Caenorhabditis elegans

10 known processes

npp-22 (CELE_B0240.4)

Protein NPP-22

npp-22 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.909
embryo development ending in birth or egg hatching GO:0009792 2992 0.845
developmental process involved in reproduction GO:0003006 1165 0.751
sexual reproduction GO:0019953 546 0.663
Worm
hermaphrodite genitalia development GO:0040035 734 0.651
post embryonic development GO:0009791 2152 0.648
multicellular organismal reproductive process GO:0048609 815 0.614
gonad development GO:0008406 840 0.608
reproductive system development GO:0061458 850 0.600
establishment of localization GO:0051234 1171 0.592
development of primary sexual characteristics GO:0045137 840 0.494
regulation of cell differentiation GO:0045595 81 0.477
sex differentiation GO:0007548 909 0.462
transport GO:0006810 1093 0.461
nucleobase containing compound metabolic process GO:0006139 406 0.450
apoptotic process GO:0006915 478 0.442
positive regulation of rna biosynthetic process GO:1902680 102 0.424
programmed cell death GO:0012501 500 0.387
gamete generation GO:0007276 461 0.382
regulation of multicellular organismal process GO:0051239 726 0.374
cellular nitrogen compound biosynthetic process GO:0044271 192 0.373
single organism reproductive process GO:0044702 1196 0.368
Worm
vesicle mediated transport GO:0016192 852 0.367
regulation of rna metabolic process GO:0051252 173 0.366
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.358
cell cycle process GO:0022402 482 0.351
organ development GO:0048513 1102 0.337
genitalia development GO:0048806 741 0.334
receptor mediated endocytosis GO:0006898 715 0.326
endocytosis GO:0006897 819 0.323
macromolecule modification GO:0043412 218 0.315
multicellular organism reproduction GO:0032504 819 0.311
locomotion GO:0040011 1634 0.304
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.292
reproductive structure development GO:0048608 850 0.284
macromolecule catabolic process GO:0009057 202 0.284
regulation of developmental process GO:0050793 684 0.281
positive regulation of metabolic process GO:0009893 187 0.268
organelle organization GO:0006996 783 0.260
positive regulation of cellular process GO:0048522 332 0.255
growth GO:0040007 562 0.235
nucleobase containing compound biosynthetic process GO:0034654 184 0.231
nucleic acid metabolic process GO:0090304 299 0.221
catabolic process GO:0009056 318 0.214
response to external stimulus GO:0009605 289 0.206
transcription from rna polymerase ii promoter GO:0006366 149 0.200
regulation of metabolic process GO:0019222 478 0.199
cell development GO:0048468 696 0.198
regulation of signal transduction GO:0009966 135 0.195
positive regulation of macromolecule metabolic process GO:0010604 149 0.193
germ cell development GO:0007281 351 0.192
regulation of macromolecule metabolic process GO:0060255 421 0.189
developmental growth GO:0048589 412 0.186
mitotic cell cycle process GO:1903047 194 0.182
negative regulation of biological process GO:0048519 567 0.181
cellular catabolic process GO:0044248 199 0.180
single organism organelle organization GO:1902589 501 0.180
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.179
regulation of meiotic cell cycle GO:0051445 136 0.178
signal transduction GO:0007165 317 0.177
cell death GO:0008219 547 0.175
rna metabolic process GO:0016070 228 0.166
regulation of rna biosynthetic process GO:2001141 165 0.165
signaling GO:0023052 401 0.164
regulation of nucleic acid templated transcription GO:1903506 165 0.164
cellular response to stress GO:0033554 162 0.163
cell migration GO:0016477 306 0.157
regulation of primary metabolic process GO:0080090 292 0.156
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.153
positive regulation of cellular biosynthetic process GO:0031328 109 0.152
female gamete generation GO:0007292 254 0.149
regulation of multicellular organismal development GO:2000026 317 0.149
organic cyclic compound biosynthetic process GO:1901362 195 0.145
regulation of transcription dna templated GO:0006355 164 0.143
intracellular signal transduction GO:0035556 96 0.143
positive regulation of multicellular organismal process GO:0051240 417 0.139
cellular protein modification process GO:0006464 207 0.134
regulation of gene expression GO:0010468 366 0.133
protein metabolic process GO:0019538 422 0.133
organelle fission GO:0048285 363 0.133
nucleic acid templated transcription GO:0097659 169 0.128
protein modification process GO:0036211 207 0.128
regulation of growth GO:0040008 409 0.128
negative regulation of transcription dna templated GO:0045892 53 0.127
phosphorylation GO:0016310 116 0.125
positive regulation of developmental process GO:0051094 408 0.125
cytoskeleton organization GO:0007010 339 0.125
localization of cell GO:0051674 313 0.123
macromolecular complex subunit organization GO:0043933 320 0.121
cellular localization GO:0051641 360 0.119
aromatic compound biosynthetic process GO:0019438 192 0.119
multi organism reproductive process GO:0044703 867 0.119
Worm
protein catabolic process GO:0030163 162 0.118
single organism signaling GO:0044700 401 0.116
response to abiotic stimulus GO:0009628 152 0.116
cell cycle GO:0007049 526 0.116
rna biosynthetic process GO:0032774 169 0.115
positive regulation of rna metabolic process GO:0051254 103 0.113
death GO:0016265 547 0.111
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.109
cellular component movement GO:0006928 388 0.102
negative regulation of cellular process GO:0048523 239 0.100
positive regulation of cellular metabolic process GO:0031325 178 0.100
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.099
positive regulation of growth GO:0045927 369 0.098
phosphorus metabolic process GO:0006793 232 0.098
regulation of macromolecule biosynthetic process GO:0010556 189 0.097
single organism localization GO:1902578 518 0.094
response to wounding GO:0009611 4 0.093
embryonic morphogenesis GO:0048598 152 0.093
immune response GO:0006955 192 0.092
cellular response to organic substance GO:0071310 119 0.090
transcription dna templated GO:0006351 168 0.089
negative regulation of nucleic acid templated transcription GO:1903507 53 0.084
regulation of cell cycle process GO:0010564 145 0.084
response to chemical GO:0042221 356 0.083
oocyte development GO:0048599 44 0.083
head development GO:0060322 1 0.082
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.082
membrane organization GO:0061024 135 0.081
single organism cellular localization GO:1902580 72 0.080
determination of adult lifespan GO:0008340 812 0.079
body morphogenesis GO:0010171 620 0.079
proteolysis GO:0006508 61 0.076
regulation of biological quality GO:0065008 741 0.076
cellular biosynthetic process GO:0044249 315 0.075
aging GO:0007568 812 0.074
digestive system development GO:0055123 122 0.074
positive regulation of biosynthetic process GO:0009891 109 0.074
cell motility GO:0048870 313 0.073
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.073
gene expression GO:0010467 412 0.073
macromolecule localization GO:0033036 771 0.071
defense response to other organism GO:0098542 100 0.070
cell division GO:0051301 262 0.070
regulation of neurogenesis GO:0050767 40 0.069
negative regulation of macromolecule metabolic process GO:0010605 229 0.068
positive regulation of transcription dna templated GO:0045893 102 0.068
organic substance biosynthetic process GO:1901576 323 0.067
positive regulation of developmental growth GO:0048639 354 0.066
meiotic cell cycle process GO:1903046 170 0.066
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.066
heterocycle biosynthetic process GO:0018130 187 0.066
regulation of developmental growth GO:0048638 389 0.065
negative regulation of gene expression GO:0010629 217 0.064
positive regulation of neurogenesis GO:0050769 4 0.064
regulation of multicellular organism growth GO:0040014 373 0.063
lipid localization GO:0010876 573 0.063
nucleobase containing compound catabolic process GO:0034655 114 0.063
defense response GO:0006952 296 0.063
mitotic nuclear division GO:0007067 89 0.063
meiotic cell cycle GO:0051321 335 0.062
modification dependent protein catabolic process GO:0019941 32 0.062
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.062
lipid storage GO:0019915 565 0.061
maintenance of location GO:0051235 580 0.061
oocyte differentiation GO:0009994 45 0.061
multicellular organismal aging GO:0010259 812 0.059
nucleoside triphosphate metabolic process GO:0009141 87 0.059
regulation of cellular component organization GO:0051128 248 0.059
cellular component morphogenesis GO:0032989 318 0.059
regulation of cell development GO:0060284 49 0.057
regulation of cell communication GO:0010646 176 0.057
biosynthetic process GO:0009058 323 0.057
multicellular organism growth GO:0035264 385 0.056
positive regulation of multicellular organism growth GO:0040018 352 0.056
nervous system development GO:0007399 253 0.056
response to organic substance GO:0010033 131 0.056
cellular component biogenesis GO:0044085 297 0.054
oviposition GO:0018991 364 0.054
regulation of phosphorus metabolic process GO:0051174 81 0.054
meiotic nuclear division GO:0007126 300 0.052
regulation of catabolic process GO:0009894 57 0.052
cellular nitrogen compound catabolic process GO:0044270 119 0.052
digestive tract development GO:0048565 122 0.052
cellular macromolecule catabolic process GO:0044265 73 0.051
regulation of response to stimulus GO:0048583 243 0.050
response to external biotic stimulus GO:0043207 101 0.050
homeostatic process GO:0042592 51 0.049
macromolecule biosynthetic process GO:0009059 250 0.049
positive regulation of gene expression GO:0010628 112 0.049
gene silencing GO:0016458 143 0.048
spermatogenesis GO:0007283 41 0.048
regulation of phosphorylation GO:0042325 45 0.048
neurological system process GO:0050877 53 0.048
regulation of localization GO:0032879 194 0.047
muscle structure development GO:0061061 191 0.046
cellular protein metabolic process GO:0044267 279 0.046
pronuclear migration GO:0035046 51 0.045
regulation of biosynthetic process GO:0009889 189 0.045
organic substance catabolic process GO:1901575 294 0.044
negative regulation of cellular biosynthetic process GO:0031327 65 0.044
negative regulation of biosynthetic process GO:0009890 65 0.044
negative regulation of rna biosynthetic process GO:1902679 53 0.044
positive regulation of phosphorus metabolic process GO:0010562 56 0.042
regulation of cellular biosynthetic process GO:0031326 189 0.042
regulation of mitotic cell cycle GO:0007346 76 0.042
negative regulation of rna metabolic process GO:0051253 53 0.042
tube development GO:0035295 126 0.042
single organism catabolic process GO:0044712 129 0.042
mapk cascade GO:0000165 31 0.041
nucleus localization GO:0051647 55 0.041
regulation of cell division GO:0051302 142 0.041
cellular macromolecule biosynthetic process GO:0034645 247 0.041
establishment of localization in cell GO:0051649 318 0.041
fertilization GO:0009566 63 0.041
Worm
behavior GO:0007610 527 0.041
multi organism behavior GO:0051705 389 0.041
regulation of cell morphogenesis GO:0022604 40 0.040
cellular component assembly GO:0022607 293 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.040
response to bacterium GO:0009617 86 0.039
ubiquitin dependent protein catabolic process GO:0006511 32 0.039
regulation of cellular metabolic process GO:0031323 305 0.039
response to biotic stimulus GO:0009607 101 0.039
epithelial cell proliferation GO:0050673 1 0.038
positive regulation of molecular function GO:0044093 61 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.038
protein complex subunit organization GO:0071822 280 0.038
regulation of organ morphogenesis GO:2000027 4 0.038
regulation of epithelial cell proliferation GO:0050678 1 0.037
reproductive behavior GO:0019098 387 0.037
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.037
establishment of spindle localization GO:0051293 51 0.037
regulation of cell cycle GO:0051726 194 0.037
regulation of behavior GO:0050795 97 0.037
oogenesis GO:0048477 229 0.036
establishment of nucleus localization GO:0040023 55 0.036
organic cyclic compound catabolic process GO:1901361 119 0.035
anatomical structure formation involved in morphogenesis GO:0048646 250 0.035
cell fate commitment GO:0045165 139 0.035
positive regulation of neuron differentiation GO:0045666 4 0.034
regulation of anatomical structure morphogenesis GO:0022603 51 0.034
multicellular organismal reproductive behavior GO:0033057 384 0.034
nuclear migration GO:0007097 54 0.034
regulation of apoptotic process GO:0042981 36 0.033
regulation of nervous system development GO:0051960 41 0.033
cellular protein catabolic process GO:0044257 37 0.033
cytokinesis GO:0000910 80 0.033
cell surface receptor signaling pathway GO:0007166 149 0.033
cellular macromolecule localization GO:0070727 75 0.033
negative regulation of metabolic process GO:0009892 240 0.032
single organism transport GO:0044765 447 0.032
cellular response to dna damage stimulus GO:0006974 41 0.032
positive regulation of cell projection organization GO:0031346 4 0.032
regulation of signaling GO:0023051 172 0.031
positive regulation of cellular component organization GO:0051130 34 0.030
negative regulation of cellular metabolic process GO:0031324 95 0.030
actin filament based process GO:0030029 191 0.030
neuron differentiation GO:0030182 217 0.030
regulation of nitrogen compound metabolic process GO:0051171 222 0.030
system process GO:0003008 136 0.030
negative regulation of signal transduction GO:0009968 60 0.030
organelle localization GO:0051640 127 0.030
small gtpase mediated signal transduction GO:0007264 32 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.029
actin cytoskeleton organization GO:0030036 184 0.029
aromatic compound catabolic process GO:0019439 116 0.029
response to oxygen containing compound GO:1901700 44 0.029
regulation of locomotion GO:0040012 161 0.028
posttranscriptional gene silencing by rna GO:0035194 143 0.028
protein phosphorylation GO:0006468 85 0.028
negative regulation of developmental process GO:0051093 227 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.028
positive regulation of cellular catabolic process GO:0031331 35 0.028
response to other organism GO:0051707 101 0.028
dna metabolic process GO:0006259 74 0.027
positive regulation of catalytic activity GO:0043085 59 0.027
positive regulation of cell differentiation GO:0045597 8 0.027
organelle assembly GO:0070925 214 0.027
regulation of muscle cell differentiation GO:0051147 1 0.027
establishment or maintenance of cell polarity GO:0007163 63 0.027
regulation of intracellular signal transduction GO:1902531 77 0.026
male gamete generation GO:0048232 41 0.026
inductive cell migration GO:0040039 145 0.026
ion transport GO:0006811 113 0.026
response to temperature stimulus GO:0009266 66 0.026
myofibril assembly GO:0030239 154 0.025
regulation of gene expression epigenetic GO:0040029 163 0.025
cell cycle phase transition GO:0044770 19 0.025
wnt signaling pathway GO:0016055 27 0.025
regulation of cell proliferation GO:0042127 105 0.025
positive regulation of nucleic acid templated transcription GO:1903508 102 0.025
muscle cell development GO:0055001 158 0.024
establishment of organelle localization GO:0051656 123 0.024
negative regulation of cell communication GO:0010648 61 0.024
generation of neurons GO:0048699 235 0.023
multi organism reproductive behavior GO:0044705 387 0.023
negative regulation of response to stimulus GO:0048585 73 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.022
regeneration GO:0031099 4 0.022
heterocycle catabolic process GO:0046700 119 0.022
molting cycle GO:0042303 281 0.021
cellular protein localization GO:0034613 75 0.021
regulation of multi organism process GO:0043900 69 0.020
negative regulation of programmed cell death GO:0043069 19 0.020
cellular response to chemical stimulus GO:0070887 129 0.020
regulation of phosphate metabolic process GO:0019220 81 0.020
taxis GO:0042330 128 0.020
regulation of nuclear division GO:0051783 115 0.019
rna interference GO:0016246 137 0.019
single fertilization GO:0007338 61 0.019
Worm
mrna catabolic process GO:0006402 16 0.019
tube morphogenesis GO:0035239 79 0.019
macromolecular complex assembly GO:0065003 193 0.018
chromosome segregation GO:0007059 180 0.018
response to inorganic substance GO:0010035 50 0.018
cellular component assembly involved in morphogenesis GO:0010927 183 0.018
positive regulation of chromosome organization GO:2001252 2 0.018
phagocytosis engulfment GO:0006911 98 0.018
regulation of response to wounding GO:1903034 1 0.017
engulfment of apoptotic cell GO:0043652 94 0.017
organonitrogen compound metabolic process GO:1901564 151 0.017
dauer larval development GO:0040024 92 0.017
regulation of programmed cell death GO:0043067 50 0.017
protein complex biogenesis GO:0070271 186 0.017
mitotic sister chromatid segregation GO:0000070 38 0.017
embryonic pattern specification GO:0009880 21 0.017
microtubule based process GO:0007017 182 0.017
ribonucleotide metabolic process GO:0009259 99 0.017
cellular macromolecular complex assembly GO:0034622 184 0.017
response to nutrient levels GO:0031667 35 0.017
secretion by cell GO:0032940 138 0.016
organism emergence from protective structure GO:0071684 48 0.016
chromosome organization involved in meiosis GO:0070192 25 0.016
protein localization GO:0008104 205 0.016
memory GO:0007613 3 0.016
defense response to bacterium GO:0042742 86 0.016
cell cell signaling GO:0007267 118 0.016
axonogenesis GO:0007409 102 0.016
membrane depolarization GO:0051899 1 0.016
meiotic chromosome segregation GO:0045132 139 0.016
sensory organ morphogenesis GO:0090596 2 0.016
multi multicellular organism process GO:0044706 390 0.015
establishment of mitotic spindle orientation GO:0000132 28 0.015
protein oligomerization GO:0051259 4 0.015
cellular protein complex assembly GO:0043623 178 0.015
positive regulation of cell cycle GO:0045787 55 0.015
oocyte construction GO:0007308 2 0.015
cell projection morphogenesis GO:0048858 148 0.015
actomyosin structure organization GO:0031032 154 0.015
cell growth GO:0016049 44 0.015
organophosphate catabolic process GO:0046434 81 0.015
vulval development GO:0040025 333 0.015
signal transduction by phosphorylation GO:0023014 31 0.015
regulation of cellular catabolic process GO:0031329 51 0.015
striated muscle cell differentiation GO:0051146 158 0.014
cell substrate adhesion GO:0031589 1 0.014
axon development GO:0061564 163 0.014
response to heat GO:0009408 50 0.014
innate immune response GO:0045087 190 0.014
stem cell proliferation GO:0072089 9 0.014
small molecule metabolic process GO:0044281 186 0.013
negative regulation of multicellular organismal process GO:0051241 236 0.013
cell type specific apoptotic process GO:0097285 4 0.013
ras protein signal transduction GO:0007265 31 0.013
posttranscriptional gene silencing GO:0016441 143 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
g1 s transition of mitotic cell cycle GO:0000082 2 0.013
stem cell division GO:0017145 18 0.013
response to endogenous stimulus GO:0009719 33 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.013
regulation of reproductive process GO:2000241 66 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.013
muscle tissue development GO:0060537 1 0.013
response to extracellular stimulus GO:0009991 38 0.013
regulation of cellular component movement GO:0051270 62 0.013
organ morphogenesis GO:0009887 67 0.012
myosin filament organization GO:0031033 138 0.012
positive regulation of catabolic process GO:0009896 38 0.012
establishment of mitotic spindle localization GO:0040001 41 0.012
cellular response to abiotic stimulus GO:0071214 4 0.012
cell cycle g1 s phase transition GO:0044843 2 0.012
single organism biosynthetic process GO:0044711 91 0.012
intracellular transport GO:0046907 77 0.012
developmental growth involved in morphogenesis GO:0060560 37 0.012
post embryonic organ development GO:0048569 336 0.012
response to starvation GO:0042594 26 0.012
positive regulation of cellular protein catabolic process GO:1903364 3 0.012
phagocytosis GO:0006909 115 0.012
regulation of cytoplasmic transport GO:1903649 3 0.012
chemosensory behavior GO:0007635 33 0.012
regulation of response to stress GO:0080134 28 0.012
cell maturation GO:0048469 26 0.012
regulation of mapk cascade GO:0043408 23 0.012
response to topologically incorrect protein GO:0035966 82 0.012
myosin filament assembly GO:0031034 138 0.012
regulation of catalytic activity GO:0050790 78 0.011
membrane invagination GO:0010324 98 0.011
chemotaxis GO:0006935 120 0.011
negative regulation of signaling GO:0023057 61 0.011
regulation of canonical wnt signaling pathway GO:0060828 1 0.011
chromosome organization GO:0051276 104 0.011
positive regulation of signaling GO:0023056 66 0.011
dna repair GO:0006281 23 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
neuron projection development GO:0031175 187 0.011
cell proliferation GO:0008283 116 0.011
epithelial cell differentiation GO:0030855 17 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.011
rna catabolic process GO:0006401 21 0.011
protein complex assembly GO:0006461 186 0.011
positive regulation of locomotion GO:0040017 42 0.011
gene silencing by rna GO:0031047 143 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
skin development GO:0043588 24 0.011
dsrna fragmentation GO:0031050 10 0.011
apoptotic cell clearance GO:0043277 111 0.011
rna polyadenylation GO:0043631 3 0.011
muscle cell differentiation GO:0042692 171 0.011
regulation of cell motility GO:2000145 57 0.011
establishment of spindle orientation GO:0051294 34 0.010
nucleobase containing small molecule metabolic process GO:0055086 115 0.010
negative regulation of response to external stimulus GO:0032102 3 0.010
positive regulation of signal transduction GO:0009967 40 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.010
phosphate containing compound metabolic process GO:0006796 232 0.010
establishment of cell polarity GO:0030010 46 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.010
regulation of anatomical structure size GO:0090066 46 0.010
enzyme linked receptor protein signaling pathway GO:0007167 50 0.010

npp-22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org