Caenorhabditis elegans

90 known processes

let-754 (CELE_C29E4.8)

Protein LET-754

let-754 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.726
receptor mediated endocytosis GO:0006898 715 0.637
embryo development GO:0009790 3052 0.550
vesicle mediated transport GO:0016192 852 0.528
establishment of localization GO:0051234 1171 0.517
sex differentiation GO:0007548 909 0.494
gonad development GO:0008406 840 0.459
endocytosis GO:0006897 819 0.451
post embryonic development GO:0009791 2152 0.369
multicellular organism reproduction GO:0032504 819 0.345
development of primary sexual characteristics GO:0045137 840 0.326
transport GO:0006810 1093 0.305
regulation of developmental process GO:0050793 684 0.255
organ development GO:0048513 1102 0.248
pronuclear migration GO:0035046 51 0.246
organelle organization GO:0006996 783 0.242
death GO:0016265 547 0.229
locomotion GO:0040011 1634 0.227
developmental process involved in reproduction GO:0003006 1165 0.211
sexual reproduction GO:0019953 546 0.208
single organism reproductive process GO:0044702 1196 0.199
single fertilization GO:0007338 61 0.174
determination of adult lifespan GO:0008340 812 0.166
cell migration GO:0016477 306 0.158
cellular localization GO:0051641 360 0.155
regulation of multicellular organism growth GO:0040014 373 0.148
multicellular organismal aging GO:0010259 812 0.148
single organism transport GO:0044765 447 0.147
aging GO:0007568 812 0.145
positive regulation of multicellular organismal process GO:0051240 417 0.136
establishment of organelle localization GO:0051656 123 0.136
developmental growth GO:0048589 412 0.135
reproductive system development GO:0061458 850 0.135
single organism localization GO:1902578 518 0.130
multicellular organismal reproductive process GO:0048609 815 0.124
cell development GO:0048468 696 0.120
establishment of nucleus localization GO:0040023 55 0.116
macromolecule localization GO:0033036 771 0.100
regulation of multicellular organismal process GO:0051239 726 0.096
positive regulation of developmental process GO:0051094 408 0.091
multi organism reproductive process GO:0044703 867 0.091
secretion by cell GO:0032940 138 0.087
apoptotic process GO:0006915 478 0.087
muscle cell differentiation GO:0042692 171 0.086
regulation of biological quality GO:0065008 741 0.085
body morphogenesis GO:0010171 620 0.076
cell death GO:0008219 547 0.076
muscle structure development GO:0061061 191 0.076
purine ribonucleoside metabolic process GO:0046128 92 0.075
reproductive structure development GO:0048608 850 0.074
programmed cell death GO:0012501 500 0.073
secretion GO:0046903 147 0.073
maintenance of location GO:0051235 580 0.071
organelle localization GO:0051640 127 0.068
gamete generation GO:0007276 461 0.067
cell motility GO:0048870 313 0.067
lipid localization GO:0010876 573 0.066
cellular component assembly GO:0022607 293 0.063
lipid storage GO:0019915 565 0.063
regulation of developmental growth GO:0048638 389 0.061
hermaphrodite genitalia development GO:0040035 734 0.058
positive regulation of multicellular organism growth GO:0040018 352 0.057
protein complex subunit organization GO:0071822 280 0.057
multicellular organism growth GO:0035264 385 0.057
regulation of metabolic process GO:0019222 478 0.057
cellular component movement GO:0006928 388 0.056
genitalia development GO:0048806 741 0.056
organic substance catabolic process GO:1901575 294 0.056
positive regulation of developmental growth GO:0048639 354 0.055
molting cycle GO:0042303 281 0.054
muscle cell development GO:0055001 158 0.053
single organism organelle organization GO:1902589 501 0.053
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.053
localization of cell GO:0051674 313 0.053
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.052
single organism signaling GO:0044700 401 0.052
regulation of localization GO:0032879 194 0.052
establishment of localization in cell GO:0051649 318 0.050
protein metabolic process GO:0019538 422 0.049
female gamete generation GO:0007292 254 0.046
behavior GO:0007610 527 0.045
spermatogenesis GO:0007283 41 0.044
nuclear migration GO:0007097 54 0.042
striated muscle cell differentiation GO:0051146 158 0.042
multicellular organismal reproductive behavior GO:0033057 384 0.041
growth GO:0040007 562 0.041
germ cell development GO:0007281 351 0.040
small molecule metabolic process GO:0044281 186 0.040
defense response to bacterium GO:0042742 86 0.040
tissue development GO:0009888 112 0.039
striated muscle cell development GO:0055002 157 0.038
nervous system development GO:0007399 253 0.038
macromolecular complex subunit organization GO:0043933 320 0.037
response to wounding GO:0009611 4 0.037
protein complex assembly GO:0006461 186 0.037
phosphorus metabolic process GO:0006793 232 0.036
purine containing compound metabolic process GO:0072521 95 0.035
innate immune response GO:0045087 190 0.034
cellular component morphogenesis GO:0032989 318 0.034
cellular protein complex assembly GO:0043623 178 0.033
regulation of growth GO:0040008 409 0.033
transmembrane transport GO:0055085 110 0.033
response to chemical GO:0042221 356 0.032
nucleoside phosphate metabolic process GO:0006753 108 0.032
positive regulation of growth GO:0045927 369 0.031
organonitrogen compound metabolic process GO:1901564 151 0.031
regulation of response to stimulus GO:0048583 243 0.030
actin cytoskeleton organization GO:0030036 184 0.030
biosynthetic process GO:0009058 323 0.030
cellular component biogenesis GO:0044085 297 0.030
macromolecular complex assembly GO:0065003 193 0.030
regulation of macromolecule metabolic process GO:0060255 421 0.030
striated muscle myosin thick filament assembly GO:0071688 138 0.029
macromolecule biosynthetic process GO:0009059 250 0.029
cellular component assembly involved in morphogenesis GO:0010927 183 0.029
negative regulation of biological process GO:0048519 567 0.029
protein complex biogenesis GO:0070271 186 0.028
nucleoside metabolic process GO:0009116 99 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.027
defense response GO:0006952 296 0.026
carbohydrate derivative metabolic process GO:1901135 141 0.026
muscle tissue development GO:0060537 1 0.026
regulation of gene expression GO:0010468 366 0.026
oxoacid metabolic process GO:0043436 47 0.025
regulation of cell differentiation GO:0045595 81 0.025
oxidative phosphorylation GO:0006119 11 0.025
actomyosin structure organization GO:0031032 154 0.025
cellular macromolecular complex assembly GO:0034622 184 0.024
protein catabolic process GO:0030163 162 0.024
posttranscriptional gene silencing by rna GO:0035194 143 0.024
multi organism reproductive behavior GO:0044705 387 0.024
detection of external stimulus GO:0009581 4 0.023
phosphate containing compound metabolic process GO:0006796 232 0.023
oogenesis GO:0048477 229 0.023
ribonucleoside monophosphate metabolic process GO:0009161 45 0.023
organelle assembly GO:0070925 214 0.022
cellular biosynthetic process GO:0044249 315 0.022
purine ribonucleotide metabolic process GO:0009150 95 0.022
cellular respiration GO:0045333 9 0.021
negative regulation of gene expression GO:0010629 217 0.021
glycosyl compound metabolic process GO:1901657 100 0.021
system process GO:0003008 136 0.021
signal transduction GO:0007165 317 0.020
oxidation reduction process GO:0055114 59 0.020
nucleoside triphosphate metabolic process GO:0009141 87 0.020
response to external stimulus GO:0009605 289 0.020
nucleobase containing compound metabolic process GO:0006139 406 0.020
gene expression GO:0010467 412 0.019
ribonucleoside metabolic process GO:0009119 98 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
mitochondrion organization GO:0007005 20 0.019
gene silencing by rna GO:0031047 143 0.019
rna interference GO:0016246 137 0.019
oviposition GO:0018991 364 0.019
phosphorylation GO:0016310 116 0.018
nucleotide metabolic process GO:0009117 108 0.018
digestive system development GO:0055123 122 0.018
cellular protein metabolic process GO:0044267 279 0.018
atp metabolic process GO:0046034 42 0.018
multi multicellular organism process GO:0044706 390 0.018
multi organism behavior GO:0051705 389 0.017
response to external biotic stimulus GO:0043207 101 0.017
myosin filament assembly GO:0031034 138 0.017
fertilization GO:0009566 63 0.017
organic acid metabolic process GO:0006082 47 0.017
negative regulation of macromolecule metabolic process GO:0010605 229 0.017
nucleoside monophosphate metabolic process GO:0009123 46 0.017
myofibril assembly GO:0030239 154 0.017
cytoskeleton organization GO:0007010 339 0.016
catabolic process GO:0009056 318 0.016
ion transport GO:0006811 113 0.016
myosin filament organization GO:0031033 138 0.016
generation of neurons GO:0048699 235 0.016
male gamete generation GO:0048232 41 0.015
purine nucleoside triphosphate metabolic process GO:0009144 87 0.015
regulation of gene expression epigenetic GO:0040029 163 0.015
purine nucleotide metabolic process GO:0006163 95 0.015
digestive tract development GO:0048565 122 0.015
organophosphate metabolic process GO:0019637 125 0.015
reproductive behavior GO:0019098 387 0.014
tube development GO:0035295 126 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
macromolecule catabolic process GO:0009057 202 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
epithelium development GO:0060429 68 0.014
inductive cell migration GO:0040039 145 0.014
eating behavior GO:0042755 59 0.014
negative regulation of developmental process GO:0051093 227 0.014
organ morphogenesis GO:0009887 67 0.014
immune response GO:0006955 192 0.014
ion transmembrane transport GO:0034220 91 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
regulation of cellular metabolic process GO:0031323 305 0.013
regulation of locomotion GO:0040012 161 0.012
nucleus localization GO:0051647 55 0.012
purine nucleoside metabolic process GO:0042278 92 0.012
neurogenesis GO:0022008 236 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
regeneration GO:0031099 4 0.012
actin filament based process GO:0030029 191 0.012
macromolecule modification GO:0043412 218 0.012
regulation of gene silencing GO:0060968 3 0.011
gene silencing GO:0016458 143 0.011
response to abiotic stimulus GO:0009628 152 0.011
signaling GO:0023052 401 0.011
regulation of multicellular organismal development GO:2000026 317 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
single organism biosynthetic process GO:0044711 91 0.011
response to other organism GO:0051707 101 0.011
regulation of cell motility GO:2000145 57 0.010
ribonucleoside triphosphate catabolic process GO:0009203 72 0.010

let-754 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
disease of metabolism DOID:0014667 0 0.018
disease of anatomical entity DOID:7 0 0.016
Human
organ system cancer DOID:0050686 0 0.011