Caenorhabditis elegans

133 known processes

lin-14 (CELE_T25C12.1)

Protein LIN-14

lin-14 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ development GO:0048513 1102 0.358
regulation of nitrogen compound metabolic process GO:0051171 222 0.292
single organism reproductive process GO:0044702 1196 0.263
regulation of developmental process GO:0050793 684 0.228
regulation of multicellular organismal process GO:0051239 726 0.226
embryo development GO:0009790 3052 0.209
post embryonic development GO:0009791 2152 0.205
embryo development ending in birth or egg hatching GO:0009792 2992 0.204
locomotion GO:0040011 1634 0.187
heterocycle biosynthetic process GO:0018130 187 0.186
nucleic acid templated transcription GO:0097659 169 0.180
rna biosynthetic process GO:0032774 169 0.178
regulation of rna biosynthetic process GO:2001141 165 0.177
gene expression GO:0010467 412 0.171
organelle organization GO:0006996 783 0.168
regulation of rna metabolic process GO:0051252 173 0.165
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.163
cellular nitrogen compound biosynthetic process GO:0044271 192 0.157
organic cyclic compound biosynthetic process GO:1901362 195 0.156
regulation of biological quality GO:0065008 741 0.153
signaling GO:0023052 401 0.153
regulation of nucleic acid templated transcription GO:1903506 165 0.152
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.146
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.144
nucleic acid metabolic process GO:0090304 299 0.143
transport GO:0006810 1093 0.142
organ morphogenesis GO:0009887 67 0.140
regulation of transcription dna templated GO:0006355 164 0.140
developmental process involved in reproduction GO:0003006 1165 0.138
regulation of multicellular organismal development GO:2000026 317 0.136
positive regulation of rna biosynthetic process GO:1902680 102 0.136
growth GO:0040007 562 0.134
nucleobase containing compound metabolic process GO:0006139 406 0.132
reproductive system development GO:0061458 850 0.131
regulation of biosynthetic process GO:0009889 189 0.131
rna metabolic process GO:0016070 228 0.128
regulation of metabolic process GO:0019222 478 0.128
gonad development GO:0008406 840 0.126
transcription dna templated GO:0006351 168 0.125
cell development GO:0048468 696 0.124
sex differentiation GO:0007548 909 0.123
regulation of macromolecule metabolic process GO:0060255 421 0.123
organic substance biosynthetic process GO:1901576 323 0.122
positive regulation of rna metabolic process GO:0051254 103 0.119
cellular biosynthetic process GO:0044249 315 0.119
positive regulation of cellular process GO:0048522 332 0.119
cellular macromolecule biosynthetic process GO:0034645 247 0.119
hermaphrodite genitalia development GO:0040035 734 0.117
cellular component movement GO:0006928 388 0.114
aromatic compound biosynthetic process GO:0019438 192 0.113
single organism signaling GO:0044700 401 0.113
behavior GO:0007610 527 0.111
positive regulation of macromolecule metabolic process GO:0010604 149 0.110
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.110
regulation of primary metabolic process GO:0080090 292 0.109
biosynthetic process GO:0009058 323 0.107
positive regulation of cellular biosynthetic process GO:0031328 109 0.107
cell motility GO:0048870 313 0.106
system process GO:0003008 136 0.106
reproductive structure development GO:0048608 850 0.104
establishment of localization GO:0051234 1171 0.102
regulation of gene expression GO:0010468 366 0.101
multi organism reproductive process GO:0044703 867 0.099
epithelium development GO:0060429 68 0.098
death GO:0016265 547 0.096
macromolecule localization GO:0033036 771 0.095
positive regulation of metabolic process GO:0009893 187 0.095
positive regulation of transcription dna templated GO:0045893 102 0.094
regulation of cellular metabolic process GO:0031323 305 0.094
endocytosis GO:0006897 819 0.093
multicellular organism reproduction GO:0032504 819 0.092
body morphogenesis GO:0010171 620 0.092
response to chemical GO:0042221 356 0.092
cellular localization GO:0051641 360 0.090
multicellular organism growth GO:0035264 385 0.089
development of primary sexual characteristics GO:0045137 840 0.089
vesicle mediated transport GO:0016192 852 0.089
cellular component morphogenesis GO:0032989 318 0.089
cell fate commitment GO:0045165 139 0.088
positive regulation of developmental process GO:0051094 408 0.088
tissue development GO:0009888 112 0.085
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.085
positive regulation of gene expression GO:0010628 112 0.084
cell cycle process GO:0022402 482 0.084
response to external stimulus GO:0009605 289 0.083
negative regulation of biological process GO:0048519 567 0.083
macromolecule biosynthetic process GO:0009059 250 0.081
axon development GO:0061564 163 0.079
multicellular organismal reproductive process GO:0048609 815 0.079
cell cycle GO:0007049 526 0.079
anatomical structure formation involved in morphogenesis GO:0048646 250 0.078
aging GO:0007568 812 0.078
apoptotic process GO:0006915 478 0.077
cell migration GO:0016477 306 0.077
nucleobase containing compound biosynthetic process GO:0034654 184 0.077
cell morphogenesis GO:0000902 163 0.076
lipid localization GO:0010876 573 0.073
maintenance of location GO:0051235 580 0.072
regulation of vulval development GO:0040028 248 0.072
multicellular organismal reproductive behavior GO:0033057 384 0.071
muscle structure development GO:0061061 191 0.070
neuron projection development GO:0031175 187 0.070
regulation of cellular biosynthetic process GO:0031326 189 0.069
multicellular organismal aging GO:0010259 812 0.068
taxis GO:0042330 128 0.068
lipid storage GO:0019915 565 0.067
receptor mediated endocytosis GO:0006898 715 0.066
multi organism behavior GO:0051705 389 0.066
cell projection organization GO:0030030 231 0.066
sexual reproduction GO:0019953 546 0.066
neuron projection guidance GO:0097485 82 0.065
positive regulation of nucleic acid templated transcription GO:1903508 102 0.065
positive regulation of multicellular organismal process GO:0051240 417 0.065
axonogenesis GO:0007409 102 0.065
reproductive behavior GO:0019098 387 0.064
regulation of multicellular organism growth GO:0040014 373 0.064
negative regulation of developmental process GO:0051093 227 0.063
single organism organelle organization GO:1902589 501 0.063
neuron differentiation GO:0030182 217 0.063
head development GO:0060322 1 0.063
neuron projection morphogenesis GO:0048812 114 0.063
establishment of localization in cell GO:0051649 318 0.063
determination of adult lifespan GO:0008340 812 0.062
regulation of growth GO:0040008 409 0.062
axon guidance GO:0007411 82 0.061
single organism localization GO:1902578 518 0.061
transcription from rna polymerase ii promoter GO:0006366 149 0.061
post embryonic organ development GO:0048569 336 0.060
cell death GO:0008219 547 0.059
positive regulation of growth GO:0045927 369 0.059
positive regulation of multicellular organism growth GO:0040018 352 0.058
regulation of post embryonic development GO:0048580 260 0.058
chemotaxis GO:0006935 120 0.058
negative regulation of multicellular organismal process GO:0051241 236 0.057
generation of neurons GO:0048699 235 0.057
sensory organ morphogenesis GO:0090596 2 0.057
positive regulation of cellular metabolic process GO:0031325 178 0.057
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.056
gamete generation GO:0007276 461 0.056
neuron development GO:0048666 199 0.056
vulval development GO:0040025 333 0.055
programmed cell death GO:0012501 500 0.055
nervous system development GO:0007399 253 0.053
regulation of macromolecule biosynthetic process GO:0010556 189 0.053
cell morphogenesis involved in differentiation GO:0000904 112 0.052
single organism transport GO:0044765 447 0.052
regulation of developmental growth GO:0048638 389 0.051
multi multicellular organism process GO:0044706 390 0.051
positive regulation of biosynthetic process GO:0009891 109 0.051
digestive tract development GO:0048565 122 0.050
oviposition GO:0018991 364 0.050
neurogenesis GO:0022008 236 0.050
negative regulation of vulval development GO:0040027 206 0.049
regulation of cellular component organization GO:0051128 248 0.049
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.049
multi organism reproductive behavior GO:0044705 387 0.048
developmental growth GO:0048589 412 0.048
regulation of nematode larval development GO:0061062 260 0.048
protein metabolic process GO:0019538 422 0.047
positive regulation of nematode larval development GO:0061063 54 0.047
cellular component assembly GO:0022607 293 0.046
positive regulation of developmental growth GO:0048639 354 0.046
localization of cell GO:0051674 313 0.046
female gamete generation GO:0007292 254 0.044
embryonic morphogenesis GO:0048598 152 0.044
cytoskeleton organization GO:0007010 339 0.044
defense response GO:0006952 296 0.043
cell part morphogenesis GO:0032990 152 0.043
protein complex subunit organization GO:0071822 280 0.043
organelle fission GO:0048285 363 0.043
cellular protein metabolic process GO:0044267 279 0.041
regulation of response to stimulus GO:0048583 243 0.041
tube development GO:0035295 126 0.040
digestive system development GO:0055123 122 0.040
genitalia development GO:0048806 741 0.040
negative regulation of nematode larval development GO:0061064 208 0.040
cellular macromolecular complex assembly GO:0034622 184 0.039
response to wounding GO:0009611 4 0.039
muscle tissue development GO:0060537 1 0.038
germ cell development GO:0007281 351 0.038
signal transduction GO:0007165 317 0.037
negative regulation of gene expression GO:0010629 217 0.037
macromolecular complex assembly GO:0065003 193 0.037
negative regulation of post embryonic development GO:0048581 208 0.036
digestive tract morphogenesis GO:0048546 76 0.036
negative regulation of cellular process GO:0048523 239 0.036
catabolic process GO:0009056 318 0.035
regulation of localization GO:0032879 194 0.035
cell division GO:0051301 262 0.035
meiotic cell cycle GO:0051321 335 0.034
inductive cell migration GO:0040039 145 0.033
oogenesis GO:0048477 229 0.033
meiotic nuclear division GO:0007126 300 0.033
cellular protein complex assembly GO:0043623 178 0.033
macromolecular complex subunit organization GO:0043933 320 0.033
regulation of gene expression epigenetic GO:0040029 163 0.033
secretion GO:0046903 147 0.033
posttranscriptional regulation of gene expression GO:0010608 166 0.031
secretion by cell GO:0032940 138 0.031
small molecule metabolic process GO:0044281 186 0.031
muscle cell differentiation GO:0042692 171 0.031
organelle localization GO:0051640 127 0.030
positive regulation of neurogenesis GO:0050769 4 0.030
negative regulation of metabolic process GO:0009892 240 0.030
actin cytoskeleton organization GO:0030036 184 0.030
neurological system process GO:0050877 53 0.030
regulation of cell differentiation GO:0045595 81 0.029
protein complex assembly GO:0006461 186 0.029
response to other organism GO:0051707 101 0.029
epithelial tube morphogenesis GO:0060562 1 0.029
epidermis development GO:0008544 24 0.028
protein modification process GO:0036211 207 0.028
posttranscriptional gene silencing GO:0016441 143 0.028
nematode male tail tip morphogenesis GO:0045138 77 0.028
molting cycle GO:0042303 281 0.028
cell projection morphogenesis GO:0048858 148 0.027
regulation of organelle organization GO:0033043 164 0.027
dauer larval development GO:0040024 92 0.027
organelle assembly GO:0070925 214 0.027
positive regulation of vulval development GO:0040026 52 0.026
organic substance catabolic process GO:1901575 294 0.026
gene silencing GO:0016458 143 0.026
negative regulation of macromolecule metabolic process GO:0010605 229 0.026
macromolecule modification GO:0043412 218 0.026
macromolecule catabolic process GO:0009057 202 0.026
regulation of cytoplasmic transport GO:1903649 3 0.025
regulation of nucleocytoplasmic transport GO:0046822 3 0.025
regulation of cell migration GO:0030334 55 0.025
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.025
cellular component biogenesis GO:0044085 297 0.025
protein localization GO:0008104 205 0.025
response to biotic stimulus GO:0009607 101 0.025
regeneration GO:0031099 4 0.024
regulation of meiotic cell cycle GO:0051445 136 0.024
gene silencing by rna GO:0031047 143 0.023
cellular protein modification process GO:0006464 207 0.023
regulation of cell cycle GO:0051726 194 0.023
cellular component assembly involved in morphogenesis GO:0010927 183 0.023
posttranscriptional gene silencing by rna GO:0035194 143 0.023
tissue morphogenesis GO:0048729 65 0.023
negative regulation of neurogenesis GO:0050768 4 0.023
carbohydrate derivative metabolic process GO:1901135 141 0.023
regulation of meiosis GO:0040020 94 0.022
protein complex biogenesis GO:0070271 186 0.022
canonical wnt signaling pathway GO:0060070 3 0.022
regulation of synapse assembly GO:0051963 2 0.022
membrane organization GO:0061024 135 0.021
cellular response to stress GO:0033554 162 0.021
organic substance transport GO:0071702 113 0.021
defense response to other organism GO:0098542 100 0.021
positive regulation of neuron differentiation GO:0045666 4 0.021
muscle cell development GO:0055001 158 0.021
response to external biotic stimulus GO:0043207 101 0.021
regulation of signaling GO:0023051 172 0.021
protein catabolic process GO:0030163 162 0.021
pattern specification process GO:0007389 59 0.021
phagocytosis engulfment GO:0006911 98 0.021
phosphate containing compound metabolic process GO:0006796 232 0.020
organonitrogen compound metabolic process GO:1901564 151 0.020
defense response to bacterium GO:0042742 86 0.020
actomyosin structure organization GO:0031032 154 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.020
male anatomical structure morphogenesis GO:0090598 78 0.020
regulation of signal transduction GO:0009966 135 0.020
striated muscle myosin thick filament assembly GO:0071688 138 0.020
neuromuscular junction development GO:0007528 2 0.020
adult behavior GO:0030534 3 0.020
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.020
regulation of cell motility GO:2000145 57 0.020
rna interference GO:0016246 137 0.019
regulation of locomotion GO:0040012 161 0.019
actin filament based process GO:0030029 191 0.019
chromosome segregation GO:0007059 180 0.019
positive regulation of cell migration GO:0030335 3 0.019
phosphorus metabolic process GO:0006793 232 0.019
neuron recognition GO:0008038 83 0.019
dendrite development GO:0016358 42 0.019
phagocytosis GO:0006909 115 0.018
establishment of organelle localization GO:0051656 123 0.018
intracellular receptor signaling pathway GO:0030522 2 0.018
myofibril assembly GO:0030239 154 0.018
male sex differentiation GO:0046661 86 0.018
cellular catabolic process GO:0044248 199 0.018
regulation of cell communication GO:0010646 176 0.018
positive regulation of locomotion GO:0040017 42 0.018
intracellular signal transduction GO:0035556 96 0.018
myosin filament assembly GO:0031034 138 0.018
myosin filament organization GO:0031033 138 0.018
cellular response to abiotic stimulus GO:0071214 4 0.018
regulation of cell proliferation GO:0042127 105 0.018
cell type specific apoptotic process GO:0097285 4 0.018
regulation of cell division GO:0051302 142 0.018
response to organic substance GO:0010033 131 0.017
response to bacterium GO:0009617 86 0.017
spindle organization GO:0007051 92 0.017
organic acid metabolic process GO:0006082 47 0.017
proteolysis GO:0006508 61 0.017
memory GO:0007613 3 0.017
cell proliferation GO:0008283 116 0.017
skeletal muscle organ development GO:0060538 3 0.017
cellular response to chemical stimulus GO:0070887 129 0.017
rho protein signal transduction GO:0007266 2 0.017
regulation of transport GO:0051049 91 0.017
tube morphogenesis GO:0035239 79 0.017
striated muscle cell differentiation GO:0051146 158 0.016
regulation of organ morphogenesis GO:2000027 4 0.016
regulation of nervous system development GO:0051960 41 0.016
axon extension GO:0048675 37 0.015
regulation of cellular component movement GO:0051270 62 0.015
regulation of cell death GO:0010941 65 0.015
positive regulation of post embryonic development GO:0048582 54 0.015
axonal fasciculation GO:0007413 79 0.015
cell recognition GO:0008037 85 0.015
hatching GO:0035188 48 0.015
regulation of neuron differentiation GO:0045664 40 0.015
positive regulation of cell communication GO:0010647 69 0.015
positive regulation of intracellular transport GO:0032388 2 0.015
pharynx development GO:0060465 51 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.015
striated muscle cell development GO:0055002 157 0.015
establishment of spindle localization GO:0051293 51 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
anterior posterior pattern specification GO:0009952 27 0.015
regulation of cell morphogenesis GO:0022604 40 0.015
meiotic cell cycle process GO:1903046 170 0.015
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.014
oxoacid metabolic process GO:0043436 47 0.014
ribonucleoprotein complex assembly GO:0022618 4 0.014
regulation of cell fate commitment GO:0010453 22 0.014
nucleobase containing small molecule metabolic process GO:0055086 115 0.014
engulfment of apoptotic cell GO:0043652 94 0.014
negative regulation of response to stimulus GO:0048585 73 0.014
neuron projection extension GO:1990138 37 0.014
regulation of response to wounding GO:1903034 1 0.014
microtubule based process GO:0007017 182 0.014
membrane invagination GO:0010324 98 0.014
regulation of nuclear division GO:0051783 115 0.014
purine ribonucleotide metabolic process GO:0009150 95 0.014
regulation of neurogenesis GO:0050767 40 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.014
regulation of cellular component size GO:0032535 40 0.014
mating behavior GO:0007617 32 0.014
cuticle development GO:0042335 100 0.014
negative regulation of cellular biosynthetic process GO:0031327 65 0.014
regulation of cellular protein metabolic process GO:0032268 75 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
adult locomotory behavior GO:0008344 1 0.014
ribonucleotide metabolic process GO:0009259 99 0.013
positive regulation of protein transport GO:0051222 4 0.013
regulation of bmp signaling pathway GO:0030510 3 0.013
regulation of cellular localization GO:0060341 42 0.013
defense response to gram negative bacterium GO:0050829 64 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
immune response GO:0006955 192 0.013
collagen and cuticulin based cuticle development GO:0040002 99 0.013
regulation of behavior GO:0050795 97 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
purine nucleotide metabolic process GO:0006163 95 0.013
cellular protein localization GO:0034613 75 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
bmp signaling pathway GO:0030509 3 0.013
heterocycle catabolic process GO:0046700 119 0.013
nucleoside phosphate metabolic process GO:0006753 108 0.013
apoptotic cell clearance GO:0043277 111 0.013
cellular macromolecule localization GO:0070727 75 0.013
nucleoside metabolic process GO:0009116 99 0.013
cell substrate adhesion GO:0031589 1 0.013
regulation of cell development GO:0060284 49 0.013
glycosyl compound catabolic process GO:1901658 79 0.013
regulation of protein metabolic process GO:0051246 81 0.013
rna localization GO:0006403 3 0.013
organism emergence from protective structure GO:0071684 48 0.013
regulation of epithelial cell proliferation GO:0050678 1 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.012
development of primary male sexual characteristics GO:0046546 4 0.012
ribosome biogenesis GO:0042254 4 0.012
intracellular transport GO:0046907 77 0.012
ribose phosphate metabolic process GO:0019693 99 0.012
glycosyl compound metabolic process GO:1901657 100 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
organic cyclic compound catabolic process GO:1901361 119 0.012
detection of external stimulus GO:0009581 4 0.012
long term memory GO:0007616 2 0.012
negative regulation of gene expression epigenetic GO:0045814 2 0.012
embryonic body morphogenesis GO:0010172 49 0.012
regulation of protein import into nucleus GO:0042306 3 0.012
negative regulation of neuron differentiation GO:0045665 4 0.012
spindle localization GO:0051653 51 0.012
aromatic compound catabolic process GO:0019439 116 0.012
negative regulation of signaling GO:0023057 61 0.012
gastrulation GO:0007369 58 0.012
nucleotide metabolic process GO:0009117 108 0.012
pigmentation GO:0043473 2 0.012
regulation of neuron projection development GO:0010975 31 0.012
regulation of cell cycle process GO:0010564 145 0.012
organophosphate metabolic process GO:0019637 125 0.012
mating GO:0007618 34 0.012
regulation of anatomical structure morphogenesis GO:0022603 51 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
positive regulation of transport GO:0051050 32 0.011
regulation of phosphorus metabolic process GO:0051174 81 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.011
mitotic nuclear division GO:0007067 89 0.011
hormone transport GO:0009914 2 0.011
negative regulation of transcription dna templated GO:0045892 53 0.011
regulation of protein targeting GO:1903533 3 0.011
regulation of cell fate specification GO:0042659 22 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
single organism behavior GO:0044708 83 0.011
calcium mediated signaling GO:0019722 3 0.011
ribonucleoside metabolic process GO:0009119 98 0.011
lipid metabolic process GO:0006629 77 0.011
mitotic spindle organization GO:0007052 81 0.011
single organism biosynthetic process GO:0044711 91 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
innate immune response GO:0045087 190 0.011
protein phosphorylation GO:0006468 85 0.011
regulation of cytoskeleton organization GO:0051493 41 0.011
response to abiotic stimulus GO:0009628 152 0.011
regulation of cation channel activity GO:2001257 3 0.011
meiotic chromosome segregation GO:0045132 139 0.011
developmental cell growth GO:0048588 39 0.011
mitotic cell cycle process GO:1903047 194 0.011
regulation of stem cell differentiation GO:2000736 1 0.010
chromosome organization GO:0051276 104 0.010
regulation of axon extension GO:0030516 20 0.010
positive regulation of cell cycle GO:0045787 55 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.010
regulation of molecular function GO:0065009 89 0.010
positive regulation of phosphate metabolic process GO:0045937 56 0.010
cellular ketone metabolic process GO:0042180 14 0.010
regulation of mitotic cell cycle GO:0007346 76 0.010
negative regulation of cell communication GO:0010648 61 0.010
amine metabolic process GO:0009308 15 0.010
regulation of axonogenesis GO:0050770 24 0.010
establishment of mitotic spindle localization GO:0040001 41 0.010

lin-14 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
nervous system disease DOID:863 0 0.011
organ system cancer DOID:0050686 0 0.011