Caenorhabditis elegans

3 known processes

gdh-1 (CELE_ZK829.4)

Protein GDH-1

gdh-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.894
embryo development ending in birth or egg hatching GO:0009792 2992 0.743
post embryonic development GO:0009791 2152 0.735
phosphorus metabolic process GO:0006793 232 0.658
gamete generation GO:0007276 461 0.622
sexual reproduction GO:0019953 546 0.539
transport GO:0006810 1093 0.482
Human Mouse
locomotion GO:0040011 1634 0.477
purine containing compound metabolic process GO:0072521 95 0.399
phosphate containing compound metabolic process GO:0006796 232 0.398
determination of adult lifespan GO:0008340 812 0.358
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.355
nucleoside metabolic process GO:0009116 99 0.350
cellular component morphogenesis GO:0032989 318 0.330
nucleoside monophosphate metabolic process GO:0009123 46 0.325
single organism reproductive process GO:0044702 1196 0.312
establishment of localization GO:0051234 1171 0.307
Human Mouse
cellular response to chemical stimulus GO:0070887 129 0.285
multicellular organism reproduction GO:0032504 819 0.283
ribonucleoside triphosphate metabolic process GO:0009199 87 0.274
aging GO:0007568 812 0.265
endocytosis GO:0006897 819 0.261
receptor mediated endocytosis GO:0006898 715 0.254
germ cell development GO:0007281 351 0.254
ribonucleoside monophosphate metabolic process GO:0009161 45 0.253
female gamete generation GO:0007292 254 0.236
developmental process involved in reproduction GO:0003006 1165 0.234
carbohydrate derivative metabolic process GO:1901135 141 0.230
glycosyl compound metabolic process GO:1901657 100 0.225
ribose phosphate metabolic process GO:0019693 99 0.224
purine nucleoside triphosphate metabolic process GO:0009144 87 0.224
multicellular organismal aging GO:0010259 812 0.212
single organism catabolic process GO:0044712 129 0.207
Human
cellular protein metabolic process GO:0044267 279 0.206
organonitrogen compound metabolic process GO:1901564 151 0.203
Human Mouse
development of primary sexual characteristics GO:0045137 840 0.201
cell development GO:0048468 696 0.196
vesicle mediated transport GO:0016192 852 0.191
nucleotide metabolic process GO:0009117 108 0.187
genitalia development GO:0048806 741 0.183
small molecule metabolic process GO:0044281 186 0.175
Human Mouse
negative regulation of biological process GO:0048519 567 0.169
atp metabolic process GO:0046034 42 0.167
multi organism reproductive process GO:0044703 867 0.166
purine nucleotide metabolic process GO:0006163 95 0.165
single organism transport GO:0044765 447 0.165
Human Mouse
growth GO:0040007 562 0.162
single organism signaling GO:0044700 401 0.159
Human Mouse
body morphogenesis GO:0010171 620 0.153
nucleobase containing small molecule metabolic process GO:0055086 115 0.151
gonad development GO:0008406 840 0.150
signaling GO:0023052 401 0.144
Human Mouse
sex differentiation GO:0007548 909 0.136
regulation of signaling GO:0023051 172 0.135
Human Mouse
purine ribonucleotide metabolic process GO:0009150 95 0.134
nervous system development GO:0007399 253 0.128
Human
purine nucleoside metabolic process GO:0042278 92 0.128
death GO:0016265 547 0.127
protein metabolic process GO:0019538 422 0.127
regulation of cellular metabolic process GO:0031323 305 0.125
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.121
multicellular organismal reproductive process GO:0048609 815 0.121
nucleoside phosphate metabolic process GO:0006753 108 0.120
signal transduction GO:0007165 317 0.118
organic substance biosynthetic process GO:1901576 323 0.116
Human
purine ribonucleoside metabolic process GO:0046128 92 0.115
oogenesis GO:0048477 229 0.113
reproductive system development GO:0061458 850 0.111
reproductive structure development GO:0048608 850 0.111
regulation of biological quality GO:0065008 741 0.109
Human Mouse
ribonucleotide metabolic process GO:0009259 99 0.109
apoptotic process GO:0006915 478 0.108
cellular localization GO:0051641 360 0.096
Human Mouse
regulation of multicellular organismal process GO:0051239 726 0.096
phosphorylation GO:0016310 116 0.093
nucleobase containing compound metabolic process GO:0006139 406 0.092
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.090
cellular nitrogen compound biosynthetic process GO:0044271 192 0.090
organophosphate metabolic process GO:0019637 125 0.088
vulval development GO:0040025 333 0.088
positive regulation of cellular process GO:0048522 332 0.087
Human Mouse
cellular component movement GO:0006928 388 0.087
nucleoside phosphate catabolic process GO:1901292 77 0.086
single organism localization GO:1902578 518 0.086
Human Mouse
nucleoside triphosphate metabolic process GO:0009141 87 0.085
aromatic compound biosynthetic process GO:0019438 192 0.083
establishment of localization in cell GO:0051649 318 0.082
Human Mouse
response to abiotic stimulus GO:0009628 152 0.080
organ development GO:0048513 1102 0.080
Human
behavior GO:0007610 527 0.079
regulation of molecular function GO:0065009 89 0.078
purine nucleoside monophosphate metabolic process GO:0009126 43 0.075
cell death GO:0008219 547 0.075
biosynthetic process GO:0009058 323 0.074
Human
cell motility GO:0048870 313 0.074
gene expression GO:0010467 412 0.073
ribonucleoside metabolic process GO:0009119 98 0.072
organic acid metabolic process GO:0006082 47 0.071
Human Mouse
mating behavior GO:0007617 32 0.070
regulation of primary metabolic process GO:0080090 292 0.069
macromolecule localization GO:0033036 771 0.069
positive regulation of cellular metabolic process GO:0031325 178 0.068
programmed cell death GO:0012501 500 0.068
regulation of metabolic process GO:0019222 478 0.068
mitochondrion organization GO:0007005 20 0.067
catabolic process GO:0009056 318 0.067
Human
cellular response to organic substance GO:0071310 119 0.065
cellular protein modification process GO:0006464 207 0.064
lipid storage GO:0019915 565 0.061
macromolecular complex subunit organization GO:0043933 320 0.060
oxoacid metabolic process GO:0043436 47 0.060
Human Mouse
cell projection organization GO:0030030 231 0.059
head development GO:0060322 1 0.058
Human
regulation of developmental process GO:0050793 684 0.058
multicellular organismal reproductive behavior GO:0033057 384 0.057
cell part morphogenesis GO:0032990 152 0.057
meiotic nuclear division GO:0007126 300 0.057
cellular component assembly involved in morphogenesis GO:0010927 183 0.056
macromolecule modification GO:0043412 218 0.056
developmental growth GO:0048589 412 0.055
response to chemical GO:0042221 356 0.055
maintenance of location GO:0051235 580 0.055
cell cell signaling GO:0007267 118 0.053
Human Mouse
lipid localization GO:0010876 573 0.053
organelle organization GO:0006996 783 0.053
actomyosin structure organization GO:0031032 154 0.052
aromatic compound catabolic process GO:0019439 116 0.051
regulation of multicellular organism growth GO:0040014 373 0.048
cellular biosynthetic process GO:0044249 315 0.047
Human
organic cyclic compound biosynthetic process GO:1901362 195 0.047
myofibril assembly GO:0030239 154 0.047
regulation of growth GO:0040008 409 0.047
ion transport GO:0006811 113 0.047
localization of cell GO:0051674 313 0.046
anatomical structure formation involved in morphogenesis GO:0048646 250 0.046
positive regulation of metabolic process GO:0009893 187 0.044
microvillus organization GO:0032528 1 0.044
regulation of developmental growth GO:0048638 389 0.044
regulation of transport GO:0051049 91 0.044
Human Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.043
cation transport GO:0006812 78 0.043
regulation of ion transmembrane transport GO:0034765 19 0.043
response to wounding GO:0009611 4 0.043
striated muscle cell differentiation GO:0051146 158 0.042
positive regulation of developmental growth GO:0048639 354 0.042
protein modification process GO:0036211 207 0.042
negative regulation of macromolecule metabolic process GO:0010605 229 0.042
tube formation GO:0035148 2 0.041
hermaphrodite genitalia development GO:0040035 734 0.040
striated muscle cell development GO:0055002 157 0.040
cellular catabolic process GO:0044248 199 0.040
Human
positive regulation of phosphate metabolic process GO:0045937 56 0.040
muscle structure development GO:0061061 191 0.038
regulation of catalytic activity GO:0050790 78 0.038
innate immune response GO:0045087 190 0.038
organic substance catabolic process GO:1901575 294 0.036
Human
muscle cell differentiation GO:0042692 171 0.036
single organism behavior GO:0044708 83 0.035
atp catabolic process GO:0006200 27 0.035
cellular response to stress GO:0033554 162 0.034
single organism organelle organization GO:1902589 501 0.034
carboxylic acid metabolic process GO:0019752 34 0.034
Human Mouse
generation of precursor metabolites and energy GO:0006091 18 0.034
regeneration GO:0031099 4 0.034
response to organic substance GO:0010033 131 0.034
positive regulation of growth GO:0045927 369 0.034
inorganic cation transmembrane transport GO:0098662 46 0.033
ribonucleoside monophosphate biosynthetic process GO:0009156 6 0.033
positive regulation of multicellular organismal process GO:0051240 417 0.033
nucleoside triphosphate catabolic process GO:0009143 72 0.033
actin filament based process GO:0030029 191 0.033
purine nucleoside monophosphate biosynthetic process GO:0009127 4 0.033
protein complex subunit organization GO:0071822 280 0.032
regulation of cell death GO:0010941 65 0.032
actin cytoskeleton organization GO:0030036 184 0.032
protein complex biogenesis GO:0070271 186 0.032
organelle localization GO:0051640 127 0.032
multicellular organism growth GO:0035264 385 0.031
monocarboxylic acid metabolic process GO:0032787 22 0.031
post embryonic organ development GO:0048569 336 0.031
mating GO:0007618 34 0.031
single organism biosynthetic process GO:0044711 91 0.031
Human
positive regulation of macromolecule metabolic process GO:0010604 149 0.030
positive regulation of multicellular organism growth GO:0040018 352 0.030
spermatogenesis GO:0007283 41 0.030
macromolecule biosynthetic process GO:0009059 250 0.029
organophosphate catabolic process GO:0046434 81 0.029
regulation of vulval development GO:0040028 248 0.029
negative regulation of gene expression GO:0010629 217 0.029
anatomical structure homeostasis GO:0060249 11 0.029
cellular ketone metabolic process GO:0042180 14 0.028
regulation of response to stimulus GO:0048583 243 0.028
cell migration GO:0016477 306 0.028
purine nucleotide catabolic process GO:0006195 75 0.028
regulation of gene expression GO:0010468 366 0.027
fertilization GO:0009566 63 0.027
myosin filament assembly GO:0031034 138 0.027
male mating behavior GO:0060179 26 0.027
ribonucleoside catabolic process GO:0042454 77 0.027
proteolysis GO:0006508 61 0.027
synaptic transmission GO:0007268 106 0.027
response to temperature stimulus GO:0009266 66 0.027
response to endogenous stimulus GO:0009719 33 0.027
cellular homeostasis GO:0019725 22 0.026
meiotic cell cycle GO:0051321 335 0.026
positive regulation of developmental process GO:0051094 408 0.026
inductive cell migration GO:0040039 145 0.026
cellular component assembly GO:0022607 293 0.026
organelle fission GO:0048285 363 0.026
regulation of phosphorus metabolic process GO:0051174 81 0.026
response to hermaphrodite contact GO:0034606 10 0.026
regulation of phosphate metabolic process GO:0019220 81 0.025
negative regulation of cellular process GO:0048523 239 0.025
glycosyl compound catabolic process GO:1901658 79 0.025
male gamete generation GO:0048232 41 0.025
inorganic ion transmembrane transport GO:0098660 54 0.025
multi organism behavior GO:0051705 389 0.025
organonitrogen compound catabolic process GO:1901565 90 0.024
Human
nucleoside catabolic process GO:0009164 78 0.024
carbohydrate metabolic process GO:0005975 34 0.024
purine nucleoside monophosphate catabolic process GO:0009128 28 0.024
regulation of nitrogen compound metabolic process GO:0051171 222 0.023
negative regulation of metabolic process GO:0009892 240 0.023
single organism carbohydrate metabolic process GO:0044723 29 0.023
purine nucleoside triphosphate catabolic process GO:0009146 72 0.023
tissue development GO:0009888 112 0.022
muscle cell development GO:0055001 158 0.022
multi multicellular organism process GO:0044706 390 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.022
lipid metabolic process GO:0006629 77 0.022
regulation of signal transduction GO:0009966 135 0.022
organonitrogen compound biosynthetic process GO:1901566 44 0.022
Human
negative regulation of nematode larval development GO:0061064 208 0.022
ribonucleoside triphosphate biosynthetic process GO:0009201 4 0.021
system process GO:0003008 136 0.021
regulation of cellular component organization GO:0051128 248 0.021
regulation of localization GO:0032879 194 0.021
Human Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.021
cellular component biogenesis GO:0044085 297 0.020
neuron development GO:0048666 199 0.020
protein complex assembly GO:0006461 186 0.020
apoptotic mitochondrial changes GO:0008637 2 0.020
cellular macromolecule biosynthetic process GO:0034645 247 0.020
microvillus assembly GO:0030033 1 0.020
regulation of cell communication GO:0010646 176 0.019
Human Mouse
negative regulation of vulval development GO:0040027 206 0.019
nucleoside triphosphate biosynthetic process GO:0009142 4 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.019
neuron projection development GO:0031175 187 0.019
negative regulation of response to stimulus GO:0048585 73 0.019
monovalent inorganic cation transport GO:0015672 33 0.019
cytoskeleton organization GO:0007010 339 0.019
cellular respiration GO:0045333 9 0.018
regulation of cellular protein metabolic process GO:0032268 75 0.018
macromolecule catabolic process GO:0009057 202 0.018
membrane organization GO:0061024 135 0.018
oviposition GO:0018991 364 0.018
nucleotide catabolic process GO:0009166 77 0.018
striated muscle myosin thick filament assembly GO:0071688 138 0.018
regulation of protein metabolic process GO:0051246 81 0.018
cellular nitrogen compound catabolic process GO:0044270 119 0.017
regulation of ion transport GO:0043269 39 0.017
carbohydrate derivative catabolic process GO:1901136 82 0.017
cell cycle process GO:0022402 482 0.017
carboxylic acid catabolic process GO:0046395 3 0.017
Human
negative regulation of biosynthetic process GO:0009890 65 0.017
coenzyme metabolic process GO:0006732 9 0.016
organelle assembly GO:0070925 214 0.016
cell morphogenesis GO:0000902 163 0.016
regulation of lipid metabolic process GO:0019216 4 0.016
neuromuscular junction development GO:0007528 2 0.016
reproductive behavior GO:0019098 387 0.016
ribonucleoside triphosphate catabolic process GO:0009203 72 0.016
generation of neurons GO:0048699 235 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.016
transmembrane transport GO:0055085 110 0.016
carbohydrate derivative biosynthetic process GO:1901137 46 0.016
oxidative phosphorylation GO:0006119 11 0.016
cellular macromolecular complex assembly GO:0034622 184 0.016
molting cycle GO:0042303 281 0.016
response to oxygen containing compound GO:1901700 44 0.016
cell cycle GO:0007049 526 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.016
regulation of reproductive process GO:2000241 66 0.015
response to biotic stimulus GO:0009607 101 0.015
intracellular transport GO:0046907 77 0.015
response to inorganic substance GO:0010035 50 0.015
learning or memory GO:0007611 27 0.015
cellular protein complex assembly GO:0043623 178 0.015
regulation of biosynthetic process GO:0009889 189 0.015
heterocycle biosynthetic process GO:0018130 187 0.015
purine nucleotide transport GO:0015865 2 0.015
nucleobase containing compound biosynthetic process GO:0034654 184 0.015
meiotic cell cycle process GO:1903046 170 0.015
myosin filament organization GO:0031033 138 0.015
single organism intracellular transport GO:1902582 70 0.015
regulation of lipid biosynthetic process GO:0046890 1 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
regulation of programmed cell death GO:0043067 50 0.015
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.014
organophosphate biosynthetic process GO:0090407 26 0.014
oxidoreduction coenzyme metabolic process GO:0006733 8 0.014
cuticle development GO:0042335 100 0.014
multi organism reproductive behavior GO:0044705 387 0.014
gene silencing by rna GO:0031047 143 0.014
negative regulation of cellular biosynthetic process GO:0031327 65 0.014
purine ribonucleoside monophosphate biosynthetic process GO:0009168 4 0.014
regulation of multicellular organismal development GO:2000026 317 0.014
cell division GO:0051301 262 0.014
purine containing compound catabolic process GO:0072523 75 0.014
regulation of nucleocytoplasmic transport GO:0046822 3 0.014
atp biosynthetic process GO:0006754 4 0.014
positive regulation of phosphorus metabolic process GO:0010562 56 0.014
purine ribonucleoside catabolic process GO:0046130 75 0.014
posttranscriptional gene silencing GO:0016441 143 0.013
regulation of behavior GO:0050795 97 0.013
organic acid catabolic process GO:0016054 3 0.013
Human
negative regulation of signaling GO:0023057 61 0.013
purine ribonucleotide catabolic process GO:0009154 75 0.013
regulation of rna biosynthetic process GO:2001141 165 0.013
negative regulation of multicellular organismal process GO:0051241 236 0.013
regulation of cell proliferation GO:0042127 105 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.013
response to other organism GO:0051707 101 0.013
regulation of macromolecule biosynthetic process GO:0010556 189 0.013
positive regulation of cell death GO:0010942 38 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
regulation of rna metabolic process GO:0051252 173 0.012
purine nucleoside catabolic process GO:0006152 75 0.012
necrotic cell death GO:0070265 29 0.012
neurogenesis GO:0022008 236 0.012
regulation of nematode larval development GO:0061062 260 0.012
mitotic cell cycle process GO:1903047 194 0.012
macromolecular complex assembly GO:0065003 193 0.012
gene silencing GO:0016458 143 0.012
negative regulation of cell communication GO:0010648 61 0.012
adenine nucleotide transport GO:0051503 2 0.012
organic cyclic compound catabolic process GO:1901361 119 0.012
regulation of organelle organization GO:0033043 164 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
neurotransmitter transport GO:0006836 32 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
Human Mouse
feeding behavior GO:0007631 70 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
neurological system process GO:0050877 53 0.012
positive regulation of neurogenesis GO:0050769 4 0.011
oxidation reduction process GO:0055114 59 0.011
Human Mouse
sensory organ morphogenesis GO:0090596 2 0.011
neuron differentiation GO:0030182 217 0.011
regulation of gene expression epigenetic GO:0040029 163 0.011
cell type specific apoptotic process GO:0097285 4 0.011
regulation of apoptotic process GO:0042981 36 0.011
posttranscriptional regulation of gene expression GO:0010608 166 0.011
translation GO:0006412 37 0.011
phagocytosis GO:0006909 115 0.011
response to heat GO:0009408 50 0.011
response to oxidative stress GO:0006979 42 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
axon development GO:0061564 163 0.011
spindle organization GO:0007051 92 0.011
negative regulation of developmental process GO:0051093 227 0.011
amine metabolic process GO:0009308 15 0.010
taxis GO:0042330 128 0.010
response to mechanical stimulus GO:0009612 28 0.010
response to unfolded protein GO:0006986 71 0.010
intracellular signal transduction GO:0035556 96 0.010
apoptotic cell clearance GO:0043277 111 0.010
nucleus localization GO:0051647 55 0.010
memory GO:0007613 3 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.010

gdh-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.035
Human
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
inherited metabolic disorder DOID:655 0 0.016
Human