Caenorhabditis elegans

27 known processes

mis-12 (CELE_Y47G6A.24)

Protein MIS-12

mis-12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.651
single organism organelle organization GO:1902589 501 0.606
nucleic acid metabolic process GO:0090304 299 0.592
embryo development GO:0009790 3052 0.542
locomotion GO:0040011 1634 0.514
post embryonic development GO:0009791 2152 0.503
single organism reproductive process GO:0044702 1196 0.498
regulation of nematode larval development GO:0061062 260 0.487
nucleobase containing compound metabolic process GO:0006139 406 0.417
organelle organization GO:0006996 783 0.404
meiotic cell cycle GO:0051321 335 0.400
cell cycle GO:0007049 526 0.399
developmental process involved in reproduction GO:0003006 1165 0.387
genitalia development GO:0048806 741 0.382
reproductive system development GO:0061458 850 0.344
establishment of localization GO:0051234 1171 0.330
negative regulation of biological process GO:0048519 567 0.329
multicellular organism reproduction GO:0032504 819 0.322
macromolecular complex subunit organization GO:0043933 320 0.277
determination of adult lifespan GO:0008340 812 0.273
transcription from rna polymerase ii promoter GO:0006366 149 0.253
sex differentiation GO:0007548 909 0.250
vesicle mediated transport GO:0016192 852 0.249
gamete generation GO:0007276 461 0.243
reproductive structure development GO:0048608 850 0.219
development of primary sexual characteristics GO:0045137 840 0.213
hermaphrodite genitalia development GO:0040035 734 0.213
organic cyclic compound biosynthetic process GO:1901362 195 0.207
nucleobase containing compound biosynthetic process GO:0034654 184 0.197
cellular response to stress GO:0033554 162 0.190
germ cell development GO:0007281 351 0.187
regulation of multicellular organismal process GO:0051239 726 0.178
gonad development GO:0008406 840 0.176
meiotic nuclear division GO:0007126 300 0.166
vulval development GO:0040025 333 0.162
macromolecule localization GO:0033036 771 0.161
multicellular organism growth GO:0035264 385 0.158
cellular component biogenesis GO:0044085 297 0.154
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.153
regulation of metabolic process GO:0019222 478 0.153
multicellular organismal reproductive process GO:0048609 815 0.149
organ development GO:0048513 1102 0.145
rna metabolic process GO:0016070 228 0.141
regulation of developmental process GO:0050793 684 0.128
regulation of multicellular organismal development GO:2000026 317 0.128
negative regulation of vulval development GO:0040027 206 0.128
cellular catabolic process GO:0044248 199 0.122
organelle fission GO:0048285 363 0.121
biosynthetic process GO:0009058 323 0.119
catabolic process GO:0009056 318 0.118
cellular response to dna damage stimulus GO:0006974 41 0.117
cell cycle process GO:0022402 482 0.117
single organism localization GO:1902578 518 0.113
growth GO:0040007 562 0.113
regulation of gene expression GO:0010468 366 0.113
cell development GO:0048468 696 0.112
macromolecule modification GO:0043412 218 0.112
endocytosis GO:0006897 819 0.110
aging GO:0007568 812 0.109
negative regulation of macromolecule metabolic process GO:0010605 229 0.108
cellular protein modification process GO:0006464 207 0.108
cell division GO:0051301 262 0.105
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.104
sexual reproduction GO:0019953 546 0.102
negative regulation of multicellular organismal process GO:0051241 236 0.101
regulation of biological quality GO:0065008 741 0.098
meiotic cell cycle process GO:1903046 170 0.097
multicellular organismal aging GO:0010259 812 0.090
mitotic spindle organization GO:0007052 81 0.089
maintenance of location GO:0051235 580 0.088
regulation of nitrogen compound metabolic process GO:0051171 222 0.088
lipid localization GO:0010876 573 0.087
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.084
organic substance catabolic process GO:1901575 294 0.084
cellular localization GO:0051641 360 0.083
transport GO:0006810 1093 0.082
regulation of rna metabolic process GO:0051252 173 0.081
regulation of primary metabolic process GO:0080090 292 0.081
female gamete generation GO:0007292 254 0.081
positive regulation of multicellular organismal process GO:0051240 417 0.079
regulation of growth GO:0040008 409 0.078
lipid storage GO:0019915 565 0.076
developmental growth GO:0048589 412 0.075
dna repair GO:0006281 23 0.074
oogenesis GO:0048477 229 0.072
protein complex subunit organization GO:0071822 280 0.072
regulation of cellular biosynthetic process GO:0031326 189 0.071
negative regulation of developmental process GO:0051093 227 0.070
phosphate containing compound metabolic process GO:0006796 232 0.068
organic substance biosynthetic process GO:1901576 323 0.067
regulation of gene expression epigenetic GO:0040029 163 0.066
regulation of cellular component organization GO:0051128 248 0.064
multi organism behavior GO:0051705 389 0.062
post embryonic organ development GO:0048569 336 0.061
nucleic acid templated transcription GO:0097659 169 0.058
regulation of multicellular organism growth GO:0040014 373 0.057
heterocycle biosynthetic process GO:0018130 187 0.057
positive regulation of growth GO:0045927 369 0.056
negative regulation of post embryonic development GO:0048581 208 0.056
regulation of macromolecule metabolic process GO:0060255 421 0.055
body morphogenesis GO:0010171 620 0.055
small molecule metabolic process GO:0044281 186 0.054
negative regulation of nematode larval development GO:0061064 208 0.053
organophosphate metabolic process GO:0019637 125 0.053
autophagy GO:0006914 29 0.053
meiotic chromosome segregation GO:0045132 139 0.052
behavior GO:0007610 527 0.051
protein metabolic process GO:0019538 422 0.050
multi organism reproductive process GO:0044703 867 0.050
multicellular organismal reproductive behavior GO:0033057 384 0.050
positive regulation of developmental process GO:0051094 408 0.049
negative regulation of cellular process GO:0048523 239 0.048
heterocycle catabolic process GO:0046700 119 0.046
regulation of meiotic cell cycle GO:0051445 136 0.046
phosphorus metabolic process GO:0006793 232 0.045
positive regulation of developmental growth GO:0048639 354 0.044
single organism transport GO:0044765 447 0.044
cytoskeleton organization GO:0007010 339 0.043
cellular component assembly GO:0022607 293 0.042
negative regulation of cellular metabolic process GO:0031324 95 0.042
reproductive behavior GO:0019098 387 0.042
dna metabolic process GO:0006259 74 0.041
single organism catabolic process GO:0044712 129 0.041
regulation of transcription dna templated GO:0006355 164 0.040
carbohydrate derivative metabolic process GO:1901135 141 0.040
regulation of vulval development GO:0040028 248 0.039
response to external stimulus GO:0009605 289 0.038
cell motility GO:0048870 313 0.038
cell migration GO:0016477 306 0.038
macromolecule catabolic process GO:0009057 202 0.038
regulation of developmental growth GO:0048638 389 0.038
cell death GO:0008219 547 0.036
microtubule based process GO:0007017 182 0.036
protein complex assembly GO:0006461 186 0.036
regulation of cellular metabolic process GO:0031323 305 0.036
positive regulation of multicellular organism growth GO:0040018 352 0.036
macromolecular complex assembly GO:0065003 193 0.035
multi multicellular organism process GO:0044706 390 0.035
cellular biosynthetic process GO:0044249 315 0.035
regulation of response to stimulus GO:0048583 243 0.035
negative regulation of gene expression GO:0010629 217 0.035
oocyte development GO:0048599 44 0.034
aromatic compound biosynthetic process GO:0019438 192 0.034
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.033
negative regulation of metabolic process GO:0009892 240 0.032
organonitrogen compound metabolic process GO:1901564 151 0.031
protein catabolic process GO:0030163 162 0.031
cellular component movement GO:0006928 388 0.031
apoptotic cell clearance GO:0043277 111 0.031
regulation of post embryonic development GO:0048580 260 0.030
protein localization GO:0008104 205 0.029
gene silencing GO:0016458 143 0.029
cellular nitrogen compound biosynthetic process GO:0044271 192 0.029
protein complex biogenesis GO:0070271 186 0.028
apoptotic process GO:0006915 478 0.028
receptor mediated endocytosis GO:0006898 715 0.028
organelle assembly GO:0070925 214 0.028
cellular protein metabolic process GO:0044267 279 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.026
localization of cell GO:0051674 313 0.026
establishment of localization in cell GO:0051649 318 0.026
nucleobase containing compound catabolic process GO:0034655 114 0.026
signal transduction GO:0007165 317 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.025
cellular macromolecule biosynthetic process GO:0034645 247 0.025
organic substance transport GO:0071702 113 0.025
cellular nitrogen compound catabolic process GO:0044270 119 0.025
organophosphate catabolic process GO:0046434 81 0.025
tube development GO:0035295 126 0.024
chromosome organization GO:0051276 104 0.024
regulation of catabolic process GO:0009894 57 0.023
death GO:0016265 547 0.022
oviposition GO:0018991 364 0.022
organonitrogen compound catabolic process GO:1901565 90 0.022
multi organism reproductive behavior GO:0044705 387 0.022
phagocytosis GO:0006909 115 0.022
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.022
cell proliferation GO:0008283 116 0.022
chromosome segregation GO:0007059 180 0.022
embryonic morphogenesis GO:0048598 152 0.021
guanosine containing compound metabolic process GO:1901068 49 0.021
regulation of meiosis GO:0040020 94 0.021
purine ribonucleotide metabolic process GO:0009150 95 0.021
peptidyl amino acid modification GO:0018193 58 0.020
single organism biosynthetic process GO:0044711 91 0.020
regulation of biosynthetic process GO:0009889 189 0.020
positive regulation of metabolic process GO:0009893 187 0.020
purine nucleotide catabolic process GO:0006195 75 0.020
protein modification process GO:0036211 207 0.020
programmed cell death GO:0012501 500 0.020
membrane organization GO:0061024 135 0.020
regulation of cell proliferation GO:0042127 105 0.020
negative regulation of transcription dna templated GO:0045892 53 0.019
regulation of cell cycle GO:0051726 194 0.019
nucleoside phosphate catabolic process GO:1901292 77 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.019
organic cyclic compound catabolic process GO:1901361 119 0.019
purine containing compound metabolic process GO:0072521 95 0.018
macromolecule biosynthetic process GO:0009059 250 0.018
axon development GO:0061564 163 0.018
purine nucleoside metabolic process GO:0042278 92 0.018
cytokinesis GO:0000910 80 0.017
chromatin remodeling GO:0006338 2 0.017
regulation of cell communication GO:0010646 176 0.017
negative regulation of gene expression epigenetic GO:0045814 2 0.017
cellular component morphogenesis GO:0032989 318 0.016
protein phosphorylation GO:0006468 85 0.016
nucleotide metabolic process GO:0009117 108 0.016
positive regulation of macromolecule metabolic process GO:0010604 149 0.016
regulation of signal transduction GO:0009966 135 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.016
single organism cellular localization GO:1902580 72 0.016
cellular macromolecule catabolic process GO:0044265 73 0.015
regulation of macromolecule biosynthetic process GO:0010556 189 0.015
gene expression GO:0010467 412 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.015
negative regulation of biosynthetic process GO:0009890 65 0.014
response to abiotic stimulus GO:0009628 152 0.014
negative regulation of cellular biosynthetic process GO:0031327 65 0.014
taxis GO:0042330 128 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.014
rna biosynthetic process GO:0032774 169 0.014
ribonucleotide catabolic process GO:0009261 75 0.014
ribonucleoside catabolic process GO:0042454 77 0.014
protein oligomerization GO:0051259 4 0.014
intracellular transport GO:0046907 77 0.014
positive regulation of rna metabolic process GO:0051254 103 0.013
pronuclear migration GO:0035046 51 0.013
regulation of cell cycle process GO:0010564 145 0.013
carbohydrate derivative catabolic process GO:1901136 82 0.013
single organism intracellular transport GO:1902582 70 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.013
response to chemical GO:0042221 356 0.013
phagocytosis engulfment GO:0006911 98 0.013
ribose phosphate metabolic process GO:0019693 99 0.013
regulation of cell division GO:0051302 142 0.013
internal peptidyl lysine acetylation GO:0018393 3 0.013
purine nucleoside catabolic process GO:0006152 75 0.012
spindle organization GO:0007051 92 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
nucleoside triphosphate catabolic process GO:0009143 72 0.012
oxoacid metabolic process GO:0043436 47 0.012
positive regulation of phosphorus metabolic process GO:0010562 56 0.012
regulation of molecular function GO:0065009 89 0.012
positive regulation of protein modification process GO:0031401 29 0.012
regulation of cellular catabolic process GO:0031329 51 0.012
rna interference GO:0016246 137 0.012
ribonucleoside metabolic process GO:0009119 98 0.012
nucleoside phosphate metabolic process GO:0006753 108 0.012
homeostatic process GO:0042592 51 0.012
negative regulation of rna metabolic process GO:0051253 53 0.012
purine nucleotide metabolic process GO:0006163 95 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
aromatic compound catabolic process GO:0019439 116 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
regulation of rna biosynthetic process GO:2001141 165 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
regulation of nuclear division GO:0051783 115 0.011
dna recombination GO:0006310 19 0.011
regulation of nucleic acid templated transcription GO:1903506 165 0.011
gtp metabolic process GO:0046039 46 0.011
defense response GO:0006952 296 0.011
myosin filament organization GO:0031033 138 0.011
neuron recognition GO:0008038 83 0.011
response to wounding GO:0009611 4 0.011
regulation of multi organism process GO:0043900 69 0.011
protein modification by small protein conjugation or removal GO:0070647 40 0.011
positive regulation of catalytic activity GO:0043085 59 0.011
protein deubiquitination GO:0016579 2 0.010
posttranscriptional gene silencing GO:0016441 143 0.010
head development GO:0060322 1 0.010
intracellular signal transduction GO:0035556 96 0.010
pattern specification process GO:0007389 59 0.010
cell morphogenesis GO:0000902 163 0.010
carboxylic acid metabolic process GO:0019752 34 0.010
generation of neurons GO:0048699 235 0.010

mis-12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org