Caenorhabditis elegans

14 known processes

his-45 (CELE_B0035.10)

Protein HIS-45

his-45 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract development GO:0048565 122 0.998
Worm
meiotic cell cycle process GO:1903046 170 0.997
Yeast
meiotic cell cycle GO:0051321 335 0.995
Yeast
pharynx development GO:0060465 51 0.993
Worm
gonad development GO:0008406 840 0.992
Worm
digestive system development GO:0055123 122 0.991
Worm
embryo development GO:0009790 3052 0.990
reproductive system development GO:0061458 850 0.987
Worm
tube development GO:0035295 126 0.984
Worm
sexual reproduction GO:0019953 546 0.984
Yeast
reproductive structure development GO:0048608 850 0.983
Worm
developmental process involved in reproduction GO:0003006 1165 0.968
Yeast Worm
development of primary sexual characteristics GO:0045137 840 0.966
Worm
genitalia development GO:0048806 741 0.965
Worm
hermaphrodite genitalia development GO:0040035 734 0.963
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.959
post embryonic development GO:0009791 2152 0.938
single organism reproductive process GO:0044702 1196 0.929
Yeast Worm
locomotion GO:0040011 1634 0.917
Worm
organ development GO:0048513 1102 0.917
Worm
cellular macromolecule biosynthetic process GO:0034645 247 0.850
Yeast
sex differentiation GO:0007548 909 0.799
Worm
multicellular organism reproduction GO:0032504 819 0.793
multicellular organismal reproductive behavior GO:0033057 384 0.751
regulation of gene expression GO:0010468 366 0.743
multicellular organismal reproductive process GO:0048609 815 0.732
transcription dna templated GO:0006351 168 0.727
Yeast
meiotic nuclear division GO:0007126 300 0.722
oviposition GO:0018991 364 0.722
negative regulation of gene expression epigenetic GO:0045814 2 0.697
regulation of primary metabolic process GO:0080090 292 0.658
cellular response to dna damage stimulus GO:0006974 41 0.576
Yeast
body morphogenesis GO:0010171 620 0.472
Worm
negative regulation of biological process GO:0048519 567 0.455
nucleobase containing compound metabolic process GO:0006139 406 0.454
Yeast
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.450
dna metabolic process GO:0006259 74 0.450
Yeast
dna repair GO:0006281 23 0.442
Yeast
gene expression GO:0010467 412 0.430
Yeast
negative regulation of macromolecule metabolic process GO:0010605 229 0.428
organelle organization GO:0006996 783 0.420
protein metabolic process GO:0019538 422 0.413
meiotic chromosome segregation GO:0045132 139 0.410
fertilization GO:0009566 63 0.393
pronuclear migration GO:0035046 51 0.385
regulation of nitrogen compound metabolic process GO:0051171 222 0.372
rna metabolic process GO:0016070 228 0.368
Yeast
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.350
multi organism reproductive process GO:0044703 867 0.350
Yeast
regulation of macromolecule metabolic process GO:0060255 421 0.344
vesicle mediated transport GO:0016192 852 0.331
nucleic acid templated transcription GO:0097659 169 0.330
Yeast
negative regulation of metabolic process GO:0009892 240 0.325
negative regulation of biosynthetic process GO:0009890 65 0.316
organic substance biosynthetic process GO:1901576 323 0.292
Yeast
macromolecule biosynthetic process GO:0009059 250 0.288
Yeast
negative regulation of gene expression GO:0010629 217 0.287
regulation of rna metabolic process GO:0051252 173 0.282
rna biosynthetic process GO:0032774 169 0.281
Yeast
negative regulation of cellular process GO:0048523 239 0.274
receptor mediated endocytosis GO:0006898 715 0.267
single organism organelle organization GO:1902589 501 0.267
establishment of localization GO:0051234 1171 0.250
determination of adult lifespan GO:0008340 812 0.249
Worm
gamete generation GO:0007276 461 0.247
multicellular organismal aging GO:0010259 812 0.240
Worm
regulation of transcription dna templated GO:0006355 164 0.228
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.224
regulation of metabolic process GO:0019222 478 0.223
establishment of localization in cell GO:0051649 318 0.222
apoptotic process GO:0006915 478 0.221
aging GO:0007568 812 0.206
Worm
negative regulation of nucleic acid templated transcription GO:1903507 53 0.200
regulation of cellular metabolic process GO:0031323 305 0.198
germ cell development GO:0007281 351 0.192
negative regulation of transcription dna templated GO:0045892 53 0.190
nucleic acid metabolic process GO:0090304 299 0.188
Yeast
vulval development GO:0040025 333 0.185
gene silencing GO:0016458 143 0.182
cellular protein metabolic process GO:0044267 279 0.182
cellular localization GO:0051641 360 0.176
negative regulation of cellular metabolic process GO:0031324 95 0.174
endocytosis GO:0006897 819 0.169
programmed cell death GO:0012501 500 0.168
regulation of cellular biosynthetic process GO:0031326 189 0.163
nucleobase containing compound biosynthetic process GO:0034654 184 0.162
Yeast
macromolecule localization GO:0033036 771 0.162
biosynthetic process GO:0009058 323 0.161
Yeast
regulation of meiotic cell cycle GO:0051445 136 0.152
death GO:0016265 547 0.150
multi organism behavior GO:0051705 389 0.148
cellular nitrogen compound biosynthetic process GO:0044271 192 0.146
Yeast
cell cycle process GO:0022402 482 0.135
Yeast
transport GO:0006810 1093 0.129
regulation of organelle organization GO:0033043 164 0.123
regulation of biological quality GO:0065008 741 0.121
regulation of gene expression epigenetic GO:0040029 163 0.117
cell death GO:0008219 547 0.115
negative regulation of rna biosynthetic process GO:1902679 53 0.114
regulation of mitotic metaphase anaphase transition GO:0030071 5 0.113
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.113
organelle fission GO:0048285 363 0.111
single fertilization GO:0007338 61 0.109
catabolic process GO:0009056 318 0.108
regulation of cell division GO:0051302 142 0.105
mitotic nuclear division GO:0007067 89 0.104
cell cycle GO:0007049 526 0.104
Yeast
mitotic cell cycle process GO:1903047 194 0.104
chromosome organization GO:0051276 104 0.102
female gamete generation GO:0007292 254 0.102
aromatic compound biosynthetic process GO:0019438 192 0.100
Yeast
cellular biosynthetic process GO:0044249 315 0.097
Yeast
organic substance catabolic process GO:1901575 294 0.097
regulation of nucleic acid templated transcription GO:1903506 165 0.096
multi organism reproductive behavior GO:0044705 387 0.095
transcription from rna polymerase ii promoter GO:0006366 149 0.095
cellular component morphogenesis GO:0032989 318 0.094
chromatin assembly or disassembly GO:0006333 1 0.093
cellular macromolecular complex assembly GO:0034622 184 0.089
oogenesis GO:0048477 229 0.086
ubiquitin dependent protein catabolic process GO:0006511 32 0.082
lipid localization GO:0010876 573 0.081
macromolecular complex subunit organization GO:0043933 320 0.081
lipid storage GO:0019915 565 0.079
maintenance of location GO:0051235 580 0.078
regulation of cellular catabolic process GO:0031329 51 0.077
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.075
cellular component assembly GO:0022607 293 0.074
organic cyclic compound biosynthetic process GO:1901362 195 0.074
Yeast
macromolecule catabolic process GO:0009057 202 0.074
behavior GO:0007610 527 0.073
reproductive behavior GO:0019098 387 0.073
defense response GO:0006952 296 0.071
macromolecule modification GO:0043412 218 0.070
negative regulation of catabolic process GO:0009895 9 0.069
regulation of cellular component organization GO:0051128 248 0.069
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.068
secretion GO:0046903 147 0.068
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.068
single organism transport GO:0044765 447 0.067
multi multicellular organism process GO:0044706 390 0.066
regulation of biosynthetic process GO:0009889 189 0.064
regulation of nuclear division GO:0051783 115 0.063
anatomical structure formation involved in morphogenesis GO:0048646 250 0.062
Yeast
muscle structure development GO:0061061 191 0.062
nucleus organization GO:0006997 38 0.061
cell division GO:0051301 262 0.061
macromolecular complex assembly GO:0065003 193 0.061
cell development GO:0048468 696 0.060
chromatin organization GO:0006325 32 0.059
protein catabolic process GO:0030163 162 0.059
posttranscriptional regulation of gene expression GO:0010608 166 0.059
chromosome segregation GO:0007059 180 0.058
negative regulation of cellular biosynthetic process GO:0031327 65 0.058
cellular response to stress GO:0033554 162 0.057
Yeast
organelle assembly GO:0070925 214 0.057
regulation of meiosis GO:0040020 94 0.055
oocyte axis specification GO:0007309 2 0.055
regulation of rna biosynthetic process GO:2001141 165 0.053
positive regulation of cellular metabolic process GO:0031325 178 0.052
regulation of vulval development GO:0040028 248 0.051
cellular component assembly involved in morphogenesis GO:0010927 183 0.051
mitotic cell cycle checkpoint GO:0007093 5 0.051
protein complex subunit organization GO:0071822 280 0.049
spindle checkpoint GO:0031577 4 0.048
cellular catabolic process GO:0044248 199 0.048
heterocycle biosynthetic process GO:0018130 187 0.047
Yeast
post embryonic organ development GO:0048569 336 0.047
multicellular organism growth GO:0035264 385 0.046
regulation of growth GO:0040008 409 0.046
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.045
negative regulation of nematode larval development GO:0061064 208 0.045
regulation of cell cycle process GO:0010564 145 0.044
regulation of catabolic process GO:0009894 57 0.044
regulation of cell cycle GO:0051726 194 0.043
ribose phosphate metabolic process GO:0019693 99 0.043
single organism localization GO:1902578 518 0.042
negative regulation of cellular protein metabolic process GO:0032269 27 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.041
secretion by cell GO:0032940 138 0.039
regulation of macromolecule biosynthetic process GO:0010556 189 0.039
muscle cell development GO:0055001 158 0.038
muscle cell differentiation GO:0042692 171 0.038
positive regulation of cellular process GO:0048522 332 0.037
actin filament based process GO:0030029 191 0.037
protein modification process GO:0036211 207 0.036
positive regulation of cellular biosynthetic process GO:0031328 109 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.035
cytoskeleton organization GO:0007010 339 0.034
negative regulation of cellular component organization GO:0051129 33 0.034
myofibril assembly GO:0030239 154 0.033
ribosome biogenesis GO:0042254 4 0.033
histone modification GO:0016570 30 0.033
regulation of nematode larval development GO:0061062 260 0.032
single organism catabolic process GO:0044712 129 0.032
purine ribonucleoside metabolic process GO:0046128 92 0.032
proteolysis GO:0006508 61 0.031
actin cytoskeleton organization GO:0030036 184 0.031
cellular protein modification process GO:0006464 207 0.031
immune response GO:0006955 192 0.031
negative regulation of protein metabolic process GO:0051248 27 0.031
regulation of developmental growth GO:0048638 389 0.030
negative regulation of cellular protein catabolic process GO:1903363 4 0.030
striated muscle cell development GO:0055002 157 0.030
negative regulation of chromosome segregation GO:0051985 4 0.028
positive regulation of multicellular organism growth GO:0040018 352 0.028
cell motility GO:0048870 313 0.028
growth GO:0040007 562 0.027
regulation of developmental process GO:0050793 684 0.027
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 5 0.027
cellular protein complex assembly GO:0043623 178 0.027
actomyosin structure organization GO:0031032 154 0.027
intracellular signal transduction GO:0035556 96 0.026
oocyte construction GO:0007308 2 0.026
regulation of multicellular organism growth GO:0040014 373 0.025
cellular protein catabolic process GO:0044257 37 0.025
sister chromatid segregation GO:0000819 46 0.025
regulation of multicellular organismal process GO:0051239 726 0.025
positive regulation of developmental growth GO:0048639 354 0.024
posttranscriptional gene silencing by rna GO:0035194 143 0.023
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 4 0.023
positive regulation of growth GO:0045927 369 0.023
mitotic sister chromatid segregation GO:0000070 38 0.023
negative regulation of mitotic metaphase anaphase transition GO:0045841 4 0.022
protein neddylation GO:0045116 3 0.022
positive regulation of metabolic process GO:0009893 187 0.022
modification dependent protein catabolic process GO:0019941 32 0.021
modification dependent macromolecule catabolic process GO:0043632 32 0.021
innate immune response GO:0045087 190 0.021
oocyte development GO:0048599 44 0.021
myosin filament organization GO:0031033 138 0.020
negative regulation of cellular catabolic process GO:0031330 9 0.020
protein complex assembly GO:0006461 186 0.020
regulation of mitosis GO:0007088 18 0.020
developmental growth GO:0048589 412 0.019
ras protein signal transduction GO:0007265 31 0.019
posttranscriptional gene silencing GO:0016441 143 0.019
cellular amine metabolic process GO:0044106 15 0.018
negative regulation of proteasomal protein catabolic process GO:1901799 4 0.018
negative regulation of vulval development GO:0040027 206 0.018
cellular component biogenesis GO:0044085 297 0.018
rna interference GO:0016246 137 0.018
positive regulation of developmental process GO:0051094 408 0.017
inductive cell migration GO:0040039 145 0.017
organonitrogen compound metabolic process GO:1901564 151 0.017
cell proliferation GO:0008283 116 0.017
chromosome separation GO:0051304 19 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.016
regulation of protein catabolic process GO:0042176 13 0.016
ribonucleoprotein complex assembly GO:0022618 4 0.016
regulation of mitotic sister chromatid segregation GO:0033047 16 0.016
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 4 0.016
striated muscle myosin thick filament assembly GO:0071688 138 0.016
cellular macromolecule catabolic process GO:0044265 73 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.015
negative regulation of mitotic sister chromatid segregation GO:0033048 4 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 5 0.015
carbohydrate derivative metabolic process GO:1901135 141 0.014
protein complex biogenesis GO:0070271 186 0.014
response to wounding GO:0009611 4 0.014
oocyte differentiation GO:0009994 45 0.014
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.014
positive regulation of macromolecule metabolic process GO:0010604 149 0.014
negative regulation of cell cycle phase transition GO:1901988 6 0.013
myosin filament assembly GO:0031034 138 0.013
regulation of cellular protein metabolic process GO:0032268 75 0.013
chromatin modification GO:0016568 32 0.013
negative regulation of developmental process GO:0051093 227 0.012
mitotic sister chromatid separation GO:0051306 13 0.012
purine containing compound metabolic process GO:0072521 95 0.012
purine ribonucleotide metabolic process GO:0009150 95 0.012
pole plasm assembly GO:0007315 2 0.012
gene silencing by rna GO:0031047 143 0.012
nucleus localization GO:0051647 55 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.012
nucleoside metabolic process GO:0009116 99 0.012
regulation of mitotic cell cycle GO:0007346 76 0.012
negative regulation of rna metabolic process GO:0051253 53 0.012
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.012
striated muscle cell differentiation GO:0051146 158 0.012
purine nucleotide metabolic process GO:0006163 95 0.011
negative regulation of protein catabolic process GO:0042177 4 0.011
protein localization GO:0008104 205 0.011
ribonucleoside metabolic process GO:0009119 98 0.011
signal transduction GO:0007165 317 0.011
signaling GO:0023052 401 0.011
rna localization GO:0006403 3 0.011
positive regulation of phosphorus metabolic process GO:0010562 56 0.011
regulation of protein stability GO:0031647 3 0.011
mitotic spindle assembly checkpoint GO:0007094 4 0.011
cell migration GO:0016477 306 0.011
establishment of organelle localization GO:0051656 123 0.010
positive regulation of transcription dna templated GO:0045893 102 0.010
phosphate containing compound metabolic process GO:0006796 232 0.010
negative regulation of multicellular organismal process GO:0051241 236 0.010
neuromuscular junction development GO:0007528 2 0.010
negative regulation of mitosis GO:0045839 4 0.010
mitotic g2 m transition checkpoint GO:0044818 1 0.010
negative regulation of signaling GO:0023057 61 0.010
positive regulation of nucleic acid templated transcription GO:1903508 102 0.010

his-45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020