Caenorhabditis elegans

106 known processes

mat-2 (CELE_W10C6.1)

Protein MAT-2

mat-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
developmental process involved in reproduction GO:0003006 1165 0.886
embryo development ending in birth or egg hatching GO:0009792 2992 0.554
embryo development GO:0009790 3052 0.469
multicellular organism reproduction GO:0032504 819 0.403
single organism reproductive process GO:0044702 1196 0.397
multicellular organismal reproductive process GO:0048609 815 0.380
organelle organization GO:0006996 783 0.335
cell cycle GO:0007049 526 0.332
regulation of cellular component organization GO:0051128 248 0.327
reproductive structure development GO:0048608 850 0.326
gene expression GO:0010467 412 0.317
meiotic cell cycle GO:0051321 335 0.296
single organism organelle organization GO:1902589 501 0.273
locomotion GO:0040011 1634 0.270
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.262
gonad development GO:0008406 840 0.255
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.248
nucleobase containing compound metabolic process GO:0006139 406 0.243
multi organism reproductive process GO:0044703 867 0.229
organic cyclic compound biosynthetic process GO:1901362 195 0.227
sexual reproduction GO:0019953 546 0.221
organelle fission GO:0048285 363 0.221
negative regulation of biological process GO:0048519 567 0.220
regulation of gene expression GO:0010468 366 0.210
heterocycle biosynthetic process GO:0018130 187 0.193
reproductive system development GO:0061458 850 0.187
germ cell development GO:0007281 351 0.179
regulation of cell cycle process GO:0010564 145 0.177
organic substance biosynthetic process GO:1901576 323 0.170
nucleobase containing compound biosynthetic process GO:0034654 184 0.168
rna biosynthetic process GO:0032774 169 0.163
female gamete generation GO:0007292 254 0.160
oogenesis GO:0048477 229 0.157
regulation of vulval development GO:0040028 248 0.152
cellular response to stress GO:0033554 162 0.152
organ development GO:0048513 1102 0.151
Fly
development of primary sexual characteristics GO:0045137 840 0.151
nucleic acid metabolic process GO:0090304 299 0.148
gamete generation GO:0007276 461 0.146
chromosome organization GO:0051276 104 0.142
cellular component movement GO:0006928 388 0.135
multicellular organismal reproductive behavior GO:0033057 384 0.135
regulation of gene expression epigenetic GO:0040029 163 0.134
regulation of rna biosynthetic process GO:2001141 165 0.126
catabolic process GO:0009056 318 0.125
genitalia development GO:0048806 741 0.122
meiotic cell cycle process GO:1903046 170 0.121
response to abiotic stimulus GO:0009628 152 0.115
cell cycle process GO:0022402 482 0.115
regulation of biosynthetic process GO:0009889 189 0.114
transcription dna templated GO:0006351 168 0.111
biosynthetic process GO:0009058 323 0.110
macromolecular complex subunit organization GO:0043933 320 0.110
regulation of primary metabolic process GO:0080090 292 0.108
body morphogenesis GO:0010171 620 0.106
macromolecule biosynthetic process GO:0009059 250 0.104
macromolecule localization GO:0033036 771 0.102
hermaphrodite genitalia development GO:0040035 734 0.101
nucleobase containing compound catabolic process GO:0034655 114 0.101
inductive cell migration GO:0040039 145 0.098
mitotic cell cycle process GO:1903047 194 0.097
posttranscriptional gene silencing GO:0016441 143 0.097
oviposition GO:0018991 364 0.097
chromosome segregation GO:0007059 180 0.096
cellular biosynthetic process GO:0044249 315 0.096
chromatin organization GO:0006325 32 0.094
purine nucleoside triphosphate catabolic process GO:0009146 72 0.087
negative regulation of metabolic process GO:0009892 240 0.086
regulation of post embryonic development GO:0048580 260 0.084
regulation of cellular biosynthetic process GO:0031326 189 0.081
regulation of multicellular organismal process GO:0051239 726 0.081
post embryonic development GO:0009791 2152 0.080
regulation of nematode larval development GO:0061062 260 0.078
dna metabolic process GO:0006259 74 0.078
cellular macromolecule biosynthetic process GO:0034645 247 0.078
sex differentiation GO:0007548 909 0.077
cellular nitrogen compound biosynthetic process GO:0044271 192 0.075
lipid storage GO:0019915 565 0.073
regulation of macromolecule biosynthetic process GO:0010556 189 0.072
negative regulation of cellular process GO:0048523 239 0.072
ras protein signal transduction GO:0007265 31 0.072
positive regulation of macromolecule metabolic process GO:0010604 149 0.071
multi organism reproductive behavior GO:0044705 387 0.071
maintenance of location GO:0051235 580 0.069
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.067
lipid localization GO:0010876 573 0.066
regulation of macromolecule metabolic process GO:0060255 421 0.066
multicellular organismal aging GO:0010259 812 0.065
rna interference GO:0016246 137 0.064
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.063
organophosphate catabolic process GO:0046434 81 0.063
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.063
response to external stimulus GO:0009605 289 0.062
regulation of metabolic process GO:0019222 478 0.062
protein complex subunit organization GO:0071822 280 0.062
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.062
positive regulation of gene expression GO:0010628 112 0.061
glycosyl compound metabolic process GO:1901657 100 0.061
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.061
positive regulation of metabolic process GO:0009893 187 0.060
regulation of response to stimulus GO:0048583 243 0.060
cell development GO:0048468 696 0.060
positive regulation of nucleic acid templated transcription GO:1903508 102 0.059
apoptotic process GO:0006915 478 0.059
meiotic nuclear division GO:0007126 300 0.058
dna duplex unwinding GO:0032508 3 0.058
chromatin assembly or disassembly GO:0006333 1 0.057
rna metabolic process GO:0016070 228 0.057
proximal distal pattern formation GO:0009954 6 0.057
negative regulation of nematode larval development GO:0061064 208 0.056
localization of cell GO:0051674 313 0.056
positive regulation of cellular metabolic process GO:0031325 178 0.056
negative regulation of gene expression GO:0010629 217 0.056
regulation of multicellular organismal development GO:2000026 317 0.055
transcription from rna polymerase ii promoter GO:0006366 149 0.055
multi multicellular organism process GO:0044706 390 0.055
spindle organization GO:0007051 92 0.054
aromatic compound biosynthetic process GO:0019438 192 0.054
small molecule metabolic process GO:0044281 186 0.053
regulation of transcription dna templated GO:0006355 164 0.053
establishment of organelle localization GO:0051656 123 0.053
behavior GO:0007610 527 0.052
carbohydrate derivative catabolic process GO:1901136 82 0.052
single organism catabolic process GO:0044712 129 0.051
aging GO:0007568 812 0.050
regulation of developmental process GO:0050793 684 0.050
gene silencing by rna GO:0031047 143 0.049
post embryonic organ development GO:0048569 336 0.048
nucleus organization GO:0006997 38 0.048
determination of adult lifespan GO:0008340 812 0.048
regulation of nucleic acid templated transcription GO:1903506 165 0.047
purine nucleotide catabolic process GO:0006195 75 0.046
signaling GO:0023052 401 0.046
cellular response to dna damage stimulus GO:0006974 41 0.046
single organism signaling GO:0044700 401 0.045
multi organism behavior GO:0051705 389 0.045
reproductive behavior GO:0019098 387 0.044
regulation of cellular metabolic process GO:0031323 305 0.044
posttranscriptional regulation of gene expression GO:0010608 166 0.044
negative regulation of macromolecule metabolic process GO:0010605 229 0.043
growth GO:0040007 562 0.043
regulation of rna metabolic process GO:0051252 173 0.043
regulation of cell cycle GO:0051726 194 0.042
purine containing compound metabolic process GO:0072521 95 0.042
pattern specification process GO:0007389 59 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.042
response to organic substance GO:0010033 131 0.041
nucleic acid templated transcription GO:0097659 169 0.041
posttranscriptional gene silencing by rna GO:0035194 143 0.040
nucleotide catabolic process GO:0009166 77 0.039
cellular protein modification process GO:0006464 207 0.039
Human
organic cyclic compound catabolic process GO:1901361 119 0.039
negative regulation of developmental process GO:0051093 227 0.038
ribonucleotide metabolic process GO:0009259 99 0.037
glycosyl compound catabolic process GO:1901658 79 0.036
negative regulation of multicellular organismal process GO:0051241 236 0.036
chromatin remodeling GO:0006338 2 0.036
regulation of biological quality GO:0065008 741 0.036
localization within membrane GO:0051668 2 0.035
positive regulation of transcription dna templated GO:0045893 102 0.034
ribonucleoside triphosphate catabolic process GO:0009203 72 0.034
ribonucleoprotein complex assembly GO:0022618 4 0.032
signal transduction GO:0007165 317 0.032
macromolecular complex assembly GO:0065003 193 0.032
histone modification GO:0016570 30 0.031
purine containing compound catabolic process GO:0072523 75 0.031
endocytosis GO:0006897 819 0.031
purine nucleoside metabolic process GO:0042278 92 0.031
negative regulation of post embryonic development GO:0048581 208 0.031
regulation of growth GO:0040008 409 0.031
epithelial tube morphogenesis GO:0060562 1 0.031
regulation of nitrogen compound metabolic process GO:0051171 222 0.031
nucleoside metabolic process GO:0009116 99 0.030
organophosphate metabolic process GO:0019637 125 0.030
cell division GO:0051301 262 0.030
multicellular organism growth GO:0035264 385 0.029
organonitrogen compound catabolic process GO:1901565 90 0.029
cellular component morphogenesis GO:0032989 318 0.029
nucleoside phosphate metabolic process GO:0006753 108 0.029
negative regulation of gene expression epigenetic GO:0045814 2 0.029
nuclear pore organization GO:0006999 2 0.029
rna localization GO:0006403 3 0.028
centrosomal and pronuclear rotation GO:0035047 6 0.028
cell morphogenesis GO:0000902 163 0.028
dosage compensation GO:0007549 13 0.027
intracellular signal transduction GO:0035556 96 0.027
regulation of mitotic cell cycle GO:0007346 76 0.027
vulval development GO:0040025 333 0.027
regulation of cellular protein metabolic process GO:0032268 75 0.027
organelle assembly GO:0070925 214 0.026
negative regulation of rna metabolic process GO:0051253 53 0.026
dna geometric change GO:0032392 3 0.026
cellular macromolecule localization GO:0070727 75 0.026
organonitrogen compound metabolic process GO:1901564 151 0.026
tube development GO:0035295 126 0.025
regulation of multicellular organism growth GO:0040014 373 0.025
protein metabolic process GO:0019538 422 0.025
ribonucleotide catabolic process GO:0009261 75 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.025
cellular macromolecular complex assembly GO:0034622 184 0.024
meiotic chromosome segregation GO:0045132 139 0.024
cell motility GO:0048870 313 0.024
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.024
gene silencing GO:0016458 143 0.024
ribose phosphate metabolic process GO:0019693 99 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.024
cuticle development GO:0042335 100 0.023
digestive system development GO:0055123 122 0.023
purine ribonucleotide metabolic process GO:0009150 95 0.023
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.022
programmed cell death GO:0012501 500 0.022
cell migration GO:0016477 306 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.022
protein deubiquitination GO:0016579 2 0.022
positive regulation of biosynthetic process GO:0009891 109 0.022
purine ribonucleotide catabolic process GO:0009154 75 0.022
nucleobase containing small molecule metabolic process GO:0055086 115 0.021
nuclear pore distribution GO:0031081 2 0.021
heterocycle catabolic process GO:0046700 119 0.021
ribonucleoside triphosphate metabolic process GO:0009199 87 0.021
purine nucleoside monophosphate metabolic process GO:0009126 43 0.021
cellular catabolic process GO:0044248 199 0.021
nucleotide metabolic process GO:0009117 108 0.021
pigmentation GO:0043473 2 0.021
negative regulation of biosynthetic process GO:0009890 65 0.021
positive regulation of cellular process GO:0048522 332 0.021
regulation of cell communication GO:0010646 176 0.021
positive regulation of rna metabolic process GO:0051254 103 0.021
nucleoside monophosphate metabolic process GO:0009123 46 0.021
organelle localization GO:0051640 127 0.020
ribonucleoside monophosphate metabolic process GO:0009161 45 0.020
nucleoside catabolic process GO:0009164 78 0.020
negative regulation of cellular metabolic process GO:0031324 95 0.020
cellular component biogenesis GO:0044085 297 0.020
organic acid metabolic process GO:0006082 47 0.020
pharyngeal pumping GO:0043050 58 0.019
negative regulation of vulval development GO:0040027 206 0.019
chromatin assembly GO:0031497 1 0.019
dna conformation change GO:0071103 11 0.019
vesicle mediated transport GO:0016192 852 0.019
macromolecule modification GO:0043412 218 0.019
Human
response to chemical GO:0042221 356 0.019
response to wounding GO:0009611 4 0.018
cellular nitrogen compound catabolic process GO:0044270 119 0.018
purine ribonucleoside metabolic process GO:0046128 92 0.018
neurogenesis GO:0022008 236 0.018
Fly
atp metabolic process GO:0046034 42 0.018
ion transmembrane transport GO:0034220 91 0.017
purine nucleotide metabolic process GO:0006163 95 0.017
organic substance catabolic process GO:1901575 294 0.017
nucleoside phosphate catabolic process GO:1901292 77 0.017
purine nucleoside monophosphate catabolic process GO:0009128 28 0.017
nucleoside triphosphate catabolic process GO:0009143 72 0.017
regulation of meiotic cell cycle GO:0051445 136 0.017
phosphorus metabolic process GO:0006793 232 0.017
aromatic compound catabolic process GO:0019439 116 0.016
regulation of cell fate specification GO:0042659 22 0.016
rna dependent dna replication GO:0006278 3 0.016
transmembrane transport GO:0055085 110 0.016
anatomical structure formation involved in morphogenesis GO:0048646 250 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.016
cell projection organization GO:0030030 231 0.016
chromatin modification GO:0016568 32 0.016
regulation of intracellular signal transduction GO:1902531 77 0.016
receptor mediated endocytosis GO:0006898 715 0.016
positive regulation of multicellular organism growth GO:0040018 352 0.016
molting cycle GO:0042303 281 0.015
cellular component assembly GO:0022607 293 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
cellular protein localization GO:0034613 75 0.015
mitotic spindle organization GO:0007052 81 0.014
positive regulation of cellular component organization GO:0051130 34 0.014
developmental growth GO:0048589 412 0.014
cellular protein metabolic process GO:0044267 279 0.014
dosage compensation by hypoactivation of x chromosome GO:0042464 11 0.014
organic substance transport GO:0071702 113 0.014
purine ribonucleoside catabolic process GO:0046130 75 0.014
regulation of protein metabolic process GO:0051246 81 0.014
microtubule based process GO:0007017 182 0.014
internal peptidyl lysine acetylation GO:0018393 3 0.014
response to inorganic substance GO:0010035 50 0.013
positive regulation of nucleoside metabolic process GO:0045979 28 0.013
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.013
protein localization GO:0008104 205 0.013
nervous system development GO:0007399 253 0.013
Fly
muscle structure development GO:0061061 191 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.013
anterior posterior pattern specification GO:0009952 27 0.013
cellular protein complex localization GO:0034629 3 0.013
carbohydrate derivative metabolic process GO:1901135 141 0.012
eating behavior GO:0042755 59 0.012
establishment of localization GO:0051234 1171 0.012
protein complex biogenesis GO:0070271 186 0.012
rrna processing GO:0006364 3 0.012
cytoskeleton organization GO:0007010 339 0.012
regulation of organelle organization GO:0033043 164 0.012
regulation of cell division GO:0051302 142 0.012
regulation of chromatin organization GO:1902275 2 0.012
regulation of small gtpase mediated signal transduction GO:0051056 41 0.012
death GO:0016265 547 0.011
actomyosin structure organization GO:0031032 154 0.011
positive regulation of multicellular organismal process GO:0051240 417 0.011
dna repair GO:0006281 23 0.011
pronuclear migration GO:0035046 51 0.011
embryonic body morphogenesis GO:0010172 49 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
purine nucleoside catabolic process GO:0006152 75 0.011
positive regulation of growth GO:0045927 369 0.011
regulation of purine nucleotide metabolic process GO:1900542 37 0.011
phosphate containing compound metabolic process GO:0006796 232 0.011
protein complex localization GO:0031503 3 0.011
actin filament based movement GO:0030048 4 0.010
protein complex assembly GO:0006461 186 0.010
cellular ketone metabolic process GO:0042180 14 0.010
germ line sex determination GO:0018992 51 0.010
regulation of protein targeting GO:1903533 3 0.010
dna templated transcription initiation GO:0006352 3 0.010

mat-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.038
cancer DOID:162 0 0.038
disease of cellular proliferation DOID:14566 0 0.038
organ system cancer DOID:0050686 0 0.038
reproductive organ cancer DOID:193 0 0.020
female reproductive organ cancer DOID:120 0 0.020
large intestine cancer DOID:5672 0 0.015
intestinal cancer DOID:10155 0 0.015