Caenorhabditis elegans

60 known processes

aph-1 (CELE_VF36H2L.1)

Protein APH-1

aph-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.604
negative regulation of biological process GO:0048519 567 0.464
locomotion GO:0040011 1634 0.296
organ development GO:0048513 1102 0.270
Mouse
single organism localization GO:1902578 518 0.245
embryo development GO:0009790 3052 0.224
reproductive structure development GO:0048608 850 0.183
endocytosis GO:0006897 819 0.140
macromolecular complex subunit organization GO:0043933 320 0.138
determination of adult lifespan GO:0008340 812 0.138
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.134
signaling GO:0023052 401 0.123
cell migration GO:0016477 306 0.116
reproductive system development GO:0061458 850 0.112
regulation of biological quality GO:0065008 741 0.110
growth GO:0040007 562 0.107
multicellular organismal reproductive process GO:0048609 815 0.104
multicellular organismal aging GO:0010259 812 0.104
aging GO:0007568 812 0.096
head development GO:0060322 1 0.094
organic cyclic compound biosynthetic process GO:1901362 195 0.094
sex differentiation GO:0007548 909 0.093
cell motility GO:0048870 313 0.087
negative regulation of developmental process GO:0051093 227 0.084
multicellular organism reproduction GO:0032504 819 0.083
single organism reproductive process GO:0044702 1196 0.082
gene expression GO:0010467 412 0.080
Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.078
transport GO:0006810 1093 0.075
regulation of gene expression GO:0010468 366 0.073
multicellular organism growth GO:0035264 385 0.067
cellular component movement GO:0006928 388 0.062
neuron differentiation GO:0030182 217 0.062
single organism signaling GO:0044700 401 0.060
positive regulation of cellular metabolic process GO:0031325 178 0.058
macromolecule localization GO:0033036 771 0.057
vesicle mediated transport GO:0016192 852 0.056
developmental process involved in reproduction GO:0003006 1165 0.054
nucleobase containing compound metabolic process GO:0006139 406 0.054
single organism transport GO:0044765 447 0.053
regulation of nematode larval development GO:0061062 260 0.053
neuron projection development GO:0031175 187 0.052
maintenance of location GO:0051235 580 0.052
lipid storage GO:0019915 565 0.052
regulation of rna biosynthetic process GO:2001141 165 0.052
cell development GO:0048468 696 0.051
biosynthetic process GO:0009058 323 0.051
protein metabolic process GO:0019538 422 0.051
Mouse
regulation of growth GO:0040008 409 0.050
regulation of cellular component organization GO:0051128 248 0.048
lipid localization GO:0010876 573 0.046
development of primary sexual characteristics GO:0045137 840 0.045
signal transduction GO:0007165 317 0.045
cellular biosynthetic process GO:0044249 315 0.045
small molecule metabolic process GO:0044281 186 0.045
regulation of vulval development GO:0040028 248 0.044
phosphate containing compound metabolic process GO:0006796 232 0.044
regulation of multicellular organismal process GO:0051239 726 0.044
negative regulation of post embryonic development GO:0048581 208 0.042
gonad development GO:0008406 840 0.042
response to external stimulus GO:0009605 289 0.041
regulation of cell cycle GO:0051726 194 0.041
generation of neurons GO:0048699 235 0.039
cellular component assembly GO:0022607 293 0.038
regulation of developmental growth GO:0048638 389 0.036
regulation of signaling GO:0023051 172 0.036
organophosphate metabolic process GO:0019637 125 0.035
response to chemical GO:0042221 356 0.033
aromatic compound biosynthetic process GO:0019438 192 0.032
positive regulation of biosynthetic process GO:0009891 109 0.032
cellular protein modification process GO:0006464 207 0.032
nervous system development GO:0007399 253 0.032
cell morphogenesis involved in differentiation GO:0000904 112 0.031
hermaphrodite genitalia development GO:0040035 734 0.031
vulval development GO:0040025 333 0.031
organelle fission GO:0048285 363 0.031
regulation of nitrogen compound metabolic process GO:0051171 222 0.031
negative regulation of multicellular organismal process GO:0051241 236 0.031
receptor mediated endocytosis GO:0006898 715 0.030
regulation of developmental process GO:0050793 684 0.030
regulation of cell communication GO:0010646 176 0.029
gamete generation GO:0007276 461 0.029
organic substance biosynthetic process GO:1901576 323 0.029
sexual reproduction GO:0019953 546 0.028
post embryonic organ development GO:0048569 336 0.028
negative regulation of macromolecule metabolic process GO:0010605 229 0.028
regulation of transcription dna templated GO:0006355 164 0.028
regulation of macromolecule metabolic process GO:0060255 421 0.027
phagocytosis GO:0006909 115 0.027
apoptotic cell clearance GO:0043277 111 0.027
negative regulation of cellular process GO:0048523 239 0.027
positive regulation of transcription dna templated GO:0045893 102 0.027
nucleoside phosphate metabolic process GO:0006753 108 0.027
purine nucleoside metabolic process GO:0042278 92 0.027
macromolecule modification GO:0043412 218 0.026
negative regulation of nematode larval development GO:0061064 208 0.026
behavior GO:0007610 527 0.026
small gtpase mediated signal transduction GO:0007264 32 0.026
establishment of localization in cell GO:0051649 318 0.026
taxis GO:0042330 128 0.025
response to organic substance GO:0010033 131 0.025
secretion GO:0046903 147 0.025
macromolecule biosynthetic process GO:0009059 250 0.025
meiotic nuclear division GO:0007126 300 0.024
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.024
negative regulation of metabolic process GO:0009892 240 0.024
cell cycle process GO:0022402 482 0.023
single organism organelle organization GO:1902589 501 0.023
localization of cell GO:0051674 313 0.023
genitalia development GO:0048806 741 0.023
oxoacid metabolic process GO:0043436 47 0.022
positive regulation of multicellular organismal process GO:0051240 417 0.022
cellular macromolecule biosynthetic process GO:0034645 247 0.022
collagen and cuticulin based cuticle development GO:0040002 99 0.022
chemotaxis GO:0006935 120 0.021
multi organism behavior GO:0051705 389 0.021
developmental growth GO:0048589 412 0.021
positive regulation of multicellular organism growth GO:0040018 352 0.021
cell projection morphogenesis GO:0048858 148 0.021
posttranscriptional regulation of gene expression GO:0010608 166 0.021
organelle organization GO:0006996 783 0.020
positive regulation of developmental process GO:0051094 408 0.020
organonitrogen compound catabolic process GO:1901565 90 0.020
regulation of multicellular organismal development GO:2000026 317 0.020
regulation of post embryonic development GO:0048580 260 0.020
negative regulation of gene expression GO:0010629 217 0.019
cell cycle GO:0007049 526 0.019
regulation of molecular function GO:0065009 89 0.019
axonogenesis GO:0007409 102 0.019
meiotic cell cycle GO:0051321 335 0.019
neuron projection guidance GO:0097485 82 0.019
regulation of nucleotide catabolic process GO:0030811 35 0.019
transmembrane transport GO:0055085 110 0.018
multi multicellular organism process GO:0044706 390 0.018
tissue morphogenesis GO:0048729 65 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.018
positive regulation of rna metabolic process GO:0051254 103 0.018
negative regulation of cellular metabolic process GO:0031324 95 0.018
neuron development GO:0048666 199 0.018
regulation of multicellular organism growth GO:0040014 373 0.017
establishment of localization GO:0051234 1171 0.017
regeneration GO:0031099 4 0.017
cellular component morphogenesis GO:0032989 318 0.017
cytoskeleton organization GO:0007010 339 0.017
regulation of metabolic process GO:0019222 478 0.017
regulation of primary metabolic process GO:0080090 292 0.017
multi organism reproductive process GO:0044703 867 0.017
regulation of cellular metabolic process GO:0031323 305 0.017
cell projection organization GO:0030030 231 0.017
intracellular signal transduction GO:0035556 96 0.016
positive regulation of epithelial cell proliferation GO:0050679 1 0.016
ribonucleoside triphosphate catabolic process GO:0009203 72 0.016
cellular nitrogen compound biosynthetic process GO:0044271 192 0.016
neurogenesis GO:0022008 236 0.016
single organism biosynthetic process GO:0044711 91 0.016
oviposition GO:0018991 364 0.016
purine nucleoside triphosphate catabolic process GO:0009146 72 0.016
posttranscriptional gene silencing by rna GO:0035194 143 0.016
multi organism reproductive behavior GO:0044705 387 0.016
regulation of cell size GO:0008361 30 0.016
regulation of catalytic activity GO:0050790 78 0.015
regulation of gene expression epigenetic GO:0040029 163 0.015
gtp catabolic process GO:0006184 46 0.015
organonitrogen compound metabolic process GO:1901564 151 0.015
body morphogenesis GO:0010171 620 0.015
positive regulation of developmental growth GO:0048639 354 0.015
purine ribonucleotide catabolic process GO:0009154 75 0.015
phagocytosis engulfment GO:0006911 98 0.015
organic substance transport GO:0071702 113 0.015
positive regulation of growth GO:0045927 369 0.014
regulation of localization GO:0032879 194 0.014
axon development GO:0061564 163 0.014
macromolecular complex assembly GO:0065003 193 0.014
engulfment of apoptotic cell GO:0043652 94 0.014
regulation of phosphate metabolic process GO:0019220 81 0.014
gene silencing GO:0016458 143 0.014
response to wounding GO:0009611 4 0.014
positive regulation of gene expression GO:0010628 112 0.014
ras protein signal transduction GO:0007265 31 0.014
rna biosynthetic process GO:0032774 169 0.014
intracellular transport GO:0046907 77 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.013
germ cell development GO:0007281 351 0.013
cellular response to stress GO:0033554 162 0.013
nucleobase containing compound biosynthetic process GO:0034654 184 0.013
positive regulation of cellular biosynthetic process GO:0031328 109 0.013
reproductive behavior GO:0019098 387 0.013
rna interference GO:0016246 137 0.013
cell substrate adhesion GO:0031589 1 0.013
nucleic acid metabolic process GO:0090304 299 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
regulation of nuclear division GO:0051783 115 0.013
organelle localization GO:0051640 127 0.013
secretion by cell GO:0032940 138 0.013
cellular component biogenesis GO:0044085 297 0.012
carbohydrate derivative metabolic process GO:1901135 141 0.012
cellular macromolecular complex assembly GO:0034622 184 0.012
positive regulation of response to stimulus GO:0048584 55 0.012
regulation of response to stimulus GO:0048583 243 0.012
multicellular organismal reproductive behavior GO:0033057 384 0.012
internal protein amino acid acetylation GO:0006475 3 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
negative regulation of gene expression epigenetic GO:0045814 2 0.012
transcription dna templated GO:0006351 168 0.012
epithelium development GO:0060429 68 0.011
internal peptidyl lysine acetylation GO:0018393 3 0.011
establishment of organelle localization GO:0051656 123 0.011
axon guidance GO:0007411 82 0.011
cellular localization GO:0051641 360 0.011
regulation of meiotic cell cycle GO:0051445 136 0.011
nucleoside metabolic process GO:0009116 99 0.011
cell surface receptor signaling pathway GO:0007166 149 0.011
programmed cell death GO:0012501 500 0.011
guanosine containing compound metabolic process GO:1901068 49 0.011
guanosine containing compound catabolic process GO:1901069 48 0.011
response to abiotic stimulus GO:0009628 152 0.011
neuromuscular junction development GO:0007528 2 0.011
cellular protein metabolic process GO:0044267 279 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.011
inductive cell migration GO:0040039 145 0.010
sensory organ morphogenesis GO:0090596 2 0.010

aph-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org