Caenorhabditis elegans

68 known processes

unc-13 (CELE_ZK524.2)

Protein UNC-13

unc-13 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of pharyngeal pumping GO:0043051 36 0.662
regulation of neurotransmitter levels GO:0001505 36 0.376
Mouse Fly
single organism transport GO:0044765 447 0.374
Mouse Fly
behavior GO:0007610 527 0.369
transport GO:0006810 1093 0.366
Mouse Fly
signaling GO:0023052 401 0.336
Mouse Fly
neurotransmitter secretion GO:0007269 26 0.319
Mouse Fly
establishment of vesicle localization GO:0051650 23 0.256
Mouse Fly
single organism localization GO:1902578 518 0.234
Mouse Fly
signal release GO:0023061 28 0.228
Mouse Fly
organelle localization GO:0051640 127 0.222
Mouse Fly
multicellular organism reproduction GO:0032504 819 0.215
establishment of organelle localization GO:0051656 123 0.207
Mouse Fly
single organism signaling GO:0044700 401 0.206
Mouse Fly
protein catabolic process GO:0030163 162 0.200
larval behavior GO:0030537 5 0.196
embryo development ending in birth or egg hatching GO:0009792 2992 0.172
multi organism reproductive behavior GO:0044705 387 0.171
neurotransmitter transport GO:0006836 32 0.146
Mouse Fly
catabolic process GO:0009056 318 0.139
multi organism reproductive process GO:0044703 867 0.132
vesicle mediated transport GO:0016192 852 0.129
Mouse Fly
apoptotic process GO:0006915 478 0.128
synaptic vesicle localization GO:0097479 22 0.127
Mouse Fly
cellular component biogenesis GO:0044085 297 0.119
Mouse
secretion GO:0046903 147 0.117
Mouse Fly
embryo development GO:0009790 3052 0.114
secretion by cell GO:0032940 138 0.109
Mouse Fly
reproductive behavior GO:0019098 387 0.107
establishment of localization GO:0051234 1171 0.107
Mouse Fly
oviposition GO:0018991 364 0.094
multicellular organismal reproductive behavior GO:0033057 384 0.094
macromolecule catabolic process GO:0009057 202 0.093
neuron development GO:0048666 199 0.093
cellular component movement GO:0006928 388 0.092
g protein coupled receptor signaling pathway GO:0007186 46 0.086
cell development GO:0048468 696 0.082
regulation of feeding behavior GO:0060259 38 0.082
cell projection morphogenesis GO:0048858 148 0.078
body morphogenesis GO:0010171 620 0.076
organonitrogen compound catabolic process GO:1901565 90 0.076
single organism organelle organization GO:1902589 501 0.075
Mouse
macromolecule localization GO:0033036 771 0.075
synaptic vesicle transport GO:0048489 21 0.074
Mouse Fly
response to abiotic stimulus GO:0009628 152 0.069
regulation of multicellular organismal process GO:0051239 726 0.069
cell death GO:0008219 547 0.069
multi multicellular organism process GO:0044706 390 0.069
regulation of locomotion GO:0040012 161 0.068
regulation of synaptic transmission GO:0050804 34 0.067
Mouse
establishment of localization in cell GO:0051649 318 0.066
Mouse Fly
organelle organization GO:0006996 783 0.064
Mouse
organic substance catabolic process GO:1901575 294 0.063
multi organism behavior GO:0051705 389 0.062
macromolecular complex subunit organization GO:0043933 320 0.062
Mouse
synaptic transmission GO:0007268 106 0.060
Mouse Fly
cellular localization GO:0051641 360 0.060
Mouse Fly
neuron projection morphogenesis GO:0048812 114 0.058
pharyngeal pumping GO:0043050 58 0.057
protein metabolic process GO:0019538 422 0.055
negative regulation of vulval development GO:0040027 206 0.054
vesicle localization GO:0051648 24 0.052
Mouse Fly
cell part morphogenesis GO:0032990 152 0.052
post embryonic development GO:0009791 2152 0.052
multicellular organismal aging GO:0010259 812 0.051
lipid storage GO:0019915 565 0.051
death GO:0016265 547 0.050
cellular protein metabolic process GO:0044267 279 0.049
multicellular organism growth GO:0035264 385 0.049
protein complex subunit organization GO:0071822 280 0.048
Mouse
regulation of biological quality GO:0065008 741 0.048
Mouse Fly
cell cell signaling GO:0007267 118 0.047
Mouse Fly
eating behavior GO:0042755 59 0.046
programmed cell death GO:0012501 500 0.046
response to chemical GO:0042221 356 0.045
organ development GO:0048513 1102 0.045
developmental growth GO:0048589 412 0.045
regulation of localization GO:0032879 194 0.043
Mouse
maintenance of location GO:0051235 580 0.043
cellular component morphogenesis GO:0032989 318 0.043
locomotion GO:0040011 1634 0.043
lipid localization GO:0010876 573 0.043
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.043
cyclic nucleotide biosynthetic process GO:0009190 2 0.042
positive regulation of locomotion GO:0040017 42 0.042
regulation of behavior GO:0050795 97 0.042
regulation of metabolic process GO:0019222 478 0.041
regulation of developmental process GO:0050793 684 0.040
mitotic cell cycle process GO:1903047 194 0.039
ion transport GO:0006811 113 0.039
metal ion transport GO:0030001 49 0.039
regulation of growth GO:0040008 409 0.038
neuron projection development GO:0031175 187 0.038
cellular protein complex assembly GO:0043623 178 0.038
Mouse
development of primary sexual characteristics GO:0045137 840 0.037
cytoskeleton organization GO:0007010 339 0.037
cation transport GO:0006812 78 0.037
single organism behavior GO:0044708 83 0.037
regulation of developmental growth GO:0048638 389 0.036
muscle tissue development GO:0060537 1 0.036
positive regulation of growth GO:0045927 369 0.036
regulation of secretion by cell GO:1903530 21 0.035
Mouse
actomyosin structure organization GO:0031032 154 0.035
gene silencing GO:0016458 143 0.034
regulation of system process GO:0044057 27 0.034
cell morphogenesis involved in differentiation GO:0000904 112 0.034
aging GO:0007568 812 0.034
receptor mediated endocytosis GO:0006898 715 0.034
nucleobase containing compound metabolic process GO:0006139 406 0.034
growth GO:0040007 562 0.033
directional locomotion GO:0033058 14 0.033
endocytosis GO:0006897 819 0.032
Mouse
positive regulation of secretion by cell GO:1903532 14 0.031
Mouse
small molecule metabolic process GO:0044281 186 0.031
regulation of transport GO:0051049 91 0.031
Mouse
vesicle organization GO:0016050 15 0.030
Mouse
positive regulation of developmental growth GO:0048639 354 0.029
protein localization GO:0008104 205 0.029
regulation of multicellular organism growth GO:0040014 373 0.029
heterocycle catabolic process GO:0046700 119 0.029
synaptic vesicle endocytosis GO:0048488 3 0.028
Mouse
organonitrogen compound metabolic process GO:1901564 151 0.028
Mouse
regulation of neurotransmitter transport GO:0051588 16 0.028
Mouse
actin cytoskeleton organization GO:0030036 184 0.028
regulation of cellular component organization GO:0051128 248 0.027
post embryonic organ development GO:0048569 336 0.027
negative regulation of developmental process GO:0051093 227 0.027
regulation of cell communication GO:0010646 176 0.026
Mouse
organic cyclic compound catabolic process GO:1901361 119 0.026
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.026
positive regulation of multicellular organism growth GO:0040018 352 0.026
vulval development GO:0040025 333 0.026
purine ribonucleoside catabolic process GO:0046130 75 0.026
regulation of lipid metabolic process GO:0019216 4 0.026
negative regulation of cellular process GO:0048523 239 0.025
hermaphrodite genitalia development GO:0040035 734 0.025
feeding behavior GO:0007631 70 0.025
regulation of secretion GO:0051046 29 0.025
Mouse
dendrite development GO:0016358 42 0.024
axon development GO:0061564 163 0.024
determination of adult lifespan GO:0008340 812 0.024
regulation of striated muscle contraction GO:0006942 4 0.023
cellular component assembly involved in morphogenesis GO:0010927 183 0.023
multicellular organismal reproductive process GO:0048609 815 0.023
negative regulation of macromolecule metabolic process GO:0010605 229 0.023
organic substance transport GO:0071702 113 0.022
macromolecule modification GO:0043412 218 0.022
oxoacid metabolic process GO:0043436 47 0.022
purine containing compound metabolic process GO:0072521 95 0.022
nitrogen compound transport GO:0071705 49 0.022
regulation of nematode larval development GO:0061062 260 0.021
negative regulation of gene expression GO:0010629 217 0.021
organic substance biosynthetic process GO:1901576 323 0.021
regulation of neuromuscular synaptic transmission GO:1900073 1 0.021
glycosyl compound metabolic process GO:1901657 100 0.021
establishment or maintenance of cell polarity GO:0007163 63 0.020
cell morphogenesis GO:0000902 163 0.020
system process GO:0003008 136 0.020
nucleic acid templated transcription GO:0097659 169 0.020
regulation of catalytic activity GO:0050790 78 0.020
gonad development GO:0008406 840 0.020
cellular component assembly GO:0022607 293 0.020
Mouse
negative regulation of metabolic process GO:0009892 240 0.020
regulation of post embryonic development GO:0048580 260 0.019
protein modification process GO:0036211 207 0.019
developmental process involved in reproduction GO:0003006 1165 0.019
molting cycle GO:0042303 281 0.019
aromatic compound catabolic process GO:0019439 116 0.019
positive regulation of multicellular organismal process GO:0051240 417 0.019
backward locomotion GO:0043057 11 0.019
synaptic vesicle recycling GO:0036465 3 0.019
Mouse
cell recognition GO:0008037 85 0.019
gene silencing by rna GO:0031047 143 0.019
regulation of neuron projection development GO:0010975 31 0.019
negative regulation of biological process GO:0048519 567 0.019
ion homeostasis GO:0050801 21 0.019
single organism reproductive process GO:0044702 1196 0.019
locomotory behavior GO:0007626 40 0.019
genitalia development GO:0048806 741 0.019
germ cell development GO:0007281 351 0.019
positive regulation of developmental process GO:0051094 408 0.019
acetylcholine transport GO:0015870 16 0.018
cellular macromolecular complex assembly GO:0034622 184 0.018
Mouse
regulation of apoptotic signaling pathway GO:2001233 1 0.018
regulation of multicellular organismal development GO:2000026 317 0.018
exocytosis GO:0006887 15 0.018
Mouse Fly
rna interference GO:0016246 137 0.018
taxis GO:0042330 128 0.018
regulation of neurotransmitter secretion GO:0046928 16 0.018
Mouse
cell motility GO:0048870 313 0.017
adult behavior GO:0030534 3 0.017
skeletal muscle organ development GO:0060538 3 0.017
neuron differentiation GO:0030182 217 0.017
posttranscriptional regulation of gene expression GO:0010608 166 0.017
positive regulation of synaptic transmission GO:0050806 24 0.017
Mouse
specification of symmetry GO:0009799 9 0.017
cellular nitrogen compound catabolic process GO:0044270 119 0.017
membrane organization GO:0061024 135 0.017
negative regulation of nematode larval development GO:0061064 208 0.017
peptide hormone processing GO:0016486 2 0.016
ribonucleotide catabolic process GO:0009261 75 0.016
regulation of cellular localization GO:0060341 42 0.016
Mouse
purine nucleotide catabolic process GO:0006195 75 0.016
gtp metabolic process GO:0046039 46 0.016
cytokinesis GO:0000910 80 0.016
regulation of cell projection organization GO:0031344 38 0.016
regulation of molecular function GO:0065009 89 0.016
cell projection organization GO:0030030 231 0.016
generation of neurons GO:0048699 235 0.016
developmental growth involved in morphogenesis GO:0060560 37 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
myosin filament assembly GO:0031034 138 0.015
axonogenesis GO:0007409 102 0.015
synaptic vesicle exocytosis GO:0016079 5 0.015
Mouse Fly
regulation of gene expression epigenetic GO:0040029 163 0.015
cell growth GO:0016049 44 0.015
regulation of vulval development GO:0040028 248 0.015
ribonucleotide metabolic process GO:0009259 99 0.015
organelle assembly GO:0070925 214 0.015
regulation of response to stimulus GO:0048583 243 0.015
regulation of cell morphogenesis GO:0022604 40 0.015
muscle cell development GO:0055001 158 0.015
protein complex biogenesis GO:0070271 186 0.015
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 87 0.014
nucleus localization GO:0051647 55 0.014
nervous system development GO:0007399 253 0.014
nucleoside phosphate catabolic process GO:1901292 77 0.014
regulation of exocytosis GO:0017157 1 0.014
cellular amine metabolic process GO:0044106 15 0.014
inductive cell migration GO:0040039 145 0.014
reproductive structure development GO:0048608 850 0.014
anatomical structure formation involved in morphogenesis GO:0048646 250 0.014
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.014
establishment of cell polarity GO:0030010 46 0.013
reproductive system development GO:0061458 850 0.013
nucleoside catabolic process GO:0009164 78 0.013
nucleobase containing compound biosynthetic process GO:0034654 184 0.013
phosphorus metabolic process GO:0006793 232 0.013
developmental cell growth GO:0048588 39 0.013
cell migration GO:0016477 306 0.013
myosin filament organization GO:0031033 138 0.013
establishment of synaptic vesicle localization GO:0097480 21 0.013
Mouse Fly
response to wounding GO:0009611 4 0.013
purine ribonucleotide metabolic process GO:0009150 95 0.013
head development GO:0060322 1 0.013
sexual reproduction GO:0019953 546 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
intracellular transport GO:0046907 77 0.013
actin filament based process GO:0030029 191 0.013
transmembrane transport GO:0055085 110 0.013
striated muscle cell differentiation GO:0051146 158 0.013
homeostatic process GO:0042592 51 0.013
neurogenesis GO:0022008 236 0.013
rna metabolic process GO:0016070 228 0.013
nucleotide metabolic process GO:0009117 108 0.013
regulation of biosynthetic process GO:0009889 189 0.012
negative regulation of multicellular organismal process GO:0051241 236 0.012
mitotic nuclear envelope reassembly GO:0007084 3 0.012
filopodium assembly GO:0046847 2 0.012
aromatic compound biosynthetic process GO:0019438 192 0.012
neuron recognition GO:0008038 83 0.012
defecation GO:0030421 47 0.012
cuticle development GO:0042335 100 0.012
regulation of neurogenesis GO:0050767 40 0.012
establishment of nucleus localization GO:0040023 55 0.012
cell surface receptor signaling pathway GO:0007166 149 0.012
regulation of acetylcholine secretion neurotransmission GO:0014056 9 0.012
signal transduction GO:0007165 317 0.011
acetylcholine secretion GO:0061526 11 0.011
organic acid metabolic process GO:0006082 47 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.011
cellular biosynthetic process GO:0044249 315 0.011
excretion GO:0007588 49 0.011
cell division GO:0051301 262 0.011
myofibril assembly GO:0030239 154 0.011
neurological system process GO:0050877 53 0.011
muscle structure development GO:0061061 191 0.011
microtubule based process GO:0007017 182 0.011
regulation of kinase activity GO:0043549 29 0.011
neuromuscular junction development GO:0007528 2 0.011
Mouse
single organism catabolic process GO:0044712 129 0.011
cellular protein modification process GO:0006464 207 0.010
gamete generation GO:0007276 461 0.010
regulation of macromolecule metabolic process GO:0060255 421 0.010
macromolecular complex assembly GO:0065003 193 0.010
Mouse
axon guidance GO:0007411 82 0.010
cognition GO:0050890 27 0.010
axonal fasciculation GO:0007413 79 0.010
nucleoside metabolic process GO:0009116 99 0.010
hormone transport GO:0009914 2 0.010
nucleotide catabolic process GO:0009166 77 0.010

unc-13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
hypertrophic cardiomyopathy DOID:11984 0 0.030
myopathy DOID:423 0 0.030
muscular disease DOID:0080000 0 0.030
heart disease DOID:114 0 0.030
cardiomyopathy DOID:0050700 0 0.030
intrinsic cardiomyopathy DOID:0060036 0 0.030
cardiovascular system disease DOID:1287 0 0.030
musculoskeletal system disease DOID:17 0 0.030
muscle tissue disease DOID:66 0 0.030
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
muscular dystrophy DOID:9884 0 0.016
nervous system disease DOID:863 0 0.012
neuromuscular disease DOID:440 0 0.011
charcot marie tooth disease type 2 DOID:0050539 0 0.011
charcot marie tooth disease DOID:10595 0 0.011
neuropathy DOID:870 0 0.011