
Fly
cell type specific apoptotic process GO:0097285 4 0.020
gene silencing by rna GO:0031047 143 0.020
rna biosynthetic process GO:0032774 169 0.019
Mouse
nucleoside phosphate catabolic process GO:1901292 77 0.019
Human
protein oligomerization GO:0051259 4 0.019
regulation of nucleic acid templated transcription GO:1903506 165 0.019
Mouse
asymmetric cell division GO:0008356 36 0.019
purine nucleoside catabolic process GO:0006152 75 0.019
Human
organic acid metabolic process GO:0006082 47 0.019
secretion GO:0046903 147 0.019
regulation of protein localization GO:0032880 50 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.019
Human
chromosome segregation GO:0007059 180 0.019
Fly
regulation of ras protein signal transduction GO:0046578 41 0.019
Human
proteasomal protein catabolic process GO:0010498 20 0.019
Mouse Fly
cellular macromolecule catabolic process GO:0044265 73 0.019
Mouse Fly
activation of protein kinase activity GO:0032147 11 0.018
carboxylic acid metabolic process GO:0019752 34 0.018
positive regulation of transferase activity GO:0051347 21 0.018
Mouse
cellular macromolecular complex assembly GO:0034622 184 0.018
tissue morphogenesis GO:0048729 65 0.018
regulation of hydrolase activity GO:0051336 45 0.018
Human
positive regulation of signal transduction GO:0009967 40 0.018
Mouse
tissue development GO:0009888 112 0.018
Human Mouse Fly
oxoacid metabolic process GO:0043436 47 0.018
regulation of apoptotic signaling pathway GO:2001233 1 0.018
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.018
rna interference GO:0016246 137 0.018
transcription dna templated GO:0006351 168 0.018
Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.018
Mouse
nitrogen compound transport GO:0071705 49 0.018
negative regulation of response to stimulus GO:0048585 73 0.018
guanosine containing compound catabolic process GO:1901069 48 0.018
Human
regulation of kinase activity GO:0043549 29 0.018
Rat Fly
response to other organism GO:0051707 101 0.018
rho protein signal transduction GO:0007266 2 0.018
organ morphogenesis GO:0009887 67 0.018
Mouse Fly
regulation of organ morphogenesis GO:2000027 4 0.018
regulation of programmed cell death GO:0043067 50 0.018
Human Mouse Rat
tube development GO:0035295 126 0.017
mating behavior GO:0007617 32 0.017
establishment of spindle orientation GO:0051294 34 0.017
purine ribonucleotide catabolic process GO:0009154 75 0.017
Human
positive regulation of protein transport GO:0051222 4 0.017
Human
axonal fasciculation GO:0007413 79 0.017
innate immune response GO:0045087 190 0.017
regulation of axon extension GO:0030516 20 0.017
Mouse
oocyte development GO:0048599 44 0.017
positive regulation of stress activated mapk cascade GO:0032874 3 0.017
regulation of neuron differentiation GO:0045664 40 0.017
Mouse Rat
response to external biotic stimulus GO:0043207 101 0.017
dauer larval development GO:0040024 92 0.017
stress activated mapk cascade GO:0051403 10 0.017
Fly
stress activated protein kinase signaling cascade GO:0031098 10 0.016
Fly
positive regulation of transport GO:0051050 32 0.016
Human Mouse
establishment of protein localization to membrane GO:0090150 3 0.016
cellular nitrogen compound catabolic process GO:0044270 119 0.016
Human
regulation of behavior GO:0050795 97 0.016
actomyosin structure organization GO:0031032 154 0.016
regulation of biosynthetic process GO:0009889 189 0.016
Mouse
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.016
Mouse Fly
positive regulation of stem cell differentiation GO:2000738 1 0.016
Mouse
neuromuscular junction development GO:0007528 2 0.016
Fly
protein modification by small protein conjugation or removal GO:0070647 40 0.016
lipid metabolic process GO:0006629 77 0.016
regulation of nucleoside metabolic process GO:0009118 37 0.016
Human
guanosine containing compound metabolic process GO:1901068 49 0.016
Human
purine nucleoside metabolic process GO:0042278 92 0.016
Human
regulation of meiosis GO:0040020 94 0.015
regulation of meiotic cell cycle GO:0051445 136 0.015
tube formation GO:0035148 2 0.015
negative regulation of cell cycle GO:0045786 53 0.015
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.015
Mouse Fly
cellular response to endogenous stimulus GO:0071495 32 0.015
Human Mouse
nucleoside triphosphate catabolic process GO:0009143 72 0.015
Human
cellular response to growth factor stimulus GO:0071363 18 0.015
response to fibroblast growth factor GO:0071774 5 0.015
myosin filament organization GO:0031033 138 0.015
regulation of hormone secretion GO:0046883 2 0.015
myofibril assembly GO:0030239 154 0.015
regulation of stress activated mapk cascade GO:0032872 5 0.015
Fly
muscle system process GO:0003012 43 0.015
Mouse
defense response to other organism GO:0098542 100 0.015
phagocytosis engulfment GO:0006911 98 0.015
oxidation reduction process GO:0055114 59 0.015
Human
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
purine ribonucleotide metabolic process GO:0009150 95 0.015
Human Mouse
sensory perception GO:0007600 27 0.014
positive regulation of cellular protein catabolic process GO:1903364 3 0.014
Mouse Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
response to endogenous stimulus GO:0009719 33 0.014
Human Mouse
negative regulation of locomotion GO:0040013 21 0.014
oocyte differentiation GO:0009994 45 0.014
regulation of synapse assembly GO:0051963 2 0.014
Fly
epithelial tube morphogenesis GO:0060562 1 0.014
response to biotic stimulus GO:0009607 101 0.014
Human Mouse
microtubule polymerization or depolymerization GO:0031109 22 0.014
regulation of ras gtpase activity GO:0032318 21 0.014
Human
single organism biosynthetic process GO:0044711 91 0.014
Mouse
g protein coupled receptor signaling pathway GO:0007186 46 0.014
Mouse
regulation of protein kinase activity GO:0045859 28 0.014
Rat Fly
myosin filament assembly GO:0031034 138 0.014
ribonucleoside triphosphate metabolic process GO:0009199 87 0.014
Human
regulation of protein import into nucleus GO:0042306 3 0.014
Human
cellular amine metabolic process GO:0044106 15 0.014
calcium mediated signaling GO:0019722 3 0.013
Fly
ribonucleoprotein complex assembly GO:0022618 4 0.013
apoptotic cell clearance GO:0043277 111 0.013
regulation of cell death GO:0010941 65 0.013
Human Mouse Rat
ribonucleotide catabolic process GO:0009261 75 0.013
Human
jnk cascade GO:0007254 8 0.013
Fly
ribonucleotide metabolic process GO:0009259 99 0.013
Human Mouse
positive regulation of protein modification process GO:0031401 29 0.013
Mouse
positive regulation of gene expression GO:0010628 112 0.013
Mouse
modification dependent protein catabolic process GO:0019941 32 0.013
Mouse Fly
regulation of protein ubiquitination GO:0031396 3 0.013
detection of abiotic stimulus GO:0009582 4 0.013
nucleotide catabolic process GO:0009166 77 0.013
Human
regulation of response to wounding GO:1903034 1 0.013
response to heat GO:0009408 50 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
positive regulation of protein metabolic process GO:0051247 45 0.013
Mouse Fly
regulation of cellular localization GO:0060341 42 0.013

gsk-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.051
disease of cellular proliferation DOID:14566 0 0.051
disease of anatomical entity DOID:7 0 0.023
organ system cancer DOID:0050686 0 0.015
gastrointestinal system cancer DOID:3119 0 0.015
disease of metabolism DOID:0014667 0 0.014