Caenorhabditis elegans

19 known processes

mml-1 (CELE_T20B12.6)

Protein MML-1

mml-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.583
embryo development GO:0009790 3052 0.540
locomotion GO:0040011 1634 0.408
organ development GO:0048513 1102 0.366
muscle tissue development GO:0060537 1 0.299
rna biosynthetic process GO:0032774 169 0.275
Human Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.268
regulation of nematode larval development GO:0061062 260 0.257
vulval development GO:0040025 333 0.230
positive regulation of multicellular organismal process GO:0051240 417 0.224
post embryonic development GO:0009791 2152 0.214
regulation of anatomical structure size GO:0090066 46 0.209
regulation of vulval development GO:0040028 248 0.209
cell development GO:0048468 696 0.199
negative regulation of biological process GO:0048519 567 0.194
Human Mouse
regulation of post embryonic development GO:0048580 260 0.192
sex differentiation GO:0007548 909 0.190
biosynthetic process GO:0009058 323 0.180
Human Mouse
regulation of multicellular organismal process GO:0051239 726 0.171
single organism reproductive process GO:0044702 1196 0.164
growth GO:0040007 562 0.163
body morphogenesis GO:0010171 620 0.162
oxoacid metabolic process GO:0043436 47 0.161
Human Mouse
development of primary sexual characteristics GO:0045137 840 0.157
gonad development GO:0008406 840 0.156
regulation of developmental process GO:0050793 684 0.156
negative regulation of post embryonic development GO:0048581 208 0.153
regulation of developmental growth GO:0048638 389 0.150
cellular macromolecule biosynthetic process GO:0034645 247 0.149
Human Mouse
axon development GO:0061564 163 0.146
negative regulation of developmental process GO:0051093 227 0.144
aging GO:0007568 812 0.143
cellular nitrogen compound biosynthetic process GO:0044271 192 0.142
Human Mouse
transport GO:0006810 1093 0.140
multicellular organismal aging GO:0010259 812 0.139
organic cyclic compound biosynthetic process GO:1901362 195 0.138
Human Mouse
multicellular organism reproduction GO:0032504 819 0.137
macromolecule localization GO:0033036 771 0.135
organelle fission GO:0048285 363 0.134
reproductive structure development GO:0048608 850 0.133
multi multicellular organism process GO:0044706 390 0.132
gamete generation GO:0007276 461 0.129
axon guidance GO:0007411 82 0.129
regulation of multicellular organismal development GO:2000026 317 0.128
single organism localization GO:1902578 518 0.126
skeletal muscle organ development GO:0060538 3 0.124
determination of adult lifespan GO:0008340 812 0.123
heterocycle biosynthetic process GO:0018130 187 0.122
Human Mouse
developmental growth GO:0048589 412 0.120
regulation of rna biosynthetic process GO:2001141 165 0.117
Human Mouse
post embryonic organ development GO:0048569 336 0.116
phosphorylation GO:0016310 116 0.115
Human
reproductive system development GO:0061458 850 0.114
cell cycle process GO:0022402 482 0.112
Human
positive regulation of nematode larval development GO:0061063 54 0.112
response to external stimulus GO:0009605 289 0.112
regulation of nucleic acid templated transcription GO:1903506 165 0.109
Human Mouse
organic substance biosynthetic process GO:1901576 323 0.107
Human Mouse
establishment of localization GO:0051234 1171 0.104
generation of neurons GO:0048699 235 0.104
regulation of biological quality GO:0065008 741 0.103
Mouse
organelle organization GO:0006996 783 0.102
multicellular organism growth GO:0035264 385 0.100
negative regulation of nematode larval development GO:0061064 208 0.098
cell cycle GO:0007049 526 0.098
Human
cell migration GO:0016477 306 0.097
muscle organ development GO:0007517 26 0.096
regulation of metabolic process GO:0019222 478 0.095
Human Mouse
regulation of localization GO:0032879 194 0.092
neuron differentiation GO:0030182 217 0.092
multi organism behavior GO:0051705 389 0.091
amine catabolic process GO:0009310 1 0.090
aromatic compound biosynthetic process GO:0019438 192 0.089
Human Mouse
multicellular organismal reproductive process GO:0048609 815 0.089
chemotaxis GO:0006935 120 0.088
genitalia development GO:0048806 741 0.087
sexual reproduction GO:0019953 546 0.086
hermaphrodite genitalia development GO:0040035 734 0.086
positive regulation of developmental growth GO:0048639 354 0.085
behavior GO:0007610 527 0.085
gene expression GO:0010467 412 0.083
Human Mouse
digestive tract development GO:0048565 122 0.083
rna metabolic process GO:0016070 228 0.083
Human Mouse
positive regulation of growth GO:0045927 369 0.083
neuron projection guidance GO:0097485 82 0.083
neuron projection development GO:0031175 187 0.082
regulation of growth GO:0040008 409 0.080
lipid localization GO:0010876 573 0.080
macromolecule biosynthetic process GO:0009059 250 0.079
Human Mouse
meiotic cell cycle GO:0051321 335 0.079
signaling GO:0023052 401 0.079
Mouse
regulation of cell cycle GO:0051726 194 0.078
Human
positive regulation of developmental process GO:0051094 408 0.077
nucleic acid metabolic process GO:0090304 299 0.076
Human Mouse
transcription dna templated GO:0006351 168 0.076
Human Mouse
vesicle mediated transport GO:0016192 852 0.075
nucleobase containing compound biosynthetic process GO:0034654 184 0.074
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 229 0.074
Human Mouse
negative regulation of cellular process GO:0048523 239 0.073
Human Mouse
cell fate commitment GO:0045165 139 0.072
single organism signaling GO:0044700 401 0.072
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.072
Human Mouse
regulation of cellular component organization GO:0051128 248 0.070
cell motility GO:0048870 313 0.069
cellular localization GO:0051641 360 0.069
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.068
oviposition GO:0018991 364 0.068
molting cycle GO:0042303 281 0.068
regulation of multicellular organism growth GO:0040014 373 0.068
reproductive behavior GO:0019098 387 0.066
cellular protein metabolic process GO:0044267 279 0.066
Human
regulation of cell communication GO:0010646 176 0.065
secretion by cell GO:0032940 138 0.064
multi organism reproductive process GO:0044703 867 0.064
positive regulation of macromolecule metabolic process GO:0010604 149 0.063
Mouse
developmental process involved in reproduction GO:0003006 1165 0.063
lipid storage GO:0019915 565 0.062
neuron development GO:0048666 199 0.062
maintenance of location GO:0051235 580 0.062
response to abiotic stimulus GO:0009628 152 0.061
muscle structure development GO:0061061 191 0.061
cellular component movement GO:0006928 388 0.060
localization of cell GO:0051674 313 0.060
tissue morphogenesis GO:0048729 65 0.059
transcription from rna polymerase ii promoter GO:0006366 149 0.059
Human Mouse
regulation of signaling GO:0023051 172 0.059
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.058
sensory organ morphogenesis GO:0090596 2 0.058
muscle cell development GO:0055001 158 0.057
negative regulation of metabolic process GO:0009892 240 0.057
Human Mouse
cellular component morphogenesis GO:0032989 318 0.057
protein modification process GO:0036211 207 0.056
Human
dauer larval development GO:0040024 92 0.056
nervous system development GO:0007399 253 0.055
negative regulation of vulval development GO:0040027 206 0.055
small molecule metabolic process GO:0044281 186 0.054
Human Mouse
pattern specification process GO:0007389 59 0.054
programmed cell death GO:0012501 500 0.053
tissue development GO:0009888 112 0.052
carboxylic acid metabolic process GO:0019752 34 0.052
Human Mouse
regulation of catalytic activity GO:0050790 78 0.051
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.050
Mouse
single organism transport GO:0044765 447 0.050
organic acid metabolic process GO:0006082 47 0.049
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 109 0.049
Mouse
axonogenesis GO:0007409 102 0.049
response to wounding GO:0009611 4 0.049
positive regulation of multicellular organism growth GO:0040018 352 0.047
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.046
phosphate containing compound metabolic process GO:0006796 232 0.046
Human
embryonic morphogenesis GO:0048598 152 0.046
negative regulation of gene expression GO:0010629 217 0.045
Mouse
cellular biosynthetic process GO:0044249 315 0.045
Human Mouse
cell division GO:0051301 262 0.045
single organism biosynthetic process GO:0044711 91 0.044
Human Mouse
response to chemical GO:0042221 356 0.043
Mouse
regulation of intracellular signal transduction GO:1902531 77 0.042
multi organism reproductive behavior GO:0044705 387 0.042
neuron projection morphogenesis GO:0048812 114 0.042
regulation of response to stimulus GO:0048583 243 0.042
cellular protein modification process GO:0006464 207 0.041
Human
regulation of cellular component size GO:0032535 40 0.041
anatomical structure formation involved in morphogenesis GO:0048646 250 0.041
system process GO:0003008 136 0.041
regulation of cellular biosynthetic process GO:0031326 189 0.040
Human Mouse
cell projection organization GO:0030030 231 0.038
neurogenesis GO:0022008 236 0.038
taxis GO:0042330 128 0.038
muscle cell differentiation GO:0042692 171 0.037
multicellular organismal reproductive behavior GO:0033057 384 0.037
signal transduction GO:0007165 317 0.037
Mouse
developmental cell growth GO:0048588 39 0.037
organonitrogen compound metabolic process GO:1901564 151 0.037
Human
positive regulation of post embryonic development GO:0048582 54 0.037
regulation of primary metabolic process GO:0080090 292 0.035
Human Mouse
endocytosis GO:0006897 819 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.035
Mouse
intracellular signal transduction GO:0035556 96 0.035
positive regulation of neuron differentiation GO:0045666 4 0.035
neurological system process GO:0050877 53 0.035
organic substance transport GO:0071702 113 0.035
catabolic process GO:0009056 318 0.035
Human Mouse
epithelium development GO:0060429 68 0.034
negative regulation of cellular metabolic process GO:0031324 95 0.034
Human Mouse
germ cell development GO:0007281 351 0.034
cell death GO:0008219 547 0.033
regulation of rna metabolic process GO:0051252 173 0.033
Human Mouse
negative regulation of bmp signaling pathway GO:0030514 1 0.033
intraspecies interaction between organisms GO:0051703 3 0.033
regulation of cell cycle process GO:0010564 145 0.033
Human
receptor mediated endocytosis GO:0006898 715 0.032
positive regulation of biosynthetic process GO:0009891 109 0.032
Human Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.032
Mouse
organ morphogenesis GO:0009887 67 0.031
regulation of cell proliferation GO:0042127 105 0.031
Human
apoptotic process GO:0006915 478 0.031
secretion GO:0046903 147 0.031
cellular amino acid metabolic process GO:0006520 15 0.031
protein localization GO:0008104 205 0.031
muscle organ morphogenesis GO:0048644 4 0.030
macromolecular complex subunit organization GO:0043933 320 0.030
positive regulation of stress activated mapk cascade GO:0032874 3 0.030
regulation of macromolecule biosynthetic process GO:0010556 189 0.030
Human Mouse
macromolecule modification GO:0043412 218 0.030
Human
single organism catabolic process GO:0044712 129 0.030
Human Mouse
neuromuscular junction development GO:0007528 2 0.029
cell proliferation GO:0008283 116 0.028
Human
regulation of meiotic cell cycle GO:0051445 136 0.028
protein metabolic process GO:0019538 422 0.028
Human
cellular protein localization GO:0034613 75 0.028
canonical wnt signaling pathway GO:0060070 3 0.028
cellular ketone metabolic process GO:0042180 14 0.028
Mouse
epithelial tube morphogenesis GO:0060562 1 0.028
cellular component biogenesis GO:0044085 297 0.028
positive regulation of vulval development GO:0040026 52 0.027
cell morphogenesis GO:0000902 163 0.027
positive regulation of cellular process GO:0048522 332 0.027
Human Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.027
Human Mouse
monocarboxylic acid metabolic process GO:0032787 22 0.026
Human Mouse
regulation of molecular function GO:0065009 89 0.026
single organism organelle organization GO:1902589 501 0.026
cellular component assembly GO:0022607 293 0.026
developmental growth involved in morphogenesis GO:0060560 37 0.026
nucleobase containing compound metabolic process GO:0006139 406 0.025
Human Mouse
response to heat GO:0009408 50 0.025
cellular catabolic process GO:0044248 199 0.025
Human Mouse
nucleic acid templated transcription GO:0097659 169 0.025
Human Mouse
negative regulation of cell communication GO:0010648 61 0.025
tube development GO:0035295 126 0.024
regulation of cell size GO:0008361 30 0.024
regulation of phosphorus metabolic process GO:0051174 81 0.024
Human
response to temperature stimulus GO:0009266 66 0.024
cgmp metabolic process GO:0046068 2 0.024
regulation of cellular protein metabolic process GO:0032268 75 0.024
Human
positive regulation of neuron projection development GO:0010976 4 0.024
proteolysis GO:0006508 61 0.024
synaptic target recognition GO:0008039 3 0.023
cellular amine metabolic process GO:0044106 15 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.023
regulation of biosynthetic process GO:0009889 189 0.023
Human Mouse
peptidyl amino acid modification GO:0018193 58 0.023
Human
regulation of gene expression epigenetic GO:0040029 163 0.022
carboxylic acid biosynthetic process GO:0046394 21 0.022
Mouse
regulation of neurotransmitter levels GO:0001505 36 0.022
adult behavior GO:0030534 3 0.022
striated muscle cell development GO:0055002 157 0.022
regulation of mitotic cell cycle GO:0007346 76 0.022
digestive system development GO:0055123 122 0.022
cell projection morphogenesis GO:0048858 148 0.022
posttranscriptional regulation of gene expression GO:0010608 166 0.022
amine metabolic process GO:0009308 15 0.022
cell morphogenesis involved in differentiation GO:0000904 112 0.021
cell substrate adhesion GO:0031589 1 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.021
Human Mouse
organic substance catabolic process GO:1901575 294 0.021
Human Mouse
regulation of bmp signaling pathway GO:0030510 3 0.021
regulation of cellular metabolic process GO:0031323 305 0.021
Human Mouse
negative regulation of protein metabolic process GO:0051248 27 0.020
Human
regulation of signal transduction GO:0009966 135 0.020
bmp signaling pathway GO:0030509 3 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
regulation of cellular catabolic process GO:0031329 51 0.020
Human Mouse
phosphorus metabolic process GO:0006793 232 0.020
Human
regulation of nitrogen compound metabolic process GO:0051171 222 0.020
Human Mouse
regulation of protein metabolic process GO:0051246 81 0.020
Human
protein phosphorylation GO:0006468 85 0.020
Human
synaptic vesicle recycling GO:0036465 3 0.020
cytoskeleton organization GO:0007010 339 0.020
organonitrogen compound biosynthetic process GO:1901566 44 0.020
inductive cell migration GO:0040039 145 0.020
death GO:0016265 547 0.020
carboxylic acid catabolic process GO:0046395 3 0.020
cell surface receptor signaling pathway GO:0007166 149 0.020
regulation of synapse assembly GO:0051963 2 0.019
striated muscle cell differentiation GO:0051146 158 0.019
axonal fasciculation GO:0007413 79 0.019
cellular response to stress GO:0033554 162 0.019
protein complex subunit organization GO:0071822 280 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
Mouse
regulation of phosphorylation GO:0042325 45 0.019
Human
nucleotide metabolic process GO:0009117 108 0.019
Human
regulation of lipid metabolic process GO:0019216 4 0.019
Human Mouse
positive regulation of molecular function GO:0044093 61 0.019
regulation of transcription dna templated GO:0006355 164 0.018
Human Mouse
axon extension GO:0048675 37 0.018
protein complex biogenesis GO:0070271 186 0.018
neuron projection extension GO:1990138 37 0.018
digestive tract morphogenesis GO:0048546 76 0.018
negative regulation of signal transduction GO:0009968 60 0.018
regulation of stem cell differentiation GO:2000736 1 0.018
ras protein signal transduction GO:0007265 31 0.018
organelle assembly GO:0070925 214 0.018
cellular macromolecular complex assembly GO:0034622 184 0.017
cellular macromolecule localization GO:0070727 75 0.017
cognition GO:0050890 27 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.017
Human Mouse
membrane organization GO:0061024 135 0.017
regulation of organ morphogenesis GO:2000027 4 0.017
dendrite development GO:0016358 42 0.017
lipid oxidation GO:0034440 1 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.017
Mouse
cell type specific apoptotic process GO:0097285 4 0.017
regulation of catabolic process GO:0009894 57 0.017
Human Mouse
female gamete generation GO:0007292 254 0.017
negative regulation of signaling GO:0023057 61 0.017
positive regulation of signaling GO:0023056 66 0.017
regulation of locomotion GO:0040012 161 0.016
actomyosin structure organization GO:0031032 154 0.016
tube morphogenesis GO:0035239 79 0.016
regulation of phosphate metabolic process GO:0019220 81 0.016
Human
detection of external stimulus GO:0009581 4 0.016
collagen and cuticulin based cuticle development GO:0040002 99 0.016
regulation of behavior GO:0050795 97 0.016
oogenesis GO:0048477 229 0.016
regeneration GO:0031099 4 0.016
positive regulation of rna biosynthetic process GO:1902680 102 0.016
Mouse
intracellular receptor signaling pathway GO:0030522 2 0.016
dosage compensation GO:0007549 13 0.015
protein complex assembly GO:0006461 186 0.015
regulation of nucleocytoplasmic transport GO:0046822 3 0.015
regulation of cell division GO:0051302 142 0.015
ribonucleoprotein complex assembly GO:0022618 4 0.015
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.015
gastrulation GO:0007369 58 0.015
muscle fiber development GO:0048747 2 0.015
regulation of meiosis GO:0040020 94 0.015
single organism carbohydrate metabolic process GO:0044723 29 0.015
Human Mouse
regulation of organelle organization GO:0033043 164 0.015
positive regulation of cellular metabolic process GO:0031325 178 0.015
Human Mouse
calcium mediated signaling GO:0019722 3 0.015
ion transport GO:0006811 113 0.015
synaptic transmission GO:0007268 106 0.015
small gtpase mediated signal transduction GO:0007264 32 0.014
negative regulation of neurogenesis GO:0050768 4 0.014
establishment of localization in cell GO:0051649 318 0.014
carbohydrate metabolic process GO:0005975 34 0.014
Human Mouse
actin filament based process GO:0030029 191 0.014
regulation of nervous system development GO:0051960 41 0.014
regulation of mapk cascade GO:0043408 23 0.014
adult locomotory behavior GO:0008344 1 0.014
chromosome organization GO:0051276 104 0.014
neuron recognition GO:0008038 83 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
myosin filament assembly GO:0031034 138 0.014
positive regulation of jnk cascade GO:0046330 3 0.014
positive regulation of organ growth GO:0046622 4 0.014
regulation of cell death GO:0010941 65 0.014
cellular macromolecule catabolic process GO:0044265 73 0.013
carbohydrate derivative metabolic process GO:1901135 141 0.013
Human
nucleoside phosphate metabolic process GO:0006753 108 0.013
Human
response to organic substance GO:0010033 131 0.013
Mouse
regulation of cytoplasmic transport GO:1903649 3 0.013
regulation of gene expression GO:0010468 366 0.013
Human Mouse
protein oligomerization GO:0051259 4 0.013
positive regulation of protein metabolic process GO:0051247 45 0.013
macromolecular complex assembly GO:0065003 193 0.013
monosaccharide metabolic process GO:0005996 2 0.013
regulation of neuron projection development GO:0010975 31 0.013
cell growth GO:0016049 44 0.013
head development GO:0060322 1 0.013
negative regulation of response to stimulus GO:0048585 73 0.013
regulation of axonogenesis GO:0050770 24 0.013
pharynx development GO:0060465 51 0.013
actin cytoskeleton organization GO:0030036 184 0.013
wnt signaling pathway GO:0016055 27 0.013
regulation of response to stress GO:0080134 28 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.013
Mouse
cellular response to organic substance GO:0071310 119 0.013
Mouse
regulation of cell motility GO:2000145 57 0.013
oxidation reduction process GO:0055114 59 0.012
small molecule biosynthetic process GO:0044283 38 0.012
Mouse
response to extracellular stimulus GO:0009991 38 0.012
innate immune response GO:0045087 190 0.012
regulation of translation GO:0006417 19 0.012
regulation of cell migration GO:0030334 55 0.012
ribonucleotide metabolic process GO:0009259 99 0.012
Human
regulation of protein ubiquitination GO:0031396 3 0.012
regulation of canonical wnt signaling pathway GO:0060828 1 0.012
response to acid chemical GO:0001101 4 0.012
myosin filament organization GO:0031033 138 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
cell part morphogenesis GO:0032990 152 0.011
myofibril assembly GO:0030239 154 0.011
synaptic vesicle endocytosis GO:0048488 3 0.011
positive regulation of cell cycle GO:0045787 55 0.011
translation GO:0006412 37 0.011
immune response GO:0006955 192 0.011
response to topologically incorrect protein GO:0035966 82 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 2 0.011
Human Mouse
detection of abiotic stimulus GO:0009582 4 0.011
regulation of anatomical structure morphogenesis GO:0022603 51 0.011
mitotic cell cycle process GO:1903047 194 0.011
endoderm development GO:0007492 20 0.011
regulation of cell differentiation GO:0045595 81 0.011
meiotic chromosome segregation GO:0045132 139 0.011
negative regulation of molecular function GO:0044092 20 0.010
neuron apoptotic process GO:0051402 4 0.010
response to inorganic substance GO:0010035 50 0.010
translational initiation GO:0006413 2 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.010
Human Mouse
posttranscriptional gene silencing GO:0016441 143 0.010
defense response GO:0006952 296 0.010
carbohydrate biosynthetic process GO:0016051 4 0.010
positive regulation of phosphorus metabolic process GO:0010562 56 0.010
rna interference GO:0016246 137 0.010
organophosphate metabolic process GO:0019637 125 0.010
Human

mml-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.010