Caenorhabditis elegans

27 known processes

ehs-1 (CELE_ZK1248.3)

Protein EHS-1

ehs-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism signaling GO:0044700 401 0.529
transport GO:0006810 1093 0.481
cellular localization GO:0051641 360 0.475
death GO:0016265 547 0.456
negative regulation of biological process GO:0048519 567 0.411
Fly
organ development GO:0048513 1102 0.406
signaling GO:0023052 401 0.387
vesicle mediated transport GO:0016192 852 0.372
establishment of localization GO:0051234 1171 0.248
signal transduction GO:0007165 317 0.232
Fly
programmed cell death GO:0012501 500 0.223
cell death GO:0008219 547 0.213
cell cycle GO:0007049 526 0.210
phosphate containing compound metabolic process GO:0006796 232 0.206
regulation of macromolecule metabolic process GO:0060255 421 0.187
regulation of metabolic process GO:0019222 478 0.175
gene expression GO:0010467 412 0.170
developmental process involved in reproduction GO:0003006 1165 0.170
regulation of developmental process GO:0050793 684 0.151
Fly
cellular component biogenesis GO:0044085 297 0.149
Human Fly
glycosyl compound metabolic process GO:1901657 100 0.143
apoptotic process GO:0006915 478 0.141
nucleobase containing compound metabolic process GO:0006139 406 0.139
phosphorus metabolic process GO:0006793 232 0.139
locomotion GO:0040011 1634 0.135
negative regulation of cellular process GO:0048523 239 0.134
Fly
post embryonic development GO:0009791 2152 0.131
cell cycle process GO:0022402 482 0.123
reproductive system development GO:0061458 850 0.123
establishment of localization in cell GO:0051649 318 0.119
positive regulation of cellular process GO:0048522 332 0.117
single organism reproductive process GO:0044702 1196 0.112
purine ribonucleoside metabolic process GO:0046128 92 0.109
multicellular organismal reproductive behavior GO:0033057 384 0.108
positive regulation of neurogenesis GO:0050769 4 0.106
regulation of signaling GO:0023051 172 0.106
Fly
organelle organization GO:0006996 783 0.105
Human
regulation of primary metabolic process GO:0080090 292 0.099
regulation of multicellular organismal process GO:0051239 726 0.098
Fly
regulation of locomotion GO:0040012 161 0.096
small gtpase mediated signal transduction GO:0007264 32 0.092
nucleotide metabolic process GO:0009117 108 0.091
cellular component assembly GO:0022607 293 0.091
Human Fly
embryo development GO:0009790 3052 0.089
body morphogenesis GO:0010171 620 0.086
ribonucleotide catabolic process GO:0009261 75 0.086
growth GO:0040007 562 0.086
Fly
regulation of growth GO:0040008 409 0.083
Fly
regulation of vesicle mediated transport GO:0060627 27 0.083
single organism transport GO:0044765 447 0.082
regulation of cell division GO:0051302 142 0.082
notch signaling pathway GO:0007219 22 0.082
Fly
head development GO:0060322 1 0.082
macromolecule localization GO:0033036 771 0.080
negative regulation of cellular component organization GO:0051129 33 0.079
embryo development ending in birth or egg hatching GO:0009792 2992 0.077
synaptic transmission GO:0007268 106 0.076
multi multicellular organism process GO:0044706 390 0.075
regulation of nervous system development GO:0051960 41 0.074
Fly
sex differentiation GO:0007548 909 0.073
positive regulation of growth GO:0045927 369 0.072
cell development GO:0048468 696 0.071
cell surface receptor signaling pathway GO:0007166 149 0.070
Fly
protein localization GO:0008104 205 0.069
establishment of organelle localization GO:0051656 123 0.069
protein complex subunit organization GO:0071822 280 0.069
Human
aging GO:0007568 812 0.068
cellular response to stress GO:0033554 162 0.067
receptor mediated endocytosis GO:0006898 715 0.067
membrane organization GO:0061024 135 0.063
Human
regulation of multicellular organismal development GO:2000026 317 0.063
Fly
positive regulation of multicellular organismal process GO:0051240 417 0.063
lipid storage GO:0019915 565 0.062
regulation of cell cycle GO:0051726 194 0.062
lipid localization GO:0010876 573 0.061
nucleoside catabolic process GO:0009164 78 0.058
cell type specific apoptotic process GO:0097285 4 0.058
regulation of biological quality GO:0065008 741 0.057
Fly
actin cytoskeleton organization GO:0030036 184 0.057
nucleoside phosphate metabolic process GO:0006753 108 0.055
maintenance of location GO:0051235 580 0.055
biosynthetic process GO:0009058 323 0.055
purine nucleotide catabolic process GO:0006195 75 0.054
developmental growth GO:0048589 412 0.053
Fly
positive regulation of developmental process GO:0051094 408 0.053
cellular macromolecule localization GO:0070727 75 0.052
behavior GO:0007610 527 0.052
regulation of cellular protein metabolic process GO:0032268 75 0.052
purine nucleoside triphosphate catabolic process GO:0009146 72 0.052
small molecule metabolic process GO:0044281 186 0.051
negative regulation of post embryonic development GO:0048581 208 0.051
regulation of localization GO:0032879 194 0.051
regulation of developmental growth GO:0048638 389 0.051
Fly
purine ribonucleotide metabolic process GO:0009150 95 0.051
carbohydrate derivative catabolic process GO:1901136 82 0.050
single organism intracellular transport GO:1902582 70 0.050
Human
synaptic vesicle endocytosis GO:0048488 3 0.050
regulation of nucleic acid templated transcription GO:1903506 165 0.049
gene silencing GO:0016458 143 0.049
hermaphrodite genitalia development GO:0040035 734 0.049
posttranscriptional gene silencing GO:0016441 143 0.049
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.048
ribonucleotide metabolic process GO:0009259 99 0.047
macromolecule biosynthetic process GO:0009059 250 0.047
glycosyl compound catabolic process GO:1901658 79 0.046
intracellular transport GO:0046907 77 0.046
Human
regulation of cell proliferation GO:0042127 105 0.045
heterocycle catabolic process GO:0046700 119 0.044
regulation of cellular metabolic process GO:0031323 305 0.044
ras protein signal transduction GO:0007265 31 0.044
organophosphate metabolic process GO:0019637 125 0.044
cell cell signaling GO:0007267 118 0.043
multicellular organismal aging GO:0010259 812 0.043
reproductive structure development GO:0048608 850 0.043
regulation of nuclear division GO:0051783 115 0.043
mesodermal cell migration GO:0008078 9 0.042
nucleobase containing compound catabolic process GO:0034655 114 0.042
cell motility GO:0048870 313 0.042
organelle localization GO:0051640 127 0.042
protein localization to plasma membrane GO:0072659 7 0.041
macromolecular complex subunit organization GO:0043933 320 0.041
Human
sensory perception GO:0007600 27 0.041
cellular response to chemical stimulus GO:0070887 129 0.041
endocytosis GO:0006897 819 0.040
establishment of vesicle localization GO:0051650 23 0.040
phagocytosis GO:0006909 115 0.040
positive regulation of cell migration GO:0030335 3 0.040
multicellular organism reproduction GO:0032504 819 0.039
nucleoside phosphate catabolic process GO:1901292 77 0.039
single organism localization GO:1902578 518 0.039
single organism cellular localization GO:1902580 72 0.039
gonad development GO:0008406 840 0.038
embryonic body morphogenesis GO:0010172 49 0.038
organophosphate catabolic process GO:0046434 81 0.038
regulation of macromolecule biosynthetic process GO:0010556 189 0.038
regulation of gtpase activity GO:0043087 30 0.037
intracellular signal transduction GO:0035556 96 0.037
positive regulation of developmental growth GO:0048639 354 0.036
regulation of gtp catabolic process GO:0033124 32 0.036
cellular component assembly involved in morphogenesis GO:0010927 183 0.036
purine containing compound catabolic process GO:0072523 75 0.036
neurological system process GO:0050877 53 0.036
multi organism behavior GO:0051705 389 0.036
cell morphogenesis GO:0000902 163 0.036
purine nucleotide metabolic process GO:0006163 95 0.035
regulation of synapse assembly GO:0051963 2 0.035
Fly
guanosine containing compound metabolic process GO:1901068 49 0.035
phagocytosis engulfment GO:0006911 98 0.035
actin filament based process GO:0030029 191 0.034
negative regulation of vulval development GO:0040027 206 0.034
homeostatic process GO:0042592 51 0.034
genitalia development GO:0048806 741 0.034
cellular nitrogen compound catabolic process GO:0044270 119 0.033
positive regulation of multicellular organism growth GO:0040018 352 0.033
nucleic acid metabolic process GO:0090304 299 0.033
response to organic substance GO:0010033 131 0.033
regulation of endocytosis GO:0030100 25 0.033
ribonucleoside triphosphate metabolic process GO:0009199 87 0.033
detection of external stimulus GO:0009581 4 0.032
regulation of cellular component organization GO:0051128 248 0.032
Fly
cellular component morphogenesis GO:0032989 318 0.032
negative regulation of nematode larval development GO:0061064 208 0.032
multi organism reproductive behavior GO:0044705 387 0.032
regulation of transport GO:0051049 91 0.031
regulation of signal transduction GO:0009966 135 0.031
Fly
generation of neurons GO:0048699 235 0.031
purine ribonucleotide catabolic process GO:0009154 75 0.031
purine nucleoside catabolic process GO:0006152 75 0.031
centrosomal and pronuclear rotation GO:0035047 6 0.030
negative regulation of gene expression epigenetic GO:0045814 2 0.030
chromatin modification GO:0016568 32 0.030
purine nucleoside metabolic process GO:0042278 92 0.030
purine containing compound metabolic process GO:0072521 95 0.030
cell part morphogenesis GO:0032990 152 0.030
membrane invagination GO:0010324 98 0.030
regulation of protein metabolic process GO:0051246 81 0.029
post embryonic organ development GO:0048569 336 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.029
localization of cell GO:0051674 313 0.028
multicellular organismal reproductive process GO:0048609 815 0.028
cell proliferation GO:0008283 116 0.028
regulation of multicellular organism growth GO:0040014 373 0.028
neurogenesis GO:0022008 236 0.028
muscle structure development GO:0061061 191 0.028
gamete generation GO:0007276 461 0.028
organic cyclic compound biosynthetic process GO:1901362 195 0.028
regulation of gene expression epigenetic GO:0040029 163 0.028
apoptotic cell clearance GO:0043277 111 0.027
regulation of catalytic activity GO:0050790 78 0.027
regulation of neuron projection development GO:0010975 31 0.027
regulation of actin filament based process GO:0032970 22 0.027
golgi vesicle transport GO:0048193 3 0.027
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.026
determination of adult lifespan GO:0008340 812 0.026
carbohydrate derivative metabolic process GO:1901135 141 0.026
regulation of post embryonic development GO:0048580 260 0.026
cellular response to organic substance GO:0071310 119 0.026
oviposition GO:0018991 364 0.025
establishment of synaptic vesicle localization GO:0097480 21 0.025
cellular component movement GO:0006928 388 0.025
cellular protein metabolic process GO:0044267 279 0.025
organonitrogen compound catabolic process GO:1901565 90 0.025
purine ribonucleoside catabolic process GO:0046130 75 0.024
molting cycle GO:0042303 281 0.024
nucleoside metabolic process GO:0009116 99 0.024
meiotic nuclear division GO:0007126 300 0.024
lamellipodium assembly GO:0030032 2 0.024
negative regulation of gene expression GO:0010629 217 0.024
cellular protein complex assembly GO:0043623 178 0.023
Human
cell division GO:0051301 262 0.023
striated muscle cell differentiation GO:0051146 158 0.023
multicellular organism growth GO:0035264 385 0.023
nucleoside triphosphate metabolic process GO:0009141 87 0.023
negative regulation of multicellular organismal process GO:0051241 236 0.023
organic cyclic compound catabolic process GO:1901361 119 0.022
response to abiotic stimulus GO:0009628 152 0.022
regulation of meiotic cell cycle GO:0051445 136 0.022
gtp catabolic process GO:0006184 46 0.022
development of primary sexual characteristics GO:0045137 840 0.022
multi organism reproductive process GO:0044703 867 0.022
regulation of rna biosynthetic process GO:2001141 165 0.022
secondary metabolite biosynthetic process GO:0044550 3 0.022
single organism behavior GO:0044708 83 0.022
meiotic cell cycle GO:0051321 335 0.022
catabolic process GO:0009056 318 0.022
epithelium development GO:0060429 68 0.022
regulation of nematode larval development GO:0061062 260 0.022
cell migration GO:0016477 306 0.021
ribonucleoside metabolic process GO:0009119 98 0.021
nucleoside triphosphate catabolic process GO:0009143 72 0.021
positive regulation of transport GO:0051050 32 0.021
protein complex biogenesis GO:0070271 186 0.021
Human
inductive cell migration GO:0040039 145 0.021
myofibril assembly GO:0030239 154 0.021
negative regulation of cellular metabolic process GO:0031324 95 0.020
regulation of neuron differentiation GO:0045664 40 0.020
aromatic compound catabolic process GO:0019439 116 0.020
posttranscriptional gene silencing by rna GO:0035194 143 0.020
defense response GO:0006952 296 0.020
rna metabolic process GO:0016070 228 0.020
heterocycle biosynthetic process GO:0018130 187 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
regulation of cell communication GO:0010646 176 0.020
Fly
nucleobase containing small molecule metabolic process GO:0055086 115 0.019
regulation of programmed cell death GO:0043067 50 0.019
muscle cell differentiation GO:0042692 171 0.019
nucleotide catabolic process GO:0009166 77 0.019
gene silencing by rna GO:0031047 143 0.019
positive regulation of metabolic process GO:0009893 187 0.019
meiotic chromosome segregation GO:0045132 139 0.019
cellular protein localization GO:0034613 75 0.019
rna interference GO:0016246 137 0.019
ribose phosphate metabolic process GO:0019693 99 0.019
ribonucleoside catabolic process GO:0042454 77 0.019
axon development GO:0061564 163 0.019
regeneration GO:0031099 4 0.019
posttranscriptional regulation of gene expression GO:0010608 166 0.018
purine nucleoside triphosphate metabolic process GO:0009144 87 0.018
single organism catabolic process GO:0044712 129 0.018
positive regulation of locomotion GO:0040017 42 0.018
synaptic vesicle transport GO:0048489 21 0.018
regulation of response to stimulus GO:0048583 243 0.018
Fly
engulfment of apoptotic cell GO:0043652 94 0.018
macromolecule modification GO:0043412 218 0.018
neuron differentiation GO:0030182 217 0.018
regulation of organelle organization GO:0033043 164 0.018
regulation of cell death GO:0010941 65 0.018
organic substance transport GO:0071702 113 0.018
endomembrane system organization GO:0010256 22 0.018
organic substance catabolic process GO:1901575 294 0.018
positive regulation of phosphorus metabolic process GO:0010562 56 0.017
positive regulation of ras protein signal transduction GO:0046579 7 0.017
neuron projection development GO:0031175 187 0.017
organic substance biosynthetic process GO:1901576 323 0.017
organ morphogenesis GO:0009887 67 0.017
biological adhesion GO:0022610 21 0.017
regulation of apoptotic process GO:0042981 36 0.017
system process GO:0003008 136 0.017
sexual reproduction GO:0019953 546 0.017
actomyosin structure organization GO:0031032 154 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
Fly
regulation of cell development GO:0060284 49 0.016
synaptic vesicle localization GO:0097479 22 0.016
response to chemical GO:0042221 356 0.016
reproductive behavior GO:0019098 387 0.016
positive regulation of nucleotide catabolic process GO:0030813 28 0.016
regulation of mapk cascade GO:0043408 23 0.015
ribonucleoside triphosphate catabolic process GO:0009203 72 0.015
aromatic compound biosynthetic process GO:0019438 192 0.015
protein metabolic process GO:0019538 422 0.015
muscle cell development GO:0055001 158 0.015
organic acid metabolic process GO:0006082 47 0.015
innate immune response GO:0045087 190 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
regulation of cell cycle process GO:0010564 145 0.015
vesicle localization GO:0051648 24 0.014
cytoskeleton organization GO:0007010 339 0.014
regulation of hydrolase activity GO:0051336 45 0.014
regulation of small gtpase mediated signal transduction GO:0051056 41 0.014
myosin filament organization GO:0031033 138 0.014
negative regulation of metabolic process GO:0009892 240 0.014
negative regulation of cell communication GO:0010648 61 0.014
Fly
sensory organ morphogenesis GO:0090596 2 0.014
rna biosynthetic process GO:0032774 169 0.014
protein modification process GO:0036211 207 0.014
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 2 0.014
vulval development GO:0040025 333 0.014
pigment biosynthetic process GO:0046148 2 0.014
regulation of biosynthetic process GO:0009889 189 0.013
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.013
nervous system development GO:0007399 253 0.013
Fly
nucleic acid templated transcription GO:0097659 169 0.013
positive regulation of signal transduction GO:0009967 40 0.013
negative regulation of macromolecule metabolic process GO:0010605 229 0.013
regulation of ras protein signal transduction GO:0046578 41 0.013
regulation of cellular component movement GO:0051270 62 0.013
nuclear migration GO:0007097 54 0.013
striated muscle cell development GO:0055002 157 0.013
internal peptidyl lysine acetylation GO:0018393 3 0.013
regulation of reproductive process GO:2000241 66 0.013
cell recognition GO:0008037 85 0.013
positive regulation of catalytic activity GO:0043085 59 0.013
female gamete generation GO:0007292 254 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.013
regulation of neurotransmitter levels GO:0001505 36 0.012
secretion GO:0046903 147 0.012
embryonic morphogenesis GO:0048598 152 0.012
regulation of phagocytosis engulfment GO:0060099 17 0.012
nucleobase containing compound biosynthetic process GO:0034654 184 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
response to wounding GO:0009611 4 0.012
establishment of nucleus localization GO:0040023 55 0.012
meiotic cell cycle process GO:1903046 170 0.012
adult behavior GO:0030534 3 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
cellular protein modification process GO:0006464 207 0.012
cuticle development GO:0042335 100 0.012
adult locomotory behavior GO:0008344 1 0.012
secondary metabolic process GO:0019748 3 0.012
secretion by cell GO:0032940 138 0.012
single fertilization GO:0007338 61 0.012
skeletal muscle organ development GO:0060538 3 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of protein serine threonine kinase activity GO:0071900 18 0.012
endosomal transport GO:0016197 26 0.012
Human
synaptic vesicle recycling GO:0036465 3 0.012
amine metabolic process GO:0009308 15 0.012
regulation of vulval development GO:0040028 248 0.012
organelle fission GO:0048285 363 0.012
neurotransmitter secretion GO:0007269 26 0.011
g protein coupled receptor signaling pathway GO:0007186 46 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
Fly
chromatin remodeling GO:0006338 2 0.011
protein complex assembly GO:0006461 186 0.011
Human
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.011
regulation of molecular function GO:0065009 89 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
negative regulation of programmed cell death GO:0043069 19 0.011
vesicle organization GO:0016050 15 0.011
Human
regulation of nitrogen compound metabolic process GO:0051171 222 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.011
chromosome segregation GO:0007059 180 0.011
cellular macromolecule biosynthetic process GO:0034645 247 0.011
peptidyl amino acid modification GO:0018193 58 0.011
neuron projection morphogenesis GO:0048812 114 0.011
positive regulation of signaling GO:0023056 66 0.011
positive regulation of gtp catabolic process GO:0033126 28 0.010
receptor metabolic process GO:0043112 6 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.010
pigment metabolic process GO:0042440 2 0.010
regulation of apoptotic signaling pathway GO:2001233 1 0.010
regulation of transcription dna templated GO:0006355 164 0.010
plasma membrane organization GO:0007009 9 0.010
establishment of protein localization to membrane GO:0090150 3 0.010
protein oligomerization GO:0051259 4 0.010
cellular response to inorganic substance GO:0071241 3 0.010

ehs-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.016
immune system disease DOID:2914 0 0.015
hematopoietic system disease DOID:74 0 0.015
congenital hypoplastic anemia DOID:1342 0 0.010
aplastic anemia DOID:12449 0 0.010
bone marrow disease DOID:4961 0 0.010
anemia DOID:2355 0 0.010