Caenorhabditis elegans

134 known processes

phb-1 (CELE_Y37E3.9)

Protein PHB-1

phb-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.388
post embryonic development GO:0009791 2152 0.345
embryo development ending in birth or egg hatching GO:0009792 2992 0.301
locomotion GO:0040011 1634 0.226
vesicle mediated transport GO:0016192 852 0.179
aging GO:0007568 812 0.176
single organism transport GO:0044765 447 0.141
cell development GO:0048468 696 0.127
cell death GO:0008219 547 0.120
positive regulation of cellular process GO:0048522 332 0.119
Human
multicellular organismal aging GO:0010259 812 0.116
gamete generation GO:0007276 461 0.116
establishment of localization in cell GO:0051649 318 0.111
signal transduction GO:0007165 317 0.091
Human
single organism localization GO:1902578 518 0.090
determination of adult lifespan GO:0008340 812 0.090
cellular localization GO:0051641 360 0.086
receptor mediated endocytosis GO:0006898 715 0.076
response to chemical GO:0042221 356 0.074
Human Fly
single organism signaling GO:0044700 401 0.074
Human
reproductive structure development GO:0048608 850 0.073
signaling GO:0023052 401 0.069
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.067
carbohydrate derivative metabolic process GO:1901135 141 0.066
organ development GO:0048513 1102 0.066
programmed cell death GO:0012501 500 0.065
multi organism reproductive process GO:0044703 867 0.065
regulation of response to stimulus GO:0048583 243 0.063
regulation of multicellular organismal process GO:0051239 726 0.060
gonad development GO:0008406 840 0.059
regulation of biological quality GO:0065008 741 0.058
organelle organization GO:0006996 783 0.057
death GO:0016265 547 0.056
regulation of developmental process GO:0050793 684 0.055
endocytosis GO:0006897 819 0.055
macromolecule localization GO:0033036 771 0.054
hermaphrodite genitalia development GO:0040035 734 0.052
nucleobase containing compound metabolic process GO:0006139 406 0.051
cell motility GO:0048870 313 0.050
cellular component assembly GO:0022607 293 0.048
apoptotic process GO:0006915 478 0.047
maintenance of location GO:0051235 580 0.047
lipid storage GO:0019915 565 0.046
cellular component movement GO:0006928 388 0.046
response to external stimulus GO:0009605 289 0.045
developmental growth GO:0048589 412 0.045
single organism reproductive process GO:0044702 1196 0.044
growth GO:0040007 562 0.042
development of primary sexual characteristics GO:0045137 840 0.042
negative regulation of biological process GO:0048519 567 0.041
Human Mouse
behavior GO:0007610 527 0.041
regulation of growth GO:0040008 409 0.040
organonitrogen compound metabolic process GO:1901564 151 0.040
transport GO:0006810 1093 0.039
body morphogenesis GO:0010171 620 0.038
developmental process involved in reproduction GO:0003006 1165 0.038
positive regulation of multicellular organism growth GO:0040018 352 0.038
small molecule metabolic process GO:0044281 186 0.037
macromolecular complex subunit organization GO:0043933 320 0.037
Human
positive regulation of developmental process GO:0051094 408 0.036
protein metabolic process GO:0019538 422 0.036
Human
sex differentiation GO:0007548 909 0.036
positive regulation of growth GO:0045927 369 0.036
organic substance transport GO:0071702 113 0.035
cellular component biogenesis GO:0044085 297 0.035
positive regulation of multicellular organismal process GO:0051240 417 0.035
lipid localization GO:0010876 573 0.035
multicellular organism growth GO:0035264 385 0.034
membrane organization GO:0061024 135 0.034
regulation of primary metabolic process GO:0080090 292 0.034
cellular protein metabolic process GO:0044267 279 0.032
Human
transmembrane transport GO:0055085 110 0.032
establishment of localization GO:0051234 1171 0.032
regulation of developmental growth GO:0048638 389 0.032
biosynthetic process GO:0009058 323 0.031
Human Mouse
secretion GO:0046903 147 0.031
ion transport GO:0006811 113 0.031
mitochondrion organization GO:0007005 20 0.031
nervous system development GO:0007399 253 0.030
single organism intracellular transport GO:1902582 70 0.030
negative regulation of metabolic process GO:0009892 240 0.030
Human Mouse
phosphate containing compound metabolic process GO:0006796 232 0.030
multicellular organismal reproductive process GO:0048609 815 0.030
organelle localization GO:0051640 127 0.028
catabolic process GO:0009056 318 0.027
response to wounding GO:0009611 4 0.027
neuromuscular junction development GO:0007528 2 0.026
establishment of organelle localization GO:0051656 123 0.026
cellular component morphogenesis GO:0032989 318 0.026
germ cell development GO:0007281 351 0.026
ribonucleoside triphosphate metabolic process GO:0009199 87 0.025
regulation of metabolic process GO:0019222 478 0.025
single organism membrane organization GO:0044802 35 0.025
organic substance catabolic process GO:1901575 294 0.024
sexual reproduction GO:0019953 546 0.024
cell migration GO:0016477 306 0.024
localization of cell GO:0051674 313 0.023
positive regulation of developmental growth GO:0048639 354 0.023
regulation of response to wounding GO:1903034 1 0.023
regulation of localization GO:0032879 194 0.023
purine containing compound metabolic process GO:0072521 95 0.023
secretion by cell GO:0032940 138 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.023
aromatic compound catabolic process GO:0019439 116 0.023
protein localization GO:0008104 205 0.022
phosphorus metabolic process GO:0006793 232 0.022
regulation of multicellular organism growth GO:0040014 373 0.022
reproductive system development GO:0061458 850 0.022
cellular biosynthetic process GO:0044249 315 0.022
Human Mouse
cell cell signaling GO:0007267 118 0.021
ribonucleoside monophosphate metabolic process GO:0009161 45 0.021
genitalia development GO:0048806 741 0.021
cellular macromolecule localization GO:0070727 75 0.021
cellular protein localization GO:0034613 75 0.020
cellular macromolecular complex assembly GO:0034622 184 0.020
intracellular transport GO:0046907 77 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.020
cellular protein complex assembly GO:0043623 178 0.020
carboxylic acid metabolic process GO:0019752 34 0.019
aromatic compound biosynthetic process GO:0019438 192 0.019
Human Mouse
oogenesis GO:0048477 229 0.019
negative regulation of cellular process GO:0048523 239 0.018
Human Mouse
gene expression GO:0010467 412 0.018
Human Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.018
purine nucleoside monophosphate metabolic process GO:0009126 43 0.018
protein complex biogenesis GO:0070271 186 0.018
regulation of cell communication GO:0010646 176 0.017
Human
myosin filament organization GO:0031033 138 0.017
positive regulation of metabolic process GO:0009893 187 0.017
Human
purine ribonucleotide metabolic process GO:0009150 95 0.017
cellular response to stress GO:0033554 162 0.017
Fly
regulation of signal transduction GO:0009966 135 0.017
Human
glycosyl compound metabolic process GO:1901657 100 0.016
ribosome biogenesis GO:0042254 4 0.016
purine nucleoside metabolic process GO:0042278 92 0.016
multicellular organism reproduction GO:0032504 819 0.015
neuron differentiation GO:0030182 217 0.015
purine nucleoside triphosphate catabolic process GO:0009146 72 0.015
molting cycle GO:0042303 281 0.015
protein modification process GO:0036211 207 0.014
Human
organic acid metabolic process GO:0006082 47 0.014
regulation of phosphorus metabolic process GO:0051174 81 0.014
cellular protein modification process GO:0006464 207 0.014
Human
protein complex assembly GO:0006461 186 0.014
multi multicellular organism process GO:0044706 390 0.014
striated muscle cell development GO:0055002 157 0.014
actin cytoskeleton organization GO:0030036 184 0.014
negative regulation of gene expression GO:0010629 217 0.014
Human Mouse
single organism organelle organization GO:1902589 501 0.014
actin filament based process GO:0030029 191 0.014
muscle structure development GO:0061061 191 0.013
organic substance biosynthetic process GO:1901576 323 0.013
Human Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.013
Human Mouse
actomyosin structure organization GO:0031032 154 0.013
negative regulation of signal transduction GO:0009968 60 0.013
Human
response to other organism GO:0051707 101 0.013
single organism cellular localization GO:1902580 72 0.013
regulation of intracellular signal transduction GO:1902531 77 0.013
calcium mediated signaling GO:0019722 3 0.013
phagocytosis GO:0006909 115 0.013
regulation of nitrogen compound metabolic process GO:0051171 222 0.013
single organism catabolic process GO:0044712 129 0.013
protein complex subunit organization GO:0071822 280 0.012
myosin filament assembly GO:0031034 138 0.012
female gamete generation GO:0007292 254 0.012
regulation of catalytic activity GO:0050790 78 0.012
myofibril assembly GO:0030239 154 0.012
regulation of organelle organization GO:0033043 164 0.012
ion transmembrane transport GO:0034220 91 0.012
carbohydrate derivative catabolic process GO:1901136 82 0.012
neurogenesis GO:0022008 236 0.012
regeneration GO:0031099 4 0.012
macromolecule catabolic process GO:0009057 202 0.012
positive regulation of cellular component organization GO:0051130 34 0.012
generation of neurons GO:0048699 235 0.012
cellular component assembly involved in morphogenesis GO:0010927 183 0.012
organophosphate metabolic process GO:0019637 125 0.012
defense response GO:0006952 296 0.012
regulation of nucleoside metabolic process GO:0009118 37 0.012
protein targeting to mitochondrion GO:0006626 2 0.012
macromolecule modification GO:0043412 218 0.011
Human
nucleoside phosphate metabolic process GO:0006753 108 0.011
nucleoside metabolic process GO:0009116 99 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
innate immune response GO:0045087 190 0.011
heterocycle catabolic process GO:0046700 119 0.011
macromolecule biosynthetic process GO:0009059 250 0.011
Human Mouse
regulation of cellular component organization GO:0051128 248 0.011
Human
ribonucleotide metabolic process GO:0009259 99 0.011
regulation of behavior GO:0050795 97 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
organelle assembly GO:0070925 214 0.011
response to endoplasmic reticulum stress GO:0034976 71 0.010
detection of abiotic stimulus GO:0009582 4 0.010
cation transport GO:0006812 78 0.010
nucleobase containing small molecule metabolic process GO:0055086 115 0.010
immune response GO:0006955 192 0.010
protein oligomerization GO:0051259 4 0.010
neuron projection development GO:0031175 187 0.010
cellular ketone metabolic process GO:0042180 14 0.010
regulation of multi organism process GO:0043900 69 0.010
proteolysis GO:0006508 61 0.010
muscle cell development GO:0055001 158 0.010
organic cyclic compound catabolic process GO:1901361 119 0.010

phb-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
immune system disease DOID:2914 0 0.011
nervous system disease DOID:863 0 0.011