Caenorhabditis elegans

35 known processes

spe-4 (CELE_ZK524.1)

Protein SPE-4

spe-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.506
embryo development GO:0009790 3052 0.301
post embryonic development GO:0009791 2152 0.255
vesicle mediated transport GO:0016192 852 0.251
endocytosis GO:0006897 819 0.246
developmental process involved in reproduction GO:0003006 1165 0.244
receptor mediated endocytosis GO:0006898 715 0.211
positive regulation of cellular process GO:0048522 332 0.189
multicellular organismal reproductive process GO:0048609 815 0.147
regulation of biological quality GO:0065008 741 0.142
macromolecule localization GO:0033036 771 0.134
signal transduction GO:0007165 317 0.128
cell development GO:0048468 696 0.125
locomotion GO:0040011 1634 0.122
organelle organization GO:0006996 783 0.119
sexual reproduction GO:0019953 546 0.107
establishment of localization GO:0051234 1171 0.104
organ development GO:0048513 1102 0.103
gamete generation GO:0007276 461 0.100
body morphogenesis GO:0010171 620 0.091
transport GO:0006810 1093 0.090
single organism signaling GO:0044700 401 0.087
single organism reproductive process GO:0044702 1196 0.083
lipid localization GO:0010876 573 0.082
programmed cell death GO:0012501 500 0.082
maintenance of location GO:0051235 580 0.081
single organism organelle organization GO:1902589 501 0.081
cellular component movement GO:0006928 388 0.078
cell death GO:0008219 547 0.078
lipid storage GO:0019915 565 0.076
growth GO:0040007 562 0.076
multi organism reproductive process GO:0044703 867 0.075
developmental growth GO:0048589 412 0.073
reproductive structure development GO:0048608 850 0.070
apoptotic process GO:0006915 478 0.070
regulation of multicellular organismal process GO:0051239 726 0.070
sex differentiation GO:0007548 909 0.067
genitalia development GO:0048806 741 0.067
regulation of metabolic process GO:0019222 478 0.065
negative regulation of biological process GO:0048519 567 0.065
development of primary sexual characteristics GO:0045137 840 0.064
nervous system development GO:0007399 253 0.064
regulation of growth GO:0040008 409 0.060
response to external stimulus GO:0009605 289 0.060
gonad development GO:0008406 840 0.058
reproductive system development GO:0061458 850 0.058
death GO:0016265 547 0.057
localization of cell GO:0051674 313 0.056
cell motility GO:0048870 313 0.055
regulation of cellular metabolic process GO:0031323 305 0.053
regulation of developmental process GO:0050793 684 0.052
germ cell development GO:0007281 351 0.051
response to chemical GO:0042221 356 0.049
phosphate containing compound metabolic process GO:0006796 232 0.049
cellular component assembly GO:0022607 293 0.048
signaling GO:0023052 401 0.048
regulation of response to stimulus GO:0048583 243 0.047
cytoskeleton organization GO:0007010 339 0.047
protein metabolic process GO:0019538 422 0.046
cell migration GO:0016477 306 0.045
multicellular organism reproduction GO:0032504 819 0.045
regulation of multicellular organism growth GO:0040014 373 0.044
positive regulation of developmental process GO:0051094 408 0.042
negative regulation of cellular process GO:0048523 239 0.042
neuron differentiation GO:0030182 217 0.041
phosphorus metabolic process GO:0006793 232 0.040
regulation of developmental growth GO:0048638 389 0.039
positive regulation of developmental growth GO:0048639 354 0.038
cell projection organization GO:0030030 231 0.038
positive regulation of multicellular organismal process GO:0051240 417 0.038
multicellular organism growth GO:0035264 385 0.037
cellular component morphogenesis GO:0032989 318 0.035
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.035
regulation of primary metabolic process GO:0080090 292 0.034
hermaphrodite genitalia development GO:0040035 734 0.034
cellular response to stress GO:0033554 162 0.033
regulation of cell communication GO:0010646 176 0.033
nucleobase containing compound metabolic process GO:0006139 406 0.033
cell cycle process GO:0022402 482 0.033
aging GO:0007568 812 0.033
cellular component biogenesis GO:0044085 297 0.032
positive regulation of growth GO:0045927 369 0.032
response to abiotic stimulus GO:0009628 152 0.032
regulation of macromolecule metabolic process GO:0060255 421 0.031
regulation of phosphorus metabolic process GO:0051174 81 0.030
multicellular organismal aging GO:0010259 812 0.030
establishment of localization in cell GO:0051649 318 0.029
embryonic morphogenesis GO:0048598 152 0.029
cellular response to chemical stimulus GO:0070887 129 0.029
determination of adult lifespan GO:0008340 812 0.028
macromolecular complex subunit organization GO:0043933 320 0.028
actin filament based process GO:0030029 191 0.027
regulation of phosphate metabolic process GO:0019220 81 0.027
generation of neurons GO:0048699 235 0.027
positive regulation of metabolic process GO:0009893 187 0.027
cellular biosynthetic process GO:0044249 315 0.027
neuron development GO:0048666 199 0.026
positive regulation of multicellular organism growth GO:0040018 352 0.025
regulation of localization GO:0032879 194 0.025
female gamete generation GO:0007292 254 0.025
macromolecule catabolic process GO:0009057 202 0.024
behavior GO:0007610 527 0.024
organic substance catabolic process GO:1901575 294 0.023
nematode male tail tip morphogenesis GO:0045138 77 0.023
small molecule metabolic process GO:0044281 186 0.023
catabolic process GO:0009056 318 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.023
system process GO:0003008 136 0.023
anatomical structure formation involved in morphogenesis GO:0048646 250 0.023
protein complex subunit organization GO:0071822 280 0.023
neuron projection development GO:0031175 187 0.022
taxis GO:0042330 128 0.022
cellular protein modification process GO:0006464 207 0.021
multi organism behavior GO:0051705 389 0.021
nucleic acid templated transcription GO:0097659 169 0.021
chemotaxis GO:0006935 120 0.021
macromolecule modification GO:0043412 218 0.020
regulation of cell proliferation GO:0042127 105 0.020
regulation of multicellular organismal development GO:2000026 317 0.020
protein localization GO:0008104 205 0.020
single organism localization GO:1902578 518 0.019
head development GO:0060322 1 0.019
cell proliferation GO:0008283 116 0.019
cellular macromolecule biosynthetic process GO:0034645 247 0.019
cell recognition GO:0008037 85 0.019
reproductive behavior GO:0019098 387 0.019
multi multicellular organism process GO:0044706 390 0.019
cellular localization GO:0051641 360 0.019
positive regulation of cellular metabolic process GO:0031325 178 0.019
biosynthetic process GO:0009058 323 0.019
actin cytoskeleton organization GO:0030036 184 0.018
cellular protein metabolic process GO:0044267 279 0.018
aromatic compound biosynthetic process GO:0019438 192 0.018
regulation of cell differentiation GO:0045595 81 0.018
cellular nitrogen compound biosynthetic process GO:0044271 192 0.018
gene expression GO:0010467 412 0.018
oviposition GO:0018991 364 0.018
response to wounding GO:0009611 4 0.017
regulation of cell migration GO:0030334 55 0.017
protein modification process GO:0036211 207 0.017
nucleobase containing compound biosynthetic process GO:0034654 184 0.017
nucleic acid metabolic process GO:0090304 299 0.017
neurogenesis GO:0022008 236 0.016
nucleotide metabolic process GO:0009117 108 0.016
heterocycle biosynthetic process GO:0018130 187 0.016
regulation of organelle organization GO:0033043 164 0.016
oogenesis GO:0048477 229 0.016
rna metabolic process GO:0016070 228 0.016
cell substrate adhesion GO:0031589 1 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
macromolecule biosynthetic process GO:0009059 250 0.015
negative regulation of response to stimulus GO:0048585 73 0.015
male anatomical structure morphogenesis GO:0090598 78 0.015
macromolecular complex assembly GO:0065003 193 0.015
regulation of biosynthetic process GO:0009889 189 0.015
cellular response to organic substance GO:0071310 119 0.015
organelle localization GO:0051640 127 0.015
axon development GO:0061564 163 0.015
regulation of protein localization GO:0032880 50 0.014
cellular protein complex assembly GO:0043623 178 0.014
regulation of protein metabolic process GO:0051246 81 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.014
protein complex biogenesis GO:0070271 186 0.014
protein phosphorylation GO:0006468 85 0.014
microtubule based process GO:0007017 182 0.014
striated muscle cell differentiation GO:0051146 158 0.014
organic cyclic compound biosynthetic process GO:1901362 195 0.014
actomyosin structure organization GO:0031032 154 0.014
regulation of cellular component organization GO:0051128 248 0.014
regulation of cell cycle GO:0051726 194 0.013
multicellular organismal reproductive behavior GO:0033057 384 0.013
cellular macromolecular complex assembly GO:0034622 184 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
regulation of signaling GO:0023051 172 0.013
organic substance biosynthetic process GO:1901576 323 0.013
organonitrogen compound metabolic process GO:1901564 151 0.013
protein catabolic process GO:0030163 162 0.013
cuticle development GO:0042335 100 0.013
purine nucleotide metabolic process GO:0006163 95 0.013
male gamete generation GO:0048232 41 0.013
cell cycle GO:0007049 526 0.012
muscle structure development GO:0061061 191 0.012
regulation of nitrogen compound metabolic process GO:0051171 222 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
spermatogenesis GO:0007283 41 0.012
regulation of cellular biosynthetic process GO:0031326 189 0.012
purine containing compound metabolic process GO:0072521 95 0.012
organophosphate metabolic process GO:0019637 125 0.012
ribonucleotide metabolic process GO:0009259 99 0.012
male sex differentiation GO:0046661 86 0.011
single organism biosynthetic process GO:0044711 91 0.011
organelle fission GO:0048285 363 0.011
embryonic body morphogenesis GO:0010172 49 0.011
defense response GO:0006952 296 0.011
single organism catabolic process GO:0044712 129 0.011
regulation of cell motility GO:2000145 57 0.011
protein complex assembly GO:0006461 186 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
molting cycle GO:0042303 281 0.011
myosin filament organization GO:0031033 138 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.011
cell surface receptor signaling pathway GO:0007166 149 0.011
myofibril assembly GO:0030239 154 0.011
positive regulation of biosynthetic process GO:0009891 109 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
signal transduction involved in cell cycle checkpoint GO:0072395 1 0.011
muscle cell differentiation GO:0042692 171 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.010
myosin filament assembly GO:0031034 138 0.010
regulation of transport GO:0051049 91 0.010
regulation of rna metabolic process GO:0051252 173 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.010
actin cytoskeleton reorganization GO:0031532 4 0.010
cell projection morphogenesis GO:0048858 148 0.010

spe-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011